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https://www.readbyqxmd.com/read/28640763/the-effectiveness-of-matrix-cauterization-with-bichloracetic-acid-in-the-treatment-of-ingrown-toenails-erratum
#1
(no author information available yet)
No abstract text is available yet for this article.
July 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28625501/hyperkeratosis-and-discoloration-of-the-toenails-in-an-8-year-old
#2
Karlyn Pollack, Barrett Zlotoff, Barbara Wilson
No abstract text is available yet for this article.
June 15, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28619973/marjolin-s-squamous-cell-carcinoma-of-the-hallux-following-recurrent-ingrown-toenail-infections
#3
Wahid Abdul, Barry James O'Neill, Anthony Perera
Marjolin's squamous cell carcinoma (SCC) affecting the toe is rare. Due to resemblance with benign conditions it can often result in misdiagnosis. We report a case of Marjolin's SCC affecting the proximal hallux in a patient with recurrent ingrown toenail infections. A 58-year-old woman with a background of wedge resections for ingrown toenail and distal phalanx amputation for osteomyelitis presented with pain and hyperkeratotic raised ulcer around the proximal phalanx. MRI scan revealed soft tissue mass infiltrating the proximal phalanx with biopsies confirming a SCC...
June 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28611998/recurrent-paronychia-as-a-presenting-manifestation-of-pemphigus-vulgaris-a-case-report
#4
Vijay Zawar, Manoj Pawar, Shrikant Kumavat
Nail involvement in pemphigus vulgaris (PV) is an unusual clinical finding. The most common clinical manifestations include chronic paronychia and onychomadesis. We report an adult female patient with PV who initially presented with chronic paronychia of multiple fingernails and toenails before the onset of vesiculobullous eruptions. Later on, after complete resolution, there was recurrence of pemphigus presenting as hemorrhagic paronychia of the left index finger. Systemic treatment with corticosteroids and azathioprine led to complete resolution of mucocutaneous lesions as well as nail manifestations...
March 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28611995/an-update-on-the-disappearing-nail-bed
#5
Ralph Daniel, Babaev Meir, Shemer Avner
BACKGROUND: The nail bed may epithelialize and develop dermatoglyphics after long-standing onycholysis. We have called this phenomenon the disappearing nail bed (DNB). DNB may present as a shortened or narrow nail bed. METHODS: Examination of all 20 nails was performed in each patient enrolled to the study. DNB was defined as the presence of a nail which is at least 20% shorter and/or narrower than the identical nail on the opposite hand or foot. Age, sex, and nail history were recorded...
March 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28609764/hemodialysis-and-kidney-transplantation-as-predisposing-conditions-to-onychomycosis
#6
Antonio M S Filho, Carlucci G Ventura, Paulo R Criado, Gilda B Del Negro, Roseli S Freitas, Olinda C Luiz, Mauro C Giudice, Elias D Neto, Gil Benard
BACKGROUND/AIM: Onychomycosis (OM) is one of the commonest superficial fungal infections. Patients undergoing hemodialysis (HD) treatment and kidney transplant recipients (KTR) are considered at risk of contracting fungal infections, but the few published data do not reach the conclusion of whether they are predisposed to OM. This study aimed to determine the prevalence and etiology of OM in these patients and to determine the antifungal susceptibility profile of the isolated fungal species...
June 14, 2017: Nephron
https://www.readbyqxmd.com/read/28594608/etiology-of-onychomycosis-in-patients-turkey
#7
Fatma Pelin Cengiz, Bengu Cevirgen Cemil, Nazan Emiroglu, Anılgülsel Bahalı, Dilek Biyik Ozkaya, Ozlem Su, Nahide Onsun
BACKGROUND: Onychomycosis is the chronic infection of the nails, and it is caused by dermatophytes, Candida, non- dermatophyte molds, Trichosporon genus. METHODS: A retrospective analysis of 225 cases with onychomycosis, diagnosed in a 27-month period at the Department of Dermatoveneorology, Bezmialem Vakif University in Istanbul, and confirmed with culture. RESULTS: The age of patients ranged from 2 to 87 years (41.59 ± 17.61) and females were more commonly affected (120 cases, 53...
June 8, 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28587478/operative-treatment-of-the-ingrown-toenail-with-a-less-invasive-technique-flashback-to-the-original-winograd-technique
#8
Yalkin Camurcu, Hakan Sofu, Ahmet Issin, Nizamettin Kockara, Hakan Saygili
OBJECTIVE: The aim of this study was to evaluate the results of the partial nail plate excision and curettage of nail bed and matrix (the original Winograd technique) in patients with ingrown toenail. MATERIALS AND METHODS: Patients with ingrown toenail who were treated surgically from May 2014 to June 2015, with a minimum follow-up of 1 year were included in this study. Those who had previous ingrown toenail surgery were excluded. Partial nail plate excision with curettage of nail bed and nail matrix was performed for all patients...
June 1, 2017: Foot & Ankle Specialist
https://www.readbyqxmd.com/read/28579250/dna-methylation-of-extracellular-matrix-remodeling-genes-in-children-exposed-to-arsenic
#9
Tania Gonzalez-Cortes, Rogelio Recio-Vega, Robert Clark Lantz, Binh T Chau
Several novel mechanistic findings regarding to arsenic's pathogenesis has been reported and some of them suggest that the etiology of some arsenic induced diseases are due in part to heritable changes to the genome via epigenetic processes such as DNA methylation, histone maintenance, and mRNA expression. Recently, we reported that arsenic exposure during in utero and early life was associated with impairment in the lung function and abnormal receptor for advanced glycation endproducts (RAGE), matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) sputum levels...
June 1, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28573322/plasmonic-gold-nanoparticles-for-detection-of-fungi-and-human-cutaneous-fungal-infections
#10
Tobiloba Sojinrin, João Conde, Kangze Liu, James Curtin, Hugh J Byrne, Daxiang Cui, Furong Tian
Fungi, which are common in the environment, can cause a multitude of diseases. Warm, humid conditions allow fungi to grow and infect humans via the respiratory, digestive and reproductive tracts, genital area and other bodily interfaces. Fungi can be detected directly by microscopy, using the potassium hydroxide test, which is the gold standard and most popular method for fungal screening. However, this test requires trained personnel operating specialist equipment, including a fluorescent microscope and culture facilities...
June 2, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28568975/stable-isotopes-of-carbon-and-nitrogen-as-markers-of-dietary-variation-among-sociocultural-subgroups-of-inuit-in-greenland
#11
Peter Bjerregaard, Christina V L Larsen, Inger K Dahl-Petersen, Bjørn Buchardt
OBJECTIVES: We assessed the use of stable isotopes of carbon and nitrogen as biomarkers for traditional versus store-bought food among the Inuit. Furthermore, we compared the isotope patterns among sociocultural population groups. METHODS: As a part of a country-wide health survey in Greenland during 2005-2010, we analyzed the isotope composition of toenails from 1025 adult Inuit and meat of common species hunted for food. Information on diet and sociocultural variables was collected by interviews...
June 1, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
https://www.readbyqxmd.com/read/28548590/prenatal-exposure-to-neurotoxic-metals-is-associated-with-increased-placental-glucocorticoid-receptor-dna-methylation
#12
Allison A Appleton, Brian P Jackson, Margaret Karagas, Carmen J Marsit
Epigenetic alterations related to prenatal neurotoxic metals exposure may be key in understanding the origins of cognitive and neurobehavioral problems in children. Placental glucocorticoid receptor (NR3C1) methylation has been linked to neurobehavioral risk in early life, but has not been examined in response to neurotoxic metals exposure despite parallel lines of research showing metals exposure and NR3C1 methylation each contribute to a similar set of neurobehavioral phenotypes. Thus, we conducted a study of prenatal neurotoxic metals exposure and placental NR3C1 methylation in a cohort of healthy term singleton pregnancies from Rhode Island, USA (n = 222)...
May 26, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/28529418/intra-individual-right-left-comparative-study-of-medium-depth-peels-in-superficial-nail-abnormalities
#13
Deepashree Daulatabad, Soni Nanda, Chander Grover
BACKGROUND: Superficial nail abnormalities include conditions which produce nail surface changes such as trachyonychia, pitting and ridging. Mostly, this is a neglected area due to the dearth of treatment options. Glycolic acid peeling has been reported to be effective in such cases. AIM: This study aims to assess the safety and efficacy of medium depth peels (70% glycolic acid versus phenol combination peel [8% phenol with 15% trichloroacetic acid]) in patients with superficial nail abnormalities...
January 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28521541/evaluation-of-the-efficacy-and-safety-of-tavaborole-topical-solution-5-in-the-treatment-of-onychomycosis-of-the-toenail-in-adults-a-pooled-analysis-of-an-8-week-post-study-follow-up-from-two-randomized-phase-3-studies
#14
Aditya K Gupta, Steve Hall, Lee T Zane, Shari R Lipner, Phoebe Rich
PURPOSE: The role of topical antifungal agents in the long-term management of toenail onychomycosis is not well established. The current study evaluated durability of clinical benefit of tavaborole topical solution, 5%, for the treatment of toenail onychomycosis. METHODS: We conducted a pooled analysis of 8-week, post-study follow-up (PSFU) data from two phase 3, randomized controlled trials in a subset of patients who experienced complete or almost clear nail (CN) at the end of treatment (week 52); 48 weeks of treatment with once-daily tavaborole compared with placebo in adults with distal subungual onychomycosis was evaluated at week 60...
May 30, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28504456/performance-of-mycology-and-histopathology-tests-for-the-diagnosis-of-toenail-onychomycosis-due-to-filamentous-fungi-dermatophyte-and-non-dermatophyte-moulds
#15
Fernanda G Lavorato, Dávson A Guimarães, Mario G Premazzi, Juan M Piñeiro-Maceira, Andréa R Bernardes-Engemann, Rosane Orofino-Costa
Improvement of laboratory diagnosis of onychomychosis is important so that adequate treatment can be safely implemented. To evaluate and compare the performance of mycological and histopathological examinations in onychomycoses caused by dermatophyte and non-dermatophyte moulds. Patients with lateral/distal subungual onychomycosis in at least one hallux were enrolled in the protocol and assessed via mycological and histopathological tests. The isolation of filamentous fungi was considered the gold standard...
May 15, 2017: Mycoses
https://www.readbyqxmd.com/read/28492600/efinaconazole-solution-10-for-treatment-of-toenail-onychomycosis-in-latino-patients
#16
Fran E Cook-Bolden, Tina Lin
Onychomycosis is a common progressive fungal infection of the nail bed, matrix, or plate leading to destruction and deformity of the toenails and fingernails. The prevalence of onychomycosis is increasing in the United States, particularly in the growing population of Latino patients. In this study, we evaluated the efficacy and safety of efinaconazole solution 10% in Latino patients with onychomycosis. Once-daily application of efinaconazole solution 10% may be an effective topical option for treatment of onychomycosis in this patient population...
April 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28472375/laser-treatment-of-onychomycosis-due-to-neoscytalidium-dimidiatum-an-open-prospective-study
#17
Andreia Pizarro Leverone, Dávson Aguilar Guimarães, Andréa Reis Bernardes-Engemann, Rosane Orofino-Costa
Conventional systemic and topical treatments have proven ineffective for the treatment of onychomycosis caused by Neoscytalidium dimidiatum. Our aim was to evaluate the effectiveness and safety of laser monotherapy for the treatment of onychomycosis caused by this pathogen. Patients with clinical onychomycosis of the toenails and positive results both on direct mycological examination and N. dimidiatum culture underwent four 1064 nm Nd:YAG laser sessions with 6-week intervals between sessions. Participants were monitored by clinical examination supported by dermoscopy, measurement of diseased nail and the onychomycosis severity index (OSI), and by mycological examination for 12 months after completion of treatment...
May 2, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28448084/dna-damage-copper-and-lead-associates-with-cognitive-function-among-older-adults
#18
A Meramat, N F Rajab, S Shahar, R A Sharif
BACKGROUND: A cross sectional study was conducted in a group of 317 subjects older than 60 in Malaysia, aimed to determine risk factors associated with cognitive impairment in older adults, focusing on trace elements and DNA damage. METHOD: Cognitive decline was determined by Montreal Cognitive Assessment (MoCA). Oxidative stress markers (malondialdehyde-MDA and superoxide dismutase-SOD) were determined and DNA damage was assayed using Alkaline Comet Assay. Toenail samples were taken and analyzed using ICP-MS to determine trace element levels...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28441747/associations-between-diet-and-toenail-arsenic-concentration-among-pregnant-women-in-bangladesh-a-prospective-study
#19
Pi-I D Lin, Sabri Bromage, Md Golam Mostofa, Joseph Allen, Emily Oken, Molly L Kile, David C Christiani
This prospective study evaluated the relationship between long-term dietary habits and total arsenic (As) concentration in toenail clippings in a cohort of 1616 pregnant women in the Bangladeshi administrative regions of Sirajdikhan and Pabna Sadar. Diet was assessed at Gestation Week 28 and at Postpartum Month 1, using a locally-validated dish-based semi-quantitative food-frequency questionnaire. Toenail As concentration was analyzed by microwave-assisted acid digestion and inductively coupled plasma mass spectrometry...
April 23, 2017: Nutrients
https://www.readbyqxmd.com/read/28418274/the-gulf-long-term-follow-up-study-gulf-study-biospecimen-collection-at-enrollment
#20
Lawrence S Engel, Richard K Kwok, Aubrey K Miller, Aaron Blair, Matthew D Curry, John A McGrath, Dale P Sandler
The 2010 Deepwater Horizon (DWH) explosion in the Gulf of Mexico led to the largest ever marine oil spill by volume. The GuLF STUDY is investigating possible adverse human health effects associated with oil spill activities. One objective of the study was to utilize biological specimens from study participants to examine spill-related adverse health effects. This study describes the methods for collecting, processing, shipping, and storing specimens during the enrollment phase of the study. GuLF STUDY participants living in Gulf States (Alabama, Florida, Louisiana, Mississippi, and eastern Texas) were eligible to complete a home visit at enrollment, one to three years after the DWH explosion...
April 18, 2017: Journal of Toxicology and Environmental Health. Part A
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