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https://www.readbyqxmd.com/read/29717910/treating-adhd-with-suggestion-neurofeedback-and-placebo-therapeutics
#1
Robert T Thibault, Samuel Veissière, Jay A Olson, Amir Raz
OBJECTIVE: We propose that clinicians can use suggestion to help treat conditions such as ADHD. METHODS: We use EEG neurofeedback as a case study, alongside evidence from a recent pilot experiment utilizing a sham MRI scanner to highlight the therapeutic potential of suggestion-based treatments. RESULTS: The medical literature demonstrates that many practitioners already prescribe treatments that hardly outperform placebo comparators. Moreover, the sham MRI experiment showed that, even with full disclosure of the procedure, suggestion alone can reduce the symptomatology of ADHD...
April 1, 2018: Journal of Attention Disorders
https://www.readbyqxmd.com/read/29706908/event-related-potential-erp-correlates-of-performance-monitoring-in-adults-with-attention-deficit-hyperactivity-disorder-adhd
#2
Lynn Marquardt, Heike Eichele, Astri J Lundervold, Jan Haavik, Tom Eichele
Introduction: Attention-deficit hyperactivity disorder (ADHD) is one of the most frequent neurodevelopmental disorders in children and tends to persist into adulthood. Evidence from neuropsychological, neuroimaging, and electrophysiological studies indicates that alterations of error processing are core symptoms in children and adolescents with ADHD. To test whether adults with ADHD show persisting deficits and compensatory processes, we investigated performance monitoring during stimulus-evaluation and response-selection, with a focus on errors, as well as within-group correlations with symptom scores...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29658934/using-brain-activation-nir-heg-q-eeg-and-execution-measures-cpts-in-a-adhd-assessment-protocol
#3
Debora Areces, Marisol Cueli, Trinidad García, Paloma González-Castro, Celestino Rodríguez
Attention Deficit Hyperactivity Disorder (ADHD) is a problem that impacts academic performance and has serious consequences that result in difficulties in scholastic, social and familial contexts. One of the most common problems in the identification of this disorder relates to the apparent over diagnosis of the disorder due to the absence of global protocols for assessment. The research group of School Learning, Difficulties and Academic Performance (ADIR) from the University of Oviedo, has developed a complete protocol that suggests the existence of certain patterns of cortical activation and executive control for identifying ADHD more objectively...
April 1, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29588970/prevalence-risk-factors-and-neurobehavioral-comorbidities-of-epilepsy-in-kenyan-children
#4
Charles J Kind, Charles R J C Newton, Symon M Kariuki
Objective: To investigate the prevalence, risk factors, clinical features, and neurobehavioral comorbidities of epilepsy and acute symptomatic seizures in school-aged children in Kilifi, Kenya. Methods: Randomly selected children (N = 11,223) were screened for epilepsy and other neurodevelopmental disorders. Those who screened positive were invited for further clinical, electroencephalographic (EEG), and neuropsychological evaluations. Prevalence was measured by dividing cases by screened population, providing Agresti-Coull confidence intervals (CIs)...
December 2017: Epilepsia Open
https://www.readbyqxmd.com/read/29581452/semi-automated-biomarker-discovery-from-pharmacodynamic-effects-on-eeg-in-adhd-rodent-models
#5
Tatsuya Yokota, Zbigniew R Struzik, Peter Jurica, Masahito Horiuchi, Shuichi Hiroyama, Junhua Li, Yuji Takahara, Koichi Ogawa, Kohei Nishitomi, Minoru Hasegawa, Andrzej Cichocki
We propose a novel semi-automatic approach to design biomarkers for capturing pharmacodynamic effects induced by pharmacological agents on the spectral power of electroencephalography (EEG) recordings. We apply this methodology to investigate the pharmacodynamic effects of methylphenidate (MPH) and atomoxetine (ATX) on attention deficit/hyperactivity disorder (ADHD), using rodent models. We inject the two agents into the spontaneously hypertensive rat (SHR) model of ADHD, the Wistar-Kyoto rat (WKY), and the Wistar rat (WIS), and record their EEG patterns...
March 26, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29560310/neural-mechanisms-underlying-successful-and-deficient-multi-component-behavior-in-early-adolescent-adhd
#6
Annet Bluschke, Krutika Gohil, Maxi Petzold, Veit Roessner, Christian Beste
Attention Deficit Hyperactivity Disorder (ADHD) is a disorder affecting cognitive control. These functions are important to achieve goals when different actions need to be executed in close succession. This type of multi-component behavior, which often further requires the processing of information from different modalities, is important for everyday activities. Yet, possible changes in neurophysiological mechanisms have not been investigated in adolescent ADHD. We examined N = 31 adolescent ADHD patients and N = 35 healthy controls (HC) in two Stop-Change experiments using either uni-modal or bi-modal stimuli to trigger stop and change processes...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29518704/distraction-by-salient-stimuli-in-adults-with-attention-deficit-hyperactivity-disorder-evidence-for-the-role-of-task-difficulty-in-bottom-up-and-top-down-processing
#7
Alexander Schneidt, Aiste Jusyte, Karsten Rauss, Michael Schönenberg
The cognitive mechanisms of increased distractibility in attention-deficit/hyperactivity disorder (ADHD) are poorly understood. The current study investigated the influence of two major modulating factors (emotional saliency, task difficulty) on behavioral and electrophysiological parameters underlying distractibility in ADHD. In addition, the attentional focus (indirect and direct processing of distractors) was examined. Thirty-six adults with ADHD and 37 healthy controls completed two experimental tasks while electroencephalography (EEG) data was collected...
April 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29514416/working-memory-alpha-beta-band-oscillatory-signatures-in-adolescents-and-young-adults
#8
Nowell Zammit, Owen Falzon, Kenneth Camilleri, Richard Muscat
The timing of neural activity is an intriguing way of exposing behaviorally relevant neural activity, as neural populations exploit transient windows of synchronized activations to exchange dynamic communications in the service of various cognitive operations. The link between neural synchrony and working memory (WM) has been supported at the theoretical and empirical level. However, findings have also shown that WM encoding is also related to significant alpha-beta desynchronization. These findings have been primarily recorded during subsequent memory effect paradigms that compare correct with incorrect encoding trials...
March 7, 2018: European Journal of Neuroscience
https://www.readbyqxmd.com/read/29493639/-neurofeedback-in-parkinson-s-disease-technologies-in-speech-and-language-therapy
#9
Valentina Lavermicocca, Anna Rita Dellomonaco, Angela Tedesco, Marilina Notarnicola, Roberta Di Fede, Piero Paolo Battaglini
Neurofeedback (NF) is a form of biofeedback based on the self-modulation of brain activity; it aims to enhance mental and behavioral performances. The user modifies his brain functions thanks to EEG-mediated self-regulation and therapist's guidance. Recent advances in Brain-Computer Interfaces (BCI) have provided new evidence on the effectiveness of NF in reinforcing cognitive functions expecially in children with ADHD. The applications on adults with cognitive deficits are still few. The study aims to investigate the possible effect of NF techniques on cognitive performance of patients with Parkinson's disease (PD) in terms of changes in scores at the neurocognitive assessment...
February 2018: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/29457912/decreased-resting-gamma-activity-in-adult-attention-deficit-hyperactivity-disorder
#10
László Tombor, Brigitta Kakuszi, Szilvia Papp, János Réthelyi, István Bitter, Pál Czobor
OBJECTIVES: To delineate task-free gamma activity in adult ADHD and healthy control subjects based on high-density EEG recordings. Relationship of gamma activity with symptom severity was also examined, since gamma activity is considered to be an index of network functions in the brain that underlie higher-order cognitive processes. METHODS: Spontaneous EEG was recorded in adult ADHD subjects (N = 42; 25 methylphenidate-naïve and 17 on methylphenidate treatment) and controls (N = 59) with eyes open...
March 5, 2018: World Journal of Biological Psychiatry
https://www.readbyqxmd.com/read/29449806/monitoring-attention-in-adhd-with-an-easy-to-use-electrophysiological-index
#11
Goded Shahaf, Uri Nitzan, Galit Erez, Shlomo Mendelovic, Yuval Bloch
Attention deficit hyperactivity disorder (ADHD) involves characteristic electroencephalographic (EEG) activity. We developed a single-channel EEG marker for attention: the Brain Engagement Index (BEI'). In this study, we evaluated the use of BEI' for distinguishing between ADHD patients and controls, and for monitoring the effect of pharmacological treatment on ADHD patients. The BEI' values of 20 ADHD patients and 10 controls were measured using a 1-min auditory oddball paradigm and a continuous performance test (CPT) task...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29432505/the-use-of-eeg-biofeedback-neurofeedback-in-psychiatric-rehabilitation
#12
REVIEW
Renata Markiewcz
The aim of the systematic review was to evaluate the use of EEG Biofeedback/Neurofeedback in patients treated for mental disorders. The review covered publications analyzing influences and effects of therapy in patients receiving psychiatric treatment based on EEG Biofeedback/Neurofeedback. Selection of publications was made by searching PubMed and Scopus databases. 328 records concerning applications of the presented method were identified in total, including 84 records for patients diagnosed with mental disorders...
December 30, 2017: Psychiatria Polska
https://www.readbyqxmd.com/read/29422636/childhood-epilepsy-and-adhd-comorbidity-in-an-indian-tertiary-medical-center-outpatient-population
#13
Anita Choudhary, Sheffali Gulati, Rajesh Sagar, Naveen Sankhyan, Kam Sripada
This study aimed to assess the prevalence of Attention Deficit Hyperactivity Disorder (ADHD) and its characteristics and risk factors in children with epilepsy at a tertiary medical center in New Delhi. Children with active epilepsy, aged 6 to 12 years, were assessed for ADHD using DSM-IV-TR criteria. Epilepsy and psychiatric characteristics, sociodemographic indicators, and use of antiepileptic drugs were analyzed for differences between the ADHD and non-ADHD groups. Among the 73 children with epilepsy, 23% (n = 17) had comorbid ADHD, of whom 59% (n = 10) had predominantly inattentive type, 35% (n = 6) combined type, and 6% (n = 1) predominantly hyperactive-impulsive type...
February 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29403368/on-the-efficiency-of-individualized-theta-beta-ratio-neurofeedback-combined-with-forehead-emg-training-in-adhd-children
#14
Olga M Bazanova, Tibor Auer, Elena A Sapina
Background: Neurofeedback training (NFT) to decrease the theta/beta ratio (TBR) has been used for treating hyperactivity and impulsivity in attention deficit hyperactivity disorder (ADHD); however, often with low efficiency. Individual variance in EEG profile can confound NFT, because it may lead to influencing non-relevant activity, if ignored. More importantly, it may lead to influencing ADHD-related activities adversely, which may even result in worsening ADHD symptoms. Electromyogenic (EMG) signal resulted from forehead muscles can also explain the low efficiency of the NFT in ADHD from both practical and psychological point-of-view...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29391481/neurophysiological-mechanisms-of-interval-timing-dissociate-inattentive-and-combined-adhd-subtypes
#15
Annet Bluschke, Jacqueline Schuster, Veit Roessner, Christian Beste
It is far from conclusive what distinguishes the inattentive (ADD) and the combined (ADHD-C) subtype of ADHD on the neuronal level. Theoretical considerations suggest that especially interval timing processes may dissociate these subtypes from each other. Combining high-density EEG recordings with source localization analyses, we examine whether there are ADHD-subtype specific modulations of neurophysiological processes subserving interval timing in matched groups of ADD (n = 16), ADHD-C (n = 16) and controls (n = 16)...
February 1, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29366980/combining-behavior-and-eeg-analysis-for-exploration-of-dynamic-effects-of-adhd-treatment-in-animal-models
#16
Peter Jurica, Zbigniew R Struzik, Junhua Li, Masahito Horiuchi, Shuichi Hiroyama, Yuji Takahara, Kohei Nishitomi, Koichi Ogawa, Andrzej Cichocki
BACKGROUND: We analyze the dynamics of rodent EEG amplitude in an experiment accompanied by video recordings. Brain activity of animals is commonly acquired together with a video of behavior, but recordings are rarely combined in analysis. The data acquired is most commonly analyzed separately. To our knowledge, no study has used behavior to improve the analysis of EEG waveforms, specifically for artifact removal - other than through manual editing. COMPARISON WITH EXISTING METHOD(S): We explore two approaches: a traditional approach that relies on data preprocessing and artifact rejection by an expert; and an alternative approach that combines analysis of EEG with behavior extracted from video recordings...
March 15, 2018: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/29343456/eeg-dynamics-and-neural-generators-in-implicit-navigational-image-processing-in-adults-with-adhd
#17
A Leroy, G Petit, D Zarka, A M Cebolla, E Palmero-Soler, J Strul, B Dan, P Verbanck, G Cheron
In contrast to childhood ADHD that is characterized by inattention, impulsivity and hyperactivity, most adults with ADHD predominantly exhibit inattention. We used a new oddball paradigm using implicit navigational images and analysed EEG dynamics with swLORETA inverse modelling of the evoked potential generators to study cortical processing in adults with ADHD and age-matched controls. In passive observation, we demonstrated that P350 amplitude, alpha-beta oscillation event-related synchronization (ERS) anticipation, and beta event-related desynchronization (ERD) were significantly smaller in ADHD...
January 14, 2018: Neuroscience
https://www.readbyqxmd.com/read/29291475/brain-arousal-regulation-in-adults-with-attention-deficit-hyperactivity-disorder-adhd
#18
Maria Strauß, Christine Ulke, Madlen Paucke, Jue Huang, Nicole Mauche, Christian Sander, Tetyana Stark, Ulrich Hegerl
The main aim of the current study was to test the hypothesis that adult patients with attention-deficit/hyperactivity disorder (ADHD) have less stable brain arousal regulation than healthy controls. We objectively assessed brain arousal regulation using the Vigilance Algorithm Leipzig (VIGALL 2.1) to analyze 15-min resting EEG data of thirty-three ADHD patients and thirty-five matched controls. Based on automatically classified 1-s segments we computed mean EEG-vigilance (indexing arousal level) and arousal stability score (indexing arousal regulation)...
March 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29261133/eeg-dynamics-of-a-go-nogo-task-in-children-with-adhd
#19
Simon Baijot, Carlos Cevallos, David Zarka, Axelle Leroy, Hichem Slama, Cecile Colin, Nicolas Deconinck, Bernard Dan, Guy Cheron
BACKGROUND: Studies investigating event-related potential (ERP) evoked in a Cue-Go/NoGo paradigm have shown lower frontal N1, N2 and central P3 in children with attention-deficit/hyperactivity disorder (ADHD) compared to typically developing children (TDC). However, the electroencephalographic (EEG) dynamics underlying these ERPs remain largely unexplored in ADHD. METHODS: We investigate the event-related spectral perturbation and inter-trial coherence linked to the ERP triggered by visual Cue-Go/NoGo stimuli, in 14 children (7 ADHD and 7 TDC) aged 8 to 12 years...
December 20, 2017: Brain Sciences
https://www.readbyqxmd.com/read/29258410/different-cortical-source-activation-patterns-in-children-with-attention-deficit-hyperactivity-disorder-during-a-time-reproduction-task
#20
Shiva Khoshnoud, Mousa Shamsi, Mohammad Ali Nazari, Scott Makeig
Several neurocognitive studies have indicated that children with attention-deficit/hyperactivity disorder (ADHD) exhibit cognitive deficits in perceptual timing functions; however, only a few electroencephalographic studies have investigated their time reproduction abilities. In the present research, 15 children with ADHD were studied along with 19 age-matched control subjects (aged 7-11 years) as they attempted to reproduce shorter (1000 ms) and longer (2200 ms) time intervals. Trial-mean event-related potential (ERP) and event-related spectral perturbation measures were used to compare the electroencephalography (EEG) source-level activity patterns of the ADHD and control subjects during the time-encoding and reproduction phases...
December 19, 2017: Journal of Clinical and Experimental Neuropsychology
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