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https://www.readbyqxmd.com/read/28286676/cerebellar-cathodal-transcranial-direct-stimulation-and-performance-on-a-verb-generation-task-a-replication-study
#1
K Spielmann, R van der Vliet, W M E van de Sandt-Koenderman, M A Frens, G M Ribbers, R W Selles, S van Vugt, J N van der Geest, P Holland
The role of the cerebellum in cognitive processing is increasingly recognized but still poorly understood. A recent study in this field applied cerebellar Transcranial Direct Current Stimulation (c-tDCS) to the right cerebellum to investigate the role of prefrontal-cerebellar loops in language aspects of cognition. Results showed that the improvement in participants' verbal response times on a verb generation task was facilitated immediately after cathodal c-tDCS, compared to anodal or sham c-tDCS. The primary aim of the present study is to replicate these findings and additionally to investigate possible longer term effects...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28088713/the-effects-of-utterance-timing-and-stimulation-of-left-prefrontal-cortex-on-the-production-of-referential-expressions
#2
Jennifer E Arnold, Nazbanou Nozari
We examined the relationship between the timing of utterance initiation and the choice of referring expressions, e.g., pronouns (it), zeros (…and went down), or descriptive NPs (the pink pentagon). We examined language production in healthy adults, and used anodal transcranial direct current stimulation (tDCS) to test the involvement of the left prefrontal cortex (PFC) in the timing of utterance production and the selection of reference forms in a discourse context. Twenty-two subjects (11 anodal, 11sham) described fast-paced actions, e...
March 2017: Cognition
https://www.readbyqxmd.com/read/28069925/cerebellar-tdcs-modulates-neural-circuits-during-semantic-prediction-a-combined-tdcs-fmri-study
#3
Anila M D'Mello, Peter E Turkeltaub, Catherine J Stoodley
It has been proposed that the cerebellum acquires internal models of mental processes that enable prediction, allowing for the optimization of behavior. In language, semantic prediction speeds speech production and comprehension. Right cerebellar lobules VI and VII (including Crus I/II) are engaged during a variety of language processes and are functionally connected with cerebral cortical language networks. Further, right posterolateral cerebellar neuromodulation modifies behavior during predictive language processing...
February 8, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28062255/differential-effects-of-bihemispheric-and-unihemispheric-transcranial-direct-current-stimulation-in-young-and-elderly-adults-in-verbal-learning
#4
Valentina Fiori, Michael Nitsche, Luigi Iasevoli, Gabriella Cucuzza, Carlo Caltagirone, Paola Marangolo
For the past few years, the potential of transcranial direct current stimulation (tDCS) for the treatment of several pathologies has been investigated. In the language domain, several studies, in healthy and brain-damaged populations, have already shown that tDCS is effective in enhancing naming, repetition and semantic word generation. In those studies, different tDCS electrode configurations have been tested, however, a direct comparison between different montages in verbal learning has never been conducted...
March 15, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28003159/both-anodal-and-cathodal-transcranial-direct-current-stimulation-improves-semantic-processing
#5
Sabrina Brückner, Thomas Kammer
Transcranial direct current stimulation (tDCS) is a common method to modulate cortical activity. Anodal tDCS is usually associated with an enhancement of the stimulated brain area, whereas cathodal tDCS is often described as inhibitory brain stimulation method. Our aim was to investigate whether this canonical assumption derived from the motor system could be transferred to the semantic system. Three groups with 20 healthy subjects each were stimulated at Wernicke's area with either anodal, cathodal or sham tDCS...
December 18, 2016: Neuroscience
https://www.readbyqxmd.com/read/27997958/use-of-tdcs-in-aphasia-rehabilitation-a-systematic-review-of-the-behavioral-interventions-implemented-with-noninvasive-brain-stimulation-for-language-recovery
#6
Elizabeth E Galletta, Peggy Conner, Amy Vogel-Eyny, Paola Marangolo
Purpose: The purpose of this article is to review the behavioral treatments used in aphasia rehabilitation research that have been combined with transcranial direct current stimulation (tDCS). Although tDCS in aphasia treatment has shown promise, the results have not been conclusive, and their interpretation is further compounded by the heterogeneity of study characteristics. Because implementing a behavioral task during brain stimulation has been shown to be pivotal to the adjuvant effects of tDCS, we analyze the behavioral treatments that have been paired with tDCS...
December 1, 2016: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/27912107/limits-to-tdcs-effects-in-language-failures-to-modulate-word-production-in-healthy-participants-with-frontal-or-temporal-tdcs
#7
Samuel J Westwood, Andrew Olson, R Chris Miall, Raffaele Nappo, Cristina Romani
Transcranial direct current stimulation (tDCS) is a method of non-invasive brain stimulation widely used to modulate cognitive functions. Recent studies, however, suggests that effects are unreliable, small and often non-significant at least when stimulation is applied in a single session to healthy individuals. We examined the effects of frontal and temporal lobe anodal tDCS on naming and reading tasks and considered possible interactions with linguistic activation and selection mechanisms as well as possible interactions with item difficulty and participant individual variability...
January 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/27859982/transcranial-direct-current-stimulation-effects-on-neural-processing-in-post-stroke-aphasia
#8
Robert Darkow, Andrew Martin, Anna Würtz, Agnes Flöel, Marcus Meinzer
Non-invasive transcranial direct current stimulation (tDCS) can enhance recovery after stroke. However, fundamental knowledge about how tDCS impacts neural processing in the lesioned human brain is currently lacking. In the present study, it was investigated how tDCS modulates brain function in patients with post-stroke language impairment (aphasia). In a cross-over, randomized trial, patients named pictures of common objects during functional magnetic resonance imaging (fMRI). Concurrently, excitatory (anodal-) or sham-tDCS (1 mA, 20 min, or 30 s, respectively) was administered to the left primary motor cortex, a montage with demonstrated potential to improve aphasic language...
November 11, 2016: Human Brain Mapping
https://www.readbyqxmd.com/read/27858095/-new-aspects-of-neurorehabilitation-motor-and-language
#9
REVIEW
J Liepert, C Breitenstein
Advancements in medical care over the last decades have contributed to a continuous decline in immediate post-stroke mortality. The flipside of this development is that patients surviving the initial stroke are forced to live with sometimes extreme functional motor and/or language limitations for the remaining life span. The following overview presents evidence-based neurorehabilitative interventions to promote motor and language recovery in the acute and chronic post-stroke stages. Therapeutic approaches comprise intensive training, neuropharmacological drugs and non-invasive brain stimulation techniques, such as transcranial magnetic stimulation (TMS) or direct current stimulation (tDCS)...
December 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27830094/adaptive-plasticity-in-the-healthy-language-network-implications-for-language-recovery-after-stroke
#10
REVIEW
Gesa Hartwigsen
Across the last three decades, the application of noninvasive brain stimulation (NIBS) has substantially increased the current knowledge of the brain's potential to undergo rapid short-term reorganization on the systems level. A large number of studies applied transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) in the healthy brain to probe the functional relevance and interaction of specific areas for different cognitive processes. NIBS is also increasingly being used to induce adaptive plasticity in motor and cognitive networks and shape cognitive functions...
2016: Neural Plasticity
https://www.readbyqxmd.com/read/27774217/a-pragmatic-analysis-of-the-regulation-of%C3%A2-consumer-transcranial-direct-current-stimulation-tdcs-devices-in-the-united-states
#11
Anna Wexler
Several recent articles have called for the regulation of consumer transcranial direct current stimulation (tDCS) devices, which provide low levels of electrical current to the brain. However, most of the discussion to-date has focused on ethical or normative considerations; there has been a notable absence of scholarship regarding the actual legal framework in the United States. This article aims to fill that gap by providing a pragmatic analysis of the consumer tDCS market and relevant laws and regulations...
November 2015: Journal of Law and the Biosciences
https://www.readbyqxmd.com/read/27615184/-transcranial-direct-current-stimulation-new-clinical-roadmaps-for-psychiatric-research
#12
Alexandre Heeren, Charlotte Coussement, Élisabeth Colon
Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that has undergone intensive research over the past decade with promising results. tDCS is based on the application of weak, direct current over the scalp, leading to cortical hypo- or hyperpolarization according to the specified parameters. Recent studies have shown that tDCS is able to induce potent changes in cortical excitability as well as to elicit long-lasting modifications in brain activity. Over the last decade, tDCS physiological mechanisms of action have been intensively investigated...
August 2016: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/27522537/transcranial-direct-current-stimulation-for-the-treatment-of-primary-progressive-aphasia-an-open-label-pilot-study
#13
Felix Gervits, Sharon Ash, H Branch Coslett, Katya Rascovsky, Murray Grossman, Roy Hamilton
Primary progressive aphasia (PPA) is a neurodegenerative condition characterized by gradual deterioration of language function. We investigated whether two weeks of daily transcranial direct current stimulation (tDCS) treatment would improve language abilities in six people with a non-fluent form of PPA. tDCS was applied in an unblinded trial at an intensity of 1.5mA for 20min/day over 10days. At the time of stimulation, patients were engaged in narrating one of several children's wordless picture stories. A battery of neuropsychological assessments was administered four times: at baseline, immediately following the 2-week stimulation period, and then 6-weeks and 12-weeks following the end of stimulation...
November 2016: Brain and Language
https://www.readbyqxmd.com/read/27484456/transcranial-direct-current-stimulation-in-post-stroke-sub-acute-aphasia-study-protocol-for-a-randomized-controlled-trial
#14
Kerstin Spielmann, W Mieke E van de Sandt-Koenderman, Majanka H Heijenbrok-Kal, Gerard M Ribbers
BACKGROUND: Transcranial direct current stimulation (tDCS) is a promising new technique to optimize the effect of regular Speech and Language Therapy (SLT) in the context of aphasia rehabilitation. The present study focuses on the effect of tDCS provided during SLT in the sub-acute stage after stroke. The primary aim is to evaluate the potential effect of tDCS on language functioning, specifically on word-finding, as well as generalization effects to verbal communication. The secondary aim is to evaluate its effect on social participation and quality of life, and its cost-effectiveness...
2016: Trials
https://www.readbyqxmd.com/read/27472845/modulating-transcallosal-and-intra-hemispheric-brain-connectivity-with-tdcs-implications-for-interventions-in-aphasia
#15
Xin Zheng, Weiying Dai, David C Alsop, Gottfried Schlaug
BACKGROUND/OBJECTIVE: Transcranial direct current stimulation (tDCS) can enhance or diminish cortical excitability levels depending on the polarity of the stimulation. One application of non-invasive brain-stimulation has been to modulate a possible inter-hemispheric disinhibition after a stroke. This disinhibition model has been developed mainly for the upper extremity motor system, but it is not known whether the language/speech-motor system shows a similar inter-hemispheric interaction...
July 25, 2016: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/27314871/transcranial-direct-current-stimulation-in-post-stroke-aphasia-and-primary-progressive-aphasia-current-knowledge-and-future-clinical-applications
#16
REVIEW
Rajani Sebastian, Kyrana Tsapkini, Donna C Tippett
BACKGROUND: The application of transcranial direct current stimulation (tDCS) in chronic post stroke aphasia is documented in a substantial literature, and there is some new evidence that tDCS can augment favorable language outcomes in primary progressive aphasia. Anodal tDCS is most often applied to the left hemisphere language areas to increase cortical excitability (increase the threshold of activation) and cathodal tDCS is most often applied to the right hemisphere homotopic areas to inhibit over activation in contralesional right homologues of language areas...
June 13, 2016: NeuroRehabilitation
https://www.readbyqxmd.com/read/27232953/cerebellar-tdcs-as-a-novel-treatment-for-aphasia-evidence-from-behavioral-and-resting-state-functional-connectivity-data-in-healthy-adults
#17
Peter E Turkeltaub, Mary K Swears, Anila M D'Mello, Catherine J Stoodley
BACKGROUND: Aphasia is an acquired deficit in the ability to communicate through language. Noninvasive neuromodulation offers the potential to boost neural function and recovery, yet the optimal site of neuromodulation for aphasia has yet to be established. The right posterolateral cerebellum is involved in multiple language functions, interconnects with left-hemisphere language cortices, and is crucial for optimization of function and skill acquisition, suggesting that cerebellar neuromodulation could enhance aphasia rehabilitation...
May 24, 2016: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/27194245/grey-matter-density-predicts-the-improvement-of-naming-abilities-after-tdcs-intervention-in-agrammatic-variant-of-primary-progressive-aphasia
#18
Maria Cotelli, Rosa Manenti, Donata Paternicò, Maura Cosseddu, Michela Brambilla, Michela Petesi, Enrico Premi, Roberto Gasparotti, Orazio Zanetti, Alessandro Padovani, Barbara Borroni
Agrammatic variant primary progressive aphasia is a neurodegenerative disorder specifically characterized by language deficits. A recent study has demonstrated a beneficial effect of transcranial direct current stimulation (tDCS) in combination with language training on naming accuracy in these patients. The aim of the study was to evaluate whether the improvement of naming accuracy after tDCS during language training was related to regional grey matter (GM) density. Eighteen avPPA patients underwent a brain magnetic resonance imaging before receiving a treatment that consisted of tDCS over the left dorsolateral prefrontal cortex during individualized language training (10 daily therapy sessions, 5 days per week from Monday to Friday)...
September 2016: Brain Topography
https://www.readbyqxmd.com/read/27167887/-non-invasive-brain-stimulation-in-neurology-transcranial-direct-current-stimulation-to-enhance-cognitive-functioning
#19
REVIEW
D Antonenko, A Flöel
Transcranial direct current stimulation (tDCS) has been successfully used in neuroscientific research to modulate cognitive functions. Recent studies suggested that improvement of behavioral performance is associated with tDCS-induced modulation of neuronal activity and connectivity. Thus, tDCS may also represent a promising tool for reconstitution of cognitive functions in the context of memory decline related to Alzheimer's disease or aphasia following stroke; however, evidence from randomized sham-controlled clinical trials is still scarce...
August 2016: Der Nervenarzt
https://www.readbyqxmd.com/read/27163249/fields-or-flows-a-comparative-metaanalysis-of-transcranial-magnetic-and-direct-current-stimulation-to-treat-post-stroke-aphasia
#20
Priyanka P Shah-Basak, Rachel Wurzman, Juliann B Purcell, Felix Gervits, Roy Hamilton
PURPOSE: Aphasia-acquired loss of the ability to understand or express language-is a common and debilitating neurological consequence of stroke. Evidence suggests that transcranial magnetic (TMS) or direct current stimulation (tDCS) can significantly improve language outcomes in patients with aphasia (PWA). However, the relative efficacy between TMS and tDCS has not yet been explored. Mechanistic and methodological differences, patient inclusion/exclusion criteria and experimental designs may influence observed treatment benefits...
May 2, 2016: Restorative Neurology and Neuroscience
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