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https://www.readbyqxmd.com/read/28798755/pearl-millet-genetic-traits-shape-rhizobacterial-diversity-and-modulate-rhizosphere-aggregation
#1
Papa M S Ndour, Mariama Gueye, Mohamed Barakat, Philippe Ortet, Marie Bertrand-Huleux, Anne-Laure Pablo, Damien Dezette, Lydie Chapuis-Lardy, Komi Assigbetsé, Ndjido Ardo Kane, Yves Vigouroux, Wafa Achouak, Ibrahima Ndoye, Thierry Heulin, Laurent Cournac
Root exudation contributes to soil carbon allocation and also to microbial C and energy supply, which subsequently impacts soil aggregation around roots. Biologically-driven soil structural formation is an important driver of soil fertility. Plant genetic determinants of exudation and more generally of factors promoting rhizosphere soil aggregation are largely unknown. Here, we characterized rhizosphere aggregation in a panel of 86 pearl millet inbred lines using a ratio of root-adhering soil dry mass per root tissue dry mass (RAS/RT)...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28792713/investigation-of-fc-receptor-like-3-fcrl-3-gene-polymorphism-rs7528684-with-susceptibility-to-allergic-asthma-in-iranian-north-western-azeri-population
#2
Lida Aslanian-Kalkhoran, Daniel Elieh-Ali-Komi, Mahnaz Sadeghi-Shabestari, Dariush Shanebandi, Zohreh Babaloo, Alireza Razavi, Saeed Sadigh-Eteghad, Tohid Kazemi
BACKGROUND: Asthma is a clinical setting in which multiple cellular and molecular mechanisms are involved. Additionally, increasing genetic studies have provided evidence that single nucleotide polymorphisms (SNPs) in asthma relevant genes confer susceptibility to the disease. Fc receptor-like (FCRL) 3, a transmembrane molecule basically involved in B-cell signaling, mediates immune-disorders including allergy. Aim of study was to investigate the possible association of rs7528684 SNP in FCRL3 gene with a predisposition to allergic asthma in Iranian North-western Azeri population...
July 1, 2017: Clinical Laboratory
https://www.readbyqxmd.com/read/28755230/mitochondrial-molecular-markers-for-resistance-to-bayoud-disease-in-date-palm
#3
Amgad A Saleh, Anwar H Sharafaddin, Mahmoud H El-Komy, Yasser E Ibrahim, Younis K Hamad, Younis Y Molan
Bayoud disease, caused by Fusarium oxysporum f. sp. albedinis, is a very serious and destructive disease to date palm. Screening of date palm germplasm for resistance to bayoud disease is a crucial step to avoid or alleviate the disease consequences. Fortunately, it was discovered that there are two mitochondrial plasmid-like DNA molecules associated with susceptibility or resistance to bayoud disease. In this chapter, we present a fast, simple, and reliable technique to screen date palm germplasm for the presence of these mitochondrial molecular markers associated with susceptibility or resistance to bayoud...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28738081/comparative-molecular-analyses-of-invasive-fall-armyworm-in-togo-reveal-strong-similarities-to-populations-from-the-eastern-united-states-and-the-greater-antilles
#4
Rodney N Nagoshi, Djima Koffi, Komi Agboka, Kodjo Agbeko Tounou, Rahul Banerjee, Juan Luis Jurat-Fuentes, Robert L Meagher
The fall armyworm (Spodoptera frugiperda, J.E. Smith) is a noctuid moth that is a major and ubiquitous agricultural pest in the Western Hemisphere. Infestations have recently been identified in several locations in Africa, indicating its establishment in the Eastern Hemisphere where it poses an immediate and significant economic threat. Genetic methods were used to characterize noctuid specimens infesting multiple cornfields in the African nation of Togo that were tentatively identified as fall armyworm by morphological criteria...
2017: PloS One
https://www.readbyqxmd.com/read/28725969/mastocytosis-from-a-molecular-point-of-view
#5
REVIEW
Daniel Elieh Ali Komi, Todd Rambasek, Stefan Wöhrl
Mast cells (MCs) are physiologically activated by binding of stem cell factor (SCF) to the extracellular domains of the Kit receptor. This binding increases the proliferation and prolongs the survival of normal mature MCs, as well as intensifies the release of mediators. In mastocytosis, somatic mutations of the coding Kit gene cause autocrine dysregulation and lead to constitutive KIT activation even in the absence of its ligand SCF. Clinical symptoms are caused by MC-mediator release and/or infiltration of MCs into tissues...
July 19, 2017: Clinical Reviews in Allergy & Immunology
https://www.readbyqxmd.com/read/28608701/a-two-patch-prey-predator-model-with-predator-dispersal-driven-by-the-predation-strength
#6
Yun Kang, Sourav Kumar Sasmal, Komi Messan
Foraging movements of predator play an important role in population dynamics of prey-predator systems, which have been considered as mechanisms that contribute to spatial self-organization of prey and predator. In nature, there are many examples of prey-predator interactions where prey is immobile while predator disperses between patches non-randomly through different factors such as stimuli following the encounter of a prey. In this work, we formulate a Rosenzweig-MacArthur prey-predator two patch model with mobility only in predator and the assumption that predators move towards patches with more concentrated prey-predator interactions...
August 1, 2017: Mathematical Biosciences and Engineering: MBE
https://www.readbyqxmd.com/read/28603828/profile-of-bone-malignancy-among-rheumatology-inpatients-in-lom%C3%A3-togo
#7
Kodjo Kakpovi, Owonayo Oniankitan, Messanvi Kpoti, Prénam Houzou, Viwalé Es Koffi-Tessio, Komi C Tagbor, Eyram Fianyo, Moustafa Mijiyawa
BACKGROUND: The incidence of bone malignancy in adulthood seems poorly known in Black Africa. AIM: To determine the epidemiological, clinical, and paraclinical profile of bone malignancy in patients admitted to the Rheumatology Department in Lomé (Togo). METHODS: A retrospective study was conducted over 19 years on records of hospital patients admitted for bone malignancy. RESULTS: One hundred sixty-six of 2018 (8.2%) patients (98 men and 68 women) admitted suffered from bone malignancy...
August 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/28599803/long-term-effects-of-the-2011-japan-earthquake-and-tsunami-on-incidence-of-fatal-and-nonfatal-myocardial-infarction
#8
Motoyuki Nakamura, Kentarou Tanaka, Fumitaka Tanaka, Yuuki Matsuura, Ryousuke Komi, Masanobu Niiyama, Mikio Kawakami, Yorihiko Koeda, Toshiaki Sakai, Toshiyuki Onoda, Tomonori Itoh
This study aimed to examine the long-term effects of the 2011 Japan earthquake and tsunami on the incidence of fatal and nonfatal myocardial infarction (MI). In the present study, the incidence of 2 types of cardiac events was comprehensively recorded. The study area was divided into 2 zones based on the severity of tsunami damage, which was determined by the percentage of the inundated area within the residential area (<10%, low-impact zone and ≥10%, high-impact zone). The standardized incidence ratio (SIR) and 95% CI for both types of cardiac events during the disaster year and the postdisaster years were determined in each zone...
August 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28596780/katanin-effects-on-dynamics-of-cortical-microtubules-and-mitotic-arrays-in-arabidopsis-thaliana-revealed-by-advanced-live-cell-imaging
#9
George Komis, Ivan Luptovčiak, Miroslav Ovečka, Despina Samakovli, Olga Šamajová, Jozef Šamaj
Katanin is the only microtubule severing protein identified in plants so far. Previous studies have documented its role in regulating cortical microtubule organization during cell growth and morphogenesis. Although, some cell division defects are reported in KATANIN mutants, it is not clear whether or how katanin activity may affect microtubule dynamics in interphase cells, as well as the progression of mitosis and cytokinesis and the orientation of cell division plane (CDP). For this reason, we characterized microtubule organization and dynamics in growing and dividing cotyledon cells of Arabidopsis ktn1-2 mutant devoid of KATANIN 1 activity...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28582732/the-dynamics-and-endocytosis-of-flot1-protein-in-response-to-flg22-in-arabidopsis
#10
Meng Yu, Haijiao Liu, Ziyi Dong, Jianwei Xiao, Bodan Su, Lusheng Fan, George Komis, Jozef Šamaj, Jinxing Lin, Ruili Li
Membrane microdomains play vital roles in the process of bacterial infection. The membrane microdomain-associated protein Flot1 acts in an endocytic pathway and is required for seedling development, however, whether Flot1 is a part of host defense mechanisms remains unknown. During an analysis of callose deposition, we found that Flot1 amiRNAi mutants exhibited defects in response to flg22. Using variable-angle total internal reflection fluorescence microscopy (VA-TIRFM), structured illumination microscopy (SIM) and fluorescence cross spectroscopy (FCS), we determined that the dynamic behavior of GFP-Flot1 in Arabidopsis thaliana cotyledon epidermal cells changed significantly in plants treated with the elicitor flg22...
May 19, 2017: Journal of Plant Physiology
https://www.readbyqxmd.com/read/28529520/katanin-1-is-essential-for-embryogenesis-and-seed-formation-in-arabidopsis
#11
Ivan Luptovčiak, Despina Samakovli, George Komis, Jozef Šamaj
Cytoskeletal remodeling has a fundamental role, especially during transitional developmental stages when cells rapidly adopt new forms and roles, like gametogenesis, fertilization and concomitant embryogenesis and seed formation. KATANIN 1, a microtubule severing protein, fulfills a major regulatory mechanism of dynamic microtubule turnover in eukaryotes. Herein, we show that three well-established KATANIN 1 mutants, fra2, lue1 and ktn1-2 collectively display lower fertility and seed set in Arabidopsis. These lower fertility and seed set rates of fra2, lue1 and ktn1-2 mutants were correlated to abnormalities in the development of embryo proper and seed...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28527688/clinical-development-of-a-var2csa-based-placental-malaria-vaccine-pamvac-quantifying-vaccine-antigen-specific-memory-b-t-cell-activity-in-beninese-primigravidae
#12
Komi Gbédandé, Nadine Fievet, Firmine Viwami, Sem Ezinmegnon, Saadou Issifou, Jean-Philippe Chippaux, Yannelle Dossou, Kabirou Moutairou, Achille Massougbodji, Nicaise Ndam, Willem Adriaan de Jongh, T Max M Søgaard, Ali Salanti, Morten A Nielsen, Meral Esen, Benjamin Mordmüller, Philippe Deloron, Adrian J F Luty
BACKGROUND: The antigen VAR2CSA plays a pivotal role in the pathophysiology of pregnancy-associated malaria (PAM) caused by Plasmodium falciparum. A VAR2CSA-based vaccine candidate, PAMVAC, is under development by an EU-funded multi-country consortium (PlacMalVac project). As part of PAMVAC's clinical development, we quantified naturally acquired vaccine antigen-specific memory B and T cell responses in Beninese primigravidae recruited at the beginning of pregnancy and followed up to delivery and beyond...
May 17, 2017: Vaccine
https://www.readbyqxmd.com/read/28509576/her2-positivity-may-confer-resistance-to-therapy-with-paclitaxel-in-breast-cancer-cell-lines
#13
Navideh Haghnavaz, Faezeh Asghari, Daniel Elieh Ali Komi, Dariush Shanehbandi, Behzad Baradaran, Tohid Kazemi
INTRODUCTION: MicroRNAs (miRNAs) are short non-coding single-stranded RNAs. Involving in post-transcriptional gene silencing, miRNAs are thought to play important roles in many cancers such as breast cancer. Paclitaxel is used widely in the treatment of breast cancer. In this study, we investigated the effect of paclitaxel treatment on the expression levels of two oncomirs (oncomiRs), miR-21 and miR-203, in breast cancer cell lines. MATERIALS AND METHODS: MTT assay was performed to determine IC50 of paclitaxel for human breast cancer cell lines including MCF-7, MDA-MB-231, SKBR3 and BT-474...
May 16, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/28501343/changes-of-renal-sinus-fat-and-renal-parenchymal-fat-during-an-18-month-randomized-weight-loss-trial
#14
Hila Zelicha, Dan Schwarzfuchs, Ilan Shelef, Yftach Gepner, Gal Tsaban, Lilac Tene, Anat Yaskolka Meir, Avital Bilitzky, Oded Komy, Noa Cohen, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Yoash Chassidim, Benjamin Sarusi, Joachim Thiery, Uta Ceglarek, Michael Stumvoll, Matthias Blüher, Yosef S Haviv, Meir J Stampfer, Assaf Rudich, Iris Shai
BACKGROUND & AIMS: Data regarding the role of kidney adiposity, its clinical implications, and its dynamics during weight-loss are sparse. We investigated the effect of long-term weight-loss induced intervention diets on dynamics of renal-sinus-fat, an ectopic fat depot, and %renal-parenchymal-fat, lipid accumulation within the renal parenchyma. METHODS: We randomized 278 participants with abdominal obesity/dyslipidemia to low-fat or Mediterranean/low-carbohydrate diets, with or without exercise...
May 2, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28462166/papillary-renal-cell-carcinoma-revealed-by-renal-traumatism-a-case-report-in-lom%C3%A3
#15
Tchilabalo Matchonna Kpatcha, Kodjo Tengué, Gnimdou Botcho, Tchin Darré, Kossi Akomola Sabi, Komi Hola Sikpa, Essomendedou Léloua, Edoé Viyomé Séwa, Obube Amegayibor, Tsipa Anoukoum, Koffi Amégbor, Ekoue David Dosseh
This study is a report on a case of papillary carcinoma of the kidney revealed by an abdominal contusion. The results of radiological investigations were discordant with the low intensity of the shock. The treatment consisted of radical nephrectomy because of the suspicion of a pre-existing malignancy. Histological analysis revealed a papillary carcinoma pT3N0M0. We focus on the need for performing diagnostic tests in order to avoid missing a pre-existing anomaly to the kidney trauma.
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28448406/two-dimensional-spoiled-gradient-recalled-echo-magnetic-resonance-imaging-of-the-liver-using-respiratory-navigator-gating-techniques
#16
Yusuke Inoue, Hirofumi Hata, Keiji Matsunaga, Ai Nakajima, Shotaro Komi, Yutaka Abe, Hiroki Miyatake
OBJECTIVE: We assessed the feasibility of T1-weighted 2-dimensional spoiled gradient-recalled (2D SPGR) acquisition in steady-state imaging of the liver with various respiratory navigator gating techniques. METHODS: A total of 12 healthy volunteers underwent in-phase and out-of-phase 2D SPGR imaging of the liver during breath-holding and free-breathing. Four techniques for respiratory navigation, 2 conventional navigator techniques and 2 self-navigator techniques, were used for free-breathing imaging...
April 26, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28433730/detection-of-rickettsia-helvetica-and-candidatus-r-tarasevichiae-dna-in-ixodes-persulcatus-ticks-collected-in-northeastern-european-russia-komi-republic
#17
Mikhail Yu Kartashov, Ludmila I Glushkova, Tamara P Mikryukova, Igor V Korabelnikov, Yulia I Egorova, Natalia L Tupota, Elena V Protopopova, Svetlana N Konovalova, Vladimir A Ternovoi, Valery B Loktev
The number of tick-borne infections in the northern European regions of Russia has increased considerably in the last years. In the present study, 676 unfed adult Ixodes persulcatus ticks were collected in the Komi Republic from 2011 to 2013 to study tick-borne rickettsioses. Rickettsia spp. DNA was detected by PCR in 51 (7.6%) ticks. The nucleotide sequence analysis of gltA fragments (765bp) from 51 ticks indicated that 60.8% and 39.2% of the ticks were infected with Rickettsia helvetica and Candidatus R. tarasevichiae, respectively...
April 6, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28362566/impact-of-air-temperature-variation-on-the-ixodid-ticks-habitat-and-tick-borne-encephalitis-incidence-in-the-russian-arctic-the-case-of-the-komi-republic
#18
N Tokarevich, A Tronin, B Gnativ, B Revich, O Blinova, B Evengard
BACKGROUND: The causes of the recent rise of tick-borne encephalitis (TBE) incidence in Europe are discussed. Our objective was to estimate the impact of air temperature change on TBE incidence in the European part of the Russian Arctic. METHODS: We analysed the TBE incidence in the Komi Republic (RK) over a 42-year period in relation to changes in local annual average air temperature, air temperature during the season of tick activity, tick abundance, TBE-prevalence in ticks, tick-bite incidence rate, and normalised difference vegetation index within the area under study...
2017: International Journal of Circumpolar Health
https://www.readbyqxmd.com/read/28355949/differences-in-the-suppression-of-distortion-product-otoacoustic-emissions-by-contralateral-white-noise-between-patients-with-acute-or-chronic-tinnitus
#19
Maria Riga, Agis Komis, Pavlos Marangoudakis, Stefanos Naxakis, Eleftherios Ferekidis, Dimitrios Kandiloros, Vasilios Danielides
OBJECTIVE: The mechanisms underlying the shift from acute tinnitus to chronic remain obscure. An association between tinnitus and medial olivocochlear bundle (MOCB) reflex dysfunction has been hypothesised by several studies. The differences between participants with acute and chronic tinnitus have not yet been investigated. DESIGN: Participants were examined with distortion product otoacoustic emissions (DPOAEs) suppression elicited by contralateral white noise...
March 30, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28263187/aggregation-of-scaffolding-protein-disc1-dysregulates-phosphodiesterase-4-in-huntington-s-disease
#20
Motomasa Tanaka, Koko Ishizuka, Yoko Nekooki-Machida, Ryo Endo, Noriko Takashima, Hideyuki Sasaki, Yusuke Komi, Amy Gathercole, Elaine Huston, Kazuhiro Ishii, Kelvin Kai-Wan Hui, Masaru Kurosawa, Sun-Hong Kim, Nobuyuki Nukina, Eiki Takimoto, Miles D Houslay, Akira Sawa
Huntington's disease (HD) is a polyglutamine (polyQ) disease caused by aberrant expansion of the polyQ tract in Huntingtin (HTT). While motor impairment mediated by polyQ-expanded HTT has been intensively studied, molecular mechanisms for nonmotor symptoms in HD, such as psychiatric manifestations, remain elusive. Here we have demonstrated that HTT forms a ternary protein complex with the scaffolding protein DISC1 and cAMP-degrading phosphodiesterase 4 (PDE4) to regulate PDE4 activity. We observed pathological cross-seeding between DISC1 and mutant HTT aggregates in the brains of HD patients as well as in a murine model that recapitulates the polyQ pathology of HD (R6/2 mice)...
April 3, 2017: Journal of Clinical Investigation
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