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https://www.readbyqxmd.com/read/28938456/growth-hormone-improves-cardiopulmonary-capacity-and-body-composition-in-children-with-growth-hormone-deficiency
#1
Donatella Capalbo, Flavia Barbieri, Nicola Improda, Francesco Giallauria, Elisa Di Pietro, Antonio Rapacciuolo, Raffaella Di Mase, Carlo Vigorito, Mariacarolina Salerno
Context: Growth hormone deficiency (GHD) in children may be associated with early cardiovascular risk factors and alterations in left ventricular (LV) structure and function; however, data on cardiopulmonary functional capacity are lacking. Objectives: Aim of the study was to evaluate the effect of GHD and GH therapy on cardiopulmonary functional capacity, left and right cardiac structure and function, and body composition in children and adolescents. Design: Prospective, case-control study...
August 29, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28937309/metabolic-and-hormonal-responses-to-different-resistance-training-systems-in-elderly-men
#2
Marcos R Paunksnis, Alexandre L Evangelista, Cauê V La Scala Teixeira, Gustavo Alegretti João, Rafael M Pitta, Angelica C Alonso, Aylton Figueira, Andrey Jorge Serra, Julien S Baker, Brad Jon Schoenfeld, Danilo S Bocalini
OBJECTIVE: To compare acute and sub-acute responses in hormonal profile and metabolic parameters in elderly people who participated in two methods of strength training (ST) with equalized loads. METHODS AND MATERIALS: A total of 12 elder individuals (65 ± 3 years) were randomly assigned to two training methods: constant intensity (CI, 3 sets of 10 repetitions with 75% of 1RM) and variable intensity (VI, 1st set: 12 repetitions at 67% of 1RM > 2nd set: 10 repetitions at 75% of 1RM and 3rd set: 8 repetitions at 80% of 1RM)...
September 22, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28934819/the-role-of-gut-hormones-in-diet-induced-weight-change-a-systematic-review
#3
Xue Zhao, Qing Han, Xiaokun Gang, You Lv, Yujia Liu, Chenglin Sun, Guixia Wang
Gut hormones are known to play an important role in long-term weight loss maintenance after bariatric surgery. However, the interplay between gut hormones and diet-induced weight changes remains unclear. Our aims were to evaluate the alterations of gut hormones in diet-induced weight loss, weight maintenance, and weight regain periods. Available studies were searched on MEDLINE, EMASE, ClinicalTrials.gov, the Cochrane Library, and Web of science from inception to October 2016. After selection, 16 studies with 656 participants were included...
September 21, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28934816/vigorous-physical-activity-is-associated-with-regular-aerobic-exercise-induced-increased-serum-testosterone-levels-in-overweight-obese-men
#4
Hiroshi Kumagai, Toru Yoshikawa, Asako Zempo-Miyaki, Kanae Myoenzono, Takehiko Tsujimoto, Kiyoji Tanaka, Seiji Maeda
Testosterone is a male sex hormone and low circulating testosterone levels are associated with various health disorders in men. Obesity results in reduced circulating testosterone levels in men. Previously, we demonstrated that lifestyle modifications (combination of aerobic exercise and dietary modification) increase circulating testosterone levels in overweight/obese men. However, the effect of regular aerobic exercise on serum testosterone levels remains unclear. The purpose of this study was to investigate the effect of a 12-week aerobic exercise intervention on circulating testosterone levels in normal-weight and overweight/obese men...
September 21, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/28931917/exercise-training-enhances-in-vivo-clearance-of-endotoxin-and-attenuates-inflammatory-responses-by-potentiating-kupffer-cell-phagocytosis
#5
Shoichi Komine, Kentaro Akiyama, Eiji Warabi, Sechang Oh, Keisuke Kuga, Kazunori Ishige, Shinji Togashi, Toru Yanagawa, Junichi Shoda
The failure of Kupffer cells (KCs) to remove endotoxin is an important factor in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). In this study, the effects of exercise training on KC function were studied in terms of in vivo endotoxin clearance and inflammatory responses. Mice were allocated into rest and exercise groups. KC bead phagocytic capacity and plasma steroid hormone levels were determined following exercise training. Endotoxin and inflammatory cytokine levels in plasma were determined over time following endotoxin injection...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28931543/the-effects-of-intravenous-low-dose-dopamine-infusion-on-glucose-regulation-during-prolonged-aerobic-exercise
#6
Blair D Johnson, Ana B Peinado, Sushant M Ranadive, Timothy B Curry, Michael J Joyner
The carotid body chemoreceptors are activated during hypoglycemia and contribute to glucoregulation during prolonged exercise in dogs. Low dose intravenous infusions of dopamine have been shown to blunt the activation of the carotid body chemoreceptors during hypoxia. Therefore, we tested the hypotheses that dopamine would blunt glucoregulatory responses and attenuate plasma glucose during prolonged aerobic exercise in healthy participants. Twelve healthy participants completed two randomized exercise sessions at 65% peak oxygen consumption for up to 120 minutes...
September 20, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28925889/physical-activity-does-it-really-increase-bone-density-in-postmenopausal-women-a-review-of-articles-published-between-2001-2016
#7
Daria Segev, Devora Hellerstein, Ayelet Dunsky
BACKGROUND: Physical activity is known for its many health benefits, among them the positive effect on bone health during the life cycle. During childhood, physical stress stimulates bone remodeling and increases density. However, due to hormonal changes during adulthood, and mainly during postmenopause the rate of bone remodeling is slowed and is less efficient. As a result, argument has arisen in the literature regarding the benefit or harm of physical activity on bone health among postmenopausal women...
September 18, 2017: Current Aging Science
https://www.readbyqxmd.com/read/28915538/long-term-t3-and-t4-treatment-as-an-alternative-to-aerobic-exercise-training-in-improving-cardiac-function-post-myocardial-infarction
#8
Rayane Brinck Teixeira, Alexsandra Zimmer, Alexandre Luz de Castro, Bruna Gazzi de Lima-Seolin, Patrick Türck, Rafaela Siqueira, Adriane Belló-Klein, Pawan K Singal, Alex Sander da Rosa Araujo
Here we aimed to compare the beneficial effects of T3 and T4 hormone treatment to those provided by aerobic exercise training in Wistar rats post-myocardial infarction (MI). Rats in one group were SHAM-operated and in the other group were subjected to MI surgery. One week after surgery, the MI group animals either received T3 and T4 hormones by gavage or underwent a low intensity aerobic exercise training protocol on a treadmill, and both treatments lasted until 10 weeks after MI. Untreated SHAM-operated and MI groups were also followed for the same duration...
September 11, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28912012/the-effects-of-aerobic-exercise-on-depression-like-anxiety-like-and-cognition-like-behaviours-over-the-healthy-adult-lifespan-of-c57bl-6-mice
#9
Julie A Morgan, Gaurav Singhal, Frances Corrigan, Emily J Jaehne, Magdalene C Jawahar, Bernhard T Baune
Preclinical studies have demonstrated exercise improves various types of behaviours such as anxiety-like, depression-like, and cognition-like behaviours. However, these findings were largely conducted in studies utilising short-term exercise protocols, and the effects of lifetime exercise on these behaviours remain unknown. This study investigates the behavioural effects of lifetime exercise in normal healthy aging C57BL/6 mice over the adult lifespan. 12 week-old C57BL/6 mice were randomly assigned to voluntary wheel running or non-exercise (control) groups...
September 11, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28911998/establishing-age-specific-reference-intervals-for-anti-m%C3%A3-llerian-hormone-in-adult-chinese-women-based-on-a-multicenter-population
#10
Xinqi Cheng, Qiong Zhang, Min Liu, Shijun Li, Zhihua Tao, Kiyoshi Ichihara, Songlin Yu, Kai Zhang, Pengchang Li, Jianhua Han, Ling Qiu
AIM OF THIS STUDY: Anti-Müllerian hormone (AMH) is useful for the assessment of ovarian reserve and treatment of individualized in vitro fertilization (IVF). The aim of this study is to establish AMH reference interval for adult Chinese women on the Beckman Beckman DxI 800 platform. MATERIAL AND METHODS: From May to September 2013, serum from 1169 apparently healthy adult females from five representative cities in China (Beijing, Hangzhou, Guangzhou, Dalian and Urumqi) were collected, and AMH was analyzed on the platform of Beckman DxI 800 automated chemiluminescence immunoassay...
September 12, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28911142/deficient-endogenous-glucose-production-during-exercise-after-total-pancreatectomy-islet-autotransplantation
#11
Lindsey D Bogachus, Elizabeth Oseid, Melena Bellin, Adrian Vella, R Paul Robertson
Context: Total pancreatectomy followed by intrahepatic islet autotransplantation (TP/IAT) is performed to alleviate severe, unrelenting abdominal pain caused by chronic pancreatitis, to improve quality of life, and to prevent diabetes. Objective: To determine the cause of exercise-induced hypoglycemia that is a common complaint in TP/IAT recipients. Design: Participants completed 1 hour of steady-state exercise. Setting: Hospital research unit...
September 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28899903/socs3-expression-in-sf1-cells-regulates-adrenal-differentiation-and-exercise-performance
#12
João Ab Pedroso, Pedro Omori Ribeiro de Mendonça, Marco As Fortes, Igor Tomaz, Vitor L Pecorali, Thais B Auricino, Ismael C Costa, Leandro B Lima, Isadora C Furigo, Debora N Bueno, Angela M Ramos-Lobo, Claudimara Ferini Pacicco Lotfi, Jose Donato
Many hormones/cytokines are secreted in response to exercise and cytokine signaling may play a pivotal role in the training adaptations. To investigate the importance of cytokine signaling during vertical ladder climbing, a resistance exercise model, we produced mice lacking SOCS3 protein exclusively in steroidogenic factor-1 (SF1) cells (SF1 Socs3 KO mice). SF1 expression is found in steroidogenic cells of the adrenal cortex and gonads, as well as in neurons of the ventromedial nucleus of the hypothalamus...
September 12, 2017: Journal of Endocrinology
https://www.readbyqxmd.com/read/28889225/effects-of-blood-flow-restriction-during-moderate-intensity-eccentric-knee-extensions
#13
Michael Behringer, Lars Heinke, Jannik Leyendecker, Joachim Mester
We investigated if blood flow restriction (BFR, cuff pressure 20 mmHG below individual occlusion pressure) increases metabolic stress, hormonal response, release of muscle damage markers, and muscle swelling induced by moderate-intensity eccentric contractions. In a randomized, matched-pair design, 20 male subjects (25.3 ± 3.3 years) performed four sets of unilateral eccentric knee extensions (75% 1RM) to volitional failure with (IG) or without (CG) femoral BFR. Despite significant differences of performed repetitions between IG (85...
September 9, 2017: Journal of Physiological Sciences: JPS
https://www.readbyqxmd.com/read/28887324/exercise-induced-catecholamines-activate-the-hippo-tumor-suppressor-pathway-to-reduce-risks-of-breast-cancer-development
#14
Christine Dethlefsen, Louise S Hansen, Christian Lillelund, Christina Andersen, Julie Gehl, Jesper F Christensen, Bente K Pedersen, Pernille Hojman
Strong epidemiologic evidence documents the protective effect of physical activity on breast cancer risk, recurrence, and mortality, but the underlying mechanisms remain to be identified. Using human exercise-conditioned serum for breast cancer cell incubation studies and murine exercise interventions, we aimed to identify exercise factors and signaling pathways involved in the exercise-dependent suppression of breast cancer. Exercise-conditioned serum from both women with breast cancer (n = 20) and healthy women (n = 7) decreased MCF-7 (hormone-sensitive) and MDA-MB-231 (hormone-insensitive) breast cancer cell viability in vitro by 11% to 19% and reduced tumorigenesis by 50% when preincubated MCF-7 breast cancer cells were inoculated into NMRI-Foxn1(nu) mice...
September 8, 2017: Cancer Research
https://www.readbyqxmd.com/read/28886822/osteopenia-and-osteoporosis-in-female-athletes
#15
REVIEW
John M MacKnight
Disorders of bone density are especially prevalent among athletic women. The severity of bone loss ranges from osteopenia to frank osteoporosis. In female athletes, a higher incidence of osteoporosis is due to a decreased rate of bone accretion in youth, often as a result of hormonal deficiency and/or excessive exercise. Low bone mass poses a particular challenge for athletes because it predisposes to stress-related bone injuries and increases the risk of osteoporosis and insufficiency fractures with aging...
October 2017: Clinics in Sports Medicine
https://www.readbyqxmd.com/read/28886819/nutritional-aspects-of-the-female-athlete
#16
REVIEW
Kelly A Rossi
Athletes have specific needs based on sex, size, sport, exercise intensity, duration of activity, phase of training, and the season in which the sport is played. Nutritionally, the female athlete is unique, with needs that may vary based on hormonal fluctuations related to the menstrual cycle. This article provides an overview of the distinct nutritional needs and concerns of the physically active female, including energy availability, macronutrient needs, micronutrient needs, hydration, supplements, and other nutritional issues...
October 2017: Clinics in Sports Medicine
https://www.readbyqxmd.com/read/28884865/physical-training-improves-visceral-adipose-tissue-health-by-remodelling-extracellular-matrix-in-rats-with-estrogen-absence-a-gene-expression-analysis
#17
Fernanda O Duarte, Camila do Valle Gomes-Gatto, Jorge C Oishi, Anderson Diogo de S Lino, Uliana S Stotzer, Maria Fernanda C Rodrigues, Guilherme H Gatti da Silva, Heloisa S Selistre-de-Araújo
Adipose tissue development is associated with modifications involving extracellular matrix remodelling, and metalloproteinases play a significant role in this process. Reduced circulating sexual hormones cause impacts on the size, morphology and functions of the adipose tissue, increasing susceptibility to diseases. This study investigated whether exercise training may be an alternative strategy to combat the effects promoted by estrogen decay through modulation in gene expression patterns in the extracellular matrix (ECM) of visceral adipose tissue of ovariectomized rats...
September 8, 2017: International Journal of Experimental Pathology
https://www.readbyqxmd.com/read/28875825/study-of-irisin-hormone-level-in-type-2-diabetic-patients-and-patients-with-diabetic-nephropathy
#18
Salah Shelbaya, Manal Mohamed Abushady, Merhan Samy Nasr, Meram Mohamed Bekhet, Yasmine Abd-Al Mageed, Magdy Abbas
BACKGROUND: Type 2 diabetic patients with diabetic nephropathy are associated with multifactorial abnormal energy metabolism. Irisin has been recently introduced as a hormone that is exercise induced and is secreted by skeletal muscles. It is hypothesized that patients with chronic kidney disease usually have abnormal irisin levels. AIM: We aimed to study the level of Irisin hormone in patients with type 2 diabetes and to document if it is related to diabetic nephropathy...
August 29, 2017: Current Diabetes Reviews
https://www.readbyqxmd.com/read/28873320/influence-of-rhodiola-rosea-on-the-heat-acclimation-process-in-young-healthy-men
#19
Saima Timpmann, Anthony C Hackney, Maria Tamm, Kairi Kreegipuu, Eve Unt, Vahur Ööpik
The adaptogen <i>Rhodiola rosea</i> (RR) may mitigate stress responses and have beneficial effects on endurance capacity (EC) and mental performance. Heat acclimation (HA) improves EC in the heat, but the potential impact of RR on the HA process is unknown. Therefore, our intent was to determine would RR impact positively on the efficacy of the HA process. Twenty male subjects (age 22.5 ± 3.0 years) completed two EC tests involving walking (6 km·h <sup>-1</sup>) until volitional exhaustion in a climate chamber (air temperature, 42°C; relative humidity, 18%) before (H1) and after (H2) an 8-day HA period...
September 5, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28872400/what-is-the-most-effective-training-approach-for-preventing-noncontact-acl-injuries-in-high-school-aged-female-athletes
#20
Erica M Willadsen, Andrea B Zahn, Chris J Durall
CLINICAL SCENARIO: The high prevalence of noncontact anterior cruciate ligament (ACL) injuries in adolescent female athletes is thought to originate from hormonal, neuromuscular, and structural differences between sexes.(1) Although hormonal and structural factors are non-modifiable, neuromuscular control can be altered with training. A variety of training approaches have been adopted in ACL prevention programs including neuromuscular control training, core stability training, balance training, and plyometric exercise...
September 5, 2017: Journal of Sport Rehabilitation
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