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Dementia language tdcs

Maria Cotelli, Rosa Manenti, Donata Paternicò, Maura Cosseddu, Michela Brambilla, Michela Petesi, Enrico Premi, Roberto Gasparotti, Orazio Zanetti, Alessandro Padovani, Barbara Borroni
Agrammatic variant primary progressive aphasia is a neurodegenerative disorder specifically characterized by language deficits. A recent study has demonstrated a beneficial effect of transcranial direct current stimulation (tDCS) in combination with language training on naming accuracy in these patients. The aim of the study was to evaluate whether the improvement of naming accuracy after tDCS during language training was related to regional grey matter (GM) density. Eighteen avPPA patients underwent a brain magnetic resonance imaging before receiving a treatment that consisted of tDCS over the left dorsolateral prefrontal cortex during individualized language training (10 daily therapy sessions, 5 days per week from Monday to Friday)...
September 2016: Brain Topography
D Antonenko, A Flöel
Transcranial direct current stimulation (tDCS) has been successfully used in neuroscientific research to modulate cognitive functions. Recent studies suggested that improvement of behavioral performance is associated with tDCS-induced modulation of neuronal activity and connectivity. Thus, tDCS may also represent a promising tool for reconstitution of cognitive functions in the context of memory decline related to Alzheimer's disease or aphasia following stroke; however, evidence from randomized sham-controlled clinical trials is still scarce...
August 2016: Der Nervenarzt
Rosa Manenti, Marta Bianchi, Maura Cosseddu, Michela Brambilla, Cristina Rizzetti, Alessandro Padovani, Barbara Borroni, Maria Cotelli
BACKGROUND: Corticobasal Syndrome (CBS) is a neurodegenerative disorder that overlaps both clinically and neuropathologically with Frontotemporal dementia (FTD) and is characterized by apraxia, alien limb phenomena, cortical sensory loss, cognitive impairment, behavioral changes and aphasia. It has been recently demonstrated that transcranial direct current stimulation (tDCS) improves naming in healthy subjects and in subjects with language deficits. OBJECTIVE: The aim of the present study was to explore the extent to which anodal tDCS over the parietal cortex (PARC) could facilitate naming performance in CBS subjects...
2015: Frontiers in Aging Neuroscience
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