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Kidney stones

Louise Stone
No abstract text is available yet for this article.
October 25, 2016: Nature Reviews. Urology
Rawan Al-Yousef, Ahmad Almarzouq, Saad Aldousari
INTRODUCTION AND OBJECTIVES: Ectopic pelvic kidneys with renal stones are challenging to treat. We report our experience in managing a case of ectopic pelvic kidney with a pelvic stone by robotic pyelolithotomy after failure of flexible ure¬teroscopy. MATERIALS AND METHODS: A 46-year old male with 2 months history of vague lower abdominal pain was found to have on Computed Tomography scan a left ectopic pelvic kidney with a 12mm stone in an anomalous renal pelvis...
October 20, 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
William E Haley, Felicity T Enders, Lisa E Vaughan, Ramila A Mehta, Maxton E Thoman, Terri J Vrtiska, Amy E Krambeck, John C Lieske, Andrew D Rule
OBJECTIVE: To determine whether there is a persistent decline in kidney function after the first kidney stone event. PATIENT AND METHODS: Incident symptomatic stone formers and age- and sex-matched controls underwent 2 study visits 90 days apart to assess kidney function, complete a survey, and have their medical records reviewed. Kidney function was compared between stone formers and controls adjusting for clinical, blood, and urine risk factors. RESULTS: There were 384 stone formers and 457 controls...
October 21, 2016: Mayo Clinic Proceedings
Ines van Dooren, Kenn Foubert, Sebastiaan Bijttebier, Mart Theunis, Stefaniya Velichkova, Magda Claeys, Luc Pieters, Vassiliki Exarchou, Sandra Apers
Stone diseases present a major health problem in the Western society, since both urinary and biliary stones occur with a relatively high prevalence of 10-12 % and 10-20 %, respectively, and demonstrate a high recurrence rate. At the moment treatment is mainly based on interventional procedures, or prophylactic and dissolution therapy. However, many of the current drugs cause severe side effects, and therefore, there is an increasing interest in natural medicines. At the moment no registered herbal medicinal products are available for treatment of gallstones...
October 24, 2016: Planta Medica
Francesca New, Bhaskar K Somani
PURPOSE OF REVIEW: The purpose of this study was to review the current evidence for quality of life (QOL) in patients with kidney stone disease (KSD). RECENT FINDINGS: A review of literature from inception to May 2016 for all prospective English language articles on QOL in patients with KSD was done. QOL studies post urological procedures or ureteric stents were excluded. Nine studies (1570 patients) were included of which most (n = 6) used the SF-36 QOL tool...
December 2016: Current Urology Reports
Riccardo Galli, Maria C Sighinolfi, Salvatore Micali, Eugenio Martorana, Marco Rosa, Alessando Mofferdin, Giampaolo Bianchi
BACKGROUND: Shock Wave Lithotripsy (SWL) for distal ureteral stones can be performed in prone or supine position. Our aim is to demonstrate the advantage of the supine transgluteal SWL approach for distal ureteral stones treatment using a real times ultrasound (US) focusing and to show how the Computerized Tomography (CT) scan parameters may be related to the outcomes. METHODS: We performed 70 consecutive supine transgluteal SWL of distal ureteral stones. All patients had a pre-treatment CT scan...
October 21, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
Takumi Takeuchi, Mami Hattori-Kato, Yumiko Okuno, Atsushi Kanatani, Masayoshi Zaitsu, Koji Mikami
Various conditions including distal renal tubular acidosis (dRTA) can induce stone formation in the kidney. dRTA is characterized by an impairment of urine acidification in the distal nephron. dRTA is caused by variations in genes functioning in intercalated cells including SLC4A1/AE1/Band3 transcribing two kinds of mRNAs encoding the Cl(-)/HCO3(-) exchanger in erythrocytes and that expressed in α-intercalated cells (kAE1). With the acid-loading test, 25% of urolithiasis patients were diagnosed with incomplete dRTA...
October 21, 2016: Scientific Reports
David I Chu, Gregory E Tasian, Lawrence Copelovitch
Pediatric stone disease is increasing in incidence and healthcare costs. With more years at-risk for stone recurrence during their lifetimes, children with nephrolithiasis constitute a high-risk patient population that requires focused intervention through both medical and surgical means. Through high-quality future studies to compare methods of stone prevention and treatment, the burden of stone disease on the youngest members of society may be ameliorated.
June 2016: Current Treatment Options in Pediatrics
Matthew C Ferroni, Kevin J Rycyna, Timothy D Averch, Michelle J Semins
PURPOSE: Vitamin D deficiency is often detected during metabolic evaluation in the nephrolithiasis population. Multiple vitamin D repletion protocols exist, however their differing impact on urinary stone formation risk factors is unclear. MATERIALS AND METHODS: Patients with a history of calcium stones and vitamin D deficiency (<30ng/ml) were randomized to receive either 1,000 International Units (IU) daily or 50,000 IU weekly of vitamin D supplementation for 6 weeks...
October 17, 2016: Journal of Urology
Chi-Fai Ng, Sylvia Luke, Chi-Hang Yee, Winnie Chu, Ka-Tak Wong, John Yuen
Objectives To perform a prospective study to evaluate the renal protective effects of ramping protocol and pause protocol for extracorporeal shockwave lithotripsy in human subjects. Patients and Methods 320 patients with solitary renal stone <15mm, were randomized to receive one of four protocols: (1) 80% power from beginning until the end of treatment; (2) the first 100 SWs at 40% power, and then 80% power until the end of treatment; (3) the first 100 shocks at 40% power, followed by a 3-minute pause and then further SWs at 80% power until the end of treatment; and (4) the first 100 shocks at 80% power, followed by a 3-minute pause and then further SWs at 80% power until the end of treatment...
October 20, 2016: Journal of Endourology
Shih-Yi Lin, Cheng-Li Lin, Chao-Hsiang Chang, His-Chin Wu, Wen-Chi Chen, I-Kuan Wang, Yao Lung Liu, Fung-Chang Sung, Yen-Jung Chang, Chia-Hung Kao
Large cohort studies on whether any association existed between urological interventions for urolithiasis and the development of CKD are lacking. From claims data of the National Health Insurance (NHI) program of Taiwan, we identified 54,433 patients newly diagnosed with urolithiasis during 1998-2010. For each case, four individuals without urolithiasis were randomly selected and frequency matched by age, sex, and diagnosis year. Both groups were followed up until the end of 2010. Incident CKD events were identified by the International Classification of Diseases, Ninth Revision (ICD-9) code in the NHI registration database...
October 19, 2016: Urolithiasis
Ben H Chew, Dirk Lange
Open ureterolithotomy and pyelolithotomy used to be first line therapy for treating kidney and ureteral stones. With the advent of shockwave lithotripsy, open stone surgery became less prevalent, but once ureteroscopy became more prevalent, open stone surgery became all but extinct. Advances in smaller, more flexible endoscopes and improvements in intracorporeal lithotripters, ureteroscopy has become a mainstay of therapy for kidney stones. The holmium:YAG laser can be utilized through flexible instruments and fragments any stone no matter what it is composed of...
October 19, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
Helena Chang, David T Tzou, Manint Usawachintachit, Brian D Duty, Ryan S Hsi, Jonathan D Harper, Mathew D Sorensen, Marshall Stoller, Roger L Sur, Thomas Chi
<b>Objectives</b>: Registry-based clinical research in nephrolithiasis is critical to advancing quality in urinary stone disease management and ultimately reducing stone recurrence. A need exists to develop HIPAA-compliant registries comprised of integrated electronic health record (EHR) data using prospectively defined variables. An EHR-based standardized patient database - The Registry for Stones of the Kidney & Ureter (ReSKU™) was developed and herein we describe our implementation outcomes...
October 19, 2016: Journal of Endourology
Casey A Dauw, Michael Borofsky, Nadya York, James E Lingeman
INTRODUCTION: The holmium laser has revolutionized the practice of minimally invasive endoscopy for kidney stones. Recently, a novel, rigid hand-piece for use in percutaneous nephrolithotomy (PCNL) that couples the holmium laser with suction has been developed. To date, there exists limited data regarding the usability and ergonomics of such treatment systems. We thus sought to compare surgeon-rated usability with three different suction laser hand-pieces in a porcine model. METHODS: We performed bilateral reverse PCNL on 4 female domestic farm pigs...
October 19, 2016: Journal of Endourology
Jodi A Antonelli, Heather Beardsley, Stephen Faddegon, Monica Sc Morgan, Jeffrey C Gahan, Margaret S Pearle, Jeffrey A Cadeddu
PURPOSE: We developed a polyethylene sack (the PercSac) that fits over the shaft of a rigid nephroscope and is deployed into the collecting system to capture a stone and contain fragments during PCNL. We previously reported results using the PercSac in a percutaneous cystolithopaxy model. Herein we compare the efficiency of stone fragmentation with and without the PercSac in an anatomically correct in vitro PCNL model. MATERIALS AND METHODS: The PCNL model consisted of a human collecting system model created on a 3-D printer...
October 19, 2016: Journal of Endourology
Vahit Guzelburc, Mehmet Balasar, Mukaddes Colakogullari, Selcuk Guven, Abdulkadir Kandemir, Ahmet Ozturk, Pelin Karaaslan, Bulent Erkurt, Selami Albayrak
PURPOSE: Irrigation-induced increase in intrarenal pressure is of concern because it may cause infection due to increased pyelovenous and pyelolymphatic absorption. This study is the first to compare prospectively the absorbed fluid volumes during percutaneous nephrolithotomy (PCNL) and retrograde intrarenal surgery (RIRS) for stones larger than 2 cm. MATERIALS AND METHODS: General anesthesia was applied to all patients. Isotonic solution containing 1 % ethanol was used as irrigation fluid...
2016: SpringerPlus
Ravindra D Hiremath, Sunil S Jalalpure
OBJECTIVE: Aim of this study is to evaluate antiurolithiatic potential of whole plant hydro-alcoholic (30:70) extract of Vernonia cinerea Less. in accordance to its claims made in ancient literature and also being one of the ingredients of cystone, a marketed formulation widely used in the management of urolithiasis. MATERIALS AND METHODS: To induce urolithiasis, 0.75% v/v ethylene glycol was administered orally for 14 days. The curative dose of 400 mg/kg b.w. and preventive doses of 100, 200, and 400 mg/kg b...
July 2016: Indian Journal of Pharmacology
Abdussamet Batur
Primary hyperparathyroidism (pHPT) is a condition caused by excessive and uncontrolled secretion of parathyroid hormone. The classical presenting symptoms in primary hyperparathyroidism are renal stones, hypercalcemic crisis, soft tissue calcifications, and cystic bone disease. Although most cases of pHPT are detected early and before symptomatic lesions appear, some patients may present late in the course of their disease. In this report, we present a patient with extensive parenchymal calcifications forming a cast of the right kidney which is called as "putty kidney" with Brown tumor located in the pubic ramus...
September 2016: Saudi Journal of Kidney Diseases and Transplantation
Dean G Assimos
No abstract text is available yet for this article.
November 2016: Journal of Urology
Zhuo Liu, Hongyang Jiang, Jun Yang, Tao Wang, Yufeng Ding, Jihong Liu, Shaogang Wang, Zhangqun Ye
Calcium oxalate stones account for >80% of urinary stones, however the mechanisms underlying their formation remains to be elucidated. Hyperoxaluria serves an important role in the pathophysiological process of stone formation. In the present study, differences in the miRNA expression profiles between experimental hyperoxaluric rats and normal rats were analyzed, in order to identify target genes and signaling pathways involved in the pathogenesis of hyperoxaluria. Ethylene glycol and ammonium chloride was fed to male hyperoxaluric rats (EXP) and normal age‑matched male rats (CON)...
October 12, 2016: Molecular Medicine Reports
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