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https://www.readbyqxmd.com/read/28522767/individual-hemoglobin-mass-response-to-normobaric-and-hypobaric-live-high-train-low-a-one-year-crossover-study
#1
Anna Hauser, Severin Troesch, Jonas J Saugy, Laurent Schmitt, Roberto Cejuela-Anta, Raphael Faiss, Thomas Steiner, Neil Robinson, Grégoire P Millet, Jon Peter Wehrlin
PURPOSE: To compare individual hemoglobin mass (Hbmass) changes following a live high-train low (LHTL) altitude training camp under either normobaric hypoxia (NH) or hypobaric hypoxia (HH) conditions in endurance athletes. METHODS: In a crossover design with a one-year washout, 15 male triathletes randomly performed two 18-d LHTL training camps in either HH or NH. All athletes slept at 2250 m and trained at altitudes < 1200 m. Hbmass was measured in duplicate with the optimized carbon monoxide rebreathing method before (pre-) and immediately after (post-) each 18 d training camp...
May 18, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28479953/effects-of-simulated-altitude-on-maximal-oxygen-uptake-and-inspiratory-fitness
#2
Nicole C Biggs, Benjamin S England, Nicole J Turcotte, Melissa R Cook, Alyne L Williams
Aerobic exercise at altitude has shown an increase in maximal oxygen uptake. Similar effects have been replicated by way of simulated altitude training, which have influenced various advances in the field of exercise science. Elevation Training Masks© (ETM) claim to stimulate cardiorespiratory fitness improvements similar to training at altitude, however, there is little research to support this claim. The purpose of this study was to research the effect that a hypoxia-inducing mask would have on cardiorespiratory fitness and pulmonary function through the use of a high intensity interval training (HIIT) running program...
2017: International Journal of Exercise Science
https://www.readbyqxmd.com/read/28474702/-hemoglobin-changes-hb-in-miners-exposed-to-high-altitude-and-associated-factors
#3
Christian R Mejia, Dante M Quiñones-Laveriano, Raúl Gomero, Luis Pérez-Pérez
AIM: To determine the variation of hemoglobin (Hb) in two groups of miners working at different altitudes. METHODOLOGY: A longitudinal study conducted in a private company. Hb was obtained from entrance exams and annual checks of workers at two locations: at sea level and at Peruvian highlands (4,100 m), taken by trained staff and equipment calibrated to environmental conditions. We analyzed variations in the course of the years with the PA-GEE statistical test; p values were obtained...
March 2017: Gaceta Médica de México
https://www.readbyqxmd.com/read/28453305/a-clinician-guide-to-altitude-training-for-optimal-endurance-exercise-performance-at-sea-level
#4
Keren Constantini, Daniel P Wilhite, Robert F Chapman
Constantini, Keren, Daniel P. Wilhite, and Robert F. Chapman. A clinician guide to altitude training for optimal endurance exercise performance at sea level. High Alt Med Biol 00:000-000, 2017.-For well over 50 years, endurance athletes have been utilizing altitude training in an effort to enhance performance in sea level competition. This brief review will offer the clinician a series of evidence-based best-practice guidelines on prealtitude and altitude training considerations, which can ultimately maximize performance improvement outcomes...
April 28, 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/28451905/effects-of-altitude-hypoxia-on-single-and-multiple-sprint-performance-a-comprehensive-review
#5
REVIEW
Olivier Girard, Franck Brocherie, Grégoire P Millet
Many sport competitions, typically involving the completion of single- (e.g. track-and-field or track cycling events) and multiple-sprint exercises (e.g. team and racquet sports, cycling races), are staged at terrestrial altitudes ranging from 1000 to 2500 m. Our aim was to comprehensively review the current knowledge on the responses to either acute or chronic altitude exposure relevant to single and multiple sprints. Performance of a single sprint is generally not negatively affected by acute exposure to simulated altitude (i...
April 27, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28444615/polygenic-study-of-endurance-associated-genetic-markers-ace-i-d-actn3-arg-r-577ter-x-ckmm-a-g-ncoi-and-enos-glu-g-298asp-t-in-male-gorkha-soldiers
#6
Seema Malhotra, Kiran Preet, Arvind Tomar, Shweta Rawat, Sayar Singh, Inderjeet Singh, L Robert Varte, Tirthankar Chatterjee, M S Pal, Soma Sarkar
BACKGROUND: Gorkhas, a sub-mountainous population of the Himalayan region, are known for strength and bravery. In the present study when "Gorkha" is used without brackets, we are mentioning Gorkhas of Tibeto-Burman origin. Physical capability, strength and endurance are important components of fitness associated with genetic traits. The aim of this study was to examine the endurance potential of male Gorkha soldiers, based on endurance-related genetic markers ACE I/D, ACTN3 Arg (R)577Ter(X), CKMM A/G NcoI and eNOS Glu(G)298Asp(T)...
December 2017: Sports Medicine—Open
https://www.readbyqxmd.com/read/28389828/cross-adaptation-heat-and-cold-adaptation-to-improve-physiological-and-cellular-responses-to-hypoxia
#7
REVIEW
Oliver R Gibson, Lee Taylor, Peter W Watt, Neil S Maxwell
To prepare for extremes of heat, cold or low partial pressures of oxygen (O2), humans can undertake a period of acclimation or acclimatization to induce environment-specific adaptations, e.g. heat acclimation (HA), cold acclimation (CA), or altitude training. While these strategies are effective, they are not always feasible due to logistical impracticalities. Cross-adaptation is a term used to describe the phenomenon whereby alternative environmental interventions, e.g. HA or CA, may be a beneficial alternative to altitude interventions, providing physiological stress and inducing adaptations observable at altitude...
April 7, 2017: Sports Medicine
https://www.readbyqxmd.com/read/28386237/prediction-of-critical-power-and-w-in-hypoxia-application-to-work-balance-modelling
#8
Nathan E Townsend, David S Nichols, Philip F Skiba, Sebastien Racinais, Julien D Périard
Purpose: Develop a prediction equation for critical power (CP) and work above CP (W') in hypoxia for use in the work-balance ([Formula: see text]) model. Methods: Nine trained male cyclists completed cycling time trials (TT; 12, 7, and 3 min) to determine CP and W' at five altitudes (250, 1,250, 2,250, 3,250, and 4,250 m). Least squares regression was used to predict CP and W' at altitude. A high-intensity intermittent test (HIIT) was performed at 250 and 2,250 m. Actual and predicted CP and W' were used to compute W' during HIIT using differential ([Formula: see text]) and integral ([Formula: see text]) forms of the [Formula: see text] model...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28332025/endurance-aerobic-high-intensity-and-repeated-sprint-cycling-performance-is-unaffected-by-normobaric-live-high-train-low-a-double-blind-placebo-controlled-cross-over-study
#9
Jacob Bejder, Andreas Breenfeldt Andersen, Rie Buchardt, Tanja Hultengren Larsson, Niels Vidiendal Olsen, Nikolai Baastrup Nordsborg
The aim was to investigate whether 6 weeks of normobaric "Live High-Train Low" (LHTL) using altitude tents affect highly trained athletes incremental peak power, 26-km time-trial cycling performance, 3-min all-out performance, and 30-s repeated sprint ability. In a double-blinded, placebo-controlled cross-over design, seven highly trained triathletes were exposed to 6 weeks of normobaric hypoxia (LHTL) and normoxia (placebo) for 8 h/day. LHTL exposure consisted of 2 weeks at 2500 m, 2 weeks at 3000 m, and 2 weeks at 3500 m...
May 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28291666/risk-and-protective-factors-for-sudden-cardiac-death-during-leisure-activities-in-the-mountains-an-update
#10
REVIEW
Martin Burtscher
INTRODUCTION: Annually, more than 100 million tourists with widely varying health and fitness status are attracted by the mountainous areas around the world. Whereas mountaineering activities may contribute to the well established beneficial effects of regular exercise, for certain individuals these activities are also associated with a relatively high risk of death. METHODS: This manuscript presents an updated overview of risk and protective factors for sudden cardiac death during leisure activities in the mountains...
February 28, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27932989/hypoxic-living-and-exercise-training-alter-adipose-tissue-leptin-leptin-receptor-in-rats
#11
Yingli Lu, Lianshi Feng, Minhao Xie, Li Zhang, Jianfang Xu, Zihong He, Tongjian You
Background: Hypobaric hypoxia results in weight loss in obese individuals, and exercise training is advocated for the treatment of obesity and its related metabolic dysfunctions. The purpose of this study was to investigate the effects of hypoxic living and exercise training on obesity and adipose tissue leptin/leptin receptor in dietary-induced obese rats. Methods: One hundred and thirty high-fat diet fed Sprague-Dawley rats were assigned into one of the following groups (n = 10 each): control, sedentary hypoxic living for 1-4 weeks (SH1, SH2, SH3, and SH4), living, and exercise training in normoxic conditions for 1-4 weeks (TN1, TN2, TN3, and TN4), and living and exercise training in hypoxic conditions for 1-4 weeks (TN1, TN2, TN3, and TN4)...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27923417/mechanisms-of-memory-dysfunction-during-high-altitude-hypoxia-training-in-military-aircrew
#12
Daniel A Nation, Mark W Bondi, Ellis Gayles, Dean C Delis
OBJECTIVES: Cognitive dysfunction from high altitude exposure is a major cause of civilian and military air disasters. Pilot training improves recognition of the early symptoms of altitude exposure so that countermeasures may be taken before loss of consciousness. Little is known regarding the nature of cognitive impairments manifesting within this critical window when life-saving measures may still be taken. Prior studies evaluating cognition during high altitude simulation have predominantly focused on measures of reaction time and other basic attention or motor processes...
January 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/27906593/does-swimming-at-a-moderate-altitude-favor-a-lower-oxidative-stress-in-an-intensity-dependent-manner-role-of-nonenzymatic-antioxidants
#13
Rafael A Casuso, Jerónimo Aragón-Vela, Gracia López-Contreras, Silvana N Gomes, Cristina Casals, Yaira Barranco-Ruiz, Jordi J Mercadé, Jesus R Huertas
Casuso, Rafael A., Jerónimo Aragón-Vela, Gracia López-Contreras, Silvana N. Gomes, Cristina Casals, Yaira Barranco-Ruiz, Jordi J. Mercadé, and Jesus R. Huertas. Does swimming at a moderate altitude favor a lower oxidative stress in an intensity-dependent manner? Role of nonenzymatic antioxidants. High-Alt Med Biol. 18:46-55, 2017.-we aimed to describe oxidative damage and enzymatic and nonenzymatic antioxidant responses to swimming at different intensities in hypoxia. We recruited 12 highly experienced swimmers who have been involved in competitive swimming for at least 9 years...
March 2017: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/27820657/prevalence-of-and-risk-factors-for-trachoma-in-oromia-regional-state-of-ethiopia-results-of-79-population-based-prevalence-surveys-conducted-with-the-global-trachoma-mapping-project
#14
Berhanu Bero, Colin Macleod, Wondu Alemayehu, Solomon Gadisa, Ahmed Abajobir, Yilikal Adamu, Menbere Alemu, Liknaw Adamu, Michael Dejene, Addis Mekasha, Zelalem Habtamu Jemal, Damtew Yadeta, Oumer Shafi, Genet Kiflu, Rebecca Willis, Rebecca M Flueckiger, Brian K Chu, Alexandre L Pavluck, Anthony W Solomon
PURPOSE: To complete the baseline trachoma map in Oromia, Ethiopia, by determining prevalences of trichiasis and trachomatous inflammation - follicular (TF) at evaluation unit (EU) level, covering all districts (woredas) without current prevalence data or active control programs, and to identify factors associated with disease. METHODS: Using standardized methodologies and training developed for the Global Trachoma Mapping Project, we conducted cross-sectional community-based surveys from December 2012 to July 2014...
November 7, 2016: Ophthalmic Epidemiology
https://www.readbyqxmd.com/read/27779956/emergency-medical-considerations-in-a-space-suited-patient
#15
Alejandro Garbino, Derek M Nusbaum, Daniel M Buckland, Anil S Menon, Jonathan B Clark, Erik L Antonsen
The Stratex Project is a high altitude balloon flight that culminated in a freefall from 41,422 m (135,890 ft), breaking the record for the highest freefall to date. Crew recovery operations required an innovative approach due to the unique nature of the event as well as the equipment involved. The parachutist donned a custom space suit similar to a NASA Extravehicular Mobility Unit (EMU), with life support system mounted to the front and a parachute on the back. This space suit had a metal structure around the torso, which, in conjunction with the parachute and life support assembly, created a significant barrier to extraction from the suit in the event of a medical emergency...
2016: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/27766103/development-of-prediction-model-and-experimental-validation-in-predicting-the-curcumin-content-of-turmeric-curcuma-longa-l
#16
Abdul Akbar, Ananya Kuanar, Raj K Joshi, I S Sandeep, Sujata Mohanty, Pradeep K Naik, Antaryami Mishra, Sanghamitra Nayak
The drug yielding potential of turmeric (Curcuma longa L.) is largely due to the presence of phyto-constituent 'curcumin.' Curcumin has been found to possess a myriad of therapeutic activities ranging from anti-inflammatory to neuroprotective. Lack of requisite high curcumin containing genotypes and variation in the curcumin content of turmeric at different agro climatic regions are the major stumbling blocks in commercial production of turmeric. Curcumin content of turmeric is greatly influenced by environmental factors...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27750391/clarification-on-altitude-training
#17
LETTER
Grégoire P Millet, Franck Brocherie, Raphael Faiss, Olivier Girard
No abstract text is available yet for this article.
January 1, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/27667380/cardiovascular-effects-of-altitude-on-performance-athletes
#18
Ankit B Shah, Neil Coplan
Altitude plays an important role in cardiovascular performance and training for athletes. Whether it is mountaineers, skiers, or sea-level athletes trying to gain an edge by training or living at increased altitude, there are many potential benefits and harms of such endeavors. Echocardiographic studies done on athletes at increased altitude have shown evidence for right ventricular dysfunction and pulmonary hypertension, but no change in left ventricular ejection fraction. In addition, 10% of athletes are susceptible to pulmonary hypertension and high-altitude pulmonary edema...
2016: Reviews in Cardiovascular Medicine
https://www.readbyqxmd.com/read/27622961/yoga-practice-improves-physiological-and-biochemical-status-at-high-altitudes-a-prospective-case-control-study
#19
RANDOMIZED CONTROLLED TRIAL
Gidugu Himashree, Latika Mohan, Yogesh Singh
UNLABELLED: Context • High altitude (HA) is a psychophysiological stressor for natives of lower altitudes. Reducing the morbidity and optimizing the performance of individuals deployed in an HA region has been attempted and reported with varied results. Objective • The present study intended to explore the effects of comprehensive yogic practices on the health and performance of Indian soldiers deployed at HAs. Design • The research team designed a prospective, randomized, case-control study...
September 2016: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/27583364/exercise-induced-hypoxaemia-developed-at-sea-level-influences-responses-to-exercise-at-moderate-altitude
#20
Anne-Fleur Gaston, Fabienne Durand, Emma Roca, Grégory Doucende, Ilona Hapkova, Enric Subirats
PURPOSE: The aim of this study was to investigate the impact of exercise-induced hypoxaemia (EIH) developed at sea-level on exercise responses at moderate acute altitude. METHODS: Twenty three subjects divided in three groups of individuals: highly trained with EIH (n = 7); highly trained without EIH (n = 8) and untrained participants (n = 8) performed two maximal incremental tests at sea-level and at 2,150 m. Haemoglobin O2 saturation (SpO2), heart rate, oxygen uptake (VO2) and several ventilatory parameters were measured continuously during the tests...
2016: PloS One
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