keyword
https://read.qxmd.com/read/38526213/recommended-ten-years-follow-up-strategy-for-small-hepatocellular-carcinoma-after-radiofrequency-ablation-a-cost-effectiveness-evaluation
#21
JOURNAL ARTICLE
Qi-Feng Chen, Song Chen, Jun-Zhe Yi, Jiong-Liang Wang, Sui-Xing Zhong, Xiong-Ying Jiang, Yue Hu, Gen-Jun Tan, Jie Xu, Ning Lyu, Ming Zhao
OBJECTIVES: An optimal follow-up schedule for small (≤3 cm) hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA) remains unclear in clinical guidelines. We aimed to assess the cost-effectiveness of follow-up strategies in patients with small HCC after RFA. METHODS: In total, 11,243 patients were collected from global institutions to calculate recurrence rates. Subsequently, a Markov model covering a 10-year period was developed to compare 25 surveillance strategies involving different surveillance techniques (computed tomography [CT], magnetic resonance imaging or ultrasonography [US] and alpha-fetoprotein [AFP]) and intervals (3 or 6 months)...
March 25, 2024: American Journal of Gastroenterology
https://read.qxmd.com/read/38526038/medication-non-adherence-and-predictor-factors-among-adult-asthmatic-patients-in-ethiopia-a-systematic-review-and-meta-analysis
#22
REVIEW
Chernet Tafere, Bereket Bahiru, Adane Yehualaw, Desalegn Getnet Demsie, Kebede Feyisa, Malede Berihun Yismaw, Endalamaw Aschale, Zenaw Debasu, Zewdu Yilma, Zegaye Agmassie, Sileshi Mulatu, Yazachew Engida Yismaw, Ousman Adal, Destaw Endeshaw
Objective: A pronounced burden is evident in individuals with asthma, with approximately half of them not adhering to their prescribed medication. Therefore this study aimed to assess the pooled prevalence of anti-asthma medications non-adherence in Ethiopia. Data sources: A comprehensive search was conducted across multiple electronic databases including PubMed, Africa Index Medicus, Science Direct, Hinari, and a search engine, Google Scholar from October 5 to 20, 2023. In addition, digital research repositories from Addis Ababa and Bahir Dar University were accessed...
March 25, 2024: Journal of Asthma
https://read.qxmd.com/read/38525272/predictive-nomogram-for-lymph-node-metastasis-and-survival-in-gastric-cancer-using-contrast-enhanced-computed-tomography-based-radiomics-a-retrospective-study
#23
JOURNAL ARTICLE
Weiteng Zhang, Sujun Wang, Qiantong Dong, Wenjing Chen, Pengfei Wang, Guanbao Zhu, Xiaolei Chen, Yiqi Cai
BACKGROUND: Lymph node involvement significantly impacts the survival of gastric cancer patients and is a crucial factor in determining the appropriate treatment. This study aimed to evaluate the potential of enhanced computed tomography (CT)-based radiomics in predicting lymph node metastasis (LNM) and survival in patients with gastric cancer before surgery. METHODS: Retrospective analysis of clinical data from 192 patients diagnosed with gastric carcinoma was conducted...
2024: PeerJ
https://read.qxmd.com/read/38524003/an-unusual-and-protracted-course-of-a-haggitt-3-malignant-polyp-recurrence
#24
Pratik Raichurkar, Tae Jun Kim, Christopher Byrne
Timely detection of colorectal cancer recurrence is paramount, as treatment of early-stage recurrence greatly improves survival and outcomes. Current guidelines outline post-resection surveillance through endoscopy, CT imaging, and tumor markers for five years; however, there is minimal data to guide follow-up beyond this. We present the case of a 60-year-old female with locoregional recurrence 15 years after endoscopic mucosal resection of a low-grade Haggit level 3 sigmoid colon polyp. Unusually the recurrence was noted as an incidental finding following investigation of an elevated alpha-fetoprotein level post liver transplant, and a retrospective review of imaging revealed a calcified sigmoid mesentery mass...
February 2024: Curēus
https://read.qxmd.com/read/38523058/hormone-replacement-therapy-and-periodontitis-progression-in-postmenopausal-women-a-prospective-cohort-study
#25
JOURNAL ARTICLE
Ying Man, Cui Zhang, Cheng Cheng, Laiqi Yan, Min Zong, Feifei Niu
OBJECTIVE: This study aimed to investigate the responses of periodontal environment to hormone replacement therapy (HRT) in postmenopausal women with or without periodontitis. BACKGROUND: HRT is a common and effective strategy for controlling menopausal symptoms, while the changes of periodontal environment under it, particularly in postmenopausal women with periodontitis, remain unclear. METHODS: As a prospective cohort study, a total of 97 postmenopausal women receiving HRT were screened, including 47 with and 50 without periodontitis...
March 24, 2024: Journal of Periodontal Research
https://read.qxmd.com/read/38522980/patient-provider-lung-cancer-screening-discussions-an-analysis-of-a-national-survey
#26
JOURNAL ARTICLE
Niki Nourmohammadi, Trinity Hsiao Pei Liang, Gelareh Sadigh
BACKGROUND: The US Preventative Service Task Force (USPSTF) updated lung cancer screening (LCS) recommendations with annual low-dose CT (LDCT) in 2021. We aimed to assess prevalence of patient-provider discussion about LCS and determine its associated factors. MATERIALS AND METHODS: Using data from Health Information National Trends Survey (HINTS) 2022 cycle 6, 2 cohorts were evaluated: (1) potentially LCS-eligible, included participants at least 50 years old with a history of smoking and no prior history of lung cancer; (2) LCS-ineligible individuals based on age (eg, 18-49 years old), smoking history (eg, never smoked), or history of lung cancer...
March 2, 2024: Clinical Lung Cancer
https://read.qxmd.com/read/38522901/efficacy-of-computed-tomography-based-evaluation-of-myocardial-extracellular-volume-combined-with-red-flags-for-early-screening-of-concealed-cardiac-amyloidosis-in-patients-with-atrial-fibrillation
#27
JOURNAL ARTICLE
Hirochika Yamasaki, Hidekazu Kondo, Tomoaki Shiroo, Naohiro Iwata, Teruaki Masuda, Taiki Makita, Yuki Iwabuchi, Kota Tanazawa, Masaki Takahashi, Yuma Ono, Naoko Ogawa, Taisuke Harada, Kazuki Mitarai, Shuichiro Yamauchi, Masayuki Takano, Nozomi Kodama, Kei Hirota, Miho Miyoshi, Keisuke Yonezu, Katsunori Tawara, Ichitaro Abe, Shotaro Saito, Akira Fukui, Tomoko Fukuda, Hidefumi Akioka, Tetsuji Shinohara, Kumiko Akiyoshi, Yasushi Teshima, Kunio Yufu, Tsutomu Daa, Etsuro Matsubara, Yoshiki Asayama, Mitsuharu Ueda, Naohiko Takahashi
BACKGROUND: The prevalence of transthyretin amyloid cardiomyopathy (ATTR-CM) in atrial fibrillation (AF) patients remains unclear. We explored the efficacy of computed tomography-based myocardial extracellular volume (CT-ECV) combined with red flags for the early screening of concealed ATTR-CM in AF patients undergoing catheter ablation.Methods and Results: Patients referred for AF ablation at Oita University Hospital were prescreened using the red-flag signs defined by echocardiographic or electrocardiographic findings, medical history, symptoms, and blood biochemical findings...
March 22, 2024: Circulation Journal: Official Journal of the Japanese Circulation Society
https://read.qxmd.com/read/38522564/morusin-inhibits-breast-cancer-induced-osteolysis-by-decreasing-phosphatidylinositol-3-kinase-pi3k-mtor-signalling
#28
JOURNAL ARTICLE
Long Zhang, Weibin Li, Xiaohui Chen, Dongmin Cao, Siyuan You, Fan Shi, Zhengqiong Luo, Hongyu Li, Xiangchen Zeng, Yabin Song, Na Li, Yoshie Akimoto, Gang Rui, Yu Chen, Zuoxing Wu, Ren Xu
Bone metastases caused by breast cancer pose a major challenge to the successful treatment of breast cancer patients. Many researchers have suggested that herbal medicines are extremely effective at preventing and treating cancer-associated osteolysis. Previous studies have revealed that Morusin (MOR) is cytotoxic to many cancer cells ex vivo. Nevertheless, how MOR contributes to osteolysis induced by breast cancer is still unknown, and the potential mechanism of action against osteolysis is worthy of further study...
March 22, 2024: Chemico-biological Interactions
https://read.qxmd.com/read/38521719/radiation-exposure-associated-with-computed-tomography-for-pediatric-urolithiasis-evaluation-a-scoping-review-of-the-literature
#29
REVIEW
Wyatt MacNevin, Michael Chua, Mareen Sarah Kraus, Daniel T Keefe
INTRODUCTION: Computed tomography (CT) imaging is used for assessment of pediatric urolithiasis in cases where ultrasound is inconclusive. The utility of CT imaging must be considered alongside the potential risks of radiation exposure in this patient population due to the increased risk of cancer development. The purpose of this review is to investigate the radiation exposure associated with standard-dose and low-dose computed tomography (CT) imaging for the assessment of pediatric urolithiasis...
March 14, 2024: Journal of Pediatric Urology
https://read.qxmd.com/read/38521635/the-paediatric-polytrauma-ct-indication-pepci-score-development-of-a-prognostic-model-to-reduce-unnecessary-ct-scans-in-paediatric-trauma-patients
#30
JOURNAL ARTICLE
Strahl André, Willemsen Jan Fritjof, Schoof Benjamin, Reinshagen Konrad, Frosch Karl-Heinz, Wintges Kristofer
BACKGROUND: Whole-Body CT (WBCT) is frequently used in emergency situations for promptly diagnosing paediatric polytrauma patients, given the challenges associated with obtaining precise details about the mechanism and progression of trauma. However, WBCT does not lead to reduced mortality in paediatric patients, but is associated with high radiation exposure. We therefore wanted to develop a screening tool for CT demand-driven emergency room (ER)-trauma diagnostic to reduce radiation exposure in paediatric patients...
March 11, 2024: Injury
https://read.qxmd.com/read/38521484/considerable-variation-in-current-coronoid-height-and-fracture-measurement-techniques-a-systematic-review
#31
REVIEW
Mithun A Joshi, Niall Jj Bains, Andrew Jm Stone, Lucy J Wells, Joideep S Phadnis
BACKGROUND: Coronoid fractures usually occur in the presence of a significant osseo-ligamentous injury to the elbow. Fracture size and location correlate with degree of instability and many authors have attempted to analyze the effect of fracture variation on decision making and outcome. There remains no standardized technique for measuring coronoid height or fracture size. The aim of this study was to appraise the literature regarding techniques for coronoid height measurement in order to understand variation...
March 21, 2024: Journal of Shoulder and Elbow Surgery
https://read.qxmd.com/read/38518807/interaction-between-xrcc2-gene-polymorphism-and-abdominal-obesity-on-risk-of-endometrial-carcinoma
#32
JOURNAL ARTICLE
Wenjuan Tian, Siyu Cao, Wei Zhang, Chenlian Quan, Meiqin Zhang, Yan Huang
AIMS: The aim of this study was to investigate the impact of three single nucleotide polymorphisms (SNPs) within X-Ray Repair Cross Complementary Group 2 (XRCC2) gene and additional gene- abdominal obesity (AO) interaction with endometrial carcinoma (EC) risk. METHODS: Hardy-Weinberg equilibrium was tested for all participants by using SNPstats (online software: https://bioinfo.iconcologia.net/SNPstats). The best SNP-SNP and gene-AO interaction combination among three SNPs within XRCC2 gene and AO was screened using generalized multifactor dimensionality reduction (GMDR)...
February 12, 2024: Gynecological Endocrinology
https://read.qxmd.com/read/38518565/fracture-variation-in-survivable-versus-fatal-blunt-force-trauma-associated-with-intimate-partner-violence
#33
JOURNAL ARTICLE
Nicole M Saenz, Sean D Tallman
Intimate partner violence (IPV) is a global human rights issue that affects approximately 25% of women and 10% of men and is the leading cause of homicides of women worldwide. Multiple interventional studies have been conducted to screen for IPV; however, fractures associated with intimate partner homicide (IPH) have not been studied from a forensic anthropological perspective. Therefore, this study uses computed tomography scans of IPH victims (n=33) obtained from the New Mexico Office of the Medical Investigator to 1) classify and quantify perimortem craniofacial blunt force fractures, and 2) compare the IPH-related fractures to those associated with non-lethal IPV using previously published studies...
March 18, 2024: Forensic Science International
https://read.qxmd.com/read/38517664/diagnostic-prediction-of-gastrointestinal-graft-versus-host-disease-based-on-a-clinical-ct-signs-nomogram-model
#34
JOURNAL ARTICLE
Qing Feng, Fengming Xu, Kaiming Guan, Tao Li, Jing Sheng, Wei Zhong, Haohua Wu, Bing Li, Peng Peng
OBJECTIVE: Gastrointestinal graft-versus-host disease (GI-GVHD) is one of the complications that can easily occur after hematopoietic stem cell transplantation (HSCT). Timely diagnosis and treatment are pivotal factors that greatly influence the prognosis of patients. However, the current diagnostic method lacks adequate non-invasive diagnostic tools. METHODS: A total of 190 patients who suspected GI-GVHD were retrospectively included and divided into training set (n = 114) and testing set (n = 76) according to their discharge time...
March 22, 2024: Insights Into Imaging
https://read.qxmd.com/read/38517085/triage-tools-for-detecting-cervical-spine-injury-in-paediatric-trauma-patients
#35
REVIEW
Emma Tavender, Nitaa Eapen, Junfeng Wang, Vanessa C Rausa, Franz E Babl, Natalie Phillips
BACKGROUND: Paediatric cervical spine injury (CSI) after blunt trauma is rare but can have severe consequences. Clinical decision rules (CDRs) have been developed to guide clinical decision-making, minimise unnecessary tests and associated risks, whilst detecting all significant CSIs. Several validated CDRs are used to guide imaging decision-making in adults following blunt trauma and clinical criteria have been proposed as possible paediatric-specific CDRs. Little information is known about their accuracy...
March 22, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38516493/unveiled-a-case-of-n-methyl-d-aspartate-receptor-antibody-encephalitis-with-delayed-diagnosis-of-ovarian-teratoma
#36
Patricia Fleur J Andaya, Alejandro Bimbo F Diaz
N-methyl-D-aspartate receptor (NMDAR) antibody encephalitis is an autoimmune syndrome with potentially fatal sequelae causing profound dysregulation of neurotransmission. Patients most often present with a constellation of neuropsychiatric signs and symptoms, including behavioral changes, motor disturbances, and seizures. Frequently, the development of anti-NMDAR antibodies has been linked to specific malignancies, although the exact event that triggers the production of these antibodies remains unknown...
February 2024: Curēus
https://read.qxmd.com/read/38516169/keratoconus-exploring-fundamentals-and-future-perspectives-a-comprehensive-systematic-review
#37
REVIEW
Sana Niazi, Zisis Gatzioufas, Farideh Doroodgar, Oliver Findl, Alireza Baradaran-Rafii, Jacob Liechty, Majid Moshirfar
BACKGROUND: New developments in artificial intelligence, particularly with promising results in early detection and management of keratoconus, have favorably altered the natural history of the disease over the last few decades. Features of artificial intelligence in different machine such as anterior segment optical coherence tomography, and femtosecond laser technique have improved safety, precision, effectiveness, and predictability of treatment modalities of keratoconus (from contact lenses to keratoplasty techniques)...
2024: Therapeutic Advances in Ophthalmology
https://read.qxmd.com/read/38515138/cardiovascular-disease-in-alpha-1-antitrypsin-deficiency-an-observational-study-assessing-the-role-of-neutrophil-proteinase-activity-and-the-suitability-of-validated-screening-tools
#38
JOURNAL ARTICLE
E Sapey, L E Crowley, R G Edgar, D Griffiths, S Samanta, H Crisford, C E Bolton, J R Hurst, R A Stockley
BACKGROUND: Alpha 1 Antitrypsin Deficiency (AATD) is a rare, inherited lung disease which shares features with Chronic Obstructive Pulmonary Disease (COPD) but has a greater burden of proteinase related tissue damage. These proteinases are associated with cardiovascular disease (CVD) in the general population. It is unclear whether patients with AATD have a greater risk of CVD compared to usual COPD, how best to screen for this, and whether neutrophil proteinases are implicated in AATD-associated CVD...
March 21, 2024: Orphanet Journal of Rare Diseases
https://read.qxmd.com/read/38514506/-screening-risk-stratification-and-ct-imaging-for-assessment-of-coronary-artery-disease
#39
REVIEW
Leon M Bischoff, Julian A Luetkens
BACKGROUND: Early treatment of cardiovascular risk factors and characterization of coronary plaques is essential to collect prognostic information about coronary artery disease (CAD) and prevent cardiovascular events. OBJECTIVES: Discussion of the most important risk factors of CAD, basic diagnostic of CAD, prevention, and prognostic factors of CAD with focus on cardiac computed tomography (CT). MATERIALS AND METHODS: Prevalence and prognostic impact of CAD risk factors; description of specific assessment of risk profiles; estimation of pretest probability; conventional prevention of CAD; prognostic assessment of CAD using the Calcium Scoring and coronary CT angiography...
March 21, 2024: Radiologie (Heidelb)
https://read.qxmd.com/read/38514364/hydrochloric-acid-induced-acute-lung-injury-models-dynamic-change-and-quantitative-analysis-of-modified-lung-ultrasound-scoring-system-and-high-resolution-computed-tomography
#40
JOURNAL ARTICLE
Jingyi Guo, Youkuan Ou, Qiuyue Liu, Kunzhang Zeng, Yijun Huang, Fuqiang Yan, Mingli Cai, Guorong Lyu
OBJECTIVE: Acute lung injury (ALI) has become a research hotspot due to its significant public health impact. To explore the value of the use of modified lung ultrasound (MLUS) scoring system for evaluating ALI using a rabbit model of ALI induced by hydrochloric acid (HCl) and investigate its correlation with high-resolution computed tomography (HRCT) and histopathological scores. METHODS: Twenty New Zealand laboratory rabbits were randomly assigned to control group (N = 5) and 3 experimental groups (N = 5 each)...
March 20, 2024: Ultrasound in Medicine & Biology
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