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https://www.readbyqxmd.com/read/29150768/toe-web-intertrigo-in-kaposi-s-sarcoma-patients-a-microbiological-study-in-a-large-cohort-of-patients
#1
G Nazzaro, A Tourlaki, B Scoppio, A Restelli, A Grancini, L Brambilla
Kaposi 's sarcoma (KS) is a rare multifocal angioproliferative disease associated with human herpes virus 8 (HHV-8) infection, characterized by cutaneous nodules or plaques especially on the lower limbs. Some skin modifications, such as chronic lymphedema, plantar hyperkeratosis and interdigital desquamation, may be associated with consequent impairment of the local immunosurveillance and increased risk of some bacterial or mycotic infections. With the objective of evaluating if bacterial or mycotic infections in KS patients are supported by different microorganisms compared to control patients, we performed an observational retrospective study, comparing positive cultural swabs of interdigital intertrigo of KS patients with positive cultural swabs of interdigital intertrigo of patients admitted to our dermatologic unit during the last 10 years...
November 17, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29148421/a-validation-study-of-the-simple-psoriatic-arthritis-screening-sipas-questionnaire-to-screen-psoriasis-patients-for-psoriatic-arthritis
#2
Fausto Salaffi, Marco Di Carlo, Michele Maria Luchetti, Eleonora Di Donato, Anna Campanati, Devis Benfaremo, Massimiliano Nicolini, Marina Carotti, Alfredo Giacchetti, Giulia Ganzetti, Leonardo Bugatti, Armando Gabrielli, Anna Maria Offidani
OBJECTIVES: To validate in a multicentric cohort of patients a self-administered PsA screening tool, called Simple Psoriatic Arthritis Screening (SiPAS) questionnaire, to screen psoriasis patients for signs and symptoms of PsA. METHODS: The SiPAS questionnaire was validated in a multicentric Italian cohort of psoriasis patients referred to two rheumatological centres. RESULTS: A total of 202 psoriasis patients were screened with SiPAS in the validation study...
November 16, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29148242/infrapopliteal-peripheral-arterial-disease-and-critical-limb-ischemia-the-time-has-come-for-collaborative-streamlined-diagnostic-and-treatment-paradigms
#3
EDITORIAL
Michael S Levy
The diagnosis, surveillance, and management of infrapopliteal critical limb ischemia remain inconsistent among clinicians. This study demonstrates that using an absolute ankle pressure of >73 mm Hg or an absolute toe pressure increase of 1 mm Hg or greater post endovascular intervention in patients with infrapopliteal critical limb ischemia may be predictive of a reduction in target limb revascularization, amputation, and death. This study highlights the need for vascular societies to come together to promote standardized screening, surveillance, and treatment paradigms for this complex population...
November 15, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29148083/macroscopic-and-microscopic-analyses-in-flexor-tendons-of-the-tarsometatarso-phalangeal-joint-of-ostrich-struthio-camelus-foot-with-energy-storage-and-shock-absorption
#4
Rui Zhang, Dianlei Han, Gang Luo, Lei Ling, Guoyu Li, Qiaoli Ji, Jianqiao Li
Flexor tendons function as energy storage and shock absorption structures in the tarsometatarso-phalangeal joint (TMTPJ) of ostrich feet during high-speed and heavy-load locomotion. In this study, mechanisms underlying the energy storage and shock absorption of three flexor tendons of the third toe were studied using histology and scanning electron microscopy (SEM). Macroscopic and microscopic structures of the flexor tendons in different positions of TMTPJ were analyzed. Histological slices showed collagen fiber bundles of all flexor tendons in the middle TMTPJ were arranged in a linear-type, but in the proximal and distal TMTPJ, a wavy-type arrangement was found in the tendon of the M...
November 17, 2017: Journal of Morphology
https://www.readbyqxmd.com/read/29147567/leriche-syndrome-the-inferior-mesenteric-artery-saves-the-lower-extremity
#5
Mahmoud Assaad, Sunit Tolia, Marcel Zughaib
Leriche syndrome presents as a triad of claudication, erectile dysfunction, and decreased distal pulses. This syndrome is a well-recognized entity in the current literature; however, our case report illustrates that even with a severe ostial lesion of the inferior mesenteric artery, the vessel was able to provide perfusion to bilateral lower extremities. The patient presented with symptoms of progressive pain in his right leg that limited his physical activity and he also complained of paresthesia, pallor, and cold skin with black discoloration of his toes bilaterally...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/29144039/chronic-plaque-on-the-great-toe-of-a-10-year-old-boy
#6
Trevor Hansen, Jessica Smith, Tracy Funk
No abstract text is available yet for this article.
November 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29143442/development-of-biomimetic-thermoplastic-polyurethane-fibroin-small-diameter-vascular-grafts-via-a-novel-electrospinning-approach
#7
Emily Yu, Hao-Yang Mi, Jue Zhang, James A Thomson, Lih-Sheng Turng
A new electrospinning approach for fabricating vascular grafts with a layered, circumferentially aligned, and micro-wavy fibrous structure similar to natural elastic tissues has been developed. The customized electrospinning collector was able to generate wavy fibers using the dynamic "jump rope" collecting process, which also solved the sample removal problem for mandrel-type collectors. In this study, natural silk fibroin and synthetic thermoplastic polyurethane (TPU) were combined at different weight ratios to produce hybrid small-diameter vascular grafts...
November 16, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29142581/an-unexpected-reason-for-isolated-foot-drop-acute-stroke
#8
Eylem Kuday Kaykisiz, Erden Erol Unluer
The differential diagnosis of acute weakness (AW) in emergency departments (ED) is broad and includes both neurological and medical reasons. We describe an 81-year-old female patient with cortical infarct presenting with sudden onset isolated foot drop, which to the best of our knowledge, was the third case in English literature. An 81-year-old female was admitted to our ED with a 12-hour history of left-sided foot drop. Her motor strength was normal throughout the upper and lower extremities, except for weakness in the left ankle and toe dorsiflexors...
September 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29142272/individuals-of-the-common-namib-day-gecko-vary-in-how-adaptive-simplification-alters-sprint-biomechanics
#9
Clint E Collins, Timothy E Higham
Locomotion inextricably links biomechanics to ecology as animals maneuver through mechanically challenging environments. Faster individuals are more likely to escape predators, surviving to produce more offspring. Fast sprint speed evolved several times in lizards, including geckos. However, the underlying mechanisms determining performance await discovery in many clades. Novel morphological structures influence these mechanisms by adding complexity to the government of locomotion. Gecko adhesion coevolves with modified muscles, tendons, and reflexes...
November 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29142095/patterns-of-intermuscular-inhibitory-force-feedback-across-cat-hindlimbs-suggest-a-flexible-system-for-regulating-whole-limb-mechanics
#10
Mark A Lyle, T Richard Nichols
Prior work has suggested that Golgi tendon organ feedback, via its distributed network linking muscles spanning all joints, could be used by the nervous system to help regulate whole limb mechanics if appropriately organized. We tested this hypothesis by characterizing the patterns of intermuscular force dependent feedback between the primary extensor muscles spanning the knee, ankle and toes in decerebrate cat hindlimbs. Intermuscular force feedback was evaluated by stretching tendons of selected muscles in isolation and in pairwise combinations and then measuring the resulting force dependent intermuscular interactions...
November 15, 2017: Journal of Neurophysiology
https://www.readbyqxmd.com/read/29140732/a-rare-form-of-ankyloblepharon-filiforme-adnatum-associated-with-the-hay-wells-syndrome-and-a-c-1709t-c-mutation-on-the-tp63-gene
#11
Michal Koubek, Kristýna Strakošová, Juraj Timkovič, Dagmar Grečmalová, Aneta Orlíková, Hana Burčková, Hana Wiedermannová, Petr Mašek
INTRODUCTION: Ankyloblepharon filiforme adnatum associated with Hay-Wells syndrome is a rare congenital disease caused by mutations in TP63 gene on the 3q27 chromosome. Here, we report a case of a new-born suffering from this syndrome in whom we detected a mutation c.1709T>C not previously included in the Ensemble database. CASE DESCRIPTION: A girl delivered in the 34th week of gestation from a physiological pregnancy was born with extensive burn-like skin defects, ankyloblepharon filiforme adnatum, palate cleft, onychodystrophy of all limbs and syndactyly of toes...
November 15, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29137568/first-dorsal-metatarsal-artery-perforator-flap-to-cover-great-toe-defect
#12
Roongsak Limthongthang, Perajit Eamsobhana
BACKGROUND: There were very few options available for distal foot and toe defects that required a vascularized flap for coverage. As such, the use of a free flap was often justified in this region of the foot. The use of perforator flaps has created a new subset of local tissue transfer alternatives that increases the potential that the difficulties associated with microvascular tissue transfers could be avoided. The first dorsal metatarsal artery (FDMA) perforator flap was one variant of this new type of tissue transfer...
September 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29137090/diabetic-and-sympathetic-influences-on-the-water-permeability-barrier-function-of-human-skin-as-measured-using-transepidermal-water-loss-a-case-control-study
#13
Seung Hoon Han, Ji Woong Park
The presence of long-standing hyperglycemic conditions has been suggested to lead to many skin problems associated with an impaired skin barrier function. However, the relationship between impaired skin barrier status and altered peripheral nervous system function has not yet been determined. The purpose of this study was to investigate the water evaporation rate as a measure of the permeability barrier function of diabetic skin and its relationship to diabetic sensorimotor polyneuropathy (DSPN) and peripheral autonomic neuropathy (PAN) using well-controlled confounding variables...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29135278/acral-fibrokeratoma-a-rare-pedal-soft-tissue-mass
#14
Dyane E Tower, Jeffrey R Hammond
Acral fibrokeratoma (AF) is a rare soft tissue mass, more commonly found on the hands and rarely on the feet. This case report of a 40-year-old Hispanic male highlights an unusually located AF on the second toe, describes the clinical presentation, microscopic and pathologic findings, discusses differential diagnoses and presents treatment options.
November 14, 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/29132461/-clinical-features-of-rubinstein-taybi-syndrome-and-novel-mutation-in-the-crebbp-gene-an-analysis-of-one-case
#15
Yuan Li, Shan He, Hong-Ling Zhu
The patient was a girl aged 3 years and 8 months with normal body length and body weight at birth. The girl had feeding difficulty after birth. Her height, body weight, and head circumference were below the 3rd percentile. She had intellectual disability and an unusual facies manifesting as arched shaggy eyebrows, down-slanting palpebral fissures, and broad nasal bridge, but had no a beaked nose, broad thumbs, or big toes. These clinical manifestations were basically consistent with Rubinstein-Taybi syndrome (RSTS)...
November 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29131751/a-diabetic-foot-ulcer-treated-with-hydrogel-and-hyperbaric-oxygen-therapy-a-case-study
#16
P Aguiar, C Amaral, A Rodrigues, A H de Souza
This study reports on the case of an elderly patient, with diabetes, and a bullous wound on the left big toe that led to an amputation of the first and second left toes. The amputation was because of deep injury as it was not able to heal with a conventional treatment. After completing the normal treatment and the removal of a bacterial infection in the lesion, the patient underwent a treatment that was based on a hydrogel gel (0.9% saline solution) and hyperbaric oxygen therapy (HBOT). After 60 sessions of the therapy, almost complete closure of the wound was observed...
November 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/29131660/biomechanical-and-morphometric-properties-of-long-flexor-tendons-of-the-toes-a-cadaver-study
#17
Orhan Beger, Gamze Tumentemür, Coşar Uzun, Elif Nedret Keskinöz, Özlem Elvan, Deniz Uzmansel, Mert Keskinbora, Nurten Erdal, Bahar Taşdelen, Zeliha Kurtoğlu
METHODS: RESULTS: CONCLUSIONS.
November 13, 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/29130658/-vein-nerve-conduit-supported-by-vascular-stent-in-the-regeneration-of-peripheral-nerve-in-rabbits
#18
Wei-Kun Meng, Zhong Huang, Zhen Tan, Liang Li, Qiang Guo, Zhen Zhang, Cheng-Xi Wu, Lei Liu, Fu-Guo Huang, Guang-Lin Wang
OBJECTIVE: To evaluate the effectiveness of autologous vein nerve conduit supported by vascular stent in repairing a 10 mm gap peroneal nerve in white New Zealand rabbits. METHODS: 30 New Zealand rabbits were randomly divided into three groups: autologous nerve group (group A),conventional autologous vein nerve conduit group (group B),autologous vein nerve conduit supported by vascular stent group (group C). 10 mm common peroneal nerve was cut off. In groups A,the peroneal nerve was turned 180 ° before suturing...
September 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29129813/a-novel-duplication-downstream-of-bmp2-in-a-chinese-family-with-brachydactyly-type-a2-bda2
#19
Wen-Bo Wang, Ya-Chao Jia, Zeng Zhang, Jia Xu, Rong-Tai Zuo, Qing-Lin Kang
BACKGROUND: Brachydactyly type A2 (BDA2) is an autosomal dominant disease characterized by the deformation of the middle phalanx of the second fingers and toes. It has been reported to be associated with three genes regulating the osteogenesis, including BMPR1B, GDF5 and BMP2. MATERIALS AND METHODS: 10 BDA2 patients and 7 unaffected individuals in a Chinese family were identified through clinical signs and radiographs. The mutation analyses of BMPR1B, GDF5 and BMP2 gene was performed in all the available family members and 100 control subjects...
November 9, 2017: Gene
https://www.readbyqxmd.com/read/29128666/comparison-of-plantar-pressure-distribution-in-cad-cam-and-prefabricated-foot-orthoses-in-patients-with-flexible-flatfeet
#20
Banafsheh Khodaei, Hassan Saeedi, Maryam Jalali, Maede Farzadi, Ehsan Norouzi
BACKGROUNDS: The effect of foot orthoses on plantar pressure distribution has been proven by researchers but there are some controversies about advantages of custom-made foot orthoses to less expensive prefabricated foot orthoses. METHODS: Nineteen flatfeet adults between 18 and 45 participated in this study. CAD-CAM foot orthoses were made for these patients according to their foot scan. Prefabricated foot orthoses were prepared according to their foot size. Plantar pressure, force and contact area were measured using pedar(®)-x in-shoe system wearing shoe alone, wearing CAD-CAM foot orthoses and wearing prefabricated foot orthoses...
July 13, 2017: Foot
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