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https://www.readbyqxmd.com/read/27765610/neural-signature-of-tdcs-tpcs-and-their-combination-comparing-the-effects-on-neural-plasticity
#1
Thibaut Aurore, Russo Cristina, Morales-Quezada Leon, Hurtado-Puerto Aura, Deitos Alícia, Steven Freedman, Carvalho Sandra, Fregni Felipe
Transcranial pulsed current stimulation (tPCS) and transcranial direct current stimulation (tDCS) are two noninvasive neuromodulatory brain stimulation techniques whose effects on human brain and behavior have been studied individually. In the present study we aimed to quantify the effects of tDCS and tPCS, individually and in combination, on cortical activity, sensitivity and pain-related assessments in healthy individuals in order to understand their neurophysiological mechanisms and potential applications in clinical populations...
October 17, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27729853/feasibility-of-non-invasive-brain-modulation-for-management-of-pain-related-to-chemoradiotherapy-in-patients-with-advanced-head-and-neck-cancer
#2
Xiao-Su Hu, Clayton A Fisher, Stephanie M Munz, Rebecca L Toback, Thiago D Nascimento, Emily L Bellile, Laura Rozek, Avraham Eisbruch, Francis P Worden, Theodora E Danciu, Alexandre F DaSilva
Patients with head and neck cancer often experience a significant decrease in their quality of life during chemoradiotherapy (CRT) due to treatment-related pain, which is frequently classified as severe. Transcranial direct current stimulation (tDCS) is a method of non-invasive brain stimulation that has been frequently used in experimental and clinical pain studies. In this pilot study, we investigated the clinical impact and central mechanisms of twenty primary motor cortex (M1) stimulation sessions with tDCS during 7 weeks of CRT for head and neck cancer...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27453334/immediate-memory-and-electrophysiologic-effects-of-prefrontal-cortex-transcranial-direct-current-stimulation-on-neurotypical-individuals-and-individuals-with-chronic-traumatic-brain-injury-a-pilot-study
#3
Therese M O'Neil-Pirozzi, Deniz Doruk, Jennifer M Thomson, Felipe Fregni
PURPOSE/AIM: Memory impairment post-TBI is common, frequently persistent, and functionally debilitating. The purposes of this pilot study were to assess and to compare immediate behavioral auditory working memory and electrophysiologic effects of three different, randomized, conditions of left dorsolateral prefrontal cortex (LDLPFC) transcranial direct current stimulation (tDCS) applied to four neurotypical adults and four adults with chronic traumatic brain injury (TBI). MATERIALS/METHODS: Pre- and post- anodal, cathodal, and sham tDCS auditory memory performance, auditory event-related potentials (P300 amplitude and latency) and power of alpha and theta EEG bands were measured across individuals in each group...
July 24, 2016: International Journal of Neuroscience
https://www.readbyqxmd.com/read/27450765/the-effect-of-transcranial-direct-current-stimulation-on-seizure-frequency-of-patients-with-mesial-temporal-lobe-epilepsy-with-hippocampal-sclerosis
#4
Pinar Tekturk, Ezgi Tuna Erdogan, Adnan Kurt, Ebru Nur Vanli-Yavuz, Esme Ekizoglu, Ece Kocagoncu, Zeynep Kucuk, Serkan Aksu, Nerses Bebek, Zuhal Yapici, Candan Gurses, Aysen Gokyigit, Betul Baykan, Sacit Karamursel
OBJECTIVES: Transcranial direct current stimulation (tDCS) is a non-invasive and safe method tried in drug-resistant epilepsies, in recent years. Our aim was to evaluate the effect of tDCS in patients diagnosed with mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) which is a well-known drug-resistant focal epilepsy syndrome. PATIENTS AND METHODS: Twelve MTLE-HS patients diagnosed with their typical clinical, EEG and MRI findings fulfilling the criteria for drug-resistance as suggested by the ILAE commission were included after Ethics Committee approval and their signed consent...
October 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/27445739/does-a-combination-of-virtual-reality-neuromodulation-and-neuroimaging-provide-a-comprehensive-platform-for-neurorehabilitation-a-narrative-review-of-the-literature
#5
REVIEW
Wei-Peng Teo, Makii Muthalib, Sami Yamin, Ashlee M Hendy, Kelly Bramstedt, Eleftheria Kotsopoulos, Stephane Perrey, Hasan Ayaz
In the last decade, virtual reality (VR) training has been used extensively in video games and military training to provide a sense of realism and environmental interaction to its users. More recently, VR training has been explored as a possible adjunct therapy for people with motor and mental health dysfunctions. The concept underlying VR therapy as a treatment for motor and cognitive dysfunction is to improve neuroplasticity of the brain by engaging users in multisensory training. In this review, we discuss the theoretical framework underlying the use of VR as a therapeutic intervention for neurorehabilitation and provide evidence for its use in treating motor and mental disorders such as cerebral palsy, Parkinson's disease, stroke, schizophrenia, anxiety disorders, and other related clinical areas...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27378836/computational-pipeline-for-nirs-eeg-joint-imaging-of-tdcs-evoked-cerebral-responses-an-application-in-ischemic-stroke
#6
Debarpan Guhathakurta, Anirban Dutta
Transcranial direct current stimulation (tDCS) modulates cortical neural activity and hemodynamics. Electrophysiological methods (electroencephalography-EEG) measure neural activity while optical methods (near-infrared spectroscopy-NIRS) measure hemodynamics coupled through neurovascular coupling (NVC). Assessment of NVC requires development of NIRS-EEG joint-imaging sensor montages that are sensitive to the tDCS affected brain areas. In this methods paper, we present a software pipeline incorporating freely available software tools that can be used to target vascular territories with tDCS and develop a NIRS-EEG probe for joint imaging of tDCS-evoked responses...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27375462/change-in-mean-frequency-of-resting-state-electroencephalography-after-transcranial-direct-current-stimulation
#7
Tjeerd W Boonstra, Stevan Nikolin, Ann-Christin Meisener, Donel M Martin, Colleen K Loo
Transcranial direct current stimulation (tDCS) is proposed as a tool to investigate cognitive functioning in healthy people and as a treatment for various neuropathological disorders. However, the underlying cortical mechanisms remain poorly understood. We aim to investigate whether resting-state electroencephalography (EEG) can be used to monitor the effects of tDCS on cortical activity. To this end we tested whether the spectral content of ongoing EEG activity is significantly different after a single session of active tDCS compared to sham stimulation...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27303311/transcranial-electrical-neuromodulation-based-on-the-reciprocity-principle
#8
Mariano Fernández-Corazza, Sergei Turovets, Phan Luu, Erik Anderson, Don Tucker
A key challenge in multi-electrode transcranial electrical stimulation (TES) or transcranial direct current stimulation (tDCS) is to find a current injection pattern that delivers the necessary current density at a target and minimizes it in the rest of the head, which is mathematically modeled as an optimization problem. Such an optimization with the Least Squares (LS) or Linearly Constrained Minimum Variance (LCMV) algorithms is generally computationally expensive and requires multiple independent current sources...
2016: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/27268424/assessing-cortical-synchronization-during-transcranial-direct-current-stimulation-a-graph-theoretical-analysis
#9
Matteo Mancini, Debora Brignani, Silvia Conforto, Piercarlo Mauri, Carlo Miniussi, Maria Concetta Pellicciari
Transcranial direct current stimulation (tDCS) is a neuromodulation technique that can alter cortical excitability and modulate behaviour in a polarity-dependent way. Despite the widespread use of this method in the neuroscience field, its effects on ongoing local or global (network level) neuronal activity are still not foreseeable. A way to shed light on the neuronal mechanisms underlying the cortical connectivity changes induced by tDCS is provided by the combination of tDCS with electroencephalography (EEG)...
October 15, 2016: NeuroImage
https://www.readbyqxmd.com/read/27172063/a-simple-method-for-eeg-guided-transcranial-electrical-stimulation-without-models
#10
Andrea Cancelli, Carlo Cottone, Franca Tecchio, Dennis Q Truong, Jacek Dmochowski, Marom Bikson
OBJECTIVE: There is longstanding interest in using EEG measurements to inform transcranial Electrical Stimulation (tES) but adoption is lacking because users need a simple and adaptable recipe. The conventional approach is to use anatomical head-models for both source localization (the EEG inverse problem) and current flow modeling (the tES forward model), but this approach is computationally demanding, requires an anatomical MRI, and strict assumptions about the target brain regions...
June 2016: Journal of Neural Engineering
https://www.readbyqxmd.com/read/27143601/modulation-of-total-sleep-time-by-transcranial-direct-current-stimulation-tdcs
#11
Lukas Frase, Hannah Piosczyk, Sulamith Zittel, Friederike Jahn, Peter Selhausen, Lukas Krone, Bernd Feige, Florian Mainberger, Jonathan G Maier, Marion Kuhn, Stefan Klöppel, Claus Normann, Annette Sterr, Kai Spiegelhalder, Dieter Riemann, Michael A Nitsche, Christoph Nissen
Arousal and sleep are fundamental physiological processes, and their modulation is of high clinical significance. This study tested the hypothesis that total sleep time (TST) in humans can be modulated by the non-invasive brain stimulation technique transcranial direct current stimulation (tDCS) targeting a 'top-down' cortico-thalamic pathway of sleep-wake regulation. Nineteen healthy participants underwent a within-subject, repeated-measures protocol across five nights in the sleep laboratory with polysomnographic monitoring (adaptation, baseline, three experimental nights)...
September 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27132485/modulation-of-neurophysiological-auditory-processing-measures-by-bilateral-transcranial-direct-current-stimulation-in-schizophrenia
#12
Walter Dunn, Yuri Rassovsky, Jonathan K Wynn, Allan D Wu, Marco Iacoboni, Gerhard Hellemann, Michael F Green
This study used bilateral transcranial direct current stimulation (tDCS) to target neural generators of auditory Mismatch Negativity (MMN) and oddball P300 in schizophrenia patients. tDCS was applied to the pre-frontal cortex in a parallel between-group design. There was a significant main effect of stimulation resulting in modulation of MMN amplitude. This effect was mainly driven by a non-significant, but large, effect-size decrease in MMN amplitude with anodal stimulation. This is the first study to demonstrate that tDCS is able to engage and modulate an EEG-based auditory processing measure in schizophrenia...
July 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/27065792/transcranial-direct-current-stimulation-modulates-cortical-neuronal-activity-in-alzheimer-s-disease
#13
Sara Marceglia, Simona Mrakic-Sposta, Manuela Rosa, Roberta Ferrucci, Francesca Mameli, Maurizio Vergari, Mattia Arlotti, Fabiana Ruggiero, Elio Scarpini, Daniela Galimberti, Sergio Barbieri, Alberto Priori
Quantitative electroencephalography (qEEG) showed that Alzheimer's disease (AD) is characterized by increased theta power, decreased alpha and beta power, and decreased coherence in the alpha and theta band in posterior regions. These abnormalities are thought to be associated with functional disconnections among cortical areas, death of cortical neurons, axonal pathology, and cholinergic deficits. Since transcranial Direct Current Stimulation (tDCS) over the temporo-parietal area is thought to have beneficial effects in patients with AD, in this study we aimed to investigate whether tDCS benefits are related to tDCS-induced changes in cortical activity, as represented by qEEG...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27059880/transcranial-direct-current-stimulation-of-the-prefrontal-cortex-increases-attention-to-visual-target-stimuli
#14
Nina Vierheilig, Andreas Mühlberger, Thomas Polak, Martin J Herrmann
Both functional imaging or EEG studies and studies including neurological patients found the dorsolateral prefrontal cortex (dLPFC) to be an important brain area for the processing of emotion and attention. The aim of the present study was to investigate whether emotion and attention can be modulated through bilateral transcranial direct current stimulation (tDCS) of the dLPFC. Therefore, we measured electroencephalographic occipital (early posterior negativity, EPN) and parietal ERPs (late positive potential, LPP) during an emotional picture viewing paradigm with an additional attentional instruction while applying bilateral anodal and cathodal tDC-stimulation to the left and right dLPFC...
October 2016: Journal of Neural Transmission
https://www.readbyqxmd.com/read/27058150/brain-signal-complexity-rises-with-repetition-suppression-in-visual-learning
#15
Marc Philippe Lafontaine, Karine Lacourse, Jean-Marc Lina, Anthony R McIntosh, Frédéric Gosselin, Hugo Théoret, Sarah Lippé
Neuronal activity associated with visual processing of an unfamiliar face gradually diminishes when it is viewed repeatedly. This process, known as repetition suppression (RS), is involved in the acquisition of familiarity. Current models suggest that RS results from interactions between visual information processing areas located in the occipito-temporal cortex and higher order areas, such as the dorsolateral prefrontal cortex (DLPFC). Brain signal complexity, which reflects information dynamics of cortical networks, has been shown to increase as unfamiliar faces become familiar...
June 21, 2016: Neuroscience
https://www.readbyqxmd.com/read/27039705/physiological-processes-non-linearly-affect-electrophysiological-recordings-during-transcranial-electric-stimulation
#16
Nima Noury, Joerg F Hipp, Markus Siegel
Transcranial electric stimulation (tES) is a promising tool to non-invasively manipulate neuronal activity in the human brain. Several studies have shown behavioral effects of tES, but stimulation artifacts complicate the simultaneous investigation of neural activity with EEG or MEG. Here, we first show for EEG and MEG, that contrary to previous assumptions, artifacts do not simply reflect stimulation currents, but that heartbeat and respiration non-linearly modulate stimulation artifacts. These modulations occur irrespective of the stimulation frequency, i...
October 15, 2016: NeuroImage
https://www.readbyqxmd.com/read/27037186/can-transcranial-direct-current-stimulation-augment-extinction-of-conditioned-fear
#17
Mascha van 't Wout, Timothy Y Mariano, Sarah L Garnaat, Madhavi K Reddy, Steven A Rasmussen, Benjamin D Greenberg
BACKGROUND: Exposure-based therapy parallels extinction learning of conditioned fear. Prior research points to the ventromedial prefrontal cortex as a potential site for the consolidation of extinction learning and subsequent retention of extinction memory. OBJECTIVE/HYPOTHESIS: The present study aimed to evaluate whether the application of non-invasive transcranial direct current stimulation (tDCS) during extinction learning enhances late extinction and early recall in human participants...
July 2016: Brain Stimulation
https://www.readbyqxmd.com/read/26964682/electrical-stimulation-of-the-frontal-cortex-enhances-slow-frequency-eeg-activity-and-sleepiness
#18
A D'Atri, E De Simoni, M Gorgoni, M Ferrara, F Ferlazzo, P M Rossini, L De Gennaro
Our aim was to enhance the spontaneous slow-frequency EEG activity during the resting state using oscillating transcranial direct currents (tDCS) with a stimulation frequency that resembles the spontaneous oscillations of sleep onset. Accordingly, in this preliminary study, we assessed EEG after-effects of a frontal oscillatory tDCS with different frequency (0.8 vs. 5 Hz) and polarity (anodal, cathodal, and sham). Two single-blind experiments compared the after effects on the resting EEG of oscillatory tDCS [Exp...
June 2, 2016: Neuroscience
https://www.readbyqxmd.com/read/26903841/transcranial-direct-current-stimulation-modulates-neuronal-activity-and-learning-in-pilot-training
#19
Jaehoon Choe, Brian A Coffman, Dylan T Bergstedt, Matthias D Ziegler, Matthew E Phillips
Skill acquisition requires distributed learning both within (online) and across (offline) days to consolidate experiences into newly learned abilities. In particular, piloting an aircraft requires skills developed from extensive training and practice. Here, we tested the hypothesis that transcranial direct current stimulation (tDCS) can modulate neuronal function to improve skill learning and performance during flight simulator training of aircraft landing procedures. Thirty-two right-handed participants consented to participate in four consecutive daily sessions of flight simulation training and received sham or anodal high-definition-tDCS to the right dorsolateral prefrontal cortex (DLPFC) or left motor cortex (M1) in a randomized, double-blind experiment...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/26883068/transcranial-direct-current-stimulation-changes-resting-state-functional-connectivity-a-large-scale-brain-network-modeling-study
#20
Tim Kunze, Alexander Hunold, Jens Haueisen, Viktor Jirsa, Andreas Spiegler
Transcranial direct current stimulation (tDCS) is a noninvasive technique for affecting brain dynamics with promising application in the clinical therapy of neurological and psychiatric disorders such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Resting state dynamics increasingly play a role in the assessment of connectivity-based pathologies such as Alzheimer's and schizophrenia. We systematically applied tDCS in a large-scale network model of 74 cerebral areas, investigating the spatiotemporal changes in dynamic states as a function of structural connectivity changes...
October 15, 2016: NeuroImage
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