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Calcium gluconate

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https://www.readbyqxmd.com/read/27891040/inadvertent-injection-of-potassium-chloride-instead-of-sodium-chloride-during-treatment-of-chronic-low-back-ache-with-epidural-injection-leading-to-paraplegia
#1
Rahul Ranjan, Naiyer Asif, Sohail Ahmad, Syed Ifthekar
Epidural injection of steroid is given for back pain resistant to other conservative management. Normal saline (NS) is used as diluent in 80 mg methylprednisolone and a local anesthetic. Due to a similar looking ampoule of NS and potassium chloride (KCl), there is a probability of accidental use of KCl instead of NS. We present a case of a 50-year-old male patient having low back ache refractory to other conservative treatments. Epidural injection of steroid was given, but accidently KCl was mixed with methylprednisolone instead of NS...
October 2016: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/27849108/influence-of-calcium-salts-and-bovine-thrombin-on-growth-factor-release-from-equine-platelet-rich-gel-supernatants
#2
Carlos E Giraldo, María E Álvarez, Jorge U Carmona
OBJECTIVE: To compare five activation methods in equine platelet-rich plasma (PRP) by determination of platelet-derived growth factor BB (PDGF-BB) and transforming growth factor beta 1 (TGF-β1) concentrations in platelet-rich gel (PRG) supernatants. METHODS: Platelet-rich plasma from 20 horses was activated by calcium chloride (CC), calcium gluconate (CG), bovine thrombin (BT), and their combinations, BTCC and BTCG. Both growth factor concentrations in PRG supernatants were measured by ELISA and compared with plasma and platelet lysates (PL) over time...
November 16, 2016: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/27817746/national-study-on-the-adequacy-of-antidotes-stocking-in-lebanese-hospitals-providing-emergency-care
#3
Anthony Mansour, Layla Al-Bizri, Jad El-Maamary, Amanda Al-Helou, Rayan Hamade, Elie Saliba, Dina Khammash, Karim Makhoul, Kamal Matli, Nada Ghosn, Mary Deeb, Wissam H Faour
BACKGROUND: Antidotes stocking is a critical component of hospital care for poisoned patients in emergency. Antidote stocking represents a major health challenge worldwide and in Lebanon. Systematic data monitoring of antidote stocking in Lebanese hospitals is lacking. The objective of this study is to assess the adequacy of antidotes stocking in Lebanese hospitals according to type and quantity and explore the characteristics associated with their differential availability. METHODS: Data collection to assess antidote availability and its correlate was undertaken through a self-administered questionnaire...
November 7, 2016: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/27801462/calcium-complexation-and-acid-base-properties-of-l-gulonate-a-diastereomer-of-d-gluconate
#4
Bence Kutus, Ákos Buckó, Gábor Peintler, István Pálinkó, Pál Sipos
The Ca(ii)-complexation and acid-base properties of l-gulonic acid (HGul), a diastereomer of d-gluconic acid (HGluc) differing only in the configurations of C2 and C5 have been investigated via(1)H and (13)C NMR spectroscopies, Ca-ISE- and pH-potentiometry, polarimetry and freezing point depression. Data obtained for Gul(-)/HGul have been compared with those of Gluc(-)/HGluc. It was found that some properties (acid dissociation constant, the stoichiometry and formation constants of the Ca(ii)-complexes) were insensitive to the difference in the configuration...
November 1, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27782747/three-types-of-ion-channels-in-the-cell-membrane-of-mouse-fibroblasts
#5
M Koselski, A Olszewska, A Hordyjewska, T Małecka-Massalska, K Trebacz
Patch clamp recordings carried out in the inside-out configuration revealed activity of three kinds of channels: nonselective cation channels, small-conductance K(+) channels, and large-conductance anion channels. The nonselective cation channels did not distinguish between Na(+) and K(+). The unitary conductance of these channels reached 28 pS in a symmetrical concentration of 200 mM NaCl. A lower value of this parameter was recorded for the small-conductance K(+) channels and in a 50-fold gradient of K(+) (200 mM/4 mM) it reached 8 pS...
October 26, 2016: Physiological Research
https://www.readbyqxmd.com/read/27769972/physical-compatibility-of-tedizolid-phosphate-with-selected-i-v-drugs-during-simulated-y-site-administration
#6
Islam Ghazi, Yukihiro Hamada, David P Nicolau
PURPOSE: The physical compatibility of commonly used agents that could be coadministered in the clinical setting with tedizolid phosphate during Y-site administration was evaluated. METHODS: Tedizolid phosphate vials were reconstituted to a final concentration of 0.8 mg/mL. All other drugs were prepared according to manufacturers' recommendations and diluted with 0.9% sodium chloride injection (where applicable) to the highest standard concentrations used clinically...
November 1, 2016: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/27765663/comprehensive-technical-and-patient-care-optimization-in-the-management-of-pediatric-apheresis-for-peripheral-blood-stem-cell-harvesting
#7
Yoshihiro Ohara, Hitoshi Ohto, Tetsunori Tasaki, Hideki Sano, Kazuhiro Mochizuki, Mitsuko Akaihata, Shogo Kobayashi, Tomoko Waragai, Masaki Ito, Mitsuaki Hosoya, Kenneth E Nollet, Kazuhiko Ikeda, Chitose Ogawa, Takahiro Kanno, Yayoi Shikama, Atsushi Kikuta
BACKGROUND: Pediatric apheresis for peripheral blood stem cell transplantation should be carried out with due concern for low corporeal blood volume and vulnerability to hypocalcemia-related complications, hypovolemic shock, and hypervolemic cardiac overload. STUDY DESIGN AND METHODS: We retrospectively investigated a total of 267 apheresis procedures from 1990 to 2013 on 93 children between 0 and 10 years old, including 89 patients and 4 healthy donors, with body weights of 6...
September 30, 2016: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/27746647/hydrofluoric-acid-burn-on-a-fingertip-treated-successfully-with-single-session-of-subcutaneous-injection-of-6-7-calcium-gluconate
#8
So Eun Park, Jin Yong Lee, Chul Woo Kim, Sang Seok Kim
No abstract text is available yet for this article.
October 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27732742/calcium-administration-is-associated-with-adverse-outcomes-in-critically-ill-patients-receiving-parenteral-nutrition-results-from-a-natural-experiment-created-by-a-calcium-gluconate-shortage
#9
Bryan Dotson, Patrick Larabell, Jasmine U Patel, Kristoffer Wong, Lina Qasem, William Arthur, Chaim Leiberman, Peter Whittaker, Steven D Tennenberg
STUDY OBJECTIVE: Parenteral calcium is frequently administered to critically ill patients. However, animal studies demonstrate that calcium administration during critical illness heightens inflammation and leads to shock, organ dysfunction, and mortality. We sought to evaluate the association between calcium administration and adverse outcomes in critically ill patients receiving parenteral nutrition (PN). DESIGN: Retrospective cohort examined before and during a calcium gluconate shortage...
October 12, 2016: Pharmacotherapy
https://www.readbyqxmd.com/read/27726423/plantar-fasciitis-a-comparison-of-treatment-with-intralesional-steroids-versus-platelet-rich-plasma-prp-a-randomized-blinded-study
#10
Carlos Acosta-Olivo, Jorge Elizondo-Rodriguez, Ricardo Lopez-Cavazos, Felix Vilchez-Cavazos, Mario Simental-Mendia, Oscar Mendoza-Lemus
BACKGROUND: Many treatment options for plantar fasciitis currently exist, some with great success in pain relief. The objective of our study was to compare the use of intralesional steroids with platelet-rich plasma (PRP), using pain scales and functional evaluation, in patients with plantar fasciitis who did not respond to conservative treatment. METHODS: A controlled, randomized, blinded clinical assay was performed. Patients were assigned to one of the two groups by selecting a sealed envelope...
October 11, 2016: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/27701127/efficacy-and-safety-of-a-novel-autologous-wound-matrix-in-the-management-of-complicated-chronic-wounds-a-pilot-study
#11
Igal Kushnir, Alon Kushnir, Thomas E Serena, Doron Garfinkel
INTRODUCTION: The objective of this pilot study was to evaluate the efficacy and safety of a novel method using an autologous whole blood clot formed with the RedDress Wound Care System (RD1, RedDress Ltd, Israel), a provisional whole blood clot matrix used in the treatment of chronic wounds of various etiologies. METHODS AND MATERIALS: Patients were treated at the bedside with the whole blood clot matrix. Blood was withdrawn from each patient using citrate, mixed with a calcium gluconate/kaolin suspension, and injected into an RD1 clotting tray...
September 2016: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/27679526/aluminum-content-of-neonatal-parenteral-nutrition-solutions-options-for-reducing-aluminum-exposure
#12
Robert K Huston, Carl F Heisel, Benjamin R Vermillion, J Mark Christensen, Leah Minc
INTRODUCTION: Calcium chloride (CaCl2) has been the only calcium additive available in the United States that has a low aluminum (Al) content. Calcium gluconate in glass vials (CaGluc-Gl) has a high Al content while calcium gluconate in plastic vials (CaGluc-Pl) has a low Al content. The purpose of this study was to measure Al concentrations in neonatal parenteral nutrition (PN) solutions prepared using various calcium additives. METHODS: Samples of solutions compounded with CaCl2 or CaGluc-Gl and sodium phosphate (NaPhos) as well as CaGluc-Pl and sodium glycerophosphate (NaGP) with and without cysteine were analyzed for Al content...
September 27, 2016: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/27650188/importance-of-initial-management-and-surgical-treatment-after-hydrofluoric-acid-burn-of-the-finger
#13
Hyun Ho Han, Byung Yeun Kwon, Sung No Jung, Suk-Ho Moon
Occupational injuries to digits due to hydrofluoric acid (HFA) are frequently encountered. They have distinctive features, including intense pain, progressive tissue necrosis, and possible bone erosion. To minimize tissue damage, it is of great importance to execute prudent preoperative assessment and determine the correct surgical modality to reconstruct and maintain the function of the hand. However, proper protocols for fingers have not been presented in previous studies. Eight cases with HFA burn to digits were presented to the emergency room...
September 17, 2016: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/27611484/enhancement-of-ocular-in-situ-gelling-properties-of-low-acyl-gellan-gum-by-use-of-ion-exchange
#14
Kenneth Reed, Amy Li, Britney Wilson, Tetchi Assamoi
PURPOSE: The purpose of this study was to determine if the addition of calcium gluconate to gellan solution results in a stronger gel structure on initial exposure to tear fluid due to the displacement of calcium from the gluconate ion by tear monovalent cations (Na(+), K(+)). METHODS: Test solutions of gellan and gellan-calcium gluconate were mixed thoroughly with simulated tear fluid (STF) at a 5:1 ratio. The resulting gel was measured for viscosity at 32°C-36°C...
September 9, 2016: Journal of Ocular Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/27609122/prolonged-hypocalcemia-refractory-to-calcium-gluconate-after-ammonium-bifluoride-ingestion-in-a-pediatric-patient
#15
Joseph K Maddry, Avery Kester, Kennon Heard
No abstract text is available yet for this article.
August 18, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27510531/intracellular-calcium-increases-in-vascular-smooth-muscle-cells-with-progression-of-chronic-kidney-disease-in-a-rat-model
#16
Stacey Dineen Rodenbeck, Chad A Zarse, Mikaela L McKenney-Drake, Rebecca S Bruning, Michael Sturek, Neal X Chen, Sharon M Moe
BACKGROUND: Vascular smooth muscle cells (VSMCs) exhibit phenotypic plasticity, promoting vascular calcification and increasing cardiovascular risk. Changes in VSMC intracellular calcium ([Ca(2+)]i) are a major determinant of plasticity, but little is known about changes in [Ca(2+)]i in chronic kidney disease (CKD). We have previously demonstrated such plasticity in aortas from our rat model of CKD and therefore sought to examine changes in [Ca(2+)]i during CKD progression. MATERIALS AND METHODS: We examined freshly isolated VSMCs from aortas of normal rats, Cy/+ rats (CKD) with early and advanced CKD, and advanced CKD rats treated without and with 3% calcium gluconate (CKD + Ca(2+)) to lower parathyroid hormone (PTH) levels...
August 9, 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27425865/molecular-cloning-and-sequence-analysis-of-a-pvgox-gene-encoding-glucose-oxidase-in-penicillium-viticola-f1-strain-and-it-s-expression-quantitation
#17
Ibrar Khan, Sadia Qayyum, Shehzad Ahmed, Zeeshan Niaz, Nighat Fatima, Zhen-Ming Chi
The PVGOX gene (accession number: KT452630) was isolated from genomic DNA of the marine fungi Penicillium viticola F1 by Genome Walking and their expression analysis was done by Fluorescent RT-PCR. An open reading frame of 1806bp encoding a 601 amino acid protein (isoelectric point: 5.01) with a calculated molecular weight of 65,535.4 was characterized. The deduced protein showed 75%, 71%, 69% and 64% identity to those deduced from the glucose oxidase (GOX) genes from different fungal strains including; Talaromyces variabilis, Beauveria bassiana, Aspergillus terreus, and Aspergillus niger, respectively...
November 5, 2016: Gene
https://www.readbyqxmd.com/read/27424021/hydroxyethyl-starch-could-save-a-patient-with-acute-aluminum-phosphide-poisoning
#18
Sayed Mahdi Marashi, Zeynab Nasri Nasrabadi, Mostafa Jafarzadeh, Sogand Mohammadi
A 40-year-old male patient with suicidal ingestion of one tablet of aluminium phosphide was referred to the department of toxicology emergency of Baharloo Hospital, Tehran, Iran. The garlic odor was smelled from the patient and abdominal pain and continuous vomiting as well as agitation and heartburn were the first signs and symptoms. Systolic and diastolic blood pressures at the arrival time were 95 and 67 mmHg, respectively. Gastric lavage with potassium permanganate (1:10,000), and 2 vials of sodium bicarbonate through a nasogastric tube was started for the patient and the management was continued with free intravenous infusion of 1 liter of NaCl 0...
July 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/27411455/determinants-of-calcium-infusion-rate-during-continuous-veno-venous-hemofiltration-with-regional-citrate-anticoagulation-in-critically-ill-patients-with-acute-kidney-injury
#19
De-Lin Liu, Li-Feng Huang, Wen-Liang Ma, Qi Ding, Yue Han, Yue Zheng, Wen-Xiong Li
BACKGROUND: It is unclear that how to decide the calcium infusion rate during continuous veno-venous hemofiltration (CVVH) with regional citrate anticoagulation (RCA). This study aimed to assess the determinants of calcium infusion rate during CVVH with RCA in critically ill patients with acute kidney injury (AKI). METHODS: A total of 18 patients with AKI requiring CVVH were prospectively analyzed. Postdilution CVVH was performed with a fixed blood flow rate of 150 ml/min and a replacement fluid flow rate of 2000 ml/h for each new circuit...
July 20, 2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27397996/in-vitro-study-of-the-role-of-thrombin-in-platelet-rich-plasma-prp-preparation-utility-for-gel-formation-and-impact-in-growth-factors-release
#20
Stephany Cares Huber, José Luiz Rosenberis Cunha Júnior, Silmara Montalvão, Letícia Queiroz da Silva, Aline Urban Paffaro, Francesca Aparecida Ramos da Silva, Bruno Lima Rodrigues, José Fabio Santos Duarte Lana, Joyce Maria Annichino-Bizzacchi
INTRODUCTION: The use of PRP has been studied for different fields, with promising results in regenerative medicine. Until now, there is no study in the literature evaluating thrombin levels in serum, used as autologous thrombin preparation. Therefore, in the present study we evaluated the role played by different thrombin concentrations in PRP and the impact in the release of growth factors. Also, different activators for PRP gel formation were evaluated. METHODS: Thrombin levels were measured in different autologous preparations: serum, L-PRP (PRP rich in leukocytes) and T-PRP (thrombin produced through PRP added calcium gluconate)...
2016: Journal of Stem Cells & Regenerative Medicine
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