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transient ischemic accident

Rokhsareh Meamar, Hamidreza Nikyar, Leila Dehghani, Maedeh Talebi, Marzieh Dehghani, Marzieh Ghasemi, Behnaz Ansari, Mohammad Saadatnia
BACKGROUND: The role of endothelial progenitor cells (EPCs) in the maintenance of vascularization following ischemic brain after experimental stroke has been established. Accordingly, in this study, we evaluated the role of circulating EPCs in transient ischemic attack (TIA) patients for future cerebrovascular (CV) events. MATERIALS AND METHODS: The level of circulating EPCs (staining markers: CD34, CD309) were determined using flow cytometry at 24 h after TIA in thirty consecutive patients...
2016: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
Vikas Aggarwal, Ehrin J Armstrong, Wenhui Liu, Thomas M Maddox, P Michael Ho, Evan Carey, Tracy Wang, Matthew Sherwood, Thomas T Tsai, John S Rumsfeld, Steven M Bradley
BACKGROUND: Prasugrel is more effective than clopidogrel in preventing thrombotic complications after percutaneous coronary intervention (PCI) among patients with acute coronary syndromes (ACS), but it increases the risk of bleeding in subgroups of patients. There is limited data on whether prasugrel use in routine practice is targeted to clinical settings with greatest anticipated patient benefit. METHODS: In a national cohort of 11 617 veterans who underwent PCI between 2010 and 2013 at Veterans Administration hospitals nationwide, we assessed overall trends in the use of prasugrel and the frequency of prasugrel use in patients with contraindications (prior transient ischemic attack or cerebrovascular accident), higher bleeding risk (age ≥75 or weight <60 kg), and nonindicated settings (non-acute coronary syndrome [non-ACS])...
October 2016: Clinical Cardiology
Saima Karim, Sweetheart T Ador-Dionisio, Munira Karim, Mohammad Karim, Sadaf S Khan, Ashish Atreja, Stephen Ellis
BACKGROUND: Little literature exists on the risk of performing coronary intervention (PCI) on patients who have had recent gastrointestinal bleeding (GIB), although bleeding after PCI has been identified as a risk factor for long-term mortality. METHODS: Patients within the Cleveland Clinic PCI database who had acute GIB within 30 days preceding PCI during the same hospitalization (n = 79) were retrospectively compared to those who had PCI without recent GIB (n = 10 979) for mortality and need for revascularization...
October 27, 2016: Acute Cardiac Care
F Aboukhoudir, I Aboukhoudir, O Rica, B Khennine, M Pansieri, S Rekik
Cor triatrium is a rare congenital heart disease typically diagnosed amongst very young patients. Delayed diagnosis in the elderly is much more unusual. We report the case of a 59-year-old male with unremarkable medical history in whom we have discovered, on an echocardiography performed for an exploration of transient ischemic accident with atrial fibrillation, a particular form of an isolated cor triatrium dextrum investigated with multimodality imaging.
September 28, 2016: Annales de Cardiologie et D'angéiologie
Linda Visser, Bas M Wallis de Vries, Douwe J Mulder, Maarten Uyttenboogaart, Sterre van der Veen, Clark J Zeebregts, Robert A Pol
The metabolic syndrome (MetS) is a cluster of risk factors for cardiovascular disease. The aim of this study is to determine the influence of MetS on short- and long-term outcome and survival after carotid endarterectomy (CEA). Between January 2005 and December 2014, data from all patients undergoing CEA were prospectively recorded. The metabolic syndrome was defined based on the presence of ≥3 of the following criteria: hypertension, high serum triglycerides, low levels of high-density lipoprotein cholesterol, high fasting serum glucose, and obesity...
August 29, 2016: Angiology
Tomás Francisco Cianciulli, Juan Bautista Soumoulou, Jorge Alberto Lax, María Cristina Saccheri, Alberto Cozzarin, Martín Alejandro Beck, Daniel Ernesto Ferreiro, Horacio Alberto Prezioso
INTRODUCTION: Papillary fibroelastoma (PFE) is a benign cardiac tumor that is currently detected more often due to the technological improvements in echocardiography. OBJECTIVES: To describe the echocardiographic features of PFE and correlate them with the clinical presentation and initial treatment. MATERIALS AND METHODS: A prospective analysis of patients with a diagnosis of PFE was conducted between 2000 and 2015. We assessed the clinical history, symptoms at the time of diagnosis, echocardiographic features, and initial treatment...
August 26, 2016: Echocardiography
Chin-Yu Lin, Shih-Lin Chang, Fa-Po Chung, Yun-Yu Chen, Yenn-Jiang Lin, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Tze-Fan Chao, Jo-Nan Liao, Yao-Ting Chang, Chung-Hsing Lin, Suresh Allamsetty, Rohit Walia, Abigail Louise D Te, Shinya Yamada, Shuo-Ju Chiang, Hsuan-Ming Tsao, Shih-Ann Chen
BACKGROUND: The impact of non-sustained ventricular tachycardia (NSVT) on the risk of thromboembolic event and clinical outcomes in patients without structural heart disease remains undetermined. This study aimed to evaluate the association between NSVT and clinical outcomes. METHODS: The study population of 5903 patients was culled from the "Registry of 24-hour ECG monitoring at Taipei Veterans General Hospital" (REMOTE database) between January 1, 2002 and December 31, 2004...
2016: PloS One
Min Soo Cho, Jun Kim, Ju Hyeon Kim, Minsu Kim, Ji Hyun Lee, You Mi Hwang, Uk Jo, Gi-Byoung Nam, Kee-Joon Choi, You-Ho Kim
Persistent atrial fibrillation (PeAF) predictors after dual-chamber pacemaker (PM) implantation remain unclear. We sought to determine these predictors and establish an integrated scoring model. Data were retrospectively reviewed for 649 patients (63.8 ± 12.3 years, 48.6% male, mean CHA2DS2-VASC score 2.7 ± 2.0) undergoing dual-chamber PM implantation. PeAF was defined as documented AF on two consecutive electrocardiograms acquired ≥7 days apart. During a 7.1-year median follow-up (interquartile range 4...
2016: PloS One
Alexandra M Lesenskyj, Christina R Maxwell, Erol Veznedaroglu, Kenneth Liebman, Zakaria Hakma, Mandy J Binning
INTRODUCTION: Immediate treatment has been shown to decrease the recurrence of cerebrovascular accidents following transient ischemic attacks (TIA), prompting the use of a specialized neurologic emergency department (Neuro ED) to triage patients. Despite these findings, there is little evidence supporting the notion that hospital admission improves post-TIA outcomes. Through the lens of a Neuro ED, this retrospective chart review of TIA patients examines whether hospital admission improves 90-day outcomes...
September 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
S M O Peeters Weem, S T W van Haelst, H M den Ruijter, F L Moll, G J de Borst
INTRODUCTION: Dual antiplatelet therapy (DAPT) has mainly replaced mono antiplatelet therapy (MAPT) and is recommended after arterial endovascular revascularization. The aim of this meta-analysis was to summarize the available evidence for DAPT after endovascular revascularization throughout the arterial system. METHODS: A systematic search was performed in Medline, Embase, and the Cochrane Register. Two reviewers independently performed data extraction and quality assessment using the Cochrane Collaboration risk of bias assessment tool...
August 2016: European Journal of Vascular and Endovascular Surgery
Mani Arsalan, Robert L Smith, John J Squiers, Alex Wang, J Michael DiMaio, Michael J Mack
Papillary fibroelastomas of the mitral chordae tendineae are rare, primary benign tumors. They are either incidentally diagnosed during echocardiography or discovered after transient ischemic attack, stroke, or myocardial infarction. Removal of papillary fibroelastomas should be considered, given the increased risk for embolization causing cerebrovascular accident or mortality in patients with echocardiographic evidence of papillary fibroelastoma not undergoing surgical procedures. Although fibroelastoma removal can be performed in most cases without disrupting mitral valve competency, sternotomy and minithoracotomy are the typical approaches for excision...
June 2016: Annals of Thoracic Surgery
Anahita Dua, Michael Romanelli, Gilbert R Upchurch, James Pan, Douglas Hood, Kim J Hodgson, Sapan S Desai
BACKGROUND: A variety of patient factors are known to adversely impact outcomes after carotid endarterectomy (CEA) or carotid artery stenting (CAS). However, their specific impact on complications and mortality and how they differ between CEA and CAS is unknown. The purpose of this study is to identify patient and hospital factors that adversely impact outcomes. METHODS: Patients who underwent CEA or CAS between 1998 and 2012 (N = 1,756,445) were identified using the Agency for Healthcare Research and Quality National Inpatient Sample and State Ambulatory Services Databases...
September 2016: Journal of Vascular Surgery
Ibrahim Marai, Mahmoud Suleiman, Miry Blich, Jonathan Lessick, Sobhi Abadi, Monther Boulos
AIM: To investigate the impact of using computed tomography (CT) and contact force (CF) technology on recurrence of atrial tachyarrhythmia after atrial fibrillation (AF) ablation. METHODS: This non-randomized study included 2 groups of patients. All patients had symptomatic recurrent paroxysmal or persistent AF and were treated with at least 1 anti arrhythmic medication or intolerant to medication. The first group included 33 patients who underwent circumferential pulmonary veins isolation (PVI) for AF during 2012 and 2013 guided by CT image integration (Cartomerge, Biosense Webster, Diamond Bar, CA, United States) of left atrium and pulmonary veins into an electroanatomic mapping (EAM) system (CT group) using standard irrigated radiofrequency catheter (ThermoCool, Carto, Biosense Webster, Diamond Bar, CA, United States) or irrigated catheter with integrated CF sensor (Smart Touch, Carto, Biosense Webster, Diamond Bar, CA, United States)...
April 26, 2016: World Journal of Cardiology
Yu Xia, David Stern, Patricia Friedmann, Daniel Goldstein
BACKGROUND: Atrial fibrillation (AF) is a well-established risk factor for thromboembolic (TE) complications. AF is frequently found in patients with advanced heart failure, including patients undergoing left ventricular assist device (LVAD) implantation. However, reports on whether preoperative AF increases the risk of TE events after LVAD implantation are scarce and limited to single-center or 2-center studies. We sought to evaluate the association of preoperative AF with TE events and patient survival using the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS)...
July 2016: Journal of Heart and Lung Transplantation
Michael Kim, Mehrdad Niroumandpour, Brian Poustinchian
Sclerotherapy is an increasingly popular treatment modality for patients with chronic venous insufficiency and varicose veins. Potential complications of foam sclerotherapy include cerebrovascular accidents and transient ischemic attacks (TIAs). We report the case of a 55-year-old woman who had a TIA shortly after undergoing foam sclerotherapy. She had presented for treatment with no confirmed risk factors for microemboli formation or thrombus. After the procedure, however, she had transient visual loss, dysarthria, confusion, and frontal headache, which resolved within 30 minutes of onset...
May 1, 2016: Journal of the American Osteopathic Association
Abha G Singh, Cynthia S Crowson, Siddharth Singh, Mark Denis P Davis, Hilal Maradit-Kremers, Eric L Matteson, Vaidehi R Chowdhary
OBJECTIVE: It is unclear whether isolated cutaneous lupus erythematosus (CLE) modifies cardiovascular risk. We estimated the cumulative incidence and mortality of cardiovascular diseases in a population-based CLE cohort, and compared the risk with a matched non-CLE cohort. METHODS: All incident cases of CLE in Olmsted County, Minnesota between 1965-2005 were followed until December 2013. Cumulative incidence of cerebrovascular accidents (CVA, including stroke, transient ischemic attack), ischemic heart disease (IHD, including coronary artery disease, myocardial infarction, angina), heart failure, and peripheral arterial disease was derived and compared to an age-, sex- and calendar-year-matched non-CLE cohort using Cox models...
March 25, 2016: Arthritis Care & Research
Romain Didier, Michael A Gaglia, Edward Koifman, Sarkis Kiramijyan, Smita I Negi, Al Fazir Omar, Jiaxing Gai, Rebecca Torguson, Augusto D Pichard, Ron Waksman
BACKGROUND: Cerebrovascular accident (CVA) and transient ischemic attack (TIA) related to percutaneous coronary intervention (PCI) are relatively rare complications, but they are associated with high morbidity and mortality. Given the evolution of both CVA risk and PCI techniques over time, this study was conducted to evaluate trends in CVA and TIA associated with PCI and to identify variables associated with neurologic events. METHODS: Consecutive patients undergoing PCI at the Washington Hospital Center between January 2002 and June 2015 were included...
February 2016: American Heart Journal
Dorien M Zelle, Eva Corpeleijn, Gerald Klaassen, Elise Schutte, Gerjan Navis, Stephan J L Bakker
BACKGROUND: Physical activity (PA) and exercise are commonly used as preventive measures for cardiovascular disease in the general population, and could be effective in the management of post-transplantation cardiovascular risk. PA levels are low after renal transplantation and very few renal transplant recipients (RTR) meet the PA guidelines. Identification of barriers to regular PA is important to identify targets for intervention to improve PA levels after renal transplantation. We investigated fear of movement and physical self-efficacy as barriers to PA in RTR...
2016: PloS One
Lena Innala, Clara Sjöberg, Bozena Möller, Lotta Ljung, Torgny Smedby, Anna Södergren, Staffan Magnusson, Solbritt Rantapää-Dahlqvist, Solveig Wållberg-Jonsson
BACKGROUND: Patients with rheumatoid arthritis (RA) suffer from co-morbidities that contribute to a shortened lifespan. Inflammation is important for the development of cardiovascular disease, but little is known on its relationship with other co-morbidities. We investigated the role of inflammation for the development of new comorbidities in early RA. METHODS: Since 1995, all patients with early RA in Northern Sweden are included in a prospective study on co-morbidities, with a total of 950 patients being included...
2016: Arthritis Research & Therapy
Stephen J Nicholls, A Michael Lincoff, Philip J Barter, H Bryan Brewer, Keith A A Fox, C Michael Gibson, Christopher Grainger, Venugopal Menon, Gilles Montalescot, Daniel Rader, Alan R Tall, Ellen McErlean, Jeffrey Riesmeyer, Burkhard Vangerow, Giacomo Ruotolo, Govinda J Weerakkody, Steven E Nissen
BACKGROUND: Potent pharmacologic inhibition of cholesteryl ester transferase protein by the investigational agent evacetrapib increases high-density lipoprotein cholesterol by 54% to 129%, reduces low-density lipoprotein cholesterol by 14% to 36%, and enhances cellular cholesterol efflux capacity. The ACCELERATE trial examines whether the addition of evacetrapib to standard medical therapy reduces the risk of cardiovascular (CV) morbidity and mortality in patients with high-risk vascular disease...
December 2015: American Heart Journal
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