Jinhuan Yue, Sheng-Wang Han, Xiao Liu, Song Wang, Wei-Wei Zhao, Li-Na Cai, Dan-Na Cao, Jeffrey Zhongxue Mah, Yu Hou, Xuan Cui, Yang Wang, Li Chen, Ang Li, Xiao-Ling Li, Guanhu Yang, Qinhong Zhang
BACKGROUND: Amnestic mild cognitive impairment (aMCI) is an early stage of Alzheimer's disease (AD). Regional homogeneity (ReHo) and amplitude of low-frequency fluctuation (ALFF) are employed to explore spontaneous brain function in patients with aMCI. This study applied ALFF and ReHo indicators to analyze the neural mechanism of aMCI by resting-state functional magnetic resonance imaging (rs-fMRI). METHODS: Twenty-six patients with aMCI were included and assigned to the aMCI group...
2023: Frontiers in Neurology