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Diabetes type 2 glucometer

Ejiofor T Ugwu, Casmir Jg Orjioke, Ekenechukwu E Young
BACKGROUND: Self monitoring of blood glucose (SMBG) is a useful adjunct to lifestyle modification and medications for optimal management of type 2 diabetes mellitus (DM). This study was aimed at evaluating the practice, cost and associations of SMBG in subjects with type 2 DM in Enugu, Nigeria. METHODS: In a cross-sectional survey conducted at the diabetes clinic in three hospitals, 366 type 2 diabetic subjects aged 18-65 years were consecutively interviewed. Socio-demographic and clinical information were documented and glycated hemoglobin was performed for all the participants...
October 14, 2016: Current Diabetes Reviews
Anjana Hulse, Suahma Rai, K M Prasanna Kumar
BACKGROUND: In children with type 1 diabetes, intensive diabetes management has been demonstrated to reduce long-term microvascular complications. At present, self-monitoring of blood glucose (SMBG) by patients at home and glycated hemoglobin estimation every 3 months are used to monitor glycemic control in children. Recently, ambulatory glucose profile (AGP) is increasingly being used to study the glycemic patterns in adults. However, accuracy and reliability of AGP in children have not been evaluated yet...
September 2016: Indian Journal of Endocrinology and Metabolism
Asma Deeb, Nabras Al Qahtani, Salima Attia, Hana Al Suwaidi, Nico Nagelkerke
BACKGROUND: Ramadan fasting by patients with type 1 diabetes might predispose them to hypoglycemia. There are no data on the optimal way of adjusting basal insulin during fasting. We aim at studying whether reducing basal insulin during Ramadan reduces the frequency of symptomatic hypoglycemia. METHODS: We enrolled children and adolescents with type 1 diabetes who intended to fast during Ramadan. Logbooks were given to subjects to mark days fasted, symptomatic hypoglycemia, and dose of basal insulin on all days of Ramadan...
September 2016: Diabetes Technology & Therapeutics
Guizhen Qiu, Wei Tian, Mei Huan, Jinlong Chen, Haitao Fu
The aim of this study was to investigate the anti-hyperglycemic activity and mechanism of formononetin in alloxan-induced type 1 diabetic mice by determining its effect on some diabetes-related indices as described below. Body weight, fasting blood glucose, hepatic glycogen, serum insulin, and serum glucagon were determined by electronic scales, glucometer, and ELISA kits. Fas, Caspase-3, pancreatic and duodenal homeobox-1 , insulin receptor substrate 2, glucokinase and glucose transporter 2, mRNA and proteins levels in pancreas tissue, and glucokinase and glucose-6-phosphatase mRNA, and proteins levels in liver tissue were detected by fluorogenic quantitative-polymerase chain reaction and Western blot assays...
July 13, 2016: Experimental Biology and Medicine
Shine Stephen, Meenakshi Agnihotri, Sukhpal Kaur
Insulin has been used in wound healing to increase wound collagen, granulation tissue, wound tensile strength, and local production of insulin-like growth factors by fibroblasts. Saline is a widely used irrigating and wound dressing solution. Patients admitted to an acute care facility who had a Grade 2 or Grade 3 pressure ulcer were recruited to participate in a randomized, controlled trial to compare the effect of normal saline-impregnated gauze and insulin dressing in pressure ulcer healing. Persons with immunodeficiency, diabetes mellitus, pregnancy, osteomyelitis, and peripheral vascular illness were not eligible for the study...
June 2016: Ostomy/wound Management
Ashley Pinckney, Mark R Rigby, Lynette Keyes-Elstein, Carol L Soppe, Gerald T Nepom, Mario R Ehlers
PURPOSE: In natural history studies, maintenance of higher levels of C-peptide secretion (a measure of endogenous insulin production) correlates with a lower incidence of major hypoglycemic events in patients with type 1 diabetes mellitus (T1D), but it is unclear whether this is also true for drug-induced C-peptide preservation. METHODS: We analyzed hypoglycemic events and glycemic control data from the T1DAL (Inducing Remission in New-Onset T1D with Alefacept) study, a trial of alefacept in new-onset T1D, which found significant C-peptide preservation at 1 and 2 years...
June 2016: Clinical Therapeutics
Swetha Chandru, Prashant Vishwanath, Devananda Devegowda, Suresha Nagaraja Ramasamudra, Akila Prashant, Basavanagowdappa Hathur
INTRODUCTION: The present study was taken up to compare and evaluate the effect of Momordica charantia supplementation with pioglitazone on PKC-β and PPAR-γ activity in kidneys of diabetic rats. The hypoglycaemic and lipid lowering effect of Momordica charantia were screened in laboratory animal model and its potency was compared with a Thiazolidinedione (TZD) group antidiabetic drug like pioglitazone. MATERIALS AND METHODS: Adult healthy albino rats of Wistar strain aged 3-4months, weighing between 170-250gm of either sex were divided into 4 groups; Group 1 (normal controls), Group 2 (diabetic controls), Group 3 (diabetic rats treated with pioglitazone) and Group 4 (diabetic rats treated with bitter melon juice)...
April 2016: Journal of Clinical and Diagnostic Research: JCDR
Eun Ky Kim, Soo Heon Kwak, Seungsu Baek, Seung Lyeol Lee, Hak Chul Jang, Kyong Soo Park, Young Min Cho
BACKGROUND: We developed a patient-centered, smartphone-based, diabetes care system (PSDCS). This study aims to test the feasibility of glycosylated hemoglobin (HbA1c) reduction with the PSDCS. METHODS: This study was a single-arm pilot study. The participants with type 2 diabetes mellitus were instructed to use the PSDCS, which integrates a Bluetooth-connected glucometer, digital food diary, and wearable physical activity monitoring device. The primary end point was the change in HbA1c from baseline after a 12-week intervention...
June 2016: Diabetes & Metabolism Journal
Ryan J McDonough, Mark A Clements, Stephen A DeLurgio, Susana R Patton
BACKGROUND: Adherence to the type 1 diabetes (T1D) regimen, while predictive of glycemic control, decreases during adolescence. For adolescents, attaining adequate sleep is an additional challenge. This study evaluates the impact of sleep on adherence in teens with T1D. SUBJECTS: Forty-five adolescents aged 12-18 yr, with T1D for at least 6 months while on insulin pump therapy. METHODS: Adolescents logged their sleep on a written diary for 2 wk...
March 30, 2016: Pediatric Diabetes
Allison C Sylvetsky, Radha Nandagopal, Tammy T Nguyen, Marisa R Abegg, Mahathi Nagarur, Paul Kaplowitz, Kristina I Rother
AIM: To investigate whether assigning young, healthy and motivated lay volunteer partners ("buddies") to adolescents with type 2 diabetes improves hemoglobin A1c (HbA1c). METHODS: Adolescents with type 2 diabetes were randomized to partnering with a "buddy" or to conventional treatment. During the initial screening visit, which coincided with a routine outpatient diabetes clinic visit, patients with type 2 diabetes underwent a physical examination, detailed medical history, laboratory measurement of HbA1c, and completed two questionnaires (Pediatric Quality of Life Inventory and Children's Depression Inventory) to assess their overall quality of life and the presence of depressive symptoms...
December 25, 2015: World Journal of Diabetes
Susana R Patton, Stephen A DeLurgio, Mark A Clements
OBJECTIVE: The Average Daily Risk Range (ADRR) is a measure of glycemic variability (GV) developed for adults with diabetes. Although the ADRR is increasingly being reported in pediatric diabetes research and may also be used in clinical management, it has never been examined for its sensitivity to predicting hyper- and hypoglycemia in youths or compared for its predictive ability with other measures of GV in youths. Thus, we present predictive validity data for the ADRR in youths with type 1 diabetes...
November 2015: Diabetes Technology & Therapeutics
Lin Ding, Zhiping Qu, Jinfeng Chi, Rui Shi, Lulu Wang, Lulu Hou, Yan Wang, Shuguang Pang
OBJECTIVE: This study was designed to investigate the effects of metformin on bile acid in type 2 diabetes mellitus (T2DM). METHODS: In this study, we constructed a model of T2DM by a combination of high-fat diet (HFD) and low dose of streptozotocin (STZ) intraperitoneal injection. Blood samples by tail vein and eye angular vein were withdrawn before (time 0) and 30, 60, and 120 minutes after administration of glucose before STZ injection and once a week after diabetes induction, and were analyzed to evaluate the level of the fasting blood glucose and fasting insulin using glucometer...
2015: International Journal of Clinical and Experimental Pathology
Viviane F A Van Casteren, Nathalie H E Bossuyt, Sarah J S Moreels, Geert Goderis, Katrien Vanthomme, Johan Wens, Etienne W De Clercq
BACKGROUND: The Belgian care trajectory (CT) for diabetes mellitus type 2 (T2DM), implemented in September 2009, aims at providing integrated, evidence-based, multidisciplinary patient- centred care, based on the chronic care model. The research project ACHIL (Ambulatory Care Health Information Laboratory) studied the adherence of CT patients, in the early phases of CT programme implementation, with CT obligations, their uptake of incentives for self-management, whether the CT programme was targeting the appropriate group of patients, how care processes for these patients evolved over time and whether CT start led to better quality in the processes and outcomes of care...
2015: Archives of Public Health, Archives Belges de Santé Publique
Sanjay Basu, Christopher Millett, Sandeep Vijan, Rodney A Hayward, Sanjay Kinra, Rahoul Ahuja, John S Yudkin
BACKGROUND: Like a growing number of rapidly developing countries, India has begun to develop a system for large-scale community-based screening for diabetes. We sought to identify the implications of using alternative screening instruments to detect people with undiagnosed type 2 diabetes among diverse populations across India. METHODS AND FINDINGS: We developed and validated a microsimulation model that incorporated data from 58 studies from across the country into a nationally representative sample of Indians aged 25-65 y old...
May 2015: PLoS Medicine
Soo Lim, Seon Mee Kang, Kyoung Min Kim, Jae Hoon Moon, Sung Hee Choi, Hee Hwang, Hye Seung Jung, Kyong Soo Park, Jun Oh Ryu, Hak Chul Jang
AIMS: In 2011, we demonstrated that an individualized health management system employing advanced medical information technology, designated ubiquitous (u)-healthcare, was helpful in achieving glycemic control without hypoglycemia in patients with diabetes. Following this, we generated a new multidisciplinary u-healthcare system by upgrading our clinical decision support system (CDSS) rule engine and integrating a physical activity-monitoring device and dietary feedback into a comprehensive package...
April 2016: Acta Diabetologica
L A Horovskaia, T V Lobachevskaia, O V Chernichuk
The modern laboratory medicine provides observation of requirements to glucometers in line with standard DIN EN ISO 15197-2:2013 for self-control under treatment of patients with diabetes mellitus and registration of biologic types data. The study compared functioning of diagnostic devices in point-of-care of four manufacturers. The samples of whole blood taken from two patients were analyzed in three lots of test-strips with concentration of glucose 4.5 and 11.8 mmol/l using glucometers Accu-Chek Active, One Touch Select, Sattelite Express and Contour TS and reference analyzer Olympus AU 400...
January 2015: Klinicheskaia Laboratornaia Diagnostika
Taofeek Oluwole Awotidebe, Rufus Adesoji Adedoyin, Abraar Olalakan Yusuf, Chidozie Emmanuel Mbada, Rose Opiyo, Frasier Chidyaonga Maseko
INTRODUCTION: Functional Exercise Capacity (FEC) is a valid measure of physical fitness in health and disease. However, there is paucity of studies on FEC in African patients with Type-2 Diabetes (T2D). This study compared FEC between patients with T2D and healthy controls. METHODS: Thirty five patients with T2D (18 men, 17 women) and 35 (16 men, 19 women) age-sex matched healthy controls participated in this case-control study. Anthropometric and demographic characteristics and cardiovascular parameters were measured following standard procedures...
2014: Pan African Medical Journal
Alfonso Soto González, Niurka Quintela Fernández, Alfonso Pumar López, Ricardo Darias Garzón, Margarita Rivas Fernández, Gloria Barberá Comes
OBJECTIVE: To assess the relationship between metabolic control (MC) and frequency of self-monitoring of blood glucose (SMBG) in insulin-treated patients with type 1 (T1DM) and type 2 (T2DM) diabetes mellitus, and to analyze the factors associated to MC. MATERIAL AND METHODS: A multicenter, cross-sectional, observational study was conducted in which endocrinologists enrolled diabetic patients treated with insulin who used a glucometer. The cut-off value for MC was HbA1c ≤ 7%...
May 2015: Endocrinología y Nutrición: órgano de la Sociedad Española de Endocrinología y Nutrición
Verónica Sambra Vásquez, Carolina Tapia Fernández, Claudia Vega Soto
INTRODUCTION: Currently there is no consensus regarding fragmentation, quantity and quality of carbohydrates (CHO) that should be followed by insulin treated type 2 diabetic individuals (ITT2D). OBJECTIVE: To determine the relationship between the meal times, quality of available CHO in every meal and the metabolic control parameters in ITT2D individuals with a single or double dose of intermediate-acting insulin. METHODS: 40 ITT2D individuals were evaluated, using food surveys to obtain the quantity of CHO, glycemic index (GI), glycemic load (GL) in every meal and meal times...
2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
Rudolf Chlup, Jan Krejci, Mark O'Connell, Blanka Sebestova, Robert Plicka, Lucie Jezova, Tereza Brozova, Blanka Doubravova, Hana Zalesakova, Emilia Durajkova, Jiri Vojtek, Josef Bartek
AIM: The aim of this pilot study was to acquire insight into the parameters of glycaemic control, especially, (1) the time delay (lag phase) between plasma and tissue glucose concentrations in relation to rise and fall in glucose levels and (2) the rate of glucose increase and decrease. METHODS: Four healthy people (HP), 4 people with type 1diabetes (DM1) and 4 with type 2 diabetes (DM2) underwent concurrent glucose measurements by means of (1) the continuous glucose monitoring system (CGMS-Medtronic), Medtronic-Minimed, CA, USA, calibrated by the glucometer Calla, Wellion, Austria, and, (2) the Beckman II analyser to measure glucose concentrations in venous plasma...
December 2015: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
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