Meilian Huang, Yuanxiong Ma, Jin Qian, Inna M Sokolova, Caoqi Zhang, Khor Waiho, James Kar Hei Fang, Xiaowan Ma, Youji Wang, Menghong Hu
Pollution with anthropogenic contaminants including antibiotics and nanoplastics leads to gradual deterioration of the marine environment, which threatens endangered species such as the horseshoe crab Tachypleus tridentatus. We assessed the potential toxic mechanisms of an antibiotic (norfloxacin, 0, 0.5, 5 μg/L) and polystyrene nanoparticles (104 particles/L) in T. tridentatus using biomarkers of tissue redox status, molting, and gut microbiota. Exposure to single and combined pollutants led to disturbance of redox balance during short-term (7 days) exposure indicated by elevated level of a lipid peroxidation product, malondialdehyde (MDA)...
February 15, 2024: Journal of Hazardous Materials