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https://www.readbyqxmd.com/read/28222042/compound-effects-of-aging-and-experimental-fsgs-on-glomerular-epithelial-cells
#1
Remington R S Schneider, Diana G Eng, J Nathan Kutz, Mariya T Sweetwyne, Jeffrey W Pippin, Stuart J Shankland
Advanced age portends a poorer prognosis in FSGS. To understand the impact of age on glomerular podocytes and parietal epithelial cells (PECs), experimental FSGS was induced in 3m-old mice (20-year old human age) and 27m-old mice (78-year old human age) by abruptly depleting podocytes with a cytopathic anti-podocyte antibody. Despite similar binding of the disease-inducing antibody, podocyte density was lower in aged FSGS mice compared to young FSGS mice. Activated PEC density was higher in aged versus young FSGS mice, as was the percentage of total activated PECs...
February 17, 2017: Aging
https://www.readbyqxmd.com/read/28220996/surviving-high-temperature-calcination-zro2-induced-hematite-nanotubes-for-photoelectrochemical-water-oxidation
#2
Chengcheng Li, Ang Li, Zhibin Luo, Jijie Zhang, Xiaoxia Chang, Zhiqi Huang, Tuo Wang, Jinlong Gong
Nanotubular Fe2 O3 is a promising photoanode material, and producing morphologies that withstand high-temperature calcination (HTC) is urgently needed to enhance the photoelectrochemical (PEC) performance. This work describes the design and fabrication of Fe2 O3 nanotube arrays that survive HTC for the first time. By introducing a ZrO2 shell on hydrothermal FeOOH nanorods by atomic layer deposition, subsequent high-temperature solid-state reaction converts FeOOH-ZrO2 nanorods to ZrO2 -induced Fe2 O3 nanotubes (Zr-Fe2 O3 NTs)...
February 21, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28220288/social-cognition-according-to-cognitive-impairment-in-different-clinical-phenotypes-of-multiple-sclerosis
#3
Cecile Dulau, Mathilde Deloire, Helene Diaz, Aurore Saubusse, Julie Charre-Morin, Antoinette Prouteau, Bruno Brochet
The objective of this study is to evaluate the relationship between social cognition (SC) and cognitive impairment in persons with multiple sclerosis (PwMS). A prospective study was conducted in 60 PwMS, 30 with relapsing-remitting MS (RRMS), 15 with secondary progressive MS (SPMS) and 15 with primary progressive MS (PPMS), and in healthy subjects (HS). All subjects were assessed by the Bordeaux Social Cognition Evaluation Protocol (PECS-B) (facial emotion recognition, theory of mind, emotional awareness and cognitive and affective alexithymia), by a large neuropsychological battery and by questionnaires (depression and anxiety)...
February 20, 2017: Journal of Neurology
https://www.readbyqxmd.com/read/28220158/voltammetric-determination-of-diffusion-coefficients-in-polymer-membranes
#4
James B Sheppard, Bradley Hambly, Bradford Pendley, Erno Lindner
The diffusion-controlled transport of ions and molecules through polymer membranes utilized in chemical and biosensors is often the key factor determining the response characteristics of these sensors. In this paper, a simple voltammetric method is described for the determination of diffusion coefficients of redox molecules in resistive polymer membranes using a planar electrochemical cell (PEC) with a 5 μm radius carbon fiber as working electrode. In the proposed method, the diffusion coefficients are assessed from the scan rate dependence of the peak (or limiting) currents in linear sweep or cyclic voltammograms...
February 21, 2017: Analyst
https://www.readbyqxmd.com/read/28219249/enhanced-photoelectrochemical-method-for-sensitive-detection-of-protein-kinase-a-activity-using-tio2-g-c3n4-pamam-dendrimer-and-alkaline-phosphatase
#5
Xue Li, Lusheng Zhu, Yunlei Zhou, Huanshun Yin, Shiyun Ai
A novel photoelectrochemical (PEC) assay is developed for sensitive detection of protein kinase A (PKA) activity based on PKA-catalyzed phosphorylation reaction in solution and signal amplification strategy triggered by PAMAM dendrimer and alkaline phosphatase (ALP). In this strategy, it is noteworthy at this point that PKA phosphorylation was achieved in solution instead of on the surface of the electrode, which has advantages of the good contact in reactants and simple experimental procedure. For immobilizing the phosphorylated peptide (P-peptide) on electrode surface, graphite-like carbon nitride (g-C3N4) and titanium dioxide (TiO2) complex is synthesized and characterized, which plays a significant role for TiO2 conjugating phosphate groups and g-C3N4 providing PEC signal...
February 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28213214/bifunctional-polydopamine-thin-film-coated-zinc-oxide-nanorods-for-label-free-photoelectrochemical-immunoassay
#6
Yan Yang, Weihua Hu
Photoelectrochemical (PEC) detection is a promising method for label-free immunoassay by reporting the specific biological recognition events with electrical signals. However, it is challenging to rationally incorporate immunosensing components with a photocurrent conversion interface, which generally necessitates multistep fabrication and careful tailoring of various components such as photoactive material and biological probe. For high detection reliability and reproducibility, it is highly desirable to rationally construct an efficient PEC interface with architecture as simple as possible...
May 1, 2017: Talanta
https://www.readbyqxmd.com/read/28202348/assessment-of-environmental-risks-to-groundwater-ecosystems-related-to-use-of-veterinary-medicinal-products
#7
Boris Kolar, Antonio Finizio
The current EU guidelines for the environmental risk assessment of veterinary pharmaceutical products (VMPs) in groundwater (GW) suggest an approach based on the comparison between the calculated concentration in GW (PECgw) and a threshold concentration of 0.1 μg/L. The latter is the upper limit of the concentration for pesticides in groundwater in the EU. If the calculated PECgw does not exceed the threshold, then the risk is considered acceptable. It is assumed that the concentration of 0.1 μg/L is by default safe for both humans and exposed GW organisms...
February 12, 2017: Regulatory Toxicology and Pharmacology: RTP
https://www.readbyqxmd.com/read/28193072/semiautomated-support-photoelectrochemical-immunosensing-platform-for-portable-and-high-throughput-immunoassay-based-on-au-nanocrystal-decorated-specific-crystal-facets-bivo4-photoanode
#8
Jian Shu, Zhenli Qiu, Zhenzhen Lin, Guoneng Cai, Huanghao Yang, Dianping Tang
Photoelectrochemical (PEC) measurement has been developed rapidly for bioanalysis in recent years. However, the actual application for most existed PEC bioanalytical systems is still a challenge because the perfect solutions for sensing surface design, high-throughput detection, and portability are lacked. To successfully overcome these limitations and realize accurate, continuous screening and assessing on prognostic indicator of early stage cancer on the spot, an innovative and portable semiautomated support power-free photoelectrochemical (SP-PEC) immunosensing platform consisted with a miniature semiautomatic injection system and digital multimeter (DMM) readout is designed (prostate specific antigen, PSA, was used as the proof-of-concept analyte)...
December 20, 2016: Analytical Chemistry
https://www.readbyqxmd.com/read/28190757/consensus-bundle-on-maternal-mental-health-perinatal-depression-and-anxiety
#9
Susan Kendig, John P Keats, M Camille Hoffman, Lisa B Kay, Emily S Miller, Tiffany A Moore Simas, Ariela Frieder, Barbara Hackley, Pec Indman, Christena Raines, Kisha Semenuk, Katherine L Wisner, Lauren A Lemieux
Perinatal mood and anxiety disorders are among the most common mental health conditions encountered by women of reproductive age. When left untreated, perinatal mood and anxiety disorders can have profound adverse effects on women and their children, ranging from increased risk of poor adherence to medical care, exacerbation of medical conditions, loss of interpersonal and financial resources, smoking and substance use, suicide, and infanticide. Perinatal mood and anxiety disorders are associated with increased risks of maternal and infant mortality and morbidity and are recognized as a significant patient safety issue...
February 4, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28187300/electrospun-template-directed-molecularly-imprinted-nanofibers-incorporated-with-bioi-nanoflake-arrays-as-photoactive-electrode-for-photoelectrochemical-detection-of-triphenyl-phosphate
#10
Xiaomin Yang, Xin Li, Lizhi Zhang, Jingming Gong
Triphenyl Phosphate (TPhP), as a typical model of organophosphorus flame retardants (OPFRs), has been regarded as emerging environmental contaminants of health concern. In this study, a rapid and highly sensitive visible-light-response PEC sensor has been developed for the detection of Triphenyl Phosphate (TPhP) using electrospun template directed molecularly imprinted nanofibers modified BiOI nanoflake arrays (BiOINFs) as a photoactive electrode. The molecularly imprinted electrospun nanofibers (labeled as MI-ESNFs) were carefully characterized by scanning electron microscopy (SEM), UV spectra, FTIR spectra measurements and various electrochemical techniques...
January 26, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28186170/plasmon-enhanced-photocurrent-using-gold-nanoparticles-on-a-three-dimensional-tio2-nanowire-web-electrode
#11
Yin-Cheng Yen, Jau-An Chen, Sheng Ou, Yi-Shin Chen, Kuan-Jiuh Lin
In this study, an anatase/rutile mixed-phase titanium dioxide (TiO2) hierarchical network deposited with Au nanoparticles (Au/TiO2 ARHN) was synthesized using a facile hydrothermal method followed by a simple calcination step. Such a unique structure was designed for improving the light harvest, charge transportation/separation, and the performance of photo-electro-chemical (PEC) cells. The properties of the as-synthesized Au/TiO2 ARHN in PEC cells were investigated by electrochemical measurements using a three-electrode system in a 1 M NaOH electrolyte...
February 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28184271/surgical-excision-of-the-breast-giant-fibroadenoma-under-regional-anesthesia-by-pecs-ii-and-internal-intercostal-plane-block-a-case-report-and-brief-technical-description-a-case-report
#12
Hyungtae Kim, Junho Shim, Ikthae Kim
A 22-years-old female patient at 171 cm and 67 kg visited the Department of Breast Surgery of the hospital with a mass accompanied with pain on the left side breast as chief complaints. Since physical examination revealed a suspected huge mass, breast surgeon decided to perform surgical excision and requested anesthesia to our department. Surgery of breast tumor is often under local anesthesia. However, in case of big size tumor, surgery is usually performed under general anesthesia. The patient feared general anesthesia...
February 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28178638/fast-photoelectro-reduction-of-cr-vi-over-mos2-tio2-nanotubes-on-ti-wire
#13
Lixia Yang, Xutong Zheng, Ming Liu, Shenglian Luo, Yan Luo, Guifa Li
A stable MoS2 nanosheets@TiO2 NTAs composite was prepared via a simple hydrothermal process. Few-layer MoS2 nanosheets distributed on the TiO2 nanotube top surface and the inner walls rather than filling in the tubes, allowing abundant tubular channels open to environment and benefiting for efficient mass transport. Photocatalytic (PE) and photoelectrocatalytic (PEC) performance of the composite were evaluated on Cr(VI) reduction, with variable low molecule weight organic acids (LOAs) added as sacrificial electron donor to form a charge-transfer-complex (CTC) between LOAs and TiO2/MoS2, which is sensitive to the visible light illumination and could induce the photo-reduction of Cr(VI) and photo-oxidation of LOAs...
January 30, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28178041/consensus-bundle-on-maternal-mental-health-perinatal-depression-and-anxiety
#14
Susan Kendig, John P Keats, M Camille Hoffman, Lisa B Kay, Emily S Miller, Tiffany A Moore Simas, Ariela Frieder, Barbara Hackley, Pec Indman, Christena Raines, Kisha Semenuk, Katherine L Wisner, Lauren A Lemieux
Perinatal mood and anxiety disorders are among the most common mental health conditions encountered by women of reproductive age. When left untreated, perinatal mood and anxiety disorders can have profound adverse effects on women and their children, ranging from increased risk of poor adherence to medical care, exacerbation of medical conditions, loss of interpersonal and financial resources, smoking and substance use, suicide, and infanticide. Perinatal mood and anxiety disorders are associated with increased risks of maternal and infant mortality and morbidity and are recognized as a significant patient safety issue...
February 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28177581/harvesting-hydrogen-gas-from-air-pollutants-with-an-un-biased-gas-phase-photo-electrochemical-cell
#15
Sammy W Verbruggen, Myrthe Van Hal, Tom Bosserez, Jan Rongé, Birger Hauchecorne, Johan A Martens, Silvia Lenaerts
The concept of an all-gas-phase photo-electrochemical cell (PEC) producing hydrogen gas from volatile organic contaminated gas and light is presented. Without applying any external bias, organic contaminants are degraded and hydrogen gas is produced in separate electrode compartments. The system works most efficiently with organic pollutants in inert carrier gas. In the presence of oxygen gas, the cell performs less efficiently but still significant photocurrents are generated, showing the cell can be run on organic contaminated air...
February 8, 2017: ChemSusChem
https://www.readbyqxmd.com/read/28177218/ultrasensitive-photoelectrochemical-biosensing-of-cell-surface-n-glycan-expression-based-on-the-enhancement-of-nanogold-assembled-mesoporous-silica-amplified-by-graphene-quantum-dots-and-hybridization-chain-reaction
#16
Shenguang Ge, Feifei Lan, Linlin Liang, Na Ren, Li Li, Haiyun Liu, Mei Yan, Jinghua Yu
An ultrasensitive photoelectrochemical (PEC) biosensor for N-glycan expression based on the enhancement of nanogold-assembled mesoporous silica nanoparticles (GMSNs) was fabricated, which also combined with multibranched hybridization chain reaction (mHCR) and graphene quantum dots (GQDs). In this work, the localized surface plasmon resonance, mHCR and GQDs-induced signal amplification strategies were integrated exquisitely and applied sufficiently. In the fabrication, after porous ZnO spheres immobilized on the Au nanorod-modified paper working electrode were sensitized by CdTe QDs, the GMSNs were assembled on the CdTe QDs...
February 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28170225/plasmon-sensitized-graphene-tio2-inverse-opal-nanostructures-with-enhanced-charge-collection-efficiency-for-water-splitting
#17
Ramireddy Boppella, Saji Thomas Kochuveedu, Heejun Kim, Myung Jin Jeong, Filipe Marques Mota, Jong Hyeok Park, Dong Ha Kim
In this contribution we have developed TiO2 inverse opal based photoelectrodes for photoelectrochemical (PEC) water splitting devices, in which Au nanoparticles (NPs) and reduced graphene oxide (rGO) have been strategically incorporated (TiO2@rGO@Au). The periodic hybrid nanostructure showed a photocurrent density of 1.29 mA cm(-2) at 1.23 V vs RHE, uncovering a 2-fold enhancement compared to a pristine TiO2 reference. The Au NPs were confirmed to extensively broaden the absorption spectrum of TiO2 into the visible range and to reduce the onset potential of these photoelectrodes...
February 15, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28165199/3d-wo3-bivo4-cobalt-phosphate-composites-inverse-opal-photoanode-for-efficient-photoelectrochemical-water-splitting
#18
Haifeng Zhang, Weiwei Zhou, Yaping Yang, Chuanwei Cheng
A novel 3D WO3 /BiVO4 /cobalt phosphate composite inverse opal is designed for photoeletrochemical (PEC) water splitting, yielding a significantly improved PEC performance.
February 6, 2017: Small
https://www.readbyqxmd.com/read/28164731/regulatory-modulatory-effect-of-prune-essence-concentrate-on-intestinal-function-and-blood-lipids
#19
Hui-Fang Chiu, Yun-Chien Huang, Yan-Ying Lu, Yi-Chun Han, You-Cheng Shen, Oksana Golovinskaia, Kamesh Venkatakrishnan, Chin-Kun Wang
CONTEXT: Prunus domestica Linn (Rosaceae) has been considered a functional food, owing to its various pharmacological activities, including antioxidant, anti-inflammatory, antidiabetic and anticancer. OBJECTIVE: This placebo-controlled, randomized study was framed to check the beneficial activity of prune essence concentrates (PEC) in corroboration with intestinal function and lipid profile in mildly hypercholesterolemic subjects. MATERIALS AND METHODS: Sixty healthy mild hypercholesterolemic subjects were randomly chosen and segregated into three groups as placebo (consume 50 mL of simulated prune drink), PEC I (consume 50 mL of PEC/day) and PEC II (consume 100 mL of PEC/day) for 4 weeks with 2 weeks of follow-up without PEC consumption...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28159316/-de-novo-consultation-evaluation-of-an-outpatient-s-clinic-dedicated-to-early-diagnosis-of-parkinsonian-syndromes
#20
J Ruggeri, L-L Mariani, S Aix, A-M Bonnet, F Cormier, J-C Corvol, P Dodet, D Grabli, A Hartmann, C Hubsch, L Lacomblez, E Roze, M-L Welter, Y Worbe, M Vidailhet, B Degos
INTRODUCTION: In the absence of specific clinical signs, imaging or biomarkers, the differential diagnosis of degenerative parkinsonian syndromes may be difficult at early stages of the disease. To reduce the risk of misdiagnosis or delayed diagnosis and referral to multiple medical centers at disease onset, easier access to expert centers should be available. To improve the initial care of parkinsonian patients, the Parkinson's disease Expert Center (PEC) at Pitié-Salpêtrière Academic Hospital has set up a specific outpatients clinic with short waiting times dedicated to the diagnosis of early Parkinson's disease and related disorders...
January 31, 2017: Revue Neurologique
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