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Eri Nitta, Kazuyuki Hirooka, Takeru Shimazaki, Shino Sato, Kaori Ukegawa, Yuki Nakano, Akitaka Tsujikawa
PURPOSE: This study compared retinal vessel oxygen saturation before and after glaucoma surgery. METHODS: Retinal oxygen saturation in glaucoma patients was measured using a non-invasive spectrophotometric retinal oximeter. Adequate image quality was found in 49 of the 108 consecutive glaucoma patients recruited, with 30 undergoing trabeculectomy, 11 EX-PRESS and eight trabeculotomy. Retinal oxygen saturation measurements in the retinal arterioles and venules were performed at 1 day prior to and at approximately 10 days after surgery...
October 24, 2016: Acta Ophthalmologica
Vujica Markovic, Dragan Vukovic, Aleksandra Radosavljevic, Ivan Marjanovic
PURPOSE: To investigate the possible association between acquired ectropion uveae and blunt trauma to the eye. We present 3 cases of acquired ectropion uveae that occurred after blunt trauma to the eye. There are no previously published data on possible association of these conditions. METHODS: A retrospective review was conducted of patients with ectropion uveae and eye injury at University Eye Hospital over a 10-year period (2006-2016). We analyzed medical records and clinical findings...
October 21, 2016: European Journal of Ophthalmology
Jong Chul Han, Young Hoon Hwang, Byung Heon Ahn
PURPOSE: To evaluate the safety and efficacy of a novel membrane-tube (MT)-type glaucoma shunt device for refractory glaucoma surgery. The device consists of an expanded polytetrafluoroethylene membranous reservoir, as well as a silicone tube (300-μm external and 200-μm internal diameter) with an intraluminal stent. We named the device "Finetube MT". METHODS: The Finetube MT was implanted into 44 glaucomatous eyes that had insufficient intraocular pressure (IOP) control despite medical treatment or previous trabeculectomy...
October 20, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Young Cheong Kim, Mi Sun Sung, Hwan Heo, Sang Woo Park
BACKGROUND: To compare refractive outcomes after cataract surgery between patients with closed-angle and open-angle glaucoma and evaluate the influence of preoperative factors on refractive outcomes in patients with glaucoma. METHODS: Patients diagnosed with glaucoma and who underwent uncomplicated cataract surgery were enrolled in this retrospective observational study. We collected data including age, history of prior laser peripheral iridotomy and trabeculectomy, type of glaucoma, manifest refraction, intraocular pressure, axial length, and various anterior segment parameters using anterior-segment optical coherence tomography...
October 18, 2016: BMC Ophthalmology
Joann J Kang, David C Ritterband, Kevin Lai, Jeffrey M Liebmann, John A Seedor
PURPOSE: To evaluate visual outcomes and complications after Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with previous glaucoma surgery. METHODS: A retrospective chart review was conducted of 129 procedures in 102 eyes of 96 patients who underwent DSAEK and previous glaucoma surgery at New York Eye and Ear Infirmary of Mt Sinai. The mean length of follow-up was 29.1 ± 25.5 months. Patients with postoperative follow-up duration of less than 3 months were excluded from analysis...
October 14, 2016: Cornea
Davinder S Grover, David G Godfrey, Oluwatosin Smith, Wei Shi, William J Feuer, Ronald L Fellman
PURPOSE: To report on outcomes of gonioscopy-assisted transluminal trabeculotomy (GATT) in eyes with prior incisional glaucoma surgery. PATIENTS AND METHODS: A retrospective review was performed for all patients who underwent a GATT procedure with a history of prior incisional glaucoma surgery. RESULTS: Thirty-five eyes of 35 patients were treated. The mean age was 67.7 years. Nineteen eyes had a prior trabeculectomy, 13 eyes had a prior glaucoma drainage device, 4 eyes had a prior trabectome, and 5 eyes had prior endocyclophotocoagulation...
October 6, 2016: Journal of Glaucoma
A G M Jünemann, R Rejdak, B Hohberger
BACKGROUND: In contrast to all other glaucoma surgeries, filtration surgery is associated with biomicroscopically visible wound healing, which enables the surgeon to perform revision surgeries if necessary. OBJECTIVES: The aim of this review is to provide general considerations and to give a structured overview about bleb revisions after trabeculectomy. MATERIALS AND METHODS: The different revision techniques are explained in detail and in the context of perioperative management...
October 13, 2016: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
Fatima Kyari, Winifred Nolan, Clare Gilbert
PURPOSE OF THE STUDY: Glaucoma, a chronic non-communicable disease, and leading cause of irreversible blindness worldwide is a public health problem in Nigeria, with a prevalence of 5.02% in people aged ≥40 years. The purpose of this nationwide survey was to assess Nigerian ophthalmologists' practice patterns and their constraints in managing glaucoma. STUDY DESIGN: Ophthalmologists were sent a semistructured questionnaire on how they manage glaucoma, their training in glaucoma care, where they practice, their access to equipment for diagnosis and treatment, whether they use protocols and the challenges they face in managing patients with glaucoma...
October 11, 2016: BMJ Open
Ignacio Rodriguez-Una, Augusto Azuara-Blanco, Anthony J King
BACKGROUND: To evaluate the spectrum of glaucoma surgery and the post-operative follow-up regimes undertaken among glaucoma specialists in the United Kingdom. DESIGN: National survey. PARTICIPANTS: Seventy-five glaucoma specialists (consultants and fellows). METHODS: An eight-question survey was emailed to all glaucoma subspecialists members of the United Kingdom and Eire Glaucoma Society. MAIN OUTCOME MEASURES: Surgery undertaken, post-operative management, awareness of intervention tariff and handling of the follow-up burden generated through surgery...
October 11, 2016: Clinical & Experimental Ophthalmology
Kristine Baumane, Renate Ranka, Guna Laganovska
PURPOSE: The aim of this study is to determine differences in the levels of NT-proANP in the plasma and aqueous humor of glaucoma and cataract patients and to evaluate whether any relationships are present. METHODS: The study group consisted of 58 patients with primary-open glaucoma (POAG) undergoing trabeculectomy surgery. The control group was comprised of 32 age-matched cataract patients. The concentration of the N-terminal fragment of the proatrial natriuretic peptide (NT-proANP, 1-98) in the aqueous humor and blood plasma samples was measured using an immunochemical method (ELISA)...
October 10, 2016: Current Eye Research
Ping-Bo Ou-Yang, Xin Qi, Xuan-Chu Duan
BACKGROUND: The giant filtering bleb encroaching onto the corneal surface is a rare occurrence in our and other's clinical experience (Kapoor and Syed, Int. Ophthalmol 31(5):403-404, 2011), even in patients having had a trabeculectomy with mitomycin C, and how it developed is debated. In this paper, we report a patient who developed a huge overhanging filtering bleb after trabeculectomy, and present our intraoperative photographs, histopathology and immunohistochemistry results. CASE PRESENTATION: A 62-year-old female visited our hospital due to the giant filtering bleb encroaching onto the corneal surface which was about 6 mm × 8 mm × 3 mm...
October 6, 2016: BMC Ophthalmology
Dawei Lei, Changgui Dong, William Ka Kei Wu, Aimeng Dong, Tingting Li, Matthew T V Chan, Xinrong Zhou, Huiping Yuan
Purposes: Trabeculectomy is a surgical procedure for lowering intraocular pressure in glaucoma patients, in which excessive scarring leading to failure of the filtering bleb adversely affects the surgical outcome. Heightened Tenon's capsule fibroblast (TCF) proliferation and extracellular matrix (ECM) deposition are implicated in this process but endogenous factors that regulate TCF functions remain largely elusive. This study sought to elucidate the role of connective tissue growth factor (CTGF) in the regulation of TCF phenotypes and signaling...
October 1, 2016: Investigative Ophthalmology & Visual Science
Munemitsu Yoshikawa, Tadamichi Akagi, Hideo Nakanishi, Hanako Ohashi Ikeda, Satoshi Morooka, Hiroshi Yamada, Tomoko Hasegawa, Yuto Iida, Nagahisa Yoshimura
PURPOSE: To investigate longitudinal changes in intraocular pressure (IOP), axial length (AL), and choroidal thickness (ChT) in primary open-angle glaucoma (POAG) eyes after trabeculectomy and to evaluate the parameters that might influence those changes. METHODS: In this prospective observational study, we recruited 28 patients with POAG (28 eyes) scheduled for trabeculectomy. The average macular ChTs and foveal retinal thicknesses along 6-mm segments centered on the fovea were examined preoperatively and postoperatively (at 1, 3, and 6 months) using swept-source optical coherence tomography...
October 3, 2016: Japanese Journal of Ophthalmology
Bo Li, Feng-Yun Wang, Tai-Liang Lv, Yu Zhu
The aim of the present study was to examine the effects of phacoemulsification and intraocular lens implantation combined with ciliarotomy in the treatment of angle-closure glaucoma with cataract in the elderly. A total of 68 patients were consecutively selected and divided into the control group with 33 cases (48 eyes) and the observation group with 35 cases (53 eyes). Cataract surgery combined with trabeculectomy was performed on the patients in the control group and phacoemulsification cataract extraction combined with ciliarotomy was performed on the subjects in the observation group, to compare postoperative effects and complications...
October 2016: Experimental and Therapeutic Medicine
Mohammad Pakravan, Azam Alvani, Hamed Esfandiari, Elham Ghahari, Mehdi Yaseri
Trabeculectomy is the most common surgical procedure for the management of glaucoma, which may significantly influence ocular biometry. Axial length and anterior chamber depth tend to decrease, while crystalline lens and choroidal thickness increase post-operatively. An increase in with-the-rule astigmatism is also observed after the procedure. Such biometric changes affect intraocular lens power calculation even years after the procedure. Non-contact biometric methods and postponing cataract surgery after trabeculectomy could reduce calculation errors associated with surgically induced alterations in ocular biometrics...
September 29, 2016: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Farihah Anwar, Angela Turalba
BACKGROUND: Glaucoma is the second leading cause of blindness in the world. Angle closure glaucoma accounts for 25% of all glaucoma, with Asia having the highest rate. Angle closure is an anatomical variation, making the Inuit, Chinese, and other Asians more susceptible. Current treatments include medical, laser, and surgical modalities. PURPOSE: To identify the current treatment protocols for primary angle closure. DISCUSSION: The current general protocol to treat angle closure is to lower the intraocular pressure with medications and perform laser iridotomy...
September 29, 2016: Seminars in Ophthalmology
Oliver L Yeh, Karine D Bojikian, Mark A Slabaugh, Philip P Chen
PURPOSE: To examine refractive outcomes after phacoemulsification in eyes with prior trabeculectomy. DESIGN: Retrospective observational case-control study METHODS:: Comparison of eyes of glaucoma patients undergoing cataract surgery after trabeculectomy (study group) with a matched group with medically controlled glaucoma (control group). Laser interferometry was used to obtain ocular biometry. We measured the difference between the expected and actual postoperative refraction using third-generation and fourth-generation intraocular lens (IOL) prediction formulae (Haigis, Holladay 2, Hoffer Q, and SRK-T)...
September 21, 2016: Journal of Glaucoma
Matthew D Benson, Imran Jivraj, Karim F Damji, Carlos E Solarte
PURPOSE: To report a rare case of congenital glaucoma in a patient with CHARGE syndrome, present gonioscopic photographs, and explore mechanisms of disease that may account for this association. PATIENTS AND METHODS: We describe a 35-week-old girl with previously diagnosed CHARGE syndrome who presented with corneal edema, buphthalmos, and elevated intraocular pressure in the left eye. She was subsequently diagnosed with congenital glaucoma and started on topical and oral therapy...
September 21, 2016: Journal of Glaucoma
Claudio I Perez, Felipe Mellado, Alex Jones, Ricardo Colvin
PURPOSE OF THE STUDY: The purpose of the study was to report and evaluate outcomes of trabeculectomy with use of a subconjunctival biodegradable collagen matrix implant. PATIENTS AND METHODS: Retrospective review of trabeculectomy with Ologen implant of 65 eyes of 58 patients by the same surgeon from October, 2011 to October, 2014. Exclusion criteria were <6 months of follow-up after surgery, and uveitic or neovascular glaucoma. Demographic characteristics of the study population, visual acuity, intraocular pressure (IOP), glaucoma medications, bleb characteristics, and early and late postoperative complications were recorded...
September 21, 2016: Journal of Glaucoma
Eman M Elhefney, Hossam T Al-Sharkawy, Hanem M Kishk, Hossam Abouelkheir
PURPOSE: To evaluate the preliminary results of biodegradable collagen matrix implant (Ologen) designed to improve outcome in patients with infantile glaucoma undergoing combined trabeculotomy and trabeculectomy. METHODS: A biodegradable collagen matrix (OculusGen) was placed in the subconjunctival space, partially over the scleral flap and the sclera in 20 eyes of 11 patients with infantile glaucoma who underwent combined trabeculotomy and trabeculectomy. Patients were examined preoperatively and on the first postoperative day with multiple postoperative follow-up visits within 12 months after surgery...
September 7, 2016: European Journal of Ophthalmology
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