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https://www.readbyqxmd.com/read/28340464/a-review-on-various-electrochemical-techniques-for-heavy-metal-ions-detection-with-different-sensing-platforms
#1
REVIEW
BabanKumar Bansod, Tejinder Kumar, Ritula Thakur, Shakshi Rana, Inderbir Singh
Heavy metal ions are non-biodegradable and contaminate most of the natural resources occurring in the environment including water. Some of the heavy metals including Lead (Pb), Mercury (Hg), Arsenic (As), Chromium (Cr) and Cadmium (Cd) are considered to be highly toxic and hazardous to human health even at trace levels. This leads to the requirement of fast, accurate and reliable techniques for the detection of heavy metal ions. This review presents various electrochemical detection techniques for heavy metal ions those are user friendly, low cost, provides on-site and real time monitoring as compared to other spectroscopic and optical techniques...
March 18, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28340107/association-between-the-application-of-iso-9001-2008-alone-or-in-combination-with-health-specific-standards-and-quality-related-activities-in-hungarian-hospitals
#2
Viktor Dombrádi, Orsolya Karola Csenteri, János Sándor, Sándor Godény
Objective: To investigate how International Organization for Standardization (ISO) 9001 and the Hungarian Health Care Standards (HHCS) certifications are associated with quality management, patient safety, patient rights and human resource management activities. Design: A cross-sectional study was implemented using the 2009 Hungarian hospital survey's database. Setting: Hungary. Participants: Fifty-three general hospitals were included in the statistical analysis...
March 7, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28339420/a-pilot-study-of-a-worksite-based-participatory-intervention-program-its-acceptability-and-short-term-effects-on-work-climate-and-attitudes-in-human-service-employees
#3
Eva Charlotta Nylén, Petra Lindfors, Lars Ishäll, Sara Göransson, Gunnar Aronsson, Camilla Kylin, Magnus Sverke
BACKGROUND: Psychosocial factors, including job demands and poor resources, have been linked to stress, health problems, and negative job attitudes. However, worksite based interventions and programs targeting psychosocial factors may change employees' perceptions of their work climate and work attitudes. OBJECTIVE: This pilot study describes a newly developed worksite based participatory organizational intervention program that was tested in the social service sector...
March 23, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28335580/the-development-of-psychiatric-services-providing-an-alternative-to-full-time-hospitalization-is-associated-with-shorter-length-of-stay-in-french-public-psychiatry
#4
Coralie Gandré, Jeanne Gervaix, Julien Thillard, Jean-Marc Macé, Jean-Luc Roelandt, Karine Chevreul
International recommendations for mental health care have advocated for a reduction in the length of stay (LOS) in full-time hospitalization and the development of alternatives to full-time hospitalizations (AFTH) could facilitate alignment with those recommendations. Our objective was therefore to assess whether the development of AFTH in French psychiatric sectors was associated with a reduction in the LOS in full-time hospitalization. Using data from the French national discharge database of psychiatric care, we computed the LOS of patients admitted for full-time hospitalization...
March 21, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28335444/hiv-education-and-welfare-services-in-primary-care-an-empirical-model-of-integration-in-brazil-s-unified-health-system
#5
Rahbel Rahman, Rogério M Pinto, Melanie M Wall
Integration of health education and welfare services in primary care systems is a key strategy to solve the multiple determinants of chronic diseases, such as Human Immunodeficiency Virus Infection and Acquired Immune Deficiency Syndrome (HIV/AIDS). However, there is a scarcity of conceptual models from which to build integration strategies. We provide a model based on cross-sectional data from 168 Community Health Agents, 62 nurses, and 32 physicians in two municipalities in Brazil's Unified Health System (UHS)...
March 14, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28335428/an-updated-review-of-ciguatera-fish-poisoning-clinical-epidemiological-environmental-and-public-health-management
#6
REVIEW
Melissa A Friedman, Mercedes Fernandez, Lorraine C Backer, Robert W Dickey, Jeffrey Bernstein, Kathleen Schrank, Steven Kibler, Wendy Stephan, Matthew O Gribble, Paul Bienfang, Robert E Bowen, Stacey Degrasse, Harold A Flores Quintana, Christopher R Loeffler, Richard Weisman, Donna Blythe, Elisa Berdalet, Ram Ayyar, Danielle Clarkson-Townsend, Karen Swajian, Ronald Benner, Tom Brewer, Lora E Fleming
Ciguatera Fish Poisoning (CFP) is the most frequently reported seafood-toxin illness in the world. It causes substantial human health, social, and economic impacts. The illness produces a complex array of gastrointestinal, neurological and neuropsychological, and cardiovascular symptoms, which may last days, weeks, or months. This paper is a general review of CFP including the human health effects of exposure to ciguatoxins (CTXs), diagnosis, human pathophysiology of CFP, treatment, detection of CTXs in fish, epidemiology of the illness, global dimensions, prevention, future directions, and recommendations for clinicians and patients...
March 14, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28334828/flexible-crispr-library-construction-using-parallel-oligonucleotide-retrieval
#7
Abigail Read, Shaojian Gao, Eric Batchelor, Ji Luo
CRISPR/Cas9-based gene knockout libraries have emerged as a powerful tool for functional screens. We present here a set of pre-designed human and mouse sgRNA sequences that are optimized for both high on-target potency and low off-target effect. To maximize the chance of target gene inactivation, sgRNAs were curated to target both 5΄ constitutive exons and exons that encode conserved protein domains. We describe here a robust and cost-effective method to construct multiple small sized CRISPR library from a single oligo pool generated by array synthesis using parallel oligonucleotide retrieval...
March 16, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28334812/understanding-collaboration-in-general-practice-a-qualitative-study
#8
Susan McInnes, Kath Peters, Andrew Bonney, Elizabeth Halcomb
Background.: An increased incidence of chronic and complex conditions in the community is placing pressure on human resources in general practice. Improving collaboration between GPs and registered nurses may help alleviate workforce stressors and enhance health outcomes. Objective.: To explore the facilitators and challenges of collaboration between GPs and registered nurses in Australian general practice. Methods.: Eight GPs and 14 registered nurses from general practices in New South Wales, Australia, participated in semi-structured face-to-face interviews...
March 8, 2017: Family Practice
https://www.readbyqxmd.com/read/28334697/constraint-based-stoichiometric-modelling-from-single-organisms-to-microbial-communities
#9
REVIEW
Willi Gottstein, Brett G Olivier, Frank J Bruggeman, Bas Teusink
Microbial communities are ubiquitously found in Nature and have direct implications for the environment, human health and biotechnology. The species composition and overall function of microbial communities are largely shaped by metabolic interactions such as competition for resources and cross-feeding. Although considerable scientific progress has been made towards mapping and modelling species-level metabolism, elucidating the metabolic exchanges between microorganisms and steering the community dynamics remain an enormous scientific challenge...
November 2016: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28334554/rapid-establishment-of-the-european-bank-for-induced-pluripotent-stem-cells-ebisc-the-hot-start-experience
#10
Paul A De Sousa, Rachel Steeg, Elisabeth Wachter, Kevin Bruce, Jason King, Marieke Hoeve, Shalinee Khadun, George McConnachie, Julie Holder, Andreas Kurtz, Stefanie Seltmann, Johannes Dewender, Sascha Reimann, Glyn Stacey, Orla O'Shea, Charlotte Chapman, Lyn Healy, Heiko Zimmermann, Bryan Bolton, Trisha Rawat, Isobel Atkin, Anna Veiga, Bernd Kuebler, Blanca Miranda Serano, Tomo Saric, Jürgen Hescheler, Oliver Brüstle, Michael Peitz, Cornelia Thiele, Niels Geijsen, Bjørn Holst, Christian Clausen, Majlinda Lako, Lyle Armstrong, Shailesh K Gupta, Alexander J Kvist, Ryan Hicks, Anna Jonebring, Gabriella Brolén, Andreas Ebneth, Alfredo Cabrera-Socorro, Patrik Foerch, Martine Geraerts, Tina C Stummann, Shawn Harmon, Carol George, Ian Streeter, Laura Clarke, Helen Parkinson, Peter W Harrison, Adam Faulconbridge, Luca Cherubin, Tony Burdett, Cesar Trigueros, Minal J Patel, Christa Lucas, Barry Hardy, Rok Predan, Joh Dokler, Maja Brajnik, Oliver Keminer, Ole Pless, Philip Gribbon, Carsten Claussen, Annette Ringwald, Beate Kreisel, Aidan Courtney, Timothy E Allsopp
A fast track "Hot Start" process was implemented to launch the European Bank for Induced Pluripotent Stem Cells (EBiSC) to provide early release of a range of established control and disease linked human induced pluripotent stem cell (hiPSC) lines. Established practice amongst consortium members was surveyed to arrive at harmonised and publically accessible Standard Operations Procedures (SOPs) for tissue procurement, bio-sample tracking, iPSC expansion, cryopreservation, qualification and distribution to the research community...
March 7, 2017: Stem Cell Research
https://www.readbyqxmd.com/read/28334399/association-of-hiv-status-with-local-immune-response-to-anal-squamous-cell-carcinoma-implications-for-immunotherapy
#11
Elizabeth L Yanik, Genevieve J Kaunitz, Tricia R Cottrell, Farah Succaria, Tracee L McMiller, Maria L Ascierto, Jessica Esandrio, Haiying Xu, Aleksandra Ogurtsova, Toby Cornish, Evan J Lipson, Suzanne L Topalian, Eric A Engels, Janis M Taube
Importance: The programmed cell death protein 1 (PD-1) and programmed death-ligand 1 (PD-L1) pathway play an important immunosuppressive role in cancer and chronic viral infection, and have been effectively targeted in cancer therapy. Anal squamous cell carcinoma (SCC) is associated with both human papillomavirus and HIV infection. To date, patients with HIV have been excluded from most trials of immune checkpoint blocking agents, such as anti-PD-1 and anti-PD-L1, because it was assumed that their antitumor immunity was compromised compared with immunocompetent patients...
March 23, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28333537/self-control-depletion-and-nicotine-deprivation-as-precipitants-of-smoking-cessation-failure-a-human-laboratory-model
#12
Bryan W Heckman, David A MacQueen, Nicole S Marquinez, James MacKillop, Warren K Bickel, Thomas H Brandon
OBJECTIVE: The need to understand potential precipitants of smoking relapse is exemplified by relapse rates as high as 95%. The Self-Control Strength model, which proposes that self-control is dependent upon limited resources and susceptible to fatigue, may offer insight into relapse processes. The current study tested the hypothesis that self-control depletion (SCD), produced from engagement in emotional suppression, would serve as a novel antecedent for cessation failure, as indexed by a validated laboratory analogue of smoking lapse and relapse...
April 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28333338/drug-discovery-for-male-subfertility-using-high-throughput-screening-a-new-approach-to-an-unsolved-problem
#13
Sarah J Martins da Silva, Sean G Brown, Keith Sutton, Louise V King, Halil Ruso, David W Gray, Paul G Wyatt, Mark C Kelly, Christopher L R Barratt, Anthony G Hope
STUDY QUESTION: Can pharma drug discovery approaches be utilized to transform investigation into novel therapeutics for male infertility? SUMMARY ANSWER: High-throughput screening (HTS) is a viable approach to much-needed drug discovery for male factor infertility. WHAT IS KNOWN ALREADY: There is both huge demand and a genuine clinical need for new treatment options for infertile men. However, the time, effort and resources required for drug discovery are currently exorbitant, due to the unique challenges of the cellular, physical and functional properties of human spermatozoa and a lack of appropriate assay platform...
March 16, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28332819/a-path-to-impact-for-autonomous-field-deployable-chemical-sensors-a-case-study-of-in-situ-nitrite-sensors
#14
Tim M Schierenbeck, Matthew C Smith
Natural freshwater systems have been severely affected by excess loading of macronutrients (e.g., nitrogen and phosphorous) from fertilizers, fossil fuels, and human and livestock waste. In the USA, impacts to drinking water quality, biogeochemical cycles, and aquatic ecosystems are estimated to cost US$210 billion annually. Field-deployable nutrient sensors (FDS) offer potential to support research and resource management efforts by acquiring higher resolution data than are currently supported by expensive conventional sampling methods...
March 23, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28332189/technical-intelligence-and-culture-nut-cracking-in-humans-and-chimpanzees
#15
Christophe Boesch, Daša Bombjaková, Adam Boyette, Amelia Meier
OBJECTIVES: According to the technical intelligence hypothesis, humans are superior to all other animal species in understanding and using tools. However, the vast majority of comparative studies between humans and chimpanzees, both proficient tool users, have not controlled for the effects of age, prior knowledge, past experience, rearing conditions, or differences in experimental procedures. We tested whether humans are superior to chimpanzees in selecting better tools, using them more dexteriously, achieving higher performance and gaining access to more resource as predicted under the technical intelligence hypothesis...
March 23, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28331604/re-establishing-the-pecking-order-niche-models-reliably-predict-suitable-habitats-for-the-reintroduction-of-red-billed-oxpeckers
#16
Riddhika Kalle, Leigh Combrink, Tharmalingam Ramesh, Colleen T Downs
Distributions of avian mutualists are affected by changes in biotic interactions and environmental conditions driven directly/indirectly by human actions. The range contraction of red-billed oxpeckers (Buphagus erythrorhynchus) in South Africa is partly a result of the widespread use of acaracides (i.e., mainly cattle dips), toxic to both ticks and oxpeckers. We predicted the habitat suitability of red-billed oxpeckers in South Africa using ensemble models to assist the ongoing reintroduction efforts and to identify new reintroduction sites for population recovery...
March 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28331251/is-focus-on-prevention-missing-in-national-health-programs-a-situation-analysis-of-iec-bcc-health-promotion-activities-in-a-district-setting-of-punjab-and-haryana
#17
Jarnail Singh Thakur, Nidhi Jaswal, Ashoo Grover
CONTEXT: Health promotion (HP) has been an integral part of all national programs although it has been a low priority in India, which has resulted in a failure to achieve the desired results. SETTINGS AND DESIGN: Situation analysis of information education communication (IEC)/behavior change communication (BCC)/HP activities within the existing national health programs was undertaken in the district of Hoshiarpur in Punjab and the district of Ambala in Haryana during 2013-14...
January 2017: Indian Journal of Community Medicine
https://www.readbyqxmd.com/read/28330510/an-integrated-environmental-improvement-of-marshlands-impact-on-control-and-elimination-of-schistosomiasis-in-marshland-regions-along-the-yangtze-river-china
#18
Le-Ping Sun, Wei Wang, Yin-Ping Zuo, Zheng-Qiu Zhang, Qing-Biao Hong, Guo-Jing Yang, Hong-Ru Zhu, You-Sheng Liang, Hai-Tao Yang
BACKGROUND: Schistosomiasis is a global snail-transmitted infectious disease of poverty. Transmission control had been achieved in China in 2015 after the control efforts for over 60 years. Currently, the remaining core regions endemic for Schistosoma japonicum are mainly located in the marshland and lake regions along the Yangtze River basin. METHODS: During the period from 2001 through 2015, an integrated environmental improvement of the marshlands was carried out through the implementation of industrial, agricultural and resources development projects in Yizheng County along the Yangtze River...
March 22, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28330491/orchestrating-differential-data-access-for-translational-research-a-pilot-implementation
#19
Marco Brandizi, Olga Melnichuk, Raffael Bild, Florian Kohlmayer, Benedicto Rodriguez-Castro, Helmut Spengler, Klaus A Kuhn, Wolfgang Kuchinke, Christian Ohmann, Timo Mustonen, Mikael Linden, Tommi Nyrönen, Ilkka Lappalainen, Alvis Brazma, Ugis Sarkans
BACKGROUND: Translational researchers need robust IT solutions to access a range of data types, varying from public data sets to pseudonymised patient information with restricted access, provided on a case by case basis. The reason for this complication is that managing access policies to sensitive human data must consider issues of data confidentiality, identifiability, extent of consent, and data usage agreements. All these ethical, social and legal aspects must be incorporated into a differential management of restricted access to sensitive data...
March 23, 2017: BMC Medical Informatics and Decision Making
https://www.readbyqxmd.com/read/28330467/mental-health-care-and-delivery-system-at-temeke-hospital-in-dar-es-salaam-tanzania
#20
Joel Seme Ambikile, Masunga K Iseselo
BACKGROUND: Low and middle income countries face many challenges in meeting mental health needs in their regions. Treatment of patients with mental disorders is inadequate in most of these countries and majority of individuals with severe mental disorders remain untreated. The bad news is that mental health problems in these countries are on the rise due to socioeconomic challenges being faced. Regardless of guidelines and directives provided by WHO for organizing mental health services, these countries continue to face many challenges in the effort to cater for mental health needs...
March 23, 2017: BMC Psychiatry
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