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https://www.readbyqxmd.com/read/29050032/providing-personalised-nutrition-consumers-trust-and-preferences-regarding-sources-of-information-service-providers-and-regulators-and-communication-channels
#1
Rui Poínhos, Bruno M P M Oliveira, Ivo A van der Lans, Arnout R H Fischer, Aleksandra Berezowska, Audrey Rankin, Sharron Kuznesof, Barbara Stewart-Knox, Lynn J Frewer, Maria D V de Almeida
BACKGROUND/AIMS: Personalised nutrition has potential to revolutionise dietary health promotion if accepted by the general public. We studied trust and preferences regarding personalised nutrition services, how they influence intention to adopt these services, and cultural and social differences therein. METHODS: A total of 9,381 participants were quota-sampled to be representative of each of 9 EU countries (Germany, Greece, Ireland, Poland, Portugal, Spain, the Netherlands, the UK, and Norway) and surveyed by a questionnaire assessing their intention to adopt personalised nutrition, trust in service regulators and information sources, and preferences for service providers and information channels...
October 20, 2017: Public Health Genomics
https://www.readbyqxmd.com/read/29048667/inhibitory-effect-of-black-tea-pigments-theaflavin%C3%A2-3-3-gallate-against-cisplatin-resistant-ovarian-cancer-cells-by-inducing-apoptosis-and-g1-cell-cycle-arrest
#2
Haibo Pan, Fang Wang, Gary O Rankin, Yon Rojanasakul, Youying Tu, Yi Charlie Chen
Adverse side effects and acquired resistance to conventional chemotherapy based on platinum drive the exploration of other selective anticancer drugs. Theaflavin‑3-gallate (TF2a) and theaflavin‑3'-gallate (TF2b), theaflavin monomers in black tea, exhibited a potent growth inhibitory effect on cisplatin-resistant ovarian cancer A2780/CP70 cells and were less cytotoxic to normal ovarian IOSE-364 cell line. Flow cytometry analysis and western blotting indicated that TF2a and TF2b induced apoptosis and G1 cell cycle arrest in ovarian cancer A2780/CP70 cells...
October 3, 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/29048201/hygienic-shortcomings-of-frozen-dessert-freezing-equipment-and-fate-of-listeria-monocytogenes-on-ice-cream-soiled-stainless-steel
#3
A Inuwa, A Lunt, C Czuprynski, G Miller, S A Rankin
Although frozen dairy desserts have a strong record of safety, recent outbreaks of foodborne disease linked to ice creams have brought new attention to this industry. There is concern that small-scale frozen dessert equipment may not comply with or be reviewed against published comprehensive design and construction sanitation specifications (National Sanitation Foundation or 3-A sanitary standards). Equipment sanitary design issues may result in reduced efficacy of cleaning and sanitation, thus increasing the likelihood of postprocess contamination with pathogenic bacteria...
October 19, 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/29046918/flow-diverter-treatment-of-cerebral-blister-aneurysms
#4
Russell Cerejo, Mark Bain, Seby John, Julian Hardman, Nina Moore, M Shazam Hussain, Gabor Toth
PURPOSE: Blood blister-like aneurysms (BBA) are small, friable, broad-based aneurysms that represent high risk for rerupture. Treatment of BBA is challenging, and may include surgical wrapping, clipping, multiple overlapping stents, and/or coiling. Flow diversion is a rapidly evolving treatment strategy for intracranial aneurysms, but the evidence for its use in cases of BBA is scarce. METHODS: A retrospective review of flow-diverter-treated, ruptured BBA cases at our tertiary care institution was undertaken...
October 18, 2017: Neuroradiology
https://www.readbyqxmd.com/read/29043564/the-ucp2-866g-a-polymorphism-could-be-considered-as-a-genetic-marker-of-different-functional-prognosis-in-ischemic-stroke-after-recanalization
#5
I Díaz-Maroto Cicuéndez, E Fernández-Díaz, J García-García, J Jordán, I Fernández-Cadenas, J Montaner, G Serrano-Heras, T Segura
Recent studies based on experimental animal models of stroke have suggested that uncoupling protein 2 (UCP2), an inner mitochondrial membrane protein that is thought to regulate energy metabolism and reduce reactive oxygen species generation, provides protection against reperfusion damage. We aimed to investigate whether -866G/A polymorphism in the promoter of the UCP2 gene, which enhances its transcriptional activity, is associated with functional prognosis in patients with embolic ischemic stroke after early recanalization...
October 17, 2017: Neuromolecular Medicine
https://www.readbyqxmd.com/read/29042878/the-evaluation-acute-traumatic-stress-level-in-close-relatives-of-stroke-patients
#6
Yasemin Ünal, Yes Im Ünal, Dilek A Öztürk, Gülser K Emir, Mustafa Yılmaz, Gulnihal Kutlu
OBJECTIVE: Stroke is the second most common cause of death and the leading cause of adult disability. Both stroke patients and their family can therefore experience increased traumatic stress level. METHODS: The participants are close relatives of patients (n=65) who had a first time stroke (CRPWS) hospitalized. A control group (CG) (n=61), who had no history of chronic illness in their family and had at least one traumatic life event experience. The National Institutes of Health Stroke Scale, Modified Rankin Scale, Personal Information Form, Life Events Checklist, Traumatic Stress Symptom Scale, and Multidimensional Scale of Perceived Social Support, were used in the study...
September 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29042780/frequencies-of-circulating-b-and-t-lymphocytes-as-indicators-for-stroke-outcomes
#7
Yanling Wang, Jihong Liu, Xuemei Wang, Zongjian Liu, Fengwu Li, Fenghua Chen, Xiaokun Geng, Zhili Ji, Huishan Du, Xiaoming Hu
BACKGROUND: Stroke has high mortality and morbidity. Biomarkers are required for to predict stroke outcomes, which could help clinicians to provide rationale approaches for patient management. The dynamic changes in circulating immune cells have been reported in stroke patients and animal models of stroke. AIM: The aim of this study was to explore biomarkers to predict stroke outcomes by investigating the relationship between the frequencies of circulating immune cells and stroke outcomes...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29039275/visuospatial-functioning-in-the-primary-progressive-aphasias
#8
Christa L Watson, Katherine Possin, I Elaine Allen, H Isabel Hubbard, Marita Meyer, Ariane E Welch, Gil D Rabinovici, Howard Rosen, Katherine P Rankin, Zachary Miller, Miguel A Santos-Santos, Joel H Kramer, Bruce L Miller, Maria Luisa Gorno-Tempini
OBJECTIVES: The aim of this study was to identify whether the three main primary progressive aphasia (PPA) variants would show differential profiles on measures of visuospatial cognition. We hypothesized that the logopenic variant would have the most difficulty across tasks requiring visuospatial and visual memory abilities. METHODS: PPA patients (n=156), diagnosed using current criteria, and controls were tested on a battery of tests tapping different aspects of visuospatial cognition...
October 17, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29038080/a-stent-retrieving-into-an-aspiration-catheter-with-proximal-balloon-asap-technique-a-technique-of-mechanical-thrombectomy
#9
Shunsaku Goto, Tomotaka Ohshima, Kojiro Ishikawa, Taiki Yamamoto, Shinji Shimato, Toshihisa Nishizawa, Kyozo Kato
PURPOSE: The best technique for the first attempt at mechanical thrombectomy for acute ischemic stroke is a still matter of debate. In this study, we evaluated the efficacy of a stent-retrieving into an aspiration catheter with proximal balloon (ASAP) technique that employs a series of thrombus extraction by withdrawing the stent retriever into the aspiration catheter, and continuous aspiration from the aspiration catheter in the first attempt. METHODS: We performed a retrospective analysis of 42 consecutive patients with acute ischemic stroke caused by occlusions in the anterior circulation, who were treated with the ASAP technique at our institution...
October 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29037758/the-association-of-vertebrobasilar-calcification-with-etiological-subtypes-stroke-recurrence-and-outcome-in-acute-brainstem-ischemic-stroke
#10
Elif Gökçal, Elvin Niftaliyev, Tuğçe Özdemir, Mehmet Kolukısa, Talip Asil
Arterial calcification (AC), a frequent finding on imaging studies, has been reported as a risk factor for ischemic stroke. However few studies have explored the association of AC with etiological subtypes and prognostic implications. The purpose of this study was to investigate the association of AC with demograhics, risk factors and etiological subtypes and to determine whether it predicts stroke recurrence and functional outcome in patients with acute brainstem ischemic stroke. We analyzed our database consisting of patients who were diagnosed as acute brainstem ischemic stroke admitted within 24hours of onset...
October 9, 2017: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29037226/xingnaojing-for-moderate-to-severe-acute-ischemic-stroke-xmas-study-protocol-for-a-randomized-controlled-trial
#11
Xinxing Lai, Kegang Cao, Lingbo Kong, Qiang Liu, Ying Gao
BACKGROUND: Xingnaojing injection (XNJ) is widely used for the treatment of stroke in China. However, there is currently a lack of high-quality evidence of its efficacy for acute ischemic stroke. The main objective of this study is to determine whether the addition of XNJ to standard care improves the 3-month functional outcome in patients with acute ischemic stroke (AIS). METHODS/DESIGN: The XMAS study is a multicenter, prospective, randomized controlled, open-label trial with a blinded endpoints design...
October 16, 2017: Trials
https://www.readbyqxmd.com/read/29037015/comparison-of-spot-sign-blend-sign-and-black-hole-sign-for-outcome-prediction-in-patients-with-intracerebral-hemorrhage
#12
Peter B Sporns, Michael Schwake, André Kemmling, Jens Minnerup, Wolfram Schwindt, Thomas Niederstadt, Rene Schmidt, Uta Hanning
BACKGROUND AND PURPOSE: Blend sign (BS) and black hole sign (BHS) on non-contrast computed tomography (NCCT) and spot sign (SS) on CT-angiography (CTA) are indicators of early hematoma expansion in spontaneous intracerebral hemorrhage (ICH). However, their independent contributions to outcome have not been well explored. METHODS: In this retrospective study, inclusion criteria were: 1) spontaneous ICH and 2) NCCT and CTA performed on admission within 6 hours after onset of symptoms...
September 2017: Journal of Stroke
https://www.readbyqxmd.com/read/29037006/microrna-150-5p-improves-risk-classification-for-mortality-within-90-days-after-acute-ischemic-stroke
#13
Natalie Scherrer, Francois Fays, Beat Mueller, Andreas Luft, Felix Fluri, Mirjam Christ-Crain, Yvan Devaux, Mira Katan
BACKGROUND AND PURPOSE: Micro ribonucleic acid-150-5p (miR-150-5p) regulates proinflammatory cytokines as well as vessel integrity. We evaluated the incremental prognostic value of logarithm (log) of miR-150-5p plasma levels after ischemic stroke. METHODS: In a prospective cohort study, levels of miR-150-5p were measured within 72 hours of symptom onset in 329 ischemic stroke patients. The outcome measures were unfavorable functional outcome (assessed by the modified Rankin Scale score >2) and mortality within 90 days...
September 2017: Journal of Stroke
https://www.readbyqxmd.com/read/29033392/mechanical-recanalization-in-ischemic-anterior-circulation-stroke-within-an-8-hour-time-window-a-real-world-experience
#14
Dagmar Krajíčková, Antonín Krajina, Roman Herzig, Miroslav Lojík, Vendelín Chovanec, Jan Raupach, Eva Vítková, Jan Waishaupt, Oldřich Vyšata, Martin Vališ
PURPOSE: We aimed to assess the safety and effectiveness of mechanical recanalization in patients with ischemic stroke in the anterior circulation within 8 h since symptoms onset and with unknown onset time. We compared time intervals <6 h vs. 6-8 h/unknown onset time, as only limited data are available for a time window beyond 6 h. METHODS: Our cohort included 110 consecutive patients (44 males; mean age, 73.0±11.5 years) with ischemic stroke in the anterior circulation due to the acute occlusion of a large intracranial artery who underwent mechanical recanalization within an 8-hour time window or with unknown onset time...
October 16, 2017: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/29033375/intraprocedural-arterial-perforation-during-neuroendovascular-therapy-preliminary-result-of-a-dual-trained-endovascular-neurosurgeon-in-the-neurosurgical-hybrid-operating-room
#15
Yuang-Seng Tsuei, Chih-Hsiang Liao, Chung-Hsin Lee, Yea-Jiuan Liang, Wen-Hsien Chen, Shun-Fa Yang
BACKGROUND: Intraprocedural arterial perforation (IPAP) is a potentially dismal complication of neuroendovascular therapy with high mortality and morbidity rates. The management of IPAP with the techniques described has been well established, but rescue results from the dual-trained endovascular neurosurgeon in the neurosurgical hybrid operating room (OR) are rarely reported. Here, we report five cases of successful rescue of IPAP in the neurosurgical hybrid OR and compare them with other series...
October 12, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29033109/three-years-of-the-nationwide-post-acute-stroke-care-program-in-taiwan
#16
Cheng-Yang Hsieh, Wei-Chia Tsao, Ruey-Tay Lin, A-Ching Chao
Prolonged hospital stay and readmission are prevalent problems for stroke patients in Taiwan after the acute stage, partly due to the unmet need of post-acute care. In March 2014, Taiwan's National Health Insurance Administration launched a nationwide Post-Acute Care-CerebroVascular Disease (PAC-CVD) program. The Taiwan Stroke Society, coordinating 11 allied disciplines, took responsibility for the preparation and implementation of the program. As of June 2016, 6839 consecutive stroke patients were enrolled...
October 9, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29031498/low-free-triiodothyronine-at-admission-predicts-poststroke-infection
#17
Satoshi Suda, Junya Aoki, Takashi Shimoyama, Kentaro Suzuki, Yuki Sakamoto, Takehiro Katano, Seiji Okubo, Chikako Nito, Yasuhiro Nishiyama, Masahiro Mishina, Kazumi Kimura
BACKGROUND: Poststroke infection (PSI) is common and is usually associated with a severe prognosis. We investigated the association between PSI and thyroid hormones, which are critical to immune regulation, in patients with acute stroke. METHODS: We retrospectively enrolled 520 consecutive patients with acute ischemic stroke (326 men; age, 71.9 ± 13.2 years) admitted to our department between September 2014 and June 2016. The impact of serum thyroid hormone levels measured at admission (thyroid-stimulating hormone [TSH], free triiodothyronine [FT3], and free thyroxine [FT4]) on the PSI was evaluated using multivariate logistic regression analysis...
October 11, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29031484/effects-of-leucine-enriched-essential-amino-acid-and-whey-protein-bolus-dosing-upon-skeletal-muscle-protein-synthesis-at-rest-and-after-exercise-in-older-women
#18
Daniel J Wilkinson, Syed S I Bukhari, Bethan E Phillips, Marie C Limb, Jessica Cegielski, Matthew S Brook, Debbie Rankin, William K Mitchell, Hisamine Kobayashi, John P Williams, Jonathan Lund, Paul L Greenhaff, Kenneth Smith, Philip J Atherton
BACKGROUND & AIMS: Impaired anabolic responses to nutrition and exercise contribute to loss of skeletal muscle mass with ageing (sarcopenia). Here, we tested responses of muscle protein synthesis (MPS), in the under represented group of older women, to leucine-enriched essential amino acids (EAA) in comparison to a large bolus of whey protein (WP). METHODS: Twenty-four older women (65 ± 1 y) received (N = 8/group) 1.5 g leucine-enriched EAA supplements (LEAA_1...
September 23, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29030498/late-recanalization-of-basilar-artery-occlusion-in-a-previously-healthy-17-month-old-child
#19
D Andrew Wilkinson, Aditya S Pandey, Hugh J Garton, Luis Savastano, Julius Griauzde, Neeraj Chaudhary, Joseph J Gemmete
Endovascular treatment of acute ischemic stroke in children is increasingly being reported, although the time window for intervention is unclear. We describe a previously healthy 17-month-old child who presented with vertebral artery thrombosis and cerebellar stroke requiring posterior fossa decompression. She later progressed to basilar artery thrombosis treated with mechanical thrombectomy 50 hours after clinical decline. At 3 month follow-up, the patient had a modified Rankin Scale score of 0.
October 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29030478/randomized-controlled-trial-of-early-versus-delayed-statin-therapy-in-patients-with-acute-ischemic-stroke-assort-trial-administration-of-statin-on-acute-ischemic-stroke-patient
#20
Shinichi Yoshimura, Kazutaka Uchida, Takashi Daimon, Ryuzo Takashima, Kazuhiro Kimura, Takeshi Morimoto
BACKGROUND AND PURPOSE: Several studies suggested that statins during hospitalization were associated with better disability outcomes in patients with acute ischemic stroke, but only 1 small randomized trial is available. METHODS: We conducted a multicenter, open-label, randomized controlled trial in patients with acute ischemic strokes in 11 hospitals in Japan. Patients with acute ischemic stroke and dyslipidemia randomly received statins within 24 hours after admission in the early group or on the seventh day in the delayed group, in a 1:1 ratio...
October 13, 2017: Stroke; a Journal of Cerebral Circulation
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