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hormonal and exercise

Zhaowei Kong, Shengyan Sun, Min Liu, Qingde Shi
This study was to determine the effects of five-week high-intensity interval training (HIIT) on cardiorespiratory fitness, body composition, blood glucose, and relevant systemic hormones when compared to moderate-intensity continuous training (MICT) in overweight and obese young women. Methods. Eighteen subjects completed 20 sessions of HIIT or MICT for five weeks. HIIT involved 60 × 8 s cycling at ~90% of peak oxygen consumption ([Formula: see text]) interspersed with 12 s recovery, whereas MICT involved 40-minute continuous cycling at 65% of [Formula: see text]...
2016: Journal of Diabetes Research
Wen-Chyuan Chen, Yi-Ming Chen, Chi-Chang Huang, Yen-Dun Tzeng
Dehydroepiandrosterone (DHEA), the most abundant sex steroid, is primarily secreted by the adrenal gland and a precursor hormone used by athletes for performance enhancement. Whole-body vibration (WBV) is a well-known light-resistance exercise by automatic adaptations to rapid and repeated oscillations from a vibrating platform, which is also a simple and convenient exercise for older adults. However, the potential effects of DHEA supplementation combined with WBV training on to body composition, exercise performance, and hormone regulation are currently unclear...
2016: International Journal of Medical Sciences
Ross Beaumont, Philip Cordery, Mark Funnell, Stephen Mears, Lewis James, Phillip Watson
This study examined effects of 4 weeks of caffeine supplementation on endurance performance. Eighteen low-habitual caffeine consumers (<75 mg · day(-1)) were randomly assigned to ingest caffeine (1.5-3.0 mg · kg(-1)day(-1); titrated) or placebo for 28 days. Groups were matched for age, body mass, V̇O2peak and Wmax (P > 0.05). Before supplementation, all participants completed one V̇O2peak test, one practice trial and 2 experimental trials (acute 3 mg · kg(-1) caffeine [precaf] and placebo [testpla])...
October 20, 2016: Journal of Sports Sciences
Hye Jin Kim, Hae Min Yoon, Oran Kwon, Won Jun Lee
PURPOSE: Pueraria lobata/rehmannia glutinosa (PR) and exercise have been receiving a lot of attention from postmenopausal women, as a result of the side effects of estrogen replacement therapy. However, the effects of PR and exercise on fatty acid transporters (FATPs), which play essential role in fatty acid transport, have not been studied. In this study, we evaluated the effects of PR and aerobic exercise on FATP1, FABPpm and FAT/CD36 expression in ovariectomized rat skeletal muscles...
September 2016: Journal of Exercise Nutrition & Biochemistry
Liz Gough, Lindy M Castell, Rosalba Gatti, Richard J Godfrey
BACKGROUND: Growth hormone (GH) has many direct and indirect actions and roles including substrate regulation and priming of some cells of the immune system, and the expected aspects of growth and repair. Different concentrations in human body fluids reflect the exercise-induced growth hormone response (EIGR) after exercise. In populations such as elite athletes, the invasive nature of venous sampling is poorly accepted. Thus, this study examines possible viable alternatives such as urine and saliva samples and the GH concentration...
December 2016: Sports Medicine—Open
P Cordery, N Peirce, R J Maughan, P Watson
Catecholamine reuptake inhibition improves the performance of male volunteers exercising in warm conditions, but sex differences in thermoregulation, circulating hormones, and central neurotransmission may alter this response. With local ethics committee approval, nine physically active women (mean ± SD age 21 ± 2 years; height 1.68 ± 0.08 m; body mass 64.1 ± 6.0 kg; VO2peak 51 ± 7 mL/kg/min) were recruited to examine the effect of pre-exercise administration of Bupropion (BUP; 4 × 150 mg) on prolonged exercise performance in a warm environment...
October 13, 2016: Scandinavian Journal of Medicine & Science in Sports
Abdulkerim Kasim Baltaci, Rasim Mogulkoc, Mustafa Akil, Mursel Bicer
Selenium (Se), which is commonly found in nature, is one of the essential trace elements necessary for the normal development of human and animal organisms. Selenium was first defined in 1818 by the Swedish chemist Berzelius in sulfuric acid residues. At the end of 1960s, the role of selenium in human health began to attract attention and human diseases that resembled animal diseases responding to selenium was started to be investigated. Selenium, which is highly important for human health, is necessary for a variety of metabolic processes, including thyroid hormone metabolism, protection against oxidative stress and immunity functions...
September 2016: Pakistan Journal of Pharmaceutical Sciences
Carlos A Camillo, Christian R Osadnik, Hans van Remoortel, Chris Burtin, Wim Janssens, Thierry Troosters
The aim of this review was to identify the effectiveness of therapies added on to conventional exercise training to maximise exercise capacity in patients with chronic obstructive pulmonary disease (COPD). Electronic databases were searched, identifying trials comparing exercise training with exercise training plus "add-on" therapy. Outcomes included peak oxygen uptake (V'O2peak), work rate and incremental/endurance cycle and field walking tests. Individual trial effects on exercise capacity were extracted and collated into eight subgroups and pooled for meta-analysis...
January 2016: ERJ Open Research
M Schönfelder, H Hofmann, T Schulz, T Engl, D Kemper, B Mayr, C Rautenberg, R Oberhoffer, D Thieme
Administration of low amounts of endogenous hormones - so called micro-dosages - are supposed to represent a major challenge in doping analysis. To model such a situation, we have studied transdermal administrations of 2.4 mg/24 h testosterone patches and examined various steroid concentrations in blood, urine and saliva of 11 volunteers. Multiple samples were collected at t = 0, 3, 6, 9, 24, 48 and 72 h in four different phases, i.e. all combinations with/without physical exercise and with/without testosterone...
October 10, 2016: Drug Testing and Analysis
Ludovic Giloteaux, Maureen R Hanson, Betsy A Keller
BACKGROUND Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) present with profound fatigue, flu-like symptoms, pain, cognitive impairment, orthostatic intolerance, and post-exertional malaise (PEM), and exacerbation of some or all of the baseline symptoms. CASE REPORT We report on a pair of 34-year-old monozygotic twins discordant for ME/CFS, with WELL, the non-affected twin, and ILL, the affected twin. Both twins performed a two-day cardiopulmonary exercise test (CPET), pre- and post-exercise blood samples were drawn, and both provided stool samples for biochemical and molecular analysis...
October 10, 2016: American Journal of Case Reports
Tom J Hazell, Hashim Islam, Jillian R Hallworth, Jennifer L Copeland
Exercise-induced changes in appetite-regulating hormones may be intensity-dependent, however a clear dose-response relationship has not been established. The purpose of this study was to examine changes in anorexigenic markers (total PYY and GLP-1) in response to rest or exercise at submaximal and supramaximal intensities. Ten active males completed four experimental sessions in randomized order: 1) Moderate intensity continuous training (MICT; 30 min cycling at 65% VO2max); 2) High intensity continuous training (HICT; 30 min cycling at 85% VO2max); 3) Sprint interval training (SIT; 6 × 30 s "all-out" cycling bouts with 4 min recovery periods); 4) Control (CTRL; no exercise)...
October 6, 2016: Appetite
Magdalena Krajewska-Włodarczyk
The clinical picture of rheumatoid arthritis covers the condition of chronic inflammation connected to the increased concentration of inflammatory mediators, reduced physical activity, immobilization caused by pain, stiffness and joint destruction as well as accompanying hormonal and metabolic disorders. It all may lead to extra-articular complications, also to the loss of muscle mass with the weakness of muscle strength, adding to the disability and significantly lowering the patients' quality of life. Sarcopenia is an advanced form of muscle mass loss which constitutes an independent and vital threat for dexterity...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
Valéria Leme Gonçalves Panissa, Ursula Ferreira Julio, Felipe Hardt, Carolina Kurashima, Fábio Santos Lira, Monica Yuri Takito, Emerson Franchini
The aim of this study was to compare the effects of exercise intensity on appetite control: relative energy intake (energy intake minus the energy expenditure of exercise; REI), hunger scores, and appetite-regulating hormones in men and women. Eleven men and 9 women were submitted to 4 experimental sessions: high-intensity intermittent all-out exercise (HIIE-A) for 60 × 8 s interspersed by 12 s of passive recovery; high-intensity intermittent exercise (HIIE) at 100% of maximal load attained in incremental test; steady-state exercise at 60% of maximal load, matched by work done; and a control session...
July 7, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Nadine Taleb, Ali Emami, Corinne Suppere, Virginie Messier, Laurent Legault, Martin Ladouceur, Jean-Louis Chiasson, Ahmad Haidar, Rémi Rabasa-Lhoret
AIMS/HYPOTHESIS: The aim of this study was to assess whether the dual-hormone (insulin and glucagon) artificial pancreas reduces hypoglycaemia compared with the single-hormone (insulin alone) artificial pancreas during two types of exercise. METHODS: An open-label randomised crossover study comparing both systems in 17 adults with type 1 diabetes (age, 37.2 ± 13.6 years; HbA1c, 8.0 ± 1.0% [63.9 ± 10.2 mmol/mol]) during two exercise types on an ergocycle and matched for energy expenditure: continuous (60% [Formula: see text] for 60 min) and interval (2 min alternating periods at 85% and 50% [Formula: see text] for 40 min, with two 10 min periods at 45% [Formula: see text] at the start and end of the session)...
October 4, 2016: Diabetologia
Bianca C Bernardo, Julie R McMullen
Exercise-induced cardiac remodeling is typically an adaptive response associated with cardiac myocyte hypertrophy and renewal, increased cardiac myocyte contractility, sarcomeric remodeling, cell survival, metabolic and mitochondrial adaptations, electrical remodeling, and angiogenesis. Initiating stimuli/triggers of cardiac remodeling include increased hemodynamic load, increased sympathetic activity, and the release of hormones and growth factors. Prolonged and strenuous exercise may lead to maladaptive exercise-induced cardiac remodeling including cardiac dysfunction and arrhythmia...
November 2016: Cardiology Clinics
Catherine Napier, Earn H Gan, Simon H S Pearce
Loperamide is the most commonly used antidiarrhoeal medication in the UK. We report a serious and hitherto undocumented adverse effect of chronic use in a 45-year-old man with inflammatory bowel disease. He presented to the endocrine clinic with fatigue and low libido; biochemical assessment revealed hypogonadism and adrenal insufficiency without any elevated adrenocorticotropic hormone. When symptoms allowed, loperamide was reduced and a short synacthen test (SST) showed a 'clear pass' with a normal peak cortisol of 833 nmol/L...
2016: BMJ Case Reports
William B Horton, Jose S Subauste
CONTEXT: Type 1 diabetes mellitus (T1DM) results from a highly specific immune-mediated destruction of pancreatic β cells, resulting in chronic hyperglycemia. For many years, one of the mainstays of therapy for patients with T1DM has been exercise balanced with appropriate medications and medical nutrition. Compared to healthy peers, athletes with T1DM experience nearly all the same health-related benefits from exercise. Despite these benefits, effective management of the T1DM athlete is a constant challenge due to various concerns such as the increased risk of hypoglycemia...
April 2016: International Journal of Endocrinology and Metabolism
Julie M Hughes, Nisha Charkoudian, Jill N Barnes, Barbara J Morgan
Traditional exercise programs seem to be less osteogenic in the mature and post-mature skeleton compared to the young skeleton. This is likely because of the decline in sensitivity of bone to mechanical loading that occurs with advancing age. Another factor contributing to the apparently diminished benefit of exercise in older adults is failure of widely used measurement techniques (i.e., DXA) to identify changes in 3-dimensional bone structure, which are important determinants of bone strength. Moreover, although hormonal contributors to bone loss in the elderly are well-recognized, the influence of age-related increases in sympathetic nervous system activity, which impacts bone metabolism, is rarely considered...
2016: Frontiers in Physiology
Mohamed Ali Hammami, Abderraouf Ben Abderrahman, Anthony C Hackney, Wiem Kebsi, Adam L Owen, Amar Nebigh, Ghazi Racil, Zouhair Tabka, Hassane Zouhal
The aim of this study was to investigate the effects of two soccer-training seasons on physical fitness and hormone concentrations in elite youth soccer players. Twenty male elite soccer players (SP, age 14.5 ± 0.4 years) and 20 male control subjects (CS, age 14.3 ± 0.3years) participated to the study. Anthropometric measurements, aerobic (Yo-Yo Intermittent Recovery Test Level 1 (YYIRT1)) and anaerobic soccer relevant performances (jump and sprint tests), blood testosterone (T), cortisol (C),sex hormone binding globulin (SHBG) and T/C ratio were assessed 5 times (from T0 to T4) during two competitive seasons...
September 23, 2016: Journal of Strength and Conditioning Research
H Brochard, C Boudebesse, C Henry, O Godin, M Leboyer, B Étain
OBJECTIVE: To examine the pathophysiologic mechanisms that may link circadian disorder and metabolic syndrome in bipolar disorder (BP). METHOD: A systematic review of the literature was conducted from January 2013 to January 2015, using the Medline and Cochrane databases, using the keywords "metabolic syndrome", "obesity", "leptin" and "circadian disorders", "sleeping disorders" and cross-referencing them with "bipolar disorder". The following types of publications were candidates for review: (i) clinical trials; (ii) studies involving patients diagnosed with bipolar disorder; (iii) studies involving patients with sleeping disorder; or (iv) data about metabolic syndrome...
September 20, 2016: L'Encéphale
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