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https://www.readbyqxmd.com/read/28333820/committee-opinion-no-692-emergent-therapy-for-acute-onset-severe-hypertension-during-pregnancy-and-the-postpartum-period
#1
(no author information available yet)
Acute-onset, severe systolic hypertension; severe diastolic hypertension; or both can occur during the prenatal, intrapartum, or postpartum periods. Pregnant women or women in the postpartum period with acute-onset, severe systolic hypertension; severe diastolic hypertension; or both require urgent antihypertensive therapy. Introducing standardized, evidence-based clinical guidelines for the management of patients with preeclampsia and eclampsia has been demonstrated to reduce the incidence of adverse maternal outcomes...
April 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28333812/committee-opinion-no-692-summary-emergent-therapy-for-acute-onset-severe-hypertension-during-pregnancy-and-the-postpartum-period
#2
(no author information available yet)
Acute-onset, severe systolic hypertension; severe diastolic hypertension; or both can occur during the prenatal, intrapartum, or postpartum periods. Pregnant women or women in the postpartum period with acute-onset, severe systolic hypertension; severe diastolic hypertension; or both require urgent antihypertensive therapy. Introducing standardized, evidence-based clinical guidelines for the management of patients with preeclampsia and eclampsia has been demonstrated to reduce the incidence of adverse maternal outcomes...
April 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28333180/influence-of-the-disease-label-polycystic-ovary-syndrome-on-intention-to-have-an-ultrasound-and-psychosocial-outcomes-a-randomised-online-study-in-young-women
#3
Tessa Copp, Kirsten McCaffery, Lamiae Azizi, Jenny Doust, Ben W J Mol, Jesse Jansen
STUDY QUESTION: Does the disease label 'polycystic ovary syndrome' (PCOS) have an impact on desire for medical testing and psychosocial outcomes? SUMMARY ANSWER: When given the disease label PCOS in a hypothetical scenario, participants had higher intention to have an ultrasound, perceived the condition to be more severe and had lower self-esteem than those not given the disease label. WHAT IS KNOWN ALREADY: Widening diagnostic criteria and improved imaging sensitivity have increased the number of reproductive-aged women diagnosed with PCOS from 4% to 8% to up to 21%...
February 18, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28333123/objective-video-quality-assessment-based-on-machine-learning-for-underwater-scientific-applications
#4
José-Miguel Moreno-Roldán, Miguel-Ángel Luque-Nieto, Javier Poncela, Pablo Otero
Video services are meant to be a fundamental tool in the development of oceanic research. The current technology for underwater networks (UWNs) imposes strong constraints in the transmission capacity since only a severely limited bitrate is available. However, previous studies have shown that the quality of experience (QoE) is enough for ocean scientists to consider the service useful, although the perceived quality can change significantly for small ranges of variation of video parameters. In this context, objective video quality assessment (VQA) methods become essential in network planning and real time quality adaptation fields...
March 23, 2017: Sensors
https://www.readbyqxmd.com/read/28331764/how-many-of-the-biopsy-decisions-taken-at-inexperienced-breast-radiology-units-were-correct
#5
Özlem Demircioğlu, Meral Uluer, Erkin Arıbal
OBJECTIVE: In this study, we aimed to determine the need for biopsy in patients referred from other clinics for the performance of biopsy with the suspicion of breast cancer. MATERIALS AND METHODS: 112 patients were included in the study. It was decided that their biopsies be performed following examinations in other clinics and they presented to the breast radiology unit of our hospital for a second opinion. The demographic characteristics, diagnostic studies completed in the other centers, properties of lesions, decision made as a result of examinations and BI-RADS (Breast Imaging Reporting and Data Systems) categorizations were recorded on the registration forms of the study patients...
January 2017: J Breast Health (2013)
https://www.readbyqxmd.com/read/28328691/factors-associated-with-discharge-home-after-transfer-to-a-pediatric-emergency-department
#6
Erin R Peebles, Michael R Miller, Tim P Lynch, Janice A Tijssen
OBJECTIVES: The transfer of children from community emergency departments (EDs) to tertiary care pediatric EDs for investigations, interventions, or a second opinion is common. In order to improve health care system efficiency, we must have a better understanding of this population and identify areas for education and capacity building. METHODS: We conducted a retrospective chart review of all patients (aged 0-17 years) who were transferred from community ED to a pediatric ED from November 2013 to November 2014...
March 21, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/28301207/second-opinion-review-of-breast-imaging-at-a-cancer-center-is-it-worthwhile
#7
Kristen Coffey, Donna D'Alessio, Delia M Keating, Elizabeth A Morris
OBJECTIVE: Second-opinion review of breast imaging studies can be a time-consuming and labor-intensive process. The purpose of this investigation was to determine whether reinterpretation of studies obtained at institutions outside a cancer center influences clinical management, specifically by revealing additional cancer and preventing unnecessary biopsy. MATERIALS AND METHODS: A review was conducted of breast imaging studies of 200 patients who underwent ultrasound and MRI at community facilities and had the images submitted for second opinions at a cancer center between January and April 2014...
March 16, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28295494/seeds-in-the-appendix-a-fruitful-exploration
#8
Michela Campora, Chiara Trambaiolo Antonelli, Federica Grillo, Alberto Bragoni, Laura Cornara, Paola Migliora, Simona Pigozzi, Luca Mastracci
Our contribution aims at clarifying and underlining a possible finding which can pose an interesting twist in routine appendix diagnostics: seeds in the appendiceal lumen, their histological aspects and their differential diagnosis with parasites. We work in a training centre with a large referral practice for gastrointestinal pathology and often the most banal cases are those which pose problems to junior or non-expert pathologists. This short study aims at providing simple iconographic tables, which are not at the moment available either in publications or on the web, with the most frequent seeds encountered in our routine practice or sent for second opinion...
March 10, 2017: Histopathology
https://www.readbyqxmd.com/read/28294105/breath-acetone-as-a-potential-marker-in-clinical-practice
#9
Vera Ruzsanyi, Miklós Kalapos
In recent decades, two facts have changed the opinion of researchers about the function of acetone in humans. Firstly, it has turned out that acetone cannot be regarded as simply a waste product of metabolism, because there are several pathways in which acetone is produced or broken down. Secondly, methods have emerged making possible its detection in exhaled breath, thereby offering an attractive alternative to investigation of blood and urine samples. From a clinical point of view the measurement of breath acetone levels are important, but there are limitations to its wide application...
March 15, 2017: Journal of Breath Research
https://www.readbyqxmd.com/read/28292000/-the-new-second-opinion-procedure
#10
A Wienke
No abstract text is available yet for this article.
February 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28291158/value-of-second-opinion-review-of-outside-institution-pet-ct-examinations
#11
Gary A Ulaner, Lorenzo Mannelli, Mark Dunphy
OBJECTIVE: This study aimed to determine whether second-opinion reviews of PET/CT examinations by subspecialists alter reporting of malignant findings. MATERIALS AND METHODS: This IRB-approved study compared 240 fluorine-18 fluorodeoxyglucose PET/CT consecutively dictated reports by two nuclear medicine subspecialists against the original outside institution reports. Subspecialist reviews documented whether malignant findings on the outside report were malignant and noted additional malignant findings not described on the outside report...
April 2017: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/28290337/perceptions-of-australian-clients-towards-male-radiographers-working-in-breast-imaging-quantitative-results-from-a-pilot-study
#12
H M Warren-Forward, B Mackie, M Alchin, T Mooney, P Fitzpatrick
AIM: Breast cancer is the second most common cause of cancer-related death in Australian women, therefore early breast cancer detection is essential. Female radiographers currently conduct breast screening in Australia; however there is a projected shortage. With many women already feeling apprehensive about attending a breast examination, possible proposals to fill this shortage must be carefully considered. Training male radiographers is one proposal however, this raises some gender concerns...
February 2017: Radiography
https://www.readbyqxmd.com/read/28286926/informal-hallway-medical-consultation-in-orthopedics-is-it-as-common-as-it-seems
#13
Leonid Kandel, Yair Barzilay, Adi Friedman, Idan Ilsar, Ori Safran, Yoav Mattan
INTRODUCTION: Informal (hallway) medical consultation is an integral part of the physician's work. As musculoskeletal complaints are very common, orthopedic surgeons stand in the frontline of this practice. Many of these consultations are poorly, if at all, documented, thus imposing a potential medical danger to the patient and a medicolegal danger to the surgeon. We conducted this first study to examine whether this practice is common among the orthopedic surgeons in university hospital...
March 12, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28286028/spindle-cell-oncocytoma-report-of-two-cases-with-massive-bleeding-and-review-of-the-literature
#14
REVIEW
Domenico Billeci, Elisabetta Marton, Enrico Giordan, Valentina Carraro, Monica Ronzon, Sabrina Rossi
Spindle cell oncocytoma (SCO) is a rare pituitary tumor, classified as a WHO grade I neoplasm. Due to its rarity, SCO is often preoperatively misdiagnosed as a pituitary macroadenoma. In the present study we report two recent cases of SCO, a 61-year-old male and a 65-year-old female presenting at Treviso General Hospital between March 2014 and April 2015. Tumor resection was achieved by endoscopic transsphenoidal approach but massive hemorrhagic events hampered surgery, endangering the patient's life in both cases...
March 9, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28277837/an-overview-of-ca-2-mobilization-assays-in-gpcr-drug-discovery
#15
Qiang Ma, Lingyan Ye, Hongxia Liu, Ying Shi, Naiming Zhou
Calcium ions (Ca(2+)) serve as a second messenger or universal signal transducer implicated in the regulation of a wide range of physiological processes. A change in the concentration of intracellular Ca(2+) is an important step in intracellular signal transduction. G protein-coupled receptors (GPCRs), the largest and most versatile group of cell surface receptors, transduce extracellular signals into intracellular responses via their coupling to heterotrimeric G proteins. Since Ca(2+) plays a crucial role in GPCR-induced signaling, measurement of intracellular Ca(2+) has attracted more and more attention in GPCR-targeted drug discovery...
March 4, 2017: Expert Opinion on Drug Discovery
https://www.readbyqxmd.com/read/28276967/near-infrared-biophotonics-based-nanodrug-release-systems-and-their-potential-application-for-neuro-disorders
#16
Vidya Sagar, Madhavan Nair
Near-infrared ray (NIR)-responsive 'smart' nanoagents allow spatial and temporal control over the drug delivery process, noninvasively, without affecting healthy tissues and therefore they possess high potential for on-demand, targeted drug/gene delivery. Various NIR-responsive drug/gene delivery techniques are under investigation for peripheral disorders (especially for cancer). Nonetheless, their potential not been extensively examined for brain biomedical application. Areas covered: This review focuses on NIR-responsive characteristics of different NIR-nanobiophotonics-based nanoagents and associated drug delivery strategies...
February 28, 2017: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/28276858/the-safety-of-second-line-treatment-options-for-non-small-cell-lung-cancer
#17
Antonio Rossi, Paolo Maione, Giuseppe Santabarbara, Paola Claudia Sacco, Francesca Casaluce, Assunta Sgambato, Maria Luisa Barzelloni, Giovanni Palazzolo, Cesare Gridelli
Non-small-cell lung cancer (NSCLC) patients after first-line therapy ultimately suffer progression. At this time, many patients still have a good performance status and can be considered for further active treatment. Two chemotherapeutic agents, docetaxel and pemetrexed (only in non-squamous histology), and the biological drug anti-epidermal growth factor receptor (EGFR) erlotinib, were approved for clinical use in the second-line treatment of NSCLC patients. In the last few years further new second-line therapies have become available in the clinical practice...
March 1, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28276856/safety-of-alectinib-for-the-treatment-of-metastatic-alk-rearranged-non-small-cell-lung-cancer
#18
Viola Zhu, S H Ou
Patients with anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) may derive significant clinical benefit from targeted therapies against this driver mutation, but progression is virtually inevitable. Alectinib is a next-generation ALK inhibitor that provides a novel treatment option for this group of patients. Areas covered: In this review, we summarize the overall safety and tolerability of alectinib. Specifically, we cover cardiovascular, gastrointestinal, hepatic, musculoskeletal, and respiratory adverse events...
March 3, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28274852/curcumin-as-a-potential-protective-compound-against-cardiac-diseases
#19
REVIEW
Shuai Jiang, Jing Han, Tian Li, Zhenlong Xin, Zhiqiang Ma, Wencheng Di, Wei Hu, Bing Gong, Shouyin Di, Dongjin Wang, Yang Yang
Curcumin, which was first used 3000 years ago as an anti-inflammatory agent, is a well-known bioactive compound derived from the active ingredient of turmeric (Curcuma longa). Previous research has demonstrated that curcumin has immense therapeutic potential in a variety of diseases via anti-oxidative, anti-apoptotic, and anti-inflammatory pathways. Cardiac diseases are the leading cause of mortality worldwide and cause considerable harm to human beings. Numerous studies have suggested that curcumin exerts a protective role in the human body whereas its actions in cardiac diseases remain elusive and poorly understood...
March 6, 2017: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/28274671/second-opinion-oral-pathology-referrals-in-new-zealand
#20
B Seo, H M Hussaini, A M Rich
Referral for a second opinion is an important aspect of pathology practice, which reduces the rate of diagnostic error and ensures consistency with diagnoses. The Oral Pathology Centre (OPC) is the only specialist oral diagnostic centre in New Zealand. OPC provides diagnostic services to dentists and dental specialists throughout New Zealand and acts as a referral centre for second opinions for oral pathology specimens that have been sent to anatomical pathologists. The aim of this study was to review second opinion referral cases sent to the OPC over a 15-year period and to assess the levels of concordance between the original and final diagnoses...
March 5, 2017: Pathology
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