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https://www.readbyqxmd.com/read/29778814/environmental-and-lifestyle-factors-affecting-exposure-to-polycyclic-aromatic-hydrocarbons-in-the-general-population-in-a-middle-eastern-area
#1
Mohammad Hoseini, Ramin Nabizadeh, Juana Maria Delgado-Saborit, Ata Rafiee, Kamyar Yaghmaeian, Saeid Parmy, Sasan Faridi, Mohammad Sadegh Hassanvand, Masud Yunesian, Kazem Naddafi
The aim of this study was to investigate environmental and lifestyle factors affecting exposure to PAHs in the general population in a large city of the Middle East (Tehran) by measuring urinary monohydroxy polycyclic aromatic hydrocarbons (OH-PAHs) and establishing relationships between PAHs exposure and related factors. Urine samples were collected from 222 randomly chosen subjects who were living in the urban area of Tehran, Iran. Subjects were required to complete a detailed questionnaire aimed to document their personal and sociodemographic information, activities, cooking-related appliances, smoking history/exposure, and consumed foodstuff...
May 17, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29770806/a-place-of-many-names-how-three-generations-of-bedouin-women-express-the-meaning-of-home
#2
Nuzha Allassad Alhuzail
This article examines how three generations of Bedouin women in southern Israel express what home means to them through the names they give it: bayt , maskan , and dar . Home has always been significant in the lives of Bedouin women, but Bedouin society is undergoing major changes-culturally, socially, and in the form of settlement. The external form of the Bedouin home has changed, too, from a tent to a stone house, from an open structure to a closed one, from being part of the open space of the desert to being a limited space in a neighborhood...
2018: Journal of housing and the built environment: HBE
https://www.readbyqxmd.com/read/29769698/mutation-screening-using-formalin-fixed-paraffin-embedded-tissues-a-stratified-approach-according-to-dna-quality
#3
Francesco Cucco, Alexandra Clipson, Hannah Kennedy, Joe Sneath Thompson, Ming Wang, Sharon Barrans, Moniek van Hoppe, Eguzkine Ochoa Ruiz, Josh Caddy, Debbie Hamid, Thomas Cummin, Cathy Burton, Andrew J Davies, Peter Johnson, Ming-Qing Du
DNA samples from formalin-fixed paraffin-embedded tissues are highly degraded with variable quality, and this imposes a big challenge for targeted sequencing due to false positives, largely caused by PCR errors and cytosine deamination. To eliminate false positives, a common practice is to validate the detected variants by Sanger sequencing or perform targeted sequencing in duplicate. Technically, PCR errors could be removed by molecular barcoding of template DNA prior to amplification as in the HaloPlexHS design...
May 16, 2018: Laboratory Investigation; a Journal of Technical Methods and Pathology
https://www.readbyqxmd.com/read/29763532/palliative-care-occupies-growing-presence-in-ed
#4
(no author information available yet)
As the benefits of palliative care become more evident in clinical trials, there is growing interest in making such resources available to patients at an earlier stage, such as the ED. However, experts note that emergency staff first must identify available resources and make sure that providers have the primary palliative care skills needed to effectively introduce the topic to appropriate patients and families. Research shows that initiating the call for a palliative care consult while the patient is in the ED can deliver quality-of-life benefits even three months later...
June 2017: ED Management: the Monthly Update on Emergency Department Management
https://www.readbyqxmd.com/read/29759262/focus-on-the-quadruple-aim-development-of-a-resiliency-center-to-promote-faculty-and-staff-wellness-initiatives
#5
Ellen Morrow, Megan Call, Robin Marcus, Amy Locke
DEFINING THE PROBLEM: A growing body of evidence highlights the need for wellness programs to support health care professionals. Although much of the existing literature centers on practicing physicians and physician trainees, there is growing awareness that these challenges are not unique to physicians and affect all members of the health care team. Traumatic and stressful events will always be a part of health care; how these events are addressed on a personal and team level is essential to the success of a health care system...
May 2018: Joint Commission Journal on Quality and Patient Safety
https://www.readbyqxmd.com/read/29755323/environmental-enrichment-prevents-transcriptional-disturbances-induced-by-alpha-synuclein-overexpression
#6
Zinah Wassouf, Thomas Hentrich, Sebastian Samer, Carola Rotermund, Philipp J Kahle, Ingrid Ehrlich, Olaf Riess, Nicolas Casadei, Julia M Schulze-Hentrich
Onset and progression of neurodegenerative disorders, including synucleinopathies such as Parkinson's disease, have been associated with various environmental factors. A highly compelling association from a therapeutic point of view has been found between a physically active lifestyle and a significantly reduced risk for Parkinson's disease. Mimicking such conditions in animal models by promoting physical activity, social interactions, and novel surroundings yields in a so-called enriched environment known to enhance adult neurogenesis, increase synaptic plasticity, and decelerate neuronal loss...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29751825/uneven-malaria-transmission-in-geographically-distinct-districts-of-bobo-dioulasso-burkina-faso
#7
Dieudonné Diloma Soma, Daouda Kassié, Seydou Sanou, Fatou Biribama Karama, Ali Ouari, Wadaka Mamai, Georges Anicet Ouédraogo, Gérard Salem, Roch Kounbobr Dabiré, Florence Fournet
BACKGROUND: Urbanization is a main trend in developing countries and leads to health transition. Although non-communicable diseases are increasing in cities of low-income countries, vector-borne diseases such as malaria, are still present. In the case of malaria, transmission is lower than in rural areas, but is uneven and not well documented. In this study, we wanted to evaluate intra-urban malaria transmission in a West African country (Burkina Faso). METHODS: A cross-sectional study on 847 adults (35 to 59 year-old) and 881 children (6 months to 5 year-old) living in 1045 households of four districts (Dogona, Yeguere, Tounouma and Secteur 25) of Bobo-Dioulasso was performed between October and November 2013...
May 11, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29751532/the-role-of-the-polymeric-immunoglobulin-receptor-and-secretory-immunoglobulins-during-mucosal-infection-and-immunity
#8
REVIEW
Holly Turula, Christiane E Wobus
The gastrointestinal tract houses millions of microbes, and thus has evolved several host defense mechanisms to keep them at bay, and prevent their entry into the host. One such mucosal surface defense is the secretion of secretory immunoglobulins (SIg). Secretion of SIg depends on the polymeric immunoglobulin receptor (pIgR), which transports polymeric Ig (IgA or IgM) from the basolateral surface of the epithelium to the apical side. Upon reaching the luminal side, a portion of pIgR, called secretory component (SC) is cleaved off to release Ig, forming SIg...
May 3, 2018: Viruses
https://www.readbyqxmd.com/read/29730987/stigma-associated-with-medication-treatment-for-young-adults-with-opioid-use-disorder-a-case-series
#9
Scott E Hadland, Tae Woo Park, Sarah M Bagley
BACKGROUND: Opioid-related overdose deaths have risen sharply among young adults. Despite this increase, access to evidence-based medication for opioid agonist treatment (OAT) for youth remains low. Among older adults, barriers to OAT include the paucity of buprenorphine-waivered prescribers and low rates of prescribing among waivered physicians. We have increasingly found in our clinical practice significant stigma related to using OAT to treat addiction for young adults. In this series, we describe three cases of young adults who faced significant stigma related to their treatment...
May 7, 2018: Addiction Science & Clinical Practice
https://www.readbyqxmd.com/read/29728148/an-evidence-based-co-occurring-disorder-intervention-in-va-homeless-programs-outcomes-from-a-hybrid-iii-trial
#10
David A Smelson, Matthew Chinman, Gordon Hannah, Thomas Byrne, Sharon McCarthy
BACKGROUND: Evidence-based treatment for co-occurring disorders is needed within programs that serve homeless Veterans to assist with increasing engagement in care and to prevent future housing loss. A specialized co-occurring disorders treatment engagement intervention called Maintaining Independence and Sobriety Through Systems Integration, Outreach and Networking - Veterans Edition (MISSION-Vet) was implemented within the Housing and Urban Development - Veterans Affairs Supportive Housing (HUD-VASH) Programs with and without an implementation strategy called Getting To Outcomes (GTO)...
May 5, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29726287/disability-concentration-and-access-to-rehabilitation-services-a-pilot-spatial-assessment-applying-geographic-information-system-analysis
#11
Fengsong Gao, Michele Foster, Yan Liu
PURPOSE: Due to geographical disparities, many people with profound or severe disabilities experience considerable delays in rehabilitation treatment, resulting in threats to quality of life. This pilot study aims to identify areas in Greater Brisbane, Australia, with a higher concentration of people with profound or severe disabilities and to evaluate access to rehabilitation services in these areas. METHODS: Data came from the 2016 Australian Census of Population and Housing and the National Health Services Directory...
May 4, 2018: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29725960/towards-portable-large-scale-image-processing-with-high-performance-computing
#12
REVIEW
Yuankai Huo, Justin Blaber, Stephen M Damon, Brian D Boyd, Shunxing Bao, Prasanna Parvathaneni, Camilo Bermudez Noguera, Shikha Chaganti, Vishwesh Nath, Jasmine M Greer, Ilwoo Lyu, William R French, Allen T Newton, Baxter P Rogers, Bennett A Landman
High-throughput, large-scale medical image computing demands tight integration of high-performance computing (HPC) infrastructure for data storage, job distribution, and image processing. The Vanderbilt University Institute for Imaging Science (VUIIS) Center for Computational Imaging (CCI) has constructed a large-scale image storage and processing infrastructure that is composed of (1) a large-scale image database using the eXtensible Neuroimaging Archive Toolkit (XNAT), (2) a content-aware job scheduling platform using the Distributed Automation for XNAT pipeline automation tool (DAX), and (3) a wide variety of encapsulated image processing pipelines called "spiders...
May 3, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29722016/triarabinosylation-is-required-for-nodulation-suppressive-cle-peptides-to-systemically-inhibit-nodulation-in-pisum-sativum
#13
April H Hastwell, Leo Corcilius, James Williams, Peter M Gresshoff, Richard J Payne, Brett J Ferguson
Legumes form root nodules to house beneficial nitrogen-fixing rhizobia bacteria. However, nodulation is resource demanding; hence, legumes evolved a systemic signalling mechanism, called Autoregulation of Nodulation (AON), to control nodule numbers. AON begins with the production of CLE peptides in the root, which are predicted to be glycosylated, transported to the shoot, and perceived. We synthesised variants of nodulation-suppressing CLE peptides to test their activity using petiole feeding to introduce CLE peptides into the shoot...
May 2, 2018: Plant, Cell & Environment
https://www.readbyqxmd.com/read/29716576/protocol-a-multi-level-intervention-program-to-reduce-stress-in-9-1-1-telecommunicators
#14
Hendrika Meischke, Michelle Lilly, Randal Beaton, Rebecca Calhoun, Ann Tu, Scott Stangenes, Ian Painter, Debra Revere, Janet Baseman
BACKGROUND: Nationwide, emergency response systems depend on 9-1-1 telecommunicators to prioritize, triage, and dispatch assistance to those in distress. 9-1-1 call center telecommunicators (TCs) are challenged by acute and chronic workplace stressors: tense interactions with citizen callers in crisis; overtime; shift-work; ever-changing technologies; and negative work culture, including co-worker conflict. This workforce is also subject to routine exposures to secondary traumatization while handling calls involving emergency situations and while making time urgent, high stake decisions over the phone...
May 2, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29714573/a-pilot-experiment-in-responding-to-individual-patient-requests-for-compassionate-use-of-an-unapproved-drug-the-compassionate-use-advisory-committee-compac
#15
Arthur Caplan, Alison Bateman-House, Joanne Waldstreicher, Lisa Fedor, Ramana Sonty, Tito Roccia, Jon Ukropec, Rick Jansson
BACKGROUND: Janssen Research & Development, LLC, part of the Janssen pharmaceutical companies of Johnson & Johnson, and NYU School of Medicine partnered to establish the Compassionate Use Advisory Committee (CompAC) to evaluate the use of an independent, external, expert committee in ensuring transparent, fair, beneficent, evidence-based, and patient-focused compassionate access to investigational medicines, a public health challenge that has been an ongoing issue for over 3 decades...
January 1, 2018: Therapeutic Innovation & Regulatory Science
https://www.readbyqxmd.com/read/29708490/audiology-assistants-results-of-a-multicenter-survey
#16
Roanne Karzon, Lisa Hunter, Wendy Steuerwald
BACKGROUND: Although audiologists have been using support personnel for over 45 yr, controversy and variability continue with respect to the entry-level education, training methods, and scope of practice. PURPOSE: As part of a larger clinical practices survey, this report focuses on use of audiology assistants (AAs) for pediatric settings and "life-span" facilities that had a significant population of pediatric patients. RESEARCH DESIGN: A questionnaire was sent to 116 facilities in geographically diverse locations...
May 2018: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/29705498/whole-exome-sequencing-in-an-italian-family-with-isolated-maxillary-canine-agenesis-and-canine-eruption-anomalies
#17
Ersilia Barbato, Alice Traversa, Rosanna Guarnieri, Agnese Giovannetti, Maria Luce Genovesi, Maria Rosa Magliozzi, Stefano Paolacci, Andrea Ciolfi, Simone Pizzi, Roberto Di Giorgio, Marco Tartaglia, Antonio Pizzuti, Viviana Caputo
OBJECTIVE: The aim of this study was the clinical and molecular characterization of a family segregating a trait consisting of a phenotype specifically involving the maxillary canines, including agenesis, impaction and ectopic eruption, characterized by incomplete penetrance and variable expressivity. DESIGN: Clinical standardized assessment of 14 family members and a whole-exome sequencing (WES) of three affected subjects were performed. WES data analyses (sequence alignment, variant calling, annotation and prioritization) were carried out using an in-house implemented pipeline...
April 21, 2018: Archives of Oral Biology
https://www.readbyqxmd.com/read/29703193/patient-house-calls-in-attica-and-thessaloniki-greece-2005-2015-a-model-for-out-of-hospital-multispecialty-emergency-medicine
#18
George Theocharis, Spyridon G Barbas, Theodore Spiropoulos, Petroula E Stamouli, Dimitrios N Perdikis, Matthew E Falagas
BACKGROUND: The SOS-doctors are a network of physicians who perform house-call visits in the areas of Attica and Thessaloniki, Greece. METHODS: Patients requesting medical services by the SOS doctors during the period 1/1/2005 - 31/12/2015 were eligible for inclusion in this retrospective analysis. RESULTS: During this period 335, 212 home visits were performed. Females used this service more frequently compared to males (60.5% versus 39.5%)...
April 27, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29668804/morphology-of-the-diaphragm-muscle-in-southern-tamandua-tamandua-tetradactyla-and-its-importance-in-cases-of-traumatic-hernia
#19
Érica F S Azevedo, Daniela R Costa E Silva, Tamires V S Natividade, Elane G Giese, Ana Rita DE Lima, Paola C Soares, Érika Branco
The wall of the diaphragm can be affected by changes caused by physical trauma, allowing the passage of viscera between the abdominal cavity and thoracic cavity, thus reducing the space for pulmonary expansion, leading to the formation of hernia and possible death. Thus, we aimed to characterize, size and determine the topography of the diaphragmatic muscle in the Southern Tamandua, since clinical and surgical activities in wild animals have become a reality more and more present in veterinary medicine. We used six adult animals, x-rayed and dissected, followed by collection of fragments of muscular portions for histological analysis...
April 16, 2018: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/29652048/-should-a-doctor-take-into-consideration-the-influence-of-climatic-factors-deliberations-on-the-occasion-of-the-publication-of-a-new-monograph-the-book-of-essays-of-arid-medicine-by-z-r-zununov-i-h-nurov-and-s-z-zununova
#20
E L Povazhnaya
The authors analyze the monograph of the Uzbek scientists professor Z.R. Zununov, I.H. Nurov, and S.Z. Zununova «Essays of arid medicine» (Tashkent: «KAMALAK-PRESS» publishing house, 2016;540). The book presents the results of the comprehensive bioclimatic assessment of the arid zones of Uzbekistan, their extreme climatic conditions (such as high intensity and solar radiation and the considerable duration of its period, dry air and summer heat, sandstorms (the so-called «Afghans»), and the great variety of the natural health-improving factors including mineral waters, microclimate of the speleotherapeutic cave, the desert dune sand, etc...
April 9, 2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
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