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https://www.readbyqxmd.com/read/27932989/hypoxic-living-and-exercise-training-alter-adipose-tissue-leptin-leptin-receptor-in-rats
#1
Yingli Lu, Lianshi Feng, Minhao Xie, Li Zhang, Jianfang Xu, Zihong He, Tongjian You
Background: Hypobaric hypoxia results in weight loss in obese individuals, and exercise training is advocated for the treatment of obesity and its related metabolic dysfunctions. The purpose of this study was to investigate the effects of hypoxic living and exercise training on obesity and adipose tissue leptin/leptin receptor in dietary-induced obese rats. Methods: One hundred and thirty high-fat diet fed Sprague-Dawley rats were assigned into one of the following groups (n = 10 each): control, sedentary hypoxic living for 1-4 weeks (SH1, SH2, SH3, and SH4), living, and exercise training in normoxic conditions for 1-4 weeks (TN1, TN2, TN3, and TN4), and living and exercise training in hypoxic conditions for 1-4 weeks (TN1, TN2, TN3, and TN4)...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27923417/mechanisms-of-memory-dysfunction-during-high-altitude-hypoxia-training-in-military-aircrew
#2
Daniel A Nation, Mark W Bondi, Ellis Gayles, Dean C Delis
OBJECTIVES: Cognitive dysfunction from high altitude exposure is a major cause of civilian and military air disasters. Pilot training improves recognition of the early symptoms of altitude exposure so that countermeasures may be taken before loss of consciousness. Little is known regarding the nature of cognitive impairments manifesting within this critical window when life-saving measures may still be taken. Prior studies evaluating cognition during high altitude simulation have predominantly focused on measures of reaction time and other basic attention or motor processes...
December 7, 2016: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/27906593/does-swimming-at-a-moderate-altitude-favor-a-lower-oxidative-stress-in-an-intensity-dependent-manner-role-of-nonenzymatic-antioxidants
#3
Rafael A Casuso, Jerónimo Aragón-Vela, Gracia López-Contreras, Silvana N Gomes, Cristina Casals, Yaira Barranco-Ruiz, Jordi J Mercadé, Jesus R Huertas
Casuso, Rafael A., Jerónimo Aragón-Vela, Gracia López-Contreras, Silvana N. Gomes, Cristina Casals, Yaira Barranco-Ruiz, Jordi J. Mercadé, and Jesus R. Huertas. Does swimming at a moderate altitude favor a lower oxidative stress in an intensity-dependent manner? Role of nonenzymatic antioxidants. High-Alt Med Biol. 00:000-000, 2016-we aimed to describe oxidative damage and enzymatic and nonenzymatic antioxidant responses to swimming at different intensities in hypoxia. We recruited 12 highly experienced swimmers who have been involved in competitive swimming for at least 9 years...
December 1, 2016: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/27820657/prevalence-of-and-risk-factors-for-trachoma-in-oromia-regional-state-of-ethiopia-results-of-79-population-based-prevalence-surveys-conducted-with-the-global-trachoma-mapping-project
#4
Berhanu Bero, Colin Macleod, Wondu Alemayehu, Solomon Gadisa, Ahmed Abajobir, Yilikal Adamu, Menbere Alemu, Liknaw Adamu, Michael Dejene, Addis Mekasha, Zelalem Habtamu Jemal, Damtew Yadeta, Oumer Shafi, Genet Kiflu, Rebecca Willis, Rebecca M Flueckiger, Brian K Chu, Alexandre L Pavluck, Anthony W Solomon
PURPOSE: To complete the baseline trachoma map in Oromia, Ethiopia, by determining prevalences of trichiasis and trachomatous inflammation - follicular (TF) at evaluation unit (EU) level, covering all districts (woredas) without current prevalence data or active control programs, and to identify factors associated with disease. METHODS: Using standardized methodologies and training developed for the Global Trachoma Mapping Project, we conducted cross-sectional community-based surveys from December 2012 to July 2014...
November 7, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27779956/emergency-medical-considerations-in-a-space-suited-patient
#5
Alejandro Garbino, Derek M Nusbaum, Daniel M Buckland, Anil S Menon, Jonathan B Clark, Erik L Antonsen
The Stratex Project is a high altitude balloon flight that culminated in a freefall from 41,422 m (135,890 ft), breaking the record for the highest freefall to date. Crew recovery operations required an innovative approach due to the unique nature of the event as well as the equipment involved. The parachutist donned a custom space suit similar to a NASA Extravehicular Mobility Unit (EMU), with life support system mounted to the front and a parachute on the back. This space suit had a metal structure around the torso, which, in conjunction with the parachute and life support assembly, created a significant barrier to extraction from the suit in the event of a medical emergency...
2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/27766103/development-of-prediction-model-and-experimental-validation-in-predicting-the-curcumin-content-of-turmeric-curcuma-longa-l
#6
Abdul Akbar, Ananya Kuanar, Raj K Joshi, I S Sandeep, Sujata Mohanty, Pradeep K Naik, Antaryami Mishra, Sanghamitra Nayak
The drug yielding potential of turmeric (Curcuma longa L.) is largely due to the presence of phyto-constituent 'curcumin.' Curcumin has been found to possess a myriad of therapeutic activities ranging from anti-inflammatory to neuroprotective. Lack of requisite high curcumin containing genotypes and variation in the curcumin content of turmeric at different agro climatic regions are the major stumbling blocks in commercial production of turmeric. Curcumin content of turmeric is greatly influenced by environmental factors...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27750391/clarification-on-altitude-training
#7
Grégoire P Millet, Franck Brocherie, Raphael Faiss, Olivier Girard
The authors report that many LHTL studies in normobaric hypoxia (NH) "failed to show a positive outcome", which in our view is only partially true. In a cross-over design, we (Saugy et al. 2016) recently tested if LHTL in hypobaric hypoxia (HH) would lead to larger performance enhancement than in NH. Our hypothesis was that HH (i.e. natural altitude) would lead to larger enhancement than NH but the results were contrary to this hypothesis. So we cannot support the affirmation by Lundby & Robach that "natural altitude remains the best approach"...
October 17, 2016: Experimental Physiology
https://www.readbyqxmd.com/read/27667380/cardiovascular-effects-of-altitude-on-performance-athletes
#8
Ankit B Shah, Neil Coplan
Altitude plays an important role in cardiovascular performance and training for athletes. Whether it is mountaineers, skiers, or sea-level athletes trying to gain an edge by training or living at increased altitude, there are many potential benefits and harms of such endeavors. Echocardiographic studies done on athletes at increased altitude have shown evidence for right ventricular dysfunction and pulmonary hypertension, but no change in left ventricular ejection fraction. In addition, 10% of athletes are susceptible to pulmonary hypertension and high-altitude pulmonary edema...
2016: Reviews in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27622961/yoga-practice-improves-physiological-and-biochemical-status-at-high-altitudes-a-prospective-case-control-study
#9
Gidugu Himashree, Latika Mohan, Yogesh Singh
UNLABELLED: Context • High altitude (HA) is a psychophysiological stressor for natives of lower altitudes. Reducing the morbidity and optimizing the performance of individuals deployed in an HA region has been attempted and reported with varied results. Objective • The present study intended to explore the effects of comprehensive yogic practices on the health and performance of Indian soldiers deployed at HAs. Design • The research team designed a prospective, randomized, case-control study...
September 2016: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/27583364/exercise-induced-hypoxaemia-developed-at-sea-level-influences-responses-to-exercise-at-moderate-altitude
#10
Anne-Fleur Gaston, Fabienne Durand, Emma Roca, Grégory Doucende, Ilona Hapkova, Enric Subirats
PURPOSE: The aim of this study was to investigate the impact of exercise-induced hypoxaemia (EIH) developed at sea-level on exercise responses at moderate acute altitude. METHODS: Twenty three subjects divided in three groups of individuals: highly trained with EIH (n = 7); highly trained without EIH (n = 8) and untrained participants (n = 8) performed two maximal incremental tests at sea-level and at 2,150 m. Haemoglobin O2 saturation (SpO2), heart rate, oxygen uptake (VO2) and several ventilatory parameters were measured continuously during the tests...
2016: PloS One
https://www.readbyqxmd.com/read/27553127/dietary-nitrate-supplementation-enhances-high-intensity-running-performance-in-moderate-normobaric-hypoxia-independent-of-aerobic-fitness
#11
Oliver Michael Shannon, Lauren Duckworth, Matthew John Barlow, David Woods, Jose Lara, Mario Siervo, John Paul O'Hara
Nitrate-rich beetroot juice (BRJ) increases plasma nitrite concentrations, lowers the oxygen cost (V⋅O2) of steady-state exercise and improves exercise performance in sedentary and moderately-trained, but rarely in well-trained individuals exercising at sea-level. BRJ supplementation may be more effective in a hypoxic environment, where the reduction of nitrite into nitric oxide (NO) is potentiated, such that well-trained and less well-trained individuals may derive a similar ergogenic effect. We conducted a randomised, counterbalanced, double-blind placebo controlled trial to determine the effects of BRJ on treadmill running performance in moderate normobaric hypoxia (equivalent to 2500 m altitude) in participants with a range of aerobic fitness levels...
September 30, 2016: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/27467760/the-effect-of-an-altitude-training-camp-on-swimming-start-time-and-loaded-squat-jump-performance
#12
Amador García-Ramos, Igor Štirn, Paulino Padial, Javier Argüelles-Cienfuegos, Blanca De la Fuente, Carmen Calderón, Juan Bonitch-Góngora, Katja Tomazin, Boro Strumbelj, Vojko Strojnik, Belén Feriche
This study evaluated the influence of an altitude training (AT) camp on swimming start time and loaded squat jump performance. To accomplish this goal, 13 international swimmers (8 women, 5 men) were allocated to both the control (Sea Level Training, SLT) and experimental conditions (AT, 2320 m above sea level) that were separated by a one year period. All tests (15 m freestyle swimming start and loaded squat jumps with additional loads of 25%, 50%, 75%, and 100% of swimmers' body weight) were performed before and after a concurrent 3-week strength and endurance training program prescribed by the national coach...
2016: PloS One
https://www.readbyqxmd.com/read/27465634/acute-physiological-and-performance-responses-to-high-intensity-resistance-circuit-training-in-hypoxic-and-normoxic-conditions
#13
Domingo J Ramos-Campo, Jacobo A Rubio-Arias, Tomás Freitas, Arturo Camacho, José Fernando Jiménez-Diaz, Pedro E Alcaraz
The aim of this study was to analyze physical performance and physiological variables during High-Intensity Resistance Circuit Training (HRC) with the addition of two levels (moderate and high) of systemic hypoxia. Twelve resistance-trained young male subjects participated in the study. After a 6RM testing session, participants performed three randomized trials of HRC: normoxia (NORM: FiO2=0.21; ∼0 m altitude), moderate hypoxia (MH: FiO2=0.16; ∼2.100 m altitude) or high hypoxia (HH: FiO2=0.13; ∼3.800 m altitude), as controlled by a hypoxic generator...
July 19, 2016: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/27459673/four-weeks-of-classical-altitude-training-increases-resting-metabolic-rate-in-highly-trained-middle-distance-runners
#14
Amy L Woods, Avish P Sharma, Laura A Garvican-Lewis, Philo Saunders, Tony Rice, Kevin G Thompson
High altitude exposure can increase resting metabolic rate (RMR) and induce weight loss in obese populations, but there is a lack of research regarding RMR in athletes at moderate elevations common to endurance training camps. The present study aimed to determine whether four weeks of classical altitude training affects RMR in middle-distance runners. Ten highly-trained athletes were recruited for four weeks of endurance training undertaking identical programs at either 2200m in Flagstaff, Arizona (ALT, n=5) or 600m in Canberra, Australia (CON, n=5)...
August 24, 2016: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/27410774/sleep-disordered-breathing-during-live-high-train-low-in-normobaric-versus-hypobaric-hypoxia
#15
Jonas J Saugy, Laurent Schmitt, Sibylle Fallet, Raphael Faiss, Jean-Marc Vesin, Mattia Bertschi, Raphaël Heinzer, Grégoire P Millet
Saugy, Jonas J., Laurent Schmitt, Sibylle Fallet, Raphael Faiss, Jean-Marc Vesin, Mattia Bertschi, Raphaël Heinzer, and Grégoire P. Millet. Sleep disordered breathing during live high-train low in normobaric versus hypobaric hypoxia. High Alt Med Biol. 16:000-000, 2016.-The present study aimed to compare sleep disordered breathing during live high-train low (LHTL) altitude camp using normobaric hypoxia (NH) and hypobaric hypoxia (HH). Sixteen highly trained triathletes completed two 18-day LHTL camps in a crossover designed study...
July 13, 2016: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/27356568/load-management-in-elite-german-distance-runners-during-3-weeks-of-high-altitude-training
#16
Billy Sperlich, Silvia Achtzehn, Markus de Marées, Henning von Papen, Joachim Mester
There is a debate on the optimal way of monitoring training loads in elite endurance athletes especially during altitude training camps. In this case report, including nine members of the German national middle distance running team, we describe a practical approach to monitor the psychobiological stress markers during 21 days of altitude training (~2100 m above sea-level) to estimate the training load and to control muscle damage, fatigue, and/or chronic overreaching. Daily examination included: oxygen saturation of hemoglobin, resting heart rate, body mass, body and sleep perception, capillary blood concentration of creatine kinase...
June 2016: Physiological Reports
https://www.readbyqxmd.com/read/27343108/hemoglobin-mass-and-aerobic-performance-at-moderate-altitude-in-elite-athletes
#17
Jon Peter Wehrlin, Bernard Marti, Jostein Hallén
Fore more than a decade, the live high-train low (LHTL) approach, developed by Levine and Stray-Gundersen, has been widely used by elite endurance athletes. Originally, it was pointed out, that by living at moderate altitude, athletes should benefit from an increased red cell volume (RCV) and hemoglobin mass (Hbmass), while the training at low altitudes should prevent the disadvantage of reduced training intensity at moderate altitude. VO2max is reduced linearly by about 6-8 % per 1000 m increasing altitude in elite athletes from sea level to 3000 m, with corresponding higher relative training intensities for the same absolute work load...
2016: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/27337430/the-reliability-of-a-pre-loaded-treadmill-time-trial-in-moderate-normobaric-hypoxia
#18
O Shannon, M Barlow, L Duckworth, D R Woods, T Barker, A Grindrod, A Griffiths, J P O'Hara
The purpose of this study was to assess the reliability of a pre-loaded 1 500-m treadmill time trial, conducted in moderate normobaric hypoxia. 8 trained runners/triathletes (24±3 years, 73.2±8.1 kg, 182.5±6.5 cm, altitude specific V˙O2max: 52.9±5.5 ml·kg(-1)·min(-1)) completed 3 trials (the first as a familiarisation), involving 2, 15-min running bouts at 45% and 65% V˙O2max, respectively, and a 1 500-m time trial in moderate normobaric hypoxia equivalent to a simulated altitude of 2 500 m (FiO2~15%)...
September 2016: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/27322318/dietary-recommendations-for-cyclists-during-altitude-training
#19
REVIEW
Małgorzata Michalczyk, Miłosz Czuba, Grzegorz Zydek, Adam Zając, Józef Langfort
The concept of altitude or hypoxic training is a common practice in cycling. However, several strategies for training regimens have been proposed, like "live high, train high" (LH-TH), "live high, train low" (LH-TL) or "intermittent hypoxic training" (IHT). Each of them combines the effect of acclimatization and different training protocols that require specific nutrition. An appropriate nutrition strategy and adequate hydration can help athletes achieve their fitness and performance goals in this unfriendly environment...
2016: Nutrients
https://www.readbyqxmd.com/read/27274679/effect-of-wearing-the-elevation-training-mask-on-aerobic-capacity-lung-function-and-hematological-variables
#20
John P Porcari, Lauren Probst, Karlei Forrester, Scott Doberstein, Carl Foster, Maria L Cress, Katharina Schmidt
Altitude training and respiratory muscle training (RMT) have been reported to improve performance in elite and well-trained athletes. Several devices (altitude and RMT) have been developed to help athletes gain the competitive edge. The Elevation Training Mask 2.0 (ETM) purportedly simulates altitude training and has been suggested to increase aerobic capacity (VO2max), endurance performance, and lung function. Twenty-four moderately trained subjects completed 6 weeks of high-intensity cycle ergometer training...
June 2016: Journal of Sports Science & Medicine
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