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DOES THIS PATIENT HAVE MIGRAINE

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https://www.readbyqxmd.com/read/27634731/no-change-in-interictal-pacap-levels-in-peripheral-blood-in-women-with-chronic-migraine
#1
Eva Cernuda-Morollón, Nuria Riesco, Pablo Martínez-Camblor, Esther Serrano-Pertierra, Carmen García-Cabo, Julio Pascual
OBJECTIVE: To determine total pituitary adenylate cyclase activating polypeptide (PACAP) in peripheral blood as a potential marker of the activation of the parasympathetic arm of the trigemino-vascular system in chronic migraine (CM) in a case-control study. METHODS: Women older than 17 and diagnosed as CM were recruited. Healthy women with no headache history and women with episodic migraine (EM) served as control groups. Total PACAP and vasoactive intestinal peptide (VIP) levels were determined in blood samples obtained from the right antecubital vein by ELISA outside a migraine attack and having taken no symptomatic medication the day before...
October 2016: Headache
https://www.readbyqxmd.com/read/27441999/migraine-does-aura-require-investigation
#2
Nirosen Vijiaratnam, Daniel Barber, Kai Zheong Lim, Eldho Paul, Matthew Jiang, Benjamin Chosich, Tissa Wijeratne
OBJECTIVES: Migraine is a debilitating condition that affects approximately 15% of the general population. It represents a huge proportion of presentations to the emergency department and a significant number of neurology admissions. Patients are often investigated with imaging. This is particularly the case with migraine with aura (MA). The yield of imaging is however low. There is limited information on Australian hospital presentations and utility of imaging. We aimed to analyse the demographics of migraine presentations to our hospital and the yield of imaging in our centre to help guide future approaches to these patients...
September 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27322907/how-to-apply-the-ahs-evidence-assessment-of-the-acute-treatment-of-migraine-in-adults-to-your-patient-with-migraine
#3
Tamara Pringsheim, William Jeptha Davenport, Michael J Marmura, Todd J Schwedt, Stephen Silberstein
The "Acute Treatment of Migraine in Adults: The American Headache Society Evidence Assessment of Migraine Pharmacotherapies" provides levels of evidence for medication efficacy for acute treatment of migraine. The goal of this companion paper is to provide guidance on how to choose between evidence-based treatment options, and, based on the clinical characteristics of the patient and their migraine attacks, to provide guidance on designing an individualized strategy for managing migraine attacks. The acute pharmacological treatments described in the American Headache Society evidence assessment can be divided into those initially taken by the patient during the headache phase of the migraine attack, those taken by the patient later in the attack when initial treatments fail, and those administered intravenously or intramuscularly in urgent care settings...
July 2016: Headache
https://www.readbyqxmd.com/read/27186935/clinical-aspects-of-benign-paroxysmal-positional-vertigo-associated-with-migraine
#4
Sertaç Yetiser, Meltem Hale Alpsan Gokmen
INTRODUCTION: Whether clinical features in patients with BPPV and migraine differ from patients with BPPV without migraine is unknown. OBJECTIVES: The aim of this study is to compare clinical aspects of patients with or without migraine. MATERIALS AND METHOD: 263 patients with BPPV were enrolled. Patients were investigated in terms of age, gender, symptoms, affected side, type of BPPV and the cure rate. Data were compared in patients with and without migraine...
2015: International Tinnitus Journal
https://www.readbyqxmd.com/read/27080086/update-on-new-daily-persistent-headache
#5
REVIEW
Hida Nierenburg, Lawrence C Newman
New daily persistent headache (NDPH) is an uncommon and under-recognized primary headache disorder. Clinically, NDPH may resemble migraine or tension-type headache. Unlike migraine or tension-type headaches, however, a distinguishing feature of NDPH is that the majority of patients with NDPH can pinpoint the exact date of onset of symptoms. While cases can arise de novo, in multiple reports, a viral illness precedes the onset of headache. NDPH has two temporal profiles: a self-limited form that resolves spontaneously without treatment and a refractory, persistent form in which headaches continue unabated for years...
June 2016: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/26961321/when-does-chronic-migraine-strike-a-clinical-comparison-of-migraine-according-to-the-headache-days-suffered-per-month
#6
M Torres-Ferrús, M Quintana, J Fernandez-Morales, J Alvarez-Sabin, P Pozo-Rosich
INTRODUCTION: According to the IHCD-3β classification, chronic migraine (CM) is headache occurring on 15 or more days/month. Episodic migraine (EM) can be divided into low frequency (LFEM) and high frequency (HFEM) depending on the headache days suffered per month. METHODS: We performed a clinical comparison of migraine characteristics according to monthly headache days suffered. Patients were divided into three groups: LFEM (1-9 headache days/month), HFEM (10-14 headache days/month) and CM (≥15 headache days/month)...
March 8, 2016: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/26952049/patent-foramen-ovale-and-migraine-closing-the-debate-a-review
#7
REVIEW
Nauman Tariq, Stewart J Tepper, Jennifer S Kriegler
BACKGROUND: A link between patent foramen ovale (PFO) and migraine as well as the utility of closure of PFO and its effect on migraine have been subjects of debate. The present review is an effort to gather the available evidence on this topic and formulate recommendations. METHODS: A systematic search of electronic databases (Medline, Embase, Cochrane Library) was performed. A separate search in associated reference lists of identified studies was done. Observational studies and clinical trials published in English using the International Headache Society criteria for diagnosis of migraine were included in the analysis...
March 2016: Headache
https://www.readbyqxmd.com/read/26877296/co-44-the-paradoxical-significance-of-headache-in-hypertension
#8
M Serraille, P Y Courand, N Girerd, G Demarquay, H Milon, B Harbaoui, P Lantelme
BACKGROUND: The cardiovascular prognostic value of various types of headache, particularly migraine, in the general population is still controversial. The aim of the present study was to assess this prognostic value for all-cause, cardiovascular and stroke mortalities, in hypertensive patients. METHODS: 1914 hypertensive individuals were categorized first, according to the absence or the presence of headache and then according to 3 subtypes of headache: migraine, "daily headache" and "other headache"...
December 2015: Annales de Cardiologie et D'angéiologie
https://www.readbyqxmd.com/read/26861893/long-term-pain-reduction-does-not-imply-improved-functional-outcome-in-patients-treated-with-combined-supraorbital-and-occipital-nerve-stimulation-for-chronic-migraine
#9
Shannon W Clark, Chengyuan Wu, David W Boorman, Nohra Chalouhi, Mario Zanaty, Michael Oshinsky, William B Young, Stephen D Silberstein, Ashwini D Sharan
BACKGROUND: Dual supraorbital and occipital nerve stimulation (SONS and ONS) have shown promising efficacy in treating primary headaches. However, its functional outcome is not well studied. OBJECTIVE: To present functional outcome studies of combined SONS and ONS for chronic migraine using verified metrics. METHOD: Consecutive patients with both SONS and ONS assessed with Migraine Disability Assessment (MIDAS) and Beck Depression Index (BDI) both preoperatively and postoperatively were studied...
July 2016: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/26558263/ocular-blood-flow-and-normal-tension-glaucoma
#10
REVIEW
Ning Fan, Pei Wang, Li Tang, Xuyang Liu
Normal tension glaucoma (NTG) is known as a multifactorial optic neuropathy characterized by progressive retinal ganglion cell death and glaucomatous visual field loss, even though the intraocular pressure (IOP) does not exceed the normal range. The pathophysiology of NTG remains largely undetermined. It is hypothesized that the abnormal ocular blood flow is involved in the pathogenesis of this disease. A number of evidences suggested that the vascular factors played a significant role in the development of NTG...
2015: BioMed Research International
https://www.readbyqxmd.com/read/26439579/pp-14-effects-of-body-mass-index-on-gastric-motility-in-children-with-abdominal-pain-predominant-functional-gastrointestinal-disorders
#11
Amaranath Karunanayake, Niranga Manjuri Devanarayana, Shaman Rajindrajith
INTRODUCTION: There is evidence that overweight children have a higher prevalence of functional gastrointestinal disorders (FGIDs) than normal-weight children. Objective of this study was to assess the effects of body mass index (BMI) on gastric motility abnormalities in children with abdominal pain-predominant FGIDs (AP-FGIDs). METHODS: Gastric motility parameters of 100 children with AP-FGIDs (61(61%) girls, mean age 8.0 years [SD 2.1years] and 50 healthy controls (30 (30%) boys, mean age 8...
October 2015: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/26345726/factors-influencing-migraine-recurrence-after-infusion-and-inpatient-migraine-treatment-in-children-and-adolescents
#12
Katherine M Cobb-Pitstick, Andrew D Hershey, Hope L O'Brien, Marielle A Kabbouche, Susan LeCates, Shannon White, Polly Vaughn, Paula Manning, Ann Segers, Judith Bush, Paul S Horn, Joanne Kacperski
OBJECTIVE: To evaluate factors that influence migraine recurrence after outpatient infusion or inpatient treatment for intractable migraine. BACKGROUND: Recurrence of migraine after acute treatment in an infusion center or an inpatient setting is not well documented in children and adolescents. Given the multifactorial pathogenesis of migraines, multiple factors may influence migraine recurrence. It has been reported that treatment with steroids may reduce the risk of migraine recurrence...
November 2015: Headache
https://www.readbyqxmd.com/read/26338328/chloride-cotransporters-as-a-molecular-mechanism-underlying-spreading-depolarization-induced-dendritic-beading
#13
Annette B Steffensen, Jeremy Sword, Deborah Croom, Sergei A Kirov, Nanna MacAulay
UNLABELLED: Spreading depolarizations (SDs) are waves of sustained neuronal and glial depolarization that propagate massive disruptions of ion gradients through the brain. SD is associated with migraine aura and recently recognized as a novel mechanism of injury in stroke and brain trauma patients. SD leads to neuronal swelling as assessed in real time with two-photon laser scanning microscopy (2PLSM). Pyramidal neurons do not express aquaporins and thus display low inherent water permeability, yet SD rapidly induces focal swelling (beading) along the dendritic shaft by unidentified molecular mechanisms...
September 2, 2015: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/26337644/-positioning-of-headache-units-in-the-field-of-neurology-the-importance-of-onabotulinumtoxina-and-other-therapies-in-the-treatment-of-headaches
#14
REVIEW
M Torres-Ferrus, P Pozo-Rosich
Chronic migraine is a disease that affects 0.5-2.5% of the population, depending on the statistics that are analysed and the definition of chronic migraine that is used. It is extraordinarily disabling, since it does not allow the sufferer to carry out any of their scheduled personal, professional or social activities, and it has a great impact on the patients' quality of life, as measured on disability, quality of life and impact on daily activities scales. Yet, nowadays there are treatments that have proven to be effective in cases of chronic migraine, such as OnabotulinumtoxinA...
2015: Revista de Neurologia
https://www.readbyqxmd.com/read/26320523/diphenhydramine-as-adjuvant-therapy-for-acute-migraine-an-emergency-department-based-randomized-clinical-trial
#15
RANDOMIZED CONTROLLED TRIAL
Benjamin W Friedman, Lisa Cabral, Victoria Adewunmi, Clemencia Solorzano, David Esses, Polly E Bijur, E John Gallagher
STUDY OBJECTIVE: More than 1 million patients present to US emergency departments (EDs) annually seeking care for acute migraine. Parenteral antihistamines have long been used in combination with antidopaminergics such as metoclopramide to treat acute migraine in the ED. High-quality data supporting this practice do not exist. We determine whether administration of diphenhydramine 50 mg intravenously+metoclopramide 10 mg intravenously results in greater rates of sustained headache relief than placebo+metoclopramide 10 mg intravenously...
January 2016: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/26266080/migraine-treatment-a-chain-of-adverse-effects
#16
Tiago Sousa Veloso, Mariana Seixas Cambão
This clinical vignette presents a 14 years old female, with a past medical history relevant only for migraine with typical aura of less than monthly frequency, complaining of a severe unilateral headache with rising intensity for the previous 4 h, associated with nausea, vomiting, photophobia and phonophobia. This episode of migraine with aura in a patient with recurrent migraine was complicated by side effects of medical diagnostic and therapeutic procedures (extrapyramidal symptoms, delirium, post-lumbar puncture headache, hospital admission) all of which could have been prevented-quaternary prevention...
2015: SpringerPlus
https://www.readbyqxmd.com/read/26165526/persistent-patent-foramen-ovale-pfo-implications-for-safe-diving
#17
EDITORIAL
Peter Germonpré
Diving medicine is a peculiar specialty. There are physicians and scientists from a wide variety of disciplines with an interest in diving and who all practice 'diving medicine': the study of the complex whole-body physiological changes and interactions upon immersion and emersion. To understand these, the science of physics and molecular gas and fluid movements comes into play. The ultimate goal of practicing diving medicine is to preserve the diver's health, both during and after the dive. Good medicine starts with prevention...
June 2015: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/26082134/putative-pathophysiological-mechanisms-in-recurrent-hemicrania-from-aortic-dissection-a-case-report
#18
Joseph Kamtchum Tatuene, Sophie Excoffier, Jean-Paul Vallee, Andreas Kleinschmidt
BACKGROUND: Transient or permanent neurological symptoms occur in 17-40% of patients with aortic dissection. They can distract from or even mask the underlying life-threatening condition. CASE PRESENTATION: We present the case of a young Caucasian man who consulted for recurrent episodes of stereotyped right-sided sudden-onset severe headache. Upon questioning, he also reported a dull chest pain. Clinical examination and brain magnetic resonance imaging were unremarkable...
2015: BMC Research Notes
https://www.readbyqxmd.com/read/26017514/migraine-with-aura-and-patent-foramen-ovale-myth-or-reality
#19
REVIEW
C Finocchi, M Del Sette
Several observational studies report that subjects with migraine with aura have a higher prevalence of right-to left shunt, commonly due to patent foramen ovale, and that patent foramen ovale is more prevalent in subjects with migraine with aura. Although migraine without aura has been less extensively studied, it does not seem to be associated with an increased prevalence of right-to left shunt. The mechanism that underlies the possible relationship between patent foramen ovale and migraine with aura remains speculative...
May 2015: Neurological Sciences
https://www.readbyqxmd.com/read/25792408/persistent-trigeminal-artery-as-a-rare-cause-of-ischaemic-lesion-and-migraine-like-headache
#20
S Uhlig, J Kurzepa, E Czekajska-Chehab, G Staśkiewicz, M K Polar, M Nastaj, E Stochmal, A Drop
The persistent trigeminal artery (PTA) is a rare remnant of the embryonic intracranial circulatory system that forms a carotid-vertebrobasilar anastomosis. In most cases PTA does not have clear clinical implications. However, some authors report the association of PTA occurrence with vertigo, dizziness and nerve palsy, resulting in diplopia, strabismus or trigeminal neuralgia in patients. In rare cases it may also be related to posterior cerebral circulation strokes. This work reports the case of a female patient who presented with migraine-like headache and an ischaemic lesion in the left temporal lobe in association with PTA...
2015: Folia Morphologica (Warsz)
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