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https://www.readbyqxmd.com/read/29206499/expert-judgment-based-multicriteria-decision-models-to-assess-the-risk-of-pesticides-on-reproduction-failures-of-grey-partridge
#1
J Devillers, H Devillers, E Bro, F Millot
A suite of models is proposed for estimating the risk of pesticides against the grey partridge (Perdix perdix) and their clutches. Radio-tracked data of females, description and location of the clutches, and data on the pesticide treatments during the laying periods of the partridges were used as basic information. Quantitative structure-activity relationship (QSAR) and quantitative structure-property relationship (QSPR) modelling allowed us to characterize the pesticides by their 1-octanol/water partition coefficient (log P), vapour pressure, primary and ultimate biodegradation potential, acute toxicity (LD50) on P...
November 2017: SAR and QSAR in Environmental Research
https://www.readbyqxmd.com/read/29153667/preeclampsia-and-later-cardiovascular-disease-what-do-national-guidelines-recommend
#2
Gitte Bro Schmidt, Martin Christensen, Ulla Breth Knudsen
Preeclamptic women have an increased risk of hypertension and cardiovascular disease (CVD) later in life. The aim was to compare the latest clinical recommendations on post-preeclamptic prevention of hypertension and CVD published by eight National Associations of Gynecologists and Obstetricians. Definitions of preeclampsia differ internationally. Recommendations on when, how and who to screen to reduce post-preeclamptic CVD risk also show substantial variation. The diverging preeclampsia definitions make CVD prevention strategies difficult to compare...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29126001/a-robust-heteronuclear-dipolar-recoupling-method-comparable-to-tedor-for-proteins-in-magic-angle-spinning-solid-state-nmr
#3
Zhengfeng Zhang, Jianping Li, Yanke Chen, Huayong Xie, Jun Yang
In this letter, we propose a robust heteronuclear dipolar recoupling method for proteins in magic-angle spinning (MAS) solid-state NMR. This method is as simple, robust and efficient as the well-known TEDOR in the aspect of magnetization transfer between (15)N and (13)C. Deriving from our recent band-selective dual back-to-back pulses (DBP) (Zhang et al., 2016), this method uses new phase-cycling schemes to realize broadband DBP (Bro-DBP). For broadband (15)N-(13)C magnetization transfer (simultaneous (15)N→(13)C' and (15)N→(13)Cα), Bro-DBP has almost the same (15)N→(13)Cα efficiency while offers 30-40% enhancement on (15)N→(13)C' transfer, compared to TEDOR...
October 31, 2017: Journal of Magnetic Resonance
https://www.readbyqxmd.com/read/29121265/decisions-at-the-end-of-life-the-inimitable-hallmark-of-the-lawyer
#4
Mary Donnelly
THIS case commentary analyses the application of the best interests standard in section 4 of the Mental Capacity Act 2005 by the Court in the decision in Abertawe Bro Morgannwg University Local Health Board v RY (by his litigation friend the official solicitor) and CP [2017] EWCOP 2. It evaluates the way in which the law impacted on how clinical decisions in respect of RY were made and identifies systemic concerns arising from the case.
November 7, 2017: Medical Law Review
https://www.readbyqxmd.com/read/29112383/ozone-formation-induced-by-the-impact-of-reactive-bromine-and-iodine-species-on-photochemistry-in-a-polluted-marine-environment
#5
Moshe Shechner, Eran Tas
Reactive iodine and bromine species (RIS and RBS, respectively) are known for altering atmospheric chemistry, causing sharp tropospheric ozone (O3) depletion in polar regions and significant O3 reduction in the marine boundary layer (MBL). Here we use measurement-based modelling to show that, unexpectedly, both RIS and RBS can lead to enhanced O3 formation in a polluted marine environment under volatile organic compound (VOC)-limited conditions associated with high nitrogen oxide (NOX = [NO] + [NO2]) concentrations...
November 7, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29079537/enzyme-decorated-drug-carriers-targeted-swords-to-cleave-and-overcome-the-mucus-barrier
#6
Claudia Menzel, Andreas Bernkop-Schnürch
The use of mucus permeating drug carrier systems being able to overcome the mucus barrier can lead to a remarkable enhancement in bioavailability. One promising approach is the design of mucolytic enzyme decorated carrier systems (MECS). These systems include micro- and nanoparticles as well as self-emulsifying drug delivery systems (SEDDS) decorated with mucin cleaving enzymes such as papain (PAP) or bromelain (BRO). MECS are able to cross the mucus barrier in a comparatively efficient manner by cleaving mucus substructures in front of them on their way to the epithelium...
October 24, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/29064270/women-have-a-worse-prognosis-and-undergo-fewer-coronary-angiographies-after-out-of-hospital-cardiac-arrest-than-men
#7
Matilde Winther-Jensen, Christian Hassager, Jesper Kjaergaard, John Bro-Jeppesen, Jakob H Thomsen, Freddy K Lippert, Lars Køber, Michael Wanscher, Helle Søholm
BACKGROUND: Out-of-hospital cardiac arrest is more often reported in men than in women. OBJECTIVES: We aimed to assess sex-related differences in post-resuscitation care; especially with regards to coronary angiography, percutaneous coronary intervention, mortality and functional status after out-of-hospital cardiac arrest. METHODS: We included 704 consecutive adult out-of-hospital cardiac arrest-patients with cardiac aetiology in the Copenhagen area from 2007-2011...
February 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28994291/potential-energy-curves-transition-dipole-moments-and-franck-condon-factors-of-the-12-low-lying-states-of-bro-anion
#8
Yuan Yin, Deheng Shi, Jinfeng Sun, Zunlue Zhu
This work investigates the spectroscopic parameters, vibrational levels, and transition probabilities of 12 low-lying states, which are generated from the first dissociation limit, Br((2)Pu) + O(-)((2)Pu), of the BrO(-) anion. The 12 states are X(1)Σ(+), 2(1)Σ(+), 1(1)Σ(-), 1(1)Π, 2(1)Π, 1(1)Δ, a(3)Π, 1(3)Σ(+), 2(3)Σ(+), 1(3)Σ(-), 2(3)Π, and 1(3)Δ. The potential energy curves are calculated with the complete active-space self-consistent field method, which is followed by the internally contracted multireference configuration interaction approach with Davidson modification...
October 18, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28990837/quercetin-nanoparticles-alter-pharmacokinetics-of-bromocriptine-reflecting-its-enhanced-inhibitory-action-on-liver-and-intestinal-cyp-3a-enzymes-in-rats
#9
Suresh Palle, Prasad Neerati
1. Quercetin is a dietary flavonoid has extremely low water solubility and found to possess CYP3A inhibitory activity. The purpose of the present study was to evaluate the effect of quercetin and quercetin nanoparticles (NQC) on the pharmacokinetics of bromocriptine (BRO) in rats. 2. NQC prepared by antisolvent precipitation method and characterized by SEM and dissolution test. The following methods were used in this study i.e. in vitro liver and intestinal CYP3A microsomal activity and in vitro non-everted sac method...
October 9, 2017: Xenobiotica; the Fate of Foreign Compounds in Biological Systems
https://www.readbyqxmd.com/read/28988472/quantitative-determination-of-bulk-molecular-concentrations-of-%C3%AE-agonists-in-pork-tissue-samples-by-direct-internal-extractive-electrospray-ionization-mass-spectrometry
#10
Jiaquan Xu, Shengrui Xu, Yipo Xiao, Konstantin Chingin, Haiyan Lu, Runhan Yan, Huanwen Chen
Rapid quantitative determination of bulk molecular concentration in solid samples without sample pretreatment is demonstrated using the internal extractive electrospray ionization-mass spectrometry (iEESI-MS) analysis of six β-agonists, including salbutamol (Sal), clenbuterol (Cle), ractopamine (Rac), terbutaline (Ter), tulobuterol (Tul), brombuterol (Bro), in pork tissue samples. Single sample analysis only required 1 min. The linear range of detection was about 0.01-1000 μg/kg (R(2) > 0.9994). The limit-of-detection (LOD) varied from 0...
November 7, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28947443/uk-based-prospective-cohort-study-to-anglicise-and-validate-the-face-q-skin-cancer-module-in-patients-with-facial-skin-cancer-undergoing-surgical-reconstruction-the-promiscr-patient-reported-outcome-measure-in-skin-cancer-reconstruction-study
#11
Thomas Dobbs, Hayley A Hutchings, Iain S Whitaker
INTRODUCTION: Skin cancer is the most common malignancy worldwide, often occurring on the face, where the cosmetic outcome of treatment is paramount. A number of skin cancer-specific patient-reported outcome measures (PROMs) exist, however none adequately consider the difference in type of reconstruction from a patient's point of view. It is the aim of this study to 'anglicise' (to UK English) a recently developed US PROM for facial skin cancer (the FACE-Q Skin Cancer Module) and to validate this UK version of the PROM...
September 24, 2017: BMJ Open
https://www.readbyqxmd.com/read/28947390/level-of-systemic-inflammation-and-endothelial-injury-is-associated-with-cardiovascular-dysfunction-and-vasopressor-support-in-post-cardiac-arrest-patients
#12
John Bro-Jeppesen, Pär I Johansson, Jesper Kjaergaard, Michael Wanscher, Sisse R Ostrowski, Mette Bjerre, Christian Hassager
AIM: Post-cardiac arrest syndrome (PCAS) is characterized by a sepsis-like inflammatory response and hemodynamic instability. We investigated the associations between systemic inflammation, endothelial damage and hemodynamic parameters including vasopressor support in patients with out-of-hospital cardiac arrest (OHCA). METHODS: In this post-hoc study, we analysed data from 163 comatose patients included at a single center in the Target Temperature Management (TTM) trial, randomly assigned to TTM at 33°C or 36°C for 24h...
September 23, 2017: Resuscitation
https://www.readbyqxmd.com/read/28869019/-treatment-of-recurrent-posterior-epistaxis
#13
Søren Pauli Bro, Jesper Bille, Kristian Bruun Petersen
30% of the patients presenting with epistaxis at emergency wards and otorhinolaryngeal specialist departments have posterior bleeding. Traditional treatment with packing often leads to initial treatment failure, and many patients experience recurrent bleeding within the following month. Recurrent posterior epistaxis should be treated with local electrocautery or endoscopic ligation of the sphenopalatine artery to reduce patient discomfort, hospital stay, risk of treatment failure and recurrence.
August 21, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28852788/development-and-application-of-a-sampling-method-for-the-determination-of-reactive-halogen-species-in-volcanic-gas-emissions
#14
Julian Rüdiger, Nicole Bobrowski, Marcello Liotta, Thorsten Hoffmann
Volcanoes release large amounts of reactive trace gases including sulfur and halogen-containing species into the atmosphere. The knowledge of halogen chemistry in volcanic plumes can deliver information about subsurface processes and is relevant for the understanding of the impact of volcanoes on atmospheric chemistry. In this study, a gas diffusion denuder sampling method using 1,3,5-trimethoxybenzene (1,3,5-TMB)-coated glass tubes for the in situ derivatization of reactive halogen species (RHS) was characterized by a series of laboratory experiments...
October 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28716995/impact-of-gp-reminders-on-follow-up-of-abnormal-cervical-cytology-a-before-after-study-in-danish-general-practice
#15
Bettina Kjær Kristiansen, Berit Andersen, Flemming Bro, Hans Svanholm, Peter Vedsted
BACKGROUND: Dysplasia may progress because of a loss to follow-up after an abnormal cervical cytology. Approximately 18% of Danish women postpone the recommended follow-up, which depends on the cytology results. AIM: To investigate if a reminder to the GP about missed follow-up could reduce the proportion of women who fail to act on a recommended follow-up, and to analyse the effect on sociodemographic and general practice variations. DESIGN AND SETTING: A national electronic GP reminder system was launched in Denmark in 2012 to target missed follow-up after screening, opportunistic testing, or surveillance indication...
August 2017: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/28697531/pain-reduction-in-the-recanalization-of-chronic-iliofemoral-venous-occlusion-with-a%C3%A2-new-scoring-balloon-a-retrospective-series-in-10-consecutive-patients
#16
Christian Hohl, Anders Bro, Ronald Bruce Friedberg
No abstract text is available yet for this article.
November 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28686096/the-community-dental-service-in-abertawe-bro-morgannwg-university-health-board
#17
David Howell James Davies
No abstract text is available yet for this article.
July 2, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/28678731/the-potential-of-gelam-honey-in-promoting-the-proliferative-phase-of-corneal-reepithelialization
#18
Muhammad Fairuz Azmi, Norzana Abd Ghafar, Jemaima Che Hamzah, Ng Sook Luan, Chua Kien Hui
OBJECTIVE: The aim of this study is to investigate the potential bene ts of Gelam honey (GH) in promoting proliferation of ex vivo cor- neal epithelial cells (CECs) and its effects on the phenotypical features. MATERIALS AND METHODS: Corneal epithelial cells were isolated from the corneas of rabbits (n = 6). The optimal dose of GH for CEC proliferation in both basal medium (BM) and cornea medium (CM) was determined via MTT (3-[4, 5-dimethyl thiazolyl-2]-2, 5-diphenyl tetrazolium bro- mide) assay...
November 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28629377/quantitative-phosphoproteome-on-the-silkworm-bombyx-mori-cells-infected-with-baculovirus
#19
Jauharotus Shobahah, Shengjie Xue, Dongbing Hu, Cui Zhao, Ming Wei, Yanping Quan, Wei Yu
BACKGROUND: Bombyx mori has become an important model organism for many fundamental studies. Bombyx mori nucleopolyhedrovirus (BmNPV) is a significant pathogen to Bombyx mori, yet also an efficient vector for recombinant protein production. A previous study indicated that acetylation plays many vital roles in several cellular processes of Bombyx mori while global phosphorylation pattern upon BmNPV infection remains elusive. METHOD: Employing tandem mass tag (TMT) labeling and phosphorylation affinity enrichment followed by high-resolution LC-MS/MS analysis and intensive bioinformatics analysis, the quantitative phosphoproteome in Bombyx mori cells infected by BmNPV at 24 hpi with an MOI of 10 was extensively examined...
June 19, 2017: Virology Journal
https://www.readbyqxmd.com/read/28626867/kind-of-blue-a-systematic-review-and-meta-analysis-of-music-interventions-in-cancer-treatment
#20
REVIEW
Margrethe Langer Bro, Kira Vibe Jespersen, Julie Bolvig Hansen, Peter Vuust, Niels Abildgaard, Jeppe Gram, Christoffer Johansen
OBJECTIVES: Music may be a valuable and low-cost coping strategy for cancer patients. We conducted a systematic review and meta-analysis to identify the psychological and physical effects of music interventions in cancer treatment. METHODS: We included randomized, controlled trials with adult patients in active cancer treatment exposed to different music interventions versus control conditions. Qualitative studies and systematic reviews were excluded. We identified a total of 2624 records through 2 systematic searches (June 2015 and September 2016) in PubMed, Scopus, EMBASE, Cinahl, Web of Science, Cochrane, and PsycINFO and used Risk of Bias Assessment, GRADE and Checklist for Reporting Music-Based Interventions to evaluate the music applied and quality of the studies...
June 18, 2017: Psycho-oncology
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