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hypothyroidism elderly

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https://www.readbyqxmd.com/read/27901180/ultrasonographic-assessment-of-thyroid-volume-in-oldest-old-individuals
#1
Glaucia Cruzes Duarte, Lara Miguel Quirino Araujo, Felix Magalhães, Clineu Mello Almada, Maysa Seabra Cendoroglo
Objective: The aim of this study was to describe the relationship between thyroid volume and age, gender, anthropometric characteristics, and echogenicity in oldest-old subjects in an iodine-sufficient area. Subjects and methods: The study included 81 independent elderly individuals aged ≥ 80 years (65 [80.2%] women). We determined these individuals' anthropometric characteristics, body mass index (BMI), and lean body mass, as well as thyroid volume and echogenicity by ultrasonography...
November 24, 2016: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27766119/study-of-optimal-replacement-of-thyroxine-in-the-elderly-sorted-results-from-the-feasibility-randomised-controlled-trial
#2
Salman Razvi, Lorna Ingoe, Vicky Ryan, Simon H S Pearce, Scott Wilkes
BACKGROUND: Hypothyroidism is a common condition, particularly in the older population. Thyroid hormone requirements change with age and serum TSH levels also alter, especially in older patients. However, in practice laboratory reference ranges for thyroid function are not age-specific and treatment in older patients aims to achieve a similar target thyroid function level as younger age groups. METHODS: A dual centre, single blind, randomised controlled trial was conducted to determine the feasibility of a future definitive RCT in hypothyroid individuals aged 80 years or older who were treated with levothyroxine...
2016: Thyroid Research
https://www.readbyqxmd.com/read/27734699/-thyroid-hormones-and-cardiovascular-system
#3
Zdeňka Límanová, Jan Jiskra
Cardiovascular system is essentially affected by thyroid hormones by way of their genomic and non-genomic effects. Untreated overt thyroid dysfunction is associated with higher cardiovascular risk. Although it has been studied more than 3 decades, in subclinical thyroid dysfunction the negative effect on cardiovascular system is much more controversial. Large meta-analyses within last 10 years have shown that subclinical hyperthyroidism is associated with higher cardiovascular risk than subclinical hypothyroidism...
2016: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/27708714/the-presence-of-two-rare-genomic-syndromes-1q21-deletion-and-xq28-duplication-segregating-independently-in-a-family-with-intellectual-disability
#4
Kyungsoo Ha, Yiping Shen, Tyler Graves, Cheol-Hee Kim, Hyung-Goo Kim
BACKGROUND: 1q21 microdeletion syndrome is a rare contiguous gene deletion disorder with de novo or autosomal dominant inheritance patterns and its phenotypic features include intellectual disability, distinctive facial dysmorphism, microcephaly, cardiac abnormalities, and cataracts. MECP2 duplication syndrome is an X-linked recessive neurodevelopmental disorder characterized by intellectual disability, global developmental delay, and other neurological complications including late-onset seizures...
2016: Molecular Cytogenetics
https://www.readbyqxmd.com/read/27695826/subclinical-hypothyroidism-in-elderly-individuals-overdiagnosis-and-overtreatment-a-teachable-moment
#5
Paola Portillo-Sanchez, Rene Rodriguez-Gutierrez, Juan P Brito
No abstract text is available yet for this article.
December 1, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27664492/low-thyroid-stimulating-hormone-levels-are-associated-with-low-bone-mineral-density-in-femoral-neck-in-elderly-women
#6
Bo Ding, Ying Zhang, Qian Li, Yun Hu, Xiao-Jun Tao, Bing-Li Liu, Jian-Hua Ma, Dong-Mei Li
BACKGROUND AND AIMS: To determine the relationship between thyroid stimulating hormone (TSH) and bone mineral density (BMD) in elderly women. METHODS: This is a retrospective cross-sectional population cohort study of women aged ≥65 years. All 1097 subjects had no overt thyroid dysfunction, 47 had subclinical hyperthyroidism and 100 had subclinical hypothyroidism. Overall, 167 had normal BMD, 594 had osteopenia and 336 had osteoporosis. RESULTS: The femoral neck (FN) BMD was lower in women with lower TSH, with a high prevalance of osteoporosis and osteopenia (p = 0...
May 2016: Archives of Medical Research
https://www.readbyqxmd.com/read/27613262/-myxoedema-madness-with-capgras-syndrome-and-catatonic-features-responsive-to-combination-olanzapine-and-levothyroxine
#7
Maksim A Shlykov, Swapnil Rath, Alison Badger, Gerald Scott Winder
We present the case of an elderly woman with hypothyroidism and no psychiatric history who presented with new onset of psychosis, paranoia, catatonic features and Capgras syndrome (CS). This case illustrates the spectrum of neuropsychiatric symptoms that may accompany hypothyroidism and the importance of considering thyroid dysfunction as a primary contributor to severe psychiatric symptoms, especially in previously stable patients. We demonstrate the effectiveness of combination levothyroxine and olanzapine, with its favourable cardiac profile, in the treatment of myxoedema madness...
September 9, 2016: BMJ Case Reports
https://www.readbyqxmd.com/read/27546873/prevalence-of-hyponatremia-in-hypothyroid-patients-during-radioactive-%C3%A2-%C3%A2-%C3%A2-i-ablation-for-differentiated-thyroid-cancer-single-institution-experience
#8
Juan Carlo P Dayrit, Elaine C Cunanan, Sjoberg A Kho
BACKGROUND: Hyponatremia developing in hypothyroid patients has been encountered in clinical practice; however, its prevalence has not been well established. METHODS: Thirty patients diagnosed with differentiated thyroid cancer, rendered hypothyroid after surgery and levothyroxine withdrawal, and who are for radioactive iodine (RAI) ablation were included. Serum sodium concentrations were measured twice, at the time of admission for RAI ablation, and before discharge after increased oral fluid intake...
September 2016: Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27512537/takotsubo-cardiomyopathy-associated-with-severe-hypothyroidism-in-an-elderly-female
#9
Jorge A Brenes-Salazar
Takotsubo cardiomyopathy, also known as stress cardiomyopathy, is a syndrome that affects predominantly postmenopausal women. Despite multiple described mechanisms, intense, neuroadrenergic myocardial stimulation appears to be the main trigger. Hyperthyroidism, but rarely hypothyroidism, has been described in association with Takotsubo cardiomyopathy. Herein, we present a case of stress cardiomyopathy in the setting of symptomatic hypothyroidism.
April 2016: Heart Views: the Official Journal of the Gulf Heart Association
https://www.readbyqxmd.com/read/27509338/-subclinical-hypothyroidism-laboratory-finding-or-disease
#10
Richard Voigtländer, Dagmar Führer
Subclinical hypothyroidism first of all is a laboratory finding, defined by elevated TSH and normal peripheral thyroxine concentrations. The first steps are to verify the condition and to clarify whether the patient has underlying thyroid disease or other comorbidities. Results of recent studies on subclinical hypothyroidism are reassuring. No consistent association has been demonstrated between mildly elevated TSH levels (5-10 mIU / l) and cardiovascular events, mortality, fracture risk or cognitive impairment...
August 2016: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/27478458/preservation-of-renal-function-by-thyroid-hormone-replacement-in-elderly-persons-with-subclinical-hypothyroidism
#11
Yu Lu, Hong Guo, Dongmei Liu, Zhen Zhao
INTRODUCTION: The treatment of subclinical hypothyroidism in elderly persons is controversial. Previous studies have shown that there are interactions between kidney and thyroid function, but data regarding interventions that target thyroid function in elderly patients are scarce. We aimed to investigate the impact of thyroid hormone therapy on the estimated glomerular filtration rate (eGFR) in elderly patients. MATERIAL AND METHODS: Ninety elderly patients aged ≥ 65 years with subclinical hypothyroidism were followed for 36 months in our case-control study...
August 1, 2016: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/27403442/screening-of-undiagnosed-hypothyroidism-in-elderly-persons-with-diabetes-according-to-age-specific-reference-intervals-for-serum-thyroid-stimulating-hormone-and-the-impact-of-antidiabetes-drugs
#12
Rosita Fontes, Patricia de Fatima Dos Santos Teixeira, Mario Vaisman
Background. Studies have suggested that hypothyroidism is more frequent in the elderly with diabetes mellitus. However, an adaptation of TSH levels to age should be considered in this assessment. Some antidiabetes drugs reportedly interfere with TSH levels. The objectives of this study were to evaluate the prevalence of undiagnosed hypothyroidism in patients with diabetes and the influence of antidiabetes drugs. Material and Methods. 1160 subjects, 60 years and older (751 with diabetes), were studied; results were compared according to diabetes treatment and with persons without diabetes...
2016: Journal of Diabetes Research
https://www.readbyqxmd.com/read/27396589/cognitive-function-and-the-ageing-process-the-peculiar-role-of-mild-thyroid-failure
#13
Giuseppe Pasqualetti, Nadia Caraccio, Umberto Dell Agnello, Fabio Monzani
Over the last decades an increasing body of evidences suggested a possible relationship between thyroid hormone (TH) and the ageing process, and several efforts have been made to determine the actual role of TH dynamic during human life. It is still unclear whether the serum level shift of Thyroid Stimulating Hormone toward higher value, observed during ageing, is a normal adaptive response associated with senescence or an actual mild thyroid dysfunction. A growing body of evidence supports the hypothesis of a reset of the hypothalamus-pituitary-thyroid axis in order to contrast the catabolic status of the ageing process...
July 1, 2016: Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
https://www.readbyqxmd.com/read/27393881/hypothyroid-symptoms-fail-to-predict-thyroid-insufficiency-in-old-people-a-population-based-case-control-study
#14
Allan Carlé, Inge Bülow Pedersen, Nils Knudsen, Hans Perrild, Lars Ovesen, Stig Andersen, Peter Laurberg
BACKGROUND: Clinic-based studies have indicated that older hypothyroid patients may present only few symptoms. METHODS: In this population-based study of hypothyroidism, we investigated how the power of symptom presence predicts overt hypothyroidism in both young and older subjects. We identified patients newly diagnosed with overt autoimmune hypothyroidism in a population (n = 140, median thyroid-stimulating hormone, 54.5; 95% confidence interval [CI], 28.3-94...
October 2016: American Journal of Medicine
https://www.readbyqxmd.com/read/27335601/hypercalcemia-as-a-cause-of-kidney-failure-case-report
#15
Olivera Stojceva-Taneva, Borjanka Taneva, Gjulsen Selim
BACKGROUND: Hypercalcemia is a common manifestation in clinical practice and occurs as a result of primary hyperparathyroidism, malignancy, milk-alkali syndrome, hyper or hypothyroidism, sarcoidosis and other known and unknown causes. Patients with milk-alkali syndrome typically are presented with renal failure, hypercalcemia, and metabolic alkalosis caused by the ingestion of calcium and absorbable alkali. This syndrome is caused by high intake of milk and sodium bicarbonate. CASE PRESENTATION: We present a 28-year old male admitted to hospital with a one-month history of nausea, vomiting, epigastric pain, increased blood pressure and worsening of renal function with hypercalcemia...
June 15, 2016: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/27321605/abnormal-thyroid-stimulating-hormone-and-chronic-kidney-disease-in-elderly-adults-in-taipei-city
#16
Mei-Hsing Chuang, Kuo-Meng Liao, Yao-Min Hung, Paul Yung-Pou Wang, Yi-Chang Chou, Pesus Chou
OBJECTIVES: To examine whether older people with abnormal thyroid function are more likely to develop chronic kidney disease (CKD) over a 5-year follow-up period. DESIGN: Retrospective cohort study. SETTING: Health examination data from the Taipei Databank for Public Health Analysis. PARTICIPANTS: Individuals aged 65 and older (N = 41,454). MEASUREMENTS: Thyroid-stimulating hormone (TSH) levels were repeatedly measured, and subjects were categorized into four thyroid function groups (hyperthyroid, euthyroid, subclinical hypothyroid, overt hypothyroid)...
June 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27277348/estimation-of-thyroid-hormone-in-early-pregnancy-and-it-s-clinical-correlation
#17
M K Jahan, K Nahar, M Islam, M Shafiquzzaman, S Nahar, S Easmin, M Mohsin, S K Sarkar, M A Hossain
This descriptive cross sectional study was done for the estimation of thyroid hormone in early pregnancy and it's clinical correlation. It was conducted at the Antenatal Clinic of Mymensingh Medical College Hospital, Mymensingh from December 2010 to November 2011. Total 185 cases in early pregnancy were taken purposively and randomly. Among the pregnant women, age ranged from 18-42 years with the Mean±SD age 25.77±4.96 years, the gestational weeks ranged 6±1 to 13±1weeks having Mean±SD 9.06± 2.49 weeks...
April 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27271351/poor-glycemic-control-is-associated-with-the-risk-of-subclinical-hypothyroidism-in-patients-with-type-2-diabetes-mellitus
#18
Jae Ho Cho, Ho Jin Kim, Jun Ho Lee, Il Rae Park, Jun Sung Moon, Ji Sung Yoon, In-Kyu Lee, Kyu Chang Won, Hyoung Woo Lee
BACKGROUND/AIMS: Overt hypothyroidism is frequently found in patients with type 2 diabetes mellitus (T2DM), but it remains unknown the relationship between subclinical hypothyroidism (SCH) and T2DM. We attempt to evaluate the difference in prevalence of SCH between patients with T2DM and general population, and the association between SCH and glycemic control status ofdiabetic patients. METHODS: This was cross-sectional study. Total 8,528 subjects who visited for health check-up were recruited...
July 2016: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/27255129/the-thyroid-disease-in-the-elderly-our-experience
#19
Matteo Angelo Cannizzaro, Antonino Buffone, Salvatore Lo Bianco, Valeriya Okatyeva, Dario Cavallaro, Valerio Caruso, Pietro Caglià
INTRODUCTION: The number of elderly people in Italy is growing, so it is important to study the presentation of diseases in these subjects. MATERIALS AND METHODS: We selected 1362 patients who underwent thyroidectomy for different thyroid diseases from January 2008 to December 2014. The patients weredivided into two groups, according to the age. The patients aged 65 years and over were included in the group A, and the patients under the age of 65 years were included in the group B...
September 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27176656/asymptomatic-urinary-retention-in-elderly-women-upon-admission-to-the-internal-medicine-department-a-prospective-study
#20
Dan Justo, Natalia Schwartz, Eliyahu Dvorkin, Irina Gringauz, Asnat Groutz
AIM: To assess the incidence and associated risk factors of asymptomatic urinary retention in elderly women upon admission to the Internal Medicine department. METHODS: Two hundred and two consecutive elderly women (mean age 84.4 ± 5.7 years) who were admitted to four Internal Medicine departments at a tertiary medical center were prospectively enrolled. All patients underwent post-void residual urine (PVR) measurements on the morning following the admission day...
May 13, 2016: Neurourology and Urodynamics
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