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https://www.readbyqxmd.com/read/27933634/middle-cranial-fossa-approach-to-repair-tegmen-defects-assisted-by-three-dimensionally-printed-temporal-bone-models
#1
Sameer Ahmed, Kyle K VanKoevering, Stephanie Kline, Glenn E Green, H Alexander Arts
OBJECTIVES/HYPOTHESIS: To explore the perioperative utility of three-dimensionally (3D)-printed temporal bone models of patients undergoing repair of lateral skull base defects and spontaneous cerebrospinal fluid leaks with the middle cranial fossa approach. STUDY DESIGN: Case series. METHODS: 3D-printed temporal bone models-based on patient-specific, high-resolution computed tomographic imaging-were constructed using inexpensive polymer materials...
December 9, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27932961/patient-specific-electric-field-simulations-and-acceleration-measurements-for-objective-analysis-of-intraoperative-stimulation-tests-in-the-thalamus
#2
Simone Hemm, Daniela Pison, Fabiola Alonso, Ashesh Shah, Jérôme Coste, Jean-Jacques Lemaire, Karin Wårdell
Despite an increasing use of deep brain stimulation (DBS) the fundamental mechanisms of action remain largely unknown. Simulation of electric entities has previously been proposed for chronic DBS combined with subjective symptom evaluations, but not for intraoperative stimulation tests. The present paper introduces a method for an objective exploitation of intraoperative stimulation test data to identify the optimal implant position of the chronic DBS lead by relating the electric field (EF) simulations to the patient-specific anatomy and the clinical effects quantified by accelerometry...
2016: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/27932926/a-dataset-of-fishes-in-and-around-inle-lake-an-ancient-lake-of-myanmar-with-dna-barcoding-photo-images-and-ct-3d-models
#3
Yuichi Kano, Prachya Musikasinthorn, Akihisa Iwata, Sein Tun, Lkc Yun, Seint Seint Win, Shoko Matsui, Ryoichi Tabata, Takeshi Yamasaki, Katsutoshi Watanabe
BACKGROUND: Inle (Inlay) Lake, an ancient lake of Southeast Asia, is located at the eastern part of Myanmar, surrounded by the Shan Mountains. Detailed information on fish fauna in and around the lake has long been unknown, although its outstanding endemism was reported a century ago. NEW INFORMATION: Based on the fish specimens collected from markets, rivers, swamps, ponds and ditches around Inle Lake as well as from the lake itself from 2014 to 2016, we recorded a total of 948 occurrence data (2120 individuals), belonging to 10 orders, 19 families, 39 genera and 49 species...
2016: Biodiversity Data Journal
https://www.readbyqxmd.com/read/27932856/three-dimensional-soft-tissue-analysis-of-the-hand-a-novel-method-to-investigate-effects-of-acromegaly
#4
Inge A Hoevenaren, M A E M Wagenmakers, S H P P Roerink, R T Netea-Maier, D J O Ulrich, Thomas J J Maal
BACKGROUND: Acral overgrowth is a highly common clinical sign in patients with active acromegaly. To what extent this overgrowth persists after long-term remission of acromegaly is largely unknown. Using the new imaging technique of three-dimensional (3D) stereophotogrammetry, it is possible to accurately investigate soft tissue changes of the hand. The aim of the recent study was to compare the 3D soft tissue characteristics of the hands of patients in long-term remission of acromegaly to those of a healthy pair matched control group...
2016: European Journal of Plastic Surgery
https://www.readbyqxmd.com/read/27932507/the-white-gray-sign-identifies-the-central-sulcus-on-3t-high-resolution-t1-weighted-images
#5
O F Kaneko, N J Fischbein, J Rosenberg, M Wintermark, M M Zeineh
BACKGROUND AND PURPOSE: The central sulcus is an important anatomic landmark, but most methods of identifying it rely on variable gyral and sulcal patterns. We describe and assess the accuracy of reduced gray-white contrast along the central sulcus, an observation we term the "white gray sign." MATERIALS AND METHODS: We conducted a retrospective review of 51 fMRIs with a T1-weighted 3D inversion recovery fast-spoiled gradient-echo and concomitant hand-motor fMRI, which served as confirmation for the location of the central sulcus...
December 8, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27932506/synthetic-mri-in-the-detection-of-multiple-sclerosis-plaques
#6
A Hagiwara, M Hori, K Yokoyama, M Y Takemura, C Andica, T Tabata, K Kamagata, M Suzuki, K K Kumamaru, M Nakazawa, N Takano, H Kawasaki, N Hamasaki, A Kunimatsu, S Aoki
BACKGROUND AND PURPOSE: Synthetic MR imaging enables the creation of various contrast-weighted images including double inversion recovery and phase-sensitive inversion recovery from a single MR imaging quantification scan. Here, we assessed whether synthetic MR imaging is suitable for detecting MS plaques. MATERIALS AND METHODS: Quantitative and conventional MR imaging data on 12 patients with MS were retrospectively analyzed. Synthetic T2-weighted, FLAIR, double inversion recovery, and phase-sensitive inversion recovery images were produced after quantification of T1 and T2 values and proton density...
December 8, 2016: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/27931117/resection-planning-in-extratemporal-epilepsy-surgery-using-3d-multimodality-imaging-and-intraoperative-mri
#7
Mark Nowell, Rachel Sparks, Gergely Zombori, Anna Miserocchi, Roman Rodionov, Beate Diehl, Tim Wehner, Mark White, Sebastien Ourselin, Andrew McEvoy, John Duncan
Surgical resection in non-lesional, extratemporal epilepsy, informed by stereoEEG recordings, is challenging. There are no clear borders of resection, and the surgeon is often operating in deep areas of the brain that are difficult to access. We present a technical note where 3D multimodality image integration in EpiNav(TM) is used to build a planned resection model, based on a previous intracranial EEG evaluation. Intraoperative MRI is then used to ensure a complete resection of the planned model. As stereoEEG becomes more common in the presurgical evaluation of epilepsy, these tools will become increasingly important to facilitate targeted cortical resections...
December 8, 2016: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/27930593/usefulness-of-3-dimensional-stereotactic-surface-projection-fdg-pet-images-for-the-diagnosis-of-dementia
#8
Jahae Kim, Sang-Geon Cho, Minchul Song, Sae-Ryung Kang, Seong Young Kwon, Kang-Ho Choi, Seong-Min Choi, Byeong-Chae Kim, Ho-Chun Song
To compare diagnostic performance and confidence of a standard visual reading and combined 3-dimensional stereotactic surface projection (3D-SSP) results to discriminate between Alzheimer disease (AD)/mild cognitive impairment (MCI), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD).[F]fluorodeoxyglucose (FDG) PET brain images were obtained from 120 patients (64 AD/MCI, 38 DLB, and 18 FTD) who were clinically confirmed over 2 years follow-up. Three nuclear medicine physicians performed the diagnosis and rated diagnostic confidence twice; once by standard visual methods, and once by adding of 3D-SSP...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27930514/fully-automated-software-for-mitral-annulus-evaluation-in-chronic-mitral-regurgitation-by-3-dimensional-transesophageal-echocardiography
#9
Iolanda Aquila, Covadonga Fernández-Golfín, Luis Miguel Rincon, Ariana González, Ana García Martín, Rocio Hinojar, Jose Julio Jimenez Nacher, Ciro Indolfi, Jose Luis Zamorano
Three-dimensional (3D) transesophageal echocardiography (TEE) is the gold standard for mitral valve (MV) anatomic and functional evaluation. Currently, dedicated MV analysis software has limitations for its use in clinical practice. Thus, we tested here a complete and reproducible evaluation of a new fully automatic software to characterize MV anatomy in different forms of mitral regurgitation (MR) by 3D TEE.Sixty patients were included: 45 with more than moderate MR (28 organic MR [OMR] and 17 functional MR [FMR]) and 15 controls...
December 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27930360/dcs-svm-a-novel-semi-automated-method-for-human-brain-mr-image-segmentation
#10
Ali Ahmadvand, Mohammad Reza Daliri, Mohammadtaghi Hajiali
In this paper, a novel method is proposed which appropriately segments magnetic resonance (MR) brain images into three main tissues. This paper proposes an extension of our previous work in which we suggested a combination of multiple classifiers (CMC)-based methods named dynamic classifier selection-dynamic local training local Tanimoto index (DCS-DLTLTI) for MR brain image segmentation into three main cerebral tissues. This idea is used here and a novel method is developed that tries to use more complex and accurate classifiers like support vector machine (SVM) in the ensemble...
December 8, 2016: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/27930308/epithelial-self-healing-is-recapitulated-by-a-3d-biomimetic-e-cadherin-junction
#11
Daniel J Cohen, Martijn Gloerich, W James Nelson
Epithelial monolayers undergo self-healing when wounded. During healing, cells collectively migrate into the wound site, and the converging tissue fronts collide and form a stable interface. To heal, migrating tissues must form cell-cell adhesions and reorganize from the front-rear polarity characteristic of cell migration to the apical-basal polarity of an epithelium. However, identifying the "stop signal" that induces colliding tissues to cease migrating and heal remains an open question. Epithelial cells form integrin-based adhesions to the basal extracellular matrix (ECM) and E-cadherin-mediated cell-cell adhesions on the orthogonal, lateral surfaces between cells...
December 5, 2016: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27929688/anatomical-location-differences-between-mutated-and-wild-type-isocitrate-dehydrogenase-1-in-low-grade-gliomas
#12
Jinhua Yu, Zhifeng Shi, Chunhong Ji, Yuxi Lian, Yuanyuan Wang, Liang Chen, Ying Mao
Anatomical location of gliomas has been considered as a factor implicating the contributions of a specific precursor cells during the tumor growth. Isocitrate dehydrogenase 1 (IDH1) is a pathognomonic biomarker with a significant impact on the development of gliomas and remarkable prognostic effect. The correlation between anatomical location of tumor and IDH1 states for low grade gliomas was analyzed quantitatively in this study. 92 patients diagnosed of low grade glioma pathologically were recruited in this study, including 65 patients with IDH1-mutated glioma and 27 patients with wide-type IDH1...
December 8, 2016: International Journal of Neuroscience
https://www.readbyqxmd.com/read/27929596/primary-solitary-intralabyrinthine-schwannoma-a-report-of-7-cases-and-a-review-of-the-literature
#13
Avi Shupak, Yehuda Holdstein, Margalit Kaminer, Itzhak Braverman
Intralabyrinthine schwannomas (ILSs) are uncommon benign tumors that originate in the Schwann cell sheath of the intralabyrinthine distal branches of the vestibulocochlear nerve. They have no initial involvement in the internal auditory canal, although that might develop later. These lesions can arise inside the cochlea, originate in the vestibule or, in rare cases, develop in the semicircular canals. From these sites, spread might take place via the anatomic connections between the perilymphatic spaces in the scala vestibuli and the anterior vestibule...
December 2016: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/27929512/a-survey-on-table-tolerances-and-couch-overrides-in-radiotherapy
#14
Bonnie Chinsky, Rakesh Patel, Joshua Panfil, Murat Surucu, John C Roeske
The purpose of this study was to survey current departmental policies on treatment couch overrides and the values of table tolerances used clinically. A 25-question electronic survey on couch overrides and tolerances was sent to full members of the American Association of Physicists in Medicine (AAPM). The first part of the survey asked participants if table overrides were allowed at their institution, who was allowed to perform these overrides, and if imaging was required with overrides. The second part of the survey asked individuals to provide table tolerance data for the following treatment sites: brain/head and neck (H&N), lung, breast, abdo-men/pelvis and prostate...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929508/development-of-a-universal-medical-x-ray-imaging-phantom-prototype
#15
Annemari Groenewald, Willem A Groenewald
Diagnostic X-ray imaging depends on the maintenance of image quality that allows for proper diagnosis of medical conditions. Maintenance of image quality requires quality assurance programs on the various X-ray modalities, which consist of pro-jection radiography (including mobile X-ray units), fluoroscopy, mammography, and computed tomography (CT) scanning. Currently a variety of modality-specific phantoms are used to perform quality assurance (QA) tests. These phantoms are not only expensive, but suitably trained personnel are needed to successfully use them and interpret the results...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929487/comparison-of-liver-volumetry-on-contrast-enhanced-ct-images-one-semiautomatic-and-two-automatic-approaches
#16
Wei Cai, Baochun He, Yingfang Fan, Chihua Fang, Fucang Jia
This study was to evaluate the accuracy, consistency, and efficiency of three liver volumetry methods- one interactive method, an in-house-developed 3D medical Image Analysis (3DMIA) system, one automatic active shape model (ASM)-based segmentation, and one automatic probabilistic atlas (PA)-guided segmentation method on clinical contrast-enhanced CT images. Forty-two datasets, including 27 normal liver and 15 space-occupying liver lesion patients, were retrospectively included in this study. The three methods - one semiautomatic 3DMIA, one automatic ASM-based, and one automatic PA-based liver volumetry - achieved an accuracy with VD (volume difference) of -1...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929485/difference-in-performance-between-3d-and-4d-cbct-for-lung-imaging-a-dose-and-image-quality-analysis
#17
Sheeba Thengumpallil, Kathleen Smith, Pascal Monnin, Jean Bourhis, François Bochud, Raphaël Moeckli
The study was to describe and to compare the performance of 3D and 4D CBCT imaging modalities by measuring and analyzing the delivered dose and the image quality. The 3D (Chest) and 4D (Symmetry) CBCT Elekta XVI lung IGRT protocols were analyzed. Dose profiles were measured with TLDs inside a dedicated phantom. The dosimetric indicator cone-beam dose index (CBDI) was evaluated. The image quality analysis was performed by assessing the contrast transfer function (CTF), the noise power spectrum (NPS) and the noise-equivalent quanta (NEQ)...
November 8, 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/27929457/advanced-animal-model-of-colorectal-metastasis-in-liver-imaging-techniques-and-properties-of-metastatic-clones
#18
Go Oshima, Melinda E Stack, Sean C Wightman, Darren Bryan, Elizabeth Poli, Lai Xue, Kinga B Skowron, Abhineet Uppal, Sean P Pitroda, Xiaona Huang, Mitchell C Posner, Samuel Hellman, Ralph R Weichselbaum, Nikolai N Khodarev
Patients with a limited number of hepatic metastases and slow rates of progression can be successfully treated with local treatment approaches(1,2). However, little is known about the heterogeneity of liver metastases, and animal models capable of evaluating the development of individual metastatic colonies are needed. Here, we present an advanced model of hepatic metastases that provides the ability to quantitatively visualize the development of individual tumor clones in the liver and estimate their growth kinetics and colonization efficiency...
November 30, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27929156/correlation-of-annealing-time-with-crystal-structure-composition-and-electronic-properties-of-ch3nh3pbi3-xclx-mixed-halide-perovskite-films
#19
Maryline Ralaiarisoa, Yan Busby, Johannes Frisch, Ingo Salzmann, Jean-Jacques Pireaux, Norbert Koch
Using 3D imaging with time-of-flight secondary ion mass spectrometry (ToF-SIMS) complemented by grazing-incidence X-ray diffraction (GIXRD), we spatially resolve changes in both the composition and structure of CH3NH3I3-xClx perovskite films on conducting polymer substrates at different annealing stages, in particular, before and after complete perovskite crystallization. The early stage of annealing is characterized by phase separation throughout the entire film into domains with perovskite and domains with a dominating chloride-rich phase...
December 8, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27928834/fast-fourier-based-simulation-of-off-resonance-artifacts-in-steady-state-gradient-echo-mri-applied-to-metal-object-localization
#20
Frank Zijlstra, Job G Bouwman, Ieva Braškutė, Max A Viergever, Peter R Seevinck
PURPOSE: To accelerate simulation of off-resonance artifacts in steady-state gradient echo MRI by using fast Fourier transforms and demonstrate its applicability to metal object localization. THEORY AND METHODS: By exploiting the repetitive nature of steady-state pulse sequences it is possible to use fast Fourier transforms to calculate the MR signal. Based on this principle, a method for fast simulation of off-resonance artifacts was designed. The method was validated against Bloch simulations and MRI scans...
December 7, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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