Amélie Rollé, Elsa Vidal, Pierre Laguette, Yohann Garnier, Delphine Delta, Frédéric Martino, Patrick Portecop, Maryse Etienne-Julan, Pascale Piednoir, Audrey De Jong, Marc Romana, Emmanuelle Bernit
Background and Objectives : Pain management poses a significant challenge for patients experiencing vaso-occlusive crisis (VOC) in sickle cell disease (SCD). While opioid therapy is highly effective, its efficacy can be impeded by undesirable side effects. Local regional anesthesia (LRA), involving the deposition of a perineural anesthetic, provides a nociceptive blockade, local vasodilation and reduces the inflammatory response. However, the effectiveness of this therapeutic approach for VOC in SCD patients has been rarely reported up to now...
December 18, 2023: Medicina