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https://www.readbyqxmd.com/read/27924492/progression-of-gait-ataxia-in-patients-with-degenerative-cerebellar-disorders-a-4-year-follow-up-study
#1
Mariano Serrao, Giorgia Chini, Carlo Casali, Carmela Conte, Martina Rinaldi, Alberto Ranavolo, Christian Marcotulli, Luca Leonardi, Gaia Fragiotta, Fabiano Bini, Gianluca Coppola, Francesco Pierelli
In the present study, the progression of gait impairment in a group of patients with primary degenerative cerebellar ataxias was observed over a period of 4 years. A total of 30 patients underwent an initial gait analysis study, and thereafter only 12 were evaluated because they completed the 2- and 4-year follow-up evaluations. Time-distance parameters, trunk and joint range of motion (RoM), and variability parameters (e.g., coefficients of variation) were measured at the baseline and at each follow-up evaluation...
December 6, 2016: Cerebellum
https://www.readbyqxmd.com/read/27924381/dual-energy-x-ray-absorptiometry-and-fracture-prediction-in-patients-with-spinal-cord-injuries-and-disorders
#2
L Abderhalden, F M Weaver, M Bethel, H Demirtas, S Burns, J Svircev, H Hoenig, K Lyles, S Miskevics, L D Carbone
: Low T-scores at the hip predict incident fractures in persons with a SCI. INTRODUCTION: Persons with a spinal cord injury (SCI) have substantial morbidity and mortality following osteoporotic fractures. The objective of this study was to determine whether dual-energy X-ray absorptiometry (DXA) measurements predict osteoporotic fractures in this population. METHODS: A retrospective historical analysis that includes patients (n = 552) with a SCI of at least 2 years duration who had a DXA performed and were in the VA Spinal Cord Disorders Registry from fiscal year (FY) 2002-2012 was performed...
December 6, 2016: Osteoporosis International
https://www.readbyqxmd.com/read/27919237/a-novel-ano3-variant-identified-in-a-53-year-old-woman-presenting-with-hyperkinetic-dysarthria-blepharospasm-hyperkinesias-and-complex-motor%C3%A2-tics
#3
Patrick R Blackburn, Michael T Zimmermann, Jennifer M Gass, Kimberly G Harris, Margot A Cousin, Nicole J Boczek, Owen A Ross, Eric W Klee, Paul W Brazis, Jay A Van Gerpen, Paldeep S Atwal
BACKGROUND: Cervical dystonias have a variable presentation and underlying etiology, but collectively represent the most common form of focal dystonia. There are a number of known genetic forms of dystonia (DYT1-27); however the heterogeneity of disease presentation does not always make it easy to categorize the disease by phenotype-genotype comparison. CASE PRESENTATION: In this report, we describe a 53-year-old female who presented initially with hand tremor following a total hip arthroplasty...
December 5, 2016: BMC Medical Genetics
https://www.readbyqxmd.com/read/27919200/bony-ankylosis-of-the-facet-joint-of-the-cervical-spine-in-rheumatoid-arthritis-its-characteristics-and-relationship-to-the-clinical-findings
#4
Haku Iizuka, Yoichi Iizuka, Koichi Okamura, Yukio Yonemoto, Tokue Mieda, Kenji Takagishi
OBJECTIVES: The purpose of this study was to clarify the characteristics of bony ankylosis of the facet joint of the cervical spine in RA patients who required cervical spine surgery, and its relationship to the clinical findings. METHODS: Eighty consecutive RA patients with cervical spine disorder who received initial surgery were reviewed. The occurrence of bony ankylosis of the facet joint of the cervical spine was investigated using computed tomography (CT) before surgery...
December 6, 2016: Modern Rheumatology
https://www.readbyqxmd.com/read/27918081/st1926-attenuates-steroid-induced-osteoporosis-in-rats-by-inhibiting-inflammation-response
#5
Hong-Xing Zhao, Yuan-Xia Huang, Jin-Gang Tao
Steroid, also known as glucocorticoid, induced osteonecrosis of the femoral head in young adults, which has been a challenging disorder for the frequent incidence of collapse of femoral head, leading to dysfunction of hip joint and impairing life quality of human. Bioavailable and less toxic synthetic retinoids, such as the atypical adamantyl retinoid ST1926, have been developed and investigated in clinical trials for many diseases. Serum lipid-related indicators were assessed to elucidate the role of ST1926 in regulating lipid metabolism...
December 5, 2016: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/27913128/the-impact-of-solid-organ-transplant-history-on-inpatient-complications-mortality-length-of-stay-and-cost-for-primary-total-hip-arthroplasty-admissions-in-the-united-states
#6
Suparna M Navale, Caleb R Szubski, Alison K Klika, Nicholas K Schiltz, Pratik P Desai, Wael K Barsoum
BACKGROUND: As the prevalence of and life expectancy after solid organ transplantation increases, some of these patients will require total hip arthroplasty (THA). Immunosuppressive therapy, metabolic disorders, and post-transplant medications may place transplant patients at higher risk of adverse events following surgery. The objective of this study was to compare inpatient complications, mortality, length of stay (LOS), and costs for THA patients with and without solid organ transplant history...
November 10, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27908845/design-response-rates-and-population-characteristics-of-a-cross-sectional-study-in-zanzibar-tanzania
#7
Maria Adam Nyangasa, Soerge Kelm, Mohammed Ali Sheikh, Antje Hebestreit
BACKGROUND: Data on nutritional status and correlates of noncommunicable diseases are scarce for resource-poor settings in sub-Saharan countries. With the scope of a project, "Access to Food and Nutrition Status of the Zanzibari Population," data for investigating public health questions were collected using proven measurement and laboratory standards. OBJECTIVE: The present study aims at providing a descriptive overview of recruitment approaches, standardization, quality control measures, and data collection, with special attention to the design, responses, and participant characteristics of the overall project...
December 1, 2016: JMIR Research Protocols
https://www.readbyqxmd.com/read/27908278/comparison-of-predictors-of-hip-fracture-and-mortality-after-hip-fracture-in-community-dwellers-with-and-without-alzheimer-s-disease-exposure-matched-cohort-study
#8
Anna-Maija Tolppanen, Heidi Taipale, Antti Tanskanen, Jari Tiihonen, Sirpa Hartikainen
BACKGROUND: Dementia, with Alzheimer's disease (AD) being the most common form, is a major hip fracture risk factor, but currently it is not known whether the same factors predict hip fracture among persons with and without dementia/AD. We compared the predictors of hip fracture and mortality after hip fracture in persons with and without AD. METHODS: An exposure-matched cohort of all community-dwellers of Finland who received a new clinically verified AD diagnosis in 2005-2011 and had no history of previous hip fracture (N = 67,072) and an age, sex, and region-matched cohort of persons without AD (N = 67,072)...
December 1, 2016: BMC Geriatrics
https://www.readbyqxmd.com/read/27906744/reliability-of-sagittal-spinopelvic-alignment-measurements-after-total-hip-arthroplasty
#9
Katri Pernaa, Matti Seppänen, Keijo Mäkelä, Mikhail Saltychev
STUDY DESIGN: This is a observational study. OBJECTIVE: To evaluate the reliability of measuring sagittal spinopelvic alignment after hip arthroplasty. SUMMARY OF BACKGROUND DATA: Pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT), and lumbar lordosis (LL) are widely used in planning the treatment of people with spinal and hip disorders. Previously, these measures have proved reliable when hip heads are intact. Thus far, it is not known whether they are also reliable after total hip replacement...
November 30, 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27904792/current-concepts-and-treatment-of-patellofemoral-compressive-issues
#10
Michael J Mullaney, Takumi Fukunaga
Patellofemoral disorders, commonly encountered in sports and orthopedic rehabilitation settings, may result from dysfunction in patellofemoral joint compression. Osseous and soft tissue factors, as well as the mechanical interaction of the two, contribute to increased patellofemoral compression and pain. Treatment of patellofemoral compressive issues is based on identification of contributory impairments. Use of reliable tests and measures is essential in detecting impairments in hip flexor, quadriceps, iliotibial band, hamstrings, and gastrocnemius flexibility, as well as in joint mobility, myofascial restrictions, and proximal muscle weakness...
December 2016: International Journal of Sports Physical Therapy
https://www.readbyqxmd.com/read/27903225/weight-bearing-joints-destruction-in-rheumatoid-arthritis
#11
Takashi Imagama, Atsunori Tokushige, Kazushige Seki, Toshihiko Taguchi
In many cases of rheumatoid arthritis (RA) joints of the upper extremities are affected. However, involvement of weight bearing joints of the lower extremities is strongly associated with a decreased activities of daily living ability such as gait disorder. Once the progression of weight bearing joint destruction occurs, lower extremity function will decrease even if RA disease activity is improved by pharmacotherapy. In this article, we investigated joint destruction-suppressing effects of pharmacotherapy on the hip and knee joints, as well as risk factors for joint destruction...
November 30, 2016: Current Rheumatology Reviews
https://www.readbyqxmd.com/read/27900190/prospective-12-month-functional-and-vocational-outcomes-of-hip-arthroscopy-for-femoroacetabular-impingement-as-part-of-an-evidence-based-hip-pain-rehabilitation-pathway-in-an-active-military-population
#12
A N Bennett, J Nixon, A Roberts, R Barker-Davies, R Villar, J M Houghton
BACKGROUND: Femoroacetabular impingement (FAI) is common with an estimated prevalence of 10-15% among young active individuals. The natural history of the disorder is progression to early osteoarthritis. Hip arthroscopy is recommended if conservative treatments fail; however, outcomes are unclear, particularly in highly active populations. AIM: To evaluate the functional and vocational outcome of hip arthroscopy, as part of an evidence-based rehabilitation hip pain pathway, for the treatment of FAI in an active military population...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27892801/stability-and-migration-across-femoral-varus-derotation-osteotomies-in-children-with-neuromuscular-disorders
#13
Peter Buxbom, Stig Sonne-Holm, Niels Ellitsgaard, Christian Wong
Background and purpose - Studies have indicated that one-third of children with cerebral palsy (CP) develop dislocation of the hip that needs surgical intervention. When hip dislocation occurs during childhood surgical treatment consists of tenotomies, femoral varus derotation osteotomy (VDRO), and acetabuloplasty. Relapse is observed in one-fifth of cases during adolescence. In this prospective cohort study, we performed a descriptive evaluation of translation and rotation across VDROs in children with neuromuscular disorders and syndromes by radiostereometric analysis (RSA)...
November 28, 2016: Acta Orthopaedica
https://www.readbyqxmd.com/read/27889923/normal-radiological-unossified-hip-joint-space-and-femoral-head-size-development-during-growth-in-675-children-and-adolescents
#14
Veronika Wegener, Gabriele Jorysz, Andreas Arnoldi, Sandra Utzschneider, Bernd Wegener, Volkmar Jansson, Bernhard Heimkes
Evaluation of hip joint space width during child growth is important to aid in the early diagnosis of hip pathology in children. We established reference values for hip joint space and femoral head size for each age. Hip joint space development during growth was retrospectively investigated medial and cranial in 1350 hip joints of children using standard anteroposterior supine plain pelvic radiographs. Maximum capital femoral epiphysis diameter and femoral radii were further more investigated. Hip joint space values show a slow decline during growth...
November 7, 2016: Clinical Anatomy
https://www.readbyqxmd.com/read/27887681/bone-accrual-in-males-with-autism-spectrum-disorder
#15
Ann M Neumeyer, Natalia Cano Sokoloff, Erin McDonnell, Eric A Macklin, Christopher J McDougle, Madhusmita Misra
OBJECTIVE: To test the hypothesis that bone accrual over a 4-year period is reduced in boys with autism spectrum disorder (ASD) compared with typically developing controls. STUDY DESIGN: Twenty-five boys with ASD and 24 controls were assessed for bone outcomes. Fourteen boys with ASD and 11 controls were assessed both at baseline and after 4 years. The mean subject age was 11.0 ± 1.6 years at study initiation and 14.9 ± 1.6 years at follow-up. Bone mineral density (BMD) was measured at the spine, hip, and whole body using dual-energy X-ray absorptiometry and normalized for age, race, and sex (BMD z-scores)...
November 22, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27881628/normative-reference-values-for-strength-and-flexibility-of-1-000-children-and-adults
#16
Marnee J McKay, Jennifer N Baldwin, Paulo Ferreira, Milena Simic, Natalie Vanicek, Joshua Burns
OBJECTIVE: To establish reference values for isometric strength of 12 muscle groups and flexibility of 13 joint movements in 1,000 children and adults and investigate the influence of demographic and anthropometric factors. METHODS: A standardized reliable protocol of hand-held and fixed dynamometry for isometric strength of ankle, knee, hip, elbow, and shoulder musculature as well as goniometry for flexibility of the ankle, knee, hip, elbow, shoulder, and cervical spine was performed in an observational study investigating 1,000 healthy male and female participants aged 3-101 years...
November 23, 2016: Neurology
https://www.readbyqxmd.com/read/27881118/electrolyte-disorders-and-aging-risk-factors-for-delirium-in-patients-undergoing-orthopedic-surgeries
#17
Li-Hong Wang, Dong-Juan Xu, Xian-Jiao Wei, Hao-Teng Chang, Guo-Hong Xu
BACKGROUND: At present, the exact mechanism of postoperative delirium has not been elucidated. The purpose of this study was to analyze the incidence of delirium in patients undergoing orthopedic surgeries and to explore possible related factors. METHODS: This is a retrospective study. We used 582 patients who had undergone orthopedic surgery between January 2011 and December 2014. The surgeries consisted of 155 cases of internal fixation for intertrochanteric fracture (IFIF), 128 cases of femoral head replacement (FHR), 169 cases of total hip arthroplasty (THA) and 130 cases of total knee arthroplasty (TKA)...
November 23, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27876489/morphologic-changes-and-outcomes-after-arthroscopic-acetabular-labral-repair-evaluated-using-postoperative-computed-tomography-arthrography
#18
Jun-Il Yoo, Yong-Chan Ha, Young-Kyun Lee, Guen-Young Lee, Moon-Jib Yoo, Kyung-Hoi Koo
PURPOSE: To investigate smaller sized labra after acetabular labral repair comparing preoperative and postoperative computed tomography arthrography (CTA) and to assess the correlation between the anatomic changes and clinical outcomes. METHODS: The design and protocol of this retrospective study were approved by the institutional review board of our hospital. The inclusion criteria included age older than 18 years and hip pain associated with mechanical symptoms...
November 19, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/27876030/long-term-outcomes-following-lower-extremity-press-fit-bone-anchored-prosthesis-surgery-a-5-year-longitudinal-study-protocol
#19
Ruud A Leijendekkers, J Bart Staal, Gerben van Hinte, Jan Paul Frölke, Hendrik van de Meent, Femke Atsma, Maria W G Nijhuis-van der Sanden, Thomas J Hoogeboom
BACKGROUND: Patients with lower extremity amputation frequently suffer from socket-related problems. This seriously limits prosthesis use, level of activity and health-related quality of life (HRQoL). An additional problem in patients with lower extremity amputation are asymmetries in gait kinematics possibly accounting for back pain. Bone-anchored prostheses (BAPs) are a possible solution for socket-related problems. Knowledge concerning the level of function, activity and HRQoL after surgery is limited...
November 22, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27869410/the-effect-of-strength-training-based-on-process-approach-intervention-on-balance-of-children-with-developmental-coordination-disorder
#20
Hasan Kordi, Mehdi Sohrabi, Alireza Saberi Kakhki, Seyed R Attarzadeh Hossini
INTRODUCTION: Balance is one of the main problems of children with developmental coordination disorder (DCD). According to process-oriented approach, besides strength training, neuromuscular adaptations can improve balance. OBJETIVE: To evaluate the effects of strength training on improving static and dynamic balance in DCD children. METHODS AND POPULATION: Children between 7 to 9 years old in Tehran participated in the study through randomized controlled trial design...
December 1, 2016: Archivos Argentinos de Pediatría
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