keyword
MENU ▼
Read by QxMD icon Read
search

Framingham

keyword
https://www.readbyqxmd.com/read/29676517/impact-of-changes-in-inflammation-on-estimated-10-year-cardiovascular-risk-in-rheumatoid-arthritis
#1
Zhi Yu, Nicole Yang, Brendan M Everett, Michelle Frits, Christine Iannaccone, Jonathan Coblyn, Michael Weinblatt, Nancy Shadick, Daniel H Solomon, Katherine P Liao
BACKGROUND: Validated cardiovascular (CV) risk estimates were developed in populations with relatively stable inflammatory levels. In rheumatoid arthritis (RA), patients routinely experience significant changes in inflammation. We tested whether changes in inflammation impact estimated CV risk as measured using validated population-based risk calculators. METHODS: We studied participants in a prospective RA cohort. We included participants who experienced a decrease (CRP decrease group) or increase (CRP increase group) of ≥10mg/L in C-reactive protein (CRP) at 2 consecutive time points, 1 year apart...
April 20, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29675098/baseline-metabolic-risk-score-and-postsurgical-esophageal-cancer-specific-mortality-the-fujian-prospective-investigation-of-cancer-fiesta-study
#2
Hong Sha, Dan Hu, Sinan Wu, Feng Peng, Guodong Xu, Guohui Fan, Xiandong Lin, Gang Chen, Binying Liang, Ying Chen, Chao Li, Hejun Zhang, Yan Xia, Jinxiu Lin, Xiongwei Zheng, Wenquan Niu
Backgrounds : Compelling evidence has emerged to support a close relationship between metabolic syndrome and esophageal cancer (EC). Aims : Using five baseline metabolism-related markers, we constructed a metabolic risk score (MRS), aiming to test whether MRS can improve the prediction of postsurgical EC-specific mortality over traditional demographic and clinicopathologic characteristics. Methods : Total 2535 EC patients who received three-field lymphadenectomy were enrolled from January 2000 to December 2010, and they were followed up until December 2015...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29674390/consumption-of-sugars-sugary-foods-and-sugary-beverages-in-relation-to-adiposity-related-cancer-risk-in-the-framingham-offspring-cohort-1991-2013
#3
Nour Makarem, Elisa V Bandera, Yong Lin, Paul Jacques, Richard B Hayes, Niyati Parekh
BACKGROUND: Higher sugar consumption may increase cancer risk by promoting insulin-glucose dysregulation, oxidative stress, hormonal imbalances, and excess adiposity. This prospective study investigates the association between dietary sugars(fructose and sucrose) and sugary foods and beverages in relation to combined and site-specific (breast, prostate, colorectal) adiposity-associated cancers. METHODS: The analytic sample consisted of 3,184 adults, aged 26-84y, from the Framingham Offspring cohort...
April 19, 2018: Cancer Prevention Research
https://www.readbyqxmd.com/read/29672210/prognostic-utility-of-stress-testing-and-cardiac-biomarkers-in-menopausal-women-at-low-to-intermediate-risk-for-coronary-artery-disease-smart-study-5-year-outcome
#4
Sahar S Abdelmoneim, Caroline A Ball, Francesca Mantovani, Mary E Hagen, Susan Eifert-Rain, Susan Wilansky, Ramon Castello, Patricia A Pellikka, Patricia J M Best, Sharon L Mulvagh
BACKGROUND: In women with low to intermediate risk of coronary artery disease (CAD), prognostic detection strategies have been controversial. We present the follow-up data of the SMART trial in peri/postmenopausal women at low to intermediate risk of CAD. OBJECTIVES: To determine the value of contrast stress echocardiography (CSE), stress electrocardiogram (sECG), and serum biomarkers for prediction of cardiovascular events (CE) in peri/postmenopausal women at low to intermediate risk of CAD...
April 19, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29671956/atherosclerosis-and-autoimmunity-a-growing-relationship
#5
REVIEW
Maryam Sanjadi, Ziba Rezvanie Sichanie, Hamidreza Totonchi, Jafar Karami, Ramazan Rezaei, Saeed Aslani
Atherosclerosis is regarded as one of the leading causes of mortality and morbidity in the world. Nowadays, it seems that atherosclerosis cannot be defined merely through the Framingham traditional risk factors and that autoimmunity settings exert a remarkable role in its mechanobiology. Individuals with autoimmune disorders show enhanced occurrence of cardiovascular complications and subclinical atherosclerosis. The mechanisms underlying the atherosclerosis in disorders like rheumatoid arthritis, systemic lupus erythematosus, antiphospholipid syndrome, systemic sclerosis and Sjögren's syndrome, seem to be the classical risk factors...
April 19, 2018: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/29670914/association-of-wrist-circumference-and-waist-to-height-ratio-with-cardiometabolic-risk-factors-among-type-ii-diabetics-in-a-ghanaian-population
#6
Christian Obirikorang, Yaa Obirikorang, Emmanuel Acheampong, Enoch Odame Anto, Emmanuel Toboh, Evans Adu Asamoah, Bright Amakwaa, Emmanuella Nsenbah Batu, Peter Brenya
The study determined the association of wrist circumference (WrC) and waist-to-height ratio (WHtR) with cardiometabolic risk factors among diabetics in a Ghanaian population. This cross-sectional study involved 384 diabetic patients at Begoro District Hospital, Ghana. Blood pressure, anthropometrics, and biochemical indices were measured. The overall prevalence of dyslipidaemia, metabolic syndrome (MetS), and hypertension was 42.4%, 76.3%, and 39.8%, respectively. The optimum cut-off range of WrC to identify individuals at increased cardiometabolic risk was 17...
2018: Journal of Diabetes Research
https://www.readbyqxmd.com/read/29669944/neutrophil-subsets-and-their-gene-signature-associate-with-vascular-inflammation-and-coronary-atherosclerosis-in-lupus
#7
Philip M Carlucci, Monica M Purmalek, Amit K Dey, Yenealem Temesgen-Oyelakin, Simantini Sakhardande, Aditya A Joshi, Joseph B Lerman, Alice Fike, Michael Davis, Jonathan H Chung, Martin P Playford, Mohammad Naqi, Pragnesh Mistry, Gustavo Gutierrez-Cruz, Stefania Dell'Orso, Faiza Naz, Taufiq Salahuddin, Balaji Natarajan, Zerai Manna, Wanxia L Tsai, Sarthak Gupta, Peter Grayson, Heather Teague, Marcus Y Chen, Hong-Wei Sun, Sarfaraz Hasni, Nehal N Mehta, Mariana J Kaplan
BACKGROUND: Systemic lupus erythematosus (SLE) is associated with enhanced risk of atherosclerotic cardiovascular disease not explained by Framingham risk score (FRS). Immune dysregulation associated to a distinct subset of lupus proinflammatory neutrophils (low density granulocytes; LDGs) may play key roles in conferring enhanced CV risk. This study assessed if lupus LDGs are associated with in vivo vascular dysfunction and inflammation and coronary plaque. METHODS: SLE subjects and healthy controls underwent multimodal phenotyping of vascular disease by quantifying vascular inflammation (18F-fluorodeoxyglucose-PET/CT [18F-FDG-PET/CT]), arterial dysfunction (EndoPAT and cardio-ankle vascular index), and coronary plaque burden (coronary CT angiography)...
April 19, 2018: JCI Insight
https://www.readbyqxmd.com/read/29669105/are-trends-in-dementia-incidence-associated-with-compression-in-morbidity-evidence-from-the-framingham-heart-study
#8
Carole Dufouil, Alexa Beiser, Geneviève Chêne, Sudha Seshadri
Objectives: Several epidemiological studies suggest declining trends in dementia over the last three decades with both decreasing age-specific prevalence and incidence. There is limited data on whether this delayed clinical onset is accompanied by a shorter postdiagnosis survival. Methods: A total of 5,205 participants from the Framingham Original and Offspring cohorts were studied. Four epochs were considered from 1977-1984 to 2004-2008. Gender and education adjusted 5-year mortality risks were estimated using delayed entry Cox models with the earliest epoch as reference category...
April 16, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29667200/treatment-in-a-preventive-cardiology-clinic-utilizing-advanced-practice-providers-apps-effectively-closes-atherosclerotic-cardiovascular-disease-ascvd-risk-management-gaps-amongst-a-primary-prevention-population-compared-with-a-propensity-matched-primary-care
#9
Emilio Fentanes, Anthony G Vande Hei, R Scott Holuby, Norma Suarez, Yousif Slim, Jennifer N Slim, Ahmad M Slim, Dustin Thomas
BACKGROUND: Advanced Practice Providers (APPs) can fill access to care gaps created by physician shortages and improve adherence/compliance with preventive atherosclerotic cardiovascular disease (ASCVD) interventions. METHODS: We retrospectively reviewed data on 595 patients enrolled in a preventive cardiology clinic (PCC) utilizing APPs compared with a propensity-matched cohort (PMC) of 595 patients enrolled in primary care clinics alone. PCC patients were risk stratified using Framingham risk scoring (FRS) and coronary artery calcium scoring (CACS) and treated based on published guideline-based algorithms...
April 17, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29665562/10-year-cvd-risk-in-han-chinese-mainland-patients-with-schizophrenia
#10
Shuai Zhao, HaiLong Xia, JingJing Mu, Long Wang, Li Zhu, AnZhen Wang, XiaoQin Zhou
People with schizophrenia have a shortened life expectancy, with cardiovascular disease (CVD) being the primary contributor to this excessive mortality. A total of 466 inpatients with schizophrenia and 507 healthy community controls in the Chinese mainland were recruited in this study. Sociodemographic information, medical history, and smoking history were recorded. In addition, total cholesterol (TC), fasting blood glucose (FBG), triglycerides (TG), and high-destiny lipoprotein cholesterol (HDL-C) were analyzed...
April 9, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29660603/both-alcoholic-and-non-alcoholic-steatohepatitis-association-with-cardiovascular-risk-and-liver-fibrosis
#11
Beatriz A Sánchez-Jiménez, Diana Brizuela-Alcántara, Martha H Ramos-Ostos, Luis F Alva-López, Misael Uribe-Esquivel, Norberto C Chávez-Tapia
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of liver disease worldwide. Mortality in NAFLD is mainly related to cardiovascular disease (CVD) and cancer. NAFLD and its association with both CVD and liver disease risk have been well evaluated, but the association of NAFLD with alcohol, known as "both alcoholic and non-alcoholic steatohepatitis" (BASH), remains uncertain. The objective of this study was to assess the influence of alcohol and obesity in the development of liver and cardiovascular disease risk...
November 15, 2017: Alcohol
https://www.readbyqxmd.com/read/29659657/prognostic-value-of-electrocardiographic-left-ventricular-hypertrophy-on-cardiovascular-risk-in-a-non-hypertensive-community-based-population
#12
Kentaro Tanaka, Fumitaka Tanaka, Toshiyuki Onoda, Kozo Tanno, Masaki Ohsawa, Kiyomi Sakata, Shinichi Omama, Kuniaki Ogasawara, Yasuhiro Ishibashi, Kazuyoshi Itai, Toru Kuribayashi, Akira Okayama, Motoyuki Nakamura
BACKGROUND: The appearance of left ventricular hypertrophy on 12-lead electrocardiography (ECG-LVH) has been clarified to be associated with the risk of incidence of cardiovascular events (CVEs) in hypertensive individuals and the general population, but not enough in non-hypertensive individuals. METHODS: A total of 4,927 non-hypertensive individuals ≥ 40 years of age who were free of CVE in the general population were followed for the incidence of CVE. ECG-LVH was defined according to criteria of the Sokolow-Lyon (SL) voltage, Cornell voltage (CV), or Cornell voltage product (CP)...
April 6, 2018: American Journal of Hypertension
https://www.readbyqxmd.com/read/29658833/gonadopenia-and-aging-in-men
#13
Sandeep Singh Dhindsa, Michael S Irwig, Kathleen Wyne
OBJECTIVE: The decrease in testosterone levels that occurs with aging has become an important clinical issue both due to the growth of the geriatric population and patient interest in testosterone therapy. The decision to assess for testosterone deficiency and the ability to determine whether the benefits exceed the risks require a comprehensive evaluation of the aging patient. This article is part of a series of papers focused on the endocrinology of aging. This review addresses common issues needed for clinical decision making, including how to interpret test results, differential diagnosis, potential impact of testosterone treatment on insulin resistance and cardiovascular disease, and options for therapy...
April 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29657148/the-prevalence-of-renal-impairment-in-patients-with-spondyloarthritis-results-from-the-international-asas-comospa-study
#14
Marion Couderc, Bruno Pereira, Anna Molto, Aurélien Tiple, Martin Soubrier, Maxime Dougados
OBJECTIVE: To assess the prevalence and association of renal dysfunction in patients with spondyloarthritis (SpA). METHODS: The ASAS-COMOSPA (Assessment of Spondyloarthritis international Society-COMOrbidities in SPondyloArthritis) was an international study (22 participating countries from 4 continents) investigating comorbidities in SpA. Renal function was assessed based on estimated glomerular filtration rate (eGFR) calculated using the Modification of Diet in Renal Disease equation...
April 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29657043/endothelial-dysfunction-abnormal-vascular-structure-and-lower-urinary-tract-symptoms-in-men-and-women
#15
Shogo Matsui, Masato Kajikawa, Tatsuya Maruhashi, Yumiko Iwamoto, Nozomu Oda, Shinji Kishimoto, Haruki Hashimoto, Takayuki Hidaka, Yasuki Kihara, Kazuaki Chayama, Eisuke Hida, Chikara Goto, Yoshiki Aibara, Ayumu Nakashima, Farina Mohamad Yusoff, Kensuke Noma, Yoshitaka Kuwahara, Akio Matsubara, Yukihito Higashi
BACKGROUND: Lower urinary tract symptoms (LUTS) is not only common symptoms in elderly men and women but also risk of future cardiovascular events. The purpose of this study was to evaluate the relationships of vascular function and structure with LUTS in men and women. METHODS: We investigated flow-mediated vasodilation (FMD) and nitroglycerine-induced vasodilation (NID) as vascular function, brachial-ankle pulse wave velocity (baPWV) as vascular structure, and LUTS assessed by International Prostate Symptom Score (IPSS) in 287 men and 147 women...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29656956/ultrasound-assessed-visceral-fat-and-associations-with-glucose-homeostasis-and-cardiovascular-risk-in-clinical-practice
#16
M Bellan, M Menegatti, C Ferrari, G P Carnevale Schianca, M Pirisi
BACKGROUND AND AIMS: Despite the lack of evidence that assessing the global cardiovascular risk leads to a decreased incidence of cardiovascular events, accurate patient profiling is paramount in preventive medicine. An excess of visceral fat (VF) is associated with an enhanced cardiovascular risk; importantly, VF is quantifiable rapidly, cheaply and safely by ultrasound, which makes it suitable for use in clinical practice. In the present study, we aimed to evaluate if US-measured VF (USVF) could be a better predictor of glucose homeostasis and cardiovascular risk than simple anthropometric measures...
February 2, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29656848/the-discipline-of-epidemiology-engaging-in-the-full-breadth-of-population-health-science
#17
EDITORIAL
Harold I Feldman
This address was delivered by Harold I. Feldman, MD, MSCE, at the Annual Meeting of the American College of Epidemiology in New Orleans, Louisiana, on September 26, 2017. Dr. Feldman is George S. Pepper Professor of Public Health and Preventive Medicine, Professor of Epidemiology and Medicine, and Chair, Department of Biostatistics, Epidemiology, and Informatics at the Perelman School of Medicine at the University of Pennsylvania. He is recognized nationally and internationally for his expertise in kidney disease epidemiology...
March 21, 2018: Annals of Epidemiology
https://www.readbyqxmd.com/read/29656781/observational-and-genetic-associations-of-resting-heart-rate-with-aortic-valve-calcium
#18
Seamus P Whelton, Andreas C Mauer, Karol M Pencina, Joseph M Massaro, Ralph B D'Agostino, Caroline S Fox, Udo Hoffmann, Erin D Michos, Gina M Peloso, Line Dufresne, James C Engert, Sekar Kathiresan, Matthew Budoff, Wendy S Post, George Thanassoulis, Christopher J O'Donnell
It is unknown if lifelong exposure to increased hemodynamic stress from an elevated resting heart rate (HR) may contribute to aortic valve calcium (AVC). We performed multivariate regression analyses using data from 1,266 Framingham Heart Study (FHS) Offspring cohort participants and 6,764 Multi-Ethnic Study of Atherosclerosis (MESA) participants. We constructed a genetic risk score (GRS) for HR using summary-level data in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) AVC Consortium to investigate if there was evidence in favor of a causal relation...
February 13, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29652918/a-genome-wide-association-study-of-red-blood-cell-fatty-acids-and-ratios-incorporating-dietary-covariates-framingham-heart-study-offspring-cohort
#19
Anya Kalsbeek, Jenna Veenstra, Jason Westra, Craig Disselkoen, Kristin Koch, Katelyn A McKenzie, Jacob O'Bott, Jason Vander Woude, Karen Fischer, Greg C Shearer, William S Harris, Nathan L Tintle
Recent analyses have suggested a strong heritable component to circulating fatty acid (FA) levels; however, only a limited number of genes have been identified which associate with FA levels. In order to expand upon a previous genome wide association study done on participants in the Framingham Heart Study Offspring Cohort and FA levels, we used data from 2,400 of these individuals for whom red blood cell FA profiles, dietary information and genotypes are available, and then conducted a genome-wide evaluation of potential genetic variants associated with 22 FAs and 15 FA ratios, after adjusting for relevant dietary covariates...
2018: PloS One
https://www.readbyqxmd.com/read/29652762/distribution-and-performance-of-cardiovascular-risk-scores-in-a-mixed-population-of-hiv-infected-and-community-based-hiv-uninfected-individuals-in-uganda
#20
Anthony N Muiru, Prossy Bibangambah, Linda Hemphill, Ruth Sentongo, June-Ho Kim, Virginia A Triant, David R Bangsberg, Alexander C Tsai, Jeffrey N Martin, Jessica E Haberer, Yap Boum, Jorge Plutzky, Peter W Hunt, Samson Okello, Mark J Siedner
BACKGROUND: The utility and validity of CVD risk scores are not well-studied in sub-Saharan Africa. We compared and correlated CVD risk scores with carotid intima media thickness (c-IMT) among HIV-infected and uninfected people in Uganda. METHODS: We first calculated CVD risk using the 1) Framingham laboratory-based score; 2) Framingham non-laboratory score (FRS-BMI); 3) Reynolds risk score; 4) American College of Cardiology and American Heart Association score; and 5) the Data-collection on Adverse Effects of Anti-HIV Drugs score...
April 11, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
keyword
keyword
67987
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"