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https://www.readbyqxmd.com/read/28418274/the-gulf-long-term-follow-up-study-gulf-study-biospecimen-collection-at-enrollment
#1
Lawrence S Engel, Richard K Kwok, Aubrey K Miller, Aaron Blair, Matthew D Curry, John A McGrath, Dale P Sandler, Polly Armsby, Susan Baker, Richard D Cohn, Edward E Gaunt, Audra Hodges, David Johndrow, Steven K Ramsey, Mark Stenzel, Patricia Stewart
The 2010 Deepwater Horizon (DWH) explosion in the Gulf of Mexico led to the largest ever marine oil spill by volume. The GuLF STUDY is investigating possible adverse human health effects associated with oil spill activities. One objective of the study was to utilize biological specimens from study participants to examine spill-related adverse health effects. This study describes the methods for collecting, processing, shipping, and storing specimens during the enrollment phase of the study. GuLF STUDY participants living in Gulf States (Alabama, Florida, Louisiana, Mississippi, and eastern Texas) were eligible to complete a home visit at enrollment, one to three years after the DWH explosion...
April 18, 2017: Journal of Toxicology and Environmental Health. Part A
https://www.readbyqxmd.com/read/28394683/relation-between-nail-consistency-and-incidence-of-ingrown-toenails-in-young-male-runners
#2
Ana María Pérez Pico, Elisabeth Verjano, Raquel Mayordomo
BACKGROUND: This study examines the possible influence of factors such as nail shape and consistency, sex, and sports activity on the development of the most common nail disorders in a population of young people. METHODS: The nail plates of 140 young people (66 females and 74 males) were studied. Of these 140 participants, 72 were runners who trained more than 10 hours a week and competed regularly, and 68 did not habitually do any sports activity. Nail shape, consistency, and disorders were examined, taking into account the sex of the participants and their sports activity...
March 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28392547/chromium-exposure-and-risk-of-cardiovascular-disease-in-high-cardiovascular-risk-subjects%C3%A3-nested-case-control-study-in-the-prevention-with-mediterranean-diet-predimed-study
#3
Mario Gutiérrez-Bedmar, Miguel Ángel Martínez-González, Carlos Muñoz-Bravo, Miguel Ruiz-Canela, Alberto Mariscal, Jordi Salas-Salvadó, Ramón Estruch, Dolores Corella, Fernando Arós, Monserrat Fito, José Lapetra, Lluís Serra-Majem, Xavier Pintó, Ángel Alonso-Gómez, Olga Portoles, Miquel Fiol, Mónica Bulló, Olga Castañer, Emilio Ros, Enrique Gómez-Gracia
BACKGROUND: Epidemiological data on chromium (Cr) exposure and the risk of cardiovascular disease (CVD) are still limited. Toenail Cr level (TCL) provides a time-integrated measure reflecting long-term Cr exposure. We measured TCL to assess the hypothesis that long-term Cr exposure was inversely associated with incident CVD in a population at high risk for CVD.Methods and Results:The associations between TCL and CVD were evaluated in a case-control study nested within the "PREvención con DIeta MEDiterránea" (PREDIMED) trial...
April 8, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28391539/interactions-between-dietary-acrylamide-intake-and-genes-for-ovarian-cancer-risk
#4
Janneke G F Hogervorst, Piet A van den Brandt, Roger W L Godschalk, Frederik-Jan van Schooten, Leo J Schouten
Some epidemiological studies observed a positive association between dietary acrylamide intake and ovarian cancer risk but the causality needs to be substantiated. By analyzing gene-acrylamide interactions for ovarian cancer risk for the first time, we aimed to contribute to this. The prospective Netherlands Cohort Study on diet and cancer includes 62,573 women, aged 55-69 years. At baseline in 1986, a random subcohort of 2589 women was sampled from the total cohort for a case cohort analysis approach. Dietary acrylamide intake of subcohort members and ovarian cancer cases (n = 252, based on 20...
April 8, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28387569/associations-between-post-translational-histone-modifications-myelomeningocele-risk-environmental-arsenic-exposure-and-folate-deficiency-among-participants-in-a-case-control-study-in-bangladesh
#5
Jannah Tauheed, Marco Sanchez-Guerra, Jane J Lee, Ligi Paul, Md Omar Sharif Ibne Hasan, Quazi Quamruzzaman, Jacob Selhub, Robert O Wright, David C Christiani, Brent A Coull, Andrea A Baccarelli, Maitreyi Mazumdar
Arsenic exposure may contribute to disease risk in humans through alterations in the epigenome. Previous studies reported that arsenic exposure is associated with changes in plasma histone concentrations. Posttranslational histone modifications have been found to differ between the brain tissue of human embryos with neural tube defects and that of controls. Our objectives were to investigate the relationships between plasma histone 3 levels, history of having an infant with myelomeningocele, biomarkers of arsenic exposure, and maternal folate deficiency...
April 7, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/28379097/examining-the-accuracy-of-visual-diagnosis-of-tinea-pedis-and-tinea-unguium-in-aged-care-facilities
#6
T Goto, G Nakagami, K Takehara, T Nakamura, M Kawashima, Y Tsunemi, H Sanada
OBJECTIVE: The aim of this study was to examine the accuracy of visual diagnosis of tinea pedis (Athlete's foot) and tinea unguium (fungal nail infection), as well as to provide information on skin abnormalities that could help identify these diseases in aged care facilities (long-term care facilities (LTCFs) and nursing homes). METHOD: A multicentre, cross-sectional observational study was conducted in a LTCF and two nursing homes. A dermatologist observed the skin abnormalities in the participants' interdigital and plantar areas, to screen for tinea pedis, and in the participants' toenails, to screen for tinea unguium...
April 2, 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28378259/clinical-laser-treatment-of-toenail-onychomycoses
#7
Antonio Zalacain, Alejandra Merlos, Elena Planell, Erica G Cantadori, Teresa Vinuesa, Miguel Viñas
Onychomycoses are fungal infections of the fingernails or toenails having a prevalence of 3% among adults and accounts for 50% of nail infections. It is caused by dermatophytes, non-dermatophyte filamentous fungi, and yeasts. Compressions and microtraumas significantly contribute to onychomycosis. Laser and photodynamic therapies are being proposed to treat onychomycosis. Laser light (1064 nm) was used to treat onychomycosis in 156 affected toenails. Patients were clinically followed up for 9 months after treatment...
April 4, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28362670/the-effectiveness-of-matrix-cauterization-with-bichloracetic-acid-in-the-treatment-of-ingrown-toenails
#8
Erdinc Terzi, Ulas Guvenc, Belma Tursen, Umit Tursen, Tamer Irfan Kaya
BACKGROUND: Chemical matricectomy is performed mainly by 2 agents, phenol and sodium hydroxide. Chemical matricectomy with phenol has a low recurrence rate and good cosmetic results, but it produces extensive tissue destruction and can result in drainage and a delayed healing time. These adverse effects have brought forward the use of chemical agents such as sodium hydroxide and trichloroacetic acid for matricectomy. OBJECTIVE: This prospective study aimed mainly to evaluate the efficacy of partial nail avulsion and selective chemical cauterization of the matrix using 90% bichloracetic acid (BCA) in the treatment of the ingrown nails...
May 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28347455/domain-specific-effects-of-postnatal-toenail-methylmercury-exposure-on-child-behaviour
#9
Shamshad Karatela, Janis Paterson, Neil I Ward
OBJECTIVE: Very little is known about the relationship between postnatal methylmercury concentrations (via toenails as bioindicator) and behavioural characteristics of Pacific Island children living in New Zealand. The aim of this study was to explore the association between total mercury exposure and different domains of behavioural problems in Pacific children. MATERIALS AND METHODS: A sample of nine-year-old Pacific Island children resident in Auckland, New Zealand participated in this study...
May 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28339058/toenail-selenium-as-an-indicator-of-environmental-exposure-a-cross-sectional-study
#10
Tommaso Filippini, Angela Ferrari, Bernhard Michalke, Peter Grill, Luciano Vescovi, Chiara Salvia, Carlotta Malagoli, Marcella Malavolti, Sabina Sieri, Vittorio Krogh, Annalisa Bargellini, Antonio Martino, Margherita Ferrante, Marco Vinceti
The relation between toxicity and essentiality of selenium (Se) is of growing interest in human health, as the effects may widely differ depending of its different chemical species and the exposure levels. Toenail Se has been proposed as a reliable biomarker of long-term Se exposure, but few studies investigated the correlation between its toenail content and environmental determinants (i.e., dietary food intake). We aimed to determine the relation of toenail Se levels with serum Se species as well as food items...
March 24, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28332720/efficacy-and-safety-of-luliconazole-5-nail-solution-for-the-treatment-of-onychomycosis-a-multicenter-double-blind-randomized-phase-iii-study
#11
Shinichi Watanabe, Hiroshi Kishida, Akihiro Okubo
Onychomycosis is a highly prevalent and intractable disease. The first-line treatment agents are oral preparations, but an effective topical medication has long been desired. The objective was to investigate the efficacy and safety of luliconazole 5% nail solution, an imidazole antifungal agent, for the treatment of patients with onychomycosis. A multicenter, double-blind, randomized phase III study was conducted in Japanese patients with distal lateral subungual onychomycosis affecting the great toenails, with 20-50% clinical involvement...
March 23, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28300915/onychogryphosis-in-tuberous-sclerosis-complex-an-unusual-feature
#12
Xiang-Chun Han, Li-Qiang Zheng, Tie-Gang Zheng
Onychogryphosis is an acquired nail plate change. It often affects the toenail and is characterized by an opaque, yellow-brownish nail plate that is distorted, grossly thickened, elongated, and partly curved resembling a ram's horn. Tuberous sclerosis complex is a multisystem disorder associated with high rates of mental retardation, autism, cognitive impairment, behavioral problems, or seizures. Nail disease can also be associated, which is a concern to patients due to pain and nail distortion. We reported a typical tuberous sclerosis complex patient with distinctive clinical features of a ram's horn nails, which presented a great challenge to surgical treatment and nail restoration...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28294418/a-critical-review-of-improvement-rates-for-laser-therapy-used-to-treat-toenail-onychomycosis
#13
REVIEW
A K Gupta, S G Versteeg
Onychomycosis is a nail infection that is primary caused by dermatophytes. Alternative treatments are needed as current therapies (oral and topical antifungals) have limited effectiveness. Lasers are currently approved by the FDA to temporarily increase the amount of clear nail in onychomycosis patients. Lasers can theoretically elicit fungicidal effects but in practice produce mixed results. This review compared laser-induced improvement rates to FDA-approved indications and traditional onychomycosis treatments...
March 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28291066/quality-of-life-with-ingrown-toenails-a-cross-sectional-study
#14
Alessandra de Pinho Pimenta Borges, Valquíria Pessoa Chinem Pelafsky, Luciane Donida Bartoli Miot, Hélio Amante Miot
No abstract text is available yet for this article.
May 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28286468/a-study-of-dermoscopic-features-of-nail-psoriasis
#15
Ahu Yorulmaz, Ferda Artuz
INTRODUCTION: Dermoscopy is a non-invasive imaging method that enables the evaluation of pigmented and non-pigmented skin lesions. More recently, dermoscopy has been recognized as an effective tool in the diagnosis of nail diseases. AIM: To evaluate the dermoscopic features of nail psoriasis and to assess the relationship between these features and disease severity. MATERIAL AND METHODS: A total of 67 patients with clinically evident nail psoriasis (14 women, 53 men) were prospectively enrolled...
February 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28284420/super-u-technique-for-ingrown-nails
#16
J Correa, J Magliano, C Agorio, C Bazzano
INTRODUCTION AND OBJECTIVES: Ingrown nails are a common problem, seen mostly in young adults. Also known as onychcrypotisis, this condition typically affects the great toenail. Four stages have been defined according to the severity and duration of the condition, and treatment varies from conservative to surgical techniques depending on the stage. We present our experience with this condition, describing the characteristics of our population and surgical treatment, in particular the super U technique...
March 8, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28281037/pathogenic-dermatophytes-survive-in-nail-lesions-during-oral-terbinafine-treatment-for-tinea-unguium
#17
Tomoyuki Iwanaga, Tsuyoshi Ushigami, Kazushi Anzawa, Takashi Mochizuki
Tinea unguium caused by dermatophyte species are usually treated with oral antimycotic, terbinafine (TBF). To understand the mechanisms of improvement and recalcitrance of tinea unguium by oral TBF treatment, a method of quantifying dermatophyte viability in the nail was developed, and the viability of dermatophytes was analyzed in toenail lesions of 14 patients with KOH-positive tinea unguium treated with oral TBF 125 mg/day for up to 16 weeks. Mycological tests, including KOH examination and fungal culture, and targeted quantitative real-time PCR for internal transcribed spacer (ITS) region, including rRNA, were demonstrated at the initial visit and after 8 and 16 weeks of treatment...
March 9, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28263195/toenail-bracing-complicated-with-group-a-beta-haemolytic-streptococcus-infection
#18
Anca Chiriac, Cristina Birsan, Calin Molnar, Simona Stolnicu
No abstract text is available yet for this article.
March 2, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28242214/winograd-method-versus-winograd-method-with-electrocoagulation-in-the-treatment-of-ingrown-toenails
#19
Erdinc Acar
An important component of the Winograd surgical method for an ingrown toenail is total excision of the associated germinal matrix. However, this might not always be accomplished with the procedure. We hypothesized that the surgical results might be improved by adding electrocoagulation of the germinal matrix to the Winograd method. The objective of the present study was to compare the recurrence, satisfaction, and complication rates of the Winograd method with those of the Winograd method with electrocoagulation...
February 24, 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28222839/shope-fibroma-in-the-external-ear-canal-of-a-domestic-rabbit
#20
Shawna J Cikanek, James W Carpenter, Dana M Lindemann, R M Hallman, David Eshar, In Joong Kim, Kelli M Almes
A 5-y-old, intact, 2.5-kg female domestic rabbit was presented because of blood spatter on the wall of its cage and the toenails of its right hind limb. Physical examination revealed a red, gelatinous mass that spanned the width of the right vertical ear canal. Radiographic images revealed a soft-tissue opacity at the base of the right ear, which was superimposed over the tympanic bulla and extended to the pinna. A CT scan revealed that the soft-tissue mass was within the vertical and horizontal portions of the right external ear canal and extended to the level of the tympanic membrane, with no bony involvement...
February 1, 2017: Comparative Medicine
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