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Orthopaedic implant

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https://www.readbyqxmd.com/read/28820728/radiostereometric-migration-measurement-of-an-uncemented-cerafit%C3%A2-femoral-stem-26-patients-followed-for-10-years
#1
Stefan Sesselmann, Yotung Hong, Frank Schlemmer, Isabell Hussnaetter, Lutz A Mueller, Raimund Forst, Franz Tschunko
Radiostereometric analysis (RSA) is the gold standard for evaluating micromotions of orthopaedic implants. The method is applied for identifying novel design weaknesses in endoprostheses. Current research frequently assesses relatively short time periods. Short-term RSA studies have been widely used for predicting the long-term stability of many hip prosthetic designs, but only a few studies have focused on uncemented hip implants, especially for extended periods. The purpose of this study was to analyse the migration pattern of the Cerafit® femoral stem within 10 years and to verify the predictive value of short-term RSA after 2 years for this uncemented femoral hip stem...
August 18, 2017: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/28819908/the-effect-of-cationically-modified-phosphorylcholine-polymers-on-human-osteoblasts-in-vitro-and-their-effect-on-bone-formation-in-vivo
#2
Jonathan M Lawton, Mariam Habib, Bingkui Ma, Roger A Brooks, Serena M Best, Andrew L Lewis, Neil Rushton, William Bonfield
The effect of introducing cationic charge into phosphorylcholine (PC)-based polymers has been investigated in this study with a view to using these materials as coatings to improve bone formation and osseointegration at the bone-implant interface. PC-based polymers, which have been used in a variety of medical devices to improve biocompatibility, are associated with low protein adsorption resulting in reduced complement activation, inflammatory response and cell adhesion. However, in some applications, such as orthopaedics, good integration between the implant and bone is needed to allow the distribution of loading stresses and a bioactive response is required...
August 17, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28817244/key-developments-that-impacted-the-field-of-mechanobiology-and-mechanotransduction
#3
Michelle Wall, David Butler, Alicia El Haj, Josephine C Bodle, Elizabeth G Loboa, Albert J Banes
Advances in mechanobiology have evolved through insights from multiple disciplines including structural engineering, biomechanics, vascular biology, and orthopaedics. In this paper, we reviewed the impact of key reports related to the study of applied loads on tissues and cells and the resulting signal transduction pathways. We addressed how technology has helped advance the burgeoning field of mechanobiology (over 33,600 publications from 1970-2016). We analyzed the impact of critical ideas and then determined how these concepts influenced the mechanobiology field by looking at the citation frequency of these reports as well as tracking how the overall number of citations within the field changed over time...
August 17, 2017: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/28802424/can-antibiotic-impregnated-cement-nail-achieve-both-infection-control-and-bony-union-in-infected-diaphyseal-femoral-non-unions
#4
Chetan Pradhan, Atul Patil, Chetan Puram, Dheeraj Attarde, Parag Sancheti, Ashok Shyam
BACKGROUND: Infected non-union is complex and debilitating disorder affecting orthopaedic surgeon and patient in terms of cost and time. Many methods are described in the literature for treatment of infected non-union. Local high concentration of antibiotic and mechanical stability of antibiotic cement impregnated intramedullary nail (ACIIN) proves cost and time effective. Recently it was suggested that ACIIN can achieve both union and infection control in infected non-unions with bone gap less than 4cm...
August 2017: Injury
https://www.readbyqxmd.com/read/28802415/augmentation-of-intramedullary-nailing-in-unstable-intertrochanteric-fractures-using-cerclage-wire-and-lag-screws-a-comparative-study
#5
Sunil Govind Kulkarni, Sushrut Sudhir Babhulkar, Sujay Milind Kulkarni, Govind Shivram Kulkarni, Madhura Sujay Kulkarni, Raviraj Patil
BACKGROUND: Unstable intertrochanteric fractures present a challenge to orthopaedic surgeons, with varied geometry of the fractures and a wide choice of implants and techniques. The patients are usually osteoporotic, with multiple co-morbidities and poor tolerance for complications and re-operations. Lateral wall reconstruction and stability of the trochanteric fragments are considered important in providing a better outcome of these difficult injuries. We present a technique of lateral wall and trochanteric reconstruction using Cerclage wires and lag screws in the greater trochanter in addition to intramedullary nailing, and the radiological and functional outcome of this technique of augmentation...
August 2017: Injury
https://www.readbyqxmd.com/read/28801390/the-benefits-of-hardware-removal-in-patients-with-pain-or-discomfort-after-fracture-healing-of-the-ankle-a-systematic-review-protocol
#6
Alexandra Thune, Mårten Hagelberg, Hans Nåsell, Olof Sköldenberg
INTRODUCTION: For any orthopaedic surgeon working with trauma; ankle fractures are one of the most common injuries treated. The treatment of ankle fractures can be conservative, using external fixation, but more commonly the fractures are treated with open reduction and internal fixation. Residual pain and discomfort are common in patients after surgical treatment of fractures of the ankle. Sometimes it is difficult to determine whether the pain or discomfort is due to the implants left in situ or the primary injury itself...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28793979/outcome-of-prosthesis-matched-and-unmatched-patella-components-in-primary-and-revision-total-knee-replacement
#7
Peter L Lewis, Ai E Gamboa, David G Campbell, Michelle Lorimer
BACKGROUND: Although knee replacements have specifically designed patella prostheses that correspond to the geometry of their femoral components, a patella prosthesis that is unmatched to the femoral component may occasionally be inserted. In revision total knee arthroplasty (TKA), an originally resurfaced patella may be left, but the femoral component revised to one that does not match the patella. Few studies have compared the outcome of matched and unmatched patella components in TKA...
August 6, 2017: Knee
https://www.readbyqxmd.com/read/28793839/roughness-and-hydrophilicity-as-osteogenic-biomimetic-surface-properties
#8
Barbara Boyan, Ethan Major Lotz, Zvi Schwartz
Successful dental and orthopaedic implant outcomes are determined by the degree of osseointegration. Over the last 60 years, endosseous implants have evolved to stimulate osteogenesis without the need for exogenous biologics like bone morphogenetic proteins. An understanding of the interaction between cells and how cells interact with the physical features characteristics of their environments have has led to the development ofse bioactive implants. Implant surfaces that mimic the inherent chemistry, topography, and hydrophilicity wettability of native bone have been shown to provide cells in the osteoblast lineage cells with the structural cues to promote tissue regeneration and net new bone formation...
August 10, 2017: Tissue Engineering. Part A
https://www.readbyqxmd.com/read/28791150/chromium-oxide-coatings-with-the-potential-for-eliminating-the-risk-of-chromium-ion-release-in-orthopaedic-implants
#9
A M Oje, A A Ogwu
Chromium oxide coatings prepared by radiofrequency reactive magnetron sputtering on stainless steel substrates were exposed to Ringer's physiological solution and tested for their electrochemical corrosion stability using an open circuit potential measurement, potentiodynamic polarization, electrochemical impedance spectroscopy and Mott-Schottky analysis. The coatings were found to be predominantly Cr2O3, based on the observation of the dominance of [Formula: see text] and Eg symmetric modes in our Raman spectroscopic investigation and the Eu vibrational modes in our Fourier transform infrared spectroscopic measurements on the coatings...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28774246/iatrogenic-injuries-of-the-palmar-branch-of-the-median-nerve-following-volar-plate-fixation-of-the-distal-radius
#10
Deepak Samson, Dominic M Power
BACKGROUND: Our aims were to identify iatrogenous injuries to the palmar branch of the median nerve sustained during volar plate fixation of the distal radius, make the clinician aware of this relatively uncommon complication of distal radius fixation, to emphasise common threads in symptomatology and to propose an algorithm for evaluation and management. METHODS: Retrospectively interrogating our database over a 5 year period, the case records, neurophysiology records, operative records, therapy records were reviewed...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28774236/locking-screw-migration-to-the-palm-four-years-following-surgical-implantation-of-distal-radius-locking-plate
#11
Yousef Marwan, Asim M Makhdom, Gregory Berry
Hardware-related complications are rare in patients with distal radius fractures who were surgically fixed with volar-locking plates. In this report, we present a case of locking screw loosening and migration to the palm four years following the treatment of type 23-C1 distal radius fracture with a volar locking-plate. This complication occurred without evidence of trauma, infection, non-union or plate breakage. Orthopaedic surgeons should be aware of such rare complication and add it to the list of potential postoperative complications when counseling their patients preoperatively...
September 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/28773240/metallic-biomaterials-current-challenges-and-opportunities
#12
REVIEW
Karthika Prasad, Olha Bazaka, Ming Chua, Madison Rochford, Liam Fedrick, Jordan Spoor, Richard Symes, Marcus Tieppo, Cameron Collins, Alex Cao, David Markwell, Kostya Ken Ostrikov, Kateryna Bazaka
Metallic biomaterials are engineered systems designed to provide internal support to biological tissues and they are being used largely in joint replacements, dental implants, orthopaedic fixations and stents. Higher biomaterial usage is associated with an increased incidence of implant-related complications due to poor implant integration, inflammation, mechanical instability, necrosis and infections, and associated prolonged patient care, pain and loss of function. In this review, we will briefly explore major representatives of metallic biomaterials along with the key existing and emerging strategies for surface and bulk modification used to improve biointegration, mechanical strength and flexibility of biometals, and discuss their compatibility with the concept of 3D printing...
July 31, 2017: Materials
https://www.readbyqxmd.com/read/28771196/preparation-and-evaluation-of-dexamethasone-dex-growth-and-differentiation-factor-5-gdf-5-surface-modified-titanium-using-%C3%AE-cyclodextrin-conjugated-heparin-cd-hep-for-enhanced-osteogenic-activity-in-vitro-and-in-vivo
#13
Dae Hyeok Yang, Sun-Jung Yoon, Deok-Won Lee
The most ideal implant models in the dental and orthopedic fields to minimize the failure rate of implantation involve the improvement of osseointegration with host bone. Therefore, a focus of this study is the preparation of surface-modified titanium (Ti) samples of disc and screw types using dexamethasone (DEX) and/or growth and differentiation factor-5 (GDF-5), as well as the evaluation of their efficacies on bone formation in vitro and in vivo. X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and contact angle measurement were used to evaluate the surface chemical composition, surface morphology and wettability, respectively...
August 3, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28768712/factors-influencing-the-reporting-of-adverse-medical-device-events-qualitative-interviews-with-physicians-about-higher-risk-implantable-devices
#14
Anna R Gagliardi, Ariel Ducey, Pascale Lehoux, Thomas Turgeon, Sue Ross, Patricia Trvovich, Anthony Easty, Chaim Bell, David Urbach
BACKGROUND: Postmarket surveillance of medical devices is reliant on physician reporting of adverse medical device events (AMDEs). Little is known about factors that influence whether and how physicians report AMDEs, an essential step in developing behaviour change interventions. This study explored factors that influence AMDE reporting. METHODS: Qualitative interviews were conducted with physicians who differed by specialties that implant cardiovascular and orthopaedic devices prone to AMDEs, geography and years in practice...
August 2, 2017: BMJ Quality & Safety
https://www.readbyqxmd.com/read/28760844/inhibitory-effect-ofquercetinon-titaniumparticle-inducedendoplasmic-reticulum-stress-ers-related-apoptosisandin-vivoosteolysis
#15
Laibo Zhang, Zhoubin Tian, Wei Li, Xianquan Wang, Zhentao Man, Shui Sun
Wear particle-induced periprosthetic osteolysis is the main cause of aseptic loosening of orthopaedic implants. The aim of this study is to determine the protective effect of quercetin (QUE) against titanium (Ti) particle-induced ERS-related apoptosis and osteolysis. In this study, RAW264.7 cells were pretreated with different concentrations (40, 80, and 160 μmol/l) of QUE for 30 min and then treated with Ti particle (5 mg/ml) for 24 h. Cell viability and apoptosis were determined using MTT assay and Annexin V-FITC apoptosis detection kit, respectively...
July 31, 2017: Bioscience Reports
https://www.readbyqxmd.com/read/28759643/in-vitro-comparison-between-%C3%AE-tocopheryl-acetate-and-%C3%AE-tocopheryl-phosphate-against-bacteria-responsible-of-prosthetic-and-joint-infections
#16
Alessandro Bidossi, Monica Bortolin, Marco Toscano, Elena De Vecchi, Carlo L Romanò, Roberto Mattina, Lorenzo Drago
Biofilm-related infections represent a recurrent problem in the orthopaedic setting. In recent years, great interest was directed towards the identification of novel molecules capable to interfere with pathogens adhesion and biofilm formation on implant surfaces. In this study, two stable forms of α-tocopherol, the hydrophobic acetate ester and the water-soluble phosphate ester, were tested in vitro as coating for titanium prosthesis. Antimicrobial activity against microorganisms responsible of prosthetic and joints infections was assessed by broth microdilution method...
2017: PloS One
https://www.readbyqxmd.com/read/28750551/midterm-results-of-the-salto-talaris-total-ankle-arthroplasty
#17
Matthew G Stewart, Cindy L Green, Samuel B Adams, James K DeOrio, Mark E Easley, James A Nunley
BACKGROUND: The Salto Talaris total ankle replacement is a modern fixed-bearing implant used to treat symptomatic ankle arthritis with the goals of providing pain relief, restoring mechanical alignment, and allowing motion of the ankle joint. The goal of this study was to report the midterm clinical results of one of the largest cohort of patients in the United States who underwent ankle replacement with this prosthesis. METHODS: This is a review of patients with a minimum of 5 years up to 10 years' follow-up...
July 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/28746053/bacterial-attachment-on-titanium-surfaces-is-dependent-on-topography-and-chemical-changes-induced-by-nonthermal-atmospheric-pressure-plasma
#18
Won-Seok Jeong, Jae-Sung Kwon, Jung-Hwan Lee, Soo-Hyuk Uhm, Eun Ha Choi, Kwang-Mahn Kim
Here, we investigated the antibacterial effects of chemical changes induced by nonthermal atmospheric pressure plasma (NTAPP) on smooth and rough Ti. The morphologies of smooth and rough surfaces of Ti were examined using scanning electron microscopy (SEM). Both Ti specimens were then treated for 10 min by NTAPP with nitrogen gas. The surface roughness, chemistry, and wettability were examined by optical profilometry, x-ray photoelectron spectroscopy, and water contact angle analysis, respectively. Bacterial attachment was measured by determining the number of colony forming units and by SEM analysis...
July 26, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28734187/proximal-femoral-nail-antirotation-versus-hemiarthroplasty-in-the-treatment-of-senile-intertrochanteric-fractures-case-report
#19
Xiangping Luo, Shengmao He, Dingshi Zeng, Lijun Lin, Qi Li
BACKGROUND: Primary hemiarthroplasty was recommended by some surgeons as the preferred choice in treating unstable senile intertrochanteric fractures with osteoporosis. However, many studies reported that proximal femoral nail antirotation (PFNA) currently was as an optimal implant for the treatment of different type of intertrochanteric fractures. Which method is better for treating senile intertrochanteric fractures remains controversial due to the insufficient clinical evidences. METHODS: We reviewed all consecutive senile intertrochanteric fractures treated with PFNA or cemented hemiarthroplasty at our institution between July 2010 and March 2015...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28733042/complications-and-unplanned-outcomes-following-operative-treatment-of-tibial-plateau-fractures
#20
David Kugelman, Abdullah Qatu, Jack Haglin, Phillip Leucht, Sanjit Konda, Kenneth Egol
INTRODUCTION: The operative management of tibial plateau fractures is challenging and post-operative complications do occur. The purpose of this study was three-fold. 1). To report complications and unplanned outcomes in patients who had sustained tibial plateau fractures and were operatively managed 2). To report predictors of these post-operative events 3). To report if differences in clinical outcomes exist in patients who sustained a post-operative event. METHODS: Over 11 years, all tibial plateau fractures were prospectively followed...
July 12, 2017: Injury
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