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https://www.readbyqxmd.com/read/28732345/multichannel-electroanalytical-devices-for-competitive-elisa-of-phenylethanolamine-a
#1
Yang Liu, Meng Cai, Weiping Wu, Yuting Fang, Pei She, Shouming Xu, Jianguo Li, Kang Zhao, Jingjuan Xu, Ning Bao, Anping Deng
Herein, we reported a disposable electroanalytical device for competitive enzyme-linked immunosorbent assay (ELISA) of phenylethanolamine A (PA). Conductive carbon tape coated with gold cluster served as the working electrode, while the counter and reference electrodes were fabricated on the filter paper by the screen-printing technique. Separating fabrication of the working electrode from other electrodes could make it possible for full utilization of the working electrode modification in bulk and no contamination of the immune-reagents on the counter and reference electrodes...
April 11, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28731929/impact-of-aortic-rather-than-brachial-pulsatile-haemodynamics-on-variations-in-end-organ-measures-across-the-full-adult-blood-pressure-range
#2
Bryan Hodson, Gavin R Norton, Imraan Ballim, Carlos D Libhaber, Pinhas Sareli, Angela J Woodiwiss
AIMS: To determine the extent to which the adverse effects of blood pressure (BP) are mediated by pulsatile haemodynamic changes across the normotensive as compared with the hypertensive adult brachial BP range, and whether aortic rather than brachial pulsatile changes best index these effects. METHODS: In 1307 community participants, the contribution of pulsatile haemodynamics (applanation tonometry and SphygmoCor software) to variations in left ventricular mass index (LVMI) (echocardiography) (n = 920), carotid intima-media thickness (IMT) (n = 712) and estimated glomerular filtration rate (eGFR) (n = 1164) were assessed...
July 20, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28731768/self-organized-velocity-pulses-of-dense-colloidal-suspensions-in-microchannel-flow
#3
Philipp Kanehl, Holger Stark
We present a numerical study of dense colloidal suspensions in a pressure-driven microchannel flow in two dimensions. The colloids are modeled as elastic and frictional spheres suspended in a Newtonian fluid, which we simulate using the method of multiparticle collision dynamics. The model reproduces periodic velocity and density pulse trains, traveling upstream in the microchannel, which are found in experiments conducted by Isa et al. [Phys. Rev. Lett. 102, 058302 (2009)PRLTAO0031-900710.1103/PhysRevLett...
July 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28731490/lancisi-s-sign-and-central-venous-catheter-tip-position-a-case-report
#4
Valentina Vigo, Piero Lisi, Giuseppe Galgano, Carlo Lomonte
INTRODUCTION: Valvular disease and pulmonary hypertension are common conditions in haemodialysis patients. In presence of tricuspid regurgitation, an increased retrograde blood flow into the right atrium during ventricle systole results in a typical modification of the normal venous waveform, creating a giant c-v wave. This condition clinically appears as a venous palpable pulsation within the internal jugular vein, also known as Lancisi's sign. CASE REPORT: An 83-year-old woman underwent haemodialysis for 9 years...
July 19, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28730800/optimizing-the-role-of-transthoracic-echocardiography-to-improve-the-cardiovascular-risk-stratification-the-dream-of-subclinical-coronary-artery-disease-detection
#5
Giovanni Benfari, Andrea Rossi, Giulia Geremia, Giulia Vinco, Carlo Zivelonghi, Aldo D Milano, Leonardo Gottin, Flavio L Ribichini, Francesco Onorati, Giuseppe Faggian
Detecting coronary artery disease at a subclinical level has always been a challenging task for cardiologists. Various non-invasive echocardiographic approaches such as measurements of left ventricular hypertrophy, diastolic function, left atrial enlargement, valve sclerosis and calcification, epicardial fat thickness, and pulse wave velocity have been proposed to integrate the available risk-charts. The present review is a collection of evidence that supports the role of the above mentioned features in cardiac risk stratification, summarizing the state of the art in non-invasive echocardiographic coronary risk assessment...
July 21, 2017: Minerva Medica
https://www.readbyqxmd.com/read/28729696/effects-of-cardiac-timing-and-peripheral-resistance-on-measurement-of-pulse-wave-velocity-for-assessment-of-arterial-stiffness
#6
Hanguang Xiao, Mark Butlin, Isabella Tan, Alberto Avolio
To investigate the effects of heart rate (HR), left ventricular ejection time (LVET) and wave reflection on arterial stiffness as assessed by pulse wave velocity (PWV), a pulse wave propagation simulation system (PWPSim) based on the transmission line model of the arterial tree was developed and was applied to investigate pulse wave propagation. HR, LVET, arterial elastic modulus and peripheral resistance were increased from 60 to 100 beats per minute (bpm), 0.1 to 0.45 seconds, 0.5 to 1.5 times and 0.5 to 1...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729675/oxygen-induced-impairment-in-arterial-function-is-corrected-by-slow-breathing-in-patients-with-type-1-diabetes
#7
Luciano Bernardi, Daniel Gordin, Marco Bordino, Milla Rosengård-Bärlund, Anna Sandelin, Carol Forsblom, Per-Henrik Groop
Hyperoxia and slow breathing acutely improve autonomic function in type-1 diabetes. However, their effects on arterial function may reveal different mechanisms, perhaps potentially useful. To test the effects of oxygen and slow breathing we measured arterial function (augmentation index, pulse wave velocity), baroreflex sensitivity (BRS) and oxygen saturation (SAT), during spontaneous and slow breathing (6 breaths/min), in normoxia and hyperoxia (5 L/min oxygen) in 91 type-1 diabetic and 40 age-matched control participants...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729510/tailored-semiconductors-for-high-harmonic-optoelectronics
#8
Murat Sivis, Marco Taucer, Giulio Vampa, Kyle Johnston, André Staudte, Andrei Yu Naumov, D M Villeneuve, Claus Ropers, P B Corkum
The advent of high-harmonic generation in gases 30 years ago set the foundation for attosecond science and facilitated ultrafast spectroscopy in atoms, molecules, and solids. We explore high-harmonic generation in the solid state by means of nanostructured and ion-implanted semiconductors. We use wavelength-selective microscopic imaging to map enhanced harmonic emission and show that the generation medium and the driving field can be locally tailored in solids by modifying the chemical composition and morphology...
July 21, 2017: Science
https://www.readbyqxmd.com/read/28728487/feasibility-and-characteristics-of-arterial-stiffness-measurement-in-preschool-children
#9
Maaike M Vanderschuren, Cuno Spm Uiterwaal, Cornelis K van der Ent, Jacobien B Eising
Background Arterial stiffness is an important predictor of cardiovascular risk in adult life. Increased arterial stiffness can also be present in children and may be associated with several other cardiovascular risk factors. Until now, however, we know little about measuring arterial stiffness in preschool children. In this study, we assessed the feasibility of measuring arterial stiffness in preschool children and explored possible determinants related to arterial stiffness at this age. Methods We studied 168 healthy children, aged 3...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28728486/relationship-between-neck-circumference-insulin-resistance-and-arterial-stiffness-in-overweight-and-obese-subjects
#10
Francesco Fantin, Gabriele Comellato, Andrea P Rossi, Elisa Grison, Elena Zoico, Gloria Mazzali, Mauro Zamboni
Background Only a few studies have investigated the relationship between neck circumference and cardiometabolic risk. The aim of this study was to assess the relationships between neck circumference, waist circumference, metabolic variables and arterial stiffness in a group of overweight and obese subjects evaluating a possible independent role of neck circumference in determining arterial stiffness. Methods and results We studied 95 subjects (53 women) with an age range of 20-77 years and body mass index range from 25...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28728481/feasibility-of-two-dimensional-speckle-tracking-in-evaluation-of-arterial-stiffness-comparison-with-pulse-wave-velocity-and-conventional-sonographic-markers-of-atherosclerosis
#11
Michał Podgórski, Piotr Grzelak, Magdalena Kaczmarska, Michał Polguj, Maciej Łukaszewski, Ludomir Stefańczyk
Objective Arterial stiffening is an early marker of atherosclerosis that has a prognostic value for cardiovascular morbidity and mortality. Although many markers of arterial hardening have been proposed, the search is on for newer, more user-friendly and reliable surrogates. One such potential candidate has emerged from cardiology, the speckle-tracking technique. The aim of this study was to evaluate the feasibility of the two-dimensional speckle tracking for the evaluation of arterial wall stiffness in comparison with standard stiffness parameters...
January 1, 2017: Vascular
https://www.readbyqxmd.com/read/28727156/safety-and-effectiveness-of-a-6-french-mri-conditional-pacemaker-lead-the-ingevitytm-clinical-investigation-study-results
#12
Jens C Nielsen, Michael Giudici, Jose Maria Tolasana Viu, Engwooi Chew, Elke Sommerijns, Nicholas Wold, Linda Evert, Charles J Love, Kenneth Stein, Hedrich Olaf
BACKGROUND: The design of pacemaker leads has continued to evolve; ease of lead handling, improved electrical performance and MRI conditional aspects have become more important, while safety remains critical. The INGEVITY™ family leads was designed to provide MRI conditional aspects, decreased diameter, and improved performance of pacemaker leads. The INGEVITY study is an investigational device exemption trial evaluating the acute and chronic safety and effectiveness of these leads...
July 20, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28726940/measurement-of-specific-heat-and-thermal-conductivity-of-supported-and-suspended-graphene-by-a-comprehensive-raman-optothermal-method
#13
Qin-Yi Li, Kailun Xia, Ji Zhang, Yingying Zhang, Qunyang Li, Koji Takahashi, Xing Zhang
The last decade has seen the rapid growth of research on two-dimensional (2D) materials, represented by graphene, but research on their thermophysical properties is still far from sufficient owing to the experimental challenges. Herein, we report the first measurement of the specific heat of multilayer and monolayer graphene in both supported and suspended geometries. Their thermal conductivities were also simultaneously measured using a comprehensive Raman optothermal method without needing to know the laser absorption...
July 20, 2017: Nanoscale
https://www.readbyqxmd.com/read/28726571/primary-blast-causes-delayed-effects-without-cell-death-in-shell-encased-brain-cell-aggregates
#14
Thomas Sawyer, Yushan Wang, David V Ritzel, Tyson Josey, Mercy Villanueva, Cory Vair, Yanfeng Song, Yimin Shei, Steven Parks, Peggy Nelson, Grant Hennes, Lori McLaws, Changyan Fan
Previous work used underwater explosive exposures to isolate the effects of shock-induced principle stress without shear on rat brain aggregate cultures. This current study has utilized simulated air blast to expose aggregates in suspension and enclosed within a spherical shell, enabling the examination of a much more complex biomechanical insult. Culture medium-filled spheres were exposed to single pulse overpressures of 15-30 psi (6-7 msec duration) and measurements within the sphere at defined sites showed complex and spatially dependent pressure changes...
July 20, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28725994/evaluation-of-the-effects-of-photobiomodulation-on-vertebras-in-two-rat-models-of-experimental-osteoporosis
#15
Mohammadjavad Fredoni, Mahdi Ghatrehsamani, Mohammad-Amin Abdollahifar, Sahar Bayat, Mohammad Bayat
The aim of this study was to evaluate the effects of photobiomodulation (PBM) on cancellous bone in rat models of ovariectomized induced osteoporosis (OVX-D) and glucocorticoid-induced osteoporosis (GIOP). The experiment comprised of nine groups. A group of healthy rats was used for baseline evaluations. The OVX-D rats were further divided into groups as follows: control rats with osteoporosis, OVX-D rats that received alendronate (1 mg/kg 60 days), OVX-D rats treated with pulsed wave laser (890 nm, 80 Hz, 900 s, 0...
July 19, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28724946/diastolic-augmentation-index-improves-radial-augmentation-index-in-assessing-arterial-stiffness
#16
Yang Yao, Liling Hao, Lisheng Xu, Yahui Zhang, Lin Qi, Yingxian Sun, Benqiang Yang, Frans N van de Vosse, Yudong Yao
Arterial stiffness is an important risk factor for cardiovascular events. Radial augmentation index (AI r ) can be more conveniently measured compared with carotid-femoral pulse wave velocity (cfPWV). However, the performance of AI r in assessing arterial stiffness is limited. This study proposes a novel index AI rd , a combination of AI r and diastolic augmentation index (AI d ) with a weight α, to achieve better performance over AI r in assessing arterial stiffness. 120 subjects (43 ± 21 years old) were enrolled...
July 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28724570/childhood-thyroid-function-body-composition-and-cardiovascular-function
#17
Mirjana Barjaktarovic, Tim Korevaar, Romy Gaillard, Yolanda B de Rijke, Theo J Visser, Vincent Wv Jaddoe, Robin P Peeters
OBJECTIVE: The cardiovascular system is a known target for thyroid hormone. Early-life cardiovascular alterations may lead to a higher risk of cardiovascular disease in adulthood. Little is known about the effects of thyroid hormone on cardiovascular function during childhood, including the role of body composition in this association. DESIGN: Population-based prospective cohort of children (N=4251, median age 6 years, 95% range 5.7-8.0 years). METHODS: Thyroid stimulating hormone (TSH) and free thyroxine (FT4) concentrations were measured to assess thyroid function...
July 19, 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/28723965/the-prevalence-and-metabolic-characteristics-of-polycystic-ovary-syndrome-in-the-qatari-population
#18
Soha R Dargham, Lina Ahmed, Eric S Kilpatrick, Stephen L Atkin
OBJECTIVE: The prevalence of polycystic ovary syndrome (PCOS) in the Qatari population is unknown and hence the estimated impact on the local population cannot be determined. The purpose of this study was to estimate the prevalence and metabolic features of PCOS among Qatari women. DESIGN: Cross sectional analysis. PATIENTS: 3,017 Qatari subjects volunteered to be phenotyped and genotyped for the Qatar Biobank from which all women between the ages of 18-40 years were identified (750)...
2017: PloS One
https://www.readbyqxmd.com/read/28723110/portable-sensor-for-the-detection-of-choline-and-its-derivatives-based-on-silica-isoporous-membrane-and-gellified-nanointerfaces
#19
Lisiqi Xie, Xiao Huang, Bin Su
A portable amperometric ion sensor was fabricated by integrating silica isoporous membrane (SIM) and organogel composed of polyvinyl chloride and 1,2-dichloroethane (PVC-DCE) on a 3D-printed polymer chip. The detection of ionic species in aqueous samples could be accomplished by adding a microliter of sample droplet to the sensor and by identifying the ion-transfer potential and current magnitude at the water/organogel interface array templated by SIM. Thanks to the ultrasmall channel size (2-3 nm in diameter), high channel density (4 × 10(8) μm(-2)), and ultrathin thickness (80 nm) of SIM, the ensemble of nanoscopic water/organogel (nano-W/Gel) interface array behaved like a microinterface with two back-to-back hemispherical mass diffusion zones...
June 23, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28722185/valsalva-maneuver-exacerbates-left-atrial-compression-in-patients-with-large-hiatal-hernia
#20
Christopher Naoum, Leonard Kritharides, Sonali R Gnanenthiran, David Martin, Gregory L Falk, John Yiannikas
INTRODUCTION: Hiatal hernia (HH) can cause left atrial (LA) compression and impair LA filling. We evaluated the cardiac effects of preload reduction and abdominal strain induced by Valsalva maneuver (VM) in large HH patients. METHODS: LA and left ventricular (LV) dimensions were measured using 2D transthoracic echocardiography at rest and during VM in HH patients (n=55, 70±10 years) and controls (n=22, 67±6 years). Biplane LV volumes (n=39) and mitral inflow pulse-wave Doppler parameters (n=27) were also evaluated...
July 18, 2017: Echocardiography
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