keyword
MENU ▼
Read by QxMD icon Read
search

Bro

keyword
https://www.readbyqxmd.com/read/28193288/accreditation-in-general-practice-in-denmark-study-protocol-for-a-cluster-randomized-controlled-trial
#1
Merethe K Andersen, Line B Pedersen, Volkert Siersma, Flemming Bro, Susanne Reventlow, Jens Søndergaard, Marius Brostrøm Kousgaard, Frans B Waldorff
BACKGROUND: Accreditation is used increasingly in health systems worldwide. However, there is a lack of evidence on the effects of accreditation, particularly in general practice. In 2016 a mandatory accreditation scheme was initiated in Denmark, and during a 3-year period all practices, as default, should undergo accreditation according to the Danish Healthcare Quality Program. The aim of this study is primarily to evaluate the effects of a mandatory accreditation scheme. METHODS/DESIGN: The study is conducted as a cluster-randomized controlled trial among 1252 practices (clusters) with 2211 general practitioners in Denmark...
February 13, 2017: Trials
https://www.readbyqxmd.com/read/28157059/danish-mmr-vaccination-coverage-is-considerably-higher-than-reported
#2
Nanna Holt, Anna Mygind, Flemming Bro
INTRODUCTION: The Danish childhood vaccination programme offers protection against measles, mumps, and rubella (MMR). Nevertheless, many children appear to be unvaccinated according to the national registers. The aim of this study was to estimate the MMR1 vaccination coverage based on a medical record review of children whose vaccination status is negative according to the register-based data. METHODS: We conducted a cross-sectional study of 19 randomly selected general practices in the Central Denmark Region including 1,712 children aged 18-42 months...
February 2017: Danish Medical Journal
https://www.readbyqxmd.com/read/28125965/microbiological-point-of-care-testing-before-antibiotic-prescribing-in-primary-care-considerable-variations-between-practices
#3
Steffen Haldrup, Reimar W Thomsen, Flemming Bro, Robert Skov, Lars Bjerrum, Mette Søgaard
BACKGROUND: Point-of-care testing (POCT) in primary care may improve rational antibiotic prescribing. We examined use of POCT in Denmark, including patient- and general practitioner (GP)-related predictors. METHODS: We linked nationwide health care databases to assess POCT use (C-reactive protein (CRP), group A streptococcal (GAS) antigen swabs, bacteriological cultures, and urine test strips) per 1,000 overall GP consultations, 2004-2013. We computed odds ratios (OR) of POCT in patients prescribed antibiotics according to patient and GP age and sex, GP practice type, location, and workload...
January 26, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28122273/competence-evaluation-processes-for-nursing-students-abroad-findings-from-an-international-case-study
#4
Cristina Tommasini, Beata Dobrowolska, Danuta Zarzycka, Claudia Bacatum, Anne Marie Gran Bruun, Dag Korsath, Siv Roel, Mette Bro Jansen, Tine Milling, Anne Deschamps, Stefanos Mantzoukas, Christine Mantzouka, Alvisa Palese
BACKGROUND: Assessing clinical competence in nursing students abroad is a challenge, and requires both methods and instruments capable of capturing the multidimensional nature of the clinical competences acquired. OBJECTIVES: The aim of the study was to compare the clinical competence assessment processes and instruments adopted for nursing students during their clinical placement abroad. DESIGN: A case study design was adopted in 2015. SETTING AND PARTICIPANTS: A purposeful sample of eight nursing programmes located in seven countries (Belgium, Denmark, Greece, Norway, Poland, Portugal and Italy) were approached...
January 10, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28099439/single-versus-serial-measurements-of-neuron-specific-enolase-and-prediction-of-poor-neurological-outcome-in-persistently-unconscious-patients-after-out-of-hospital-cardiac-arrest-a-ttm-trial-substudy
#5
Sebastian Wiberg, Christian Hassager, Pascal Stammet, Matilde Winther-Jensen, Jakob Hartvig Thomsen, David Erlinge, Michael Wanscher, Niklas Nielsen, Tommaso Pellis, Anders Åneman, Hans Friberg, Jan Hovdenes, Janneke Horn, Jørn Wetterslev, John Bro-Jeppesen, Matthew P Wise, Michael Kuiper, Tobias Cronberg, Yvan Gasche, Yvan Devaux, Jesper Kjaergaard
BACKGROUND: Prediction of neurological outcome is a crucial part of post cardiac arrest care and prediction in patients remaining unconscious and/or sedated after rewarming from targeted temperature management (TTM) remains difficult. Current guidelines suggest the use of serial measurements of the biomarker neuron-specific enolase (NSE) in combination with other predictors of outcome in patients admitted after out-of-hospital cardiac arrest (OHCA). This study sought to investigate the ability of NSE to predict poor outcome in patients remaining unconscious at day three after OHCA...
2017: PloS One
https://www.readbyqxmd.com/read/28095314/cloning-and-expression-characterization-of-peroxisome-proliferator-activated-receptors-ppars-with-their-agonists-dietary-lipids-and-ambient-salinity-in-rabbitfish-siganus-canaliculatus
#6
Cuihong You, Danli Jiang, Qinghao Zhang, Dizhi Xie, Shuqi Wang, Yewei Dong, Yuanyou Li
Rabbitfish Siganus canaliculatus is the first marine teleost reported to have the ability of biosynthesizing C20-22 long-chain polyunsaturated fatty acids (LC-PUFA) from C18 precursors, and thus provides a model for studying the regulatory mechanisms of LC-PUFA biosynthesis in teleosts. To investigate the possible roles of peroxisome proliferator-activated receptors (PPARs), critical transcription factors involved in the regulation of lipid metabolism, in the regulation of LC-PUFA biosynthesis in rabbitfish, the PPAR genes were cloned and their expression characterization with PPAR agonists, dietary lipid resource, and ambient salinity were examined...
January 14, 2017: Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology
https://www.readbyqxmd.com/read/28095147/management-of-small-renal-masses-american-society-of-clinical-oncology-clinical-practice-guideline
#7
Antonio Finelli, Nofisat Ismaila, Bill Bro, Jeremy Durack, Scott Eggener, Andrew Evans, Inderbir Gill, David Graham, William Huang, Michael A S Jewett, Sheron Latcha, William Lowrance, Mitchell Rosner, Bobby Shayegan, R Houston Thompson, Robert Uzzo, Paul Russo
Purpose To provide recommendations for the management options for patients with small renal masses (SRMs). Methods By using a literature search and prospectively defined study selection, we sought systematic reviews, meta-analyses, randomized clinical trials, prospective comparative observational studies, and retrospective studies published from 2000 through 2015. Outcomes included recurrence-free survival, disease-specific survival, and overall survival. Results Eighty-three studies, including 20 systematic reviews and 63 primary studies, met the eligibility criteria and form the evidentiary basis for the guideline recommendations...
February 20, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28058732/bromocriptine-treatment-at-the-end-of-lactation-prevents-hyperphagia-higher-visceral-fat-and-liver-triglycerides-in-early-weaned-rats-at-adulthood
#8
Nayara Peixoto-Silva, Egberto G Moura, Janaine C Carvalho, Jéssica L Nobre, Fernanda T Quitete, Cintia R Pinheiro, Ana Paula Santos-Silva, Elaine de Oliveira, Patricia C Lisboa
Non-pharmacological early weaning (NPEW) leads offspring to obesity, higher liver oxidative stress and microsteatosis in adulthood. Pharmacological EW (PEW) by maternal treatment with bromocriptine (BRO) causes obesity in the adult progeny but precludes hepatic injury. To test the hypothesis that BRO prevents the deleterious changes of NPEW, we injected BRO into the pups from the NPEW model on late lactation. Lactating rats were divided into 2 groups: dams with an adhesive bandage around the body to prevent breastfeeding on the last 3 days of lactation and dams whose pups had free suckling (C)...
January 6, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28057435/antimicrobial-susceptibility-to-%C3%AE-lactam-antibiotics-and-production-of-bro-%C3%AE-lactamase-in-clinical-isolates-of-moraxella-catarrhalis-from-a-japanese-hospital
#9
Kageto Yamada, Katsumi Arai, Ryoichi Saito
We investigated BRO-β-lactamase production of Moraxella catarrhalis isolates and its antimicrobial susceptibility to β-lactams. Of the 233 isolates, 232 were BRO producers and 224 were BRO-1 producers. Four isolates exhibited elevated ceftriaxone minimum inhibitory concentration (2 μg/mL) and different pulsed-field gel electrophoresis patterns and we expect this number to increase in the near future.
December 18, 2016: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28049321/communication-interaction-of-bro-radical-with-the-surface-of-water
#10
Chongqin Zhu, Yurui Gao, Jie Zhong, Yingying Huang, Joseph S Francisco, Xiao Cheng Zeng
Solvation of a BrO radical in a slab of water is investigated using adaptive buffered force quantum mechanics/molecular mechanics (QM/MM) dynamics simulations. The simulation results show that the BrO radical exhibits preference towards the water surface with respect to the interior region of the water slab, despite BrO's high affinity to water. Another important finding is the weakening of (BrO)Br⋯O(water) interaction at the water surface due to competitive interactions between (BrO)Br⋯O(water) and (water)H⋯O(water)...
December 28, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28042073/predictors-of-complicated-grief-and-depression-in-bereaved-caregivers-a-nationwide-prospective-cohort-study
#11
Mette Kjaergaard Nielsen, Mette Asbjoern Neergaard, Anders Bonde Jensen, Peter Vedsted, Flemming Bro, Mai-Britt Guldin
CONTEXT: Complicated grief and depressive symptoms in bereaved caregivers have been associated with female gender, spousal relation, and preloss psychological distress, but population-based, prospective studies are scarce. OBJECTIVES: We aimed to investigate whether severe preloss grief and depressive symptoms, caregiver burden, preparedness for death, communication about dying, and socioeconomic factors predicted complicated grief and postloss depressive symptoms...
December 29, 2016: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28028702/field-evidence-of-bird-poisonings-by-imidacloprid-treated-seeds-a-review-of-incidents-reported-by-the-french-sagir-network-from-1995-to-2014
#12
Florian Millot, Anouk Decors, Olivier Mastain, Thomas Quintaine, Philippe Berny, Danièle Vey, Romain Lasseur, Elisabeth Bro
The large-scale use of neonicotinoid insecticides has raised growing concerns about their potential adverse effects on farmland birds, and more generally on biodiversity. Imidacloprid, the first neonicotinoid commercialized, has been identified as posing a risk for seed-eating birds when it is used as seed treatment of some crops since the consumption of a few dressed seeds could cause mortality. But evidence of direct effects in the field is lacking. Here, we reviewed the 103 wildlife mortality incidents reported by the French SAGIR Network from 1995 to 2014, for which toxicological analyses detected imidacloprid residues...
December 27, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28005927/antiproliferative-and-pro-apoptotic-effects-of-mir-4286-inhibition-in-melanoma-cells
#13
Anna Komina, Nadezhda Palkina, Mariya Aksenenko, Seseg Tsyrenzhapova, Tatiana Ruksha
INTRODUCTION: MicroRNAs are essential regulators of gene expression at the post-transcriptional level. Their expression is altered in cancer tissues, and evaluation of these alterations is considered a promising tool used to diagnose and identify prognostic markers. MATERIALS AND METHODS: The microRNA expression profiles of formalin-fixed, paraffin-embedded melanoma and melanocytic nevi samples were estimated with a microarray and subsequently validated by real-time PCR...
2016: PloS One
https://www.readbyqxmd.com/read/27981451/bromelain-functionalized-multiple-wall-lipid-core-nanocapsules-formulation-chemical-structure-and-antiproliferative-effect-against-human-breast-cancer-cells-mcf-7
#14
Catiúscia P Oliveira, Willian A Prado, Vladimir Lavayen, Sabrina L Büttenbender, Aline Beckenkamp, Bruna S Martins, Diogo S Lüdtke, Leandra F Campo, Fabiano S Rodembusch, Andréia Buffon, Adalberto Pessoa, Silvia S Guterres, Adriana R Pohlmann
PURPOSE: This study was conducted a promising approach to surface functionalization developed for lipid-core nanocapsules and the merit to pursue new strategies to treat solid tumors. METHODS: Bromelain-functionalized multiple-wall lipid-core nanocapsules (Bro-MLNC-Zn) were produced by self-assembling following three steps of interfacial reactions. Physicochemical and structural characteristics, in vitro proteolytic activity (casein substrate) and antiproliferative activity (breast cancer cells, MCF-7) were determined...
December 15, 2016: Pharmaceutical Research
https://www.readbyqxmd.com/read/27965172/molecular-weight-specific-impact-of-soluble-and-immobilized-hyaluronan-on-cd44-expressing-melanoma-cells-in-3d-collagen-matrices
#15
Jiranuwat Sapudom, Franziska Ullm, Steve Martin, Liv Kalbitzer, Johanna Naab, Stephanie Möller, Matthias Schnabelrauch, Ulf Anderegg, Stephan Schmidt, Tilo Pompe
: Hyaluronan (HA) and its principal receptor CD44 are known to be involved in regulating tumor cell dissemination and metastasis. The direct correlation of CD44-HA interaction on proliferation and invasion of tumor cells in dependence on the molecular weight and the presentation form of HA is not fully understood because of lack of appropriate matrix models. To address this issue, we reconstituted 3D collagen (Coll I) matrices and functionalized them with HA of molecular weight of 30-50kDa (low molecular weight; LMW-HA) and 500-750kDa (high molecular weight; HMW-HA)...
December 10, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/27923428/association-of-restless-legs-syndrome-with-incident-parkinson-disease
#16
Della Bro, Ruth O'Hara, Michelle Primeau, Andrea Hanson-Kahn, Joachim Hallmayer, Jonathan A Bernstein
STUDY OBJECTIVES: The association between restless legs syndrome (RLS) and Parkinson's Disease (PD) has been extensively studied with inconclusive results, therefore we prospectively examined the associations of the presence of RLS with development of incident PD. METHODS: From a nationally representative prospective cohort of almost 3.5 million US veterans (age: 60±14 years, 93% male, median follow-up time of 7.8 years (IQR: 6.4-8.4 years)), we created a propensity-matched cohort of 100,882 PD-free patients and examined the association between prevalent RLS and incident PD...
November 28, 2016: Sleep
https://www.readbyqxmd.com/read/27923425/sleep-disturbances-in-individuals-with-phelan-mcdermid-syndrome-correlation-with-caregivers-sleep-quality-and-daytime-functioning
#17
Della Bro, Ruth O'Hara, Michelle Primeau, Andrea Hanson-Kahn, Joachim Hallmayer, Jonathan A Bernstein
STUDY OBJECTIVES: The aims of this study were: to document sleep disturbances in individuals with Phelan-McDermid syndrome, to assess whether these individuals had been evaluated for sleep disorders, and to examine relationships between the sleep behavior of these individuals and the sleep behavior and daytime functioning of their caregivers. METHODS: Participants were 193 caregivers of individuals with Phelan-McDermid Syndrome recruited by the Phelan-McDermid Syndrome Foundation...
November 28, 2016: Sleep
https://www.readbyqxmd.com/read/27906398/cooperation-and-competition-between-halogen-bonding-and-van-der-waals-forces-in-supramolecular-engineering-at-the-aliphatic-hydrocarbon-graphite-interface-position-and-number-of-bromine-group-effects
#18
Bao Zha, Meiqiu Dong, Xinrui Miao, Shan Peng, Yican Wu, Kai Miao, Yi Hu, Wenli Deng
Herein, the photophysical properties of two π-conjugated thienophenanthrene derivatives (6,9- and 5,10-DBTD) are reported. Their self-assembled monolayers in aliphatic hydrocarbon solvents under different concentrations were investigated by scanning tunneling microscopy on a graphite surface. The STM results revealed that the self-assembled structures of the two geometrical isomers exhibited absolutely different behaviors. At the aliphatic solvent/graphite interface, 6,9-DBTD produced almost a single stable coassembled linear structure, except for that with n-tridecane as the solvent...
January 7, 2017: Nanoscale
https://www.readbyqxmd.com/read/27891227/society-for-immunotherapy-of-cancer-consensus-statement-on-immunotherapy-for-the-treatment-of-renal-cell-carcinoma
#19
Brian I Rini, David F McDermott, Hans Hammers, William Bro, Ronald M Bukowski, Bernard Faba, Jo Faba, Robert A Figlin, Thomas Hutson, Eric Jonasch, Richard W Joseph, Bradley C Leibovich, Thomas Olencki, Allan J Pantuck, David I Quinn, Virginia Seery, Martin H Voss, Christopher G Wood, Laura S Wood, Michael B Atkins
Immunotherapy has produced durable clinical benefit in patients with metastatic renal cell cancer (RCC). In the past, patients treated with interferon-alpha (IFN) and interleukin-2 (IL-2) have achieved complete responses, many of which have lasted for multiple decades. More recently, a large number of new agents have been approved for RCC, several of which attack tumor angiogenesis by inhibiting vascular endothelial growth factors (VEGF) and VEGF receptors (VEGFR), as well as tumor metabolism, inhibiting the mammalian target of rapamycin (mTOR)...
2016: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/27822123/development-of-an-algorithm-to-identify-urgent-referrals-for-suspected-cancer-from-the-danish-primary-care-referral-database
#20
Berit Skjødeberg Toftegaard, Louise Mahncke Guldbrandt, Kaare Rud Flarup, Hanne Beyer, Flemming Bro, Peter Vedsted
BACKGROUND: Accurate identification of specific patient populations is a crucial tool in health care. A prerequisite for exploring the actions taken by general practitioners (GPs) on symptoms of cancer is being able to identify patients urgently referred for suspected cancer. Such system is not available in Denmark; however, all referrals are electronically stored. This study aimed to develop and test an algorithm based on referral text to identify urgent cancer referrals from general practice...
2016: Clinical Epidemiology
keyword
keyword
67696
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"