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https://www.readbyqxmd.com/read/29777849/non-invasive-diagnostic-methods-for-better-screening-of-peripheral-arterial-disease
#1
REVIEW
Neelamshobha Nirala, R Periyasamy, Awanish Kumar
BACKGROUND: Peripheral arterial disease (PAD) is a common circulatory problem in which narrowed arteries reduce blood flow to extremities usually legs. It does not receive enough blood flow to keep up with demand. This causes symptoms, most notably leg pain while walking which is known as claudication. It is a common manifestation of type II Diabetes, but the relationship between other vascular diseases and lower limb (LL)-PAD has been poorly understood and investigated. METHODS: When assessing a patient with clinically LLPAD, two questions are in order to establish a diagnosis: one is non-invasive testing and other is invasive...
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29777842/nationally-representative-readmission-factors-in-patients-with-claudication-and-critical-limb-ischemia
#2
Rennier A Martinez, Michelle Shnayder, Joshua Parreco, Lukas Gaffney, Marcus Eby, Nicholas Cortolillo, Michael Lopez, Jack Zeltzer
INTRODUCTION: Hospital readmissions are not only associated with increased mortality, morbidity and costs but also, with current healthcare reform, tied to significant financial and administrative penalties. Some studies show that patients undergoing vascular surgery may have higher than average readmission rates. The recently released Nationwide Readmission Database (NRD) is the most comprehensive national source of readmission data, gathering discharge information from 22 geographically dispersed states, accounting for 51...
May 16, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29774187/multimodality-imaging-for-the-quantitative-assessment-of-mitral-regurgitation
#3
REVIEW
Pei G Chew, Katrina Bounford, Sven Plein, Dominik Schlosshan, John P Greenwood
The natural history of mitral regurgitation (MR) results in significant morbidity and mortality. Innovations in non-invasive imaging have provided new insights into the pathophysiology and quantification of MR, in addition to early detection of left ventricular (LV) dysfunction and prognostic assessment in asymptomatic patients. Transthoracic (TTE) and transesophageal (TOE) echocardiography are the mainstay for diagnosis, assessment and serial surveillance. However, the advance from 2D to 3D imaging leads to improved assessment and characterization of mitral valve (MV) disease...
April 2018: Quantitative Imaging in Medicine and Surgery
https://www.readbyqxmd.com/read/29773857/development-and-worldwide-use-of-non-lethal-and-minimal-population-level-impact-protocols-for-the-isolation-of-amphibian-chytrid-fungi
#4
Matthew C Fisher, Pria Ghosh, Jennifer M G Shelton, Kieran Bates, Lola Brookes, Claudia Wierzbicki, Gonçalo M Rosa, Rhys A Farrer, David M Aanensen, Mario Alvarado-Rybak, Arnaud Bataille, Lee Berger, Susanne Böll, Jaime Bosch, Frances C Clare, Elodie A Courtois, Angelica Crottini, Andrew A Cunningham, Thomas M Doherty-Bone, Fikirte Gebresenbet, David J Gower, Jacob Höglund, Timothy Y James, Thomas S Jenkinson, Tiffany A Kosch, Carolina Lambertini, Anssi Laurila, Chun-Fu Lin, Adeline Loyau, An Martel, Sara Meurling, Claude Miaud, Pete Minting, Serge Ndriantsoa, Simon J O'Hanlon, Frank Pasmans, Tsanta Rakotonanahary, Falitiana C E Rabemananjara, Luisa P Ribeiro, Dirk S Schmeller, Benedikt R Schmidt, Lee Skerratt, Freya Smith, Claudio Soto-Azat, Giulia Tessa, Luís Felipe Toledo, Andrés Valenzuela-Sánchez, Ruhan Verster, Judit Vörös, Bruce Waldman, Rebecca J Webb, Che Weldon, Emma Wombwell, Kelly R Zamudio, Joyce E Longcore, Trenton W J Garner
Parasitic chytrid fungi have emerged as a significant threat to amphibian species worldwide, necessitating the development of techniques to isolate these pathogens into culture for research purposes. However, early methods of isolating chytrids from their hosts relied on killing amphibians. We modified a pre-existing protocol for isolating chytrids from infected animals to use toe clips and biopsies from toe webbing rather than euthanizing hosts, and distributed the protocol to researchers as part of the BiodivERsA project RACE; here called the RML protocol...
May 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29773286/acral-melanoma-mimicking-toe-gangrene-in-diabetic-foot
#5
Yunfang Han, Zhongzhi Jia
No abstract text is available yet for this article.
May 14, 2018: European Journal of Vascular and Endovascular Surgery
https://www.readbyqxmd.com/read/29772495/walking-variations-in-healthy-women-wearing-high-heeled-shoes-shoe-size-and-heel-height-effects
#6
Enrica Di Sipio, Giulia Piccinini, Cristiano Pecchioli, Marco Germanotta, Chiara Iacovelli, Chiara Simbolotti, Arianna Cruciani, Luca Padua
BACKGROUND: The use of high heels is widespread in modern society in professional and social contests. Literature showed that wearing high heels can produce injurious effects on several structures from the toes to the pelvis. No studies considered shoe length as an impacting factor on walking with high heels. RESEARCH QUESTION: The aim of this study is to evaluate walking parameters in young healthy women wearing high heels, considering not only the heel height but also the foot/shoe size...
May 3, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29770837/systematic-investigations-of-endogenous-cortisol-and-cortisone-in-nails-by-lc-ms-ms-and-correlation-to-hair
#7
Tina M Binz, Franziska Gaehler, Clarissa D Voegel, Mathias Hofmann, Markus R Baumgartner, Thomas Kraemer
Hair samples are increasingly used for measuring the long-term stress mediator cortisol. However, hair is not always available and nails (finger or toe), as a keratinized matrix, may be an alternative to hair. In order to measure cortisol and cortisone in the nail matrix, an LC-MS/MS method has been developed and validated using 13 C3 -labeled surrogate analytes. Both analytes were measured in ESI negative mode as formic acid adducts. Different sample preparation techniques were assessed, and single-step extraction in methanol was established for determination of cortisone and cortisol in the nail matrix...
May 17, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29769833/effects-of-knee-alignments-and-toe-clip-on-frontal-plane-knee-biomechanics-in-cycling
#8
Guangping Shen, Songning Zhang, Hunter J Bennett, James C Martin, Scott E Crouter, Eugene C Fitzhugh
Effects of knee alignment on the internal knee abduction moment (KAM) in walking have been widely studied. The KAM is closely associated with the development of medial knee osteoarthritis. Despite the importance of knee alignment, no studies have explored its effects on knee frontal plane biomechanics during stationary cycling. The purpose of this study was to examine the effects of knee alignment and use of a toe clip on the knee frontal plane biomechanics during stationary cycling. A total of 32 participants (11 varus, 11 neutral, and 10 valgus alignment) performed five trials in each of six cycling conditions: pedaling at 80 rpm and 0...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29765181/assessment-of-leg-muscle-activity-using-toe-tapping-in-patients-with-parkinson-s-disease-comparison-of-two-types-of-toe-tapping
#9
Seira Taniguchi, Ferdinand Peper, Tetsuya Shimokawa
[Purpose] This study investigates two types of toe tapping, i.e., "closed," with both feet on the floor, and "open," in which the foot does not touch the ground, and evaluates their usefulness in combination with monitoring of muscle activity during toe tapping. [Subjects and Methods] The study enrolled 11 patients with Parkinson's disease (PD) and 9 controls (Controls). The tibialis anterior (TA) and gastrocnemius (GS) muscle activity during toe tapping was measured using surface electromyography...
May 2018: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29765178/gender-difference-in-factors-affecting-the-medial-longitudinal-arch-height-of-the-foot-in-healthy-young-adults
#10
Katsuhito Nagano, Risako Okuyama, Natsuki Taniguchi, Tomoki Yoshida
[Purpose] Medial longitudinal arch (MLA) height is associated with various injuries and diseases and gender differences, if any. This study aimed to examine factors affecting the MLA height associated with gender differences in healthy subjects with no orthopedic disorders. [Subjects and Methods] This study included 36 healthy adults (19 males, 17 females; mean age, 21.8 ± 3.6 years; body mass index, 21.1 ± 2.0 kg/m2 ). Their height, body weight, foot length, muscle strength of the tibialis posterior muscle (TPM), toe-gripping strength, hallux valgus angle, inversion microdactylia angle, angle of leg-heel alignment, femoro-tibial angle, and navicular height were measured...
May 2018: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29764833/early-prosthetic-valve-endocarditis-after-transcatheter-aortic-valve-implantation-using-st-jude-medical-portico-valve
#11
Abdalla Ibrahim, Aneeq Ahmed, Thomas Kiernan, Samer Arnous
An 87-year-old woman presented to the emergency department with a 2-week history of progressively worsening shortness of breath, fever and generalised myalgia. She underwent a transcatheter Portico aortic valve implantation for severe symptomatic aortic stenosis 3 months prior to this presentation. Examination revealed a temperature of 40°C and a systolic murmur in the aortic area. Inflammatory markers were elevated, and blood cultures were positive for methicillin-sensitive Staphylococcus aureus A possible diagnosis of infective endocarditis was made as one major and one minor criterion in the modified Duke criteria were fulfilled...
May 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29759137/low-amounts-of-bisecting-glycans-characterize-cerebrospinal-fluid-borne-igg
#12
Jasmin Knopf, Iryna Magorivska, Juan M Maler, Philipp Spitzer, Rostyslav Bilyy, Mona H C Biermann, Kateryna Hychka, Albert Bondt, Manfred Wuhrer, Rene E M Toes, Georg Schett, Martin Herrmann, Luis E Muñoz
Immunoglobulin G (IgG) harbors a conserved N-glycosylation site which is important for its effector functions. Changes in glycosylation of IgG occur in many autoimmune diseases but also in physiological conditions. Therefore, the glycosylation pattern of serum IgG is well characterized. However, limited data is available on the glycosylation pattern of IgG in cerebrospinal fluid (CSF) compared to serum. Here, we report significantly reduced levels of bisected glycans in CSF IgG. Galactosylation and sialylation of IgG4 also differed significantly...
July 15, 2018: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/29757728/tumors-in-von-hippel-lindau-syndrome-from-head-to-toe-comprehensive-state-of-the-art-review
#13
Dhakshinamoorthy Ganeshan, Christine O Menias, Perry J Pickhardt, Kumaresan Sandrasegaran, Meghan G Lubner, Preetha Ramalingam, Sanjeev Bhalla
No abstract text is available yet for this article.
May 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29757449/composite-hemangioendothelioma-settled-in-the-paraspinal-region-a-rare-case-report
#14
Sevki Gok, Mehmet Zafer Berkman, Eyup Baykara
Composite Hemangioendothelioma (CHE) is a very rare, low-grade malignant vascular tumor. It is most commonly seen as one or more nodules on both sides of the fingers and toes. This tumor is rarely settled in the paraspinal muscles. The age of onset is usually between the ages of 21 and 72 (1), with average age of 39.5-41 years. The treatment is gross total removal of the lesion. The definitive diagnosis is made histopathologically. Our case was a 54-year-old male patient. He had a complaint of low back pain...
April 24, 2018: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29755399/leg-prosthesis-with-somatosensory-feedback-reduces-phantom-limb-pain-and-increases-functionality
#15
Caroline Dietrich, Sandra Nehrdich, Sandra Seifert, Kathrin R Blume, Wolfgang H R Miltner, Gunther O Hofmann, Thomas Weiss
Phantom limb pain (PLP) develops in most patients with lower limb amputation. Changes in the peripheral and central nervous system (CNS) are hypothesized to contribute to PLP. Based on ideas to modify neural reorganization within the CNS, the aim of the study was to test, whether prostheses with somatosensory feedback might help to reduce PLP, and increase the functionality of movement with a prosthesis. We therefore equipped the prostheses of 14 lower leg amputees with a simple to use feedback system that provides electrocutaneous feedback to patients' thigh whenever the foot and toes of the prosthesis touch the ground...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29754186/flexor-hallucis-longus-transfer-clinical-outcome-through-a-single-incision-for-chronic-achilles-tendon-rupture
#16
Hossam Abubeih, Mohamed Khaled, Waleed Riad Saleh, Galal Z Said
PURPOSE: The aim of this study is to evaluate the clinical outcome of single-incision flexor hallucis longus tendon transfer in chronic Achilles tendon rupture. METHODS: A prospective study of a series of cases of chronic Achilles tendon rupture that were treated with single-incision flexor hallucis longus tendon transfer, from April 2015 to December 2016. The study included 21 patients (15 men and 6 women), with mean age 40.3 ± 17.5 years. The average follow-up time was 15 (12-24) months...
May 12, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29753996/risk-factors-for-diabetic-foot-ulcer-recurrence-a-prospective-2-year-follow-up-study-in-egypt
#17
Walaa A Khalifa
OBJECTIVES: To determine the frequency of diabetic foot ulcer recurrence and its potential risk factors. METHODS: This study included 93 patients with type 2 diabetes and followed for 2 years after primary healed foot ulceration. Demographic, diabetes related, comorbid and ulcer related variables were investigated as risk factors. Multiple logistic regression analysis was used to identify independent risk factors. RESULTS: 61.3% of patients had recurrent ulcers particularly in the forefoot (33...
December 28, 2017: Foot
https://www.readbyqxmd.com/read/29751719/-panax-notoginseng-extract-combined-with-alprostadil-in-treatment-of-arteriosclerosis-obliterans-meta-analysis
#18
(no author information available yet)
To evaluate the clinical efficacy of Panax notoginseng extract combined with alprostadil in the treatment of arteriosclerosis occlusion and investigate its effects on the degree of atherosclerosis. CNKI, Wanfang, VIP journal database, Chinese biomedical literature database(CBM), PubMed, the Cochrane Library and Science Citation Index(SCI) database were searched between inception to December 2017 for relevant studies. Two researchers independently screened and extracted the literature in strict accordance with the inclusion criteria and exclusion criteria...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29751408/can-beaver-impact-promote-river-renaturalization-the-example-of-the-raba-river-southern-poland
#19
Elżbieta Gorczyca, Kazimierz Krzemień, Mateusz Sobucki, Krzysztof Jarzyna
The European beaver (Castor fiber) was reintroduced in the Polish Carpathians in the 1980s after a few centuries of absence. It gradually colonized suitable habitats in the Raba River valley and elsewhere. The question arises as to whether beaver activity can play a role in the local improvement of hydromorphological conditions and spontaneous renaturalization of the Raba River channel. Field surveys were performed in morphodynamically and structurally homogeneous reaches of the river. Traces of beaver activity were identified and used to estimate the studied beaver population...
February 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29750746/ingrown-toenails-during-chemotherapy-and-stem-cell-transplantation-in-children-with-hematological-malignancies-and-solid-tumors
#20
Daiki Hori, Ryoji Kobayashi, Daisuke Suzuki, Hirozumi Sano, Kunihiko Kobayashi
BACKGROUND: At our institution, we noted that children with hematological malignancies and solid tumors often suffered from ingrown toenails (IGTNs) during hospitalization for chemotherapy and stem cell transplantation. However, only few reports have dealt with IGTNs in the above setting. PROCEDURE: Between August 2007 and July 2017, 180 children who received treatment for hematological malignancies and solid tumors at our institute were enrolled in this study. Twelve patients with insufficient data and 7 patients with past histories of IGTNs were excluded...
May 10, 2018: Journal of Pediatric Hematology/oncology
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