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https://www.readbyqxmd.com/read/27345276/-efficacy-of-lisdexamphetamine-to-improve-the-behavioural-and-cognitive-symptoms-of-attention-deficit-hyperactivity-disorder-treatment-monitored-by-means-of-the-aula-nesplora-virtual-reality-test
#1
U Diaz-Orueta, M A Fernandez-Fernandez, M D Morillo-Rojas, G Climent
INTRODUCTION: Lisdexanfetamine (LDX) is the drug for attention deficit hyperactivity disorder (ADHD) undergoing the largest research volume in the latest years. However, no studies certify its usefulness for the improvement of cognitive functioning in ADHD. AIM: To evaluate the efficacy of LDX in the behavioral and cognitive improvement of a group of patients with ADHD. Such efficacy was measured by means of the administration of AULA Nesplora virtual reality test before the prescription of pharmacological treatment and right after the treatment with LDX...
July 1, 2016: Revista de Neurologia
https://www.readbyqxmd.com/read/27258210/virtual-reality-based-attention-assessment-of-adhd-clinicavr-classroom-cpt-versus-a-traditional-continuous-performance-test
#2
Alexandra Neguț, Anda Maria Jurma, Daniel David
Virtual-reality-based assessment may be a good alternative to classical or computerized neuropsychological assessment due to increased ecological validity. ClinicaVR: Classroom-CPT (VC) is a neuropsychological test embedded in virtual reality that is designed to assess attention deficits in children with attention deficit hyperactivity disorder (ADHD) or other conditions associated with impaired attention. The present study aimed to (1) investigate the diagnostic validity of VC in comparison to a traditional continuous performance test (CPT), (2) explore the task difficulty of VC, (3) address the effect of distractors on the performance of ADHD participants and typically-developing (TD) controls, and (4) compare the two measures on cognitive absorption...
June 3, 2016: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/27178061/the-influence-of-methylphenidate-on-hyperactivity-and-attention-deficits-in-children-with-adhd-a-virtual-classroom-test
#3
A Mühlberger, K Jekel, T Probst, M Schecklmann, A Conzelmann, M Andreatta, A A Rizzo, P Pauli, M Romanos
OBJECTIVE: This study compares the performance in a continuous performance test within a virtual reality classroom (CPT-VRC) between medicated children with ADHD, unmedicated children with ADHD, and healthy children. METHOD: N = 94 children with ADHD (n = 26 of them received methylphenidate and n = 68 were unmedicated) and n = 34 healthy children performed the CPT-VRC. Omission errors, reaction time/variability, commission errors, and body movements were assessed...
May 13, 2016: Journal of Attention Disorders
https://www.readbyqxmd.com/read/25682472/postnatal-arsenic-exposure-and-attention-impairment-in-school-children
#4
Miguel Rodríguez-Barranco, Fernando Gil, Antonio F Hernández, Juan Alguacil, Andres Lorca, Ramón Mendoza, Inmaculada Gómez, Isabel Molina-Villalba, Beatriz González-Alzaga, Clemente Aguilar-Garduño, Diane S Rohlman, Marina Lacasaña
Over the last few decades there has been an increased concern about the health risks from exposure to metallic trace elements, including arsenic, because of their potential neurotoxic effects on the developing brain. This study assessed whether urinary arsenic (UA) levels are associated with attention performance and Attention-Deficit/Hyperactivity Disorder (ADHD) in children living in an area with high industrial and mining activities in Southwestern Spain. A cross-sectional study was conducted on 261 children aged 6-9 years...
January 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/25570771/brain-computer-interface-using-p300-and-virtual-reality-a-gaming-approach-for-treating-adhd
#5
Darius Adam Rohani, Helge B D Sorensen, Sadasivan Puthusserypady
This paper presents a novel brain-computer interface (BCI) system aiming at the rehabilitation of attention-deficit/hyperactive disorder in children. It uses the P300 potential in a series of feedback games to improve the subjects' attention. We applied a support vector machine (SVM) using temporal and template-based features to detect these P300 responses. In an experimental setup using five subjects, an average error below 30% was achieved. To make it more challenging the BCI system has been embedded inside an immersive 3D virtual reality (VR) classroom with simulated distractions, which was created by combining a low-cost infrared camera and an "off-axis perspective projection" algorithm...
2014: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/23638628/aula-virtual-reality-test-as-an-attention-measure-convergent-validity-with-conners-continuous-performance-test
#6
Unai Díaz-Orueta, Cristina Garcia-López, Nerea Crespo-Eguílaz, Rocío Sánchez-Carpintero, Gema Climent, Juan Narbona
The majority of neuropsychological tests used to evaluate attention processes in children lack ecological validity. The AULA Nesplora (AULA) is a continuous performance test, developed in a virtual setting, very similar to a school classroom. The aim of the present study is to analyze the convergent validity between the AULA and the Continuous Performance Test (CPT) of Conners. The AULA and CPT were administered correlatively to 57 children, aged 6-16 years (26.3% female) with average cognitive ability (IQ mean = 100...
2014: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/22269913/impact-of-time-on-task-on-adhd-patient-s-performances-in-a-virtual-classroom
#7
Stéphanie Bioulac, Stéphanie Lallemand, Albert Rizzo, Pierre Philip, Colette Fabrigoule, Manuel Pierre Bouvard
BACKGROUND: Use of virtual reality tool is interesting for the evaluation of Attention Deficit/Hyperactivity Disorder (ADHD) patients. The virtual environment offers the opportunity to administer controlled task like the typical neuropsychological tools, but in an environment much more like standard classroom. Previous studies showed that a virtual classroom was able to distinguish performances of children with and without ADHD, but the evolution of performances over time has not been explored...
September 2012: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/21854630/virtual-environment-to-quantify-the-influence-of-colour-stimuli-on-the-performance-of-tasks-requiring-attention
#8
Alessandro P Silva, Annie F Frère
BACKGROUND: Recent studies indicate that the blue-yellow colour discrimination is impaired in ADHD individuals. However, the relationship between colour and performance has not been investigated. This paper describes the development and the testing of a virtual environment that is capable to quantify the influence of red-green versus blue-yellow colour stimuli on the performance of people in a fun and interactive way, being appropriate for the target audience. METHODS: An interactive computer game based on virtual reality was developed to evaluate the performance of the players...
2011: Biomedical Engineering Online
https://www.readbyqxmd.com/read/21088430/virtual-reality-in-pediatric-neurorehabilitation-attention-deficit-hyperactivity-disorder-autism-and-cerebral-palsy
#9
REVIEW
Michelle Wang, Denise Reid
This paper presents the current status and use of virtual reality (VR) for children with attention deficit hyperactivity disorder (ADHD), autism and cerebral palsy. This literature review explores how VR systems have been used as treatment tools to address the primary impairments of these disorders. Three major classes of VR display systems are identified that can be characterized by the type of human-computer interaction provided: (1) feedback-focused interaction, (2) gesture-based interaction, and (3) haptic-based interaction...
2011: Neuroepidemiology
https://www.readbyqxmd.com/read/20422835/-the-utility-of-a-continuous-performance-test-embedded-in-virtual-reality-in-measuring-the-effectiveness-of-mph-treatment-in-boys-with-adhd
#10
Liron Shriki, Merav Weizer, Yehuda Pollak, Patricia L Weiss, Albert A Rizzo, Varda Gross-Tsur
BACKGROUND: Continuous performance tasks (CPT) are popular in the diagnostic process of attention deficit hyperactivity disorder (ADHD), providing an objective measure of attention for a disorder with otherwise subjective criteria. AIMS: The study aimed to: 1) examine whether the VR-CPT is sensitive to methylphenidate (MPH); 2) assess how the virtual reality (VR) environment is experienced. METHODS: Twenty boys, 9-17 years, with ADHD underwent 3 CPTs: VR-CPT, the same CPT without VR (no VR-CPT) and the Test of Variables of Attention (T...
January 2010: Harefuah
https://www.readbyqxmd.com/read/20414157/methylphenidate-effect-in-children-with-adhd-can-be-measured-by-an-ecologically-valid-continuous-performance-test-embedded-in-virtual-reality
#11
Yehuda Pollak, Hanan Barhoum Shomaly, Patrice L Weiss, Albert A Rizzo, Varda Gross-Tsur
BACKGROUND: Continuous performance tasks (CPTs) embedded in a virtual reality (VR) classroom environment have been shown to be a sensitive and user-friendly assessment tool to detect cognitive deficits related to attention-deficit/hyperactivity disorder (ADHD). The aim of the current study was to compare the performance of children with ADHD on a VR-CPT while on and off treatment with methylphenidate (MPH) and to compare the VR-CPT to a currently used CPT, Test of Variables of Attention (TOVA)...
February 2010: CNS Spectrums
https://www.readbyqxmd.com/read/19194324/the-utility-of-a-continuous-performance-test-embedded-in-virtual-reality-in-measuring-adhd-related-deficits
#12
Yehuda Pollak, Patricia L Weiss, Albert A Rizzo, Merav Weizer, Liron Shriki, Ruth S Shalev, Varda Gross-Tsur
OBJECTIVE: Continuous performance tasks (CPT) are popular in the diagnostic process of Attention Deficit/Hyperactivity Disorder (ADHD), providing an objective measure of attention for a disorder with otherwise subjective criteria. Aims of the study were to: (1) compare the performance of children with ADHD on a CPT embedded within a virtual reality classroom (VR-CPT) to the currently used Test of Variables of Attention (TOVA) CPT, and (2) assess how the VR environment is experienced. METHODS: Thirty-seven boys, 9 to 17 years, with (n = 20) and without ADHD (n = 17) underwent 3 CPT's: VR-CPT, the same CPT without VR (No VR-CPT) and the TOVA...
February 2009: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/18608217/distractibility-in-attention-deficit-hyperactivity-disorder-adhd-the-virtual-reality-classroom
#13
Rebecca Adams, Paul Finn, Elisabeth Moes, Kathleen Flannery, Albert Skip Rizzo
Nineteen boys aged 8 to 14 with a diagnosis of ADHD and 16 age-matched controls were compared in a virtual reality (VR) classroom version of a continuous performance task (CPT), with a second standard CPT presentation using the same projection display dome system. The Virtual Classroom included simulated "real-world" auditory and visual distracters. Parent ratings of attention, hyperactivity, internalizing problems, and adaptive skills on the Behavior Assessment System for Children (BASC) Monitor for ADHD confirmed that the ADHD children had more problems in these areas than controls...
March 2009: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/18294083/rebound-effects-with-long-acting-amphetamine-or-methylphenidate-stimulant-medication-preparations-among-adolescent-male-drivers-with-attention-deficit-hyperactivity-disorder
#14
RANDOMIZED CONTROLLED TRIAL
Daniel J Cox, Melissa Moore, Roger Burket, R Lawrence Merkel, Amori Yee Mikami, Boris Kovatchev
This study investigated whether OROS methylphenidate (OROS MPH, Concerta) or extended-release mixed amphetamine salts (se-AMPH ER, Adderall XR) were associated with worsening of driving performance, or drug rebound, relative to placebo 16-17 hours post-ingestion. Nineteen male adolescent drivers aged 17-19 with attention-deficit/hyperactivity disorder (ADHD) were compared on a virtual reality driving simulator and an on-road drive after taking 72 mg of OROS MPH, 30 mg of se-AMPH ER, or placebo. Medication was taken at 08:00 in a randomized, double-blind, placebo-controlled, crossover study...
February 2008: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/17564852/a-controlled-clinical-comparison-of-attention-performance-in-children-with-adhd-in-a-virtual-reality-classroom-compared-to-standard-neuropsychological-methods
#15
COMPARATIVE STUDY
Thomas D Parsons, Todd Bowerly, J Galen Buckwalter, Albert A Rizzo
In this initial pilot study, a controlled clinical comparison was made of attention perforance in children with attention deficit-hyperactivity disorder (ADHD) in a virtual reality (VR) classroom. Ten boys diagnosed with ADHD and ten normal control boys participated in the study. Groups did not significantly differ in mean age, grade level, ethnicity, or handedness. No participants reported simulator sickness following VR exposure. Children with ADHD exhibited more omission errors, commission errors, and overall body movement than normal control children in the VR classroom...
July 2007: Child Neuropsychology: a Journal on Normal and Abnormal Development in Childhood and Adolescence
https://www.readbyqxmd.com/read/17242426/a-pilot-study-of-the-effects-of-atomoxetine-on-driving-performance-in-adults-with-adhd
#16
RANDOMIZED CONTROLLED TRIAL
Russell A Barkley, Deborah L Anderson, Markus Kruesi
OBJECTIVE: There is a high risk of vehicular crashes, traffic citations, and poorer driving performance in adults with ADHD. This pilot study examines the value of a new nonstimulant (atomoxetine) for improving the driving performance of adults with ADHD. METHOD: Atomoxetine (1.2 mg/kg daily for 3 weeks) and a placebo are studied on 18 adults with ADHD (M age = 37 years) using ratings of ADHD symptoms, impairment, and safe driving behavior; a virtual reality driving simulator; and ratings of simulator performance...
February 2007: Journal of Attention Disorders
https://www.readbyqxmd.com/read/16597216/road-crossing-safety-in-virtual-reality-a-comparison-of-adolescents-with-and-without-adhd
#17
COMPARATIVE STUDY
Tamera A Clancy, Julia J Rucklidge, Dean Owen
This study investigated the potential accident-proneness of adolescents with attention deficit hyperactivity disorder (ADHD) in a hazardous road-crossing environment. An immersive virtual reality traffic gap-choice task was used to determine whether ADHD adolescents show more unsafe road-crossing behavior than controls. Participants (ages 13 to 17) were identified with (n = 24) or without (n = 24) ADHD according to a standardized protocol (Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version and Conners' Scales), with equal number of boys (n = 12) and girls (n = 12) in each group...
June 2006: Journal of Clinical Child and Adolescent Psychology
https://www.readbyqxmd.com/read/16460224/effects-of-two-doses-of-alcohol-on-simulator-driving-performance-in-adults-with-attention-deficit-hyperactivity-disorder
#18
COMPARATIVE STUDY
Russell A Barkley, Kevin R Murphy, Trisha O'Connell, Deborah Anderson, Daniel F Connor
Prior studies have documented greater impairments in driving performance and greater alcohol consumption among adults with attention-deficit/hyperactivity disorder (ADHD). This study examined whether alcohol consumption produces a differentially greater impairment in driving among adults with ADHD in comparison to a community control group. The present study compared 50 adults with ADHD (mean age 33 years) and 40 control adults (mean age 29 years) on the effects of 2 single, acute doses of alcohol (0.04 and 0...
January 2006: Neuropsychology
https://www.readbyqxmd.com/read/16400254/a-virtual-reality-scenario-for-all-seasons-the-virtual-classroom
#19
Albert A Rizzo, Todd Bowerly, J Galen Buckwalter, Dean Klimchuk, Roman Mitura, Thomas D Parsons
Treatment and rehabilitation of the cognitive, psychological, and motor sequelae of central nervous system dysfunction often relies on assessment instruments to inform diagnosis and to track changes in clinical status. Typically, these assessments employ paper-and-pencil psychometrics, hands-on analog/computer tests, and rating of behavior within the context of real-world functional environments. Virtual reality offers the option to produce and distribute identical "standard" simulation environments in which performance can be measured and rehabilitated...
January 2006: CNS Spectrums
https://www.readbyqxmd.com/read/16110052/accuracy-of-self-evaluation-in-adults-with-adhd-evidence-from-a-driving-study
#20
Laura E Knouse, Catherine L Bagwell, Russell A Barkley, Kevin R Murphy
Research on children with ADHD indicates an association with inaccuracy of self-appraisal. This study examines the accuracy of self-evaluations in clinic-referred adults diagnosed with ADHD. Self-assessments and performance measures of driving in naturalistic settings and on a virtual-reality driving simulator are used to assess accuracy of self-evaluations. The group diagnosed with ADHD (n= 44) has a higher rate of collisions, speeding tickets, and total driving citations in their driving history; report less use of safe driving behaviors in naturalistic settings; and use fewer safe driving behaviors in the simulator than the community comparison group (n= 44)...
May 2005: Journal of Attention Disorders
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