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https://www.readbyqxmd.com/read/29345963/deletion-of-estrogen-receptor-alpha-in-skeletal-muscle-results-in-impaired-contractility-in-female-mice
#1
Brittany C Collins, Tara L Mader, Christine A Cabelka, Melissa R Iñigo, Espen E Spangenburg, Dawn A Lowe
Estradiol deficiency in females can result in skeletal muscle strength loss, and treatment with estradiol mitigates the loss. There are three primary estrogen receptors and estradiol elicits effects through these receptors in various tissues. Ubiquitous estrogen receptor α (ERα) knockout mice exhibit numerous biological disorders, but little is known regarding the specific role of ERα in skeletal muscle contractile function. The purpose of this study was to determine the impact of skeletal muscle specific ERα deletion on contractile function, hypothesizing that ERα is a main receptor through which estradiol affects muscle strength in females...
January 18, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29279564/a-case-of-a-giant-cell-tumor-of-the-tendon-sheath-of-the-middle-phalanx-of-the-fourth-toe
#2
Kyochika Okabe, Toshihiko Hoashi, Mariko Asahara, Eiko Esaki, Michiko Ito, Rui Otsuka, Yoko Funasaka, Hidehisa Saeki
Giant cell tumors of the tendon sheath (GCT-TS) are one of the most common tumors of the hand, along with ganglions. However, occurrence in the toes is far less common. Here we present a rare case of GCT-TS at the middle phalanx level of the flexor digitorum longus tendon sheath. Magnetic resonance imaging showed low intensity both on T1 and T2 weighted images. To the best of our knowledge, our case is the first report of a GCT-TS arising at the middle phalanx level of the flexor digitorum longus tendon sheath of the fourth toe...
2017: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/29275614/-wound-repair-and-functional-reconstruction-of-high-voltage-electrical-burns-in-wrists
#3
Y M Shen, C X Ma, F J Qin, C Zhang, C Wang, X H Hu
Objective: To explore the methods and effects of wound repair and functional reconstruction of high-voltage electrical burns in wrists. Methods: From January 2009 to June 2016, 71 patients with high-voltage electrical burns in wrists were hospitalized, with 118 wrist wounds including 21 of type Ⅰ, 69 of type Ⅱ, 9 of type Ⅲ, and 19 of type Ⅳ. According to the wrist injuries, different surgical operations were performed. Forearm amputation was conducted in 20 wrists with necrosis in the distal end. On the basis of fasciotomy for decompression, early debridement was performed on the other 98 wrist wounds...
December 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/29248396/biomechanical-study-comparing-pulvertaft-suture-to-step-cut-suture
#4
A Duprat, L-E Gayet, C Breque, M Freslon
Tendon grafts are a component of the therapeutic arsenal for managing chronic flexor tendons injuries in the hand, especially during two-stage Hunter reconstruction. The purpose of this anatomical study was to compare the strength of the Pulvertaft weave versus the step-cut suture used for flexor tendon reconstruction to determine their role in early active mobilization. We performed a biomechanical study with cadaver specimens. Thirty-four hands were randomized and the tendons from both hands were equally assigned to each group...
December 13, 2017: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/29239782/the-morphology-of-foot-soft-tissues-is-associated-with-running-shoe-type-in-healthy-recreational-runners
#5
Xianyi Zhang, Tijs Delabastita, Joselien Lissens, Floor De Beenhouwer, Benedicte Vanwanseele
OBJECTIVES: To determine the differences in the morphology of foot soft tissues between runners using different types of running shoes. DESIGN: Cross-sectional study. METHODS: Thirty-eight recreational runners were divided into four groups based on running shoe type, namely, neutral shoes, motion control shoes, minimalistic shoes and neutral shoes with custom-made insoles. An arch height index and a relative arch deformation index were calculated for each participant...
November 22, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29238405/the-effect-of-a-running-task-on-muscle-shear-elastic-modulus-of-posterior-lower-leg
#6
Shuhei Ohya, Masatoshi Nakamura, Takafumi Aoki, Daichi Suzuki, Takanori Kikumoto, Emi Nakamura, Wataru Ito, Ryo Hirabayashi, Tomoya Takabayashi, Mutsuaki Edama
Background: Medial tibial stress syndrome (MTSS) is one of the most common causes of exercise-related leg pain in runners. Because stopping training due to pain from MTSS could decrease the athlete's competitiveness, it is necessary to construct MTSS prevention and treatment programs. However, the effect of running, which is believed to cause MTSS, on shear elastic modulus of the posterior lower leg is unclear. Therefore, the purpose of this study was to investigate the effect of 30 min of running on shear elastic modulus of the posterior lower leg in healthy subjects...
2017: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29218383/linburg-comstock-variation-and-syndrome-a-meta-analysis
#7
REVIEW
Kaissar Yammine, Mirela Erić
INTRODUCTION: Linburg-Comstock variation often connecting the flexor pollicis longus and flexor digitorum profundus of the index finger at a different level with significant discrepancy between clinical and cadaveric frequencies reported in the literature. Although this variation is quite prevalent, it is yet frequently unrecognized. The aim of this meta-analysis is to generate more accurate weighted frequency values of the Linburg-Comstock variation and to look for possible association with ethnicity, laterality, gender and side...
December 7, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29166622/morphological-characteristics-and-variations-of-the-human-quadratus-plantae-muscle
#8
Bettina Pretterklieber
The quadratus plantae (QP) is a highly variable structure. A number of partly inexact descriptions of this entity have been provided in textbooks of anatomy. Although several authors have examined the QP, its exact site of origin and type of insertion have hitherto not been specified. The aim of this study has been to provide detailed qualitative and quantitative data about the number of heads, points of origin, and type of insertion of the QP. The QP in both feet of 50 formalin-fixed specimens of body donors (25 men and women) were analyzed by gross anatomical dissection...
November 19, 2017: Annals of Anatomy, Anatomischer Anzeiger: Official Organ of the Anatomische Gesellschaft
https://www.readbyqxmd.com/read/29166314/step-cut-lengthening-a-technique-for-treatment-of-flexor-pollicis-longus-tendon-rupture
#9
Chew-Wei Chong, Shih-Heng Chen
Reconstruction of a tendon defect is a challenging task in hand surgery. Delayed repair of a ruptured flexor pollicis longus (FPL) tendon is often associated with tendon defect. Primary repair of the tendon is often not possible, particularly after debridement of the unhealthy segment of the tendon. As such, various surgical treatments have been described in the literature, including single-stage tendon grafting, 2-stage tendon grafting, flexor digitorum superficialis tendon transfer from ring finger, and interphalangeal joint arthrodesis...
November 21, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29148083/macroscopic-and-microscopic-analyses-in-flexor-tendons-of-the-tarsometatarso-phalangeal-joint-of-ostrich-struthio-camelus-foot-with-energy-storage-and-shock-absorption
#10
Rui Zhang, Dianlei Han, Gang Luo, Lei Ling, Guoyu Li, Qiaoli Ji, Jianqiao Li
Flexor tendons function as energy storage and shock absorption structures in the tarsometatarso-phalangeal joint (TMTPJ) of ostrich feet during high-speed and heavy-load locomotion. In this study, mechanisms underlying the energy storage and shock absorption of three flexor tendons of the third toe were studied using histology and scanning electron microscopy (SEM). Macroscopic and microscopic structures of the flexor tendons in different positions of TMTPJ were analyzed. Histological slices showed collagen fiber bundles of all flexor tendons in the middle TMTPJ were arranged in a linear-type, but in the proximal and distal TMTPJ, a wavy-type arrangement was found in the tendon of the M...
November 17, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29117832/prevalence-of-absence-of-palmaris-longus-and-its-association-with-gender-hand-dominance-and-absence-of-fds-tendon-to-little-finger-among-malay-population
#11
Mei Wen Yong, Nabihah Yusof, Lekhraj Rampal, Manohar Arumugam
BACKGROUND: Palmaris Longus is being widely used in reconstructive, plastic and cosmetic surgeries due to its long tendon. It is the most readily available source for tendon grafting. The objective of this study was to determine the prevalence of absence of Palmaris Longus and its association with gender, hand dominance and absence of FDS (flexor digitorum superficialis) tendon to little finger among Malay population. METHODS: An analytical cross sectional study design was used and a self-administered proforma was distributed for data collection...
December 2017: Journal of Hand Surgery Asian-Pacific Volume
https://www.readbyqxmd.com/read/29111461/sonographic-identification-of-the-flexor-digitorum-accessorius-longus-tendon
#12
Jeffrey R LaVallee, Adam M Pourcho, P Troy Henning, H Wayne Lambert
No abstract text is available yet for this article.
October 27, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29102441/incobotulinum-toxin-a-in-parkinson-s-disease-with-foot-dystonia-a%C3%A2-double-blind-randomized-trial
#13
Isabelle Rieu, Bertrand Degos, Giovanni Castelnovo, Christophe Vial, Elodie Durand, Bruno Pereira, Marion Simonetta-Moreau, Sophie Sangla, Frédérique Fluchère, Dominique Guehl, Pierre Burbaud, Christian Geny, Dominique Gayraud, Fabienne Ory-Magne, Françoise Bouhour, Elisabeth Llinares, Philippe Derost, Ana Marques, Franck Durif
INTRODUCTION: Plantar flexion of toe dystonia is very painful and leads to difficulties in walking. The objective of this study was to investigate the effect of incobotulinum toxin A (Xeomin) in the treatment of this type of dystonia in parkinsonian patients, using a randomized, double blind, placebo-controlled trial. METHODS: 45 parkinsonian patients with painful dystonic plantar flexion of toes were injected either with incobotulinum toxin A (Btx group), or with placebo in two muscle targets: the Flexor digitorum longus and the Flexor digitorum brevis...
October 19, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29095192/interposition-tendon-graft-and-tension-in-the-repair-of-closed-rupture-of-the-flexor-digitorum-profundus-in-zone-iii-or-iv
#14
Young Jun Kim, Jong Hun Baek, Jin Sung Park, Jae Hoon Lee
We report the results of interposition tendon grafts using the ipsilateral palmaris longus tendon in 12 patients with closed flexor digitorum profundus tendon ruptures in zone III or IV of 14 digits between June 2006 and October 2015. Before surgery, 2 patients were diagnosed with closed tendon ruptures that occurred after nonunion of hamate hook fractures. The other 10 patients were diagnosed with spontaneous tendon ruptures of unknown cause. In 2 of the 10 patients with spontaneous tendon rupture, the cause of the rupture was not found...
October 31, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29079740/anatomical-study-of-the-neurovascular-in-flexor-hallucis-longus-tendon-transfers
#15
Haijiao Mao, Wenwei Dong, Zengyuan Shi, Weigang Yin, Dachuan Xu, Keith L Wapner
The transfer of the flexor hallucis longus tendon or flexor digitorum longus tendon is frequently used for the treatment of posterior tibial tendon insufficiency or chronic Achilles tendinopathy. According to several anatomical studies, harvesting the flexor hallucis longus (FHL) tendon may cause nerve injury. Sixty-eight embalmed feet were dissected and anatomically classified to define the relationship between Henry's knot and the plantar nerves. Two different configurations were identified. In Pattern 1, which was observed in 64 specimens (94...
October 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29034479/scaling-of-the-ankle-extensor-muscle-tendon-units-and-the-biomechanical-implications-for-bipedal-hopping-locomotion-in-the-post-pouch-kangaroo-macropus-fuliginosus
#16
Edward P Snelling, Andrew A Biewener, Qiaohui Hu, David A Taggart, Andrea Fuller, Duncan Mitchell, Shane K Maloney, Roger S Seymour
Bipedal hopping is used by macropods, including rat-kangaroos, wallabies and kangaroos (superfamily Macropodoidea). Interspecific scaling of the ankle extensor muscle-tendon units in the lower hindlimbs of these hopping bipeds shows that peak tendon stress increases disproportionately with body size. Consequently, large kangaroos store and recover more strain energy in their tendons, making hopping more efficient, but their tendons are at greater risk of rupture. This is the first intraspecific scaling analysis on the functional morphology of the ankle extensor muscle-tendon units (gastrocnemius, plantaris and flexor digitorum longus) in one of the largest extant species of hopping mammal, the western grey kangaroo Macropus fuliginosus (5...
December 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28986075/the-scope-of-upper-limb-surgery-for-tetraplegics-role-of-tendon-transfers-and-universal-cuff
#17
Mukul Mohindra, Paritosh Gogna, Sukhbir Singh Sangwan, Sahil Gaba, Zile Singh Kundu
OBJECTIVE: The aim of this study was to evaluate the role of tendon transfers and universal cuff in restoring hand function in tetraplegic patients. METHODS: Twenty-one upper limbs on 12 tetraplegic patients (9 males and 3 females); mean age: 42.2 years (range 22-58 years) with a spinal cord injury at or distal to C6, were included in this study. Key pinch was restored using Brachioradialis to Flexor Pollicis Longus transfer and hook using Pronator Teres to Flexor Digitorum Profundus transfer...
October 4, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28972426/an-investigation-of-a-novel-tendon-transfer-surgery-for-high-median-ulnar-nerve-palsy-in-a-chicken-model
#18
Geoffrey R Browning, Anthony H Le, Jennifer J Warnock, Ravi Balasubramanian
PURPOSE: The state-of-the-art tendon transfer surgery for high median-ulnar nerve palsy involves directly suturing four finger flexor tendons to one wrist extensor muscle. This couples finger flexion limiting the patient's ability to grasp objects. Therefore, we propose a new approach to attach a novel passive implant to the extensor digitorum longus tendon in order to create a differential mechanism in situ. The implant is expected to enable the fingers to adapt to an object's shape during grasping...
October 3, 2017: Journal of Investigative Surgery: the Official Journal of the Academy of Surgical Research
https://www.readbyqxmd.com/read/28963128/hind-limb-motoneurons-activity-during-fictive-locomotion-or-scratching-induced-by-pinna-stimulation-serotonin-or-glutamic-acid-in-brain-cortex-ablated-cats
#19
Sergio H Duenas-Jimenez, Luis Castillo Hernandez, Braniff de la Torre Valdovinos, Gerardo Mendizabal Ruiz, Judith M Duenas Jimenez, Viviana Ramirez Abundis, Irene Guadalupe Aguilar Garcia
In brain cortex-ablated cats (BCAC), hind limb motoneurons activity patterns were studied during fictive locomotion (FL) or fictive scratching (FS) induced by pinna stimulation. In order to study motoneurons excitability: heteronymous monosynaptic reflex (HeMR), intracellular recording, and individual Ia afferent fiber antidromic activity (AA) were analyzed. The intraspinal cord microinjections of serotonin or glutamic acid effects were made to study their influence in FL or FS During FS, HeMR amplitude in extensor and bifunctional motoneurons increased prior to or during the respective electroneurogram (ENG)...
September 2017: Physiological Reports
https://www.readbyqxmd.com/read/28950148/the-influence-of-foot-position-on-lower-leg-muscle-activity-during-a-heel-raise-exercise-measured-with-fine-wire-and-surface-emg
#20
Hiroshi Akuzawa, Atsushi Imai, Satoshi Iizuka, Naoto Matsunaga, Koji Kaneoka
OBJECTIVE: Exercises for lower leg muscles are important to improve function. To examine the influence of foot position on lower leg muscle activity during heel raises. DESIGN: Cross-sectional laboratory study. SETTING: Laboratory. PARTICIPANTS: Fourteen healthy men participated in this study. MAIN OUTCOME MEASURES: The muscle activity levels of the tibialis posterior (TP), peroneus longus (PL), flexor digitorum longus (FDL) and medial gastrocnemius (MG) were measured...
November 2017: Physical Therapy in Sport
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