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extraskeletal osteosarcoma

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https://www.readbyqxmd.com/read/28434377/a-primary-extraskeletal-osteosarcoma-of-the-mesentery-a-case-report
#1
Nathalie E J van den Broek, Paul Willemsen, Caroline Mattelaer
Extraskeletal osteosarcoma is a rare and invasive malignancy, typically located in the soft tissue without attachment to the skeleton. The present study reports a case of a primary mesenteric extraskeletal osteosarcoma of a 71-year-old woman. The patient complained of an incomplete defecation. Colonoscopy showed an ulcer with impression of external compression of the sigmoid. An additional abdominal computed tomography (CT) scan revealed a large, almost completely calcified, mass in the left lower abdomen causing hydronephrosis of the left kidney...
April 24, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28384952/a-case-report-on-extraskeletal-osteosarcoma
#2
Vivek Verma, Ashish Gulia, Ajay Puri
No abstract text is available yet for this article.
February 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28335813/tumor-lysis-syndrome-in-an-extraskeletal-osteosarcoma-a-case-report-and-review-of-the-literature
#3
Vito Emanuele Catania, Michele Vecchio, Michele Malaguarnera, Roberto Madeddu, Giulia Malaguarnera, Saverio Latteri
BACKGROUND: This case report describes a spontaneous tumor lysis syndrome due to a rare solid tumor. CASE PRESENTATION: A 65-year-old white woman had tumor lysis syndrome, which represent a dangerous oncological emergency. This syndrome occurs usually with a hematological tumor, but in this case our patient had a solid tumor, which was a rare extraskeletal osteosarcoma, localized in her pelvic region. She also had lung metastases and bilateral hydronephrosis. After spontaneous tumor lysis syndrome, she had acute renal insufficiency, which was treated with hemodialysis and successively with rasburicase, Kayexalate (sodium polystyrene sulfonate), and febuxostat...
March 24, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28289512/giant-abdominal-osteosarcoma-causing-intestinal-obstruction-treated-with-resection-and-adjuvant-chemotherapy
#4
Alexandros Diamantis, Grigorios Christodoulidis, Dionysia Vasdeki, Foteini Karasavvidou, Evangelos Margonis, Konstantinos Tepetes
Extraskeletal osteosarcoma (ESOS) is an uncommon tumor that accounts for 1% of all soft tissue sarcomas and 4% of all osteosarcomas. Its presentation may be atypical, while pain has been described as the most common symptom. Radiological findings include a large mass in the soft-tissues with massive calcifications, but no attachment to the adjacent bone or periosteum. We present the case of a 73-year-old gentle man who presented with a palpable, tender abdominal mass and symptoms of bowel obstruction. Computer tomography images revealed a large space-occupying heterogeneous, hyper dense soft tissue mass involving the small intestine...
February 27, 2017: World Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28235629/primary-extraskeletal-osteosarcoma-a-clinicopathological-study-of-18-cases-focusing-on-mdm2-amplification-status
#5
Kyoko Yamashita, Kenichi Kohashi, Yuichi Yamada, Yoshihiro Nishida, Hiroshi Urakawa, Yoshinao Oda, Shinya Toyokuni
Extraskeletal osteosarcoma (ESOS) is an uncommon malignant neoplasm. Most ESOSs are high grade, although some low-grade cases have been reported. A few cases of ESOS with MDM2 amplification have also been reported, suggesting some similarity to skeletal low-grade osteosarcoma such as parosteal osteosarcoma, where MDM2 is often amplified. However, the frequency of low-grade cases and cases with MDM2 amplification among ESOSs remains unknown and their relationship is unclear. To clarify this, we examined 18 primary ESOS cases clinically, pathologically, and genetically, focusing on their MDM2 amplification status...
February 21, 2017: Human Pathology
https://www.readbyqxmd.com/read/28173679/-primary-extraskeletal-osteosarcoma-of-thoracic-cavity-with-lung-metastasis-report-of-a-case
#6
H Jiang, L H Zheng, J H Yang, X W Xu, J Li
No abstract text is available yet for this article.
February 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28167373/extraskeletal-osteosarcoma-a-european-musculoskeletal-oncology-society-study-on-266-patients
#7
A Longhi, S S Bielack, R Grimer, J Whelan, R Windhager, A Leithner, A Gronchi, D Biau, P Jutte, A H Krieg, F M Klenke, G Grignani, D M Donati, R Capanna, J Casanova, C Gerrand, G Bisogno, S Hecker-Nolting, M De Lisa, L D'Ambrosio, M Willegger, G Scoccianti, S Ferrari
PURPOSE: Prognosis of extraskeletal osteosarcoma (ESOS) is reported to be poorer than that of skeletal osteosarcoma. This multicenter retrospective study aimed to evaluate factors influencing ESOS prognosis. PATIENTS AND METHODS: Members of the European Musculoskeletal Oncology Society (EMSOS) submitted institutional data on patients with ESOS. RESULTS: Data from 274 patients treated from 1981 to 2014 were collected from 16 EMSOS centres; 266 patients were eligible...
February 3, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28105506/cutaneous-osteosarcoma-arising-from-a-burn-scar
#8
Min A Lee, Jaehyuck Yi, Jong Min Chae
Tumors that develop in old burn scars are usually squamous cell carcinomas. Sarcomas have also been reported, albeit rarely. To our knowledge, there has been only one case report of an extraskeletal osteosarcoma arising in a prior burn scar reported in the English-language literature, mainly discussing the clinicopathological features. Herein, we present a case of cutaneous osteosarcoma visualized as a mineralized soft-tissue mass arising from the scar associated with a previous skin burn over the back. This seems to be the first report describing the imaging features of a cutaneous osteosarcoma from an old burn scar...
January 19, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/27853024/extraskeletal-osteosarcoma-of-the-orbit-a-clinicopathologic-case-report-and-review-of-literature
#9
V M D S de Maeyer, P A F A Kestelyn, Akash D Shah, C M Van Den Broecke, H G N Denys, C E Decock
Primary extraskeletal osteosarcoma (EOS) is an extremely rare malignancy. In this report, the clinical course of a 32-year-old man presenting with proptoses is described. Medical history included Hirschsprung disease (HD), horseshoe kidney, azoospermia, and vertebral anomalies. Imaging of the orbit showed an oval, well-defined heterogeneous mass adjacent to the lateral wall of the orbit. The patient underwent a lateral orbitotomy and complete excision of the mass. The mass was not attached to the bone. Histopathologic and immunohistochemical examination confirmed the diagnosis of an EOS...
September 2016: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/27821914/spontaneous-extraskeletal-osteosarcoma-in-the-duodenum-of-a-crlj-cd1-icr-mouse
#10
Ryo Ando, Shinichiro Ikezaki, Yuko Yamaguchi, Kazutoshi Tamura, Toru Hoshiya
Extraskeletal osteosarcoma is a very rare tumor in humans and animals. This paper describes a case of extraskeletal osteosarcoma observed in the duodenum of a male ICR mouse. Grossly, a solid mass pushing up the tunica serosa was observed in the duodenal wall. Histologically, the tumor was located in the lamina propria mucosae and tela mucosa. Neoplastic cells densely proliferated in these areas, and replaced of the normal tissue components. A small amount of osteoid and a small clump of bone tissue were observed in the area of neoplastic cell proliferation, especially in the lamina propria mucosae...
October 2016: Journal of Toxicologic Pathology
https://www.readbyqxmd.com/read/27587886/treatment-of-extraskeletal-osteosarcoma-at-a-previous-injection-site-resulting-in-prolonged-survival-in-1-dog
#11
Laura E Selmic, Lynn R Griffin, Megan H Rector, Mary Lafferty, Roy Pool, Nicole P Ehrhart
A rare presentation of an extraskeletal osteosarcoma at a previous interscapular injection site in a dog is described. Treatment included surgical excision of the tumor followed by 6 rounds of intravenous carboplatin, oral toceranib, and cyclophosphamide. The dog survived for 20.5 months after diagnosis despite early development of pulmonary metastases.
September 2016: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/27561385/giant-cell-rich-osteosarcoma-of-the-parotid-gland-an-exceptionally-rare-entity-at-an-unusual-site
#12
Eric C Huang, Varand Ghazikhanian, Xiaohua Qian
Giant cell-rich osteosarcoma is a rare histologic variant of conventional osteosarcoma that affects mainly the extremities. Extraskeletal giant cell-rich osteosarcoma is therefore exceedingly rare. Here, we report the first case of this uncommon tumor involving the parotid gland in a 62-year-old male who presented with initial right jaw swelling. Radiologic work-up revealed a 6.2 cm mass involving the right parotid gland. Fine-needle aspiration cytology showed numerous multinucleated giant cells in a background of dyshesive epithelioid cells and rare clusters of spindle stromal cells, suspicious for malignancy...
December 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27539718/concurrent-nontuberculous-mycobacteria-infection-and-high-grade-anterior-mediastinal-extraskeletal-osteosarcoma-esos-is-there-a-connection
#13
Gabriel T Faz, Mahmoud Eltorky, Bernard Karnath
BACKGROUND Extraskeletal osteosarcomas (ESOS) of the mediastinum are extremely rare and may present with concurrent nontuberculous mycobacteria infection. CASE REPORT We present the second documented case of high-grade anterior mediastinal extraskeletal osteosarcoma in a 59-year-old man with a history of treated, latent tuberculosis (TB). Sputum samples grew Mycoplasma avium complex and Mycobacterium fortuitum. Imaging showed a right-sided 7.6 cm mass with compression of the main bronchus. Subsequent biopsy with vimentin staining established the diagnosis of ESOS...
August 19, 2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27528844/the-treatment-and-outcomes-of-extraskeletal-osteosarcoma-institutional-experience-and-review-of-the-literature
#14
Lukas M Nystrom, Nickolas B Reimer, John D Reith, Mark T Scarborough, C Parker Gibbs
BACKGROUND: Extraskeletal osteosarcoma is a rare tumor with a poor prognosis. The purpose of this study is to examine the oncologic outcomes of this disease as they relate to surgical treatment and use of adjuvant therapies. METHODS: We retrospectively analyzed all patients treated at our institution for high-grade extraskeletal osteosarcoma of the limb or chest wall. We recorded demographic data, presenting stage, surgical margin, use of adjuvant chemotherapy or radiation, incidence of local recurrence, metastases, and death...
2016: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/27509713/primary-extraskeletal-osteosarcoma-of-gall-bladder
#15
Gaurav P S Gahlot, Maitrayee Roy, Hemant Jain, Nihar Ranjan Dash, K S Madhusudhan, Vaishali Suri, Rajni Yadav, Prasenjit Das
No abstract text is available yet for this article.
October 2015: Tropical Gastroenterology: Official Journal of the Digestive Diseases Foundation
https://www.readbyqxmd.com/read/27499911/the-molecular-landscape-of-extraskeletal-osteosarcoma-a-clinicopathological-and-molecular-biomarker-study
#16
George Jour, Lu Wang, Sumit Middha, Ahmet Zehir, Wen Chen, Justyna Sadowska, John Healey, Narasimhan P Agaram, Lisa Choi, Khedoudja Nafa, Meera Hameed
Extraskeletal osteosarcoma (ESOSA) is a rare soft tissue neoplasm representing <5% of osteosarcomas and <1% of all soft-tissue sarcomas. Herein, we investigate the clinicopathological and molecular features of ESOSA and explore potential parameters that may affect outcome. Thirty-two cases were retrieved and histomorphology was reviewed. Clinical history and follow-up were obtained through electronic record review. DNA from formalin-fixed paraffin-embedded (FFPE) tissue was extracted and processed from 27 cases...
January 2016: Journal of Pathology. Clinical Research
https://www.readbyqxmd.com/read/27489434/fibro-osseous-pseudotumor-of-the-digit-a-diagnostic-pitfall-of-extraskeletal-osteosarcoma
#17
Kwang-Hyun Choi, Ji Sook You, Joon Won Huh, Young-In Jeong, Min Soo Kim, Mihn Sook Jue, Hyang-Joon Park
No abstract text is available yet for this article.
August 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27386494/primary-extraskeletal-pleural-osteosarcoma-a-rare-pleural-identity
#18
Hannah Copeland, Peter B Makdisi, Michael Duncan, Thomas C Wozniak, George Makdisi
A 69-year-old female with a history of a heart transplant 16 years prior, presented with a large left chest mass identified on fluoroscopy in the cardiac catheterization lab. The patient noted a 40 pound weight loss in one year. A chest X-ray (CXR) and chest computed tomography (CT) demonstrated a large complex cystic mass in the left chest. A CT guided aspiration was performed, and the cytology for the cyst fluid was negative for malignancy. The patient continued to have worsening shortness of breath, a repeat chest CT scan and magnetic resonance imaging (MRI) three months later, demonstrated a recurrence of the left pleural mass...
June 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27357312/subcutaneous-extraskeletal-osteosarcoma-of-the-forearm-a-case-report-and-review-of-the-literature
#19
Christopher Healy, Leonard B Kahn, Samuel Kenan
Extraskeletal osteosarcoma (ESOS) originating in the subcutaneous tissue is a rare occurrence, accounting for less than 10 % of ESOS cases. Osteosarcoma of extraskeletal origin accounts for approximately 2-4 % of all osteosarcomas, and 1 % of soft tissue sarcomas. We report a case of an 80-year-old female with an isolated primary subcutaneous tumor of the forearm. After imaging, surgical excision, and pathological analysis, the diagnosis of a subcutaneous osteosarcoma was made. This report documents the clinical and pathological findings of subcutaneous ESOS in this case, along with a review of previous cases of subcutaneous ESOS...
September 2016: Skeletal Radiology
https://www.readbyqxmd.com/read/26998347/solitary-synovial-chondromatosis-arising-in-the-gluteus-maximus-bursa-computed-tomography-and-magnetic-resonance-imaging-findings
#20
Kaoru Sumida, Noriko Kobayashi, Atsushi Nambu, Masao Tago, Isao Shibuya, Masashi Kawamoto
Chondral tumors in soft tissue are referred to as soft-tissue chondromas or extraskeletal chondromas, or as synovial chondromatosis if they arise in synovial tissue. We report the case of a 29-year-old man with synovial chondromatosis, also called synovial osteochondromatosis, which appeared in a solitary and extra-articular form. On magnetic resonance imaging (MRI) and computed tomography, the central portion of the tumor showed similar characteristics to bone marrow, despite the absence of any connection to adjacent bone...
March 2016: Acta Radiologica Open
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