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https://www.readbyqxmd.com/read/29221643/respiratory-and-cardiovascular-responses-to-walking-down-a-traffic-polluted-road-compared-with-walking-in-a-traffic-free-area-in-participants-aged-60-years-and-older-with-chronic-lung-or-heart-disease-and-age-matched-healthy-controls-a-randomised-crossover
#1
Rudy Sinharay, Jicheng Gong, Benjamin Barratt, Pamela Ohman-Strickland, Sabine Ernst, Frank Kelly, Junfeng Jim Zhang, Peter Collins, Paul Cullinan, Kian Fan Chung
BACKGROUND: Long-term exposure to pollution can lead to an increase in the rate of decline of lung function, especially in older individuals and in those with chronic obstructive pulmonary disease (COPD), whereas shorter-term exposure at higher pollution levels has been implicated in causing excess deaths from ischaemic heart disease and exacerbations of COPD. We aimed to assess the effects on respiratory and cardiovascular responses of walking down a busy street with high levels of pollution compared with walking in a traffic-free area with lower pollution levels in older adults...
December 5, 2017: Lancet
https://www.readbyqxmd.com/read/29221483/the-role-of-sleepiness-on-arterial-stiffness-improvement-after-cpap-therapy-in-males-with-obstructive-sleep-apnea-a-prospective-cohort-study
#2
Maria Alexandra Mineiro, Pedro Marques da Silva, Marta Alves, Ana Luísa Papoila, Maria João Marques Gomes, João Cardoso
BACKGROUND: Obstructive sleep apnea (OSA) is associated with increased cardiovascular risk. This study aim to assess differences in changes in arterial stiffness of two groups of patients, defined as having daytime sleepiness or not, after continuous positive airway pressure (CPAP) treatment. METHODS: A selected cohort of consecutive male patients, under 65 years old, with moderate to severe OSA and without great number of comorbidities was studied. The diagnosis was confirmed by home respiratory poligraphy...
December 8, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29221098/pulse-dynamics-of-dual-wavelength-dissipative-soliton-resonances-and-domain-wall-solitons-in-a-tm-fiber-laser-with-fiber-based-lyot-filter
#3
Pan Wang, Kangjun Zhao, Xiaosheng Xiao, Changxi Yang
We report on the first demonstration of dual-wavelength square-wave pulses in a thulium-doped fiber laser. Under appropriate cavity parameters, dual-wavelength dissipative soliton resonances (DSRs) and domain wall solitons (DWSs) are successively obtained. Meanwhile, dark pulses generation is achieved at the dual-wavelength DWSs region due to the overlap of the two domain wall pulses. The fiber-based Lyot filter, conducted by inserting PMF between an in-line PBS and a PD-ISO, facilitates the generation of dual-wavelength operation...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29221063/200-gb-s-transmission-using-a-dual-polarization-o-band-silicon-photonic-intensity-modulator-for-stokes-vector-direct-detection-applications
#4
Eslam El-Fiky, Mohamed Osman, Mohammed Sowailem, Alireza Samani, David Patel, Rui Li, Md G Saber, Yun Wang, Nicolas Abadia, Yannick D'Mello, David V Plant
We present a dual-polarization O-band silicon photonic (SiP) transmitter for intra-datacenter optical interconnects. The transmitter is built using two identical O-band traveling wave Mach-Zehnder modulators with an average VπL and a bandwidth at 1.5 V bias voltage of 2.88 V.cm and 24.5 GHz, respectively. We experimentally demonstrate the transmitter in a Stokes vector direct-detection (SV-DD) system for dual-polarization intensity modulated signals with 2-level and 4-level pulse amplitude modulation (DP-PAM2 and DP-PAM4) formats...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29221037/large-area-highly-crystalline-wse2-atomic-layers-for-ultrafast-pulsed-lasers
#5
Jinde Yin, Jiarong Li, Hao Chen, Jintao Wang, Peiguang Yan, Mengli Liu, Wenjun Liu, Wei Lu, Zihan Xu, Wenfei Zhang, Jinzhang Wang, Zhipei Sun, Shuangchen Ruan
Large-area and highly crystalline transition metal dichalcogenides (TMDs) films possess superior saturable absorption compared to the TMDs nanosheet counterparts, which make them more suitable as excellent saturable absorbers (SA) for ultrafast laser technology. Thus far, the nonlinear optical properties of large-scale WSe2 and its applications in ultrafast photonics have not yet been fully investigated. In this work, the saturable absorption of chemical vapor deposition (CVD) grown WSe2 films with large-scale and high quality are studied and the use of WSe2 films as a broadband SA for passively mode-locked fiber lasers at both 1...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29221036/direct-inscription-of-bragg-gratings-into-coated-fluoride-fibers-for-widely-tunable-and-robust-mid-infrared-lasers
#6
Gayathri Bharathan, Robert I Woodward, Martin Ams, Darren D Hudson, Stuart D Jackson, Alex Fuerbach
We report the development of a widely tunable all-fiber mid-infrared laser system based on a mechanically robust fiber Bragg grating (FBG) which was inscribed through the polymer coating of a Ho3+-Pr3+ co-doped double clad ZBLAN fluoride fiber by focusing femtosecond laser pulses into the core of the fiber without the use of a phase mask. By applying mechanical tension and compression to the FBG while pumping the fiber with an 1150 nm laser diode, a continuous wave (CW) all-fiber laser with a tuning range of 37 nm, centered at 2870 nm, was demonstrated with up to 0...
November 27, 2017: Optics Express
https://www.readbyqxmd.com/read/29219022/effectiveness-of-radiofrequency-hyperthermia-for-treating-cartilage-in-guinea-pigs-with-primary-osteoarthritis
#7
Kenji Takahashi, Hiroshi Nakamura, Hitoshi Ozawa, Sanshiro Hashimoto, Norio Iijima, Shimpei Higo, Hiroshi Watanabe, Yusuke Mochizuki, Shinro Takai
Objective Autophagy was reported to be essential for maintaining chondrocyte function, and reduced autophagy leads to osteoarthritis (OA). Previous studies showed involvement of heat shock stress in the control of autophagy in cells. This study sought to investigate the effect of hyperthermia on the expression of autophagy-related proteins in articular cartilage and the progression of naturally occurring OA in Hartley guinea pigs. Design Radiofrequency pulses of 13.56 MHz were applied to the animals' knees for 20 minutes to induce hyperthermia...
January 2018: Cartilage
https://www.readbyqxmd.com/read/29218774/impact-of-antiinfective-periodontal-therapy-on-parameters-of-vascular-health
#8
Yvonne Jockel-Schneider, Markus Bechtold, Imme Haubitz, Stefan Störk, Stefan Fickl, Inga Harks, Martin Eigenthaler, Oliver Vollrath, Johannes Baulmann, Ulrich Schlagenhauf
AIM: This study assessed the impact of antiinfective periodontal therapy on the status of vascular health. MATERIALS AND METHODS: Periodontal and vascular health of 55 patients with severe untreated chronic periodontitis was evaluated before and 12 months after antiinfective periodontal therapy. Observed parameters were bleeding on probing (BoP), pocket probing depth (PPD), periodontal inflamed surface area index (PISA), pulse wave velocity (PWV), augmentation index (AIx), central pulse pressure (PPao), and peripheral systolic pressure (RRsys)...
December 8, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29218633/characterization-of-the-one-electron-oxidized-cu-ii-salen-complexes-with-a-side-chain-aromatic-ring-the-effect-of-the-indole-ring-on-the-cu-ii-phenoxyl-radical-species
#9
Hiromi Oshita, Takayoshi Yoshimura, Seiji Mori, Fumito Tani, Yuichi Shimazaki, Osamu Yamauchi
To gain insights into the role of the proximal indole ring in the redox-active metal center as seen in galactose oxidase, we prepared the Cu(II)-salen-type complexes having a pendent indol-3-ylmethyl (1), methyl (2) or benzyl (3) group substituted on the ethylenediamine moiety and investigated the structures and redox properties by various physicochemical methods and theoretical calculations. Neutral complexes 1, 2, and 3 showed no significant difference in the UV-Vis-NIR and EPR spectra. One-electron oxidation of 1, 2, and 3 by addition of 1 equiv...
December 7, 2017: Journal of Biological Inorganic Chemistry: JBIC
https://www.readbyqxmd.com/read/29218461/triphasic-mitral-inflow-pattern-associated-with-hemodynamic-deterioration-in-anemia-or-mitral-regurgitation-a-report-of-two-cases
#10
Ikuo Misumi, Masanobu Ishii
We present two cases with a mid-diastolic mitral inflow peak called an "L wave" due to underlying diseases. Case 1 was an 81-year-old woman with severe anemia (hemoglobin level of 3.9 g/dL). Pulsed Doppler echocardiography showed an L wave that disappeared after transfusion of red cell concentrates. Case 2 was a 72-year-old woman with severe mitral regurgitation due to ruptured chordae tendineae. Pulsed Doppler echocardiography showed an L wave that disappeared after mitral valve repair. The present report suggests that both severe anemia and mitral regurgitation might have contributed to L wave formation, which suggests hemodynamic deterioration...
December 7, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29218407/short-vs-long-pulses-for-testing-knee-extensor-neuromuscular-properties-does-it-matter
#11
Caroline Giroux, Boris Roduit, Javier Rodriguez-Falces, Jacques Duchateau, Nicola A Maffiuletti, Nicolas Place
PURPOSE: The present study aimed at comparing knee extensor neuromuscular properties determined with transcutaneous electrical stimulation using two pulse durations before and after a standardized fatigue protocol. METHODS: In the first sub-study, 19 healthy participants (ten women and nine men; 28 ± 5 years) took part to two separate testing sessions involving the characterization of voluntary activation (twitch interpolation technique), muscle contractility (evoked forces by single and paired stimuli), and neuromuscular propagation (M-wave amplitude from vastus lateralis and vastus medialis muscles) obtained at supramaximal intensity with a pulse duration of either 0...
December 7, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29218066/arterial-stiffness-and-hypertension-which-comes-first
#12
Monica Ecobici, Claudiu Stoicescu
Arterial hypertension is one of the traditional risk factors involved in the development of cardiovascular events, while arterial stiffness is an independent predictor of cardiovascular disease in patients with hypertension. It seems that the risk factors involved in the pathology of uncontrolled hypertension are similar to those that contribute to the development of arterial stiffness. After evidence showed that arterial stiffness is an independent prognostic factor for the occurrence of cardiovascular events in patients with arterial hypertension, the importance of assessing arterial stiffness was recognized in a document drafted by the European Society of Hypertension in 2007...
September 2017: Mædica
https://www.readbyqxmd.com/read/29217881/reduced-baroreflex-sensitivity-decreased-heart-rate-variability-with-increased-arterial-stiffness-in-predialysis
#13
C Lal, M Kaur, A K Jaryal, K K Deepak, D Bhowmik, S K Agarwal
High cardiovascular morbidity and mortality is observed in predialytic chronic kidney disease (CKD) patients. The underlying mechanism of cardiovascular dysfunction often remains unclear. The present study was designed to perform multiparametric assessment of baroreflex sensitivity (BRS), arterial stiffness indices, and cardiovascular variabilities (heart rate variability [HRV] and blood pressure variability [BPV]) together in predialytic CKD patients; compare it with normal healthy controls; and determine their relationships in predialytic nondiabetic CKD patients...
November 2017: Indian Journal of Nephrology
https://www.readbyqxmd.com/read/29217568/attosecond-resolved-photoionization-of-chiral-molecules
#14
S Beaulieu, A Comby, A Clergerie, J Caillat, D Descamps, N Dudovich, B Fabre, R Géneaux, F Légaré, S Petit, B Pons, G Porat, T Ruchon, R Taïeb, V Blanchet, Y Mairesse
Chiral light-matter interactions have been investigated for two centuries, leading to the discovery of many chiroptical processes used for discrimination of enantiomers. Whereas most chiroptical effects result from a response of bound electrons, photoionization can produce much stronger chiral signals that manifest as asymmetries in the angular distribution of the photoelectrons along the light-propagation axis. We implemented self-referenced attosecond photoelectron interferometry to measure the temporal profile of the forward and backward electron wave packets emitted upon photoionization of camphor by circularly polarized laser pulses...
December 8, 2017: Science
https://www.readbyqxmd.com/read/29217236/accuracy-precision-and-trending-of-4-pulse-wave-analysis-techniques-in-the-postoperative-period
#15
Martin Geisen, Michael T Ganter, Sonja Hartnack, Omer Dzemali, Christoph K Hofer, Andreas Zollinger
OBJECTIVE: The aim of this study was to analyze the accuracy, precision, and trending ability of the following 4 pulse wave analysis devices to measure continuous cardiac output: PiCCO2 ([PCCO]; Pulsion Medical System, Munich, Germany); LiDCORapid ([LCCO]; LiDCO Ltd, London, UK); FloTrac/Vigileo ([FCCO]; Edwards Lifesciences, Irvine, CA); and Nexfin ([NCCO]; BMEYE, Amsterdam, The Netherlands). DESIGN: Prospective, observational clinical study. SETTING: Intensive care unit of a single-center, teaching hospital...
September 7, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29216483/additional-prognostic-value-of-brachial-ankle-pulse-wave-velocity-to-coronary-computed-tomography-angiography-in-patients-with-suspected-coronary-artery-disease
#16
In-Chang Hwang, Kwang Nam Jin, Hack-Lyoung Kim, You-Nui Kim, Moon-Sun Im, Woo-Hyun Lim, Jae-Bin Seo, Sang-Hyun Kim, Joo-Hee Zo, Myung-A Kim
BACKGROUND AND AIMS: Increased arterial stiffness is associated with a higher risk of future cardiovascular events. We aimed to investigate whether information about arterial stiffness provides additional prognostic value to coronary computed tomography angiography (CCTA) findings. METHODS: A total of 523 consecutive patients (mean age, 58.0 ± 10.3 years; male, 60.6%) with suspected coronary artery disease (CAD), who underwent CCTA and brachial-ankle pulse wave velocity (baPWV) measurement within a month, were retrospectively analyzed...
December 1, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29216203/dose-responses-of-vitamin-d3-supplementation-on-arterial-stiffness-in-overweight-african-americans-with-vitamin-d-deficiency-a-placebo-controlled-randomized-trial
#17
Anas Raed, Jigar Bhagatwala, Haidong Zhu, Norman K Pollock, Samip J Parikh, Ying Huang, Robyn Havens, Ishita Kotak, De-Huang Guo, Yanbin Dong
BACKGROUND: Clinical trials are scant and equivocal on whether vitamin D can ameliorate arterial stiffness, particularly in populations at high risk for vitamin D deficiency and cardiovascular disease (CVD). This study determined the dose-response effects of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency. METHODS: Seventy overweight African Americans (aged 13-45 years) with serum 25-hydroxyvitamin D [25(OH)D] levels ≤ 20 ng/mL were randomized to monthly oral supplementation of 18,000 IU (~600 IU/day, n = 17), 60,000 IU (~2000 IU/day, n = 18), or 120,000 IU (~4000 IU/day, n = 18) of vitamin D3 or placebo (n = 17) for 16-weeks...
2017: PloS One
https://www.readbyqxmd.com/read/29216174/spatiotemporal-diffraction-free-pulsed-beams-in-free-space-of-the-airy-and-bessel-type
#18
Nikolaos K Efremidis
We investigate the dynamics of spatiotemporal optical waves with one transverse dimension obtained as the intersections of the dispersion cone with a plane. We show that, by appropriate spectral excitations, the three different types of conic sections (elliptic, parabolic, and hyperbolic) can lead to optical waves of the Bessel, Airy, and modified Bessel types, respectively. We find closed form solutions that accurately describe the wave dynamics and unveil their fundamental properties.
December 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/29216151/asynchronous-and-synchronous-dual-wavelength-pulse-generation-in-a-passively-mode-locked-fiber-laser-with-a-mode-locker
#19
Guoqing Hu, Yingling Pan, Xin Zhao, Siyao Yin, Meng Zhang, Zheng Zheng
The evolution from asynchronous to synchronous dual-wavelength pulse generation in a passively mode-locked fiber laser is experimentally investigated by tailoring the intracavity dispersion. Through tuning the intracavity-loss-dependent gain profile and the birefringence-induced filter effect, asynchronous dual-wavelength soliton pulses can be generated until the intracavity anomalous dispersion is reduced to ∼8  fs/nm. The transition from asynchronous to synchronous pulse generation is then observed at an elevated pump power in the presence of residual anomalous dispersion, and it is shown that pulses are temporally synchronized at the mode-locker in the cavity...
December 1, 2017: Optics Letters
https://www.readbyqxmd.com/read/29215398/a-genetic-risk-score-for-fasting-plasma-glucose-is-independently-associated-with-arterial-stiffness-a-mendelian-randomization-study
#20
Mikael Gottsäter, George Hindy, Marju Orho-Melander, Peter M Nilsson, Olle Melander
BACKGROUND: Arterial stiffness is known to be associated with a number of clinical conditions including hypertension, diabetes and dyslipidemia, and may predict cardiovascular events and mortality. However, causal links are hard to establish. Results from genome-wide association studies have identified only a few single nucleotide polymorphisms associated with arterial stiffness, the results have been inconsistent between studies and overlap with other clinical conditions is lacking. Our aim was to investigate a potential shared set of risk single nucleotide polymorphisms between relevant cardiometabolic traits and arterial stiffness...
December 5, 2017: Journal of Hypertension
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