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Sumaya Rahman, Hatem Zayed
The GCC is an economic alliance of six Arab countries, including Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates (UAE). The rate of endogamous marriage among the GCC countries is approaching 100%, with very high consanguineous marriage rates. Although breast cancer is on the rise in the GCC countries, there are dearth of studies reporting on the genetic epidemiology of breast cancer. In this study, we investigated the frequency of BRCA1/2 and non-BRCA1/2 mutations in breast cancer patients in the GCC countries...
May 16, 2018: Gene
Nada Madi, Wassim Chehadeh, Mohammed Asadzadeh, Mariam Al-Turab, Anfal Al-Adwani
Respiratory syncytial virus (RSV) is the most frequently identified viral agent in infants, children, and elderly people with acute respiratory tract infections (ARTIs). This study is the only one of its kind in Kuwait, and its purpose was to investigate the genetic variability of the G protein gene in RSV strains prevalent in Kuwait. Respiratory samples were collected from patients with ARTIs in various hospitals in Kuwait and subjected to reverse transcription PCR (RT-PCR) amplifying a fragment of the G gene of RSV...
May 19, 2018: Archives of Virology
Mohammadreza Masjedi, Elaheh Ainy, Faried Zayeri, Rogayeh Paydar
OBJECTIVES: This study conducted in 2016 aimed to assess the prevalence and incidence of asthma and chronic obstructive pulmonary disease (COPD) in the Eastern Mediterranean Region (EMR). MATERIAL AND METHODS: A meta-analysis to evaluate the published research relating to asthma and COPD was conducted using data from 23 EMR Office (EMRO) countries and searching using the web of science, PubMed, SciVerse Scopus, Google scholar, and MEDLINE databases. The keywords entered were all EMRO countries (Afghanistan, Bahrain, Djibouti, Egypt, Islamic republic Iran, Iraq, Jordan, Kuwait, Lebanon, Libyan Arab Jamahiriya, Morocco, Oman, Pakistan, Palestine, Qatar, Saudi Arab, Somalia, Sudan, Syrian Arab Republic, Tunisia, the United Arab Emirates, Yemen republic, and Cyprus) and asthma OR chronic obstructive pulmonary disease (COPD) OR (chronic bronchitis)...
April 2018: Turkish Thoracic Journal
Hesham Tarraf, Omur Aydin, Dilsad Mungan, Mohammad Albader, Bassam Mahboub, Adam Doble, Aaicha Lahlou, Luqman Tariq, Fayaz Aziz, Abdelkader El Hasnaoui
BACKGROUND: Asthma is a common chronic respiratory disease leading to morbidity, mortality and impaired quality of life worldwide. Information on asthma prevalence in the Middle East is fragmented and relatively out-dated. The SNAPSHOT program was conducted to obtain updated information. METHODS: SNAPSHOT is a cross-sectional epidemiological program carried out in five Middle Eastern countries (Egypt, Turkey, Kuwait, Saudi Arabia, and the United Arab Emirates, the latter three grouped into a Gulf cluster) to collect data on asthma, allergic rhinitis, benign prostatic hyperplasia and bipolar disorder...
May 11, 2018: BMC Pulmonary Medicine
Ali H Ziyab, Adnan T Abul
OBJECTIVES: To examine trends in asthma hospitalisation and mortality rates from 2000 to 2014 in Kuwait according to sex, age and nationality. METHODS: For this nationwide, retrospective observational study, data from hospital discharge records and death certificates listing asthma as the primary reason for hospitalisation or mortality were obtained from the National Center for Health Information database using International Classification of Diseases, Tenth Revision codes J45 and J46...
May 8, 2018: BMJ Open
Zaid Sayedalamin, Taher Fawzy Halawa, Mukhtiar Baig, Osama Almutairi, Hassan Allam, Tahir Jameel, Zohair Jamil Gazzaz, Hazem Atta
OBJECTIVE: There is a lack of research-oriented physicians in several Arab countries and especially in Gulf region countries. In this context, it is important to explore medical students' perceptions and motivations towards research. The aim of the present study was to investigate research attitude, practices, and motivations among medical students from GCC countries. RESULTS: There were 228 students who participated in this study (male 88, females 140). Thirty-eight percent of the students were participating from Saudi Arabia, 20...
May 8, 2018: BMC Research Notes
Adekunle Adekile, Meaad Hassan, Akram Asbeutah, Mohamed Al-Hinai, Omar Trad, Nayef Farhan
OBJECTIVES: Transcranial Doppler ultrasound is used to identify patients with sickle cell disease (SCD) at risk for stroke. We performed transcranial Doppler studies in patients from 4 countries in the Arabian Peninsula (Kuwait, Oman, Iraq, and United Arab Emirates) to document the prevalence of abnormal transcranial Doppler findings. METHODS: The patients were recruited from outpatient clinics and studied in a steady state. Transcranial Doppler examinations were performed with standard equipment by experienced operators...
May 6, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Shaimaa F Hussein, Abdullah Almajran, Ahmed N Albatineh
AIMS: The purpose of this study is to estimate the prevalence of health literacy among patients with type II diabetes and investigate its association with several covariates. No studies were conducted in the Arabian Gulf region characterizing such factors for this population. METHODS: A cross sectional study was implemented in which 359 type II diabetes patients were recruited from diabetes centers across Kuwait. Health literacy was measured by STOFHLA. Multivariate linear regression was applied to investigate the relationship between health literacy and several covariates...
May 2, 2018: Diabetes Research and Clinical Practice
M U Beg, S A Butt, S Al-Dufaileej, Q Karam, T K Al-Sharrah, T Saeed
The health of a marine ecosystem can effectively be monitored by studying the levels of biomarkers in a representative species. A change in background level of a biomarker indicates exposure to a specific type of pollutants. It also identifies bioavailability and the organism response to the causative agent among the compounds present in the surrounding water body. Yellowfin seabream (Acanthopagrus latus), a local variety of fish, was examined for parent PAHs in the liver, its metabolites in bile by the GC-MS method as exposure biomarkers and cytochrome P4501A1 by assay of ethoxyresorufin-o-deethylase (EROD) in the liver as an effect biomarker...
May 4, 2018: Environmental Monitoring and Assessment
Mohamed H Elshahidi, Nada Y Monir, Mohamed A Elzhery, Ahmed A Sharaqi, Hames Haedaya, Basem I Awad, Khaled Zaghloul
Objective: To systematically search the literature and to summarize current evidence pertaining to the epidemiology of SCI in the MENA region incidence, gender, age, type of the injury and etiology of the injury. Methods: Embase, PubMed, Scopus, Web of Science and EBSCOhost were systematically searched from their dates of inception till July 2017 for English and non-English language articles. Also, regional databases were searched. Data were extracted from eligible articles and pooled under the random effect model using R ...
April 2018: Bulletin of Emergency and Trauma
Jasim Alabbad, Fawaz Abdul Raheem, Ahmad Almusaileem, Sulaiman Almusaileem, Saba Alsaddah, Abdulaziz Almubarak
Purpose: To investigate the reliability of medical student logbook data in assessing student performance and predicting outcomes in an objective standardized clinical exam and a multiplechoice exam during surgery rotation. In addition, we examined the relationship between exam performance and the number of clinical tutors per student. Materials and methods: A retrospective review of the logbooks of first and third clinical year medical students at the Faculty of Medicine, Kuwait University, was undertaken during their surgery rotation during the academic year 2012-2013...
2018: Advances in Medical Education and Practice
Wasmiya A Alhayyan, Sharat C Pan, Fawzi M AlQatami
INTRODUCTION: Cleft lip and palate (CLAP) are the most common craniofacial anomalies and birth defects globally. Despite the fact that a tertiary care registry of clefts has existed in Kuwait since 2008, to date there is no published data regarding the prevalence of orofacial clefts in this population. OBJECTIVE: To tabulate the pattern of orofacial clefts from tertiary care center registration during 2009 through 2014 and to estimate the prevalence and trend using population-based records...
January 1, 2018: Cleft Palate-craniofacial Journal
Dima Alkaed, Nadine Ibrahim, Fatima Ismail, Roula Barake
OBJECTIVE: To assess the validity and reliability of the Kuwait Adult Nutrition Knowledge Questionnaire (KANKQ) in adult students as an initial step to validation in the general adult population. METHODS: Participants (n = 253; aged ≥21 years) were categorized based on academic background and designated into groups known to differ in nutrition knowledge. Participants completed the questionnaire twice. Independent-samples t test, Pearson correlation coefficients, and Cronbach α were used to assess reliability and validity (P < ...
April 25, 2018: Journal of Nutrition Education and Behavior
Peter C Dworschak, Gary C B Poore
Re-examination of the holotype of Neoaxius nicoyaensis Sakai, 2017 showed that it is conspecific with the axiid Guyanacaris caespitosa Squires, 1979 and thus Neoaxius Sakai, 2017 and Neoaxiidae Sakai, 2017 are respectively subjective junior synonyms of Guyanacaris Sakai, 2011 and Axiidae Huxley, 1879. The types and numerous specimens of the callianassid Trypaea vilavelebita Sakai Türkay, 2012 are juveniles of the common northeastern Atlantic-Mediterranean species, Callianassa subterranea (Montagu, 1808); the name is therefore a subjective junior synonym...
March 12, 2018: Zootaxa
Turki Al-Said, S W A Naqvi, Faiza Al-Yamani, Alexandr Goncharov, Loreta Fernandes
Measurements of total organic carbon (TOC) for two years in Kuwaiti waters showed high TOC levels (101.0-318.4, mean 161.2 μM) with maximal concentrations occurring within the polluted Kuwait Bay and decreasing offshore, indicating substantial anthropogenic component. Analysis of winter-time data revealed a large increase in density over the past four decades due to decrease in Shatt Al-Arab runoff, implying that the dissolved/suspended organic matter in surface waters of the northern Gulf could be quickly injected into the Gulf Deep Water (GDW)...
April 2018: Marine Pollution Bulletin
Kother Nasser, Abu Salim Mustafa, Mohd Wasif Khan, Prashant Purohit, Inaam Al-Obaid, Rita Dhar, Wadha Al-Fouzan
Acinetobacter baumannii is an important opportunistic pathogen in global health care settings. Its dissemination and multidrug resistance pose an issue with treatment and outbreak control. Here, we present draft genome assemblies of six multidrug-resistant clinical strains of A. baumannii isolated from patients admitted to one of two major hospitals in Kuwait.
April 19, 2018: Genome Announcements
Hanan E Badr, Maha Al-Khaledi, Hussah Al-Dousari, Shaikhah Al-Dhufairi, Taiba Al-Mousawi, Rehab Al-Azemi, Farah Al-Azimi
OBJECTIVE: This study was aimed at assessing health-related quality of life (HRQOL) among adult patients with diabetes attending primary health care diabetes clinics in Kuwait and to examine the factors associated with patients with the HRQOL of patients with diabetes. METHODS: This cross-sectional study was conducted among 503 patients with diabetes attending 26 primary healthcare diabetes clinics in Kuwait. A self-administered questionnaire on participants' socio-demographic and clinical characteristics, in addition to the Diabetes Self-Management Questionnaire (DSMQ) to assess patients' DSM was used...
April 17, 2018: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
Samar S Boswihi, Edet E Udo, Stefan Monecke, Bindu Mathew, Bobby Noronha, Tina Verghese, Sajida B Tappa
BACKGROUND: Frequent changes in the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) occurring worldwide demand regular surveillance to study their composition and distribution in healthcare facilities. We investigated the genotypic characteristics of MRSA obtained in Kuwait hospitals to better understand their clonal distribution. MATERIALS AND METHODS: A total of 1,327 MRSA isolates obtained from clinical samples in 13 Kuwait hospitals from 1 January to 31 December 2016 were investigated using antibiogram, SCCmec typing, spa typing and DNA microarray...
2018: PloS One
Hosam M Zowawi, Melanie W Syrmis, Timothy J Kidd, Hanan H Balkhy, Timothy R Walsh, Sameera M Al Johani, Reem Y Al Jindan, Mubarak Alfaresi, Emad Ibrahim, Amina Al-Jardani, Jameela Al Salman, Ali A Dashti, Hanna E Sidjabat, Omar Baz, Ella Trembizki, David M Whiley, David L Paterson
PURPOSE: The molecular epidemiology and resistance mechanisms of carbapenem-resistant Pseudomonas aeruginosa (CRPA) were determined in hospitals in the countries of the Gulf Cooperation Council (GCC), namely, Saudi Arabia, the United Arab Emirates, Oman, Qatar, Bahrain and Kuwait. METHODOLOGY: Isolates were screened for common carbapenem-resistance genes by PCR. Relatedness between isolates was assessed using previously described genotyping methods: an informative-single nucleotide polymorphism MassARRAY iPLEX assay (iPLEX20SNP) and the enterobacterial repetitive intergenic consensus (ERIC)-PCR assay, with selected isolates being subjected to multilocus sequence typing (MLST)...
April 17, 2018: Journal of Medical Microbiology
Lara Nasreddine, Jennifer J Ayoub, Ayoub Al Jawaldeh
This situation analysis for the World Health Organization Eastern Mediterranean Region focuses on specific nutrition indicators, namely low birth weight, exclusive breastfeeding, under- and overnutrition (anthropometric indicators) and anaemia. The regional average prevalence of low birth weight and exclusive breastfeeding was estimated at 19.31% and 29.3%, respectively. Stunting, wasting and underweight had an average prevalence of 28%, 8.69% and 18%, respectively. Afghanistan, Djibouti, Pakistan, Sudan and Yemen had the highest burden of stunting (> 30%)...
April 5, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
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