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https://www.readbyqxmd.com/read/28631181/glaucoma-awareness-amongst-glaucoma-patients-seeking-a-second-opinion
#1
Devindra Sood, Shivam Sood, Ishaana Sood, Dinesh Kumar, Rajeev Sood, Narender Nath Sood
PURPOSE: The aim of the study was to assess level of glaucoma awareness amongst glaucoma patients by studying characteristics amongst urban and rural glaucoma populations in North India. METHODS: A questionnaire was designed and administered after appropriate validation amongst patients to identify determinants of glaucoma awareness. Trained personnel delivered the 11 questions to 1506 patients, aged 18 and above through random sampling. The questionnaire evaluated source of awareness, education, gender, location and age on the level of awareness of glaucoma...
June 19, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28629443/parents-and-guardians-perceptions-on-availability-and-pricing-of-medicines-and-healthcare-for-children-in-ethekwini-south-africa-a-qualitative-study
#2
Velisha Ann Perumal-Pillay, Fatima Suleman
BACKGROUND: Inadequate access to affordable essential medicines poses a challenge to achieving Universal Health Coverage. Access to essential medicines for children has been in the spotlight in recent research. However, information from the end users of medicines, i.e. patients is scarce. Obtaining information at a household level is integral to understanding how people access, obtain and use medicines. This study aimed to gather opinions and perceptions from parents/guardians on availability, affordability and quality of medicines and healthcare for children in SA...
June 19, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28626824/atypical-chronic-central-serous-chorioretinopathy-with-cystoid-macular-edema-therapeutic-response-to-medical-and-laser-therapy
#3
Jiun L Do, Lisa C Olmos de Koo, Hossein Ameri
PURPOSE: To describe an atypical case of chronic central serous chorioretinopathy (CSCR). METHODS: A 58-year-old man with longstanding, bilateral visual impairment was self-referred for a second opinion. RESULTS: Findings by direct ophthalmoscopy, optical coherence tomography, fluorescein angiography, and fundus autofluorescence (FAF) were suggestive of atypical, chronic CSCR. Treatment with oral anti-mineralocorticoids resulted in moderate improvement, and photodynamic therapy (PDT) had minimal effect...
June 2017: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/28621963/-taking-altruistic-surrogacy-seriously
#4
Vicente Bellver Capella
Since two years ago Spanish public opinion is living an intense debate on the ethical and legal aspects about surrogacy. There is a shared concern about the risks of exploitation for women related to commercial surrogacy. To get rid of them, and make possible at the same time that people who is not able to gestate could become father/mother, it has been proposed to regulate altruistic surrogacy. In order to defend this proposal it is said that there is an analogy between altruistic organ donation and altruistic surrogacy: you can help a person in need giving an organ or your ability to gestate...
May 2017: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
https://www.readbyqxmd.com/read/28619867/journalism-ethics-and-the-goldwater-rule-in-a-post-truth-media-world
#5
Meredith A Levine
This article strongly supports the Goldwater Rule, a position arrived at through an exploration of journalism ethics and practice norms for reporting on public figures, and justified by three claims. First, there is a seldom-acknowledged contradiction in ethics when it comes to journalistic reporting on public figures, one that is increasingly difficult to navigate in the current media climate. Second, the goal of informing and educating the public through offering a professional opinion about the mental health of public figures is often misaligned with the realities of journalistic storytelling...
June 2017: Journal of the American Academy of Psychiatry and the Law
https://www.readbyqxmd.com/read/28616377/blue-after-splenectomy
#6
Taaran Cariappa Ballachanda Subbaiah, Jeremy P Feldman
INTRODUCTION: We present a 51 year old, African American, female who presented with persistent hypoxemia. She had been taking dapsone for many years for prophylaxis against Pneumocystic Jiroveci with no symptoms but eventually developed methemoglobinemia only after a splenectomy. From our literature review there are no documented cases that have demonstrated this relationship between dapsone, splenic function and methemoglobin and we hope to share our perplexing case and shed light on the interaction...
2017: Respiratory Medicine Case Reports
https://www.readbyqxmd.com/read/28612633/granisetron-in-the-treatment-of-chemotherapy-induced-nausea-and-vomiting-cinv-is-there-still-a-role-after-comparison-with-palonosetron
#7
Sheila A Doggrell
Chemotherapy-induced nausea and vomiting (CINV) has a negative impact on the lives of subjects receiving chemotherapy. In 2009, the second generation 5-HT3-receptor antagonist, palonosetron, which is longer-acting than granisetron, was shown, as part of dual therapy with dexamethasone, to be superior to intravenous granisetron in the delayed phase of CINV. Area covered: In an attempt to maintain plasma levels of granisetron during the delayed phase of CINV, longer-acting preparations of granisetron have been manufactured...
June 19, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28608992/student-and-recent-graduate-perspectives-on-radiological-imaging-instruction-during-basic-anatomy-courses
#8
Andrew W Phillips, Hunter Eason, Christopher M Straus
Recently, faculty at Pritzker School of Medicine, The University of Chicago, have made efforts to improve the depth of radiological anatomy knowledge that students have, but no insights exist as to student and resident opinions of how clinically helpful deep anatomical understanding is. A single-institution survey of second- and fourth-year medical students and postgraduate year 1-4 residents from 11 specialties, composed of five-point Likert questions, sample examination questions, and narrative response questions, was distributed in 2015...
June 13, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28608761/biomedical-applications-of-yeast-a-patent-view-part-one-yeasts-as-workhorses-for-the-production-of-therapeutics-and-vaccines
#9
Farzin Roohvand, Mehdi Shokri, Meghdad Abdollahpour-Alitappeh, Parastoo Ehsani
Yeasts, as Eukaryotes, offer unique features for ease of growth and genetic manipulation possibilities, making it an exceptional microbial host. Areas covered: This review provides general and patent-oriented insights into production of biopharmaceuticals by yeasts. Patents, wherever possible, were correlated to the original or review articles. The review describes applications of major GRAS (generally regarded as safe) yeasts for the production of therapeutic proteins and subunit vaccines; additionally, immunomodulatory properties of yeast cell wall components were reviewed for use of whole yeast cells as a new vaccine platform...
June 13, 2017: Expert Opinion on Therapeutic Patents
https://www.readbyqxmd.com/read/28608730/novel-therapy-for-childhood-acute-lymphoblastic-leukemia
#10
Raoul Santiago, Stéphanie Vairy, Daniel Sinnett, Maja Krajinovic, Henrique Bittencourt
During recent decades, the prognosis of childhood acute lymphoblastic leukemia (ALL) has improved dramatically, nowadays, reaching a cure rate of almost 90%. These results are due to a better management and combination of old therapies, refined risk-group stratification and emergence of minimal residual disease (MRD) combined with treatment's intensification for high-risk subgroups. However, the subgroup of patients with refractory/relapsed ALL still presents a dismal prognosis indicating necessity for innovative therapeutic approaches...
June 13, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28607337/safety-aspects-of-desflurane-anesthesia-and-laryngeal-mask-airway
#11
Marco Rossi, Antonio Corcione, Clelia Esposito, Massimo Micaglio, Roberta Monzani, Carlo Ori
Laryngeal mask (LM) and inhaled anesthesia combination is often deemed unsuitable. Actually the evolution of surgical procedures towards minimal invasiveness, the search of improved productivity, and the contemporary need for patient safety and faster recovery, push the anesthetists to get interested in their use in the daily practice. An Expert Panel composed by anesthetists coming from university and tertiary hospitals undertook to write an Expert Opinion on the correct management of LM and desflurane in adult patients, with a view to issuing a simple operative protocol for their combined intraoperative usage...
June 12, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28606972/patient-driven-second-opinions-in-oncology-a-systematic-review
#12
Marij A Hillen, Niki M Medendorp, Joost G Daams, Ellen M A Smets
BACKGROUND: Although patient-driven second opinions are increasingly sought in oncology, the desirability of this trend remains unknown. Therefore, this systematic review assesses evidence on the motivation for and frequency of requests for second opinions and examines how they evolve and their consequences for oncological practice. MATERIALS AND METHODS: Relevant databases were sought using the terms "cancer," "second opinion," and "self-initiated." Included were peer-reviewed articles that reported on patient-initiated second opinions within oncology...
June 12, 2017: Oncologist
https://www.readbyqxmd.com/read/28606480/sphingosine-kinase-2-in-autoimmune-inflammatory-disease-and-the-development-of-sphingosine-kinase-2-inhibitors
#13
REVIEW
Nigel J Pyne, David R Adams, Susan Pyne
The purpose of this Opinion is to present a case for targeting sphingosine kinase 2 (SK2) in autoimmune/inflammatory disease. Data obtained using Sphk2(-/-) mice suggest that SK2 is an anti-inflammatory enzyme, although this might be misleading because of a compensatory increase in the expression of a second isoform, sphingosine kinase 1 (SK1), which functions as a proinflammatory enzyme. SK2 is involved in regulating interleukin (IL)-12/interferon gamma (IFN-γ) and histone deacetylase-1/2 (HDAC-1/2) signalling and, potentially, retinoid-related orphan receptor gamma t (ROR-γt) stability linked with T helper (Th) 17 cell polarisation...
June 9, 2017: Trends in Pharmacological Sciences
https://www.readbyqxmd.com/read/28603612/exposure-to-the-drug-company-marketing-in-greece-interactions-and-attitudes-in-a-non-regulated-environment-for-medical-students
#14
Magdalini Filippiadou, Dimitrios Kouvelas, Georgios Garyfallos, Ioannis Tsakiridis, Dimitrios Tzachanis, Dimitrios Spachos, Georgios Papazisis
BACKGROUND: Medical students are targeted by the pharmaceutical industry and are exposed to their marketing strategies even in the preclinical years of study. The marketing strategies used by pharmaceutical companies with physicians are also applied to students, affecting their future prescribing behaviour, and include low-cost non-educational gifts, travel expenses and conferences registration fees. In Greece, there are no national or institutional regulations and guidelines concerning drug company-medical student interactions...
July 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28602101/expert-panel-on-practice-patterns-in-the-management-of-cow-s-milk-protein-allergy-and-associated-economic-burden-of-disease-on-health-service-in-turkey
#15
Bulent Enis Sekerel, Oznur Seyhun
AIMS: To evaluate practice patterns in the management of cow's milk protein allergy (CMPA) and associated economic burden of disease on health service in Turkey. MATERIALS AND METHODS: This study was based on experts' views on the practice patterns in management of CMPA manifesting with either proctocolitis or eczema symptoms and thereby to estimate economic burden of CMPA. Practice patterns were determined via patient flow charts developed by experts using modified Delphi method for CMPA presented with proctocolitis and eczema...
June 12, 2017: Journal of Medical Economics
https://www.readbyqxmd.com/read/28601261/second-opinion-in-medical-encounters-a-study-among-breast-cancer-patients
#16
Sophie E Groß, Marij A Hillen, Holger Pfaff, Nadine Scholten
OBJECTIVE: To examine the association between whether physicians discuss the possibility of seeking a second opinion (SO) with patients and the patients' decision to seek an SO. We also investigated the impact of seeking such an opinion on patients' trust in physicians. METHODS: Newly diagnosed breast cancer patients were surveyed postoperatively with a mail survey. A patient survey is carried out annually to evaluate the breast cancer centers in North Rhine-Westphalia, Germany...
June 3, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28599637/recruitment-of-racial-ethnic-minority-older-adults-through-community-sites-for-focus-group-discussions
#17
Mary E Northridge, Michele Shedlin, Eric W Schrimshaw, Ivette Estrada, Leydis De La Cruz, Rogelina Peralta, Stacia Birdsall, Sara S Metcalf, Bibhas Chakraborty, Carol Kunzel
BACKGROUND: Despite a body of evidence on racial/ethnic minority enrollment and retention in research, literature specifically focused on recruiting racially/ethnically diverse older adults for social science studies is limited. There is a need for more rigorous research on methodological issues and the efficacy of recruitment methods. Cultural obstacles to recruitment of racial/ethnic minority older adults include language barriers, lack of cultural sensitivity of target communities on the part of researchers, and culturally inappropriate assessment tools...
June 9, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28597467/development-of-indicators-for-evaluating-the-appropriate-use-of-triazoles-for-invasive-fungal-disease-a-delphi-panel-survey
#18
W H Dong, G Z Zhang, J X Li, Y Wang, T T Wang, Y L Dong
WHAT IS KNOWN AND OBJECTIVES: Triazoles including fluconazole, itraconazole, voriconazole and posaconazole are now widely used, whereas in some countries, they are reportedly used in inappropriate way frequently; thus, it is clearly a matter of urgency to regulate the use of triazole drugs. Several studies have made good attempts to evaluate antifungal use, but they did not cover the entire medication process. This study aimed to establish indicators for the appropriate use of triazoles for invasive fungal disease, so as to produce a reference for evaluating and standardizing the rational application of triazole antifungals...
June 8, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28594453/risk-factors-associated-with-defaulting-from-visceral-leishmaniasis-treatment-analysis-under-routine-program-conditions-in-bihar-india
#19
S Kansal, J Chakravarty, A Kumar, P Malaviya, M Boelaert, E Hasker, B Ostyn, S Sundar
OBJECTIVE: To assess the rate of default from treatment in the Visceral Leishmaniasis (VL) Elimination Program and to identify risk factors and its underlying causes. METHODS: Case control study conducted between December 2009 and June 2012 in three Primary Health Centres (PHC) of Muzaffarpur District, India. Patients who defaulted from treatment from the PHCs were considered as "cases", and those who completed their treatment as "controls". Two controls were included in the study for each case...
June 8, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28593042/challenges-facing-the-veterinary-profession-in-ireland-1-clinical-veterinary-services
#20
Manuel Magalhães-Sant'Ana, Simon J More, David B Morton, Alison J Hanlon
BACKGROUND: The provision of veterinary clinical services is known to elicit a range of challenges which require an ethical appraisal. In a recent Policy Delphi study, referrals/second opinions and 24 h emergency care were identified as matters of key concern by veterinary professionals in Ireland. In this case study (the first in a series of three resulting from a research workshop exploring challenges facing the veterinary profession in Ireland; the other two case studies investigate the on-farm use of veterinary antimicrobials and emergency/casualty slaughter certification) we aim to provide a value-based reflection on the constraints and possible opportunities for two prominent veterinary clinical services in Ireland: referrals/second opinions and 24 h emergency care...
2017: Irish Veterinary Journal
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