Read by QxMD icon Read

lactate and training

Joanna Majerczak, Marcin Grandys, Krzysztof Duda, Agnieszka Zakrzewska, Aneta Balcerczyk, Leszek Kolodziejski, Dorota Szymoniak-Chochol, Ryszard T Smolenski, Grzegorz Bartosz, Stefan Chlopicki, Jerzy A Zoladz
In this study we have evaluated the effect of 20-weeks of moderate-intensity endurance training (ET) on the endothelial glycocalyx layer integrity in relation to the training-induced changes in antioxidant defence. Eleven healthy young, untrained men performed an incremental cycling exercise until exhaustion before and after 20 weeks of ET. Endurance training consisted of 40- minute sessions, mainly of moderate-intensity (∼50% of VO2max ), performed 4 times per week. Venous blood samples were taken at rest and at the end of the maximal exercise test...
October 17, 2016: Experimental Physiology
Cian McGinley, David John Bishop
This study measured the adaptive response to exercise training for each of the acid/base transport protein families, including providing isoform-specific evidence for the monocarboxylate transporter (MCT)1/4 chaperone protein basigin and for the electrogenic sodium/bicarbonate cotransporter (NBCe)1. We investigated whether 4 weeks of work-matched, high-intensity interval training (HIIT), performed either just above the lactate threshold (HIITΔ20; n = 8), or close to peak aerobic power (HIITΔ90; n = 8), influenced adaptations in acid/base transport protein abundance, non-bicarbonate muscle buffer capacity (βmin vitro), and exercise capacity in active men...
October 14, 2016: Journal of Applied Physiology
Xijun Liang, Lin Liu, Tingting Fu, Qian Zhou, Danxia Zhou, Liwei Xiao, Jing Liu, Yan Kong, Hui Xie, Fanchao Yi, Ling Lai, Rick B Vega, Daniel P Kelly, Steven R Smith, Zhenji Gan
Lactate dehydrogenase (LDH) catalyzes the interconversion of pyruvate and lactate, which are critical fuel metabolites of skeletal muscle particularly during exercise. However, the physiological relevance of LDH remains poorly understood. Here we show that Ldhb expression is induced by exercise in human muscle and negatively correlated with changes in intramuscular pH levels, a marker of lactate production, during isometric exercise. We found that the expression of Ldhb is regulated by exercise-induced peroxisome proliferator-activated receptor-g coactivator 1α (PGC-1α)...
October 13, 2016: Journal of Biological Chemistry
Shaun K Morris, Lisa G Pell, Mohammed Ziaur Rahman, Michelle C Dimitris, Abdullah Mahmud, M Munirul Islam, Tahmeed Ahmed, Eleanor Pullenayegum, Tahmid Kashem, Shaila S Shanta, Jonathan Gubbay, Eszter Papp, Michelle Science, Stanley Zlotkin, Daniel E Roth
BACKGROUND: Early infancy is a high-risk period for severe acute respiratory infection (ARI), particularly in low-income countries with resource-limited health systems. Lower respiratory tract infection (LRTI) is commonly preceded by upper respiratory infection (URTI), and often caused by respiratory syncytial virus (RSV), influenza and other common community-acquired viral pathogens. Vitamin D status is a candidate modifiable early-life determinant of the host antiviral immune response and thus may influence the risk of ARI-associated morbidity in high-risk populations...
October 13, 2016: BMC Pregnancy and Childbirth
Vicente Javier Clemente-Suárez, José Juan Robles-Pérez, Jesús Fernández-Lucas
Parachute jump is an extreme activity that elicits an intense stress response that affects jumpers' body systems being able to put them at risk. The present research analysed modifications in blood oxygen saturation (BOS), heart rate (HR), cortisol, glucose, lactate, creatine kinase (CK), muscles strength, cortical arousal, autonomic modulation, pistol magazine reload time (PMRT) and state anxiety before and after an automatic open parachute jump in 38 male Spanish soldiers (25.6 ± 5.9 years). A MANOVA with samples as a fixed factor and Effect Size (ES) were conducted...
October 11, 2016: Journal of Sports Sciences
Michael J Duncan, Neil D Clarke, Martin Cox, Mike Smith
In many sport and exercise situations, cognitive performance is required under conditions of high physiological load and high cognitive anxiety. However, few studies have assessed all these components in situ. The current study sought to address this issue. Fourteen adults (9 males, 5 females) completed 2 incremental exercise trials (perceived competition or perceived practice) in a counterbalanced order. Cognitive performance, via a test of visual discrimination, rating of perceived exertion (RPE), heart rate (HR), blood lactate (Bla), and anxiety scores, was recorded at rest, 70% [Formula: see text] and 90% [Formula: see text]...
October 8, 2016: Journal of Sports Sciences
Brandon A Baiamonte, Robert R Kraemer, Chelsea N Chabreck, Matthew L Reynolds, Kayla M McCaleb, Georgia L Shaheen, Daniel B Hollander
Previous research has demonstrated significant decreases in pain perception in healthy individuals following both aerobic and upper body resistance exercise, but research on circuit training has been limited. The purpose of the study was to determine the effects of a strenuous bout of dynamic circuit resistance exercise on pain threshold and pain tolerance in conjunction with changes in blood lactate levels, heart rate (HR), and perceived exertion. A sample of 24 college-age students participated in 2 sessions: (1) a maximal strength testing session and (2) a circuit training bout of exercise that consisted of 3 sets of 12 repetitions with a 1:1 work to rest ratio at 60% one-repetition maximum (1-RM) predicted from a three-repetition maximum (3-RM) for 9 exercises...
October 7, 2016: Journal of Sports Sciences
Alex J Wadley, Ida S Svendsen, Michael Gleeson
Altitude exposure can exaggerate the transient increase in markers of oxidative stress observed following acute exercise. However, these responses have not been monitored in endurance-trained cyclists at altitudes typically experienced whilst training. Endurance trained males (n=12; mean (±SD) age: 28 ± 4 years, V̇O2max 63.7 ± 5.3 ml/kg/min) undertook two 75-min exercise trials at 70% relative V̇O2max; once in normoxia and once in hypobaric hypoxia, equivalent to 2000m above sea level (hypoxia). Blood samples were collected before, immediately after and 2 h post-exercise to assess plasma parameters of oxidative stress (protein carbonylation (PC), thiobarbituric acid reactive substances (TBARS), total antioxidant capacity (TAC) and catalase activity (CAT))...
October 6, 2016: International Journal of Sport Nutrition and Exercise Metabolism
F Javier Núñez, Luis J Suarez-Arrones, Paul Cater, Alberto Mendez-Villanueva
The aim of this study was to examine the kinematics and kinetics (force, velocity and acceleration) and blood lactate concentration of the Versapulley (VP) device in comparison with free weight (FW) exercise at a similar external load. Fifteen rugby players randomly performed two training sessions of 6 sets of 6 repetitions with 20 s of recovery in between sets of the high pull exercise with the VP and the FW. Both training sessions were separated by 72 h. Barbell displacement (cm.), peak velocity (m/s), peak acceleration (m/s(2)), mean propulsive velocity (m/s), mean propulsive acceleration (m/s(2)), propulsive phase (%), mean and maximal force (Newtons) were continuously recorded during each repetition...
September 6, 2016: International Journal of Sports Physiology and Performance
Benoit Capostagno, Michael I Lambert, Robert P Lamberts
Finding the optimal balance between high training loads and recovery is a constant challenge for cyclists and their coaches. Monitoring improvements in performance and levels of fatigue is recommended to correctly adjust training to ensure optimal adaptation. However, many performance tests require a maximal or exhaustive effort, which reduces their real-world application. The purpose of this review was to investigate the development and use of submaximal cycling tests that can be used to predict and monitor cycling performance and training status...
September 2016: International Journal of Sports Physiology and Performance
Takuro Tobina, Yukari Mori, Yukiko Doi, Fuki Nakayama, Akira Kiyonaga, Hiroaki Tanaka
Muscle peroxisome proliferator-activated receptor gamma co-activator 1 (PGC-1)α gene expression is influenced by the Gly482Ser gene polymorphism, which is a candidate genetic risk factor for diabetes mellitus and obesity. This study investigated the effects of PGC-1 gene Gly482Ser polymorphisms on alterations in glucose and lipid metabolism induced by exercise training. A 12-week intervention study was performed for 119 participants who were more than 65 years of age and completed exercise training at lactate threshold intensity...
October 3, 2016: Journal of Physiological Sciences: JPS
Björn Gerdle, Malin Ernberg, Kaisa Mannerkorpi, Britt Larsson, Eva Kosek, Nikolaos Christidis, Bijar Ghafouri
BACKGROUND: Fibromyalgia syndrome (FMS) is associated with central alterations, but controversies exist regarding the presence and role of peripheral factors. Microdialysis (MD) can be used in vivo to study muscle alterations in FMS. Furthermore for chronic pain conditions such as FMS, the mechanisms for the positive effects of exercise are unclear. This study investigates the interstitial concentrations of algesics and metabolites in the vastus lateralis muscle of 29 women with FMS and 28 healthy women before and after an exercise intervention...
2016: PloS One
Karla M Greco, Bianca M Conti, Cynthia J Bucci, Samuel M Galvagno
STUDY OBJECTIVE: To determine risk factors associated with reintubations in adult patients with soft tissue infections. DESIGN: A retrospective case-control design. SETTING: Operating room and postoperative recovery area. PATIENTS: There were 39 patients who presented for surgical intervention of their soft tissue infection and 222 controls having general surgery who were matched for age, sex, and body mass index. All patients were older than the age of 18 years and mostly American Society of Anesthesiologists physical status of III to IV and presented to our level 1 trauma center...
November 2016: Journal of Clinical Anesthesia
B Schmitz, L Thorwesten, M Lenders, T Duning, J Stypmann, E Brand, S-M Brand
The aim of this study was to assess the extent of exercise intolerance in Fabry disease (FD) patients and to report individual effects of physical exercise. Exercise capacity and strength of 14 patients (mean age 46 years, 6 females) were determined using cycle ergometry and isokinetic measurements. Patients performed a strength/circuit exercise training protocol for 12 months. The mean relative maximum performance of the group was low at baseline and increased by 12.1% (baseline: 1.9 [0.9-3.4] W·kg(-1) vs...
September 27, 2016: International Journal of Sports Medicine
Morten Hostrup, Jens Bangsbo
Mechanisms underlying fatigue development and limitations for performance during intense exercise have been intensively studied during the past couple of decades. Fatigue development may involve several interacting factors and depends on type of exercise undertaken and training level of the individual. Intense exercise (½-6 min) causes major ionic perturbations (Ca(2+) , Cl(-) , H(+) , K(+) , lactate(-) , and Na(+) ) that may reduce sarcolemmal excitability, Ca(2+) release, and force production of skeletal muscle...
September 27, 2016: Journal of Physiology
Terri Susan Graham-Paulson, Thomas Andrew William Paulson, Claudio Perret, Keith Tolfrey, Philip Cordery, Victoria Louise Goosey-Tolfrey
PURPOSE: To investigate the absorption curve and acute effects of caffeine at rest in individuals with no spinal cord injury (SCI), paraplegia (PARA) and tetraplegia (TETRA). METHODS: Twenty-four healthy males (8 able-bodied (AB), 8 PARA and 8 TETRA) consumed 3 mg[BULLET OPERATOR]kg caffeine anhydrous (CAF) in a fasted state. Plasma caffeine [CAF], glucose, lactate, free-fatty acid [FFA] and catecholamine concentrations were measured during a 150 min rest period...
September 23, 2016: Medicine and Science in Sports and Exercise
Andrea Váncsa
Using current recommended treatment, a majority of patients with idiopathic inflammatory myopathy develop muscle impairment and poor health. Beneficial effects of exercise have been reported on muscle performance, aerobic capacity and health in chronic polymyositis and dermatomyositis, as well as in active disease and inclusion body myositis to some extent. Importantly, randomized controlled trials indicate that improved health and decreased clinical disease activity could be mediated through increased aerobic capacity...
September 2016: Orvosi Hetilap
Brendan R Scott, Katie M Slattery, Dean V Sculley, Catriona Lockhart, Ben J Dascombe
This study assessed whether hypoxia augments anabolic responses to moderate-load resistance exercise. Fourteen trained males performed moderate-load resistance exercise in normoxia (NORM; fraction of inspired oxygen [FIO2] = 21%) and moderate-level hypoxia (MH; FIO2 = 16%). Exercise comprised 3 sets of 10 repetitions of squats and deadlifts at 60% of 1-repetition maximum, with 60 s inter-set rest. Blood lactate (BLa) was quantified after each exercise, while arterial oxygen saturation (SpO2) and heart rate (HR) were assessed following each set...
September 20, 2016: Journal of Strength and Conditioning Research
Abraão Tiago Batista Guimarães, Raíssa de Oliveira Ferreira, Letícia Martins Rabelo, Bianca Costa E Silva, Joyce Moreira de Souza, Wellington Alves Mizael da Silva, Ivandilson Pessoa Pinto de Menezes, Aline Sueli de Lima Rodrigues, Boniek Gontijo Vaz, Denys Ribeiro de Oliveira Costa, Igor Pereira, Anderson Rodrigo da Silva, Guilherme Malafaia
The main aim of the present paper is to assess whether the parental generation exposure to such discharges could cause object recognition deficits in their offspring. Male and female C57Bl/6J mice were put to mate after they were exposed to 7.5% and 15% tannery effluents or water (control group), for 60 days. The male mice were withdrawn from the boxes after 15 days and the female mice remained exposed to the treatment during the gestation and lactation periods. The offspring were subjected to the object recognition test after weaning in order to assess possible cognition losses...
December 2016: Chemosphere
Júlio César Camargo Alves, Cecília Segabinazi Peserico, Geraldo Angelo Nogueira, Fabiana Andrade Machado
Few studies verified the reliability of the lactate threshold determined by Dmax method (LTDmax) in runners and it remains unclear the effect of the regression model and the final speed on the reliability of LTDmax. This study aimed to examine the test-retest reliability of the speed at LTDmax in runners, considering the effects of the regression models (exponential-plus-constant vs third-order polynomial) and final speed criteria (complete vs proportional). Seventeen male, recreational runners performed 2 identical incremental exercise tests, with increments of 1 km·h(-1) each for 3 min on treadmill to determine peak treadmill speed (Vpeak) and lactate threshold...
October 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"