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https://www.readbyqxmd.com/read/29909085/essential-steps-in-bioprinting-from-pre-to-post-bioprinting
#1
REVIEW
Pallab Datta, Ananya Barui, Yang Wu, Veli Ozbolat, Kazim K Moncal, Ibrahim T Ozbolat
An increasing demand for directed assembly of biomaterials has inspired the development of bioprinting, which facilitates the assembling of both cellular and acellular inks into well-arranged three-dimensional (3D) structures for tissue fabrication. Although great advances have been achieved in the recent decade, there still exist issues to be addressed. Herein, a review has been systematically performed to discuss the considerations in the entire procedure of bioprinting. Though bioprinting is advancing at a rapid pace, it is seen that the whole process of obtaining tissue constructs from this technique involves multiple-stages, cutting across various technology domains...
June 14, 2018: Biotechnology Advances
https://www.readbyqxmd.com/read/29909060/quantification-of-bone-microstructure-in-the-wrist-using-cone-beam-computed-tomography
#2
Karen Mys, Filip Stockmans, Evie Vereecke, G Harry van Lenthe
Due to the rising life expectancy, bone diseases (e.g. osteoporosis, osteoarthritis) and trauma (e.g. fracture) have become an important socio-economic burden. Accurate visualization and quantification of the bone microstructure in vivo is seen as an important step to enhance diagnosis and treatment. Micro-computed tomography (microCT) has become the gold standard in three-dimensional (3D) imaging of trabecular bone structure. Yet, usage is limited to ex vivo analyses, hence, it cannot be used to evaluate bone and bone adaptive responses in a patient...
June 14, 2018: Bone
https://www.readbyqxmd.com/read/29908789/first-experience-with-markerless-online-3d-spine-position-monitoring-during-sbrt-delivery-using-a-conventional-linac
#3
Colien Hazelaar, Wilko F A R Verbakel, Hassan Mostafavi, Lineke van der Weide, Ben J Slotman, Max Dahele
PURPOSE: The purpose was to report our initial experience with online markerless 3-dimensional (3D) spine position monitoring. We used template matching plus triangulation of fluoroscopic kilovoltage images acquired with the gantry-mounted imager during flattening filter-free volumetric modulated arc spine stereotactic body radiation therapy delivery on a conventional linear accelerator. METHODS AND MATERIALS: Kilovoltage images were acquired at 7 frames per second and streamed to a stand-alone computer...
April 22, 2018: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29908724/three-dimensional-inferior-vena-cava-for-assessing-central-venous-pressure-in-patients-with-cardiogenic-shock
#4
Raphaëlle Huguet, Damien Fard, Thomas d'Humieres, Ophelie Brault-Meslin, Laureline Faivre, Louis Nahory, Jean-Luc Dubois-Randé, Julien Ternacle, Leopold Oliver, Pascal Lim
BACKGROUND: The inferior vena cava (IVC) has a complex three-dimensional (3D) shape, but measurements used to estimate central venous pressure (CVP) remain based on two-dimensional (2D) echocardiographic imaging. The aim of this study was to investigate the accuracy of IVC size and collapsibility index obtained by 3D echocardiography for assessing CVP in patients with cardiogenic shock. METHODS: Eighty consecutive echocardiographic examinations performed in 33 patients (mean age, 72 ± 15 years; mean left ventricular ejection fraction, 19 ± 10%) admitted for cardiogenic shock were prospectively included...
June 13, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29908655/analysis-of-surface-to-surface-distance-mapping-during-three-dimensional-motion-at-the-ankle-and-subtalar-joints
#5
Sorin Siegler, Tobias Konow, Claudio Belvedere, Andrea Ensini, Rewati Kulkarni, Alberto Leardini
Joint surface interaction and ligament constraints determine the kinematic characteristics of the ankle and subtalar joints. Joint surface interaction is characterized by joint contact mechanics and by relative joint surface position potentially characterized by distance mapping. While ankle contact mechanics was investigated, limited information is available on joint distance mapping and its changes during motion. The purpose of this study was to use image-based distance mapping to quantify this interaction at the ankle and subtalar joints during tri-planar rotations of the ankle complex...
June 7, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29907931/influence-of-2d-vs-3d-imaging-and-professional-experience-on-dental-implant-treatment-planning
#6
João Henrique Fortes, Christiano de Oliveira-Santos, Wilson Matsumoto, Raphael Jurca Gonçalves da Motta, Camila Tirapelli
OBJECTIVES: This study investigated whether professional experience and type of image examination (panoramic radiography (PAN) or cone beam computed tomography (CBCT)) could influence the pre-surgical planning for dental implant treatment. MATERIALS AND METHODS: Six dentists, from two different levels of experience (senior (Sr) and junior (Jr)) performed simulated pre-surgical planning by using PANs and after 1 month, by using CBCTs, considering implant length (IL), implant width (IW), need for bone graft (BG), and other surgical procedures (OP)...
June 16, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29907828/super-resolution-three-dimensional-fluorescence-and-optical-diffraction-tomography-of-live-cells-using-structured-illumination-generated-by-a-digital-micromirror-device
#7
Seungwoo Shin, Doyeon Kim, Kyoohyun Kim, YongKeun Park
We present a multimodal approach for measuring the three-dimensional (3D) refractive index (RI) and fluorescence distributions of live cells by combining optical diffraction tomography (ODT) and 3D structured illumination microscopy (SIM). A digital micromirror device is utilized to generate structured illumination patterns for both ODT and SIM, which enables fast and stable measurements. To verify its feasibility and applicability, the proposed method is used to measure the 3D RI distribution and 3D fluorescence image of various samples, including a cluster of fluorescent beads, and the time-lapse 3D RI dynamics of fluorescent beads inside a HeLa cell, from which the trajectory of the beads in the HeLa cell is analyzed using spatiotemporal correlations...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907748/extracellular-nanovesicles-released-from-the-commensal-yeast-malassezia-sympodialis-are-enriched-in-allergens-and-interact-with-cells-in-human-skin
#8
Henrik J Johansson, Helen Vallhov, Tina Holm, Ulf Gehrmann, Anna Andersson, Catharina Johansson, Hans Blom, Marta Carroni, Janne Lehtiö, Annika Scheynius
Malassezia sympodialis is a dominant commensal fungi in the human skin mycobiome but is also associated with common skin disorders including atopic eczema (AE). M. sympodialis releases extracellular vesicles, designated MalaEx, which are carriers of small RNAs and allergens, and they can induce inflammatory cytokine responses. Here we explored how MalaEx are involved in host-microbe interactions by comparing protein content of MalaEx with that of the parental yeast cells, and by investigating interactions of MalaEx with cells in the skin...
June 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29907740/single-breath-hold-photoacoustic-computed-tomography-of-the-breast
#9
Li Lin, Peng Hu, Junhui Shi, Catherine M Appleton, Konstantin Maslov, Lei Li, Ruiying Zhang, Lihong V Wang
We have developed a single-breath-hold photoacoustic computed tomography (SBH-PACT) system to reveal detailed angiographic structures in human breasts. SBH-PACT features a deep penetration depth (4 cm in vivo) with high spatial and temporal resolutions (255 µm in-plane resolution and a 10 Hz 2D frame rate). By scanning the entire breast within a single breath hold (~15 s), a volumetric image can be acquired and subsequently reconstructed utilizing 3D back-projection with negligible breathing-induced motion artifacts...
June 15, 2018: Nature Communications
https://www.readbyqxmd.com/read/29906672/displacement-of-teeth-without-and-with-bonded-fixed-orthodontic-retainers-3d-analysis-using-triangular-target-frames-and-optoelectronic-motion-tracking-device
#10
Firas Chakroun, Vera Colombo, Dave Lie Sam Foek, Luigi Maria Gallo, Albert Feilzer, Mutlu Özcan
PURPOSE: The objective of this study was to evaluate the anterior tooth movement without and with bonded fixed orthodontic retainers under incremental loading conditions. MATERIALS AND METHODS: Six extracted mandibular anterior human teeth were embedded in acrylic resin in True Form I Arch type and 3D reconstruction of Digital Volume Tomography (DVT) images (0.4 mm3 voxels) were obtained. The anatomy of each tooth was segmented and digitally reconstructed using 3D visualization software for medical images (AMIRA, FEI SVG)...
June 6, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29906289/activation-recovery-interval-imaging-of-premature-ventricular-contraction
#11
Ting Yang, Long Yu, Qi Jin, Liqun Wu, Bin He
Dispersion of ventricular repolarization due to abnormal activation contributes to the susceptibility to cardiac arrhythmias. However, the global pattern of repolarization is difficult to assess clinically. Activation recovery interval (ARI) has been used to understand the properties of ventricular repolarization. In this study, we developed an ARI imaging technique to noninvasively reconstruct three-dimensional (3D) ARI maps in 10 premature ventricular contraction (PVC) patients and evaluated the results with the endocardial ARI maps recorded by a clinical navigation system (CARTO)...
2018: PloS One
https://www.readbyqxmd.com/read/29906086/biofouling-resistant-platinum-bimetallic-alloys
#12
Ahmed A Farghaly, Rezaul K Khan, Maryanne M Collinson
A new electrosynthetic approach for the fabrication of three-dimensional bicontinuous nanoporous platinum-based (3D-BC-NP-Pt(Au)) electrodes is described. Binary Pt-Ag alloys are first electrodeposited on gold substrates from appropriately formulated plating solutions. Following annealing and dealloying, a new family of nanoporous platinum-based electrodes emerges whose morphology, porosity, and chemical compositions depend on electrodeposition parameters and plating solution composition. Scanning electron microscopy images reveal an interesting and distinctive nanoporous gold-like microstructure with pores and ligaments in the 10-30 nm range arranged in a bicontinuous fashion throughout the thickness of the film...
June 15, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29905734/two-color-volumetric-laser-induced-fluorescence-for-3d-oh-and-temperature-fields-in-turbulent-reacting-flows
#13
B R Halls, P S Hsu, S Roy, T R Meyer, J R Gord
Single-shot, two-color, volumetric laser-induced fluorescence was demonstrated for three-dimensional (3D), tomographic imaging of the structural properties of the OH radical and temperature field in a turbulent hydrogen-air flame. Two narrowband laser sources were tuned to the Q1 (5) and Q1 (14) transitions of the (1,0) band in the A2 Σ←X2 Π system and illuminated a volumetric region of the flame. Images from eight unique perspectives collected simultaneously from each of the two transitions were used to reconstruct overlapping OH fields with different Boltzmann fractions and map the 3D temperature distribution with nanosecond precision...
June 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29905730/bubbles-drops-and-solid-particles-recognition-from-real-or-virtual-photonic-jets-reconstructed-by-digital-in-line-holography
#14
Matthias P L Sentis, Fabrice R A Onofri, Fabrice Lamadie
The image of the photonic jet (also called caustic) formed by a large, transparent, and spherical particle, reconstructed by digital in-line holography, is shown to be similar to the Airy pattern observed at the focus of a diffraction-limited lens. The analysis of this image, real or virtual depending on whether the particle relative refractive index is above or below one, allows characterizing the particle composition via its refractive index. Experiments clearly demonstrate the value of this method for the simultaneous 3D characterization and differentiation of the dynamics, size, and composition of gas, liquid, and solid particles in multiphase flows...
June 15, 2018: Optics Letters
https://www.readbyqxmd.com/read/29904646/spatial-relationship-between-bone-formation-and-mechanical-stimulus-within-cortical-bone-combining-3d-fluorochrome-mapping-and-poroelastic-finite-element-modelling
#15
A Carrieroa, A F Pereirab, A J Wilson, S Castagno, B Javaheri, A A Pitsillides, M Marenzana, S J Shefelbine
Bone is a dynamic tissue and adapts its architecture in response to biological and mechanical factors. Here we investigate how cortical bone formation is spatially controlled by the local mechanical environment in the murine tibia axial loading model (C57BL/6). We obtained 3D locations of new bone formation by performing 'slice and view' 3D fluorochrome mapping of the entire bone and compared these sites with the regions of high fluid velocity or strain energy density estimated using a finite element model, validated with ex-vivo bone surface strain map acquired ex-vivo using digital image correlation...
June 2018: Bone Reports
https://www.readbyqxmd.com/read/29904280/incorporation-of-ddr2-clusters-into-collagen-matrix-via-integrin-dependent-posterior-remnant-tethering
#16
Tingting Li, Jin'e Liu, Hao Cai, Baomei Wang, Yunfeng Feng, Jun Liu
Cell-matrix interactions play critical roles in cell adhesion, tissue remodeling and cancer metastasis. Discoidin domain receptor 2 (DDR2) is a collagen receptor belonging to receptor tyrosine kinase (RTK) family. It is a powerful regulator of collagen deposition in the extracellular matrix (ECM). Although the oligomerization of DDR extracellular domain (ECD) proteins can affect matrix remodeling by inhibiting fibrillogenesis, it is still unknown how cellular DDR2 is incorporated into collagen matrix. Using 3-dimentional (3D) imaging for migrating cells, we identified a novel mechanism that explains how DDR2 incorporating into collagen matrix, which we named as posterior remnant tethering...
2018: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/29903557/3d-volume-rendering-and-3d-printing-additive-manufacturing
#17
REVIEW
Rujuta A Katkar, Robert M Taft, Gerald T Grant
Three-dimensional (3D) volume-rendered images allow 3D insight into the anatomy, facilitating surgical treatment planning and teaching. 3D printing, additive manufacturing, and rapid prototyping techniques are being used with satisfactory accuracy, mostly for diagnosis and surgical planning, followed by direct manufacture of implantable devices. The major limitation is the time and money spent generating 3D objects. Printer type, material, and build thickness are known to influence the accuracy of printed models...
July 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29903556/cone-beam-computed-tomography
#18
REVIEW
Ibrahim Nasseh, Wisam Al-Rawi
In the last several decades, the need for 3D images in dentistry have developed. Computerized tomography was first introduced mainly with the advent of implantology, but its use remained limited to a small number of specialists, due to its indications, access and dose radiation. In the late 90's, a new technology using a cone-shaped beam and a reciprocating detector, which rotates around the patient 360 degrees and acquires projected data in a single rotation, namely the cone beam computerized tomography (CBCT), invaded dentistry, making the perception of 3D easily acceptable to dentists and their patients...
July 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29903498/betti-number-ratios-as-quantitative-indices-for-bone-morphometry-in-three-dimensions
#19
Takashi Teramoto, Takeshi Kamiya, Taira Sakurai, Fuminori Kanaya
BACKGROUND AND OBJECTIVE: Computational homology is an emerging mathematical tool for characterizing shapes of data. In this work, we present a methodology using computational homology for obtaining quantitative measurements of the connectivity in bone morphometry. We introduce the Betti number ratios as novel morphological descriptor for the classification of bone fine structures in three dimensions. METHODS: A total of 51 Japanese white rabbits were used to investigate the connectivity of bone trabeculae after the administration of alendronate in a tendon graft model in rabbits...
August 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29903442/probing-the-neuroanatomy-of-the-cerebellum-using-tractography
#20
Christophe Habas, Mario Manto
Diffusion tensor imaging (DTI) is a noninvasive neuroimaging tool assessing the organization of white-matter tracts and brain microstructure in vivo. The technique takes into account the three-dimensional (3D) direction of diffusion of water in space, the brownian movements of water being constrained by the brain microstructure. The main direction of diffusion in the brain is extracted to obtain the principal direction of axonal projection within a given voxel. Overall, the diffusion tensor is a mathematic analysis of the magnitude/directionality (anisotropy) of the movement of water molecules in 3D space...
2018: Handbook of Clinical Neurology
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