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mehrdad mohammadpour

Mehrdad Mohammadpour, Mojtaba Abrishami, Ahmad Masoumi, Hassan Hashemi
PURPOSE: To review the background, epidemiology and current management of trachoma in endemic areas and worldwide. METHODS: Review of literature. RESULTS: Trachoma is one of the leading causes of preventable blindness in developing countries. It was reported as one of the seven most neglected tropical diseases that can be prevented via drug administration. Its infliction is primarily aimed at those living in areas deprived of clean water and proper sanitation...
December 2016: Journal of Current Ophthalmology
Mehrdad Mohammadpour, Kazem Mohammad, Nasser Karimi
PURPOSE: To evaluate the agreement among Pentacam, Orbscan and ultrasound (US) pachymetry for measurement of central corneal thickness (CCT) in thin corneas with normal topographic pattern. METHODS: We included 88 eyes of 44 refractive surgery candidates with thinnest pachymetric readings of 500 micrometers (μm) or less on Orbscan, a normal topographic pattern, no sign of keratoconus, and best corrected visual acuity (BCVA) of 20/20. Pentacam, Orbscan and US were performed in one session by the same examiner...
July 2016: Journal of Ophthalmic & Vision Research
Mehrdad Mohammadpour, Zahra Heidari, Hossein Mohammad-Rabei, Ebrahim Jafarzadehpur, Mahmoud Jabbarvand, Hassan Hashemi, Mehdi Khabazkhoob
PURPOSE: To evaluate the correlation between refractive, corneal, and residual astigmatism and higher order aberrations (HOA) in refractive surgery candidates. METHODS: Three hundred and seventy-five eyes of 188 patients aged 28.2 ± 6.24 years with a predominance of females (62.7%) were enrolled in this study. Refraction, topography (Orbscan IIz, Bausch & Lomb, Rochester, NY, USA), and aberrometry (Zywave, Bausch & Lomb, Rochester, NY, USA) were performed to determine refractive and corneal astigmatism and HOA for all participants...
September 2016: Journal of Current Ophthalmology
Mehrdad Mohammadpour, Hassan Hashemi, Mahmoud Jabbarvand, Kamran Rahmatnejad, Fatemeh Alsadat Sabet
PURPOSE: To evaluate the efficacy of photorefractive keratectomy (PRK) using the advanced personalized treatment (APT) nomogram for correction of moderate to high astigmatism. METHODS: This prospective interventional case series included 60 consecutive eyes of 30 patients undergoing wavefront-guided PRK (Zyoptix 217 Z100 excimer laser, Bausch & Lomb, Munich, Germany) using the APT nomogram and iris registration for myopic astigmatism. Mitomycin-C was applied intraoperatively in all eyes...
April 2016: Journal of Ophthalmic & Vision Research
Mehrdad Mohammadpour, Siamak Maleki, Hassan Hashemi, Amir Houshang Beheshtnejad
PURPOSE: To describe a case of chronic graft versus host disease (GVHD) leading to severe dry eye and recurrent corneal perforation in both eyes, its stepwise management and histopathological reports. CASE REPORT: A 22-year-old woman with a history of thalassemia and subsequent high-dose chemotherapy followed by allogeneic bone marrow transplant (BMT) was referred to Farabi Eye Hospital. Despite aggressive medical and surgical intervention, corneal vascularization in her right eye progressed and led to corneal perforation...
January 2016: Journal of Ophthalmic & Vision Research
Mehrdad Mohammadpour, Fatemeh Alsadat Sabet
PURPOSE: To report the anatomical and visual outcomes of double layered amniotic membrane transplantation (AMT) in eyes with advanced Pseudomonas keratitis leading to Descemetocele formation. METHODS: This prospective interventional case series included 6 eyes of 6 female patients with pseudomonas keratitis caused by contact lens-induced infection who underwent double layered AMT. Surgery was performed after the ulcers were found to be poorly responsive to antibiotics, and severe thinning or Descemetocele had developed...
January 2016: Journal of Ophthalmic & Vision Research
Zhaleh Rajavi, Mohammad Ali Javadi, Narsis Daftarian, Sare Safi, Farhad Nejat, Armin Shirvani, Hamid Ahmadieh, Saeid Shahraz, Hossein Ziaei, Hamidreza Moein, Behzad Fallahi Motlagh, Sepehr Feizi, Alireza Foroutan, Hassan Hashemi, Seyed Javad Hashemian, Mahmoud Jabbarvand, Mohammad Reza Jafarinasab, Farid Karimian, Hossein Mohammad-Rabei, Mehrdad Mohammadpour, Nader Nassiri, Mahmoodreza Panahi-Bazaz, Mohammad Reza Rohani, Mohammad Reza Sedaghat, Kourosh Sheibani
PURPOSE: To customize clinical practice guidelines (CPGs) for cataract management in the Iranian population. METHODS: First, four CPGs (American Academy of Ophthalmology 2006 and 2011, Royal College of Ophthalmologists 2010, and Canadian Ophthalmological Society 2008) were selected from a number of available CPGs in the literature for cataract management. All recommendations of these guidelines, together with their references, were studied. Each recommendation was summarized in 4 tables...
October 2015: Journal of Ophthalmic & Vision Research
Mehrdad Mohammadpour, Ifa Etesami, Zahra Yavari, Mohammad Naderan, Fatemeh Abdollahinia, Mahmoud Jabbarvand
BACKGROUND: To evaluate and compare corneal biomechanical indices and their specificity among keratoconus (KC), keratoconus suspect (KCS), and normal eyes (NL) before and after controlling potential confounders. MATERIALS AND METHODS: A total of 160 eyes in three groups were included prospectively: NL, KC, and KCS groups based on clinical examination and topography. Corneal hysteresis (CH) and corneal resistance factor (CRF) were measured by the ocular response analyzer...
May 2015: Oman Journal of Ophthalmology
Mehrdad Mohammadpour, Hassan Hahemi, Mahmoud Jabbarvand
PURPOSE: To describe a novel surgical technique for the management of progressive keratoconus by simultaneous femtosecond laser-assisted Myoring implantation and accelerated corneal intrastromal collagen cross-linking with Dextran Free Riboflavin. METHODS: After creating a corneal pocket with femtosecond laser, Dextran Free Riboflavin was injected into the intrastromal pocket. Then the Myoring was implanted in the corneal pocket and accelerated corneal intrastromal collagen cross-linking was performed with no epithelial debridement...
February 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Mehrdad Mohammadpour, Mahmoud Jabbarvand, Hassan Hashemi, Elham Delrish
BACKGROUND: Angiogenesis-related corneal blindness includes the spectrum of corneal diseases that are caused by pathological angiogenesis, leading to untoward visual impairment. The purpose of this study was to investigate the antineovascularization effect of topical silica nanoparticles (SiNPs) in inhibiting chemical-burn-induced corneal neovascularization. MATERIALS AND METHODS: A total number of 20 corneas of 10 Wistar Albino rats were included in this study...
2015: Advanced Biomedical Research
Mehrdad Mohammadpour, Zahra Heidari, Mehdi Khabazkhoob, Afsaneh Amouzegar, Hassan Hashemi
PURPOSE: To investigate the correlation of major components of ocular astigmatism in myopic patients in an academic hospital. METHODS: This cross-sectional study was conducted on 376 eyes of 188 patients who were referred to Farabi Eye Hospital for refractive surgery. Preoperative examinations including refraction and corneal topography were performed for all candidates to measure refractive and corneal astigmatism. Ocular residual astigmatism was calculated using vector analysis...
February 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Mehrdad Mohammadpour, Alireza Lashay, Ghasem Saeedi Anari, Fatemeh Abdi, Abbas Kermanshahani
A 23-year-old girl presented with blurred vision in her left eye since 2 months ago. Her past medical history was unremarkable. On presentation, her left best corrected visual acuity was 20/80. Anterior segment exam was unremarkable. Posterior segment exam showed an ill-defined green gray elevation in the fovea with surrounding subretinal fluid. The right eye exam was normal. Fluorescein Angiography and Optic Coherence Tomography of the left eye was compatible with Choroidal Neovascularization (CNV).
July 2015: Archives of Iranian Medicine
Maryam Amirchaghmaghi, Zahra Delavarian, Mehrdad Iranshahi, Mohammad Taghi Shakeri, Pegah Mosannen Mozafari, Amir Hushang Mohammadpour, Fatemeh Farazi, Milad Iranshahy
Background and aims. Standard treatment of oral lichen planus (OLP) includes topical or systemic corticosteroids that have many adverse effects. A trend toward alternative natural or herbal drugs has attended recently. This study was conducted to evaluate the effect of quercetin in treatment of erosive-atrophic OLP. Materials and methods. Thirty patients participated in this randomized clinical trial from April 2010 to June 2010 (TRIAL REGISTRATION NUMBER: NCT01375101). Patients were randomly allocated in two groups...
2015: Journal of Dental Research, Dental Clinics, Dental Prospects
Mehrdad Mohammadpour, Afsaneh Amouzegar, Hassan Hashemi, Mahmoud Jabbarvand, Hamed Kordbacheh, Firoozeh Rahimi, Mohammad Naser Hashemian
PURPOSE: To assess the effect of two silicone hydrogel contact lenses with high oxygen permeability in patients having photorefractive keratectomy (PRK). SETTING: Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran. METHODS: Sixty patients (120 eyes) who had bilateral PRK were enrolled in this double blind clinical trial. Each patient was fitted with a Lotrafilcon B (Air Optix(®)AQUA, Ciba Vision, Duluth, GA, USA) lens in one eye and a Balafilcon A (PureVision™ Bausch & Lomb, Rochester, NY, USA) lens in the fellow eye...
June 2015: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
Mahgol Farjadnia, Mohammad Naderan, Mehrdad Mohammadpour
Keratoconus (KC) is the most common ectasia of the cornea and is a common reason for corneal transplant. Therapeutic strategies that can arrest the progression of this disease and modify the underlying pathogenesis are getting more and more popularity among scientists. Cumulating data represent strong evidence of a genetic role in the pathogenesis of KC. Different loci have been identified, and certain mutations have also been mapped for this disease. Moreover, Biophysical properties of the cornea create an appropriate candidate of this tissue for gene therapy...
January 2015: Oman Journal of Ophthalmology
Mohammad Nasser Hashemian, Mohammad Ali Zare, Mehrdad Mohammadpour, Firouzeh Rahimi, Mohammad Reza Fallah, Fereydoun Keramat Panah
PURPOSE: To compare the visual, refractive, and keratometric outcomes of single-segment conventional and severe keratoconus (SK) types of Intacs for correction of inferior keratoconus (KCN). METHODS: A total number of 41 consecutive eyes of 23 patients with a diagnosis of inferior KCN underwent Intacs implantation. Eight eyes were excluded due to postoperative complications (4 eyes) and loss to follow-up (4 eyes) and finally 33 eyes underwent statistical analysis...
July 2014: Journal of Ophthalmic & Vision Research
Hassan Hashemi, Mohammad A Seyedian, Mehrdad Mohammadpour
PURPOSE OF REVIEW: Presence of a small pupil is still considered a major challenge for cataract surgeons. Appropriate mydriasis and maintaining it is of paramount importance to prevent potential serious complications. Recently, more interventions and instruments are available for the cataract surgeons to deal with these challenging cases. The intention of this review is to discuss the preoperative and intraoperative considerations and techniques for cataract surgery in small pupil and related conditions and to discuss new developments in management of small pupil in femtosecond laser-assisted cataract surgery...
January 2015: Current Opinion in Ophthalmology
Mehrdad Mohammadpour, Hassan Hashemi, Mahmoud Jabbarvand, Elham Delrish
PURPOSE: The aim of this study was to investigate transmission of topical silicate nanoparticles (SiNPs) through the corneal stroma, anterior chamber, and vitreous fluids by scanning electron microscopy (SEM), transmission electron microscopy (TEM), and inductively coupled plasma atomic emission spectrometry (ICP-AES), respectively. METHODS: SiNPs with a mean diameter of 40.6 ± 5.6 nm determined by dynamic light scattering were used in this study. The permeability of SiNPs was examined across isolated corneal buttons over a 30-minute period...
July 2014: Cornea
Mehrdad Mohammadpour, Mahmood Jabbarvand, Nasser Karimi
As the number of contact-lens wearers rises worldwide, Pseudomonas aeruginosa (PA) keratitis is attracting more attention as a major public health issue. Corneal lesions of PA, being the most intimidating complication of contact-lens wearer, can progress rapidly in spite of local antibiotic treatment, and may result in perforation and the permanent loss of vision. One of the explanations proposed for the evasion of the pathogen from immune responses of the host as well as antibacterial treatment is the fact that invasive clinical isolates of PA have the unusual ability to invade and replicate within surface corneal epithelial cells...
2012: Medical Hypothesis, Discovery and Innovation in Ophthalmology
Mahmoud Jabbarvand, Hassan Hashemi, Mehrdad Mohammadpour, Hassan Khojasteh, Mehdi Khodaparast, Hesam Hashemian
PURPOSE: The aim of this study was to evaluate the clinical outcomes of intrastromal MyoRing (Dioptex, GmbH, Linz, Austria) implantation at 2 different depths of 250 and 300 μm. METHODS: This was a prospective interventional randomized controlled trial, a pilot study. Keratoconic patients with keratometry values between 48 and 52 diopters were randomly divided into 2 groups. A continuous intrastromal corneal ring of the same size was implanted at 2 different stromal depths of 250 μm (group 1) and 300 μm (group 2) using femtosecond laser technology for both groups...
February 2014: Cornea
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