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https://www.readbyqxmd.com/read/28917399/variability-in-angle-%C3%AE%C2%BA-and-its-influence-on%C3%A2-higher-order-aberrations-in%C3%A2-pseudophakic-eyes
#1
Annette Harrer, Nino Hirnschall, Juan Tabernero, Pablo Artal, Petra Draschl, Sophie Maedel, Oliver Findl
PURPOSE: To observe the variability in angle κ in pseudophakic patients and assess its correlation with optical biometry measurements and higher-order aberrations (HOAs). SETTING: Hanusch Hospital, Vienna, Austria. DESIGN: Prospective case series. METHODS: This study included patients who had cataract surgery 3 months to 1 year before study recruitment. In all cases, Purkinje meter images were taken. In addition, partial coherence interferometry measurement (IOLMaster) of the axial intraocular lens (IOL) position was performed...
August 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/28916859/near-infrared-cholecystocholangiography-with-direct-intragallbladder-indocyanine-green-injection-preliminary-clinical-results
#2
Yu-Yin Liu, Chien-Hung Liao, Michele Diana, Shang-Yu Wang, Seong-Ho Kong, Chun-Nan Yeh, Bernard Dallemagne, Jacques Marescaux, Ta-Sen Yeh
BACKGROUND: Near-infrared (NIR) fluorescence cholangiography by systemic administration of indocyanine green (ICG) enhances the visualization of the biliary tree anatomy. However, the simultaneous enhancement of liver parenchyma can disturb the visualization of critical details. We herein proposed a new technique of NIR cholecystocholangiography by intragallbladder ICG injection to increase the safety during laparoscopic cholecystectomy. METHODS: A total of 46 patients scheduled for laparoscopic cholecystectomy for symptomatic lithiasis (n = 21) or cholecystitis (n = 25) were enrolled...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28915248/invasion-strategy-and-abiotic-activity-triggers-for-non-native-gobiids-of-the-river-rhine
#3
Jan Baer, Frank Hartmann, Alexander Brinker
The 24 hour activity patterns of three non-native gobiids (round goby Neogobius melanostomus, Western tubenose goby Proterorhinus semilunaris and bighead goby Ponticola kessleri) were assessed over 46 consecutive months between 2011 and 2014 from their occurrence in the cooling water intake of a nuclear power plant on the River Rhine, Germany. In total, 117717 gobiids were identified and classified. The occurrence of all three species varied strongly between sampling years, and species-specific activity triggers were identified...
2017: PloS One
https://www.readbyqxmd.com/read/28915214/non-hemodynamic-effects-of-catecholamines
#4
Clair Hartmann, Peter Radermacher, Martin Wepler, Benedikt Nußbaum
Circulatory shock is defined as an imbalance between tissue oxygen supply and demand, and mostly results from a loss of blood volume, cardiac pump failure, and/or reduction of vasomotor tone. The clinical hallmarks of circulatory shock are arterial hypotension and lactate acidosis. Since the degree and duration of hypotension are major determinants of outcome, vasopressor administration represents a cornerstone therapy to treat these patients. Current guidelines recommend the use of catecholamines as the drug of first choice...
October 2017: Shock
https://www.readbyqxmd.com/read/28912569/two-dimensional-dirac-particles-in-a-p%C3%A3-schl-teller-waveguide
#5
R R Hartmann, M E Portnoi
We obtain exact solutions to the two-dimensional (2D) Dirac equation for the one-dimensional Pöschl-Teller potential which contains an asymmetry term. The eigenfunctions are expressed in terms of Heun confluent functions, while the eigenvalues are determined via the solutions of a simple transcendental equation. For the symmetric case, the eigenfunctions of the supercritical states are expressed as spheroidal wave functions, and approximate analytical expressions are obtained for the corresponding eigenvalues...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28905982/vector-borne-diseases-in-cats-in-germany
#6
Michèle Bergmann, Katrin Hartmann
Vector-borne diseases (VBDs) are caused by a wide range of pathogens, which are transmitted by a variety of vectors, such as ticks and fleas. As a result of climate changes, more vector-borne diseases are becoming endemic in Germany, not only in dogs, but also in cats. For some of the pathogens prevalence data still need to be investigated in Germany. However, natural infections with Bartonella, Anaplasma, haemotropic Mycoplasma and Borrelia species have already been described in German cats. Clinical relevance of these pathogens is not fully understood, and it is still unknown, why most infected cats stay asymptomatic and which predisposing factors contribute to the development of clinical signs in cats...
September 13, 2017: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/28903120/opening-the-black-box-of-cognitive-behavioural-case-management-in-clients-with-ultra-high-risk-for-psychosis
#7
Jessica A Hartmann, Patrick D McGorry, Stefanie J Schmidt, G Paul Amminger, Hok Pan Yuen, Connie Markulev, Gregor E Berger, Eric Y H Chen, Lieuwe de Haan, Ian B Hickie, Suzie Lavoie, Meredith J McHugh, Nilufar Mossaheb, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Rössler, Miriam R Schäfer, Monika Schlögelhofer, Stefan Smesny, Andrew Thompson, Swapna Kamal Verma, Alison R Yung, Barnaby Nelson
BACKGROUND: Cognitive-behavioural therapy (CBT) is the first-choice treatment in clients with ultra-high risk (UHR) for psychosis. However, CBT is an umbrella term for a plethora of different strategies, and little is known about the association between the intensity and content of CBT and the severity of symptomatic outcome. METHODS: A sample of 268 UHR participants received 6 months of CBT with case management (CBCM) in the context of the multi-centre NEURAPRO trial with monthly assessments of attenuated psychotic symptoms (APS)...
September 14, 2017: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/28892730/approaches-to-modelling-radioactive-contaminations-in-forests-overview-and-guidance
#8
REVIEW
A Diener, P Hartmann, L Urso, J Vives I Batlle, M A Gonze, P Calmon, M Steiner
Modelling the radionuclide cycle in forests is important in case of contamination due to acute or chronic releases to the atmosphere and from underground waste repositories. This article describes the most important aspects to consider in forest model development. It intends to give an overview of the modelling approaches available and to provide guidance on how to address the quantification of radionuclide transport in forests. Furthermore, the most important gaps in modelling the radionuclide cycle in forests are discussed and suggestions are presented to address the variability of forest sites...
September 8, 2017: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/28890368/cyp17a1-independent-production-of-the-neurosteroid-derived-5%C3%AE-pregnan-3%C3%AE-6%C3%AE-diol-20-one-in-androgen-responsive-prostate-cancer-cell-lines-under-serum-starvation-and-inhibition-by-abiraterone
#9
Antonio G Gomes de Mello Martins, Giuseppe Allegretta, Gerhard Unteregger, Jörg Haupenthal, Jens Eberhard, Michael Hoffmann, Jill A van der Zee, Kerstin Junker, Michael Stöckle, Rolf Müller, Rolf W Hartmann, Carsten-H Ohlmann
CYP17A1-independent intratumoral steroid hormone synthesis is regarded as one possible explanation for resistance to treatment with the CYP17-inhibitor Abiraterone (Abi). The aim of our study was therefore to investigate the steroid metabolism of prostate cancer cells under serum starvation and the effects of Abi treatment. We assessed steroid metabolism in a panel of prostate cancer cells under serum starvation by radioactivity detector-coupled HPLC and HPLC-ESI-ToF-mass spectrometry after treatment with pregnenolone, progesterone and allopregnanolone...
September 7, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28887494/sulfonolipids-as-novel-metabolite-markers-of-alistipes-and-odoribacter-affected-by-high-fat-diets
#10
Alesia Walker, Barbara Pfitzner, Mourad Harir, Monika Schaubeck, Jelena Calasan, Silke S Heinzmann, Dmitrij Turaev, Thomas Rattei, David Endesfelder, Wolfgang Zu Castell, Dirk Haller, Michael Schmid, Anton Hartmann, Philippe Schmitt-Kopplin
The gut microbiota generates a huge pool of unknown metabolites, and their identification and characterization is a key challenge in metabolomics. However, there are still gaps on the studies of gut microbiota and their chemical structures. In this investigation, an unusual class of bacterial sulfonolipids (SLs) is detected in mouse cecum, which was originally found in environmental microbes. We have performed a detailed molecular level characterization of this class of lipids by combining high-resolution mass spectrometry and liquid chromatography analysis...
September 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28886701/the-loss-of-function-disease-mutation-g301r-in-the-na-k-atpase-%C3%AE-2-isoform-decreases-lesion-volume-and-improves-functional-outcome-after-acute-spinal-cord-injury-in-mice
#11
Ditte Gry Ellman, Toke Jost Isaksen, Minna Christiansen Lund, Safinaz Dursun, Martin Wirenfeldt, Louise Helskov Jørgensen, Karin Lykke-Hartmann, Kate Lykke Lambertsen
BACKGROUND: The Na(+)/K(+)-ATPases are transmembrane ion pumps important for maintenance of ion gradients across the plasma membrane that serve to support multiple cellular functions, such as membrane potentials, regulation of cellular volume and pH, and co-transport of signaling transmitters in all animal cells. The α2Na(+)/K(+)-ATPase subunit isoform is predominantly expressed in astrocytes, which us the sharp Na(+)-gradient maintained by the sodium pump necessary for astroglial metabolism...
September 8, 2017: BMC Neuroscience
https://www.readbyqxmd.com/read/28886402/identification-and-initial-management-of-intoxication-by-alcohol-and-other-drugs-in-the-pediatric-emergency-room
#12
REVIEW
Thiago Gatti Pianca, Anne Orgle Sordi, Thiago Casarin Hartmann, Lisiavon Diemen
OBJECTIVE: To review the screening, diagnosis, evaluation, and treatment of intoxication by alcohol and other drugs in children and adolescents in the emergency scenario. DATA SOURCE: This was a narrative literature review. DATA SUMMARY: The detection of this problem in the emergency room can be a challenge, especially when its assessment is not standardized. The intentional and episodic use of large amounts of psychoactive substances by adolescents is a usual occurrence, and unintentional intoxication is more common in children younger than 12 years...
September 5, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28885663/removal-of-bile-acids-by-extracorporeal-therapies-an-in-vitro-study
#13
Jens Hartmann, Stephan Harm
INTRODUCTION: Bile acids (BAs) accumulating in the circulation in patients with liver failure are considered to be responsible for pruritus, which strongly impairs quality of life of the affected patients. The aim of this study was the in vitro characterization of different BAs regarding their removability with high-flux dialysis as well as with different adsorbents, and the evaluation of their binding to plasma proteins. METHODS: Dialysis experiments were conducted in pediatric circuits with human plasma...
September 5, 2017: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/28883011/rare-case-of-massive-bilateral-chylothorax
#14
Guramrinder Singh Thind, Dominika M Zoltowska, Yashwant Agrawal
We present a case of a 48-year-old woman who was referred from an outside hospital. There, she had initially underwent hysterectomy and left salpingo-oophorectomy for tubo-ovarian abscess. She later developed a colovaginal fistula and perforation of sigmoid colon and underwent Hartmann's procedure along with drainage of a left subphrenic abscess. Subsequently, she had to be intubated for acute respiratory failure and was transferred to our hospital. At our hospital, she was found to have massive bilateral pleural effusions...
September 7, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28883000/enhanced-acid-sphingomyelinase-activity-drives-immune-evasion-and-tumor-growth-in-non-small-cell-lung-carcinoma
#15
Katerina Kachler, Maximilian Bailer, Lisanne Heim, Fabian Schumacher, Martin Reichel, Corinna Holzinger, Sonja Trump, Susanne Mittler, Juliana Monti, Denis I Trufa, Ralf Joachim Rieker, Arndt Hartmann, Horia Sirbu, Burkhard Kleuser, Johannes Kornhuber, Susetta Finotto
The lipid hydrolase enzyme acid sphingomyelinase (ASM) is required for the conversion of the lipid cell membrane component sphingomyelin into ceramide. In cancer cells, ASM-mediated ceramide production is important for apoptosis, cell proliferation and immune modulation, highlighting ASM as a potential multimodal therapeutic target. In this study, we demonstrate elevated ASM activity in the lung tumor environment and blood serum of patients with non-small cell lung cancer (NSCLC). RNAi-mediated attenuation of SMPD1 in human NSCLC cells rendered them resistant to serum starvation-induced apoptosis...
September 7, 2017: Cancer Research
https://www.readbyqxmd.com/read/28881574/prevention-of-colitis-associated-cancer-by-selective-targeting-of-immunoproteasome-subunit-lmp7
#16
Niyati Vachharajani, Thorsten Joeris, Maik Luu, Sabrina Hartmann, Sabine Pautz, Elena Jenike, Georgios Pantazis, Immo Prinz, Markus J Hofer, Ulrich Steinhoff, Alexander Visekruna
Chronic inflammation is a well-known risk factor in development of intestinal tumorigenesis, although the exact mechanisms underlying development of colitis-associated cancer (CAC) still remain obscure. The activity and function of immunoproteasome has been extensively analyzed in the context of inflammation and infectious diseases. Here, we show that the proteasomal immunosubunit LMP7 plays an essential role in development of CAC. Mice devoid of LMP7 were resistant to chronic inflammation and formation of neoplasia, and developed virtually no tumors after AOM/DSS treatment...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28879662/setting-research-priorities-in-tobacco-control-a-stakeholder-engagement-project
#17
REVIEW
Nicola Lindson, Dan Richards-Doran, Laura Heath, Jamie Hartmann-Boyce
BACKGROUND AND AIMS: The Cochrane Tobacco Addiction Group (TAG) conducts systematic reviews of the evidence for tobacco cessation and prevention interventions. In 2016 TAG conducted a priority-setting, stakeholder engagement project to identify where further research is needed in the areas of tobacco control and smoking cessation. DESIGN: The project comprised two surveys and a workshop. A range of stakeholders participated, including members of the public (smokers and ex-smokers), clinicians, researchers, research funders, health-care commissioners and public health organizations...
September 6, 2017: Addiction
https://www.readbyqxmd.com/read/28879552/considerations-for-hartmann-s-reversal-and-hartmann-s-reversal-outcomes-a-multicenter-study
#18
Nir Horesh, Yonatan Lessing, Yaron Rudnicki, Ilan Kent, Haguy Kammar, Almog Ben-Yaacov, Yael Dreznik, Hagit Tulchinsky, Shmuel Avital, Eli Mavor, Nir Wasserberg, Hanoch Kashtan, Joseph M Klausner, Mordechai Gutman, Oded Zmora
PURPOSE: Hartmann's procedure is commonly practiced in emergent cases with the restoration of bowel continuity planned at a second stage. This study assessed the rate of restorations following Hartmann's procedure and evaluated factors affecting decision-making. METHODS: Data on patient demographics, comorbidities, causes for Hartmann's procedure, reversal rate, and complications were collected in a multicenter retrospective cohort study of patients who underwent Hartmann's procedure in five medical centers...
September 6, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28879465/-nodular-lymphocyte-dominant-hodgkin-s-lymphoma-lp-cells-show-recurrent-mutations-in-dusp2-sgk1-and-junb
#19
S Hartmann
No abstract text is available yet for this article.
September 6, 2017: Der Pathologe
https://www.readbyqxmd.com/read/28879204/dynamic-susceptibility-contrast-perfusion-magnetic-resonance-imaging-demonstrates-reduced-periventricular-cerebral-blood-flow-in-dogs-with-ventriculomegaly
#20
Martin J Schmidt, Malgorzata Kolecka, Robert Kirberger, Antje Hartmann
The nature of ventriculomegaly in dogs is still a matter of debate. Signs of increased intraventricular pressure and atrophy of the cerebral white matter have been found in dogs with ventriculomegaly, which would imply increased intraventricular pressure and, therefore, a pathological condition, i.e., to some extent. Reduced periventricular blood flow was found in people with high elevated intraventricular pressure. The aim of this study was to compare periventricular brain perfusion in dogs with and without ventriculomegaly using perfusion weighted-magnetic-resonance-imaging to clarify as to whether ventriculomegaly might be associated with an increase in intraventricular pressure...
2017: Frontiers in Veterinary Science
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