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Bryan T. Kelly

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https://www.readbyqxmd.com/read/28504915/prevalence-of-os-styloideum-in-national-hockey-league-players
#1
Harry G Greditzer, Ian D Hutchinson, Christian S Geannette, Robert N Hotchkiss, Bryan T Kelly, Hollis G Potter
BACKGROUND: Os styloideum describes an accessory carpal ossicle between the trapezoid, the capitate, and the second and third metacarpals. Injuries to this tissue have been described as part of the carpal boss syndrome. While the etiology of os styloideum remains uncertain, it may represent a physiologic response to altered loading forces in the wrist, similar to the development of cam-type deformity in the hips of ice hockey players or the Bennett lesion in the shoulders of baseball pitchers...
May 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28420300/epinephrine-induced-pulmonary-edema-during-hip-arthroscopy-a-report-of-two-cases-and-a-review-of-the-literature
#2
Nicole S Belkin, Ryan M Degen, Gregory A Liguori, Bryan T Kelly
OBJECTIVES: Hip arthroscopy utilization has significantly increased in recent years. While it is a relatively safe procedure, it is not without risk. Life-threatening complications, albeit rare, can potentially occur and must be appropriately recognized and treated. We describe 2 cases in which patients' undergoing hip arthroscopy developed pulmonary edema and their respective courses of treatment. METHODS: Both patients were being treated for symptomatic femoroacetabular impingement (FAI), with labral tears, requiring operative management after a failed trial of conservative management...
April 26, 2017: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/28412058/functional-outcomes-and-cam-recurrence-after-arthroscopic-treatment-of-femoroacetabular-impingement-in-adolescents
#3
Ryan M Degen, Stephanie W Mayer, Kara G Fields, Struan H Coleman, Bryan T Kelly, Danyal H Nawabi
PURPOSE: To compare the functional outcomes after arthroscopic treatment of femoroacetabular impingement (FAI) in adolescent patients and non-adolescent patients, and to report on the rate of cam recurrence within 2 years after femoral osteoplasty in a limited sample of the adolescent group. METHODS: From 2010 to 2014, patients younger than 18 years with symptomatic FAI (alpha angle >50°) who underwent hip arthroscopy with minimum 2-year follow-up or reoperation were identified...
April 12, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28298057/defining-the-substantial-clinical-benefit-after-arthroscopic-treatment-of-femoroacetabular-impingement
#4
Benedict U Nwachukwu, Brenda Chang, Kara Fields, Brian J Rebolledo, Danyal H Nawabi, Bryan T Kelly, Anil S Ranawat
BACKGROUND: The minimal clinically important difference (MCID) has been defined in orthopaedics and is the smallest change that a patient considers meaningful. Less is known about improvements that the patient perceives as clinically considerable, or the substantial clinical benefit (SCB). For the young, highly functioning patient cohort with femoroacetabular impingement (FAI), the SCB is an important measure of clinical success. PURPOSE: To derive the SCB for FAI treatment and identify outcome score thresholds and patient variables predictive of the SCB...
May 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28163793/uromark-a-urinary-biomarker-assay-for-the-detection-of-bladder-cancer
#5
Andrew Feber, Pawan Dhami, Liqin Dong, Patricia de Winter, Wei Shen Tan, Mónica Martínez-Fernández, Dirk S Paul, Antony Hynes-Allen, Sheida Rezaee, Pratik Gurung, Simon Rodney, Ahmed Mehmood, Felipe Villacampa, Federico de la Rosa, Charles Jameson, Kar Keung Cheng, Maurice P Zeegers, Richard T Bryan, Nicholas D James, Jesus M Paramio, Alex Freeman, Stephan Beck, John D Kelly
BACKGROUND: Bladder cancer (BC) is one of the most common cancers in the western world and ranks as the most expensive to manage, due to the need for cystoscopic examination. BC shows frequent changes in DNA methylation, and several studies have shown the potential utility of urinary biomarkers by detecting epigenetic alterations in voided urine. The aim of this study is to develop a targeted bisulfite next-generation sequencing assay to diagnose BC from urine with high sensitivity and specificity...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28049596/hip-preservation-surgery-expectations-survey-a-new-method-to-measure-patients-preoperative-expectations
#6
Carol A Mancuso, Catherine H Wentzel, Hassan M K Ghomrawi, Bryan T Kelly
PURPOSE: To develop a patient-derived expectations survey for hip preservation surgery. METHODS: Patients were eligible if they were undergoing primary hip surgery and were recruited in person or by telephone. The survey was developed in 3 phases. During phase 1, 64 patients were interviewed preoperatively and asked open-ended questions about their expectations of surgery; a draft survey was assembled by categorizing responses. During phase 2, the survey was administered twice to another group of 50 patients preoperatively to assess test-retest reliability and concordance was measured with weighted kappa values and intraclass correlations...
December 31, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28049594/anterior-inferior-iliac-spine-morphology-and-outcomes-of-hip-arthroscopy-in-soccer-athletes-a%C3%A2-comparison-to-nonkicking-athletes
#7
Danyal H Nawabi, Ryan M Degen, Kara G Fields, Catherine S Wentzel, Olusanjo Adeoye, Bryan T Kelly
PURPOSE: To describe the anterior inferior iliac spine (AIIS) morphology and clinical outcomes following arthroscopic surgical decompression in a group of high-level soccer athletes presenting with symptomatic hip impingement when compared with a control group of nonkicking athletes. METHODS: From 2009 to 2012, we retrospectively reviewed our prospective hip registry for soccer athletes who underwent arthroscopic treatment for femoroacetabular impingement (FAI) with 2-year follow-up, comparing with a control group of nonkicking athletes...
December 31, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/27927616/safety-of-hip-anchor-insertion-from-the-midanterior-and-distal-anterolateral-portals-with-a-straight-drill-guide
#8
Ryan M Degen, Lazaros Poultsides, Stephanie W Mayer, Angela E Li, Struan H Coleman, Anil S Ranawat, Danyal H Nawabi, Bryan T Kelly
BACKGROUND: During arthroscopic labral refixation, suture anchors are typically inserted from either the midanterior (MA) portal or the distal anterolateral (DALA) portal; however, no studies have previously compared these techniques. Purpose/Hypothesis: The purpose of this study was to compare acetabular rim accessibility and associated complication rates of anchor insertion from these portals. We hypothesized that rim access would be better from the DALA portal. Additionally, we hypothesized that articular surface perforation would occur more commonly from the MA portal while psoas tunnel perforation would occur more commonly from the DALA portal...
March 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27920671/proceedings-of-the-fourth-annual-deep-brain-stimulation-think-tank-a-review-of-emerging-issues-and-technologies
#9
Wissam Deeb, James J Giordano, Peter J Rossi, Alon Y Mogilner, Aysegul Gunduz, Jack W Judy, Bryan T Klassen, Christopher R Butson, Craig Van Horne, Damiaan Deny, Darin D Dougherty, David Rowell, Greg A Gerhardt, Gwenn S Smith, Francisco A Ponce, Harrison C Walker, Helen M Bronte-Stewart, Helen S Mayberg, Howard J Chizeck, Jean-Philippe Langevin, Jens Volkmann, Jill L Ostrem, Jonathan B Shute, Joohi Jimenez-Shahed, Kelly D Foote, Aparna Wagle Shukla, Marvin A Rossi, Michael Oh, Michael Pourfar, Paul B Rosenberg, Peter A Silburn, Coralie de Hemptine, Philip A Starr, Timothy Denison, Umer Akbar, Warren M Grill, Michael S Okun
This paper provides an overview of current progress in the technological advances and the use of deep brain stimulation (DBS) to treat neurological and neuropsychiatric disorders, as presented by participants of the Fourth Annual DBS Think Tank, which was convened in March 2016 in conjunction with the Center for Movement Disorders and Neurorestoration at the University of Florida, Gainesveille FL, USA. The Think Tank discussions first focused on policy and advocacy in DBS research and clinical practice, formation of registries, and issues involving the use of DBS in the treatment of Tourette Syndrome...
2016: Frontiers in Integrative Neuroscience
https://www.readbyqxmd.com/read/27883049/mqc-a-heuristic-quality-control-metric-for-high-throughput-drug-combination-screening
#10
Lu Chen, Kelli Wilson, Ian Goldlust, Bryan T Mott, Richard Eastman, Mindy I Davis, Xiaohu Zhang, Crystal McKnight, Carleen Klumpp-Thomas, Paul Shinn, John Simmons, Mike Gormally, Sam Michael, Craig J Thomas, Marc Ferrer, Rajarshi Guha
Quality control (QC) metrics are critical in high throughput screening (HTS) platforms to ensure reliability and confidence in assay data and downstream analyses. Most reported HTS QC metrics are designed for plate level or single well level analysis. With the advent of high throughput combination screening there is a need for QC metrics that quantify the quality of combination response matrices. We introduce a predictive, interpretable, matrix-level QC metric, mQC, based on a mix of data-derived and heuristic features...
November 24, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27791238/complications-and-short-term-patient-outcomes-of-periacetabular-osteotomy-for-symptomatic-mild-hip-dysplasia
#11
Benjamin F Ricciardi, Kara G Fields, Catherine Wentzel, Danyal H Nawabi, Bryan T Kelly, Ernest L Sink
INTRODUCTION: The purpose of our study is to identify complications and early functional outcome scores in patients treated with periacetabular osteotomy (PAO) for mild acetabular dysplasia. METHODS: The study population consisted of patients from a single centre prospective hip registry undergoing PAO with mild acetabular dysplasia (LCEA ≥18° and ≤25°; n = 27 patients; Mild Dysplasia group). A comparison group of patients undergoing PAO with more severe acetabular dysplasia (lateral centre-edge angle [LCEA] ≤17°; n = 50 patients; Severe Dysplasia group) were included as a comparison cohort...
October 24, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27765733/preoperative-outcome-scores-are-predictive-of-achieving-the-minimal-clinically-important-difference-after-arthroscopic-treatment-of-femoroacetabular-impingement
#12
Benedict U Nwachukwu, Kara Fields, Brenda Chang, Danyal H Nawabi, Bryan T Kelly, Anil S Ranawat
BACKGROUND: There is increasing interest in defining meaningful improvement in patient-reported outcomes. Knowledge of the thresholds and determinants for successful femoroacetabular impingement (FAI) outcomes is evolving. PURPOSE: To define preoperative outcome score thresholds and determine clinical/demographic patient factors predictive for achieving the minimal clinically important difference (MCID) after arthroscopic FAI surgery. STUDY DESIGN: Cohort study (diagnosis); Level of evidence, 2...
March 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/27734165/medication-adherence-in-patients-with-myotonic-dystrophy-and-facioscapulohumeral-muscular-dystrophy
#13
Bryan P Fitzgerald, Kelly M Conn, Joanne Smith, Andrew Walker, Amy L Parkhill, James E Hilbert, Elizabeth A Luebbe, Richard T Moxley
Myotonic dystrophy (DM) and facioscapulohumeral muscular dystrophy (FSHD) are the two most common adult muscular dystrophies and have progressive and often disabling manifestations. Higher levels of medication adherence lead to better health outcomes, especially important to patients with DM and FSHD because of their multisystem manifestations and complexity of care. However, medication adherence has not previously been studied in a large cohort of DM type 1 (DM1), DM type 2 (DM2), and FSHD patients. The purpose of our study was to survey medication adherence and disease manifestations in patients enrolled in the NIH-supported National DM and FSHD Registry...
December 2016: Journal of Neurology
https://www.readbyqxmd.com/read/27688219/strengthening-health-systems-while-responding-to-a-health-crisis-lessons-learned-by-a-nongovernmental-organization-during-the-ebola-virus-disease-epidemic-in-sierra-leone
#14
Corrado Cancedda, Sheila M Davis, Kerry L Dierberg, Jonathan Lascher, J Daniel Kelly, Mohammed Bailor Barrie, Alimamy Philip Koroma, Peter George, Adikali Alpha Kamara, Ronald Marsh, Manso S Sumbuya, Cameron T Nutt, Kirstin W Scott, Edgar Thomas, Katherine Bollbach, Andrew Sesay, Ahmidu Barrie, Elizabeth Barrera, Kathryn Barron, John Welch, Nahid Bhadelia, Raphael G Frankfurter, Ophelia M Dahl, Sarthak Das, Rebecca E Rollins, Bryan Eustis, Amanda Schwartz, Piero Pertile, Ilias Pavlopoulos, Allan Mayfield, Regan H Marsh, Yusupha Dibba, Danielle Kloepper, Andrew Hall, Karin Huster, Michael Grady, Kimberly Spray, David A Walton, Fodei Daboh, Cora Nally, Sahr James, Gabriel S Warren, Joyce Chang, Michael Drasher, Gina Lamin, Sherry Bangura, Ann C Miller, Annie P Michaelis, Ryan McBain, M Jana Broadhurst, Megan Murray, Eugene T Richardson, Ted Philip, Gary L Gottlieb, Joia S Mukherjee, Paul E Farmer
An epidemic of Ebola virus disease (EVD) beginning in 2013 has claimed an estimated 11 310 lives in West Africa. As the EVD epidemic subsides, it is important for all who participated in the emergency Ebola response to reflect on strengths and weaknesses of the response. Such reflections should take into account perspectives not usually included in peer-reviewed publications and after-action reports, including those from the public sector, nongovernmental organizations (NGOs), survivors of Ebola, and Ebola-affected households and communities...
October 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27559122/incidence-of-aids-defining-opportunistic-infections-in-a-multicohort-analysis-of-hiv-infected-persons-in-the-united-states-and-canada-2000-2010
#15
Kate Buchacz, Bryan Lau, Yuezhou Jing, Ronald Bosch, Alison G Abraham, M John Gill, Michael J Silverberg, James J Goedert, Timothy R Sterling, Keri N Althoff, Jeffrey N Martin, Greer Burkholder, Neel Gandhi, Hasina Samji, Pragna Patel, Anita Rachlis, Jennifer E Thorne, Sonia Napravnik, Keith Henry, Angel Mayor, Kelly Gebo, Stephen J Gange, Richard D Moore, John T Brooks
BACKGROUND: There are few recent data on the rates of AIDS-defining opportunistic infections (OIs) among human immunodeficiency virus (HIV)-infected patients in care in the United States and Canada. METHODS: We studied HIV-infected participants in 16 cohorts in the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) during 2000-2010. After excluding 16 737 (21%) with any AIDS-defining clinical events documented before NA-ACCORD enrollment, we analyzed incident OIs among the remaining 63 541 persons, most of whom received antiretroviral therapy during the observation...
September 15, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27551733/diagnosis-of-intraabdominal-fluid-extravasation-after-hip-arthroscopy-with-point-of-care-ultrasonography-can-identify-patients-at-an-increased-risk-for-postoperative-pain
#16
Stephen C Haskins, Natasha A Desai, Kara G Fields, Jemiel A Nejim, Stephanie Cheng, Struan H Coleman, Danyal H Nawabi, Bryan T Kelly
BACKGROUND: Intraabdominal fluid extravasation (IAFE) after hip arthroscopy has historically been diagnosed in catastrophic circumstances with abdominal compartment syndrome requiring diuresis or surgical decompression. A previous retrospective study found the prevalence of symptomatic IAFE requiring diuresis or decompression to be 0.16%, with risk factors including surgical procedure and high pump pressures. IAFE can be diagnosed rapidly by using point-of-care ultrasound (POCUS) via the Focused Assessment With Sonography for Trauma (FAST) examination, which is a well-established means to detect free fluid with high specificity and sensitivity...
March 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27539130/return-to-play-rates-following-arthroscopic-treatment-of-femoroacetabular-impingement-in-competitive-baseball-players
#17
Ryan M Degen, Kara G Fields, C Sally Wentzel, Bethanne Bartscherer, Anil S Ranawat, Struan H Coleman, Bryan T Kelly
OBJECTIVE: Femoroacetabular impingement (FAI) has been increasingly recognized in cutting sports including soccer, hockey and football. More recently, the prevalence among overhead athletes has also been recognized. The purpose of this study was to review impingement patterns, return-to-play rates and clinical outcome following arthroscopic treatment of FAI among high-level baseball players. METHODS: Between 2010 and 2014, 70 competitive baseball players (86 hips; age 22...
November 2016: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/27490671/arthroscopic-treatment-of-cam-type-impingement-of-the-hip
#18
Christopher Kweon, K Linnea Welton, Bryan T Kelly, Christopher M Larson, Asheesh Bedi
No abstract text is available yet for this article.
September 15, 2015: JBJS Reviews
https://www.readbyqxmd.com/read/27490474/arthroscopic-treatment-of-pincer-type-impingement-of-the-hip
#19
Eileen A Crawford, K Linnea Welton, Christopher Kweon, Bryan T Kelly, Christopher M Larson, Asheesh Bedi
No abstract text is available yet for this article.
August 25, 2015: JBJS Reviews
https://www.readbyqxmd.com/read/27416990/patient-characteristics-and-early-functional-outcomes-of-combined-arthroscopic-labral-refixation-and-periacetabular-osteotomy-for-symptomatic-acetabular-dysplasia
#20
Benjamin F Ricciardi, Stephanie W Mayer, Kara G Fields, Catherine Wentzel, Bryan T Kelly, Ernest L Sink
BACKGROUND: Symptomatic labral tears are common in patients with acetabular dysplasia; however, optimal treatment of the labrum remains controversial. PURPOSE: To present patient characteristics and early functional outcomes associated with combined arthroscopic labral refixation and Bernese periacetabular osteotomy (PAO) for symptomatic acetabular dysplasia with a displaced labral tear from the acetabular rim. STUDY DESIGN: Cohort study; Level of evidence, 3...
October 2016: American Journal of Sports Medicine
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