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Trabeculectomy

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https://www.readbyqxmd.com/read/28104418/five-year-pooled-data-analysis-of-the-ahmed-baerveldt-comparison-study-and-the-ahmed-versus-baerveldt-study
#1
Panos G Christakis, Dongyu Zhang, Donald L Budenz, Keith Barton, James C Tsai, Iqbal I K Ahmed
PURPOSE: To determine the relative efficacy of the Ahmed-FP7 and Baerveldt BG101-350 implants. DESIGN: Pooled analysis of two multicenter, randomized, clinical trials. METHODS: 514 patients aged 18 or older with uncontrolled glaucoma that had failed, or were at high risk of failing trabeculectomy were randomized to receive an Ahmed implant (n=267) or Baerveldt implant (n=247). Cumulative failure rates (using an intraocular pressure (IOP) target of 6-18 mmHg inclusive), de novo glaucoma surgery rates, mean IOP, mean glaucoma medication use, and visual acuity were compared...
January 16, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28100482/mitomycin-c-augmented-trabeculectomy-subtenon-injection-versus-soaked-sponges-a-randomised-clinical-trial
#2
Mohammad Pakravan, Hamed Esfandiari, Shahin Yazdani, Azadeh Douzandeh, Nassim Amouhashemi, Mehdi Yaseri, Parto Pakravan
BACKGROUND/AIMS: To compare the efficacy and safety of subtenon injection of mitomycin C (MMC) with that of conventional application of MMC-soaked sponges in trabeculectomy. METHODS: In this multicentre randomised clinical trial, 80 consecutive open-angle glaucoma cases were randomised into two groups; group 1 received a subtenon injection of 0.1 mL of 0.01% MMC, while group 2 received 0.02% MMC-soaked sponges. Primary outcome measure was intraocular pressure (IOP), and secondary outcome measures were endothelial cell count (ECC) changes and bleb morphology according to the Indiana Bleb Appearance Grading Scale...
January 18, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28079683/factors-associated-with-graft-detachment-after-primary-descemet-stripping-automated-endothelial-keratoplasty
#3
Yoav Nahum, Pia Leon, Michael Mimouni, Massimo Busin
PURPOSE: To identify risk factors associated with postoperative graft detachment after Descemet stripping automated endothelial keratoplasty (DSAEK). METHODS: In this retrospective institutional cohort study, the study group included all consecutive eyes that underwent primary DSAEK between January 2005 and October 2015 at Villa Serena-Villa Igea private hospitals (Forlì, Italy) and developed postoperative graft detachment (n = 45). The control group included all eyes that underwent primary DSAEK during the same period and did not develop graft detachment (n = 1167)...
January 11, 2017: Cornea
https://www.readbyqxmd.com/read/28058152/the-effect-of-adjuvant-intracameral-triamcinolone-acetonide-on-the-surgical-results-of-trabeculectomy-with-mitomycin-c
#4
Neşe Alagöz, Cengiz Alagöz, Yusuf Yıldırım, Ceren Yeşilkaya, Çiğdem Altan, Ercüment Bozkurt, Banu Şatana, Berna Başarır, Muhittin Taşkapılı
OBJECTIVES: To evaluate the effect of adjuvant intracameral triamcinolone acetonide (TA) on the surgical results of trabeculectomy with mitomycin C. MATERIALS AND METHODS: All consecutive trabeculectomy cases performed in the glaucoma clinic between July 2012 and December 2013 were retrospectively reviewed from the patient charts. Only those with follow-up of 12 months or longer were included. Patients with intraoperative intracameral TA (study group, n=19) were compared to those without TA (control group, n=21) in terms of surgical success, intraocular pressure (IOP) change, medication use and complications...
August 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28056057/flat-anterior-chamber-after-trabeculectomy-in-secondary-angle-closure-glaucoma-with-best1-gene-mutation-case-series
#5
Yimin Zhong, Xinxing Guo, Hui Xiao, Jingyi Luo, Chengguo Zuo, Xiaobo Huang, Jingjing Huang, Lan Mi, Qingjiong Zhang, Xing Liu
PURPOSE: Trabeculectomy has been regarded as a mainstay of initial treatment in eyes of angle closure glaucoma (ACG) with peripheral anterior synechia > 180° in the Chinese population while its efficacy in secondary ACG with BEST1 gene mutation remains unclear. We set out to investigate the treatment outcome of trabeculectomy for secondary ACG in a group of patients with autosomal recessive bestrophinopathy (ARB). METHODS: In this retrospective case series study, 8 secondary ACG patients with ARB and their 4 recruited family members underwent a thorough ophthalmic examination including best-corrected visual acuity, Goldmann applanation tonometry, gonioscopy, and fundus examinations...
2017: PloS One
https://www.readbyqxmd.com/read/28038923/charles-bonnet-syndrome-in-a-child-with-congenital-glaucoma
#6
E Santos-Bueso, M Serrador-García, F Sáenz-Francés, C Méndez-Hernández, L Morales-Fernández, J M Martínez-de-la-Casa, J García-Feijoo, J Porta-Etessam
CASE REPORT: The case is presented of a 12 year-old boy with congenital glaucoma and low visual acuity diagnosed with Charles Bonnet syndrome. This consisted of the acute onset of complex, repetitive, persistent, and with visual hallucinations (people, brooms and coffeemakers) of self-limited evolution without treatment. The patient was diagnosed with congenital glaucoma at 3 years of age, and subjected to a trabeculectomy in right eye, and trabeculectomy and keratoplasty in his left eye...
December 27, 2016: Archivos de la Sociedad Española de Oftalmología
https://www.readbyqxmd.com/read/28034308/collagen-matrix-vs-mitomycin-c-in-trabeculectomy-and-combined-phacoemulsification-and-trabeculectomy-a-randomized-controlled-trial
#7
Angelo P Tanna, Alfred W Rademaker, C Gustavo de Moraes, David G Godfrey, Steven R Sarkisian, Steven D Vold, Robert Ritch
BACKGROUND: Antifibrotic agents are commonly utilized to enhance the success rates of trabeculectomy. Novel approaches to further improve success rates and reduce the risks of complications are needed. The purpose of this study was to compare intraocular pressure (IOP)-lowering efficacy and safety of trabeculectomy or combined phacoemulsification and trabeculectomy with mitomycin-C (MMC) vs. Collagen Matrix (CM). METHODS: A prospective, multicenter, randomized controlled trial was performed...
December 29, 2016: BMC Ophthalmology
https://www.readbyqxmd.com/read/28030611/silibinin-inhibits-platelet-derived-growth-factor-driven-cell-proliferation-via-downregulation-of-n-glycosylation-in-human-tenon-s-fibroblasts-in-a-proteasome-dependent-manner
#8
Yi-Hao Chen, Ching-Long Chen, Da-Wen Lu, Chang-Min Liang, Ming-Cheng Tai, Jiann-Torng Chen
The objective of this study was to evaluate the effects of silibinin on cell proliferation in platelet-derived growth factor (PDGF)-treated human Tenon's fibroblasts (HTFs). The effect of silibinin on cell proliferation in PDGF-treated HTFs was determined by examining the expression of proliferating cell nuclear antigen (PCNA) and performing WST-1 assays. Cell cycle progression was evaluated using flow cytometry. The related cyclins and cyclin-dependent kinases (CDKs) were also analyzed using western blot. A modified rat trabeculectomy model was established to evaluate the effect of silibinin on cell proliferation in vivo...
2016: PloS One
https://www.readbyqxmd.com/read/28003985/comparison-of-canaloplasty-and-trabeculectomy-for-open-angle-glaucoma-a-meta-analysis
#9
Zhong-Jing Lin, Shuo Xu, Shou-Yue Huang, Xiao-Bin Zhang, Yi-Sheng Zhong
AIM: To evaluate the advantage of canaloplasty compared to trabeculectomy for patients with open angle glaucoma. METHODS: Potentially relevant studies were systematically searched using various databases from inception until December 2015. The outcome analyses performed automatically using Revman 5.3 included intraocular pressure reduction (IOPR), postoperative success rate, anti-glaucoma medications reduction and the incidence of adverse events. RESULTS: We included four qualified studies incorporating a total of 215 eyes for quantitative synthesis...
2016: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28002194/spontaneous-dislocation-of-trabeculectomy-scleral-flap-in-the-anterior-chamber-in-a-patient-with-pseudoxanthoma-elasticum
#10
Lina Danieliute, Myrto Tsagkataki, Eleni Nikita
We report a case of a 54-year-old man, known to have pseudoxanthoma elasticum (PXE), who had a trabeculectomy in his left eye for secondary glaucoma following blunt trauma. Ten years after augmented trabeculectomy, the patient presented to casualty clinic with an inferiorly dislocated, anterior chamber (AC), scleral trabeculectomy flap. Corrected vision was hand movement with an intraocular pressure of 17 mm Hg. There was significant AC inflammation (cells 2+). Gonioscopy revealed a residual mobile scleral flap...
December 20, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/28002191/sekundo-s-applanator-5-years-of-experience-with-transconjunctival-suturing
#11
Hisham Elbaz, Walter Sekundo, Frank-Michael Schröder, Stephan Schulze
Sekundo's Applanator is a new surgical instrument used mainly in transconjunctival scleral flap suturing in cases of postoperative hypotony after trabeculectomy. In contrast to Hoskins lens, it offers better visualization of the border of the scleral flap with good intraoperative stabilization of the globe; thus, it increases the effectiveness and decreases the time of the surgical procedure. Sekundo's Applanator was also found to be useful in reducing the size of an oversized bleb after trabeculectomy and in the closure of leaking sutureless sclerotomies after vitrectomies...
December 20, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/28002187/early-reoperation-rate-complication-and-outcomes-in-resident-performed-glaucoma-surgery
#12
Yen C Hsia, Jun Hui Lee, Qi N Cui, Jay M Stewart, Ayman Naseri, Travis Porco, Robert L Stamper, Ying Han
PURPOSE OF THE STUDY: The purpose of the study was to examine reoperation rate and complications of resident-performed glaucoma surgeries within the first 90 postoperative days. MATERIALS AND METHODS: A retrospective study of resident-performed glaucoma filtering surgeries at the San Francisco Veterans Affairs Medical Center between 2002 and 2014 was performed. Patients requiring reoperation within 90 days of the initial surgery were included in our study. Combined surgeries were excluded...
December 20, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27994821/erratum-descemet-s-membrane-detachment-management-following-trabeculectomy
#13
(no author information available yet)
[This corrects the article on p. 323 in vol. 11, PMID: 27621793.].
October 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27994819/intraoperative-optical-coherence-tomography-guided-bleb-needling
#14
Tanuj Dada, Dewang Angmo, Neha Midha, Talvir Sidhu
Two patients with history of trabeculectomy presented with uncontrolled intraocular pressure (IOP) postoperatively. The first patient had a flat and vasularized bleb 10 weeks after the surgery, and the second subject developed encapsulated bleb 3 months postoperatively. Both patients were taken to the operating room and intraoperative optical coherence tomography (OCT) guided bleb needling was performed to restore aqueous egress into the subconjunctival space. Postoperatively, IOP of the operated eyes ranged 14-18 mmHg at week 6 and month 3...
October 2016: Journal of Ophthalmic & Vision Research
https://www.readbyqxmd.com/read/27980360/changes-in-corneal-endothelial-cell-after-ahmed-glaucoma-valve-implantation-and-trabeculectomy-1-year-follow-up
#15
Min Su Kim, Kyoung Nam Kim, Chang-Sik Kim
PURPOSE: To compare changes in corneal endothelial cell density (CECD) after Ahmed glaucoma valve (AGV) implantation and trabeculectomy. METHODS: Changes in corneal endothelium in patients that underwent AGV implantation or trabeculectomy were prospectively evaluated. Corneal specular microscopy was performed at the central cornea using a non-contact specular microscope before surgery and 6 months and 12 months after surgery. The CECD, hexagonality of the endothelial cells, and the coefficient of variation of the cell areas were compared between the two groups...
December 2016: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/27977478/corneal-biomechanical-changes-after-trabeculectomy-and-the-impact-on-intraocular-pressure-measurement
#16
Karin R Pillunat, Eberhard Spoerl, Naim Terai, Lutz E Pillunat
PURPOSE: To evaluate corneal biomechanical changes induced by trabeculectomy and their impact on intraocular pressure (IOP) measurements. MATERIALS AND METHODS: In total, 35 eyes of 35 consecutive glaucoma patients undergoing first-time trabeculectomy with mitomycin C were enrolled in this prospective interventional case series. Goldmann applanation tonometry (GAT) IOP, central corneal thickness, axial length, and Ocular Response Analyzer measurements [Goldmann-correlated IOP (IOPg), corneal-compensated IOP (IOPcc), corneal hysteresis (CH), and corneal resistance factor (CRF)] were assessed before and 6 months after uncomplicated trabeculectomy...
December 13, 2016: Journal of Glaucoma
https://www.readbyqxmd.com/read/27960582/ultrasound-biomicroscopy-in-pseudophakic-patients-with-unexplained-recurrent-hyphema-or-vitreous-hemorrhage
#17
Saba T Alniemi, Sejal R Amin, Luanne Sculley, Sophie J Bakri
PURPOSE: To describe IOL haptic with iris or ciliary body touch on ultrasound biomicroscopy (UBM) in pseudophakic patients with unexplained recurrent hyphema or vitreous hemorrhage. METHODS: Retrospective chart review of 10 patients who presented with unexplained recurrent hyphema and or vitreous hemorrhage. RESULTS: There were eight posterior chamber intraocular lenses (PCIOL) and two sulcus lenses. Four cases had a history of glaucoma; two cases which had a history of trabeculectomy were found to have some bridging vessels along the sclerostomy requiring argon laser gonioplasty...
December 14, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27960578/sutureless-scleral-tunnel-trabeculectomy-evaluation-of-feasibility-and-effectiveness-versus-conventional-trabeculectomy-for-management-of-primary-open-angle-glaucoma
#18
Hany A Khairy, Moataz F Elsawy, Khaled Said-Ahmed
PURPOSE: To evaluate the intraocular pressure-lowering effect of sutureless scleral tunnel trabeculectomy with Mitomycin-C (MMC) compared to the standard trabeculectomy with MMC in patients with primary open angle glaucoma (POAG). METHODS: This was a masked, randomized, controlled comparison trial involving 34 eyes of 34 patients with bilateral POAG. Patients were randomized to receive sutureless sclera flap trabeculectomy with MMC or conventional trabeculectomy with MMC...
December 14, 2016: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/27958205/revision-of-trabeculectomy-filtering-blebs-with-mitomycin-c-long-term-results
#19
Maria Tulidowicz-Bielak, Ewa Kosior-Jarecka, Tomasz Żarnowski
AIM: The aim of the study is to assess the outcomes of transconjunctival mitomycin C (MMC)-augmented revision in eyes with failed trabeculectomy. MATERIALS AND METHODS: This is a retrospective, noncomparative case series. One hundred and twenty-one eyes of 113 consecutive glaucoma patients with previously failed trabeculectomy who underwent transconjunctival revision with at least 12 months of follow-up were initially included in the study. The success was determined on the basis of intraocular pressure (IOP) alone...
November 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27957366/severe-corticosteroid-induced-ocular-hypertension-requiring-bilateral-trabeculectomies-in-a-patient-with-takayasu-s-arteritis
#20
Anna Maria Gruener, Pranev Sharma, Sally Ameen, Faisal Ahmed
We present a rare case of severe corticosteroid-induced ocular hypertension (OHT) after prolonged systemic corticosteroid use in a young woman with Takayasu's arteritis. As she did not sufficiently respond to ocular antihypertensive therapies, bilateral enhanced trabeculectomies were required to normalize her intraocular pressures. The systemic side effects of corticosteroids are well known, yet steroid-induced OHT and glaucoma remain silent causes of ocular morbidity. This case highlights the importance of IOP-monitoring in visually asymptomatic patients on systemic corticosteroids...
2016: Case Reports in Ophthalmological Medicine
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