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https://www.readbyqxmd.com/read/29783225/-features-of-exchange-of-calcium-saliva-in-patients-with-gastroesophageal-reflux-disease
#1
Mykola А Bychkov, Maryana М Yakhnitska
OBJECTIVE: Introduction: The pathogenesis of gastroesophageal reflux disease (GERD) is a topical issue of modern gastroenterology. There are a number of scientific papers on changes in the qualitative and quantitative composition of saliva, which triggers a cascade of biochemical reactions, the consequence of which is the destruction of the resistance of the mucous membrane of the esophagus. Calcium is a macro element that provides the normal functioning of cells. Parathormone also regulates the metabolism of calcium in the body...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783206/-experimental-evaluation-of-the-therapeutic-potential-of-liposome-mediated-apoe3-gene-transfection-for-cerebral-atherosclerosis
#2
Vadym V Biloshytskyi, Alisa V Pachevska, Alina V Biloshytska, Valerii M Istoshyn, Maryna V Biloshytska, Olha B Shevnia
OBJECTIVE: Introduction: In recent years, a stroke has been the cause of high lethality, long-term and sustained disability, the problem of which is still far from being resolved. The root cause of stroke is atherosclerosis. The aim: Study of neurotrophic and neuroprotective functions of apoE in rat brain tissue in experimental atherosclerosis. PATIENTS AND METHODS: Materials and methods: The study included 60 sexually mature rats. The model of experimental atherosclerosis was created by Anichkov method...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783203/mechanical-characterization-and-ion-release-of-bioactive-dental-composites-containing-calcium-phosphate-particles
#3
Livia C Natale, Marcela C Rodrigues, Yvette Alania, Marina D S Chiari, Leticia C C Boaro, Marycel Cotrim, Oscar Vega, Roberto R Braga
OBJECTIVE: to verify the effect of the addition of dicalcium phosphate dihydrate (DCPD) particles functionalized with di- or triethylene glycol dimethacrylate (DEGDMA or TEGDMA) on the degree of conversion (DC), post-gel shrinkage (PS), mechanical properties, and ion release of experimental composites. METHODS: Four composites were prepared containing a BisGMA/TEGDMA matrix and 60 vol% of fillers. The positive control contained only barium glass fillers, while in the other composites 15 vol% of the barium was replaced by DCPD...
May 18, 2018: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/29783199/inhalational-exposure-to-particulate-matter-air-pollution-alters-the-composition-of-the-gut-microbiome
#4
Ece A Mutlu, Işın Y Comba, Takugo Cho, Phillip A Engen, Cemal Yazıcı, Saul Soberanes, Robert B Hamanaka, Recep Niğdelioğlu, Angelo Y Meliton, Andrew J Ghio, G R Scott Budinger, Gökhan M Mutlu
Recent studies suggest an association between particulate matter (PM) air pollution and gastrointestinal (GI) disease. In addition to direct deposition, PM can be indirectly deposited in oropharynx via mucociliary clearance and upon swallowing of saliva and mucus. Within the GI tract, PM may alter the GI epithelium and gut microbiome. Our goal was to determine the effect of PM on gut microbiota in a murine model of PM exposure via inhalation. C57BL/6 mice were exposed via inhalation to either concentrated ambient particles or filtered air for 8-h per day, 5-days a week, for a total of 3-weeks...
May 18, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29783190/importance-of-surface-modification-of-%C3%AE-alumina-in-creating-its-nanostructured-composites-with-zeolitic-imidazolate-framework-zif-67
#5
Yuanyuan Liu, Alexandre A S Gonçalves, Yang Zhou, Mietek Jaroniec
Application of zeolitic imidazolate framework-67 (ZIF-67) as an adsorbent has been greatly hindered by slow mass transfer of adsorbate molecules due to its inherent microporosity. To address this limitation, we have developed binary nanostructures composed of ZIF-67 and γ-alumina (GA) containing respectively micropores and large mesopores. The nanostructured composites were successfully prepared by coupling ZIF-67 and GA with and without surface modification with imidazole silane that mimics the building blocks of ZIF-67 to obtain GA-Im-ZIF-67 (with imidazole silane) and GA-ZIF-67 (without imidazole silane)...
May 7, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29783171/ghep-isfg-collaborative-exercise-on-mixture-profiles-ghep-mix06-reporting-conclusions-results-and-evaluation
#6
P A Barrio, M Crespillo, J A Luque, M Aler, C Baeza-Richer, L Baldassarri, E Carnevali, P Coufalova, I Flores, O García, M A García, R González, A Hernández, V Inglés, G M Luque, A Mosquera-Miguel, S Pedrosa, M L Pontes, M J Porto, Y Posada, M I Ramella, T Ribeiro, E Riego, A Sala, V G Saragoni, A Serrano, S Vannelli
One of the main goals of the Spanish and Portuguese-Speaking Group of the International Society for Forensic Genetics (GHEP-ISFG) is to promote and contribute to the development and dissemination of scientific knowledge in the field of forensic genetics. Due to this fact, GHEP-ISFG holds different working commissions that are set up to develop activities in scientific aspects of general interest. One of them, the Mixture Commission of GHEP-ISFG, has organized annually, since 2009, a collaborative exercise on analysis and interpretation of autosomal short tandem repeat (STR) mixture profiles...
May 18, 2018: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/29783170/impact-of-long-term-salinity-exposure-in-anaerobic-membrane-bioreactors-treating-phenolic-wastewater-performance-robustness-and-endured-microbial-community
#7
Julian D Muñoz Sierra, Margreet J Oosterkamp, Wei Wang, Henri Spanjers, Jules B van Lier
Industrial wastewaters are becoming increasingly associated with extreme conditions such as the presence of refractory compounds and high salinity that adversely affect biomass retention or reduce biological activity. Hence, this study evaluated the impact of long-term salinity increase to 20 gNa+ .L-1 on the bioconversion performance and microbial community composition in anaerobic membrane bioreactors treating phenolic wastewater. Phenol removal efficiency of up to 99.9% was achieved at 14 gNa+ .L-1 . Phenol conversion rates of 5...
May 7, 2018: Water Research
https://www.readbyqxmd.com/read/29783150/electrophoretic-deposition-of-dexamethasone-loaded-gelatin-nanospheres-chitosan-coating-and-its-dual-function-in-anti-inflammation-and-osteogenesis
#8
Hongfei Qi, Qiang Chen, Hailong Ren, Xianglong Wu, Xianhu Liu, Tingli Lu
Surface modification of metallic implants with bioactive and biodegradable coatings could be a promising approach for bone regeneration. The objective of this study was to prepare chitosan/gelatin nanospheres (GNs) composite coating for the delivery of dexamethasone (DEX). GNs with narrow size distribution and negative surface charge were firstly prepared by a two-step desolvation method. Homogeneous and stable gelatin nanospheres/chitosan (GNs/CTS) composite coatings were formed by electrophoretic deposition (EPD)...
May 18, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29783143/metallic-nanocatalysts-for-electrochemical-co-2-reduction-in-aqueous-solutions
#9
Yuanxing Wang, Cailing Niu, Dunwei Wang
How to effectively and efficiently reduce carbon dioxide (CO2 ) to value-added chemicals represent a frontier in catalysis research. Due to the high activation energy needs and the endothermic nature of CO2 reduction, the reactions are difficult to carry out. When H2 O is present, hydrogen evolution reactions (HER) often compete favorably with CO2 reduction reactions. For these reactions, catalysts are of critical importance to CO2 reduction. In this article, we review the various metal nanocatalysts for electrochemical CO2 reduction (ECR) reactions...
May 16, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29783141/graphene-oxide-and-carbon-nanodots-co-modified-biobr-nanocomposites-with-enhanced-photocatalytic-4-chlorophenol-degradation-and-mechanism-insight
#10
Songying Qu, Yuhan Xiong, Jun Zhang
Non-metallic graphene oxide (GO) and carbon nanodots (CDots) co-doped BiOBr ternary system (GO/CDots/BiOBr) were successfully synthesized via a simple one-step solvothermal process. The compositional characterization, optical and electrical properties of photocatalysts were investigated in detail. The prepared ternary photocatalysts possessed the excellent visible-light driven photocatalytic 4-chlorophenol (4-CP) degradation. Additionally, the 4-CP removal efficiencies decreased in the order of GO/CDots/BiOBr (88...
May 15, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29783137/body-composition-as-a-predictor-of-physical-performance-in-older-age-a-ten-year-follow-up-of-the-helsinki-birth-cohort-study
#11
Tuija M Mikkola, Mikaela B von Bonsdorff, Minna K Salonen, Mika Simonen, Pertti Pohjolainen, Clive Osmond, Mia-Maria Perälä, Taina Rantanen, Eero Kajantie, Johan G Eriksson
BACKGROUND: This study assessed how different measures of body composition predict physical performance ten years later among older adults. METHODS: The participants were 1076 men and women aged 57 to 70 years. Body mass index (BMI), waist circumference, and body composition (bioelectrical impedance analysis) were measured at baseline and physical performance (Senior Fitness Test) ten years later. Linear regression analyses were adjusted for age, education, smoking, duration of the follow-up and physical activity...
May 14, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29783121/the-influence-of-nail-blocking-conditions-in-cattle-femoral-fractures
#12
Leopoldo A Paolucci, Estevam B Las Casas, Rafael R Faleiros, Cahuê F R Paz, Sergio S Rocha Junior
BACKGROUND: To investigate the effect of different fixation strategies of the intramedullary interlocking nail (IIN) on the mechanical behavior of a polymeric implant applied for femoral fracture fixation in calves, and to evaluate the performance of a glass fiber-reinforced polymer applied in a bovine femoral fracture reduction system, five Holstein male animals with a mean weight (±SD) of 62.8 ± 20.4 kg and aged 74 ± 15 were used to generate biomechanical parameters for this study...
May 7, 2018: Research in Veterinary Science
https://www.readbyqxmd.com/read/29783114/geosphere-biosphere-circulation-of-chemical-elements-in-soil-and-plant-systems-from-a-100-km-transect-from-southern-central-norway
#13
Clemens Reimann, Karl Fabian, Belinda Flem, Malin Andersson, Peter Filzmoser, Peter Englmaier
Geochemical element separation is studied in 14 different sample media collected at 41 sites along an approximately 100-km long transect north of Oslo. At each site, soil C and O horizons and 12 plant materials (birch/spruce/cowberry/blueberry leaves/needles and twigs, horsetail, braken fern, pine bark and terrestrial moss) were sampled. The observed concentrations of 29 elements (K, Ca, P, Mg, Mn, S, Fe, Zn, Na, B, Cu, Mo, Co, Al, Ba, Rb, Sr, Ti, Ni, Pb, Cs, Cd, Ce, Sn, La, Tl, Y, Hg, Ag) were used to investigate soil-plant relations, and to evaluate the element differentiation between different plants, or between foliage and twigs of the same plant...
May 17, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29783105/sterol-gradients-in-cells
#14
REVIEW
Anant K Menon
Cell organelles and the plasma membrane have unique lipid compositions. Consequently, there is a gradient of lipid-dependent properties along the secretory pathway. We focus here on the steep sterol gradients that exist between the endoplasmic reticulum and plasma membrane, as well as across the plasma membrane where sterols are found principally in the cytoplasmic leaflet. Recent progress in these areas has been remarkable, with new concepts and molecules to account for non-vesicular intracellular sterol transport, and an exciting new mechanism to explain the unexpected transbilayer distribution of sterols...
May 18, 2018: Current Opinion in Cell Biology
https://www.readbyqxmd.com/read/29783068/reliability-of-the-star-excursion-balance-test-and-two-new-similar-protocols-to-measure-trunk-postural-control
#15
Diego López-Plaza, Casto Juan-Recio, David Barbado, Iñaki Ruiz-Pérez, Francisco J Vera-Garcia
BACKGROUND: Although the Star Excursion Balance test (SEBT) has shown a good intra-session reliability the inter-session reliability of this test has not been deeply studied. Furthermore, there is an evident high influence of the lower-limbs in the performance of the SEBT so even if it has been used to measure core stability it is possibly not the most suitable measurement. OBJECTIVE: The aims of this study were: i) to assess the absolute and relative between-session reliability of the SEBT and two novel variations of this test to assess trunk postural control while sitting, i...
May 18, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29783055/characterization-and-coagulation-flocculation-performance-of-a-composite-flocculant-in-high-turbidity-drinking-water-treatment
#16
Xiang Xia, Shuhuan Lan, Xudong Li, Yifei Xie, Yajie Liang, Peihan Yan, Zhengyang Chen, Yunxiao Xing
Klebsiella variicola B16, a microbial bioflocculant (MBF-B16)-producing bacteria, was isolated and identified by its 16S rRNA sequence, biochemical properties, and physiological characteristics. The effects of culture conditions on MBF-B16 production, including carbon source, nitrogen source, C/N ratio, initial pH, and culture temperature, were investigated in this study. Results showed that 6.96 g of MBF-B16 could be extracted from a 1-L culture broth under optimized conditions. Chemical analysis showed that polysaccharide and protein were the main components...
April 30, 2018: Chemosphere
https://www.readbyqxmd.com/read/29782982/process-optimization-purification-and-characterization-of-a-novel-acidic-thermostable-chitinase-from-humicola-grisea
#17
Manish Kumar, Amandeep Brar, V Vivekanand, Nidhi Pareek
An extracellular acidic and thermostable chitinase (HgChi) from thermophilic Humicola grisea was purified and characterized. Enhancement in chitinase production (Qp  = 2.9662 Ul-1  h-1 ) was achieved through derivation of optimum fermentation conditions via central composite design. H. grisea observed to produce various isoforms of chitinase, among which the major expressed form has molecular mass of about 50 kDa. Purified chitinases exhibited optimal activity at pH 3.0 and 70 °C. Chitinase showed notable stability at increasing temperatures...
May 18, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29782977/preparation-and-properties-of-polylactic-acid-tea-polyphenol-chitosan-composite-membranes
#18
Jingsong Ye, Shuyao Wang, Weijie Lan, Wen Qin, Yaowen Liu
To study the properties of composite membranes consisting of polylactic acid (PLA), tea polyphenol (TP), and chitosan (CS), the stretch film method was employed to make PLA-TP- CS composite membranes of different concentrations. By testing the density, mechanical properties, heat-sealing performance, water vapor permeability, and solubility of the pure PLA membrane and the composite membranes, the comprehensive performance of the composite membranes were analyzed with regard to the actual use value. The results show that, compared with the pure PLA membrane, adding TP and CS significantly increases the heat-sealing strength, water vapor permeability, and solubility of the composite membrane...
May 18, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29782933/whole-genome-sequencing-and-analyses-identify-high-genetic-heterogeneity-and-diversity-of-rotavirus-genotype-p-6-strains-circulating-in-africa
#19
Martin M Nyaga, Yi Tan, Mapaseka L Seheri, Rebecca A Halpin, Asmik Akopov, Karla M Stucker, Nadia B Fedorova, Susmita Shrivastava, A Duncan Steele, Jason M Mwenda, Brett E Pickett, Suman R Das, M Jeffery Mphahlele
Rotavirus A (RVA) exhibits a wide genotype diversity globally. Little is known about the genetic composition of genotype P[6] from Africa. This study investigated possible evolutionary mechanisms leading to genetic diversity of genotype P[6] VP4 sequences. Phylogenetic analyses on 167 P[6] VP4 full-length sequences were conducted, which included six porcine-origin sequences. Of the 167 sequences, 57 were newly acquired through whole genome sequencing as part of this study. The other 110 sequences were all publicly-available global P[6] VP4 full-length sequences downloaded from GenBank...
May 18, 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29782919/animal-models-to-study-bile-acid-metabolism
#20
REVIEW
Jianing Li, Paul A Dawson
The use of animal models, particularly genetically modified mice, continues to play a critical role in studying the relationship between bile acid metabolism and human liver disease. Over the past 20 years, these studies have been instrumental in elucidating the major pathways responsible for bile acid biosynthesis and enterohepatic cycling, and the molecular mechanisms regulating those pathways. This work also revealed bile acid differences between species, particularly in the composition, physicochemical properties, and signaling potential of the bile acid pool...
May 18, 2018: Biochimica et Biophysica Acta
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