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Trabeculectomy

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https://www.readbyqxmd.com/read/28221332/sustained-resolution-of-macular-retinoschisis-after-trabeculectomy-in-a-patient-with-progressive-glaucoma
#1
Rany Woo, Handan Akil, Nicole Koulisis, Lisa C Olmos de Koo, James C H Tan
PURPOSE: To evaluate the clinical characteristics of a patient with primary open-angle glaucoma in whom macular retinoschisis resolved completely after trabeculectomy consistently lowered intraocular pressure (IOP). METHODS: A single case report. RESULTS: We report a case of retinoschisis involving the macula in a patient with primary open-angle glaucoma in the absence of myopic maculopathy, optic nerve anomaly, or x-linked retinoschisis. The patient's glaucoma was associated with progressive visual field loss in the setting of IOP fluctuations related to posture...
February 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28221330/comparison-of-anterior-segment-optical-coherence-tomography-bleb-grading-moorfields-bleb-grading-system-and-intraocular-pressure-after-trabeculectomy
#2
Joanne C Wen, Sandra S Stinnett, Sanjay Asrani
PURPOSE: To compare a novel anterior segment optical coherence tomography (AS-OCT) bleb grading system with a clinical bleb grading system and both with intraocular pressure (IOP) following trabeculectomy surgery. MATERIALS AND METHODS: A novel AS-OCT grading system based on bleb size and internal reflectivity was developed. An imaging center was tasked with masked grading of AS-OCT images acquired by multiple surgical sites at postoperative week (POW) 2, postoperative month (POM) 4, 6, and 12, respectively...
February 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28210791/-comparison-of-trabeculectomy-and-canaloplasty-pressure-reducing-effect-and-postoperative-interventions-complications
#3
T Taruttis, E Chankiewitz, T Hammer
BACKGROUND: Trabeculectomy (TET) is still the most commonly performed surgical treatment in dealing with primary open angle glaucoma (POAG) worldwide. Canaloplasty (CP) as a nonpenetrating surgical procedure has recently become a new option to efficiently reduce intraocular pressure (IOP). OBJECTIVES: This study compared both surgical procedures concerning the efficacy in IOP reduction. Furthermore we compared IOP fluctuation, postoperative medication, visual acuity, astigmatism and postoperative interventions and complications...
February 16, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28199397/efficacy-and-safety-of-preoperative-iop-reduction-using-a-preservative-free-fixed-combination-of-dorzolamide-timolol-eye-drops-versus-oral-acetazolamide-and-dexamethasone-eye-drops-and-assessment-of-the-clinical-outcome-of-trabeculectomy-in-glaucoma
#4
Katrin Lorenz, Joanna Wasielica-Poslednik, Katharina Bell, Giulia Renieri, Alexander Keicher, Christian Ruckes, Norbert Pfeiffer, Hagen Thieme
INTRODUCTION: To demonstrate that preoperative treatment for 28 days with topical dorzolamide/timolol is non-inferior (Δ = 4 mm Hg) to oral acetazolamide and topical dexamethasone (standard therapy) in terms of intraocular pressure (IOP) reduction 3 and 6 months after trabeculectomy in glaucoma patients. MATERIALS AND METHODS: Sixty-two eyes undergoing trabeculectomy with mitomycin C were included in this monocentric prospective randomized controlled study. IOP change between baseline and 3 months post-op was defined as the primary efficacy variable...
2017: PloS One
https://www.readbyqxmd.com/read/28197740/characteristics-of-successful-filtering-blebs-at-1%C3%A2-year-after-trabeculectomy-using-swept-source-three-dimensional-anterior-segment-optical-coherence-tomography
#5
Akiko Narita, Yuki Morizane, Tomoe Miyake, Jiro Seguchi, Tetsuya Baba, Fumio Shiraga
PURPOSE: To identify the cross-sectional characteristics of filtering blebs associated with intraocular pressure (IOP) control at 1 year after trabeculectomy with a square scleral flap and a fornix-based conjunctival flap. METHODS: A retrospective consecutive case series study was conducted. Eighty-four eyes of 79 patients who had undergone primary trabeculectomy were included. Surgical success was defined as IOP ≤15 mmHg and a >20% reduction in IOP without glaucoma medication and without additional glaucoma surgery at 1 year after trabeculectomy...
February 14, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28188728/trabeculectomy-bleb-associated-infections
#6
REVIEW
M Reza Razeghinejad, Shane J Havens, L Jay Katz
Trabeculectomy with antimetabolites is the most commonly performed surgery worldwide for glaucoma patients with progressive optic nerve head injury and visual field loss despite maximum pharmacologic intraocular pressure (IOP) lowering therapy. Trabeculectomy bleb-associated infections (BAI) remain one of the most feared early and long-term complications of trabeculectomy surgery because of their poor prognosis and variable response to antimicrobial therapy. Several studies have evaluated how surgical technique, conjunctival incision location, comorbid ocular pathology, concurrent medication use, and bleb morphology affect the risk of BAI...
February 7, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28188405/success-rates-of-2-site-phacoemulsification-combined-with-fornix-based-trabeculectomy-using-mitomycin-c-for-primary-angle-closure-glaucoma-and-primary-open-angle-glaucoma-in-an-asian-population
#7
Victor Koh, David Chen, Cecilia Maria Aquino, Joel Aduan, Chelvin Sng, Loon Seng Chee, Paul Chew
PURPOSE: To determine the long-term outcomes of 2-site phacoemulsification combined with fornix-based trabeculectomy using mitomycin C (MMC) for primary angle-closure glaucoma (PACG) and primary open-angle glaucoma (POAG) in an Asian population. METHODS: We reviewed the records of all patients with POAG or PACG who underwent phacoemulsification with trabeculectomy using MMC from January 2008 through December 2010 in a tertiary ophthalmology unit in Singapore. The primary outcome measure was cumulative success rates defined as complete [intraocular pressure (IOP) <21, 18, 15 mmHg without medication] and qualified (IOP <21, 18, 15 mmHg with at least 1 medication) success...
February 10, 2017: Japanese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28187473/-imaging-of-the-intrascleral-aqueous-drainage-system-new-insights-for-glaucoma-surgery-targeting-the-trabecular-meshwork
#8
C van Oterendorp
Numerous new techniques in glaucoma surgery target the trabecular meshwork, which is considered to be the main site of aqueous outflow resistance. These approaches rely on a functioning aqueous drainage system distal to the site of surgery. Thus, the intrascleral aqueous outflow tract comprises Schlemm's canal, collector channels and aqueous veins and has become an object of increasing research interest. The intrascleral outflow tract contributes approximately 25-50 % to the total aqueous outflow resistance, but the outflow capacity differs greatly over the segments of the eye...
February 10, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28168047/suppression-of-human-tenon-fibroblast-cell-proliferation-by-lentivirus-mediated-vegf-small-hairpin-rna
#9
Zhongqiu Li, Wen Hua, Xuedong Li, Wei Wang
Purpose. The functions of vascular endothelial growth factor (VEGF) in scar formation after trabeculectomy were investigated in a human Tenon fibroblast cell line from glaucoma patients using lentivirus-mediated VEGF shRNA. Methods. Human Tenon fibroblast (HTF) cells were isolated from scar tissue of glaucoma patients during secondary surgery. Lentivirus-VEGF-shRNA was constructed and transfected into HTF cells. Subsequently, VEGF mRNA and protein expression were analyzed using quantitative RT-PCR and western blotting, respectively, and the effects of VEGF knockdown were analyzed...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28161049/quality-of-life-in-the-tube-versus-trabeculectomy-study
#10
Aachal Kotecha, William J Feuer, Keith Barton, Steven J Gedde
PURPOSE: To report the vision-specific quality of life (QoL) outcomes in the Tube Versus Trabeculectomy (TVT) Study. DESIGN: Multicenter randomized clinical trial METHODS: Setting: 17 clinical centers Study population: Patients 18 to 85 years of age with medically uncontrolled glaucoma who had previous cataract and/or glaucoma surgery. INTERVENTIONS: Tube shunt (350-mm(2) Baerveldt glaucoma implant) or trabeculectomy with MMC. MAIN OUTCOME MEASURES: Vision-specific QoL using the NEI VFQ-25 and estimation of minimally important differences (MID) were the main outcome measures...
February 1, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28151873/bimatoprost-induced-late-onset-choroidal-detachment-after-trabeculectomy-a-case-report-and-review-of-the-literature
#11
Shunsuke Nakakura, Asuka Noguchi, Hitoshi Tabuchi, Yoshiaki Kiuchi
BACKGROUND: Choroidal detachment (CD) is often observed at an early period particularly after trabeculectomy and glaucoma drainage implant surgery. However, topical antiglaucoma eye drop-induced CD is a rare complication. Here, we report a case of topical bimatoprost-induced late-onset CD after trabeculectomy and review the literature. CASE REPORT: A 74-year-old man who suffered from primary open-angle glaucoma underwent his initial trabeculectomy with mitomycin-C in the right eye...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28149777/ex-press-implantation-versus-trabeculectomy-in-chinese-patients-with-poag-fellow-eye-pilot-study
#12
Wei Wang, Min-Wen Zhou, Wen-Bin Huang, Xin-Bo Gao, Xiu-Lan Zhang
AIM: To compare the outcomes of Ex-PRESS implantation in one eye versus trabeculectomy with mitomycin C in the fellow eye in Chinese patients with primary open-angle glaucoma (POAG). METHODS: This was a prospective, non-randomized comparative study. Forty-eight eyes of 24 patients with bilateral POAG necessitating surgery were included and underwent Ex-PRESS implantation under the scleral flap in one eye and trabeculectomy in the other eye according to patients' choice...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28146443/developing-an-item-bank-to-measure-quality-of-life-in-individuals-with-glaucoma-and-the-results-of-the-interview-with-patients-the-effect-of-visual-function-visual-field-progression-rate-medical-and-surgical-treatments-on-quality-of-life
#13
Masato Matsuura, Kazunori Hirasawa, Hiroyo Hirasawa, Mieko Yanagisawa, Hiroshi Murata, Chihiro Mayama, Ryo Asaoka
PURPOSE: To construct a new item bank to measure quality of life (QOL) in glaucoma patients and to evaluate glaucoma patients' QOL using the item bank. METHODS: An item bank of questions was generated through a literature review of QOL instruments useful for glaucoma patients. Using this item bank, a cognitive survey was performed on 203 patients with glaucoma (112 males and 91 females, 61.9±11.9 y old; mean±SD). The results were then analyzed using the Rasch analysis, and the Rasch-derived disability scores were predicted using linear modelling and the following clinical parameters: age, mean total deviation (mTD) in superior and inferior visual field (mTDsup/mTDinf), mTD progression rate, better visual acuity, worse visual acuity, number of eye drops administered per day, number of trabeculectomy procedures experienced in both eyes...
February 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28146442/comparison-of-ex-press-shunt-and-trabeculectomy-with-mitomycin-c-in-congenital-and-juvenile-glaucoma
#14
David L Nash, Eric R Crouch, Earl R Crouch
PURPOSE: To compare efficacy and safety of EX-PRESS mini glaucoma shunt (Alcon) and trabeculectomy with mitomycin-C (MMC) in the management of pediatric glaucoma. METHODS: The authors retrospectively reviewed patients from a single pediatric ophthalmology practice with either congenital or juvenile glaucoma who underwent surgical treatment with either trabeculectomy or EX-PRESS shunt insertion with MMC. Postoperative intraocular pressure at 6, 18, and 36 months, medication requirements, visual acuities, postoperative interventions, complications, and noncompliance with medications or follow-up was reviewed...
February 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28137824/outcome-of-repeat-trabeculectomies-long-term-follow-up
#15
Ignacio Rodriguez-Una, Alan P Rotchford, Anthony J King
AIM: To assess medium-term to long-term outcomes of a cohort of repeat trabeculectomy augmented with mitomycin C (MMC). METHODS: A prospective evaluation of consecutive separate site repeat MMC-augmented trabeculectomies undertaken at a single institution between October 2000 and December 2012. Information regarding visual acuity (VA), intraocular pressure (IOP), visual field progression, postoperative interventions, surgery complications and success of surgery are presented...
January 30, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28134460/surgical-outcomes-of-trabeculectomy-and-glaucoma-drainage-implant-for-uveitic-glaucoma-and-relationship-with-uveitis-activity
#16
Hye Jin Kwon, Yu Xiang George Kong, Lingwei William Tao, Lyndell L Lim, Keith R Martin, Catherine Green, Jonathan Ruddle, Jonathan G Crowston
IMPORTANCE: This study provides ophthalmologists who manage uveitic glaucoma with important information on factors that can affect the success of surgical management of this challenging disease. BACKGROUND: This study examines surgical outcomes of trabeculectomy and glaucoma device implant (GDI) surgery for uveitic glaucoma, in particular the effect of uveitis activity on surgical outcomes. DESIGN: Retrospective chart review at a tertiary institution...
January 30, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/28118610/safety-and-efficacy-of-canaloplasty-versus-trabeculectomy-in-treatment-of-glaucoma
#17
Haifeng Liu, Haitao Zhang, Yanhua Li, Han Yu
We assess the efficacy and safety of canaloplasty and trabeculectomy for treatment of glaucoma. We searched the China National Knowledge Infrastructure, PubMed, Web of Science, and WanFang databases for potentially eligible studies. Pooled risk ratio (RR) with 95% confidence interval (CI) was calculated using random- or fixed-effect models if appropriate. Eight studies were included for meta-analysis. There was no difference in intraocular pressure at 6 months (WMD = 0.97, 95%CI: -0.48-2.41). Intraocular pressure in canaloplasty group 12 months after operation was higher than in trabeculectomy group (WMD = 1...
January 19, 2017: Oncotarget
https://www.readbyqxmd.com/read/28118203/evaluation-of-the-efficacy-and-safety-of-the-new-susanna-glaucoma-drainage-device-in-refractory-glaucomas-short-term-results
#18
Luis G Biteli, Tiago S Prata, Carolina P B Gracitelli, Fábio N Kanadani, Flávia Villas Boas, Marcelo Hatanaka, Augusto Paranhos Junior
PURPOSE: To assess the efficacy and safety of the new Susanna glaucoma drainage device (SGDD) in patients with neovascular and refractory glaucomas. MATERIALS AND METHODS: In this prospective study, patients with neovascular glaucoma or refractory glaucomas (defined as eyes with previous trabeculectomy failure) were enrolled. All eyes had to have intraocular pressure (IOP) above 21 mm Hg despite maximum tolerated topical medication, or recent documentation of anatomic and/or functional progression...
January 23, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/28104418/five-year-pooled-data-analysis-of-the-ahmed-baerveldt-comparison-study-and-the-ahmed-versus-baerveldt-study
#19
Panos G Christakis, Dongyu Zhang, Donald L Budenz, Keith Barton, James C Tsai, Iqbal I K Ahmed
PURPOSE: To determine the relative efficacy of the Ahmed-FP7 and Baerveldt BG101-350 implants. DESIGN: Pooled analysis of two multicenter, randomized, clinical trials. METHODS: 514 patients aged 18 or older with uncontrolled glaucoma that had failed, or were at high risk of failing trabeculectomy were randomized to receive an Ahmed implant (n=267) or Baerveldt implant (n=247). Cumulative failure rates (using an intraocular pressure (IOP) target of 6-18 mmHg inclusive), de novo glaucoma surgery rates, mean IOP, mean glaucoma medication use, and visual acuity were compared...
January 16, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28100482/mitomycin-c-augmented-trabeculectomy-subtenon-injection-versus-soaked-sponges-a-randomised-clinical-trial
#20
Mohammad Pakravan, Hamed Esfandiari, Shahin Yazdani, Azadeh Douzandeh, Nassim Amouhashemi, Mehdi Yaseri, Parto Pakravan
BACKGROUND/AIMS: To compare the efficacy and safety of subtenon injection of mitomycin C (MMC) with that of conventional application of MMC-soaked sponges in trabeculectomy. METHODS: In this multicentre randomised clinical trial, 80 consecutive open-angle glaucoma cases were randomised into two groups; group 1 received a subtenon injection of 0.1 mL of 0.01% MMC, while group 2 received 0.02% MMC-soaked sponges. Primary outcome measure was intraocular pressure (IOP), and secondary outcome measures were endothelial cell count (ECC) changes and bleb morphology according to the Indiana Bleb Appearance Grading Scale...
January 18, 2017: British Journal of Ophthalmology
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