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https://www.readbyqxmd.com/read/28106247/validation-of-the-nccn-ipi-for-diffuse-large-b-cell-lymphoma-dlbcl-the-addition-of-%C3%AE-2-microglobulin-yields-a-more-accurate-geltamo-ipi
#1
Carlos Montalbán, Antonio Díaz-López, Ivan Dlouhy, Jordina Rovira, Armando Lopez-Guillermo, Sara Alonso, Alejandro Martín, Juan M Sancho, Olga García, Jose M Sánchez, Mario Rodríguez, Silvana Novelli, Antonio Salar, Antonio Gutiérrez, Maria J Rodríguez-Salazar, Mariana Bastos, Juan F Domínguez, Rubén Fernández, Sonia Gonzalez de Villambrosia, José A Queizan, Raul Córdoba, Raquel de Oña, Andrés López-Hernandez, Julian M Freue, Heidys Garrote, Lourdes López, Ana M Martin-Moreno, Jose Rodriguez, Víctor Abraira, Juan F García
The study included 1848 diffuse large B-cell lymphoma (DLBCL)patients treated with chemotherapy/rituximab. The aims were to validate the National Comprehensive Cancer Network International Prognostic Index (NCCN-IPI) and explore the effect of adding high Beta-2 microglobulin (β2M), primary extranodal presentation and intense treatment to the NCCN-IPI variables in order to develop an improved index. Comparing survival curves, NCCN-IPI discriminated better than IPI, separating four risk groups with 5-year overall survival rates of 93%, 83%, 67% and 49%, but failing to identify a true high-risk population...
January 20, 2017: British Journal of Haematology
https://www.readbyqxmd.com/read/28095075/a-pilot-study-using-entropy-as-a-non-invasive-assessment-of-running
#2
Andrew M Murray, Joong Hyun Ryu, John Sproule, Anthony P Turner, Phil Graham-Smith, Marco Cardinale
PURPOSE: Running performance is influenced by the interaction of biomechanical and physiological factors. Miniaturised accelerometers worn by the athlete can be used to quantify mechanical aspects of running and be used as a non-invasive tool to assess training status and progression. The aim of this study was to define and validate a method to assess running regularity and allow the estimation of an individual's V̇O2 and/or blood lactate [La]b based on data collected with accelerometers and heart rate (HR)...
January 17, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28095061/methods-of-monitoring-training-load-and-their-relationships-to-changes-in-fitness-and-performance-in-competitive-road-cyclists
#3
Dajo Sanders, Grant Abt, Matthijs K Hesselink, Tony Myers, Ibrahim Akubat
PURPOSE: The aim of this study was to assess the dose-response relationships between different training load methods and aerobic fitness and performance in competitive road cyclists. METHOD: Training data from 15 well-trained competitive cyclists were collected during a 10-week (December - March) pre-season training period. Before and after the training period, participants underwent a laboratory incremental exercise test with gas exchange and lactate measures and a performance assessment using an 8-min time trial (8MT)...
January 17, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28094489/the-sex-specific-internal-and-external-demands-imposed-on-players-during-ultimate-frisbee-game-play
#4
Maria C Madueno, Crystal O Kean, Aaron T Scanlan
BACKGROUND: Despite the growing popularity of Ultimate Frisbee (UF) across sexes, the game demands imposed on players have been predominately examined in males. This study aimed to compare the internal and external demands of UF game-play in males and females. METHODS: Male (N = 10) and female (N = 10) recreational UF players competed in separate sex-specific, indoor UF games. Internal responses (blood lactate concentration ([BLa-]), rating of perceived exertion (RPE), and heart rate (HR)) and external responses (direction-specific and total relative (·min-1) PlayerLoadTM (PL), and Estimated Equivalent Distance (EED)) were measured...
January 17, 2017: Journal of Sports Medicine and Physical Fitness
https://www.readbyqxmd.com/read/28090141/do-maximal-aerobic-power-and-blood-lactate-concentration-affect-specific-judo-fitness-test-performance-in-female-judo-athletes
#5
H Garbouj, M A Selmi, R Haj Sassi, M Haj Yahmed, K Chamari, A Chaouachi
The Special Judo Fitness Test (SJFT) has become the test most widely used by coaches and physical trainers for assessment of competitors' judo-specific physical aptitude and training programme prescription. The aim of this study was to investigate the relationship between the SJFT performance indices and both maximal aerobic power and the level of blood lactate concentrations in female judo athletes. Seventeen female judokas (age: 21.9±1.6 years, body mass: 74.6±27.4 kg, height: 164.5±8.6 cm; BMI: 27.1±8...
December 2016: Biology of Sport
https://www.readbyqxmd.com/read/28081033/performance-aspects-and-physiological-responses-in-male-amateur-boxing-competitions-a-brief-review
#6
Maamer Slimani, Helmi Chaabène, Philip Davis, Emerson Franchini, Karim Chamari
Boxing is one of the most popular striking combat sports in the world. The aim of this review was to present data concerning performance analysis (time-motion and technical/tactical analysis) and physiological responses (i.e., blood lactate concentration [BLC], heart rate and/or oxygen consumption) during novice and elite male simulated and official amateur boxing competitions in any age category. The present review shows that boxing competition is a high-intensity intermittent striking combat sport. Typically, the activity-to-rest ratio was higher in elite (18:1) than novice (9:1) boxers and significant differences were observed between rounds (1 round=16:1, 2 round=8:1, and 3 round=6:1) in novice boxers...
January 4, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28076352/high-intensity-interval-training-elicits-higher-enjoyment-than-moderate-intensity-continuous-exercise
#7
Jacob S Thum, Gregory Parsons, Taylor Whittle, Todd A Astorino
: Exercise adherence is affected by factors including perceptions of enjoyment, time availability, and intrinsic motivation. Approximately 50% of individuals withdraw from an exercise program within the first 6 mo of initiation, citing lack of time as a main influence. Time efficient exercise such as high intensity interval training (HIIT) may provide an alternative to moderate intensity continuous exercise (MICT) to elicit substantial health benefits. This study examined differences in enjoyment, affect, and perceived exertion between MICT and HIIT...
2017: PloS One
https://www.readbyqxmd.com/read/28066938/effect-of-gender-and-exercise-on-haematological-and-biochemical-parameters-in-holsteiner-horses
#8
A Andriichuk, H Tkachenko
The objective of this study was to assess the influence of exercise of average intensity in the haematological and biochemical values, as well as acidic resistance of erythrocytes in mares and stallions of Holsteiner breed. A total of seventeen horses of Holstein breed (seven mares and 10 stallions aged 6 years) were used in this study. The blood samples were assessed for haematocrit (HCT) value, haemoglobin concentration (HGB), the amount of red blood cells (RBC), white blood cells (WBC), platelets (PLT), leucogram, mean corpuscular haemoglobin concentration (MCHC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), red cell distribution width (RDW) and platelet distribution width (PDW)...
January 8, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28051345/how-does-interval-training-prescription-impact-physiological-and-perceptual-responses
#9
Stephen Seiler, Øystein Sylta
The purpose of this study was to compare physiological responses and perceived exertion among well trained cyclists (n=63) performing three different high intensity interval training (HIIT) prescriptions differing in work bout duration and accumulated duration, but all prescribed with maximal session effort. Data are presented as mean(Standard Deviation). Subjects (male, 38(8) y, VO2peak 62(6) mL.kg(-1) min(-1)) completed up to 24 HIIT sessions over 12 weeks as part of a training intervention study. Sessions were prescribed as 4x16 min, 4x8 min, or 4x4 min with 2 min recovery periods (8 sessions of each prescription, balanced over time)...
January 4, 2017: International Journal of Sports Physiology and Performance
https://www.readbyqxmd.com/read/28033123/accuracy-of-a-modified-lactate-minimum-test-and-reverse-lactate-threshold-test-to-determine-maximal-lactate-steady-state
#10
Patrick Wahl, Christian Manunzio, Florian Vogt, Sarah Strütt, Prisca Volmary, Wilhelm Bloch, Joachim Mester
This study evaluated the accuracy of a modified-lactate-minimum-test (mLMT), a modified-reverse-lactate-threshold-test (mRLT), in comparison to two established threshold concepts (OBLA & mDmax) to determine power output at maximal-lactate-steady-state (MLSS) in cycling. Nineteen subjects performed an mLMT, an mRLT, a graded-exercise-test (100W start, +20W every 3 min) and 3 or more constant-load tests of 30 minutes to determine power output at MLSS. The mLMT and mRLT both consisted of an initial lactate priming-segment, followed by a short recovery phase...
December 20, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28031762/effects-of-fatigue-on-throwing-performance-in-experienced-team-handball-players
#11
Alberto Nuño, Ignacio J Chirosa, Roland van den Tillaar, Rafael Guisado, Ignacio Martín, Isidoro Martinez, Luis J Chirosa
The purpose of this study was to investigate the effect of central and peripheral physiological fatigue on throwing accuracy and ball release velocity in team handball. Twenty male subjects (age 24.7 ± 3.9 yrs, body mass 88.5 ± 5.0 kg, body height 1.86 ± 0.05 m, training experience 12.7 ± 3.8 yrs) from one handball team participated in this study. The participants completed four sets of eight laps of a circuit that consisted of specific team handball drills/exercises, with decreasing recovery times between the laps in each set in order to induce physiological fatigue...
December 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28030366/nicu-nurses-and-lactation-based-support-and-care
#12
Elizabeth Froh, Katherine Dahlmeier, Diane L Spatz
BACKGROUND: The provision of human milk and breastfeeding is essential in the neonatal intensive care unit (NICU) population. However, recent national research has demonstrated very low percentages of NICU nurses providing lactation-based support and care to patients and families, and less than half of all NICUs have an International Board Certified Lactation Consultant (IBCLC) on staff. PURPOSE: The purpose of this study was to describe how NICU bedside nurses are providing lactation-based support and care during their shifts and the frequency of that support...
December 27, 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
https://www.readbyqxmd.com/read/28025642/short-duration-small-sided-football-and-to-a-lesser-extent-whole-body-vibration-exercise-induce-acute-changes-in-markers-of-bone-turnover
#13
RANDOMIZED CONTROLLED TRIAL
J L Bowtell, S R Jackman, S Scott, L J Connolly, M Mohr, G Ermidis, R Julian, F Yousefian, E W Helge, N R Jørgensen, J Fulford, K M Knapp, P Krustrup
We aimed to study whether short-duration vibration exercise or football sessions of two different durations acutely changed plasma markers of bone turnover and muscle strain. Inactive premenopausal women (n = 56) were randomized to complete a single bout of short (FG15) or long duration (FG60) small sided football or low magnitude whole body vibration training (VIB). Procollagen type 1 amino-terminal propeptide (P1NP) was increased during exercise for FG15 (51.6 ± 23.0 to 56.5 ± 22.5 μg·L(-1), mean ± SD, P < 0...
2016: BioMed Research International
https://www.readbyqxmd.com/read/28018241/master-athletes-are-extending-the-limits-of-human-endurance
#14
REVIEW
Romuald Lepers, Paul J Stapley
The increased participation of master athletes (i.e., >40 years old) in endurance and ultra-endurance events (>6 h duration) over the past few decades has been accompanied by an improvement in their performances at a much faster rate than their younger counterparts. Aging does however result in a decrease in overall endurance performance. Such age-related declines in performance depend upon the modes of locomotion, event duration, and gender of the participant. For example, smaller age-related declines in cycling performance than in running and swimming have been documented...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/28013058/leg-compressions-improve-ventilatory-efficiency-while-reducing-peak-and-post-exercise-blood-lactate-but-does-not-improve-perceived-exertion-exercise-economy-or-aerobic-exercise-capacity-in-endurance-trained-runners
#15
Eric Rivas, John D Smith, Nestor W Sherman
PURPOSE: The objective of this study was to determine if leg compressions would alter cardiorespiratory and perceived exertion measures during rest, submaximal and maximal exercise in endurance-trained runners. METHOD: Thirteen young, endurance trained runners (10 males, 20.9±3y, 58.9±5.7mlkgmin(-1)) completed a randomized design, leg compressions and non-compression control condition. The incremental graded exercise test consisted of baseline rest and submaximal intensities at 23%, 70%, 75%, 85% and then a progressive increase to 100% VO2max...
December 21, 2016: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28010810/conventional-and-novel-body-temperature-measurement-during-rest-and-exercise-induced-hyperthermia
#16
Colin Towey, Chris Easton, Robert Simpson, Charles Pedlar
Despite technological advances in thermal sensory equipment, few core temperature (TCORE) measurement techniques have met the established validity criteria in exercise science. Additionally, there is debate as to what method serves as the most practically viable, yet upholds the proposed measurement accuracy. This study assessed the accuracy of current and novel TCORE measurement techniques in comparison to rectal temperature (TREC) as a reference standard. Fifteen well-trained subjects (11 male, 4 female) completed 60min of exercise at an intensity equating to the lactate threshold; measured via a discontinuous exercise test...
January 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28009784/brief-intense-stair-climbing-improves-cardiorespiratory-fitness
#17
Mary K Allison, Jessica H Baglole, Brian J Martin, Martin J MacInnis, Brendon J Gurd, Martin J Gibala
PURPOSE: Sprint interval training (SIT) is a time-efficient strategy to improve cardiorespiratory fitness (CRF); however, most protocols have been studied in laboratory settings and require specialized equipment. We investigated the efficacy of brief intense stair climbing as a practical model of SIT to improve CRF. METHODS: Two separate studies, each consisting of an acute and chronic phase, were conducted in a total of 31 sedentary women (age=24±10 y; BMI=23±4 kg•m)...
December 22, 2016: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28002177/selected-physiological-perceptual-and-physical-performance-changes-during-two-bouts-of-prolonged-high-intensity-intermittent-running-separated-by-72-hours
#18
Nicholas Dobbin, Kevin Lamb, Craig Twist
This study investigated the effects of performing a second 90-minute intermittent running protocol 72 hours after an initial trial on selected physiological, perceptual and sprint running measures. Eight sub-elite soccer players provided measures of isokinetic muscle function, counter-movement jump (CMJ), 10 m sprinting, and muscle soreness before, and at 0, 24, 48 and 72 h after a 90-minute intermittent high intensity running bout (IHIR 1). A second 90-minute intermittent high intensity running bout (IHIR 2) was performed 72 h after the first...
December 8, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28000342/a-new-model-of-short-acceleration-based-training-improves-exercise-performance-in-old-mice
#19
R Niel, M Ayachi, L Mille-Hamard, L Le Moyec, P Savarin, M-J Clement, S Besse, T Launay, V L Billat, I Momken
In order to identify a more appealing exercise strategy for the elderly, we studied a mouse model to determine whether a less time-consuming training program would improve exercise performance, enzyme activities, mitochondrial respiration, and metabolomic parameters. We compared the effects of short-session (acceleration-based) training with those of long-session endurance training in 23-month-old mice. The short-session training consisted of five acceleration-based treadmill running sessions over 2 weeks (the acceleration group), whereas the endurance training consisted of five-one-hour treadmill sessions per week for 4 weeks (the endurance group)...
December 20, 2016: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/27968847/bushenjianpi-formula-combined-with-entecavir-for-hbeag-negative-chronic-hepatitis-b-patients-a-multicentre-randomised-double-blind-placebo-controlled-trial
#20
Yue-Qiu Gao, Xin Zhang, Man Li, Zhen-Hua Zhou, Xue-Hua Sun, Xiao-Jun Zhu, Shu-Gen Jin
BACKGROUND: The treatment combination of traditional Chinese medicine with western medicine results in significant decrease of serum hepatitis B virus (HBV) DNA and increase of HBeAg loss in patients with HBeAg-positive chronic hepatitis B (CHB) without any serious adverse events. We aimed to assess whether the Bushenjianpi Formula combined with entecavir could increase the HBsAg loss rate in patients with HBeAg-negative CHB. METHODS: In this multicentre, randomised, double-blind, placebo-controlled trial, we recruited patients with HBeAg-negative CHB from ten third-level grade-A hospital of Traditional Chinese Medicine...
October 2016: Lancet
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