Xiao Han, Weijia Gao, Zhe Zhou, Yongli Li, Duo Sun, Heyi Gong, Mengyuan Jiang, Yulu Gan, Xin Fang, Yuanzheng Qi, Junjie Jiao, Jinghui Zhao
Clinically, open wounds caused by accidental trauma and surgical lesion resection are easily infected by external bacteria, hindering wound healing. Antibacterial photodynamic therapy has become a promising treatment strategy for wound infection. In this study, a novel antibacterial nanocomposite material (QMC NPs) was synthesized by curcumin, quaternized chitosan and mesoporous polydopamine nanoparticles. The results showed that 150 μg/mL QMC NPs had good biocompatibility and exerted excellent antibacterial activity against Staphylococcus aureus and Escherichia coli after blue laser irradiation (450 nm, 1 W/cm2 )...
April 3, 2024: International Journal of Biological Macromolecules