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https://www.readbyqxmd.com/read/29452780/gender-differences-in-the-association-of-cognitive-impairment-with-the-risk-of-hip-fracture-in-the-older-population
#1
Elena Lobo, Guillermo Marcos, Javier Santabárbara, Luis Lobo-Escolar, Helena Salvador-Rosés, Concepción De la Cámara, Raul Lopez-Anton, Patricia Gracia-García, Antonio Lobo-Escolar
OBJECTIVES: To test the hypothesis that differences by gender will be observed in the association of hip fracture risk with stages of cognitive impairment; and to explore the association between Petersen's "mild cognitive impairment" (MCI) and DSM-5 "mild neurocognitive disorder" (MND). STUDY DESIGN: A community sample of 4803 individuals aged 55+ years was assessed in a two-phase case-finding enquiry in Zaragoza, Spain, and was followed up for 16 years...
March 2018: Maturitas
https://www.readbyqxmd.com/read/29452573/the-effect-of-metformin-treatment-in-obese-insulin-resistant-patients-with-euthyroid-goiter
#2
Nicoleta Răcătăianu, Sorana Daniela Bolboacă, Adela-Viviana Sitar-Tăut, Smaranda Mârza, Daniela Moga, Ana Valea, Cristina Ghervan
Objective The study's objective was to evaluate the thyroid parameters in obese insulin-resistant patients with euthyroid diffuse or nodular goiter, following Metformin treatment. Patients and methods The study was experimental, open, and prospective. Fifty-three patients aged 18-68 were enrolled for two years. Obese insulin-resistant patients (cut-off Homeostasis-Model-Assessment of Insulin Resistance-HOMA-IR ≥ 2.5) with euthyroid nodular/diffuse goiter were included. Subjects with diabetes, hypo-/hyper-thyroidism, autoimmune thyroiditis, psychiatric disorders, liver or heart failure were excluded...
February 16, 2018: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29451943/dual-diagnosis-and-total-hip-arthroplasty
#3
Mitchell R Klement, Brian T Nickel, Abiram Bala, Colin T Penrose, Cynthia L Green, Samuel S Wellman, Michael P Bolognesi, Thorsten M Seyler
The co-occurrence of a mental illness and a substance abuse disorder (SUD) is common and has been referred to as a "dual diagnosis" (DD). Although studies have independently investigated mental illness alone and SUD alone, few have examined the effects of these entities combined on complications. A search of the Medicare database from 2005 to 2012 identified 2000 DD patients who underwent total hip arthroplasty (THA). They were compared with 86,976 patients with mental illness only and 590,689 controls (no mental illness or SUD)...
February 16, 2018: Orthopedics
https://www.readbyqxmd.com/read/29451141/associations-between-body-composition-indices-and-metabolic-disorders-in-chinese-adults-a-cross-sectional-observational-study
#4
Rong Zhang, Sheng-Yong Dong, Fei Wang, Cong Ma, Xiao-Lan Zhao, Qiang Zeng, Ao Fei
Background: Obesity induces dyslipidemia, hypertension, glucose intolerance, and inflammatory state, which results in atherogenic processes, diabetes, and cardiovascular disease. We usually use body composition indices, such as body mass index (BMI), body fat percentage (BFP), waist circumference-height ratio (WHtR), and waist-hip ratio (WHR) to reflect the obesity. The aim of this large population-based cross-sectional study was to investigate the associations between body composition indices and metabolic parameters in Chinese adults...
February 20, 2018: Chinese Medical Journal
https://www.readbyqxmd.com/read/29436758/perception-of-dental-students-on-risk-factors-of-musculoskeletal-disorders
#5
A C Botta, C D Presoto, D Wajngarten, J A D B Campos, P P N S Garcia
OBJECTIVE: To evaluate the validity and reliability of the Job Factors Questionnaire, and the influence of gender, academic level and pain/discomfort on dental students' perception regarding risk factors of musculoskeletal disorders. METHODS: One hundred forty-five dental students from Stony Brook School of Dental Medicine participated voluntarily in this study. The survey was organised in two sections: (i) Job Factors Questionnaire with 15 items that evaluated students' perceptions about job/study environmental risk factors and their potential contribution to musculoskeletal disorders...
February 13, 2018: European Journal of Dental Education: Official Journal of the Association for Dental Education in Europe
https://www.readbyqxmd.com/read/29435956/robot-assisted-body-weight-supported-treadmill-training-in-gait-impairment-in-multiple-sclerosis-patients-a-pilot-study
#6
Marek Łyp, Iwona Stanisławska, Bożena Witek, Ewelina Olszewska-Żaczek, Małgorzata Czarny-Działak, Ryszard Kaczor
This study deals with the use of a robot-assisted body-weight-supported treadmill training in multiple sclerosis (MS) patients with gait dysfunction. Twenty MS patients (10 men and 10 women) of the mean of 46.3 ± 8.5 years were assigned to a six-week-long training period with the use of robot-assisted treadmill training of increasing intensity of the Lokomat type. The outcome measure consisted of the difference in motion-dependent torque of lower extremity joint muscles after training compared with baseline before training...
February 13, 2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29435469/prevalence-and-impact-of-hip-arthroscopic-surgery-on-future-participation-in-elite-american-football-athletes
#7
Derrick M Knapik, Joe Sheehan, Shane J Nho, James E Voos, Michael J Salata
Background: Intra-articular injuries to the hip in elite athletes represent a source of significant pain and disability. Hip arthroscopic surgery has become the gold standard for the treatment of disorders involving the hip joint. Purpose: To examine the incidence of and abnormalities treated with hip arthroscopic surgery as well as the impact on future participation in American football athletes invited to the National Football League (NFL) Scouting Combine with a history of hip arthroscopic surgery...
February 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29432506/eating-habits-and-nutritional-status-of-patients-with-affective-disorders-and-schizophrenia
#8
Ewa Stefańska, Magdalena Lech, Agnieszka Wendołowicz, Beata Konarzewska, Napoleon Waszkiewicz, Lucyna Ostrowska
OBJECTIVES: The aim of the study was to assess the nutritional value of the food intake in the group of men and women suffering from recurrent affective disorders and schizophrenia, and also to determine the relation between selected nutritional parameters with anthropometric indices defining the nutritional status of the subjects. METHODS: 219 persons participated in the study (61 patients with recurrent depressive disorders, 60 patients with schizophrenia and 98 healthy volunteers)...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29419677/risk-of-major-comorbidities-among-workers-with-hemophilia-a-14-year-population-based-study
#9
Wei-Min Chu, Hsin-En Ho, Jiaan-Der Wang, Wei-Cheng Chan, Yi-Sheng Liou, Wen-Chao Ho, Sung-Yuan Hu, Yu-Tse Tsan
Multiple comorbidities, especially musculoskeletal dysfunction and cerebrovascular disease, remain barriers to normal social participation among persons with hemophilia (PWH). However, the relative health effects of such comorbidities on workers with hemophilia have seldom been explored. In this study, we investigated the incidence of comorbidities and their risk factors among workers with hemophilia.The study compared the incidence and risk factors of the major comorbidities of 411 workers with hemophilia enrolled in Taiwan's National Health Insurance Research Database between 1997 and 2010 with an age- and sex-matched general population...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29412382/thyroid-disorders-in-obese-patients-does-insulin-resistance-make-a-difference
#10
Nicoleta Răcătăianu, Nicoleta Leach, Cosmina Ioana Bondor, Smaranda Mârza, Daniela Moga, Ana Valea, Cristina Ghervan
OBJECTIVE: The aim of this study was to evaluate the association between insulin resistance and thyroid pathology in obese patients, and compare the results between insulin-resistant and noninsulin-resistant patients. SUBJECTS AND METHODS: Obese/nondiabetic patients, aged 18-70 years, attending the outpatient endocrinology service for 2 years were consecutively included. We evaluated the patients' fasting plasma glucose, insulin, homeostasis model assessment of insulin resistance index (HOMA-IR), thyroid-stimulating hormone (TSH), free thyroxine (FT4), antithyroperoxidase antibodies (TPO-Ab), antithyroglobulin antibodies (Tg-Ab), and thyroid ultrasound...
December 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29411069/the-utility-of-frax%C3%A2-in-predicting-bone-fractures-in-patients-with-chronic-kidney-disease-on-hemodialysis-a-two-year-prospective-multicenter-cohort-study
#11
J Przedlacki, J Buczyńska-Chyl, P Koźmiński, E Niemczyk, E Wojtaszek, E Gieglis, P Żebrowski, A Podgórzak, J Wściślak, M Wieliczko, J Matuszkiewicz-Rowińska
We assessed the FRAX® method in 718 hemodialyzed patients in estimating increased risk of bone major and hip fractures. Over two prospective years, statistical analysis showed that FRAX® enables a better assessment of bone major fracture risk in these patients than any of its components and other risk factors considered in the analysis. INTRODUCTION: Despite the generally increased risk of bone fractures among patients with end-stage renal disease, no prediction models for identifying individuals at particular risk have been developed to date...
February 6, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29409733/nutrition-and-bone-density-in-boys-with-autism-spectrum-disorder
#12
Ann M Neumeyer, Natalia Cano Sokoloff, Erin I McDonnell, Eric A Macklin, Christopher J McDougle, Tara M Holmes, Jane L Hubbard, Madhusmita Misra
BACKGROUND: Boys with autism spectrum disorder (ASD) have lower bone mineral density (BMD) than typically developing controls. Differences in diet and exercise may contribute to low BMD. OBJECTIVE: Our aim was to examine macro- and micronutrient intakes and self-reported physical activity in boys with ASD compared to TDC and the relationship of these variables with BMD. DESIGN/METHODS: We conducted a cross-sectional study of 49 boys (25 ASD, 24 typically developing controls) assessed for 3-day food records and physical activity records, and BMD of the whole body less head, hip, and spine using dual-energy x-ray absorptiometry...
February 3, 2018: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29402715/does-parkinson-disease-increase-the-risk-of-perioperative-complications-after-total-hip-arthroplasty-a-nationwide-database-study
#13
Jared M Newman, Nipun Sodhi, Sarah E Dalton, Anton Khlopas, Richard P Newman, Carlos A Higuera, Michael A Mont
BACKGROUND: Parkinson disease (PD) is the second most common neurodegenerative disorder in the United States, affecting over 1 million people. As part of the disease process, PD can cause poor bone quality and other musculoskeletal problems that can affect a patient's quality of life. With advances in treatment, PD patients can be more active and may be candidates for total hip arthroplasty (THA). However, there is a paucity of literature on the outcomes of THA in PD patients. Therefore, the purpose of this study was to evaluate the perioperative outcomes of PD patients who underwent THA...
January 16, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29402310/fnirs-based-neurorobotic-interface-for-gait-rehabilitation
#14
Rayyan Azam Khan, Noman Naseer, Nauman Khalid Qureshi, Farzan Majeed Noori, Hammad Nazeer, Muhammad Umer Khan
BACKGROUND: In this paper, a novel functional near-infrared spectroscopy (fNIRS)-based brain-computer interface (BCI) framework for control of prosthetic legs and rehabilitation of patients suffering from locomotive disorders is presented. METHODS: fNIRS signals are used to initiate and stop the gait cycle, while a nonlinear proportional derivative computed torque controller (PD-CTC) with gravity compensation is used to control the torques of hip and knee joints for minimization of position error...
February 5, 2018: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/29396206/estimating-transition-probability-of-different-states-of-type-2-diabetes-and-its-associated-factors-using-markov-model
#15
Mahsa Nazari, Saeed Hashemi Nazari, Farid Zayeri, Mehrzad Gholampour Dehaki, Alireza Akbarzadeh Baghban
AIMS: Type 2 diabetes is a chronic metabolic disorder and one of the most common non-contagious diseases which is on the rise all over the world. The present study aims to assess the trend of change in fasting blood sugar (FBS) and factors associated with the progression and regression of type 2 diabetes. Moreover, this study estimates transition intensities and transition probabilities among various states using the multi-state Markov model. METHODS: In this study Multi-Ethnic Study of Atherosclerosis (MESA) dataset, from a longitudinal study, was used...
January 30, 2018: Primary Care Diabetes
https://www.readbyqxmd.com/read/29389793/complications-in-patients-undergoing-spinal-fusion-after-tha
#16
Bassel G Diebo, George A Beyer, Preston W Grieco, Shian Liu, Louis M Day, Roby Abraham, Qais Naziri, Peter G Passias, Aditya V Maheshwari, Carl B Paulino
INTRODUCTION: Patients with lumbar spine and hip disorders may, during the course of their treatment, undergo spinal fusion and THA. There is disagreement among prior studies regarding whether patients who undergo THA and spinal fusion are at increased risk of THA dislocation and other hip-related complications. QUESTIONS / PURPOSES: Is short or long spinal fusion associated with an increased rate of postoperative complications in patients who underwent a prior THA? PATIENTS AND METHODS: A retrospective study of New York State's Department of Health database (SPARCS) was performed...
February 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29383486/focal-disorders-of-the-spine-with-compensatory-deformities-how-to-define-them
#17
REVIEW
Andrea Redaelli, Pedro Berjano, Max Aebi
PURPOSE: In this paper, the authors propose classifying the epiphenomenon of spinal deformity in two different categories: structural deformity, when the main driver of the observed deformity is a fixed and stiff alteration of the spinal segments, and compensatory deformity, which includes cases where the observed deformity is due to focal abnormalities. This last category comprises, but is not limited to, spinal stenosis, spondylolisthesis, disc herniation, infection or tumor, hip disease or neurological disease (such as Parkinson's disease)...
January 30, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29382694/sickness-absence-due-to-different-musculoskeletal-diagnoses-by-occupational-class-a-register-based-study-among-1-2-million-finnish-employees
#18
Johanna Pekkala, Ossi Rahkonen, Olli Pietiläinen, Eero Lahelma, Jenni Blomgren
OBJECTIVES: Those in lower occupational classes have an increased risk of sickness absence due to musculoskeletal diseases (MSDs), but studies examining the associations simultaneously across specified diagnostic groups within MSDs are lacking. We examined occupational class differences in the occurrence and length of long-term sickness absence due to different musculoskeletal diagnoses. METHODS: A 70% random sample of employed Finns aged 25-64 years old at the end of 2013 was linked to data on sickness absence of over 10 working days obtained from The Social Insurance Institution of Finland and occupational class from Statistics Finland...
January 30, 2018: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/29373805/systematic-review-and-meta-analysis-of-outcomes-after-hip-arthroscopy-in-femoroacetabular-impingement
#19
Anas A Minkara, Robert W Westermann, James Rosneck, T Sean Lynch
BACKGROUND: Femoroacetabular impingement (FAI) has become a more commonly recognized cause of limited hip range of motion and hip pain among young adults and athletes. Hip arthroscopy is recommended for the surgical treatment of this disorder, unless specific contraindications exist. Despite the increasing rate of published studies in this area, there remains no aggregate data for outcomes after this approach. PURPOSE: To evaluate risk factors and outcomes after arthroscopic management of FAI, including return to play, revision rate, surgical and nonsurgical complications, change in α-angle, intraoperative bone resection, and patient-reported outcomes...
January 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29371932/identification-of-novel-genes-in-aging-osteoblasts-using-next-generation-sequencing-and-bioinformatics
#20
Yi-Jen Chen, Wei-An Chang, Ming-Shyan Huang, Chia-Hsin Chen, Kuan-Yuan Wang, Ya-Ling Hsu, Po-Lin Kuo
During the aging process, impaired osteoblastic function is one key factor of imbalanced bone formation and age-related bone loss. The aim of this study is to explore the differentially expressed genes in normal and aged osteoblasts and to identify genes potentially involved in age-related alteration in bone physiology. Based on next generation sequencing and bioinformatics analysis, 12 differentially expressed microRNAs and 22 differentially expressed genes were identified. Up-regulation of miR-204-5p was validated in an array of osteoporotic hip fracture in the Gene Expression Omnibus database (GSE74209)...
December 26, 2017: Oncotarget
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