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https://www.readbyqxmd.com/read/28724270/synergistic-effects-of-ad-libitum-low-dose-fructose-drinking-and-low-dose-streptozotocin-treatment-in-wistar-rats-a-mild-model-of-type-2-diabetes
#1
Asie Sadeghi, Maani Beigy, Samira Alizadeh, Hossein Mazloom, Sanaz Vakili, Saideh Ahmadi, Reza Meshkani
To develop a convenient animal model of T2D by pretreatment with low-dose 10% w/v fructose (FRC) solution followed by the injection of low doses of streptozotocin (STZ) in Wistar rats. For this 8-week experimental study; rats were first fed a standard chow ad-libitum diet and either tap water (n=40) or 10% w/v FRC solution (n=40) for 4 weeks. Next, rats in each category were randomly allocated to 4 subgroups (n=10 each) of low-dose STZ (25,35, and 45 mg/kg). The final mean fasting blood sugar (FBG) of FRC+STZ45 (197±55...
May 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28724110/coal-bed-methane-water-effects-on-soil-properties-and-camelina-productivity
#2
Henry Y Sintim, Valtcho D Zheljazkov, Michael E Foley, Roque L Evangelista
Every year, the production of coal-bed natural gas in the Powder River Basin results in the discharge of large amounts of coal-bed methane water (CBMW) in Wyoming; however, no sustainable disposal methods for CBMW are currently available. A greenhouse study was conducted to evaluate the potential to use CBMW as a source of irrigation water for camelina [ (L.) Crantz]. We assessed the effects of three CBMW concentrations (0% [1:0], 50% [1:1], and 100% [0:1] tap water to CBMW) on selected soil properties, growth, seed oil, and fatty acid composition of three camelina cultivars: Blaine Creek, Ligena, and Pronghorn...
May 2017: Journal of Environmental Quality
https://www.readbyqxmd.com/read/28723714/vent-incisions-to-facilitate-peripheral-unfolding-of-the-dmek-graft
#3
Christopher Liu, Alfonso Vasquez-Perez, Jordan Vassileff Chervenkoff, Venkata Avadhanam
PURPOSE: To present the results of 15 cases in which a modified technique of Descemet membrane endothelial keratoplasty (DMEK) with vent incisions was used to assist unfolding of tight peripheral inward folds. METHODS: This is a retrospective case series of 15 consecutive eyes that underwent a modified vent incision technique for DMEK. Six oblique, small-size (1 mm) vent incisions parallel to the limbus and 3.5 mm from the center were performed after descemetorhexis...
July 17, 2017: Cornea
https://www.readbyqxmd.com/read/28723208/the-triple-roles-of-glutathione-for-a-dna-cleaving-dnazyme-and-development-of-a-fluorescent-glutathione-cu-2-dependent-dnazyme-sensor-for-detection-of-cu-2-in-drinking-water
#4
Shijin Wang, Chengcheng Liu, Guiying Li, Yongjie Sheng, Yanhong Sun, Hongyue Rui, Jin Zhang, Jiacui Xu, Dazhi Jiang
Pistol-like DNAzyme (PLDz) is an oxidative DNA-cleaving catalytic DNA with ascorbic acid as cofactor. Herein, glutathione was induced into the reaction system to maintain reduced ascorbic acid levels for higher efficient cleavage. However, data indicated that glutathione played triple roles in PLDz-catalyzed reactions. Glutathione alone had no effect on PLDz, and showed inhibitory effect on ascorbic acid-induced PLDz catalysis, but exhibited stimulating effect on Cu(2+)-promoted self-cleavage of PLDz. Further analysis of the effect of glutathione/Cu(2+) on PLDz indicated that H2O2 played a key role in PLDz catalysis...
March 24, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28723185/silanization-of-sapphire-surfaces-for-optical-sensing-applications
#5
Tanja Sandner, Annina M Steinbach, Peter Knittel, Thomas Diemant, R Jürgen Behm, Steffen Strehle, Christine Kranz, Boris Mizaikoff
Well-characterized silane layers are essential for optimized attachment of (bio)molecules enabling reliable chem/biosensor performance. Herein, binding properties and orientation of 3-mercaptopropyltrimethoxysilane layers at crystalline sapphire (0001) surfaces were determined by water contact angle measurements, infrared reflection absorption spectroscopy, atomic force microscopy, and X-ray photoelectron spectroscopy. Infrared reflection absorption spectroscopy measurements suggest an almost perpendicular arrangement of the MPTMS molecules to the substrate surface...
April 28, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28721534/capsule-commentary-on-gryczynski-et-al-validation-of-the-taps-1-a-four-item-screening-tool-to-identify-unhealthy-substance-use-in-primary-care
#6
Sarah M Hartz
No abstract text is available yet for this article.
July 18, 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28720878/comparison-of-dna-pma-and-rna-based-16s-rrna-illumina-sequencing-for-detection-of-live-bacteria-in-water
#7
Ru Li, Hein Min Tun, Musarrat Jahan, Zhengxiao Zhang, Ayush Kumar, Dilantha Fernando, Annemieke Farenhorst, Ehsan Khafipour
The limitation of 16S rRNA gene sequencing (DNA-based) for microbial community analyses in water is the inability to differentiate live (dormant cells as well as growing or non-growing metabolically active cells) and dead cells, which can lead to false positive results in the absence of live microbes. Propidium-monoazide (PMA) has been used to selectively remove DNA from dead cells during downstream sequencing process. In comparison, 16S rRNA sequencing (RNA-based) can target live microbial cells in water as both dormant and metabolically active cells produce rRNA...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28720600/is-the-mechanism-of-re-expansion-pulmonary-oedema-in-a-heart-lung-interaction
#8
Candy Masego Mokotedi, Martin Balik
The mechanism of re-expansion pulmonary oedema (Re-PE) is unclear. There are multiple variables in play when evaluating the response to evacuation of pleural fluid. We present an educational case of a critically ill patient admitted for respiratory failure who was fully dependent on ventricular pacing set at a constant rate throughout the episode of Re-PE. The transthoracic echocardiography (TTE) showed an ejection fraction of 38%, moderate mitral regurgitation (MR), mildly dilated right ventricle and moderate pulmonary hypertension...
July 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28720105/decomposing-the-causes-of-socioeconomic-related-health-inequality-among-urban-and-rural-populations-in-china-a-new-decomposition-approach
#9
Jiaoli Cai, Peter C Coyte, Hongzhong Zhao
BACKGROUND: In recent decades, China has experienced tremendous economic growth and also witnessed growing socioeconomic-related health inequality. The study aims to explore the potential causes of socioeconomic-related health inequality in urban and rural areas of China over the past two decades. METHODS: This study used six waves of the China Health and Nutrition Survey (CHNS) from 1991 to 2006. The recentered influence function (RIF) regression decomposition method was employed to decompose socioeconomic-related health inequality in China...
July 18, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28719881/perfluoroalkyl-acids-in-surface-waters-and-tapwater-in-the-qiantang-river-watershed-influences-from-paper-textile-and-leather-industries
#10
Guo-Hui Lu, Nan Gai, Peng Zhang, Hai-Tao Piao, Shu Chen, Xiao-Chun Wang, Xing-Chun Jiao, Xiao-Cai Yin, Ke-Yan Tan, Yong-Liang Yang
Perfluoroalkyl acids (PFAAs) are widely used as multi-purpose surfactants or water/oil repellents. In order to understand the contamination level and compositional profiles of PFAAs in aqueous environment in textile, leather, and paper making industrial areas, surface waters and tap waters were collected along the watershed of the Qiantang River where China's largest textile, leather, and paper making industrial bases are located. For comparison, surface water and tapwater samples were also collected in Hangzhou and its adjacent areas...
July 4, 2017: Chemosphere
https://www.readbyqxmd.com/read/28719359/levodopa-in-parkinson-s-disease-a-review-of-population-pharmacokinetics-pharmacodynamics-analysis
#11
Amélie Marsot, Romain Guilhaumou, Jean Philippe Azulay, Olivier Blin
BACKGROUND: Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer's disease. Although levodopa remains the single effective agent in the management of Parkinson's disease, the accurate determination of this optimal dosage is complicated by marked between-subject and between-occasion variability in this population.  This review presents a synthesis of the population pharmacokinetic and pharmacodynamic models of levodopa described in Parkinson's disease...
2017: Journal of Pharmacy & Pharmaceutical Sciences: a Publication of the Canadian Society for Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28718959/characterization-of-a-highly-al-3-selective-fluorescence-probe-based-on-naphthalimide-schiff-base-and-its-application-to-practical-water-samples
#12
Kesheng Shen, Shanshan Mao, Xinkui Shi, Fei Wang, Yuling Xu, Stephen Opeyemi Aderinto, Huilu Wu
A new fluorescent Al(3+) -probe, N-allyl-4-[3,3'-((2-aminoethyl)azanediyl)-bis(N´-(2-hydroxybenzylidene)propanehy-drazide)]-1,8-naphthalimide (L), was designed and synthesized based on 1,8-naphthalimide. The probe L contains 1,8-naphthalimide moiety as the fluorophore and a Schiff base as the recognition group. The structure of L was determined by single crystal X-ray. L emission at 526 nm increased on addition of Al(3+) under excitation wavelength at 350 nm. L exhibited high selectivity and sensitivity fluorescence emission towards to Al(3+) in ethanol/Tris-HCl buffer solution (1:1, v/v, pH = 7...
July 18, 2017: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/28718777/an-assembly-and-interaction-of-upconversion-and-plasmonic-nanoparticles-on-organometallic-nanofibers-enhanced-multicolor-upconversion-downshifting-emission-and-plasmonic-effect
#13
Priyam Singh, Praveen Kumar Shahi, Rajiv Prakash, S B Rai
We herein present a novel inorganic-organic hybrid nanoparticle (HNPs) constituted of inorganic NPs, NaY0.78Er0.02Yb0.2F4, and organometallic nanofiber, Tb(ASA)3Phen (TAP). The X-ray diffraction, Fourier transform infrared absorption and TEM analyse reveal that, the prepared ultrafine upconversion nanoparticles {UCNPs (6-9 nm)} are dispersed on the surface of TAP nanofibers. We observe that addition of TAP in UCNPs, effectively prevents the surface quenching to boost the UC intensity and enables tuning of UC emission from green to red region by controlling the phonon frequency around Er3+ ion...
July 18, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28717633/cementum-and-dentin-repair-following-root-damage-caused-by-the-insertion-of-self-tapping-and-self-drilling-miniscrews
#14
Majid Ghanbarzadeh, Farzin Heravi, Reihaneh Abrishamchi, Hooman Shafaee, Narges Ghazi, Parya Heravi, Hamid Ghanbarzadeh
OBJECTIVE: The aim of this study was to evaluate the histological responses of cementum, root dentin, and pulp following intentional root injuries caused via self-tapping and self-drilling miniscrews. MATERIALS AND METHODS: Fourteen patients (with a mean age of 15.7 years and age range of 14-18 years) who were scheduled for the extraction of all four first premolars as part of their orthodontic treatment plan participated in this study. The roots of the right and the left quadrants' first premolars were designedly injured using self-tapping miniscrews and self-drilling miniscrews, respectively...
July 2017: Journal of Orthodontic Science
https://www.readbyqxmd.com/read/28716743/low-level-exposure-to-manganese-from-drinking-water-and-cognition-in-school-age-children
#15
Maryse F Bouchard, Céline Surette, Pierre Cormier, Delphine Foucher
BACKGROUND: Manganese (Mn) is an element found in the environment and certain geographic areas have elevated concentrations in soil and water du to natural conditions or anthropic activities. A growing body of data suggests that exposure to manganese in drinking water could be neurotoxic. OBJECTIVE: Firstly, we aimed to examine the association between exposure to manganese from drinking water and cognition in children consuming well water. Secondly, we also aimed to examine the relation between cognition and manganese concentrations in children's hair, nail, and saliva...
July 14, 2017: Neurotoxicology
https://www.readbyqxmd.com/read/28716246/cognitive-impairment-predicts-worse-short-term-response-to-spinal-tap-test-in-normal-pressure-hydrocephalus
#16
Thomas Wolfsegger, Raffi Topakian
INTRODUCTION: In patients with idiopathic normal pressure hydrocephalus (iNPH), the spinal tap test (STT) is commonly used to predict ventriculoperitoneal shunt responsiveness. Clinical improvement following STT usually is measured by testing gait function. In our study, we investigated the impact of cognitive impairment on gait improvement after STT. METHODS: 22 patients with the clinical and radiological diagnosis of iNPH underwent gait analyses (mobile measuring system Medilogic) before and 2-4h after STT in self-paced gait velocity over 7m...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28715408/potential-risk-factors-associated-with-human-alveolar-echinococcosis-systematic-review-and-meta-analysis
#17
Franz J Conraths, Carolina Probst, Alessia Possenti, Belgees Boufana, Rosella Saulle, Giuseppe La Torre, Luca Busani, Adriano Casulli
BACKGROUND: Human alveolar echinococcosis (AE) is a severe zoonotic disease caused by the metacestode stage of Echinococcus multilocularis. AE is commonly associated with a long incubation period that may last for more than ten years. The objective of this systematic literature review was to identify and summarize the current knowledge on statistically relevant potential risk factors (PRFs) associated with AE in humans. METHODOLOGY/PRINCIPAL FINDINGS: Six bibliographic databases were searched, generating a total of 1,009 publications...
July 17, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28715056/evaluation-of-timing-of-re-appearance-of-vbnc-legionella-for-risk-assessment-in-hospital-water-distribution-systems
#18
L Marinelli, A Cottarelli, A G Solimini, A Del Cimmuto, M De Giusti
BACKGROUND: In this study we estimated the presence of Legionella species, viable but non-culturable (VBNC), in hospital water networks. We also evaluated the time and load of Legionella appearance in samples found negative using the standard culture method. METHODS: A total of 42 samples was obtained from the tap water of five hospital buildings. The samples were tested for Legionella by the standard culture method and were monitored for up to 12 months for the appearance of VBNC Legionella...
September 2017: Annali di Igiene: Medicina Preventiva e di Comunità
https://www.readbyqxmd.com/read/28714710/a-relative-bilingual-advantage-in-switching-with-preparation-nuanced-explorations-of-the-proposed-association-between-bilingualism-and-task-switching
#19
Alena Stasenko, Georg E Matt, Tamar H Gollan
Bilingual language switching may increase general switching efficiency, but the evidence on this question is mixed. We hypothesized that group differences in switching might be stronger at a long cue-target interval (CTI), which may better tap general switching abilities (Yehene & Meiran, 2007). Eighty Spanish-English bilinguals and 80 monolinguals completed a color-shape switching task, and an analogous language-switching task, varying CTI (short vs. long) in both tasks. With longer preparation time (long CTI), bilinguals exhibited significantly smaller task-switching costs than monolinguals, but only in the first half of trials...
July 17, 2017: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/28714493/handwashing-practices-in-neonatal-intensive-care-unit-paediatric-intensive-care-unit-and-neonatal-nurseries-in-patan-hospital
#20
S Joshi, P Amatya, B Poudel, S A Yadav
BACKGROUND: Hand hygiene has been identified as the single most important factor in minimising hospital acquired infections. However, compliance of handwashing guidelines has remained low. The aim of this study was to study the handwashing practices in the Paediatric and Neonatal intensive care units and Neonatal nurseries in Patan Hospital, and secondly to re-evaluate the improvement on compliance of handwashing guidelines after intervention. METHODS: Pre-intervention study was conducted by covertly observing the handwashing practices by the healthcare workers...
January 2017: Journal of Nepal Health Research Council
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