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https://www.readbyqxmd.com/read/29857683/periodic-changes-in-the-oxidation-states-of-the-center-ion-in-the-cobalt-histidine-complex-induced-by-the-bro-3-so-3-2-ph-oscillator
#1
Krisztina Kurin-Csörgei, Eszter Poros, Julianna Csepiova, Miklós Orbán
The coupling of acid-base type pH-dependent equilibria to pH-oscillators expanded significantly the number and type of species which can participate in oscillatory chemical processes. Here, we report a new version of oscillatory phenomena that can appear in coupled oscillators. Oscillations in the oxidation states of the center ion bound in a chelate complex were generated in a combined system, when the participants of the oscillator as dynamical unit and the components of the complex formation interacted with each other through redox reaction...
May 2018: Chaos
https://www.readbyqxmd.com/read/29851219/bromination-improves-tetraazapentacene%C3%A2-s-electron-mobilities
#2
Hilmar Reiss, Lei Ji, Jie Han, Silke Koser, Olena Tverskoy, Jan Freudenberg, Michael Moos, Alexandra Friedrich, Ivo Krummenacher, Christoph Lambert, Holger Braunschweig, Andreas Dreuw, Todd B Marder, Uwe Heiko Bunz
A cyclocondensation-based preparation of tetra¬bro¬mo¬tetra-azapentacene (BrTAP) is described using TIPS-ethynyl-substi-tuted diaminoarenes with in-situ obtained 4,5-dibromocyclohexa-3,5-diene-1,2-dione. BrTAP is easily reduced to its air stable radical anion; elec¬tron mobilities > 0.56 cm2 V 1 s 1 are achieved in thin film transistors.
May 31, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29848295/who-needs-collaborative-care-treatment-a-qualitative-study-exploring-attitudes-towards-and-experiences-with-mental-healthcare-among-general-practitioners-and-care-managers
#3
Marlene Christina Rosengaard Møller, Anna Mygind, Flemming Bro
BACKGROUND: Collaborative care treatment is widely recognized as an effective approach to improve the quality of mental healthcare through enhanced and structured collaboration between general practice and specialized psychiatry. However, studies indicate that the complexity of collaborative care treatment interventions challenge the implementation in real-life general practice settings. Four Danish Collaborative Care Models were launched in 2014 for patients with mild/moderate anxiety and depression...
May 30, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29799497/theoretical-investigations-on-mechanisms-and-pathways-of-c%C3%A2-h%C3%A2-o%C3%A2-with-bro-reaction-in-the-atmosphere
#4
Chenggang Lu, Yizhen Tang, Wei Zhang, Xunshuai Qu, Zhihao Fu
In this work, feasible mechanisms and pathways of the C₂H₅O₂ + BrO reaction in the atmosphere were investigated using quantum chemistry methods, i.e., QCISD(T)/6-311++G(2df,2p)//B3LYP/6-311++G(2df,2p) levels of theory. Our result indicates that the title reaction occurs on both the singlet and triplet potential energy surfaces (PESs). Kinetically, singlet C₂H₅O₃Br and C₂H₅O₂BrO were dominant products under the atmospheric conditions below 300 K. CH₃CHO₂ + HOBr, CH₃CHO + HOBrO, and CH₃CHO + HBrO₂ are feasible to a certain extent thermodynamically...
May 25, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29785217/expression-of-phi11-gp07-causes-filamentation-in-escherichia-coli
#5
Avijit Das, Sumit Biswas, Malabika Biswas
Background: The Gp07 protein of aureophage Phi11 exhibits growth inhibitory effects when overexpressed in E. coli .The protein harbors two domains- an amino terminal Bro-like domain and a carboxy terminal Ant superfamily like KilA domain, of which the KilA domain retains the growth inhibitory effect of Gp07. Methods: We studied the effects exerted by the overexpression of Gp07 and its separate domains upon the growth rate as well as the morphology of the E. coli cells...
2018: Open Microbiology Journal
https://www.readbyqxmd.com/read/29770502/psychosocial-risk-screening-of-expectant-fathers-in-an-urban-home-visiting-service-population
#6
Richard E Carlson, Mageen C Caines, Patricia A Harrison
OBJECTIVE: To examine the occurrence of psychosocial risk factors among expectant fathers whose female partners were enrolled in prenatal home visiting services. DESIGN: Cross-sectional, exploratory, quantitative design. SAMPLE: Expectant father-mother pairs were recruited from two urban home visiting programs to participate in a randomized controlled trial of a father advocate intervention. The study sample consisted of 66 father-mother pairs who completed structured interviews at baseline, before randomization...
May 17, 2018: Public Health Nursing
https://www.readbyqxmd.com/read/29762267/the-more-the-better-the-usefulness-of-brimonidine-as-the-fourth-anti-glaucoma-eye-drop
#7
Tomas Bro, Christina Lindén
PURPOSE: To study the intraocular pressure (IOP)-lowering effect of adding brimonidine as the fourth anti-glaucoma medication to a pre-existing therapy of three topical drugs. METHODS: A retrospective, register-based, cohort study of medical records and computerized medical information comprising one county in Sweden. The main outcome measure was change in IOP after brimonidine addition. Short- and long-term effects were evaluated. RESULTS: Out of 4910 patients on anti-glaucoma medication, 69 (1...
May 12, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29759216/geometric-search-a-new-approach-for-fitting-parafac2-models-on-gc-ms-data
#8
Kuangda Tian, Lijun Wu, Shungeng Min, Rasmus Bro
PARAFAC2 is a powerful decomposition method which is ideally suited for modeling gas chromatography-mass spectrometry (GC-MS) data. However, the most widely used fitting algorithms (alternating least squares, ALS) are very slow which hinders use of the model. In this paper, an iterative method called geometric search is proposed to fit the PARAFAC2 model. This method models the PARAFAC2 loading parameters as geometric sequences with offsets during the ALS iterations. It extrapolates the optimal parameters from prior iterations to accelerate ALS convergence process...
August 1, 2018: Talanta
https://www.readbyqxmd.com/read/29741070/-isotope-analysis-of-ammonium-and-nitrate-a-review-on-measured-methods-and-their-application
#9
Dong Wei Liu, Ying Tu, Yun Ting Fang
In the past several decades, a variety of methods have been developed for measuring the isotopic composition of ammonium (δ15 N) and nitrate (δ15 N and δ18 O). This review summarized the advantages and disadvantages of these methods. Nowadays, the most popular method for measu-ring δ15 N of ammonium is the combined hypobromite (BrO- ) and hydroxylamine (NH2 OH) me-thod, while for δ15 N and δ18 O of nitrate is the denitrifier method and the sodium azide (NaN3 ) me-thod. These methods convert NH4 + or NO3 - into nitrous oxide (N2 O) and measure its isotopic compositions, with higher analytical precision because of the lower background concentration of atmospheric N2 O...
July 18, 2017: Ying Yong Sheng Tai Xue Bao, the Journal of Applied Ecology
https://www.readbyqxmd.com/read/29698781/in-vivo-and-in-vitro-investigation-of-anti-inflammatory-and-mucus-regulatory-activities-of-a-fixed-combination-of-thyme-and-primula-extracts
#10
Jan Seibel, Kirill Kryshen, Judit E Pongrácz, Martin D Lehner
Hypersecretion of viscous mucus is one of the hallmark symptoms of acute and chronic bronchitis and typically develops secondary to an inflammation of the airway epithelium. Bronchipret® TP film-coated tablets (BRO), an herbal medicinal product containing a fixed combination of thyme herb and primula root extracts, has been successfully used clinically for the treatment of acute bronchitis for more than two decades. However, the underlying pharmacological mechanisms of action have not been fully understood so far...
April 23, 2018: Pulmonary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29573825/inorganic-fouling-mitigation-by-salinity-cycling-in-batch-reverse-osmosis
#11
David M Warsinger, Emily W Tow, Laith A Maswadeh, Grace B Connors, Jaichander Swaminathan, John H Lienhard V
Enhanced fouling resistance has been observed in recent variants of reverse osmosis (RO) desalination which use time-varying batch or semi-batch processes, such as closed-circuit RO (CCRO) and pulse flow RO (PFRO). However, the mechanisms of batch processes' fouling resistance are not well-understood, and models have not been developed for prediction of their fouling performance. Here, a framework for predicting reverse osmosis fouling is developed by comparing the fluid residence time in batch and continuous (conventional) reverse osmosis systems to the nucleation induction times for crystallization of sparingly soluble salts...
June 15, 2018: Water Research
https://www.readbyqxmd.com/read/29571652/the-complete-genome-sequence-of-the-first-hesperiid-infecting-alphabaculovirus-isolated-from-the-leguminous-pest-urbanus-proteus-lepidoptera-hesperiidae
#12
Ethiane R Santos, Lucas B Oliveira, Lenen Peterson, Daniel R Sosa-Gómez, Bergmann Morais Ribeiro, Daniel M P Ardisson-Araújo
Baculoviruses are insect viruses largely used as expression vectors and biopesticides. These viruses can efficiently infect the larval stage of several agricultural pests worldwide causing a lethal disease. In this work, we found a novel baculovirus isolated from the larval stage of Urbanus proteus (L.), the bean leafroller and characterized its complete genome. This is an important pest of several leguminous plants in Brazil and belongs to the butterfly family Hesperiidae, from where no baculovirus genome sequence has been described...
April 2, 2018: Virus Research
https://www.readbyqxmd.com/read/29553891/importance-of-comorbidities-in-comatose-survivors-of-shockable-and-non-shockable-out-of-hospital-cardiac-arrest-treated-with-target-temperature-management
#13
Idrees Salam, Jakob Hartvig Thomsen, Jesper Kjaergaard, John Bro-Jeppesen, Martin Frydland, Matilde Winther-Jensen, Lars Køber, Michael Wanscher, Christian Hassager, Helle Søholm
OBJECTIVE: Comorbidity prior to out-of-hospital cardiac arrest (OHCA) and primary rhythm in relation to survival is not well established. We aimed to assess the prognostic importance of comorbidity in relation to primary rhythm in OHCA-patients treated with Target Temperature Management (TTM). DESIGN: Consecutive comatose survivors of OHCA treated with TTM in hospitals in the Copenhagen area between 2002-2011 were included. Utstein-based pre- and in-hospital data collection was performed...
June 2018: Scandinavian Cardiovascular Journal: SCJ
https://www.readbyqxmd.com/read/29547534/a-novel-betabaculovirus-isolated-from-the-monocot-pest-mocis-latipes-lepidoptera-noctuidae-and-the-evolution-of-multiple-copy-genes
#14
Daniel M P Ardisson-Araújo, Ana Maria Rodrigues da Silva, Fernando L Melo, Ethiane Rozo Dos Santos, Daniel R Sosa-Gómez, Bergmann M Ribeiro
In this report, we described the genome of a novel baculovirus isolated from the monocot insect pest Mocis latipes , the striped grass looper. The genome has 134,272 bp in length with a G + C content of 38.3%. Based on the concatenated sequence of the 38 baculovirus core genes, we found that the virus is a betabaculovirus closely related to the noctuid-infecting betabaculoviruses including Pseudaletia unipuncta granulovirus (PsunGV), Trichoplusia ni granulovirus (TnGV), Helicoverpa armigera granulovirus (HearGV), and Xestia c-nigrum granulovirus (XecnGV)...
March 16, 2018: Viruses
https://www.readbyqxmd.com/read/29462643/pirouetting-pigs-a-large-non-primate-animal-model-based-on-unilateral-6-hydroxydopamine-lesioning-of-the-nigrostriatal-pathway
#15
Anette Bro Christensen, Jens Christian Hedemann Sørensen, Kåre Schmidt Ettrup, Dariusz Orlowski, Carsten Reidies Bjarkam
INTRODUCTION: The rotating 6-hydroxydopamine (6-OHDA) rat model has long been important when developing new treatment strategies for Parkinson's disease (PD). Similar non-human primate models have been developed for translational research purposes as large animal models are required by regulatory bodies as an intermediate "phase 0" trial step. However, experimental research in non-human primates encounters several economical and regulatory issues, which may be avoided by the alternative use of pigs as a large animal model for experimental brain research...
February 17, 2018: Brain Research Bulletin
https://www.readbyqxmd.com/read/29454309/perceptions-about-screening-for-prostate-cancer-using-genetic-lifetime-risk-assessment-a-qualitative-study
#16
Pia Kirkegaard, Adrian Edwards, Trine Laura Overgaard Nielsen, Torben Falck Ørntoft, Karina Dalsgaard Sørensen, Michael Borre, Flemming Bro
BACKGROUND: Most health authorities do not recommend screening for prostate cancer with PSA tests in asymptomatic patients who are not at increased risk. However, opportunistic screening for prostate cancer is still wanted by many patients and it is widely used in primary care clinics, with potential for overdiagnosis and overtreatment. Better tools for risk assessment have been called for, to better target such opportunistic screening. Our aim was to explore perceptions about prostate cancer risk and subsequent opportunistic screening among patients who were not at increased risk of prostate cancer after a first PSA test plus a genetic lifetime risk assessment...
February 17, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29429425/association-between-alcohol-and-substance-use-disorders-and-psychiatric-service-use-in-patients-with-severe-mental-illness-a-nationwide-danish-register-based-cohort-study
#17
Kirstine Bro Jørgensen, Merete Nordentoft, Carsten Hjorthøj
BACKGROUND: Substance use disorder is highly prevalent in people with psychiatric disorders, and known to impede the psychiatric treatment. Some studies show increased rates of service use, while others show a decrease. These conflicting results are further hampered by a lack of large-scale studies. The aim of this study was to investigate the association between substance use disorder and psychiatric service use in psychiatric patients. METHODS: The study was a prospective registry-based cohort study including patients with severe mental illness...
February 12, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29409741/lipoic-acid-metabolism-in-trypanosoma-cruzi-as-putative-target-for-chemotherapy
#18
Paola Vacchina, Daniel A Lambruschi, Antonio D Uttaro
Lipoic acid (LA) is a cofactor of relevant enzymatic complexes including the glycine cleave system and 2-ketoacid dehydrogenases. Intervention on LA de novo synthesis or salvage could have pleiotropic deleterious effect in cells, making both pathways attractive for chemotherapy. We show that Trypanosoma cruzi was susceptible to treatment with LA analogues. 8-Bromo-octanic acid (BrO) inhibited the growth of epimastigote forms of both Dm28c and CL Brener strains, although only at high (chemotherapeutically irrelevant) concentrations...
March 2018: Experimental Parasitology
https://www.readbyqxmd.com/read/29368822/slutreplik-g%C3%A3-llande-v%C3%A3-t-amd-%C3%A2-men-hur-ska-vi-g%C3%A3-ra-med-avastin
#19
Tomas Bro
No abstract text is available yet for this article.
December 27, 2017: Läkartidningen
https://www.readbyqxmd.com/read/29326145/return-to-work-and-participation-in-society-after-out-of-hospital-cardiac-arrest
#20
Gisela Lilja, Niklas Nielsen, John Bro-Jeppesen, Hannah Dunford, Hans Friberg, Caisa Hofgren, Janneke Horn, Angelo Insorsi, Jesper Kjaergaard, Fredrik Nilsson, Paolo Pelosi, Tineke Winters, Matt P Wise, Tobias Cronberg
BACKGROUND: The aim of this study was to describe out-of-hospital cardiac arrest (OHCA) survivors' ability to participate in activities of everyday life and society, including return to work. The specific aim was to evaluate potential effects of cognitive impairment. METHODS AND RESULTS: Two hundred eighty-seven OHCA survivors included in the TTM trial (Target Temperature Management) and 119 matched control patients with ST-segment-elevation myocardial infarction participated in a follow-up 180 days post-event that included assessments of participation, return to work, emotional problems, and cognitive impairment...
January 2018: Circulation. Cardiovascular Quality and Outcomes
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