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https://www.readbyqxmd.com/read/28926157/evaluation-of-a-palliative-and-hospice-care-telephone-hotline-for-severely-affected-multiple-sclerosis-patients-and-their-caregivers
#1
Julia Strupp, Bernadette Groebe, Andrea Knies, Michaela Mai, Raymond Voltz, Heidrun Golla
BACKGROUND: Palliative and hospice care (PHC) still highly focus on cancer patients. OBJECTIVES: To connect severely affected Multiple Sclerosis (MS) patients and caregivers to PHC, a nationwide hotline was implemented facilitating access to PHC. METHODS: The hotline was designed in cooperation with the German Multiple Sclerosis Society. Self-disclosed information given by callers was documented using case report forms supplemented by personal notes...
September 19, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/28905724/position-statement-functionally-appropriate-nonhuman-primate-environments-as-an-alternative-to-the-term-ethologically-appropriate-environments
#2
Mollie A Bloomsmith, John Hasenau, Rudolf P Bohm
The American Society of Primatologists (ASP), the Association of Primate Veterinarians (APV), and the American College of Laboratory Animal Medicine (ACLAM) have come together to develop this position statement in which the term "functionally appropriate nonhuman primate environments" is proposed as a better descriptor and as an alternative to the previously used term, "ethologically appropriate environments" to describe environments that are suitable for nonhuman primates involved in biomedical research. In 2015, the United States Department of Agriculture requested comments on a petition which called for amending the Animal Welfare Act so that all research primates would be housed in "ethologically appropriate physical and social environments...
January 1, 2017: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/28889043/photovoicing-the-neighbourhood-understanding-the-situated-meaning-of-intangible-places-for-ageing-in-place
#3
Susan van Hees, Klasien Horstman, Maria Jansen, Dirk Ruwaard
Ageing-in-place is considered important for the health of older adults. In this paper, inspired by a constructivist approach to ageing-in-place, we unravel professionals' and older adults' constructions of ageing-in-place. Their perspectives are studied in relation to a policy that aims to develop so-called 'lifecycle-robust neighbourhoods' in the southern part of the Netherlands. We conducted a photovoice study in which 18 older adults (70-85 years) living independently and 14 professionals (social workers, housing consultants, neighbourhood managers and community workers) were asked to photograph and discuss the places they consider important for ageing-in-place...
September 7, 2017: Health & Place
https://www.readbyqxmd.com/read/28860432/-maggie-s-tokyo-s-human-support-the-meaning-of-where-now-and-cancer-journey
#4
Yoshie Takada
The landscape architect Maggie Jencks felt that she wanted a place to "get herself back" when her breast cancer recurred and was told that she only had a few months remaining. Mr. Charles Jencks, her husband who fulfilled her wishes, opened the first "Maggie's Cancer Caring Centre" in Edinburgh in 1996. Masako Akiyama, the chief of Maggie's Tokyo found out about Maggie's Centre when she listened to a presentation from Andrew Anderson, the director of Maggie's Edinburgh, at an International Nursing Seminar in 2008...
August 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28859583/relationship-between-psychiatric-service-consumers-and-providers-goal-concordance-and-consumers-personal-goal-attainment
#5
Efrat Shadmi, Marc Gelkopf, Paula Garber-Epstein, Vered Baloush-Kleinman, Ronit Dudai, Silvia Lea Scialom, David Roe
OBJECTIVE: This study tested concordance between consumers' and providers' reports of personal goal setting and its relationship to self-reported goal attainment. METHODS: Data are from the Israeli Psychiatric Rehabilitation Patient Reported Outcome Measurement project. Consumers (N=2,885) and the providers who were most knowledgeable about their care indicated two domains from a list of ten in which consumers had set goals during the previous year. Consumers reported on goal attainment in each domain...
September 1, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28853532/-notes-from-a-six-months-volunteer-mission-as-medical-staff-in-a-district-hospital-in-uganda
#6
Reut Harel, Eitan Miron, Ronen Stoff, Yahel Segal
In December 2014 my husband and I flew for a stay of six months in Uganda. We went there in order to volunteer in the district hospital of Kiboga, one of the most impoverished districts of this poverty stricken country. A district in which over 60% of the population lives off less than a dollar and twenty five cents a day, in which the average life expectancy is 46.7 years (9.1 years lower than the national average expectancy). Kiboga's district hospital serves the 300,000 residents of the district, of whom 20,000 live in the district capital, while the rest are mainly farmers and cattle keepers, scattered in small villages that have limited and weather-dependent access...
August 2017: Harefuah
https://www.readbyqxmd.com/read/28839344/methodological-pluralism-and-mixed-methodology-to-strengthen-community-psychology-research-an-example-from-oxford-house
#7
Emily M May, Bronwyn A Hunter, Leonard A Jason
This article evaluates how a plurality of research methods has served a research program that has functioned in a much-needed area of research: the role of housing and recovery residences in addiction recovery. The review focuses on one mutually supportive recovery residence model, called Oxford House, which represents more than 1,700 democratic, self-governing residences. To date, there has been no comprehensive evaluation of the research methods used with Oxford House or any other recovery residence. In this article, research methods, including study designs and data analyses, are summarized for 114 peer-reviewed empirical studies that included data on Oxford Houses or Oxford House residents...
January 2017: Journal of Community Psychology
https://www.readbyqxmd.com/read/28834470/man-versus-nature-also-sprach-zarathustra-and-an-end-of-life-house-call
#8
Maxwell M Krem
Tom has been my patient since my fellowship, and now he is dying. He has been a constant in my career journey as much as I have been in his treatment, for 5 years and more than 80 treatment cycles. As an oncology fellow, I told him of his diagnosis of colon cancer with lung and liver metastases. I..
August 24, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28814459/the-virtual-house-call-a-21st-century-innovation-in-the-care-of-patients-with-parkinson-disease
#9
EDITORIAL
David R Shprecher, Jennifer J Majersik
No abstract text is available yet for this article.
August 16, 2017: Neurology
https://www.readbyqxmd.com/read/28814455/national-randomized-controlled-trial-of-virtual-house-calls-for-parkinson-disease
#10
RANDOMIZED CONTROLLED TRIAL
Christopher A Beck, Denise B Beran, Kevin M Biglan, Cynthia M Boyd, E Ray Dorsey, Peter N Schmidt, Richard Simone, Allison W Willis, Nicholas B Galifianakis, Maya Katz, Caroline M Tanner, Kristen Dodenhoff, Jason Aldred, Julie Carter, Andrew Fraser, Joohi Jimenez-Shahed, Christine Hunter, Meredith Spindler, Suzanne Reichwein, Zoltan Mari, Becky Dunlop, John C Morgan, Dedi McLane, Patrick Hickey, Lisa Gauger, Irene Hegeman Richard, Nicte I Mejia, Grace Bwala, Martha Nance, Ludy C Shih, Carlos Singer, Silvia Vargas-Parra, Cindy Zadikoff, Natalia Okon, Andrew Feigin, Jean Ayan, Christina Vaughan, Rajesh Pahwa, Rohit Dhall, Anhar Hassan, Steven DeMello, Sara S Riggare, Paul Wicks, Meredith A Achey, Molly J Elson, Steven Goldenthal, H Tait Keenan, Ryan Korn, Heidi Schwarz, Saloni Sharma, E Anna Stevenson, William Zhu
OBJECTIVE: To determine whether providing remote neurologic care into the homes of people with Parkinson disease (PD) is feasible, beneficial, and valuable. METHODS: In a 1-year randomized controlled trial, we compared usual care to usual care supplemented by 4 virtual visits via video conferencing from a remote specialist into patients' homes. Primary outcome measures were feasibility, as measured by the proportion who completed at least one virtual visit and the proportion of virtual visits completed on time; and efficacy, as measured by the change in the Parkinson's Disease Questionnaire-39, a quality of life scale...
September 12, 2017: Neurology
https://www.readbyqxmd.com/read/28813151/the-medicinal-and-biological-chemistry-mbc-library-an-efficient-source-on-new-hits
#11
Víctor Sebastián Pérez, Carlos Roca, Mahendra Awale, Jean-Louis Reymond, Ana Martínez, Carmen Gil, Nuria E Campillo
Identification of new hits is one of the biggest challenges in drug discovery. Creating a library of well-characterized drug-like compounds is a key step in this process. Our group has developed an in-house chemical library called Medicinal and Biological Chemistry (MBC) library. This collection has been successfully used to start several medicinal chemistry programs and developed in an accumulation of more than thirty years of experience in drug design and discovery of new drugs for unmet diseases. It contains over 1,000 compounds, mainly heterocyclic scaffolds...
August 16, 2017: Journal of Chemical Information and Modeling
https://www.readbyqxmd.com/read/28810977/moving-beyond-accidental-leadership-a-graduate-medical-education-leadership-curriculum-needs-assessment
#12
Joshua D Hartzell, Clifton E Yu, Brian M Cohee, Michael R Nelson, Ramey L Wilson
BACKGROUND: Despite calls for greater physician leadership, few medical schools, and graduate medical education programs provide explicit training on the knowledge, skills, and attitudes necessary to be an effective physician leader. Rather, most leaders develop through what has been labeled "accidental leadership." A survey was conducted at Walter Reed to define the current status of leadership development and determine what learners and faculty perceived as key components of a leadership curriculum...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28803611/a-cross-sectional-analysis-of-local-government-health-and-wellbeing-plans-and-priorities-in-victoria-australia
#13
Mark Anthony Alindogan, Eli Ristevski, Anske Robinson
The aim of this study is to explore local health and wellbeing plans and priorities by Victorian local governments (LGs), specifically to: (1) analyse how LG priority areas are described in comparison to the State-level plan; (2) identify differences between regional and metropolitan health priorities; and (3) identify differences between LGs with high and low socioeconomic status. Content analysis of 79 LG health and wellbeing plans was undertaken. Differences in health and wellbeing priorities between LGs were examined using the t-test for two proportions...
August 14, 2017: Australian Journal of Primary Health
https://www.readbyqxmd.com/read/28802449/living-with-an-autonomous-spatiotemporal-home-heating-system-exploration-of-the-user-experiences-ux-through-a-longitudinal-technology-intervention-based-mixed-methods-approach
#14
Martin Kruusimagi, Sarah Sharples, Darren Robinson
Rising energy demands place pressure on domestic energy consumption, but savings can be delivered through home automation and engaging users with their heating and energy behaviours. The aim of this paper is to explore user experiences (UX) of living with an automated heating system regarding experiences of control, understanding of the system, emerging thermal behaviours, and interactions with the system as this area is not sufficiently researched in the existing homes setting through extended deployment. We present a longitudinal deployment of a quasi-autonomous spatiotemporal home heating system in three homes...
November 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28800756/lawsonia-intracellularis-in-the-feces-of-wild-rodents-and-stray-cats-captured-around-equine-farms
#15
Jeong-Min Hwang, Myung-Ji Seo, Jung-Yong Yeh
BACKGROUND: Proliferative enteropathy is a global enteric disease of particular importance in pigs. The causative bacterium, Lawsonia intracellularis, has a wide range of susceptible host species. Recently, L. intracellularis has been recognized as an etiologic agent of an emerging enteric disease in foals called equine proliferative enteropathy (EPE). The presence of L. intracellularis in nonruminant wildlife has raised questions regarding the role of these species in EPE transmission...
August 11, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28789683/voluntary-running-exercise-protects-against-sepsis-induced-early-inflammatory-and-pro-coagulant-responses-in-aged-mice
#16
Karel Tyml, Scott Swarbreck, Cynthia Pape, Dan Secor, James Koropatnick, Qingping Feng, Ruud A W Veldhuizen, Sean E Gill
BACKGROUND: Despite many animal studies and clinical trials, mortality in sepsis remains high. This may be due to the fact that most experimental studies of sepsis employ young animals, whereas the majority of septic patients are elderly (60 - 70 years). The objective of the present study was to examine the sepsis-induced inflammatory and pro-coagulant responses in aged mice. Since running exercise protects against a variety of diseases, we also examined the effect of voluntary running on septic responses in aged mice...
August 8, 2017: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/28789639/cipher-a-flexible-and-extensive-workflow-platform-for-integrative-next-generation-sequencing-data-analysis-and-genomic-regulatory-element-prediction
#17
Carlos Guzman, Iván D'Orso
BACKGROUND: Next-generation sequencing (NGS) approaches are commonly used to identify key regulatory networks that drive transcriptional programs. Although these technologies are frequently used in biological studies, NGS data analysis remains a challenging, time-consuming, and often irreproducible process. Therefore, there is a need for a comprehensive and flexible workflow platform that can accelerate data processing and analysis so more time can be spent on functional studies. RESULTS: We have developed an integrative, stand-alone workflow platform, named CIPHER, for the systematic analysis of several commonly used NGS datasets including ChIP-seq, RNA-seq, MNase-seq, DNase-seq, GRO-seq, and ATAC-seq data...
August 8, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28761786/the-bivalve-thyasira-cf-gouldi-hosts-chemoautotrophic-symbiont-populations-with-strain-level-diversity
#18
Bonita McCuaig, France Liboiron, Suzanne C Dufour
Invertebrates from various marine habitats form nutritional symbioses with chemosynthetic bacteria. In chemosynthetic symbioses, both the mode of symbiont transmission and the site of bacterial housing can affect the composition of the symbiont population. Vertically transmitted symbionts, as well as those hosted intracellularly, are more likely to form clonal populations within their host. Conversely, symbiont populations that are environmentally acquired and extracellular may be more likely to be heterogeneous/mixed within host individuals, as observed in some mytilid bivalves...
2017: PeerJ
https://www.readbyqxmd.com/read/28750223/associations-between-flame-retardant-applications-in-furniture-foam-house-dust-levels-and-residents-serum-levels
#19
Stephanie C Hammel, Kate Hoffman, Amelia M Lorenzo, Albert Chen, Allison L Phillips, Craig M Butt, Julie Ann Sosa, Thomas F Webster, Heather M Stapleton
Polyurethane foam (PUF) in upholstered furniture frequently is treated with flame retardant chemicals (FRs) to reduce its flammability and adhere to rigorous flammability standards. For decades, a commercial mixture of polybrominated diphenyl ethers (PBDEs) called PentaBDE was commonly applied to foam to fulfill these regulations; however, concerns over toxicity, bioaccumulation, and persistence led to a global phase-out in the mid-2000s. Although PentaBDE is still detected in older furniture, other FR compounds such as tris(1,3-dichloroisopropyl) phosphate (TDCIPP) and Firemaster® 550 (FM550) have been increasingly used as replacements...
October 2017: Environment International
https://www.readbyqxmd.com/read/28745638/localization-of-odorant-receptor-genes-in-locust-antennae-by-rna-in-situ-hybridization
#20
Xiao Xu, Yinwei You, Long Zhang
Insects have evolved sophisticated olfactory reception systems to sense exogenous chemical signals. These chemical signals are transduced by Olfactory Receptor Neurons (ORNs) housed in hair-like structures, called chemosensilla, of the antennae. On the ORNs' membranes, Odorant Receptors (ORs) are believed to be involved in odor coding. Thus, being able to identify genes localized to the ORNs is necessary to recognize OR genes, and provides a fundamental basis for further functional in situ studies. The RNA expression levels of specific ORs in insect antennae are very low, and preserving insect tissue for histology is challenging...
July 13, 2017: Journal of Visualized Experiments: JoVE
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