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https://www.readbyqxmd.com/read/28717153/proton-pump-inhibitors-and-the-risk-for-fracture-at-specific-sites-data-mining-of-the-fda-adverse-event-reporting-system
#1
Liwei Wang, Mei Li, Yuying Cao, Zhengqi Han, Xueju Wang, Elizabeth J Atkinson, Hongfang Liu, Shreyasee Amin
Proton pump inhibitors (PPIs) are widely used to treat gastric acid-related disorders. Concerns have been raised about potential fracture risk, especially at the hip, spine and wrist. However, fracture risk at other bone sites has not been as well studied. We investigated the association between PPIs and specific fracture sites using an aggregated knowledge-enhanced database, the Food and Drug Administration Adverse Event Reporting System Data Mining Set (AERS-DM). Proportional reporting ratio (PRR) was used to detect statistically significant associations (signals) between PPIs and fractures...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28712821/appropriate-anthropometric-indices-of-obesity-and-overweight-for-diagnosis-of-metabolic-syndrome-and-its-relationship-with-oxidative-stress
#2
Mehri Delvarianzadeh, Maryam Abbasian, Farideh Khosravi, Hossein Ebrahimi, Mohammad Hossein Ebrahimi, Mozhgan Fazli
AIMS: this study aimed to determine the most appropriate anthropometric indices for diagnosis of metabolic syndrome (MetS) and its relationship with oxidative stress markers. MATERIAL AND METHODS: This cross-sectional study was conducted in 2015 on 108 employees working in Shahroud University of Medical Sciences. Demographics, anthropometric indices (BMI: Body mass index; WC: Waist circumference, WHR: Waist hip ratio, WHtR: Waist-to-height Ratio), Mets: and Then oxidative stress markers (total antioxidant capacity; TAC, Malondialdehyde; MDA, serum superoxide dismutase; SOD, catalase; Cat) were measured...
July 8, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28712531/the-role-of-tryptophan-metabolism-and-food-craving-in-the-relationship-between-obesity-and-bipolar-disorder
#3
N Dalkner, M Platzer, S A Bengesser, A Birner, F T Fellendorf, R Queissner, A Painold, H Mangge, D Fuchs, B Reininghaus, H P Kapfhammer, S J Holasek, E Z Reininghaus
BACKGROUND & AIMS: Individuals with bipolar disorder (BD) have a significantly increased risk of obesity-related conditions. The imbalance between food intake and energy expenditure is assumed to be a major risk factor for obesity in BD. This study analyzed food craving in relation to anthropometric, metabolic, and neurobiological parameters in a well-characterized cohort of euthymic individuals with BD. METHODS: One-hundred-thirty-five patients completed the Food-Craving Inventory assessing four categories of food craving (fat, fast-food, sweets and carbohydrate craving)...
July 4, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28706820/basic-hip-arthroscopy-diagnostic-hip-arthroscopy
#4
Austin V Stone, Elizabeth A Howse, Sandeep Mannava, Brooke A Miller, Daniel Botros, Allston J Stubbs
Hip arthroscopy is increasing in popularity for the diagnosis and management of hip preservation. The basics of hip arthroscopy positioning, fluoroscopic assessment, and portal establishment are reviewed in the first 2 parts of this series. This article is the third installment in which we describe a systematic approach to performing a diagnostic hip arthroscopy. A mastery of diagnostic arthroscopy is necessary for surgeons treating hip disorders.
June 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/28705170/can-lokomat-therapy-with-children-and-adolescents-be-improved-an-adaptive-clinical-pilot-trial-comparing-guidance-force-path-control-and-freed
#5
Tabea Aurich-Schuler, Fabienne Grob, Hubertus J A van Hedel, Rob Labruyère
BACKGROUND: Robot-assisted gait therapy is increasingly being used in pediatric neurorehabilitation to complement conventional physical therapy. The robotic device applied in this study, the Lokomat (Hocoma AG, Switzerland), uses a position control mode (Guidance Force), where exact positions of the knee and hip joints throughout the gait cycle are stipulated. Such a mode has two disadvantages: Movement variability is restricted, and patients tend to walk passively. Kinematic variability and active participation, however, are crucial for motor learning...
July 14, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28702399/bilateral-simultaneous-neck-femur-fracture-following-domestic-fall-in-an-elderly-patient-a-rare-case-report
#6
Mayank Vijayvargiya, Vivek Shetty, Kiran Makwana, Nitesh Agarwal
Simultaneous bilateral neck femur fracture is a rare entity that has been associated with underlying bone disease, various metabolic diseases, high-energy trauma, and seizure disorders. Its occurrence following minimal trauma is very rare. This article presents the case of a 66-year-old female who sustained bilateral intracapsular fracture neck femur following a slip and fall at home. Single-stage bilateral cemented total hip replacement was done using a direct lateral approach with alternate right and left lateral positions...
May 2017: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/28700708/lower-extremity-emg-driven-modeling-of-walking-with-automated-adjustment-of-musculoskeletal-geometry
#7
Andrew J Meyer, Carolynn Patten, Benjamin J Fregly
Neuromusculoskeletal disorders affecting walking ability are often difficult to manage, in part due to limited understanding of how a patient's lower extremity muscle excitations contribute to the patient's lower extremity joint moments. To assist in the study of these disorders, researchers have developed electromyography (EMG) driven neuromusculoskeletal models utilizing scaled generic musculoskeletal geometry. While these models can predict individual muscle contributions to lower extremity joint moments during walking, the accuracy of the predictions can be hindered by errors in the scaled geometry...
2017: PloS One
https://www.readbyqxmd.com/read/28693117/joint-association-of-screen-time-and-physical-activity-with-anthropometric-measures-in-iranian-children-and-adolescents-the-weight-disorders-survey-of-the-caspian-iv-study
#8
Shirin Djalalinia, Mostafa Qorbani, Negar Rezaei, Ali Sheidaei, Armita Mahdavi-Gorabi, Amir Kasaeian, Mohammad Esmaeil Motlagh, Hamid Asayesh, Saeid Safiri, Roya Kelishadi
BACKGROUND: This study aims to assess the joint association of screen time (ST) and physical activity (PA) with anthropometric indices among Iranian children and adolescents. METHODS: In this national study, 23,183 school students, aged 6-18 years, were studied. By using a multi-stage cluster sampling method, they were selected from rural and urban areas of 30 provinces of Iran. ST and PA were assessed by self-administered validated questionnaires. Height, weight, hip and waist circumferences (WC) were measured according to standard protocols, and body mass index (BMI) was calculated...
June 23, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28692452/acetabular-protrusio-in-patients-with-osteogenesis-imperfecta-risk-factors-and-progression
#9
Junho Ahn, Erin Carter, Cathleen L Raggio, Daniel W Green
BACKGROUND: Osteogenesis imperfecta (OI) is a genetic disorder commonly associated with osteopenia, osteoporosis, bone fractures, bone deformities, and other clinical features. A frequent radiologic finding with OI is acetabular protrusio (AP). We hypothesized that AP develops in patients with OI over time. In addition, we hypothesized that AP also develops in patients with OI without radiographic evidence of AP on initial examination. METHODS: Medical records and radiographs of 55 patients (109 hips) diagnosed with OI evaluated at our institution were retrospectively reviewed...
July 7, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28692451/the-value-of-musculoskeletal-ultrasound-in-geriatric-care-and-rehabilitation
#10
Büşra Can, Murat Kara, Özgür Kara, Zekeriya Ülger, Walter Frontera, Levent Özçakar
The WHO reports that one of the major chronic conditions affecting the elderly worldwide is musculoskeletal disorders that are associated with long-term pain and disability. Considering the healthcare needs of the elderly (i.e. comprehensive, accessible, efficient) and the advantages of ultrasound (US) use (patient-friendly, convenient, cost-effective, and does not require exposure to radiation or magnetic fields), there seems to be a 'gap' in the actual clinical practice. In this paper, we aimed to highlight the potential value of US imaging in the management of the elderly with a wide spectrum of musculoskeletal conditions (degenerative/rheumatic joint diseases, falls/trauma, nursing care, peripheral nerve problems, sarcopenia, and interventions)...
July 7, 2017: International Journal of Rehabilitation Research. Revue Internationale de Recherches de Réadaptation
https://www.readbyqxmd.com/read/28688837/tendon-disorders-after-total-hip-arthroplasty-evaluation-and-management
#11
REVIEW
Brian M Capogna, Kartik Shenoy, Thomas Youm, Steven A Stuchin
BACKGROUND: Most patients who undergo total hip arthroplasty are very satisfied with their outcomes. However, there is a small subset of patients who have persistent pain after surgery. The etiology of pain after total hip arthroplasty varies widely; however, tendon disorders are a major cause of debilitating pain that often go unrecognized. METHODS: We performed a literature review to identify the most common tendon pathologies after total hip arthroplasty which include iliopsoas tendinitis, greater trochanteric pain syndrome, snapping hip syndrome, and abductor tendinopathy...
April 27, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28678628/indications-for-hip-arthroscopy
#12
James R Ross, Christopher M Larson, Asheesh Bedi
CONTEXT: Hip arthroscopy is gaining popularity within the field of orthopaedic surgery. The development and innovation of hip-specific arthroscopic instrumentation and improved techniques has resulted in improved access to the hip joint and ability to treat various hip pathologies. EVIDENCE ACQUISITION: Electronic databases, including PubMed and MEDLINE, were queried for articles relating to hip arthroscopy indications (1930-2017). STUDY DESIGN: Clinical review...
July 1, 2017: Sports Health
https://www.readbyqxmd.com/read/28677227/the-atypical-dopamine-receptor-agonist-skf-83959-enhances-hippocampal-and-prefrontal-cortical-neuronal-network-activity-in-a-rat-model-of-cognitive-dysfunction
#13
Melissa L Perreault, Theresa Fan, Tomek J Banasikowski, Anthony A Grace, Susan R George
Deficits in neuronal network synchrony in hippocampus and prefrontal cortex have been widely demonstrated in disorders of cognitive dysfunction, including schizophrenia and Alzheimer's disease. The atypical dopamine agonist SKF 83959 has been shown to increase brain-derived neurotrophic factor signaling and suppress activity of glycogen synthase kinase-3 in PFC, two processes important to learning and memory. The purpose of this study was to therefore evaluate the impact of SKF 83959 on oscillatory deficits in methylazoxymethanol acetate (MAM) rat model of schizophrenia...
July 5, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28676362/musculoskeletal-approach-to-pelvic-pain
#14
REVIEW
Kate E Temme, Jason Pan
Visceral and somatic causes of pelvic pain are often inter-related, and a musculoskeletal examination should always be considered for the successful diagnosis and treatment of pelvic pain. For the diverse etiologies of hip pain, there are many unique considerations for the diagnosis and treatment of these various disorders. Pelvic pain is often multidimensional due to the overlap between lumbo-hip-pelvic diagnoses and may require a multidisciplinary approach to evaluation and management.
August 2017: Physical Medicine and Rehabilitation Clinics of North America
https://www.readbyqxmd.com/read/28672741/joint-association-of-screen-time-and-physical-activity-with-anthropometric-measures-in-iranian-children-and-adolescents-the-weight-disorders-survey-of-the-caspian-iv-study
#15
Shirin Djalalinia, Mostafa Qorbani, Negar Rezaei, Ali Sheidaei, Armita Mahdavi-Gorabi, Amir Kasaeian, Mohammad Esmaeil Motlagh, Hamid Asayesh, Saeid Safiri, Roya Kelishadi
BACKGROUND: This study aims to assess the joint association of screen time (ST) and physical activity (PA) with anthropometric indices among Iranian children and adolescents. METHODS: In this national study, 23,183 school students, aged 6-18 years, were studied. By using a multi-stage cluster sampling method, they were selected from rural and urban areas of 30 provinces of Iran. ST and PA were assessed by self-administered validated questionnaires. Height, weight, hip and waist circumferences (WC) were measured according to standard protocols, and body mass index (BMI) was calculated...
July 26, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/28671425/slipped-capital-femoral-epiphysis-diagnosis-and-management
#16
David M Peck, Lisa M Voss, Tyler T Voss
Slipped capital femoral epiphysis (SCFE) is the most common hip disorder in adolescents, occurring in 10.8 per 100,000 children. SCFE usually occurs in those eight to 15 years of age and is one of the most commonly missed diagnoses in children. SCFE is classified as stable or unstable based on the stability of the physis. It is associated with obesity, growth spurts, and (occasionally) endocrine abnormalities such as hypothyroidism, growth hormone supplementation, hypogonadism, and panhypopituitarism. Patients with SCFE usually present with limping and poorly localized pain in the hip, groin, thigh, or knee...
June 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/28669665/the-fadir-test-accuracy-for-screening-cam-and-pincer-morphology-in-youth-ice-hockey-players
#17
Nicola C Casartelli, Romana Brunner, Nicola A Maffiuletti, Mario Bizzini, Michael Leunig, Christian W Pfirrmann, Reto Sutter
OBJECTIVES: Aim of this study was to evaluate the flexion-adduction-internal rotation (FADIR) test accuracy for screening cam and pincer morphology in youth male ice hockey players without diagnosed hip disorders. DESIGN: Cross-sectional study. METHODS: Seventy-four ice hockey players with a mean age of 16 years (range: 13-20 years) were assessed unilaterally. The presence of cam and pincer morphology was evaluated using the FADIR test and magnetic resonance imaging (MRI) (reference standard)...
June 21, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28659053/posterior-hip-approach-yields-better-functional-results-vis-%C3%A3-vis-anterolateral-approach-in-total-hip-arthroplasty-for-patients-with-severe-hip-dysplasia-a-prospective-randomized-controlled-clinical-study
#18
Faruk Mehmet Çatma, Alper Öztürk, Serhan Ünlü, Önder Ersan, Murat Altay
OBJECTIVES: We aimed to compare functional outcomes of two common hip approaches for patients with severe hip dysplasia in total hip replacement (THR) surgery. MATERIALS AND METHODS: Seventy hips of 68 patients randomized into two groups with regard to hip approach as posterior (group I) and anterolateral (group II). All patients underwent THR surgery with femoral shortening osteotomy. The groups were compared for operation time, preoperative and 6 months after abductor muscle strengths (AMSs), gait disorders, union time of the osteotomied site and dislocation rates...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28657919/asynchronous-slipped-capital-femoral-epiphysis-in-a-patient-with-a-seizure-disorder-case-report-and-review-of-the-literature
#19
Diana C Patterson, Andrew E Price
Debate remains about the appropriate treatment of the asymptomatic side following treatment of a unilateral slipped capital femoral epiphysis (SCFE). A 12-year-old boy with a seizure disorder presented with an unstable SCFE on the left hip following a seizure. He underwent percutaneous pinning of the left only. At 8 months postoperatively, he returned with an unstable slip of the right hip, again following a seizure. No literature discussing the treatment of patients with risk of SCFE and seizure disorders was identified...
June 27, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28655564/enhanced-limbic-impaired-cortical-loop-connection-onto-the-hippocampus-of-nhe-rats-application-of-resting-state-functional-connectivity-in-a-preclinical-adhd-model
#20
F Zoratto, G M Palombelli, L A Ruocco, E Carboni, G Laviola, A G Sadile, W Adriani, R Canese
Due to a hyperfunctioning mesocorticolimbic system, Naples-High-Excitability (NHE) rats have been proposed to model for the meso-cortical variant of attention deficit/hyperactivity disorder (ADHD). Compared to Naples Random-Bred (NRB) controls, NHE rats show hyperactivity, impaired non-selective attention (Aspide et al., 1998), and impaired selective spatial attention (Ruocco et al., 2009a, 2014). Alteration in limbic functions has been proposed; however, resulting unbalance among forebrain areas has not been assessed yet...
June 26, 2017: Behavioural Brain Research
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