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Scott Roy

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https://www.readbyqxmd.com/read/28190732/the-macronuclear-genome-of-stentor-coeruleus-reveals-tiny-introns-in-a-giant-cell
#1
Mark M Slabodnick, J Graham Ruby, Sarah B Reiff, Estienne C Swart, Sager Gosai, Sudhakaran Prabakaran, Ewa Witkowska, Graham E Larue, Susan Fisher, Robert M Freeman, Jeremy Gunawardena, William Chu, Naomi A Stover, Brian D Gregory, Mariusz Nowacki, Joseph Derisi, Scott W Roy, Wallace F Marshall, Pranidhi Sood
The giant, single-celled organism Stentor coeruleus has a long history as a model system for studying pattern formation and regeneration in single cells. Stentor [1, 2] is a heterotrichous ciliate distantly related to familiar ciliate models, such as Tetrahymena or Paramecium. The primary distinguishing feature of Stentor is its incredible size: a single cell is 1 mm long. Early developmental biologists, including T.H. Morgan [3], were attracted to the system because of its regenerative abilities-if large portions of a cell are surgically removed, the remnant reorganizes into a normal-looking but smaller cell with correct proportionality [2, 3]...
February 8, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28148611/reducing-acute-kidney-injury-due-to-contrast-material-how-nurses-can-improve-patient-safety
#2
Peggy Lambert, Kristine Chaisson, Susan Horton, Carmen Petrin, Emily Marshall, Sue Bowden, Lynn Scott, Sheila Conley, Janette Stender, Gertrude Kent, Ellen Hopkins, Brian Smith, Anita Nicholson, Nancy Roy, Brenda Homsted, Cindy Downs, Cathy S Ross, Jeremiah Brown
BACKGROUND: Acute kidney injury due to contrast material occurs in 3% to 15% of the 2 million cardiac catheterizations done in the United States each year. OBJECTIVE: To reduce acute kidney injury due to contrast material after cardiovascular interventional procedures. METHODS: Nurse leaders in the Northern New England Cardiovascular Disease Study Group, a 10-center quality improvement consortium in Maine, New Hampshire, and Vermont, formed a nursing task force to reduce acute kidney injury due to contrast material after cardiovascular interventional procedures...
February 2017: Critical Care Nurse
https://www.readbyqxmd.com/read/28140672/head-injury-serum-markers-for-assessing-response-to-trauma-design-of-the-headsmart-study
#3
Matthew E Peters, Vani Rao, Kathleen T Bechtold, Durga Roy, Haris I Sair, Jeannie-Marie Leoutsakos, Ramon Diaz-Arrastia, Robert D Stevens, D Scott Batty, Hayley Falk, Christopher Fernandez, Uju Ofoche, Alexandra Vassila, Anna J Hall, Braden Anderson, Edward Bessman, Constantine G Lyketsos, Allen D Everett, Jennifer Van Eyk, Frederick K Korley
BACKGROUND: Accurate diagnosis and risk stratification of traumatic brain injury (TBI) at time of presentation remains a clinical challenge. The Head Injury Serum Markers for Assessing Response to Trauma study (HeadSMART) aims to examine blood-based biomarkers for diagnosing and determining prognosis in TBI. METHODS: HeadSMART is a 6-month prospective cohort study comparing emergency department patients evaluated for TBI (exposure group) to (1) emergency department patients evaluated for traumatic injury without head trauma and (2) healthy persons...
January 31, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28134564/glucose-outcomes-with-the-in-home-use-of-a-hybrid-closed-loop-insulin-delivery-system-in-adolescents-and-adults-with-type-1-diabetes
#4
Satish K Garg, Stuart A Weinzimer, William V Tamborlane, Bruce A Buckingham, Bruce W Bode, Timothy S Bailey, Ronald L Brazg, Jacob Ilany, Robert H Slover, Stacey M Anderson, Richard M Bergenstal, Benyamin Grosman, Anirban Roy, Toni L Cordero, John Shin, Scott W Lee, Francine R Kaufman
BACKGROUND: The safety and effectiveness of the in-home use of a hybrid closed-loop (HCL) system that automatically increases, decreases, and suspends insulin delivery in response to continuous glucose monitoring were investigated. METHODS: Adolescents (n = 30, ages 14-21 years) and adults (n = 94, ages 22-75 years) with type 1 diabetes participated in a multicenter (nine sites in the United States, one site in Israel) pivotal trial. The Medtronic MiniMed(®) 670G system was used during a 2-week run-in phase without HCL control, or Auto Mode, enabled (Manual Mode) and, thereafter, with Auto Mode enabled during a 3-month study phase...
January 30, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28109339/stigma-reduction-training-improves-healthcare-provider-attitudes-toward-and-experiences-of-young-marginalized-people-in-bangladesh
#5
Scott Geibel, Sharif M I Hossain, Julie Pulerwitz, Nargis Sultana, Tarik Hossain, Shongkour Roy, Brady Burnett-Zieman, Lucy Stackpool-Moore, Barbara A Friedland, Reena Yasmin, Najmus Sadiq, Eileen Yam
PURPOSE: Working with health providers to reduce HIV stigma in the healthcare setting is an important strategy to improve service utilization and quality of care, especially for young people who are sexually active before marriage, are sexual minorities, or who sell sex. A stigma reduction training program for health providers in Bangladesh was evaluated. METHODS: A cohort of 300 healthcare providers were given a self-administered questionnaire, then attended a 2-day HIV and sexual and reproductive health and rights training (including a 90-minute session on stigma issues)...
February 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28090405/transcriptomic-analysis-of-diplomonad-parasites-reveals-a-trans-spliced-intron-in-a-helicase-gene-in-giardia
#6
Scott William Roy
BACKGROUND: The mechanisms by which DNA sequences are expressed is the central preoccupation of molecular genetics. Recently, ourselves and others reported that in the diplomonad protist Giardia lamblia, the coding regions of several mRNAs are produced by ligation of independent RNA species expressed from distinct genomic loci. Such trans-splicing of introns was found to affect nearly as many genes in this organism as does classical cis-splicing of introns. These findings raised questions about the incidence of intron trans-splicing both across the G...
2017: PeerJ
https://www.readbyqxmd.com/read/28080917/results-of-the-megaverebrate-analgesia-survey-giraffe-and-hippopotamus
#7
Matthew Boothe, Jack Kottwitz, Roy Harmon, Scott B Citino, Jeffery R Zuba, Dawn M Boothe
Results of an online survey posted on the American Association of Zoo Veterinarians listserv examined the patterns of analgesic medication and pain management modalities used for captive giraffe and hippopotami. Compiled data included signalment, drugs administered, dosing regimens, subjective efficacy scores, ease of administration, and adverse events. Nineteen institutions exhibiting hippopotami ( Hippopotamus amphibious ) and pygmy hippopotami (Choeropsis liberiensis) and 45 exhibiting giraffe ( Giraffa camelopardalis spp...
December 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28062539/tissue-expander-as-a-routine-component-of-50cc-total-artificial-heart-implantation-for-bridge-to-transplant
#8
Ryan Avery, Samata R Paidy, Roy Keller, Scott Lick, Richard G Smith, Zain Khalpey
No abstract text is available yet for this article.
January 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/28049566/an-analysis-of-two-genome-wide-association-meta-analyses-identifies-a-new-locus-for-broad-depression-phenotype
#9
Nese Direk, Stephanie Williams, Jennifer A Smith, Stephan Ripke, Tracy Air, Azmeraw T Amare, Najaf Amin, Bernhard T Baune, David A Bennett, Douglas H R Blackwood, Dorret Boomsma, Gerome Breen, Henriette N Buttenschøn, Enda M Byrne, Anders D Børglum, Enrique Castelao, Sven Cichon, Toni-Kim Clarke, Marilyn C Cornelis, Udo Dannlowski, Philip L De Jager, Ayse Demirkan, Enrico Domenici, Cornelia M van Duijn, Erin C Dunn, Johan G Eriksson, Tonu Esko, Jessica D Faul, Luigi Ferrucci, Myriam Fornage, Eco de Geus, Michael Gill, Scott D Gordon, Hans Jörgen Grabe, Gerard van Grootheest, Steven P Hamilton, Catharina A Hartman, Andrew C Heath, Karin Hek, Albert Hofman, Georg Homuth, Carsten Horn, Jouke Jan Hottenga, Sharon L R Kardia, Stefan Kloiber, Karestan Koenen, Zoltán Kutalik, Karl-Heinz Ladwig, Jari Lahti, Douglas F Levinson, Cathryn M Lewis, Glyn Lewis, Qingqin S Li, David J Llewellyn, Susanne Lucae, Kathryn L Lunetta, Donald J MacIntyre, Pamela Madden, Nicholas G Martin, Andrew M McIntosh, Andres Metspalu, Yuri Milaneschi, Grant W Montgomery, Ole Mors, Thomas H Mosley, Joanne M Murabito, Bertram Müller-Myhsok, Markus M Nöthen, Dale R Nyholt, Michael C O'Donovan, Brenda W Penninx, Michele L Pergadia, Roy Perlis, James B Potash, Martin Preisig, Shaun M Purcell, Jorge A Quiroz, Katri Räikkönen, John P Rice, Marcella Rietschel, Margarita Rivera, Thomas G Schulze, Jianxin Shi, Stanley Shyn, Grant C Sinnamon, Johannes H Smit, Jordan W Smoller, Harold Snieder, Toshiko Tanaka, Katherine E Tansey, Alexander Teumer, Rudolf Uher, Daniel Umbricht, Sandra Van der Auwera, Erin B Ware, David R Weir, Myrna M Weissman, Gonneke Willemsen, Jingyun Yang, Wei Zhao, Henning Tiemeier, Patrick F Sullivan
BACKGROUND: The genetics of depression has been explored in genome-wide association studies that focused on either major depressive disorder or depressive symptoms with mostly negative findings. A broad depression phenotype including both phenotypes has not been tested previously using a genome-wide association approach. We aimed to identify genetic polymorphisms significantly associated with a broad phenotype from depressive symptoms to major depressive disorder. METHODS: We analyzed two prior studies of 70,017 participants of European ancestry from general and clinical populations in the discovery stage...
December 8, 2016: Biological Psychiatry
https://www.readbyqxmd.com/read/27969529/ps01-62-long-term-safety-and-clinical-activity%C3%A2-of-atezolizumab-monotherapy%C3%A2-in-metastatic-nsclc-final%C3%A2-results-from-a-phase-ia-study-topic-medical-oncology
#10
Michael S Gordon, Roy S Herbst, Leora Horn, Jean-Charles Soria, Leena Gandhi, Enriqueta Felip, Lecia Sequist, David R Spigel, Scott J Antonia, Ani Balmanoukian, Philippe Cassier, Bo Liu, Marcin Kowanetz, Carol O'Hear, Marcella Fassò, Alan Sandler, Scott N Gettinger
No abstract text is available yet for this article.
November 2016: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/27929583/non-adiabatic-reactions-general-discussion
#11
Stuart C Althorpe, Nandini Ananth, Gonzalo Angulo, Raymond Dean Astumian, Vijay Beniwal, Jochen Blumberger, Peter G Bolhuis, Bernd Ensing, David R Glowacki, Scott Habershon, Sharon Hammes-Schiffer, Timothy J H Hele, Nancy Makri, David E Manolopoulos, Laura K McKemmish, Thomas F Miller Iii, William H Miller, Adrian J Mulholland, Tatiana Nekipelova, Eli Pollak, Jeremy O Richardson, Martin Richter, Priyadarshi Roy Chowdhury, Dmitry Shalashilin, Rafał Szabla
No abstract text is available yet for this article.
December 8, 2016: Faraday Discussions
https://www.readbyqxmd.com/read/27928723/boosting-weakened-synapses-to-treat-alzheimer-s-disease
#12
Robert J McDonald, Scott H Deibel
This paper highlights a recent report by Roy and colleagues showing that boosting plasticity in synapses activated during initial memory encoding ameliorates memory impairments found in the early stages of the familial version of Alzheimer's disease. Our goal was to describe the main features of the report and evaluate the approach and implications of the work.
December 7, 2016: Learning & Behavior
https://www.readbyqxmd.com/read/27919334/ionizing-radiation-induced-cataracts-recent-biological-and-mechanistic-developments-and-perspectives-for-future-research
#13
Elizabeth A Ainsbury, Stephen Barnard, Scott Bright, Claudia Dalke, Miguel Jarrin, Sarah Kunze, Rick Tanner, Joseph R Dynlacht, Roy A Quinlan, Jochen Graw, Munira Kadhim, Nobuyuki Hamada
The lens of the eye has long been considered as a radiosensitive tissue, but recent research has suggested that the radiosensitivity is even greater than previously thought. The 2012 recommendation of the International Commission on Radiological Protection (ICRP) to substantially reduce the annual occupational equivalent dose limit for the ocular lens has now been adopted in the European Union and is under consideration around the rest of the world. However, ICRP clearly states that the recommendations are chiefly based on epidemiological evidence because there are a very small number of studies that provide explicit biological, mechanistic evidence at doses <2Gy...
October 2016: Mutation Research
https://www.readbyqxmd.com/read/27898078/corrigendum-genetic-variants-associated-with-subjective-well-being-depressive-symptoms-and-neuroticism-identified-through-genome-wide-analyses
#14
Aysu Okbay, Bart M L Baselmans, Jan-Emmanuel De Neve, Patrick Turley, Michel G Nivard, Mark Alan Fontana, S Fleur W Meddens, Richard Karlsson Linnér, Cornelius A Rietveld, Jaime Derringer, Jacob Gratten, James J Lee, Jimmy Z Liu, Ronald de Vlaming, Tarunveer S Ahluwalia, Jadwiga Buchwald, Alana Cavadino, Alexis C Frazier-Wood, Nicholas A Furlotte, Victoria Garfield, Marie Henrike Geisel, Juan R Gonzalez, Saskia Haitjema, Robert Karlsson, Sander W van der Laan, Karl-Heinz Ladwig, Jari Lahti, Sven J van der Lee, Penelope A Lind, Tian Liu, Lindsay Matteson, Evelin Mihailov, Michael B Miller, Camelia C Minica, Ilja M Nolte, Dennis Mook-Kanamori, Peter J van der Most, Christopher Oldmeadow, Yong Qian, Olli Raitakari, Rajesh Rawal, Anu Realo, Rico Rueedi, Börge Schmidt, Albert V Smith, Evie Stergiakouli, Toshiko Tanaka, Kent Taylor, Gudmar Thorleifsson, Juho Wedenoja, Juergen Wellmann, Harm-Jan Westra, Sara M Willems, Wei Zhao, Najaf Amin, Andrew Bakshi, Sven Bergmann, Gyda Bjornsdottir, Patricia A Boyle, Samantha Cherney, Simon R Cox, Gail Davies, Oliver S P Davis, Jun Ding, Nese Direk, Peter Eibich, Rebecca T Emeny, Ghazaleh Fatemifar, Jessica D Faul, Luigi Ferrucci, Andreas J Forstner, Christian Gieger, Richa Gupta, Tamara B Harris, Juliette M Harris, Elizabeth G Holliday, Jouke-Jan Hottenga, Philip L De Jager, Marika A Kaakinen, Eero Kajantie, Ville Karhunen, Ivana Kolcic, Meena Kumari, Lenore J Launer, Lude Franke, Ruifang Li-Gao, David C Liewald, Marisa Koini, Anu Loukola, Pedro Marques-Vidal, Grant W Montgomery, Miriam A Mosing, Lavinia Paternoster, Alison Pattie, Katja E Petrovic, Laura Pulkki-Råback, Lydia Quaye, Katri Räikkönen, Igor Rudan, Rodney J Scott, Jennifer A Smith, Angelina R Sutin, Maciej Trzaskowski, Anna E Vinkhuyzen, Lei Yu, Delilah Zabaneh, John R Attia, David A Bennett, Klaus Berger, Lars Bertram, Dorret I Boomsma, Harold Snieder, Shun-Chiao Chang, Francesco Cucca, Ian J Deary, Cornelia M van Duijn, Johan G Eriksson, Ute Bültmann, Eco J C de Geus, Patrick J F Groenen, Vilmundur Gudnason, Torben Hansen, Catharine A Hartman, Claire M A Haworth, Caroline Hayward, Andrew C Heath, David A Hinds, Elina Hyppönen, William G William, Marjo-Riitta Järvelin, Karl-Heinz Jöckel, Jaakko Kaprio, Sharon L R Kardia, Liisa Keltikangas-Järvinen, Peter Kraft, Laura D Kubzansky, Terho Lehtimäki, Patrik K E Magnusson, Nicholas G Martin, Matt McGue, Andres Metspalu, Melinda Mills, Renée de Mutsert, Albertine J Oldehinkel, Gerard Pasterkamp, Nancy L Pedersen, Robert Plomin, Ozren Polasek, Christine Power, Stephen S Rich, Frits R Rosendaal, Hester M den Ruijter, David Schlessinger, Helena Schmidt, Rauli Svento, Reinhold Schmidt, Behrooz Z Alizadeh, Thorkild I A Sørensen, Tim D Spector, John M Starr, Kari Stefansson, Andrew Steptoe, Antonio Terracciano, Unnur Thorsteinsdottir, A Roy Thurik, Nicholas J Timpson, Henning Tiemeier, André G Uitterlinden, Peter Vollenweider, Gert G Wagner, David R Weir, Jian Yang, Dalton C Conley, George Davey Smith, Albert Hofman, Magnus Johannesson, David I Laibson, Sarah E Medland, Michelle N Meyer, Joseph K Pickrell, Tõnu Esko, Robert F Krueger, Jonathan P Beauchamp, Philipp D Koellinger, Daniel J Benjamin, Meike Bartels, David Cesarini
No abstract text is available yet for this article.
November 29, 2016: Nature Genetics
https://www.readbyqxmd.com/read/27835023/correlated-event-by-event-fluctuations-of-flow-harmonics-in-pb-pb-collisions-at-sqrt-s_-nn-2-76%C3%A2-%C3%A2-tev
#15
J Adam, D Adamová, M M Aggarwal, G Aglieri Rinella, M Agnello, N Agrawal, Z Ahammed, S Ahmad, S U Ahn, S Aiola, A Akindinov, S N Alam, D S D Albuquerque, D Aleksandrov, B Alessandro, D Alexandre, R Alfaro Molina, A Alici, A Alkin, J R M Almaraz, J Alme, T Alt, S Altinpinar, I Altsybeev, C Alves Garcia Prado, C Andrei, A Andronic, V Anguelov, T Antičić, F Antinori, P Antonioli, L Aphecetche, H Appelshäuser, S Arcelli, R Arnaldi, O W Arnold, I C Arsene, M Arslandok, B Audurier, A Augustinus, R Averbeck, M D Azmi, A Badalà, Y W Baek, S Bagnasco, R Bailhache, R Bala, S Balasubramanian, A Baldisseri, R C Baral, A M Barbano, R Barbera, F Barile, G G Barnaföldi, L S Barnby, V Barret, P Bartalini, K Barth, J Bartke, E Bartsch, M Basile, N Bastid, S Basu, B Bathen, G Batigne, A Batista Camejo, B Batyunya, P C Batzing, I G Bearden, H Beck, C Bedda, N K Behera, I Belikov, F Bellini, H Bello Martinez, R Bellwied, R Belmont, E Belmont-Moreno, L G E Beltran, V Belyaev, G Bencedi, S Beole, I Berceanu, A Bercuci, Y Berdnikov, D Berenyi, R A Bertens, D Berzano, L Betev, A Bhasin, I R Bhat, A K Bhati, B Bhattacharjee, J Bhom, L Bianchi, N Bianchi, C Bianchin, J Bielčík, J Bielčíková, A Bilandzic, G Biro, R Biswas, S Biswas, S Bjelogrlic, J T Blair, D Blau, C Blume, F Bock, A Bogdanov, H Bøggild, L Boldizsár, M Bombara, J Book, H Borel, A Borissov, M Borri, F Bossú, E Botta, C Bourjau, P Braun-Munzinger, M Bregant, T Breitner, T A Broker, T A Browning, M Broz, E J Brucken, E Bruna, G E Bruno, D Budnikov, H Buesching, S Bufalino, P Buncic, O Busch, Z Buthelezi, J B Butt, J T Buxton, J Cabala, D Caffarri, X Cai, H Caines, L Calero Diaz, A Caliva, E Calvo Villar, P Camerini, F Carena, W Carena, F Carnesecchi, J Castillo Castellanos, A J Castro, E A R Casula, C Ceballos Sanchez, J Cepila, P Cerello, J Cerkala, B Chang, S Chapeland, M Chartier, J L Charvet, S Chattopadhyay, S Chattopadhyay, A Chauvin, V Chelnokov, M Cherney, C Cheshkov, B Cheynis, V Chibante Barroso, D D Chinellato, S Cho, P Chochula, K Choi, M Chojnacki, S Choudhury, P Christakoglou, C H Christensen, P Christiansen, T Chujo, S U Chung, C Cicalo, L Cifarelli, F Cindolo, J Cleymans, F Colamaria, D Colella, A Collu, M Colocci, G Conesa Balbastre, Z Conesa Del Valle, M E Connors, J G Contreras, T M Cormier, Y Corrales Morales, I Cortés Maldonado, P Cortese, M R Cosentino, F Costa, P Crochet, R Cruz Albino, E Cuautle, L Cunqueiro, T Dahms, A Dainese, M C Danisch, A Danu, D Das, I Das, S Das, A Dash, S Dash, S De, A De Caro, G de Cataldo, C de Conti, J de Cuveland, A De Falco, D De Gruttola, N De Marco, S De Pasquale, R D De Souza, A Deisting, A Deloff, E Dénes, C Deplano, P Dhankher, D Di Bari, A Di Mauro, P Di Nezza, B Di Ruzza, M A Diaz Corchero, T Dietel, P Dillenseger, R Divià, Ø Djuvsland, A Dobrin, D Domenicis Gimenez, B Dönigus, O Dordic, T Drozhzhova, A K Dubey, A Dubla, L Ducroux, P Dupieux, R J Ehlers, D Elia, E Endress, H Engel, E Epple, B Erazmus, I Erdemir, F Erhardt, B Espagnon, M Estienne, S Esumi, J Eum, D Evans, S Evdokimov, G Eyyubova, L Fabbietti, D Fabris, J Faivre, A Fantoni, M Fasel, L Feldkamp, A Feliciello, G Feofilov, J Ferencei, A Fernández Téllez, E G Ferreiro, A Ferretti, A Festanti, V J G Feuillard, J Figiel, M A S Figueredo, S Filchagin, D Finogeev, F M Fionda, E M Fiore, M G Fleck, M Floris, S Foertsch, P Foka, S Fokin, E Fragiacomo, A Francescon, A Francisco, U Frankenfeld, G G Fronze, U Fuchs, C Furget, A Furs, M Fusco Girard, J J Gaardhøje, M Gagliardi, A M Gago, K Gajdosova, M Gallio, C D Galvan, D R Gangadharan, P Ganoti, C Gao, C Garabatos, E Garcia-Solis, C Gargiulo, P Gasik, E F Gauger, M Germain, M Gheata, P Ghosh, S K Ghosh, P Gianotti, P Giubellino, P Giubilato, E Gladysz-Dziadus, P Glässel, D M Goméz Coral, A Gomez Ramirez, A S Gonzalez, V Gonzalez, P González-Zamora, S Gorbunov, L Görlich, S Gotovac, V Grabski, O A Grachov, L K Graczykowski, K L Graham, A Grelli, A Grigoras, C Grigoras, V Grigoriev, A Grigoryan, S Grigoryan, B Grinyov, N Grion, J M Gronefeld, J F Grosse-Oetringhaus, R Grosso, L Gruber, F Guber, R Guernane, B Guerzoni, K Gulbrandsen, T Gunji, A Gupta, R Gupta, R Haake, Ø Haaland, C Hadjidakis, M Haiduc, H Hamagaki, G Hamar, J C Hamon, J W Harris, A Harton, D Hatzifotiadou, S Hayashi, S T Heckel, E Hellbär, H Helstrup, A Herghelegiu, G Herrera Corral, B A Hess, K F Hetland, H Hillemanns, B Hippolyte, D Horak, R Hosokawa, P Hristov, C Hughes, T J Humanic, N Hussain, T Hussain, D Hutter, D S Hwang, R Ilkaev, M Inaba, E Incani, M Ippolitov, M Irfan, M Ivanov, V Ivanov, V Izucheev, B Jacak, N Jacazio, P M Jacobs, M B Jadhav, S Jadlovska, J Jadlovsky, C Jahnke, M J Jakubowska, H J Jang, M A Janik, P H S Y Jayarathna, C Jena, S Jena, R T Jimenez Bustamante, P G Jones, A Jusko, P Kalinak, A Kalweit, J Kamin, J H Kang, V Kaplin, S Kar, A Karasu Uysal, O Karavichev, T Karavicheva, L Karayan, E Karpechev, U Kebschull, R Keidel, D L D Keijdener, M Keil, M Mohisin Khan, P Khan, S A Khan, A Khanzadeev, Y Kharlov, B Kileng, D W Kim, D J Kim, D Kim, H Kim, J S Kim, J Kim, M Kim, S Kim, T Kim, S Kirsch, I Kisel, S Kiselev, A Kisiel, G Kiss, J L Klay, C Klein, J Klein, C Klein-Bösing, S Klewin, A Kluge, M L Knichel, A G Knospe, C Kobdaj, M Kofarago, T Kollegger, A Kolojvari, V Kondratiev, N Kondratyeva, E Kondratyuk, A Konevskikh, M Kopcik, M Kour, C Kouzinopoulos, O Kovalenko, V Kovalenko, M Kowalski, G Koyithatta Meethaleveedu, I Králik, A Kravčáková, M Krivda, F Krizek, E Kryshen, M Krzewicki, A M Kubera, V Kučera, C Kuhn, P G Kuijer, A Kumar, J Kumar, L Kumar, S Kumar, P Kurashvili, A Kurepin, A B Kurepin, A Kuryakin, M J Kweon, Y Kwon, S L La Pointe, P La Rocca, P Ladron de Guevara, C Lagana Fernandes, I Lakomov, R Langoy, K Lapidus, C Lara, A Lardeux, A Lattuca, E Laudi, R Lea, L Leardini, G R Lee, S Lee, F Lehas, S Lehner, R C Lemmon, V Lenti, E Leogrande, I León Monzón, H León Vargas, M Leoncino, P Lévai, S Li, X Li, J Lien, R Lietava, S Lindal, V Lindenstruth, C Lippmann, M A Lisa, H M Ljunggren, D F Lodato, P I Loenne, V Loginov, C Loizides, X Lopez, E López Torres, A Lowe, P Luettig, M Lunardon, G Luparello, T H Lutz, A Maevskaya, M Mager, S Mahajan, S M Mahmood, A Maire, R D Majka, M Malaev, I Maldonado Cervantes, L Malinina, D Mal'Kevich, P Malzacher, A Mamonov, V Manko, F Manso, V Manzari, M Marchisone, J Mareš, G V Margagliotti, A Margotti, J Margutti, A Marín, C Markert, M Marquard, N A Martin, J Martin Blanco, P Martinengo, M I Martínez, G Martínez García, M Martinez Pedreira, A Mas, S Masciocchi, M Masera, A Masoni, A Mastroserio, A Matyja, C Mayer, J Mazer, M A Mazzoni, D Mcdonald, F Meddi, Y Melikyan, A Menchaca-Rocha, E Meninno, J Mercado Pérez, M Meres, Y Miake, M M Mieskolainen, K Mikhaylov, L Milano, J Milosevic, A Mischke, A N Mishra, D Miśkowiec, J Mitra, C M Mitu, N Mohammadi, B Mohanty, L Molnar, L Montaño Zetina, E Montes, D A Moreira De Godoy, L A P Moreno, S Moretto, A Morreale, A Morsch, V Muccifora, E Mudnic, D Mühlheim, S Muhuri, M Mukherjee, J D Mulligan, M G Munhoz, K Münning, R H Munzer, H Murakami, S Murray, L Musa, J Musinsky, B Naik, R Nair, B K Nandi, R Nania, E Nappi, M U Naru, H Natal da Luz, C Nattrass, S R Navarro, K Nayak, R Nayak, T K Nayak, S Nazarenko, A Nedosekin, L Nellen, F Ng, M Nicassio, M Niculescu, J Niedziela, B S Nielsen, S Nikolaev, S Nikulin, V Nikulin, F Noferini, P Nomokonov, G Nooren, J C C Noris, J Norman, A Nyanin, J Nystrand, H Oeschler, S Oh, S K Oh, A Ohlson, A Okatan, T Okubo, J Oleniacz, A C Oliveira Da Silva, M H Oliver, J Onderwaater, C Oppedisano, R Orava, M Oravec, A Ortiz Velasquez, A Oskarsson, J Otwinowski, K Oyama, M Ozdemir, Y Pachmayer, D Pagano, P Pagano, G Paić, S K Pal, J Pan, A K Pandey, V Papikyan, G S Pappalardo, P Pareek, W J Park, S Parmar, A Passfeld, V Paticchio, R N Patra, B Paul, H Pei, T Peitzmann, X Peng, H Pereira Da Costa, D Peresunko, E Perez Lezama, V Peskov, Y Pestov, V Petráček, V Petrov, M Petrovici, C Petta, S Piano, M Pikna, P Pillot, L O D L Pimentel, O Pinazza, L Pinsky, D B Piyarathna, M Płoskoń, M Planinic, J Pluta, S Pochybova, P L M Podesta-Lerma, M G Poghosyan, B Polichtchouk, N Poljak, W Poonsawat, A Pop, H Poppenborg, S Porteboeuf-Houssais, J Porter, J Pospisil, S K Prasad, R Preghenella, F Prino, C A Pruneau, I Pshenichnov, M Puccio, G Puddu, P Pujahari, V Punin, J Putschke, H Qvigstad, A Rachevski, S Raha, S Rajput, J Rak, A Rakotozafindrabe, L Ramello, F Rami, R Raniwala, S Raniwala, S S Räsänen, B T Rascanu, D Rathee, K F Read, K Redlich, R J Reed, A Rehman, P Reichelt, F Reidt, X Ren, R Renfordt, A R Reolon, A Reshetin, K Reygers, V Riabov, R A Ricci, T Richert, M Richter, P Riedler, W Riegler, F Riggi, C Ristea, E Rocco, M Rodríguez Cahuantzi, A Rodriguez Manso, K Røed, E Rogochaya, D Rohr, D Röhrich, F Ronchetti, L Ronflette, P Rosnet, A Rossi, F Roukoutakis, A Roy, C Roy, P Roy, A J Rubio Montero, R Rui, R Russo, E Ryabinkin, Y Ryabov, A Rybicki, S Saarinen, S Sadhu, S Sadovsky, K Šafařík, B Sahlmuller, P Sahoo, R Sahoo, S Sahoo, P K Sahu, J Saini, S Sakai, M A Saleh, J Salzwedel, S Sambyal, V Samsonov, L Šándor, A Sandoval, M Sano, D Sarkar, N Sarkar, P Sarma, E Scapparone, F Scarlassara, C Schiaua, R Schicker, C Schmidt, H R Schmidt, M Schmidt, S Schuchmann, J Schukraft, M Schulc, Y Schutz, K Schwarz, K Schweda, G Scioli, E Scomparin, R Scott, M Šefčík, J E Seger, Y Sekiguchi, D Sekihata, I Selyuzhenkov, K Senosi, S Senyukov, E Serradilla, A Sevcenco, A Shabanov, A Shabetai, O Shadura, R Shahoyan, M I Shahzad, A Shangaraev, A Sharma, M Sharma, M Sharma, N Sharma, A I Sheikh, K Shigaki, Q Shou, K Shtejer, Y Sibiriak, S Siddhanta, K M Sielewicz, T Siemiarczuk, D Silvermyr, C Silvestre, G Simatovic, G Simonetti, R Singaraju, R Singh, V Singhal, T Sinha, B Sitar, M Sitta, T B Skaali, M Slupecki, N Smirnov, R J M Snellings, T W Snellman, J Song, M Song, Z Song, F Soramel, S Sorensen, F Sozzi, M Spacek, E Spiriti, I Sputowska, M Spyropoulou-Stassinaki, J Stachel, I Stan, P Stankus, E Stenlund, G Steyn, J H Stiller, D Stocco, P Strmen, A A P Suaide, T Sugitate, C Suire, M Suleymanov, M Suljic, R Sultanov, M Šumbera, S Sumowidagdo, A Szabo, I Szarka, A Szczepankiewicz, M Szymanski, U Tabassam, J Takahashi, G J Tambave, N Tanaka, M Tarhini, M Tariq, M G Tarzila, A Tauro, G Tejeda Muñoz, A Telesca, K Terasaki, C Terrevoli, B Teyssier, J Thäder, D Thakur, D Thomas, R Tieulent, A Tikhonov, A R Timmins, A Toia, S Trogolo, G Trombetta, V Trubnikov, W H Trzaska, T Tsuji, A Tumkin, R Turrisi, T S Tveter, K Ullaland, A Uras, G L Usai, A Utrobicic, M Vala, L Valencia Palomo, S Vallero, J Van Der Maarel, J W Van Hoorne, M van Leeuwen, T Vanat, P Vande Vyvre, D Varga, A Vargas, M Vargyas, R Varma, M Vasileiou, A Vasiliev, A Vauthier, O Vázquez Doce, V Vechernin, A M Veen, M Veldhoen, A Velure, E Vercellin, S Vergara Limón, R Vernet, M Verweij, L Vickovic, J Viinikainen, Z Vilakazi, O Villalobos Baillie, A Villatoro Tello, A Vinogradov, L Vinogradov, Y Vinogradov, T Virgili, V Vislavicius, Y P Viyogi, A Vodopyanov, M A Völkl, K Voloshin, S A Voloshin, G Volpe, B von Haller, I Vorobyev, D Vranic, J Vrláková, B Vulpescu, B Wagner, J Wagner, H Wang, M Wang, D Watanabe, Y Watanabe, M Weber, S G Weber, D F Weiser, J P Wessels, U Westerhoff, A M Whitehead, J Wiechula, J Wikne, G Wilk, J Wilkinson, M C S Williams, B Windelband, M Winn, P Yang, S Yano, Z Yasin, Z Yin, H Yokoyama, I-K Yoo, J H Yoon, V Yurchenko, A Zaborowska, V Zaccolo, A Zaman, C Zampolli, H J C Zanoli, S Zaporozhets, N Zardoshti, A Zarochentsev, P Závada, N Zaviyalov, H Zbroszczyk, I S Zgura, M Zhalov, H Zhang, X Zhang, Y Zhang, C Zhang, Z Zhang, C Zhao, N Zhigareva, D Zhou, Y Zhou, Z Zhou, H Zhu, J Zhu, A Zichichi, A Zimmermann, M B Zimmermann, G Zinovjev, M Zyzak
We report the measurements of correlations between event-by-event fluctuations of amplitudes of anisotropic flow harmonics in nucleus-nucleus collisions, obtained for the first time using a new analysis method based on multiparticle cumulants in mixed harmonics. This novel method is robust against systematic biases originating from nonflow effects and by construction any dependence on symmetry planes is eliminated. We demonstrate that correlations of flow harmonics exhibit a better sensitivity to medium properties than the individual flow harmonics...
October 28, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27832824/genome-of-the-asian-longhorned-beetle-anoplophora-glabripennis-a-globally-significant-invasive-species-reveals-key-functional-and-evolutionary-innovations-at-the-beetle-plant-interface
#16
Duane D McKenna, Erin D Scully, Yannick Pauchet, Kelli Hoover, Roy Kirsch, Scott M Geib, Robert F Mitchell, Robert M Waterhouse, Seung-Joon Ahn, Deanna Arsala, Joshua B Benoit, Heath Blackmon, Tiffany Bledsoe, Julia H Bowsher, André Busch, Bernarda Calla, Hsu Chao, Anna K Childers, Christopher Childers, Dave J Clarke, Lorna Cohen, Jeffery P Demuth, Huyen Dinh, HarshaVardhan Doddapaneni, Amanda Dolan, Jian J Duan, Shannon Dugan, Markus Friedrich, Karl M Glastad, Michael A D Goodisman, Stephanie Haddad, Yi Han, Daniel S T Hughes, Panagiotis Ioannidis, J Spencer Johnston, Jeffery W Jones, Leslie A Kuhn, David R Lance, Chien-Yueh Lee, Sandra L Lee, Han Lin, Jeremy A Lynch, Armin P Moczek, Shwetha C Murali, Donna M Muzny, David R Nelson, Subba R Palli, Kristen A Panfilio, Dan Pers, Monica F Poelchau, Honghu Quan, Jiaxin Qu, Ann M Ray, Joseph P Rinehart, Hugh M Robertson, Richard Roehrdanz, Andrew J Rosendale, Seunggwan Shin, Christian Silva, Alex S Torson, Iris M Vargas Jentzsch, John H Werren, Kim C Worley, George Yocum, Evgeny M Zdobnov, Richard A Gibbs, Stephen Richards
BACKGROUND: Relatively little is known about the genomic basis and evolution of wood-feeding in beetles. We undertook genome sequencing and annotation, gene expression assays, studies of plant cell wall degrading enzymes, and other functional and comparative studies of the Asian longhorned beetle, Anoplophora glabripennis, a globally significant invasive species capable of inflicting severe feeding damage on many important tree species. Complementary studies of genes encoding enzymes involved in digestion of woody plant tissues or detoxification of plant allelochemicals were undertaken with the genomes of 14 additional insects, including the newly sequenced emerald ash borer and bull-headed dung beetle...
November 11, 2016: Genome Biology
https://www.readbyqxmd.com/read/27821847/measuring-conductivity-of-living-geobacter-sulfurreducens-biofilms
#17
Matthew D Yates, Sarah M Strycharz-Glaven, Joel P Golden, Jared Roy, Stanislav Tsoi, Jeffrey S Erickson, Mohamed Y El-Naggar, Scott Calabrese Barton, Leonard M Tender
No abstract text is available yet for this article.
November 8, 2016: Nature Nanotechnology
https://www.readbyqxmd.com/read/27799513/smoking-cessation-version-1-2016-nccn-clinical-practice-guidelines-in-oncology
#18
Peter G Shields, Roy S Herbst, Douglas Arenberg, Neal L Benowitz, Laura Bierut, Julie Bylund Luckart, Paul Cinciripini, Bradley Collins, Sean David, James Davis, Brian Hitsman, Andrew Hyland, Margaret Lang, Scott Leischow, Elyse R Park, W Thomas Purcell, Jill Selzle, Andrea Silber, Sharon Spencer, Tawee Tanvetyanon, Brian Tiep, Hilary A Tindle, Reginald Tucker-Seeley, James Urbanic, Monica Webb Hooper, Benny Weksler, C Will Whitlock, Douglas E Wood, Jennifer Burns, Jillian Scavone
Cigarette smoking has been implicated in causing many cancers and cancer deaths. There is mounting evidence indicating that smoking negatively impacts cancer treatment efficacy and overall survival. The NCCN Guidelines for Smoking Cessation have been created to emphasize the importance of smoking cessation and establish an evidence-based standard of care in all patients with cancer. These guidelines provide recommendations to address smoking in patients and outlines behavioral and pharmacologic interventions for smoking cessation throughout the continuum of oncology care...
November 2016: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/27775703/dnaja1-controls-the-fate-of-misfolded-mutant-p53-through-the-mevalonate-pathway
#19
Alejandro Parrales, Atul Ranjan, Swathi V Iyer, Subhash Padhye, Scott J Weir, Anuradha Roy, Tomoo Iwakuma
Stabilization of mutant p53 (mutp53) in tumours greatly contributes to malignant progression. However, little is known about the underlying mechanisms and therapeutic approaches to destabilize mutp53. Here, through high-throughput screening we identify statins, cholesterol-lowering drugs, as degradation inducers for conformational or misfolded p53 mutants with minimal effects on wild-type p53 (wtp53) and DNA contact mutants. Statins preferentially suppress mutp53-expressing cancer cell growth. Specific reduction of mevalonate-5-phosphate by statins or mevalonate kinase knockdown induces CHIP ubiquitin ligase-mediated nuclear export, ubiquitylation, and degradation of mutp53 by impairing interaction of mutp53 with DNAJA1, a Hsp40 family member...
November 2016: Nature Cell Biology
https://www.readbyqxmd.com/read/27760113/mechanism-for-dna-transposons-to-generate-introns-on-genomic-scales
#20
Jason T Huff, Daniel Zilberman, Scott W Roy
The discovery of introns four decades ago was one of the most unexpected findings in molecular biology. Introns are sequences interrupting genes that must be removed as part of messenger RNA production. Genome sequencing projects have shown that most eukaryotic genes contain at least one intron, and frequently many. Comparison of these genomes reveals a history of long evolutionary periods during which few introns were gained, punctuated by episodes of rapid, extensive gain. However, although several detailed mechanisms for such episodic intron generation have been proposed, none has been empirically supported on a genomic scale...
October 27, 2016: Nature
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