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JOURNAL ARTICLE
Farzad Alipour, Mana Ahmadraji, Elham Yektadoost, Parvaneh Mohammadi, Hossein Baharvand, Mohsen Basiri
OBJECTIVE: Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic skin fragility and ultimately lethal blistering disease caused by mutations in the COL7A1 gene which is responsible for coding type VII collagen. Investigating the pathological mechanisms and novel candidate therapies for RDEB could be fostered by new cellular models. The aim of this study was to employ CRISPR/Cas9 technology in the development of immortalized COL7A1-deficient keratinocyte cell lines intended for application as a cellular model for RDEB in ex vivo studies...
October 9, 2023: Cell Journal
#22
JOURNAL ARTICLE
Kaveh Same, Parnian Shobeiri, Mohammad-Mahdi Rashidi, Erfan Ghasemi, Sahar Saeedi Moghaddam, Esmaeil Mohammadi, Masoud Masinaei, Niloufar Salehi, Sahar Mohammadi Fateh, Seyed Farzad Maroufi, Elham Abdolhamidi, Mana Moghimi, Zeinab Abbasi-Kangevari, Negar Rezaei, Bagher Larijani
BACKGROUND AND HYPOTHESIS: Schizophrenia is a mental disorder usually presented in adulthood that affects roughly 0.3 percent of the population. The disease contributes to more than 13 million years lived with disability the global burden of disease. The current study aimed to provide new insights into the quality of care in Schizophrenia via the implementation of the newly introduced quality of care index (QCI) into the existing data. STUDY DESIGN: The data from the global burden of disease database was used for schizophrenia...
September 21, 2023: Schizophrenia Bulletin
#23
JOURNAL ARTICLE
Seyed Farzad Maroufi, Parnian Shobeiri, Esmaeil Mohammadi, Sina Azadnajafabad, Mohammad-Reza Malekpour, Erfan Ghasemi, Mohammad-Mahdi Rashidi, Sahar Saeedi Moghaddam, Nazila Rezaei, Yeganeh Sharifnejad Tehrani, Sahar Mohammadi Fateh, Naser Ahmadi, Yosef Farzi, Negar Rezaei, Bagher Larijani
BACKGROUND: Multiple sclerosis (MS) is a common neurologic autoimmune disorder. We have used a newly introduced measure, Quality of Care Index (QCI), which is associated with the efficacy of care given to patients suffering from MS. OBJECTIVE: To report and compare the quality of care given to MS patients in different regions and country. METHOD: Primary measures were retrieved from Global Burden of Disease (GBD) from 1990 to 2019. Secondary measures (mortality to incidence ratio, DALY to prevalence ratio, prevalence to incidence ratio, and YLL to YLD ratio) were combined using Principle Component Analysis (PCA), to form an essential component (QCI) (0-100 index with higher values representing better condition)...
September 21, 2023: Neuroepidemiology
#24
JOURNAL ARTICLE
Amanda Ramos da Cunha, Kelly Compton, Rixing Xu, Rashmi Mishra, Mark Thomas Drangsholt, Jose Leopoldo Ferreira Antunes, Alexander R Kerr, Alistair R Acheson, Dan Lu, Lindsey E Wallace, Jonathan M Kocarnik, Weijia Fu, Frances E Dean, Alyssa Pennini, Hannah Jacqueline Henrikson, Tahiya Alam, Emad Ababneh, Sherief Abd-Elsalam, Meriem Abdoun, Hassan Abidi, Hiwa Abubaker Ali, Eman Abu-Gharbieh, Tigist Demssew Adane, Isaac Yeboah Addo, Aqeel Ahmad, Sajjad Ahmad, Tarik Ahmed Rashid, Maxwell Akonde, Hanadi Al Hamad, Fares Alahdab, Yousef Alimohamadi, Vahid Alipour, Sadeq Ali Al-Maweri, Ubai Alsharif, Alireza Ansari-Moghaddam, Sumadi Lukman Anwar, Anayochukwu Edward Anyasodor, Jalal Arabloo, Aleksandr Y Aravkin, Raphael Taiwo Aruleba, Malke Asaad, Tahira Ashraf, Seyyed Shamsadin Athari, Sameh Attia, Sina Azadnajafabad, Mohammadreza Azangou-Khyavy, Muhammad Badar, Nayereh Baghcheghi, Maciej Banach, Mainak Bardhan, Hiba Jawdat Barqawi, Nasir Z Bashir, Azadeh Bashiri, Habib Benzian, Eduardo Bernabe, Devidas S Bhagat, Vijayalakshmi S Bhojaraja, Tone Bjørge, Souad Bouaoud, Dejana Braithwaite, Nikolay Ivanovich Briko, Daniela Calina, Giulia Carreras, Promit Ananyo Chakraborty, Vijay Kumar Chattu, Akhilanand Chaurasia, Meng Xuan Chen, William C S Cho, Dinh-Toi Chu, Isaac Sunday Chukwu, Eunice Chung, Natália Cruz-Martins, Omid Dadras, Xiaochen Dai, Lalit Dandona, Rakhi Dandona, Parnaz Daneshpajouhnejad, Reza Darvishi Cheshmeh Soltani, Aso Mohammad Darwesh, Sisay Abebe Debela, Meseret Derbew Molla, Fikadu Nugusu Dessalegn, Mostafa Dianati-Nasab, Lankamo Ena Digesa, Shilpi Gupta Dixit, Abhinav Dixit, Shirin Djalalinia, Iman El Sayed, Maha El Tantawi, Daniel Berhanie Enyew, Daniel Asfaw Erku, Rana Ezzeddini, Adeniyi Francis Fagbamigbe, Luca Falzone, Getahun Fetensa, Takeshi Fukumoto, Piyada Gaewkhiew, Silvano Gallus, Mesfin Gebrehiwot, Ahmad Ghashghaee, Paramjit Singh Gill, Mahaveer Golechha, Pouya Goleij, Ricardo Santiago Gomez, Giuseppe Gorini, Andre Luiz Sena Guimaraes, Bhawna Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Gupta, Arvin Haj-Mirzaian, Esam S Halboub, Rabih Halwani, Asif Hanif, Ninuk Hariyani, Mehdi Harorani, Hamidreza Hasani, Abbas M Hassan, Soheil Hassanipour, Mohammed Bheser Hassen, Simon I Hay, Khezar Hayat, Brenda Yuliana Herrera-Serna, Ramesh Holla, Nobuyuki Horita, Mehdi Hosseinzadeh, Salman Hussain, Olayinka Stephen Ilesanmi, Irena M Ilic, Milena D Ilic, Gaetano Isola, Abhishek Jaiswal, Chinmay T Jani, Tahereh Javaheri, Umesh Jayarajah, Shubha Jayaram, Nitin Joseph, Vidya Kadashetti, Eswar Kandaswamy, Shama D Karanth, Ibraheem M Karaye, Joonas H Kauppila, Harkiran Kaur, Mohammad Keykhaei, Yousef Saleh Khader, Himanshu Khajuria, Javad Khanali, Mahalaqua Nazli Khatib, Hamid Reza Khayat Kashani, Mohammad Amin Khazeei Tabari, Min Seo Kim, Farzad Kompani, Hamid Reza Koohestani, G Anil Kumar, Om P Kurmi, Carlo La Vecchia, Dharmesh Kumar Lal, Iván Landires, Savita Lasrado, Caterina Ledda, Yo Han Lee, Massimo Libra, Stephen S Lim, Stefan Listl, Platon D Lopukhov, Ahmad R Mafi, Rashidul Alam Mahumud, Ahmad Azam Malik, Manu Raj Mathur, Sazan Qadir Maulud, Jitendra Kumar Meena, Entezar Mehrabi Nasab, Tomislav Mestrovic, Reza Mirfakhraie, Awoke Misganaw, Sanjeev Misra, Prasanna Mithra, Yousef Mohammad, Mokhtar Mohammadi, Esmaeil Mohammadi, Ali H Mokdad, Mohammad Ali Moni, Paula Moraga, Shane Douglas Morrison, Hamid Reza Mozaffari, Sumaira Mubarik, Christopher J L Murray, Tapas Sadasivan Nair, Sreenivas Narasimha Swamy, Aparna Ichalangod Narayana, Hasan Nassereldine, Zuhair S Natto, Biswa Prakash Nayak, Serban Mircea Negru, Haruna Asura Nggada, Hasti Nouraei, Virginia Nuñez-Samudio, Bogdan Oancea, Andrew T Olagunju, Ahmed Omar Bali, Alicia Padron-Monedero, Jagadish Rao Padubidri, Anamika Pandey, Shahina Pardhan, Jay Patel, Raffaele Pezzani, Zahra Zahid Piracha, Navid Rabiee, Venkatraman Radhakrishnan, Raghu Anekal Radhakrishnan, Amir Masoud Rahmani, Vahid Rahmanian, Chythra R Rao, Sowmya J Rao, Goura Kishor Rath, David Laith Rawaf, Salman Rawaf, Reza Rawassizadeh, Mohammad Sadegh Razeghinia, Nazila Rezaei, Negar Rezaei, Nima Rezaei, Aziz Rezapour, Abanoub Riad, Thomas J Roberts, Esperanza Romero-Rodríguez, Gholamreza Roshandel, Manjula S, Chandan S N, Basema Saddik, Mohammad Reza Saeb, Umar Saeed, Mohsen Safaei, Maryam Sahebazzamani, Amirhossein Sahebkar, Amir Salek Farrokhi, Abdallah M Samy, Milena M Santric-Milicevic, Brijesh Sathian, Maheswar Satpathy, Mario Šekerija, Subramanian Senthilkumaran, Allen Seylani, Omid Shafaat, Hamid R Shahsavari, Erfan Shamsoddin, Mequannent Melaku Sharew, Javad Sharifi-Rad, Jeevan K Shetty, K M Shivakumar, Parnian Shobeiri, Seyed Afshin Shorofi, Sunil Shrestha, Sudeep K Siddappa Malleshappa, Paramdeep Singh, Jasvinder A Singh, Garima Singh, Dhirendra Narain Sinha, Yonatan Solomon, Muhammad Suleman, Rizwan Suliankatchi Abdulkader, Yasaman Taheri Abkenar, Iman M Talaat, Ker-Kan Tan, Abdelghani Tbakhi, Arulmani Thiyagarajan, Amir Tiyuri, Marcos Roberto Tovani-Palone, Bhaskaran Unnikrishnan, Bay Vo, Simona Ruxandra Volovat, Cong Wang, Ronny Westerman, Nuwan Darshana Wickramasinghe, Hong Xiao, Chuanhua Yu, Deniz Yuce, Ismaeel Yunusa, Vesna Zadnik, Iman Zare, Zhi-Jiang Zhang, Mohammad Zoladl, Lisa M Force, Fernando N Hugo
IMPORTANCE: Lip, oral, and pharyngeal cancers are important contributors to cancer burden worldwide, and a comprehensive evaluation of their burden globally, regionally, and nationally is crucial for effective policy planning. OBJECTIVE: To analyze the total and risk-attributable burden of lip and oral cavity cancer (LOC) and other pharyngeal cancer (OPC) for 204 countries and territories and by Socio-demographic Index (SDI) using 2019 Global Burden of Diseases, Injuries, and Risk Factors (GBD) Study estimates...
October 1, 2023: JAMA Oncology
#25
JOURNAL ARTICLE
Narjes Obeidi, Maedeh Darzipour Babolei, Gholamreza Khamisipour, Seyed Amin Mohammadi, Farzad Farhangdost, Sepideh Valipor
INTRODUCTION: Acute lymphoblastic leukemia (ALL) is among the most prevalent child cancers. Moreover, chemotherapy and bone marrow transplantation have failed to secure the survival of patients in some cases. Various researches have revealed that glycogen synthase kinase 3 (GSK-3) inhibitors can contain the growth of some cancers. Furthermore, inositol trisphosphate receptor (IP3R) exists in all cell types and is implicated in metastasis. The application of organic, natural substances offers new prospects for the treatment of this condition...
August 1, 2023: Asian Pacific Journal of Cancer Prevention: APJCP
#26
JOURNAL ARTICLE
Kimiya Gohari, Anoshirvan Kazemnejad, Marjan Mohammadi, Farzad Eskandari, Samaneh Saberi, Maryam Esmaieli, Ali Sheidaei
BACKGROUND: The Naive Bayes (NB) classifier is a powerful supervised algorithm widely used in Machine Learning (ML). However, its effectiveness relies on a strict assumption of conditional independence, which is often violated in real-world scenarios. To address this limitation, various studies have explored extensions of NB that tackle the issue of non-conditional independence in the data. These approaches can be broadly categorized into two main categories: feature selection and structure expansion...
August 21, 2023: BMC Medical Research Methodology
#27
JOURNAL ARTICLE
Habibeh Mohammadi, Hamid Afshar-Zanjani, Farzad Goli, Ammar Hasanzadeh Kashtli, Khadijeh Abolmaali
Background : The main purpose of this study was to delineate the role of motivational structure and traumatic events in the prediction of ambiguity tolerance in patients with irritable bowel syndrome (IBS). Methods : A total of 200 patients with the diagnosis of IBS, referred to the Shariati hospital in 2018, were enrolled using a correlational design and convenience sampling. All participants were asked to complete the ambiguity tolerance questionnaire, the life event checklist, and the personal concerns inventory...
October 2022: Middle East Journal of Digestive Diseases
#28
JOURNAL ARTICLE
Sivash Nikkholgh, Ivan M Pchelin, Ali Zarei Mahmoudabadi, Mahbubeh Shabanzadeh-Bardar, Maral Gharaghani, Aghil Sharifzadeh, Mohammadreza Mokhtari Hooyeh, Rasoul Mohammadi, Sadegh Nouripour-Sisakht, Farzad Katiraee, Ali Rezaei-Matehkolaei
Human infections by Trichophyton mentagrophytes occur mainly due to contact with diseased animals. In Iran, T. mentagrophytes genotype V is the most prevalent variant of the fungus. We aimed to determine the animal reservoir of T. mentagrophytes genotype V infection. The study was done on a total of 577 dermatophyte strains obtained from animals with signs of dermatophytosis and human patients. The list of extensively sampled animals included sheep, cows, cats and dogs. For human cases, epidemiological data were collected...
July 6, 2023: Medical Mycology
#29
JOURNAL ARTICLE
Pooria Ahmadi, Arian Afzalian, Arash Jalali, Saeed Sadeghian, Farzad Masoudkabir, Alireza Oraii, Aryan Ayati, Sepehr Nayebirad, Parmida Sadat Pezeshki, Masoumeh Lotfi Tokaldani, Akbar Shafiee, Mohammad Mohammadi, Elham Sanei, Masih Tajdini, Kaveh Hosseini
BACKGROUND: Although several studies are available regarding baseline Electrocardiographic (ECG) parameters and major and minor ECG abnormalities, there is considerable controversy regarding their age and gender differences in the literature. METHODS: Data from 7630 adults aged ≥ 35 from the Tehran Cohort Study registered between March 2016 and March 2019 were collected. Basic ECG parameters values and abnormalities related to arrhythmia, defined according to the American Heart Association definitions, were analyzed and compared between genders and four distinct age groups...
June 16, 2023: BMC Cardiovascular Disorders
#30
JOURNAL ARTICLE
Farzad Mohammadi, Amrita Dikpati, Nicolas Bertrand, Iwona Rudkowska
Studies have reported the potential benefits of consuming conjugated linoleic acid (CLA) and ruminant trans fatty acids (R-TFAs) in reducing the risk factors of metabolic syndrome (MetS). In addition, encapsulation of CLA and R-TFAs may improve their oral delivery and further decrease the risk factors of MetS. The objectives of this review were (1) to discuss the advantages of encapsulation; (2) to compare the materials and techniques used for encapsulating CLA and R-TFAs; and (3) to review the effects of encapsulated vs non-encapsulated CLA and R-TFAs on MetS risk factors...
May 23, 2023: Nutrition Reviews
#31
JOURNAL ARTICLE
Farzad Mohammadi, Miranda Green, Emma Tolsdorf, Karine Greffard, Mickael Leclercq, Jean-François Bilodeau, Arnaud Droit, Jane Foster, Nicolas Bertrand, Iwona Rudkowska
Industrially originated trans-fatty acids (I- t FAs), such as elaidic acid (EA), and ruminant trans-fatty acids (R- t FAs), such as trans -palmitoleic acid (TPA), may have opposite effects on metabolic health. The objective was to compare the effects of consuming 2-3% I- t FA or R- t FA on the gut microbiome and fecal metabolite profile in mice after 7 and 28 days. Forty C57BL/6 mice were assigned to one of the four prepared formulations: lecithin nanovesicles, lecithin nanovesicles with EA or TPA, or water...
March 16, 2023: Nutrients
#32
REVIEW
Farzad Pourghazi, Sammy Mohammadi, Maysa Eslami, Mojtaba Yousefi Zoshk, Sara Asadi, Hanieh-Sadat Ejtahed, Mostafa Qorbani
Childhood obesity is considered one of the important risk factors for many long-term morbidities. However, the long-term consequences of childhood obesity on kidney function are largely unknown. In this systematic review, all prospective or retrospective cohort studies and nested case-control articles which investigated association of childhood obesity with later life kidney function were searched via some international databases including PubMed, Scopus, Web of Science and Google Scholar. After screening 6,843 published articles, 8 prospective cohorts studies were included in the qualitative synthesis...
July 2023: Journal of Renal Nutrition
#33
REVIEW
Seyed Behnam Jazayeri, Seyed Farzad Maroufi, Esmaeil Mohammadi, Mohammad Amin Dabbagh Ohadi, Ellen-Merete Hagen, Maryam Chalangari, Seyed Behzad Jazayeri, Mahdi Safdarian, Shayan Abdollah Zadegan, Zahra Ghodsi, Vafa Rahimi-Movaghar
OBJECTIVES: This review was designed to update our earlier systematic review which evaluated both published and unpublished evidence on the incidence of traumatic spinal cord injury (TSCI) worldwide. METHODS: We used various search methods including strategic searching, reference checking, searching for grey literature, contacting registries, authors, and organizations requesting unpublished data, browsing related websites, and hand searching key journals. The quality of included studies was evaluated by Joanna Briggs Institute Critical Appraisal Tools...
April 2023: World neurosurgery: X
#34
JOURNAL ARTICLE
Abazar Pournajaf, Mehrdad Halaji, Farzin Sadeghi, Mohammad Chehrazi, Mostafa Javanian, Masoumeh Bayani, Mahmoud Sadeghi Haddad Zavareh, Mehran Shokri, Mohsen Mohammadi, Iraj Jafaripour, Roghayeh Pourkia, Mehrdad Saravi, Kamyar Amin, Naghmeh Zieaie Amiri, Mohammad Taghi Hedayati Goudarzi, Farzad Jalali, Yousef Yahyapour
BACKGROUND: In this retrospective study, we investigated the outcomes and demographic characteristics of COVID-19 patients with and without a history of CVD. METHODS: This large retrospective, multicenter study was performed on inpatients with suspected COVID-19 pneumonia who were admitted across four hospitals in Babol, Northern Iran.Demographic data, clinical data, and cycle threshold value (Ct) results of Real Time PCR were obtained. Then, participants were divided into two groups: (1) cases with CVDs, (2) cases without CVDs...
January 2023: Ethiopian Journal of Health Sciences
#35
Mohammad Abolhosseini, Zahra Khorrami, Sare Safi, Mohammad Esmaeil Akbari, Seyed Mohamadmehdi Moshtaghion, Seyed Farzad Mohammadi, Mozhgan Rezaei Kanavi, Saeed Karimi
No abstract text is available yet for this article.
February 14, 2023: Scientific Reports
#36
JOURNAL ARTICLE
Vahid Mansouri, Morteza Heidari, Maryam Bemanalizadeh, Reza Azizimalamiri, Shahriar Nafissi, Masood Ghahvechi Akbari, Mohammad Barzegar, Ali Reza Moayedi, Reza Shervin Badv, Mahmood Mohamadi, Ali Reza Tavasoli, Susan Amirsalari, Ali Khajeh, Soroor Inaloo, Farzad Fatehi, Sareh Hosseinpour, Meisam Babaei, Seyed Ahmad Hosseini, Seyyed Mohammad Mahdi Hosseiny, Afshin Fayyazi, Firoozeh Hosseini, Mehran Beiraghi Toosi, Nahid Khosroshahi, Homa Ghabeli, Habibeh Nejad Biglari, Simin Khayatzadeh Kakhki, Seyed Hossein Mirlohi, Elham Bidabadi, Bahram Mohammadi, Abdolmajid Omrani, Mostafa Sedighi, Mohammad Vafaee-Shahi, Maryam Rasulinezhad, Seyyed Mohamad Hoseini, Mojtaba Movahedinia, Zahra Rezaei, Parviz Karimi, Hossein Farshadmoghadam, Saeed Anvari, Omid Yaghini, Jafar Nasiri, Gholamreza Zamani, Mahmoud Reza Ashrafi
BACKGROUND: insufficient amounts of survival motor neuron protein is leading to one of the most disabling neuromuscular diseases, spinal muscular atrophy (SMA). Before the current study, the detailed characteristics of Iranian patients with SMA had not been determined. OBJECTIVE: To describe the key demographic, clinical, and genetic characteristics of patients with SMA registered in the Iranian Registry of SMA (IRSMA). METHODS: IRSMA has been established since 2018, and the demographic, clinical, and genetic characteristics of patients with SMA were recorded according to the methods of treat neuromuscular disease (TREAT-NMD) project...
February 6, 2023: Journal of Neuromuscular Diseases
#37
JOURNAL ARTICLE
Farzad Mohammadi, Nicolas Bertrand, Iwona Rudkowska
Two distinct types of trans fatty acids (TFA) are found in the diet. Industrial TFA such as elaidic acid (EA) have deleterious effects on metabolic risk factors, and oppositely ruminant TFA including trans-palmitoleic acid (TPA) may have beneficial effects. The objective is to evaluate the taste preference between EA, TPA, lecithin or water. In this study, 24 female C57BL/6 mice were microchipped and placed in two separate IntelliCages® . Nano encapsulated TFA or lecithin were added to drinking water in different corners of the cage with normal diet...
January 24, 2023: Nutrients
#38
JOURNAL ARTICLE
Mohammad Abolhosseini, Zahra Khorrami, Sare Safi, Mohammad Esmaeil Akbari, Seyed Mohamadmehdi Moshtaghion, Seyed Farzad Mohammadi, Saeed Karimi, Mozhgan Rezaei Kanavi
Investigating secular trends of ocular cancer registration in Iran. After acquiring Iranian national population-based cancer registry data, trends of age-standardised incidence rates (ASIR) of ocular cancers and annual percent changes (APC) between 2004 and 2016 were analysed in age groups, gender, topography and morphology types with joinpoint regression analysis. Age, period, and cohort effects on incidence rates were estimated by age-period-cohort model. Geographic distribution of ASIR was assessed using GIS...
January 19, 2023: Scientific Reports
#39
JOURNAL ARTICLE
Mahdi Mahdavi, Sahar Saeedi Moghaddam, Mohsen Abbasi-Kangevari, Esmaeil Mohammadi, Parnian Shobeiri, Guive Sharifi, Ali Jafari, Negar Rezaei, Narges Ebrahimi, Nazila Rezaei, Seyyed-Hadi Ghamari, Mohammad-Reza Malekpour, Majid Khalili, Bagher Larijani, Farzad Kompani
INTRODUCTION: Central nervous system cancers (CNS cancers) impose a significant burden upon healthcare systems worldwide. Currently, the lack of a comprehensive study to assess various epidemiological indexes of CNS cancers on national and subnational scales in Iran can hamper healthcare planning and resource allocation in this regard. This study aims to fill this gap by providing estimates of CNS cancer epidemiological measures on national and subnational levels in Iran from 1990 to 2019...
January 9, 2023: Cancer Medicine
#40
JOURNAL ARTICLE
Esmaeil Mohammadi, Sahar Saeedi Moghaddam, Sina Azadnajafabad, Seyed Farzad Maroufi, Mohammad-Mahdi Rashidi, Mohammadreza Naderian, Ali Jafari, Guive Sharifi, Erfan Ghasemi, Nazila Rezaei, Mohammad-Reza Malekpour, Farzad Kompani, Negar Rezaei, Bagher Larijani, Farshad Farzadfar
BACKGROUND: This study presents estimates of central nervous system (CNS) cancers' prevalence, incidence and its contributors, death, years-of-life-lost (YLLs), years-lived-with-disability (YLDs), and disability-adjusted-life years (DALYs) from 1990 to 2019 in North Africa and the Middle East. METHODS: Primary measures were retrieved from Global Burden of Disease 2019. The contribution of various factors to the observed incidence and mortality changes was investigated with decomposition and age-period-cohort analyses...
December 28, 2022: World Neurosurgery
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