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https://www.readbyqxmd.com/read/28544532/association-between-osteoarthritis-and-mental-health-in-a-korean-population-a-nationwide-study
#1
Jae Hyun Jung, Hongdeok Seok, Jae-Hoon Kim, Gwan Gyu Song, Sung Jae Choi
AIM: Osteoarthritis (OA) is a chronic disease and has become a major health problem in recent years. OA causes chronic pain and disability and can induce mental disorders such as stress perception, depression and suicidal ideation. We investigated the incidence of perceived stress, depressed mood and suicidal ideation in OA patients, using the 2010-2012 Korea National Health and Nutrition Examination Survey (KNHANES). METHOD: A total of 8271 participants were included (3580 male and 4691 female)...
May 25, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28542276/effect-of-combined-actions-of-hip-adduction-abduction-on-the-force-generation-and-maintenance-of-pelvic-floor-muscles-in-healthy-women
#2
Amanda C Amorim, Licia P Cacciari, Anice C Passaro, Simone R B Silveira, Cesar F Amorim, Jefferson F Loss, Isabel C N Sacco
Pelvic floor muscle (PFM) force and coordination are related to urinary incontinence severity and to sexual satisfaction. Health professionals frequently combine classic PFM exercises with hip adduction/abduction contraction to treat these disorders, but the real benefits of this practice are still unknown. Based on a theoretical anatomy approach whereby the levator ani muscle is inserted into the obturator internus myofascia and in which force generated by hip movements should increase the contraction quality of PFMs, our aim was to investigate the effects of isometric hip adduction and abduction on PFM force generation...
2017: PloS One
https://www.readbyqxmd.com/read/28536889/the-phenotype-of-patients-with-a-recent-fracture-a-literature-survey-of-the-fracture-liaison-service
#3
REVIEW
Lisanne Vranken, Caroline E Wyers, Joop P W van den Bergh, Piet P M M Geusens
The aetiology of fractures in patients aged 50 years and older is multifactorial, and includes bone- and fall-related risks. The Fracture Liaison Service (FLS) is recommended to identify patients with a recent fracture and to evaluate their subsequent fracture risk, in order to take measures to decrease the risk of subsequent fractures in patients with a high risk phenotype. A literature survey was conducted to describe components of the bone- and fall-related phenotype of patients attending the FLS. Components of the patient phenotype at the FLS have been reported in 33 studies...
May 24, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28529656/imaging-modalities-in-patients-with-slipped-capital-femoral-epiphysis
#4
T Hesper, C Zilkens, B Bittersohl, R Krauspe
BACKGROUND: Slipped capital femoral epiphysis (SCFE) is a frequent disorder of the adolescent hip, which may lead to avascular necrosis (AVN) of the femoral head, chondrolysis and early osteoarthritis due to the post-slip deformity of the proximal femur. To warrant the best possible outcome for the affected (and contralateral) hip, early diagnosis and proper treatment are needed. METHODS: A review of the literature was undertaken to identify today's role of available imaging modalities in the management of SCFE...
April 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28528779/atypical-articular-presentations-in-indian-children-with-rheumatic-fever
#5
Euden Bhutia, Dinesh Kumar, Mohan Kundal, Sunil Kishore, Atul Juneja
BACKGROUND: The objective of the study was to describe the clinical characteristics of atypical articular presentations during the initial outbreak and recurrence in patients with acute rheumatic fever (ARF) in the paediatric age group. METHODS: This was a retrospective, observational study conducted between January 2012 and December 2014 on all suspected cases of acute rheumatic fever (ARF) fulfilling either WHO 2004 or Australian guidelines with atypical articular manifestations ie, presence of at least one of the following features: duration of symptoms more than three weeks; monoarthritis/arthralgia; involvement of small joints of hand and feet and/or cervical spine and/or hip joint; and, not responding to salicylates in one week...
April 24, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28513428/slipped-capital-femoral-epiphysis-a-review-of-management-in-the-hip-impingement-era
#6
Mahmoud A Mahran, Mostafa M Baraka, Hany M Hefny
Slipped capital femoral epiphysis (SCFE) remains the most common adolescent hip disorder. Most cases present with stable slips, and in situ fixation is the most commonly adopted treatment worldwide. The introduction of the concept of femoroacetabular impingement and subsequent studies have revealed SCFE-related hip impingement to be a significant pre-arthritic condition, and the previously suggested remodeling of the proximal femur after in situ fixation has been called into question. Complex proximal femoral osteotomies and more recently intra-articular procedures via surgical hip dislocation have been employed...
2017: SICOT-J
https://www.readbyqxmd.com/read/28511457/leptin-as-a-predictive-marker-in-unexplained-infertility-in-north-indian-population
#7
Pratibha Kumari, S P Jaiswar, Pushplata Shankhwar, Sujata Deo, Kalim Ahmad, Bushra Iqbal, A A Mahdi
INTRODUCTION: According to WHO, the primary infertility in India is about 3.9% (age-standardized to 25-49 year) and 16.8% (age-standardized to 15-49 year), using the "age but no birth" definition. Several factors which affect fertility include low sperm production in men, poor egg quality and blocked fallopian tubes in women and also hormonal imbalances. Leptin plays a critical role in women's reproduction and neuroendocrine health. It is used for treating exercise-induced bone loss, eating disorders and infertility...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28510050/a-review-of-multi-domain-and-flexible-molecular-chaperones-studies-by-small-angle-x-ray-scattering
#8
REVIEW
Júlio C Borges, Thiago V Seraphim, Paulo R Dores-Silva, Leandro R S Barbosa
Intrinsic flexibility is closely related to protein function, and a plethora of important regulatory proteins have been found to be flexible, multi-domain or even intrinsically disordered. On the one hand, understanding such systems depends on how these proteins behave in solution. On the other, small-angle X-ray scattering (SAXS) is a technique that fulfills the requirements to study protein structure and dynamics relatively quickly with few experimental limitations. Molecular chaperones from Hsp70 and Hsp90 families are multi-domain proteins containing flexible and/or disordered regions that play central roles in cellular proteostasis...
June 2016: Biophysical Reviews
https://www.readbyqxmd.com/read/28507967/surgery-of-a-rare-case-of-multiple-synovial-osteochondromatosis-of-the-hip-joint
#9
Yi Min Zhang, Xiaoguang Liu
INTRODUCTION: Primary synovial osteochondromatosis of the hip is a benign disorder, which is not frequently seen clinically. The characteristic of this disease is proliferation of synovium and formation of loose bodies inside the joint. It is known that only the loose bodies derived from synovium were called synovial osteochondromatosis. Although it can take place in any joint, the knee is most commonly affected, involvement of the hip joint is relatively rare. We report a young man who has multiple synovial osteochondromatosis in his left hip...
November 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28497451/anterior-greater-trochanteric-muscle-pedicle-bone-grafting-a-viable-graft-option-adjunct-to-hip-osteotomy-or-fracture-surgery
#10
Noppachart Limpaphayom, Phatcharapa Osateerakun, Vajara Wilairatana, Pairatch Prasongchin
INTRODUCTION: The objectives were to evaluate a technique, outcome and complications following anterior greater trochanteric with gluteus medius muscle pedicle bone graft (AMG) procedure in the treatment of adolescent and active adult hip disorders. METHODS: 20 patients (20 hips) with a mean age of 22.7 ± 15.6 (range 10.0-63.5) years who had undergone AMG and been followed up more than 12 months postoperative were retrospectively enrolled in our study. The AMG procedure was performed in conjunction with subcapital osteotomy for slipped capital femoral epiphysis in 12 and open reduction for fracture/dislocation in 8 hips...
May 8, 2017: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/28493277/bone-mineral-density-in-complete-androgen-insensitivity-syndrome-and-the-timing-of-gonadectomy
#11
Thomas F J King, Winnie Z M Wat, Sarah M Creighton, Gerard S Conway
OBJECTIVE: Low bone mineral density (BMD) has been reported in complete androgen insensitivity syndrome (CAIS), but the impact of timing of gonadectomy is not known. We aimed to assess the relationship between age of gonadectomy and BMD in women with CAIS. DESIGN: Retrospective analysis of pre- and post-gonadectomy parameters in women with CAIS attending an adult Disorders of Sex Development (DSD) clinic in a tertiary centre. PATIENTS: One hundred and thirteen women with CAIS...
May 10, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28489131/incidence-of-delirium-in-postoperative-patients-treated-with-total-knee-and-hip-arthroplasty
#12
Felipe de Santana Bosmak, Patrick Teller Gibim, Sandra Guimarães, Adriano Luiz Ammirati
Introduction: Delirium is a common disorder that can potentiate mortality and comorbidity rates of patients hospitalized in intensive care units. Patients undergoing major orthopedic surgeries, such as knee and hip arthroplasty, are particularly vulnerable as they often have multiple risk factors for this disorder. Method: Descriptive study of the incidence of delirium in patients treated with total knee and hip arthroplasty, given the advanced age and comorbidities in this population...
March 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28488727/differences-in-sodium-fluoride-18-uptake-in-the-normal-skeleton-depending-on-the-location-and-characteristics-of-the-bone
#13
Shintaro Nawata, Tomohiro Kaneta, Matsuyoshi Ogawa, Yoshinobu Ishiwata, Naomi Kobayashi, Ayako Shishikura-Hino, Keisuke Yoshida, Yutaka Inaba, Tomoyuki Saito, Tomio Inoue
AIM: The aim of this study was to evaluate the normal distribution of sodium fluoride-18 (NaF-18) and to clarify the differences in uptake according to location and the type of the bone using positron emission tomography (PET) / computed tomography (CT). METHODS: We retrospectively reviewed NaF-18 PET/CT images from 30 patients with hip joint disorders. PET/CT scans were performed 40 min after injection of approximately 185 MBq of NaF-18. To evaluate the relationship between the distribution of NaF-18 uptake and bone density, we compared the maximum standardised uptake values (SUVmax) on PET and the Hounsfield Units (HUs) on CT of the lumbar vertebra, ilium, and proximal and distal femurs...
May 10, 2017: Nuklearmedizin. Nuclear Medicine
https://www.readbyqxmd.com/read/28487621/effect-of-drop-foot-on-spatiotemporal-kinematic-and-kinetic-parameters-during-gait
#14
Ida Wiszomirska, Michalina Błażkiewicz, Katarzyna Kaczmarczyk, Grażyna Brzuszkiewicz-Kuźmicka, Andrzej Wit
Background. The complexity of the structure and function of a living body can be affected by disorders and can cause various dysfunctions. Objective. The aim of this study was to determine compensatory mechanisms in subjects with drop foot during gait. Methods. The study evaluated 10 subjects with drop foot (DF) whose results were compared to a group of 10 healthy controls (C). Spatiotemporal, kinematic, and kinetic parameters during the gait cycle were collected using Vicon system synchronized with Kistler platforms...
2017: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/28479005/-risk-of-developmental-dysplasia-of-the-hip-in-patients-subjected-to-the-external-cephalic-version
#15
Nerea Sarmiento Carrera, Eva González Colmenero, José Luis Vázquez Castelo, Ana Concheiro Guisán, Emilio Couceiro Naveira, José Ramón Fernández Lorenzo
INTRODUCTION: Developmental dysplasia of the hip (DDH) refers to the spectrum of abnormalities of maturation and development of the hip. Breech presentation is associated with DDH. This risk factor can be modified by external cephalic version (ECV). The aim of this study is to evaluate the incidence of DDH in patients who successfully underwent ECV, as well as to evaluate need for these children (breech for a period during gestation) to be included in the DDH screening protocol. MATERIAL AND METHODS: A prospective cohort study was conducted in the Hospital Universitario de Vigo from January 1, 2015 to December 31, 2015...
May 3, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/28473755/the-combination-of-long-term-ketamine-and-extinction-training-contributes-to-fear-erasure-by-bdnf-methylation
#16
Ling-Sha Ju, Jiao-Jiao Yang, Lei Lei, Jiang-Yan Xia, Dan Luo, Mu-Huo Ji, Anatoly E Martynyuk, Jian-Jun Yang
A combination of antidepressant drugs and psychotherapy exhibits more promising efficacy in treating fear disorders than either treatment alone, but underlying mechanisms of such treatments remain largely unknown. Here we investigated the role of DNA methylation of the brain-derived neurotrophic factor (Bdnf) gene in the therapeutic effects of ketamine in combination with extinction training in a mouse model of post-traumatic stress disorder (PTSD) induced by inescapable electric foot shocks (IFS). Male mice received ketamine for 22 consecutive days starting 1 h after the IFS (long-term ketamine treatment) or 2 h prior to the extinction training on days 15 and 16 after the IFS (short-term ketamine treatment)...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28472303/the-effect-of-whole-body-vibration-training-on-bone-and-muscle-function-in-children-with-osteogenesis-imperfecta
#17
Wolfgang Högler, Janis Scott, Nick Bishop, Paul Arundel, Peter Nightingale, M Zulf Mughal, Raja Padidela, Nick Shaw, Nicola Crabtree
Context: Osteogenesis imperfecta (OI) is a bone fragility disorder associated with reduced muscle size, dynamic muscle function and mobility. Objective: To assess the effect of whole body vibration (WBV) training on bone density and geometry, muscle size and function, mobility, and balance in children with OI. Design: Randomised controlled pilot trial. Setting: Tertiary paediatric research centre. Participants: Twenty-four children (5-16 years) with OI types 1,4 and limited mobility (CHAQ score ≥0...
May 3, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28469972/a-wolf-in-sheep-s-clothing-an-alien-leg-in-corticobasal-syndrome
#18
Diana Angelika Olszewska, Allan McCarthy, Brian Murray, Brian Magennis, Sean Connolly, Tim Lynch
BACKGROUND: Alien limb phenomenon occurs in 50-60% of patients with corticobasal syndrome (CBS) and usually presents with an "alien hand" phenomenon. The "alien foot" presentation is rarer and may be misdiagnosed, as foot involvement can lead to erroneous localization of the clinical problem to the knee, hip, or back. Subsequently misdiagnoses such as myelopathy, radiculopathy, functional disorder, stiff leg syndrome, neuromyotonia, and painful leg moving toes syndrome may occur. CASE REPORT: We describe two patients with alien foot symptoms that resulted in multiple opinions from different specialists, multiple diagnostic and therapeutic procedures, and delayed diagnosis...
2017: Tremor and Other Hyperkinetic Movements
https://www.readbyqxmd.com/read/28466612/exploring-the-association-between-legg-calv%C3%A3-perthes-disease-and-attention-deficit-hyperactivity-disorder-in-children
#19
Julia Berman, Adi Aran, Tamar Berenstein-Weyel, Ehud Lebel
BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is an idiopathic hip osteonecrosis prevalent in children < age 15 years. The etiology remains incompletely understood, partly because of multiple potential environmental risk factors and partly because of lack of genetic markers. It has been hypothesized that hyperactivity may induce mechanical stress and/or vascular damage at a fragile joint. OBJECTIVES: To assess children with LCPD for markers of attention deficit hyperactivity disorder (ADHD) relative to their unaffected comparably aged siblings to exclude the contribution of hyperactive behavior versus environmental and/or genetic factors in LCPD...
November 2016: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/28465284/development-of-diabetes-does-not-alter-behavioral-and-molecular-circadian-rhythms-in-a-transgenic-rat-model-of-type-2-diabetes-mellitus
#20
Jingyi Qian, Anthony P Thomas, Analyne M Schroeder, Kuntol Rakshit, Christopher S Colwell, Aleksey V Matveyenko
Metabolic state and circadian clock function exhibit complex bidirectional relationship. Circadian disruption increases propensity for metabolic dysfunction, whereas common metabolic disorders such as obesity and Type 2 diabetes (T2DM) are associated with impaired circadian rhythms. Specifically, alterations in glucose availability and glucose metabolism have been shown to modulate clock gene expression and function in vitro; however to date it is unknown whether development of diabetes imparts deleterious effects on the suprachiasmatic nucleus (SCN) circadian clock and SCN-driven outputs in vivo...
May 2, 2017: American Journal of Physiology. Endocrinology and Metabolism
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