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https://www.readbyqxmd.com/read/28306258/liquid-structure-of-bis-trifluoromethylsulfonyl-imide-based-ionic-liquids-assessed-by-ft-ir-spectroscopy
#1
Cassie Kimble, Christopher M Burba
Ionic liquids are a fertile and active area of research, in part, due to the unique properties these solvents offer over traditional molecular solvents. Since these properties are rooted in the fundamental ion-ion interactions that govern liquid structure, there is a strong motivation to characterize liquid structure. Infrared spectroscopy is a standard analytical tool for assessing the liquid structure, for the intramolecular vibrational modes of the composing the materials are often quite sensitive to the local environment about a given ion...
March 17, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28292562/a-quantitative-analysis-of-multilineage-differentiating-stress-enduring-muse-cells-in-human-adipose-tissue-and-efficacy-of-melanocytes-induction
#2
Takeshi Yamauchi, Kenshi Yamasaki, Kenichiro Tsuchiyama, Saaya Koike, Setsuya Aiba
We have shown previously that multilineage-differentiating stress-enduring (Muse) cells in neonatal fibroblasts can differentiate into functional melanocytes. In this study, we quantitate Muse cells in adipose-mesenchymal stem cells (adipose-MSCs) of human subcutaneous tissue obtained from 11 subjects of various ages, and measured efficacy of melanocytes induction from Adipose-MSC-derived Muse cells (hASC-Muse cells). There was a statistically significant negative correlation between the age of donors and the numbers of adipose-MSCs recovered per g fat as well as the percentage of SSEA3+ cells in the adipose-MSC populations, but isolated hASC-Muse cells showed pluripotency and growth curves equally regardless the age of donors...
March 6, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28287974/low-complexity-multidimensional-dct-approximations-for-high-order-tensor-data-decorrelation
#3
Vitor A Coutinho, Renato J Cintra, Fabio M Bayer
In this paper, we introduce low-complexity multidimensional discrete cosine transform (DCT) approximations. Three dimensional DCT (3D DCT) approximations are formalized in terms of high-order tensor theory. The formulation is extended to higher dimensions with arbitrary lengths. Several multiplierless 8 ˆ 8 ˆ 8 approximate methods are proposed and the computational complexity is discussed for the general multidimensional case. The proposed methods complexity cost was assessed, presenting considerably lower arithmetic operations when compared with the exact 3D DCT...
March 8, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28287970/dct-regularized-extreme-visual-recovery
#4
Yunhe Wang, Chang Xu, Shan You, Chao Xu, Dacheng Tao
Here we study the extreme visual recovery problem, in which over 90% of pixel values in a given image are missing. Existing low rank-based algorithms are only effective for recovering data with at most 90% missing values. Thus, we exploit visual data's smoothness property to help solve this challenging extreme visual recovery problem. Based on the Discrete Cosine Transform (DCT), we propose a novel DCT regularizer that involves all pixels and produces smooth estimations in any view. Our theoretical analysis shows that the total variation (TV) regularizer, which only achieves local smoothness, is a special case of the proposed DCT regularizer...
March 6, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28277872/assessing-the-stability-of-lamotrigine-dispersible-chewable-tablets-when-stored-in-blister-punch-cards
#5
Héctor R Loscertales, Pilar Modamio, Cecilia F Lastra, Eduardo L Mariño
OBJECTIVES: To determine the stability of lamotrigine dispersible/chewable tablets (DCT) when stored in blister punch cards (BPCs). METHODS: Lamotrigine 100 mg DCT were randomly repackaged into a U.S. Pharmacopeia Class A one-week cold-sealed BPC. Chemical and physical stability were evaluated over a 60-day period, in controlled conditions corresponding to Climatic Zones I/II (25°C ± 2°C; 60% ± 5% relative humidity). At scheduled times, various tests were performed on tablets in their primary packaging (reference samples) and on tablets repackaged (BPC samples)...
February 20, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28276077/quantifying-the-reproducibility-of-lung-ventilation-images-between-4-dimensional-cone-beam-ct-and-4-dimensional-ct
#6
Henry C Woodruff, Chun-Chien Shieh, Fiona Hegi-Johnson, Paul J Keall, John Kipritidis
PURPOSE: Deformable image registration (DIR) based computed tomography ventilation imaging derived from four-dimensional cone-beam CT (CTVI(4)(DCBCT) ) can complement existing 4DCT-based methods (CTVI(4)(DCT) ) to track lung function changes over a course of lung cancer radiation therapy. However the accuracy of CTVI(4)(DCBCT) needs to be assessed since anatomic 4DCBCT has demonstrably poor image quality and small field of view (FOV) compared to treatment planning 4DCT. We perform a direct comparison between short interval CTVI(4)(DCBCT) and CTVI(4)(DCT) pairs to understand the patient specific image quality factors affecting the intermodality CTVI reproducibility in the clinic...
March 9, 2017: Medical Physics
https://www.readbyqxmd.com/read/28268540/robust-watermarking-in-non-roi-of-medical-images-based-on-dct-dwt
#7
M Jamali, S Samavi, N Karimi, S M R Soroushmehr, K Ward, K Najarian
Increasing demand and utilization of telemedicine require transmission of medical information and images over internet. Since authenticity of received images is crucial and patient's information should be included with minimum changes in images, robust watermarking schemes are needed. In this paper, we propose a robust watermark method that embeds patient's information outside the region of interest (ROI) in medical image. In order to find appropriate regions for embedding, we use saliency as a means of measuring importance of regions and find blocks having minimum overlap with the ROI...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28249010/tfap2-paralogs-regulate-melanocyte-differentiation-in-parallel-with-mitf
#8
Hannah E Seberg, Eric Van Otterloo, Stacie K Loftus, Huan Liu, Greg Bonde, Ramakrishna Sompallae, Derek E Gildea, Juan F Santana, J Robert Manak, William J Pavan, Trevor Williams, Robert A Cornell
Mutations in the gene encoding transcription factor TFAP2A result in pigmentation anomalies in model organisms and premature hair graying in humans. However, the pleiotropic functions of TFAP2A and its redundantly-acting paralogs have made the precise contribution of TFAP2-type activity to melanocyte differentiation unclear. Defining this contribution may help to explain why TFAP2A expression is reduced in advanced-stage melanoma compared to benign nevi. To identify genes with TFAP2A-dependent expression in melanocytes, we profile zebrafish tissue and mouse melanocytes deficient in Tfap2a, and find that expression of a small subset of genes underlying pigmentation phenotypes is TFAP2A-dependent, including Dct, Mc1r, Mlph, and Pmel...
March 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28237146/is-routine-histopathological-examination-of-dacryocystorhinostomy-dacryocystectomy-specimens-necessary-a-tertiary-eye-hospital-experience
#9
Hind Alkatan, Majed Al-Qurashi
PURPOSE: Limited literature documenting the incidence of unsuspected malignant neoplasm among dacryocystorhinostomy/Dacryocystectomy (DCR/DCT) specimens is reviewed to determine if routine biopsy of all the patients undergoing such procedures is required. We are evaluating if sending lacrimal sac specimens for histopathological examination is necessary as a routine patient's care standard. STUDY DESIGN: This is a retrospective study of all lacrimal sac specimens received for histopathological examination in a tertiary eye hospital over a period of 12 years...
February 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28226716/robust-watermarking-in-non-roi-of-medical-images-based-on-dct-dwt
#10
M Jamali, S Samavi, N Karimi, S M R Soroushmehr, K Ward, K Najarian, M Jamali, S Samavi, N Karimi, S M R Soroushmehr, K Ward, K Najarian, K Ward, S M R Soroushmehr, M Jamali, S Samavi, K Najarian, N Karimi
Increasing demand and utilization of telemedicine require transmission of medical information and images over internet. Since authenticity of received images is crucial and patient's information should be included with minimum changes in images, robust watermarking schemes are needed. In this paper, we propose a robust watermark method that embeds patient's information outside the region of interest (ROI) in medical image. In order to find appropriate regions for embedding, we use saliency as a means of measuring importance of regions and find blocks having minimum overlap with the ROI...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28199219/clinical-applications-of-near-infrared-diffuse-correlation-spectroscopy-and-tomography-for-tissue-blood-flow-monitoring-and-imaging
#11
Yu Shang, Ting Li, Guoqiang Yu
Near-infrared (NIR) light enables the deep tissue investigation of microvascular hemodynamics. Blood flow is one such available observable promoting a wealth of physiological insight both individually and in combination with other metrics. Diffuse correlation spectroscopy (DCS) and, to a lesser extent, diffuse correlation tomography (DCT), have received interest over the past two decades as noninvasive methods for tissue blood flow measurement and imaging. DCS employs coherent point-illumination NIR light to penetrate deep tissues and commonly uses avalanche photodiodes to detect temporal speckle fluctuations of the diffuse light in a single speckle area of tissue surface, which are sensitive to the motions of red blood cells in the microvasculature of the detected tissue volume...
February 15, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28194788/protein-kinase-a-regulates-c-terminally-truncated-cav-1-2-in-xenopus-oocytes-roles-of-n-and-c-termini-of-the-%C3%AE-1c-subunit
#12
Shimrit Oz, Ines Pankonien, Anouar Belkacemi, Veit Flockerzi, Enno Klussmann, Hannelore Haase, Nathan Dascal
β-Adrenergic stimulation enhances Ca(2+) currents via L-type, voltage-gated CaV 1.2 channels, strengthening cardiac contraction. The signaling via β-adrenergic receptors (β-ARs) involves elevation of cyclic AMP (cAMP) levels and activation of protein kinase A (PKA). However, how PKA affects the channel remains controversial. Recent studies in heterologous systems and genetically engineered mice stress the importance of the posttranslational proteolytic truncation of distal C-terminus (dCT) of the main (α1C ) subunit...
February 14, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28194221/a-removal-of-eye-movement-and-blink-artifacts-from-eeg-data-using-morphological-component-analysis
#13
Balbir Singh, Hiroaki Wagatsuma
EEG signals contain a large amount of ocular artifacts with different time-frequency properties mixing together in EEGs of interest. The artifact removal has been substantially dealt with by existing decomposition methods known as PCA and ICA based on the orthogonality of signal vectors or statistical independence of signal components. We focused on the signal morphology and proposed a systematic decomposition method to identify the type of signal components on the basis of sparsity in the time-frequency domain based on Morphological Component Analysis (MCA), which provides a way of reconstruction that guarantees accuracy in reconstruction by using multiple bases in accordance with the concept of "dictionary...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28191461/three-class-mammogram-classification-based-on-descriptive-cnn-features
#14
M Mohsin Jadoon, Qianni Zhang, Ihsan Ul Haq, Sharjeel Butt, Adeel Jadoon
In this paper, a novel classification technique for large data set of mammograms using a deep learning method is proposed. The proposed model targets a three-class classification study (normal, malignant, and benign cases). In our model we have presented two methods, namely, convolutional neural network-discrete wavelet (CNN-DW) and convolutional neural network-curvelet transform (CNN-CT). An augmented data set is generated by using mammogram patches. To enhance the contrast of mammogram images, the data set is filtered by contrast limited adaptive histogram equalization (CLAHE)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28154463/association-of-gingivitis-with-dental-calculus-thickness-or-dental-calculus-coverage-and-subgingival-bacteria-in-feline-leukemia-virus-and-feline-immunodeficiency-virus-negative-cats
#15
Naris Thengchaisri, Jörg M Steiner, Jan S Suchodolski, Panpicha Sattasathuchana
Periodontal disease is the most common oral disease in cats. The objectives of this study were to determine the relationships between gingivitis and dental calculus thickness (DCT), or dental calculus coverage (DCC); determine the association of gingivitis scores and types of oral bacteria; and to evaluate bacterial co-infection in cats with periodontal disease. Twelve cats that were not infected with feline leukemia or feline immunodeficiency viruses were enrolled in the study. Gingivitis, DCT, and DCC were scored and recorded...
January 2017: Canadian Journal of Veterinary Research, Revue Canadienne de Recherche Vétérinaire
https://www.readbyqxmd.com/read/28121186/goldmann-applanation-tonometry-versus-dynamic-contour-tonometry-after-vitrectomy-with-silicone-oil-endotamponade
#16
Matthias Fuest, Nikolaos Mamas, Peter Walter, Babac E Mazinani, Gemot Roessler, Niklas Plange
PURPOSE: To evaluate the agreement of intraocular pressure (IOP) measurements using dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT) in eyes after vitrectomy with silicone oil endotamponade and controls. METHODS: In this prospective comparative study, IOP was measured with GAT and DCT in 30 eyes with oil endotamponade 1-3 days after vitrectomy and 40 untreated controls. In addition, ocular pulse amplitude (OPA), corneal pachymetry (CCT), and axial length (AL) were measured...
January 25, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28104912/paclitaxel-resistant-cancer-cell-derived-secretomes-elicit-abcb1-associated-docetaxel-cross-resistance-and-escape-from-apoptosis-through-foxo3a-driven-glycolytic-regulation
#17
Mark Borris D Aldonza, Ji-Young Hong, Sang Kook Lee
Chemotherapy-induced cancer cell secretomes promote resistance due, in part, to a predominant glycolytic energy metabolism, which drives aggressive cancer cell proliferation. However, the characterization of these secretomes and the molecular events that associate them with acquired drug resistance remain poorly understood. In this study, we show that secretomes of cancer cells with high-level paclitaxel resistance stimulated cell proliferation and suppressed drug-induced apoptosis of drug-sensitive cells. We also found that drug (docetaxel)-stimulated induction of interferon-α (IFN-α), IFN-λ and tumor necrosis factor-α (TNF-α) release in drug-sensitive cells was lowered by these secretomes...
January 20, 2017: Experimental & Molecular Medicine
https://www.readbyqxmd.com/read/28104549/mechanisms-of-silver_nanoparticles-induced-hypopigmentation-in-embryonic-zebrafish
#18
Lian Xu, Qin-Han Xu, Xin-Ying Zhou, Li-Yan Yin, Peng-Peng Guan, Ting Zhang, Jing-Xia Liu
Silver_nanoparticles (AgNPs) have been reported to inhibit specification of erythroid cells and to induce spinal cord deformities and cardiac arrhythmia in vertebrates, but have not been implicated in development of neural crest (NC) and pigment cells in an in vivo model yet. In current study, down-regulated expressions of NC genes pax7 and foxd3, melanophore genes mitfa and dct, and xanthophore gene gch2 in AgNPs-exposed embryos were revealed by microarray, qRT-PCR and whole-mount in situ hybridization (WISH)...
March 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28100643/fluid-shear-stress-increases-transepithelial-transport-of-ca2-in-ciliated-distal-convoluted-and-connecting-tubule-cells
#19
Sami G Mohammed, Francisco J Arjona, Femke Latta, René J M Bindels, Ronald Roepman, Joost G J Hoenderop
In kidney, transcellular transport of Ca(2+) is mediated by transient receptor potential vanilloid 5 and Na(+)-Ca(2+) exchanger 1 proteins in distal convoluted and connecting tubules (DCT and CNT, respectively). It is not yet understood how DCT/CNT cells can adapt to differences in tubular flow rate and, consequently, Ca(2+) load. This study aims to elucidate the molecular mechanisms by which DCT/CNT cells sense fluid dynamics to control transepithelial Ca(2+) reabsorption and whether their primary cilia play an active role in this process...
January 18, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28095579/development-and-clinical-assessment-of-a-comprehensive-product-for-pigmentation-control-in-multiple-ethnic-populations
#20
Elizabeth T Makino, Kuniko Kadoya, Monya L Sigler, Peter D Hino, Rahul C Mehta
BACKGROUND: Pigmentary changes in people of different ethnic origins are controlled by slight variations in key biological pathways leading to different outcomes from the same treatment. It is important to develop and test products for desired outcomes in varying ethnic populations. OBJECTIVES: To develop a comprehensive product (LYT2) that affects all major biological pathways controlling pigmentation and test for clinical efficacy and safety in different ethnic populations...
December 1, 2016: Journal of Drugs in Dermatology: JDD
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