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https://www.readbyqxmd.com/read/28502585/frontoparietal-neurostimulation-modulates-working-memory-training-benefits-and-oscillatory-synchronization
#1
Kevin T Jones, Dwight J Peterson, Kara J Blacker, Marian E Berryhill
There is considerable interest in maintaining working memory (WM) because it is essential to accomplish most cognitive tasks, and it is correlated with fluid intelligence and ecologically valid measures of daily living. Toward this end, WM training protocols aim to improve WM capacity and extend improvements to unpracticed domains, yet success is limited. One emerging approach is to couple WM training with transcranial direct current stimulation (tDCS). This pairing of WM training with tDCS in longitudinal designs promotes behavioral improvement and evidence of transfer of performance gains to untrained WM tasks...
July 15, 2017: Brain Research
https://www.readbyqxmd.com/read/28324765/hd-tdcs-in-refractory-lateral-frontal-lobe-epilepsy-patients
#2
Sanaz Ahmadi Karvigh, Mahmoud Motamedi, Mahsa Arzani, Javad Hasan Nia Roshan
PURPOSE: To evaluate the anticonvulsant effect of the novel high definition transcranial direct current stimulation (HD-tDCS) method on patients with refractory lateral frontal lobe epilepsy. The effects of HD-tDCS on working memory were also examined. METHOD: 10 adult patients with intractable lateral frontal lobe epilepsy were studied. A central cathode electrode was placed on the epileptogenic zone according to LTM, and 20-min sessions of 2mA HD-tDCS were applied for 10 consecutive days...
April 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28274831/effects-of-prefrontal-bipolar-and-high-definition-transcranial-direct-current-stimulation-on-cortical-reactivity-and-working-memory-in-healthy-adults
#3
Aron T Hill, Nigel C Rogasch, Paul B Fitzgerald, Kate E Hoy
Transcranial direct current stimulation (tDCS) is a well-recognised neuromodulatory technology which has been shown to induce short-lasting changes in motor-cortical excitability. The recent and rapid expansion of tDCS into the cognitive domain, however, necessitates deeper mechanistic understanding of its neurophysiological effects over non-motor brain regions. The present study utilised transcranial magnetic stimulation combined with electroencephalography (TMS-EEG) to probe the immediate and longer-term effects of both a bipolar (BP-tDCS) and more focal 4×1 High-Definition tDCS (HD-tDCS) montage applied over the left DLPFC on TMS-evoked potentials (TEPs) and oscillations in 19 healthy adult participants...
May 15, 2017: NeuroImage
https://www.readbyqxmd.com/read/27453334/immediate-memory-and-electrophysiologic-effects-of-prefrontal-cortex-transcranial-direct-current-stimulation-on-neurotypical-individuals-and-individuals-with-chronic-traumatic-brain-injury-a-pilot-study
#4
Therese M O'Neil-Pirozzi, Deniz Doruk, Jennifer M Thomson, Felipe Fregni
Purpose/aim: Memory impairment post-TBI is common, frequently persistent, and functionally debilitating. The purposes of this pilot study were to assess and to compare immediate behavioral auditory working memory and electrophysiologic effects of three different, randomized, conditions of left dorsolateral prefrontal cortex (LDLPFC) transcranial direct current stimulation (tDCS) applied to four neurotypical adults and four adults with chronic traumatic brain injury (TBI). MATERIALS/METHODS: Pre- and post-anodal, cathodal, and sham tDCS auditory memory performance, auditory event-related potentials (P300 amplitude and latency) and power of alpha and theta EEG bands were measured across individuals in each group...
July 2017: International Journal of Neuroscience
https://www.readbyqxmd.com/read/27065792/transcranial-direct-current-stimulation-modulates-cortical-neuronal-activity-in-alzheimer-s-disease
#5
Sara Marceglia, Simona Mrakic-Sposta, Manuela Rosa, Roberta Ferrucci, Francesca Mameli, Maurizio Vergari, Mattia Arlotti, Fabiana Ruggiero, Elio Scarpini, Daniela Galimberti, Sergio Barbieri, Alberto Priori
Quantitative electroencephalography (qEEG) showed that Alzheimer's disease (AD) is characterized by increased theta power, decreased alpha and beta power, and decreased coherence in the alpha and theta band in posterior regions. These abnormalities are thought to be associated with functional disconnections among cortical areas, death of cortical neurons, axonal pathology, and cholinergic deficits. Since transcranial Direct Current Stimulation (tDCS) over the temporo-parietal area is thought to have beneficial effects in patients with AD, in this study we aimed to investigate whether tDCS benefits are related to tDCS-induced changes in cortical activity, as represented by qEEG...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27037186/can-transcranial-direct-current-stimulation-augment-extinction-of-conditioned-fear
#6
Mascha van 't Wout, Timothy Y Mariano, Sarah L Garnaat, Madhavi K Reddy, Steven A Rasmussen, Benjamin D Greenberg
BACKGROUND: Exposure-based therapy parallels extinction learning of conditioned fear. Prior research points to the ventromedial prefrontal cortex as a potential site for the consolidation of extinction learning and subsequent retention of extinction memory. OBJECTIVE/HYPOTHESIS: The present study aimed to evaluate whether the application of non-invasive transcranial direct current stimulation (tDCS) during extinction learning enhances late extinction and early recall in human participants...
July 2016: Brain Stimulation
https://www.readbyqxmd.com/read/26903841/transcranial-direct-current-stimulation-modulates-neuronal-activity-and-learning-in-pilot-training
#7
Jaehoon Choe, Brian A Coffman, Dylan T Bergstedt, Matthias D Ziegler, Matthew E Phillips
Skill acquisition requires distributed learning both within (online) and across (offline) days to consolidate experiences into newly learned abilities. In particular, piloting an aircraft requires skills developed from extensive training and practice. Here, we tested the hypothesis that transcranial direct current stimulation (tDCS) can modulate neuronal function to improve skill learning and performance during flight simulator training of aircraft landing procedures. Thirty-two right-handed participants consented to participate in four consecutive daily sessions of flight simulation training and received sham or anodal high-definition-tDCS to the right dorsolateral prefrontal cortex (DLPFC) or left motor cortex (M1) in a randomized, double-blind experiment...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/26706985/neuromarkers-of-anxiety-and-depression-in-a-patient-after-neuro-ophthalmic-surgery-of-the-meningioma-effect-of-individually-tailored-tdcs-and-neurofeedback
#8
Andrzej Mirski, Maria Pąchalska, Marek Moskała, Michał Orski, Małgorzata Orska, Maria Miąskiewicz, Jan Zapała, Juri D Kropotov
UNLABELLED: The aim of the study was to evaluate the effectiveness of individually tailored anodal tDCs/ neurofeedback protocol for the reduction of post-operative depression after a neuroophtalmological operation of the meningioma. The neuromarkers in Quantitative EEG (QEEG) and Event-related potentials (ERPs) were utilized in the construction of protocol and evaluation. CASE DESCRIPTION: A 45-year-old female after successful neuro-ophthalmic surgery of the meningioma, complained of severe pain and anxiety, difficulties with sleeping, attention and memory problems, as well as inability to continue working in her given profession...
2015: Annals of Agricultural and Environmental Medicine: AAEM
https://www.readbyqxmd.com/read/26471400/clinical-response-to-tdcs-depends-on-residual-brain-metabolism%C3%A2-and-grey-matter-integrity-in-patients-with-minimally%C3%A2-conscious-state
#9
Aurore Thibaut, Carol Di Perri, Camille Chatelle, Marie-Aurélie Bruno, Mohamed Ali Bahri, Sarah Wannez, Andrea Piarulli, Claire Bernard, Charlotte Martial, Lizette Heine, Roland Hustinx, Steven Laureys
BACKGROUND: Transcranial direct current stimulation (tDCS) was recently shown to promote recovery of voluntary signs of consciousness in some patients in minimally conscious state (MCS). However, it remains unclear why clinical improvement is only observed in a subgroup of patients. OBJECTIVES: In this retrospective study, we investigated the relationship between tDCS responsiveness and neuroimaging data from MCS patients. METHODS: Structural Magnetic Resonance Imaging (MRI), Fluorodeoxyglucose Positron emission tomography (FDG-PET) and clinical electroencephalography (EEG) were acquired in 21 sub-acute and chronic MCS patients (8 tDCS responders) who subsequently (<48 h) received left dorsolateral prefrontal (DLPF) tDCS in a double-blind randomized cross-over trial...
November 2015: Brain Stimulation
https://www.readbyqxmd.com/read/25997999/the-effect-of-transcranial-direct-current-stimulation-on-gamma-activity-and-working-memory-in-schizophrenia
#10
Kate E Hoy, Neil W Bailey, Sara L Arnold, Paul B Fitzgerald
Working memory impairments in schizophrenia have been strongly associated with abnormalities in gamma oscillations within the dorsolateral prefrontal cortex (DLFPC). We recently published the first ever study showing that anodal transcranial Direct Current Stimulation (tDCS) to the left DLPFC was able to significantly improve working memory performance in schizophrenia. In the current paper we present a secondary analysis from this study, specifically looking at the effect of tDCS on gamma activity and its relationship to working memory...
August 15, 2015: Psychiatry Research
https://www.readbyqxmd.com/read/25795621/oscillating-square-wave-transcranial-direct-current-stimulation-tdcs-delivered-during-slow-wave-sleep-does-not-improve-declarative-memory-more-than-sham-a-randomized-sham-controlled-crossover-study
#11
RANDOMIZED CONTROLLED TRIAL
Gregory L Sahlem, Bashar W Badran, Jonathan J Halford, Nolan R Williams, Jeffrey E Korte, Kimberly Leslie, Martha Strachan, Jesse L Breedlove, Jennifer Runion, David L Bachman, Thomas W Uhde, Jeffery J Borckardt, Mark S George
BACKGROUND: A 2006 trial in healthy medical students found that anodal slow oscillating tDCS delivered bi-frontally during slow wave sleep had an enhancing effect in declarative, but not procedural memory. Although there have been supporting animal studies, and similar findings in pathological groups, this study has not been replicated, or refuted, in the intervening years. We therefore tested these earlier results for replication using similar methods with the exception of current waveform (square in our study, nearly sinusoidal in the original)...
May 2015: Brain Stimulation
https://www.readbyqxmd.com/read/25728695/spatiotemporal-neural-pattern-similarity-supports-episodic-memory
#12
Yi Lu, Changming Wang, Chuansheng Chen, Gui Xue
Formal computational models of human memory posit a central role of feature representations in episodic memory encoding and retrieval [1-4]. Correspondingly, fMRI studies have found that, in addition to activity level [5, 6], the neural activation pattern similarity across repetitions (i.e., self-similarity) was greater for subsequently remembered than forgotten items [7-9]. This self-similarity has been suggested to reflect pattern reinstatement due to study-phase retrieval [7, 10, 11]. However, the low temporal resolution of fMRI measures could determine neither the temporal precision of study-phase reinstatement nor the processing stage at which the reinstatement supported subsequent memory [12]...
March 16, 2015: Current Biology: CB
https://www.readbyqxmd.com/read/25389394/enhancement-of-sleep-slow-waves-underlying-mechanisms-and-practical-consequences
#13
Michele Bellesi, Brady A Riedner, Gary N Garcia-Molina, Chiara Cirelli, Giulio Tononi
Even modest sleep restriction, especially the loss of sleep slow wave activity (SWA), is invariably associated with slower electroencephalogram (EEG) activity during wake, the occurrence of local sleep in an otherwise awake brain, and impaired performance due to cognitive and memory deficits. Recent studies not only confirm the beneficial role of sleep in memory consolidation, but also point to a specific role for sleep slow waves. Thus, the implementation of methods to enhance sleep slow waves without unwanted arousals or lightening of sleep could have significant practical implications...
2014: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/24947595/cumulative-effects-of-transcranial-direct-current-stimulation-on-eeg-oscillations-and-attention-working-memory-during-subacute-neurorehabilitation-of-traumatic-brain-injury
#14
RANDOMIZED CONTROLLED TRIAL
F Ulam, C Shelton, L Richards, L Davis, B Hunter, F Fregni, K Higgins
OBJECTIVE: To investigate in a randomized, double-blind design, cumulative effects of anodal tDCS on EEG oscillations and neuropsychological tests among patients with traumatic brain injury (TBI) undergoing subacute neurorehabilitation. METHODS: Twenty-six patients were randomly assigned to active (n=13) or sham (n=13) tDCS groups. EEGs were recorded at 6 different time points, assessing both immediate and cumulative effects of tDCS on EEG oscillations. Twenty minute sessions of 1mA anodal stimulation to the left dorsolateral prefrontal cortex (F3, cathode placed at right supraorbital site, Fp2), were provided on 10 consecutive days...
March 2015: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/24914953/modulation-of-cortical-activity-by-transcranial-direct-current-stimulation-in-patients-with-affective-disorder
#15
Tamara Y Powell, Tjeerd W Boonstra, Donel M Martin, Colleen K Loo, Michael Breakspear
Transcranial direct current stimulation (tDCS) has been shown to have antidepressant efficacy in patients experiencing a major depressive episode, but little is known about the underlying neurophysiology. The purpose of our study was to investigate the acute effects of tDCS on cortical activity using electroencephalography (EEG) in patients with an affective disorder. Eighteen patients diagnosed with an affective disorder and experiencing a depressive episode participated in a sham-controlled study of tDCS, each receiving a session of active (2 mA for 20 minutes) and sham tDCS to the left dorsolateral prefrontal cortex (DLPFC)...
2014: PloS One
https://www.readbyqxmd.com/read/24698973/transcranial-slow-oscillation-stimulation-during-sleep-enhances-memory-consolidation-in-rats
#16
Sonja Binder, Karolin Berg, Fernando Gasca, Belen Lafon, Lucas C Parra, Jan Born, Lisa Marshall
BACKGROUND: The importance of slow-wave sleep (SWS), hallmarked by the occurrence of sleep slow oscillations (SO), for the consolidation of hippocampus-dependent memories has been shown in numerous studies. Previously, the application of transcranial direct current stimulation, oscillating at the frequency of endogenous slow oscillations, during SWS enhanced memory consolidation for a hippocampus dependent task in humans suggesting a causal role of slowly oscillating electric fields for sleep dependent memory consolidation...
July 2014: Brain Stimulation
https://www.readbyqxmd.com/read/24579831/working-memory-training-with-tdcs-improves-behavioral-and-neurophysiological-symptoms-in-pilot-group-with-post-traumatic-stress-disorder-ptsd-and-with-poor-working-memory
#17
Nerida Saunders, Russell Downham, Bulent Turman, Juri Kropotov, Richard Clark, Rustam Yumash, Arielle Szatmary
This pilot study investigated the feasibility of treating people suffering from both post-traumatic stress disorder (PTSD) and poor working memory by employing a combination of computerized working memory training and transcranial direct current stimulation (tDCS). After treatment, all four participants showed clinically significant improvements on a range of cognitive and emotional performance measures. Moreover, these improvements were accompanied by theoretically significant neurophysiological changes between pre- and post-treatment electroencephalographic (EEG) recordings...
2015: Neurocase
https://www.readbyqxmd.com/read/24409131/transcranial-slow-oscillation-stimulation-during-nrem-sleep-enhances-acquisition-of-the-radial-maze-task-and-modulates-cortical-network-activity-in-rats
#18
Sonja Binder, Julia Rawohl, Jan Born, Lisa Marshall
Slow wave sleep, hallmarked by the occurrence of slow oscillations (SO), plays an important role for the consolidation of hippocampus-dependent memories. Transcranial stimulation by weak electric currents oscillating at the endogenous SO frequency (SO-tDCS) during post-learning sleep was previously shown by us to boost SO activity and improve the consolidation of hippocampus-dependent memory in human subjects. Here, we aimed at replicating and extending these results to a rodent model. Rats were trained for 12 days at the beginning of their inactive phase in the reference memory version of the radial arm maze...
2013: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/23810208/no-effects-of-slow-oscillatory-transcranial-direct-current-stimulation-tdcs-on-sleep-dependent-memory-consolidation-in-healthy-elderly-subjects
#19
RANDOMIZED CONTROLLED TRIAL
Torsten Eggert, Hans Dorn, Cornelia Sauter, Michael A Nitsche, Malek Bajbouj, Heidi Danker-Hopfe
BACKGROUND: Studies in young healthy volunteers provided evidence of a beneficial impact of an anodal time-varied transcranial direct current stimulation (tDCS) during early slow wave rich sleep on declarative memory but not on procedural memory. OBJECTIVE/HYPOTHESIS: The present study investigated whether sleep-dependent memory consolidation can also be affected by slow oscillating tDCS in a population of elderly subjects. METHODS: 26 subjects (69...
November 2013: Brain Stimulation
https://www.readbyqxmd.com/read/23751169/testing-the-limits-investigating-the-effect-of-tdcs-dose-on-working-memory-enhancement-in-healthy-controls
#20
Kate E Hoy, Melanie R L Emonson, Sara L Arnold, Richard H Thomson, Zafiris J Daskalakis, Paul B Fitzgerald
Transcranial Direct Current Stimulation (tDCS) is a non-invasive form of brain stimulation which has been shown to induce changes in brain activity and subsequent functioning. In particular, there is a rapidly growing evidence base showing that anodal tDCS applied to the left prefrontal cortex (PFC) is able to enhance aspects of cognitive functioning, in particular working memory (WM). This has led to both excitement and concerns regarding the possibility of 'electrodoping' in order to greatly improve one's cognitive performance...
August 2013: Neuropsychologia
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