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https://www.readbyqxmd.com/read/29052357/critical-sized-full-thickness-skin-defect-regeneration-using-ovine-small-intestinal-submucosa-with-or-without-mesenchymal-stem-cells-in-rat-model
#1
Morteza Rashtbar, Jamshid Hadjati, Jafar Ai, Sadegh Shirian, Issa Jahanzad, Mahmoud Azami, Shiva Asadpuor, Esmaeil Sadroddiny
Decellularized extracellular matrices (ECM) based materials are routinely used for a variety of clinical applications. Hereof, in vivo application of decellularized ovine small intestinal submucosal (DOSIS) layer as, a scaffold is yet to be investigated. In this study, the effectiveness of the DOSIS scaffold, with or without rat bone marrow mesenchymal stem cells (BM-MSCs), in full-thickness wound healing of critical-sized defect was experimentally studied in a rat model. The experimental groups included; group I (control), group II (DOSIS), and group III (BM-MSCs-seeded DOSIS)...
October 20, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29052356/in-vitro-biocompatibility-bioactivity-and-photoluminescence-properties-of-eu-3-sr-2-dual-doped-nano-hydroxyapatite-for-biomedical-applications
#2
Lakshmanaperumal Sundarabharathi, Hemalatha Parangusan, Deepalekshmi Ponnamma, Mariam Al Ali Al-Maadeed, Mahendran Chinnaswamy
In the present investigation, we have successfully synthesized luminescent Eu(3+) -doped and Eu(3+) /Sr(2+) codoped hydroxyapatite (HA) nanoparticles through sol-gel assisted precipitation method with the aim of developing novel biomaterials containing osteoblast mineral (Sr(2+) ) and luminescence activator (Eu(3+) ). The structure, morphology, thermal stability, and luminescence properties of the resultant spherical nanoparticles (50-100 nm diameters) were studied. Moreover, the in-vitro bioactivity of Eu0...
October 20, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29052337/magnetic-stimulus-responsive-vancomycin-drug-delivery-system-based-on-chitosan-microbeads-embedded-with-magnetic-nanoparticles
#3
Ankita Mohapatra, Michael A Harris, David LeVine, Madhav Ghimire, Jessica A Jennings, Bashir I Morshed, Warren O Haggard, Joel D Bumgardner, Sanjay R Mishra, Tomoko Fujiwara
Local antibiotic delivery can overcome some of the shortcomings of systemic therapy, such as low local concentrations and delivery to avascular sites. A localized drug delivery system (DDS), ideally, could also use external stimuli to modulate the normal drug release profile from the DDS to provide efficacious drug administration and flexibility to healthcare providers. To achieve this objective, chitosan microbeads embedded with magnetic nanoparticles were loaded with the antibiotic vancomycin and stimulated by a high frequency alternating magnetic field...
October 20, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29050949/high-frequency-of-trypanosomatids-in-gallery-forest-bats-of-a-neotropical-savanna
#4
João Lucas M Lourenço, Thaís T C Minuzzi-Souza, Larissa R Silva, Amanda C Oliveira, Vagner J Mendonça, Nadjar Nitz, Ludmilla M S Aguiar, Rodrigo Gurgel-Gonçalves
Bats are well-known hosts of trypanosomatids, though information about their role as reservoirs of these protozoans in the Brazilian savanna is poorly known. We aimed to analyze the occurrence of trypanosomatid species in bats occurring in remnants of gallery forests of Brasília, Federal District of Brazil. We sampled bats using mist nets in six sites, and we collected blood, wing fragments and oral swab samples from all captured individuals. Trypanosomatids were identified in the captured bats through sequencing of the SSUrRNA region and kDNA qPCR...
October 16, 2017: Acta Tropica
https://www.readbyqxmd.com/read/29050554/natural-variation-and-genetics-of-photoperiodism-in-wyeomyia-smithii
#5
William E Bradshaw, Christina M Holzapfel
Seasonal change in the temperate and polar regions of Earth determines how the world looks around us and, in fact, how we live our day-to-day lives. For biological organisms, seasonal change typically involves complex physiological and metabolic reorganization, the majority of which is regulated by photoperiodism. Photoperiodism is the ability of animals and plants to use day length or night length, resulting in life-historical transformations, including seasonal development, migration, reproduction, and dormancy...
2017: Advances in Genetics
https://www.readbyqxmd.com/read/29049417/decrypting-the-polyporus-dictyopus-complex-recovery-of-atroporus-ryvarden-and-segregation-of-neodictyopus-gen-nov-polyporales-basidiomyocta
#6
Melissa Palacio, Gerardo Lucio Robledo, Mateus Arduvino Reck, Emanuel Grassi, Aristóteles Góes-Neto, Elisandro Ricardo Drechsler-Santos
Polyporus dictyopus, with a large number of heterotypic synonyms, has been traditionally considered a species complex, characterized by wide morphological variation and geographic distribution. Thus, neotropical specimens previously identified as P. dictyopus from Amazonia, Cerrado and Atlantic Forest biomes were studied based on detailed macro- and micromorphological examination and phylogenetic analyses, using distinct ribosomal and protein-coding genomic regions: the nuclear ribosomal internal transcribed spacer (nrITS), nuclear ribosomal large subunit (nrLSU), and RNA polymerase II second subunit (RPB2)...
2017: PloS One
https://www.readbyqxmd.com/read/29047152/false-gold-safely-navigating-open-access-publishing-to-avoid-predatory-publishers-and-journals
#7
Terence V McCann, Meg Polacsek
AIM: To review and discuss predatory open access publishing in the context of nursing and midwifery and develop a set of guidelines that serve as a framework to help clinicians, educators and researchers avoid predatory publishers. BACKGROUND: Open access publishing is increasingly common across all academic disciplines. However, this publishing model is vulnerable to exploitation by predatory publishers, posing a threat to nursing and midwifery scholarship and practice...
October 19, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29046541/a-multi-species-synthesis-of-physiological-mechanisms-in-drought-induced-tree-mortality
#8
Henry D Adams, Melanie J B Zeppel, William R L Anderegg, Henrik Hartmann, Simon M Landhäusser, David T Tissue, Travis E Huxman, Patrick J Hudson, Trenton E Franz, Craig D Allen, Leander D L Anderegg, Greg A Barron-Gafford, David J Beerling, David D Breshears, Timothy J Brodribb, Harald Bugmann, Richard C Cobb, Adam D Collins, L Turin Dickman, Honglang Duan, Brent E Ewers, Lucía Galiano, David A Galvez, Núria Garcia-Forner, Monica L Gaylord, Matthew J Germino, Arthur Gessler, Uwe G Hacke, Rodrigo Hakamada, Andy Hector, Michael W Jenkins, Jeffrey M Kane, Thomas E Kolb, Darin J Law, James D Lewis, Jean-Marc Limousin, David M Love, Alison K Macalady, Jordi Martínez-Vilalta, Maurizio Mencuccini, Patrick J Mitchell, Jordan D Muss, Michael J O'Brien, Anthony P O'Grady, Robert E Pangle, Elizabeth A Pinkard, Frida I Piper, Jennifer A Plaut, William T Pockman, Joe Quirk, Keith Reinhardt, Francesco Ripullone, Michael G Ryan, Anna Sala, Sanna Sevanto, John S Sperry, Rodrigo Vargas, Michel Vennetier, Danielle A Way, Chonggang Xu, Enrico A Yepez, Nate G McDowell
Widespread tree mortality associated with drought has been observed on all forested continents and global change is expected to exacerbate vegetation vulnerability. Forest mortality has implications for future biosphere-atmosphere interactions of carbon, water and energy balance, and is poorly represented in dynamic vegetation models. Reducing uncertainty requires improved mortality projections founded on robust physiological processes. However, the proposed mechanisms of drought-induced mortality, including hydraulic failure and carbon starvation, are unresolved...
September 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/29045616/potential-impact-of-global-climate-change-on-benthic-deep-sea-microbes
#9
Roberto Danovaro, Cinzia Corinaldesi, Antonio Dell Anno, Eugenio Rastelli
Benthic deep-sea environments are the largest ecosystem on Earth, covering approximately 65% of the Earth surface. Microbes inhabiting this huge biome at all water depths represent the most abundant biological components and a relevant portion of the biomass of the biosphere, and play a crucial role in global biogeochemical cycles. Increasing evidence suggests that global climate changes are affecting also deep-sea ecosystems, both directly (causing shifts in bottom-water temperature, oxygen concentration and pH), and indirectly (through changes in surface oceans' productivity and in the consequent export of organic matter to the seafloor)...
October 13, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/29044948/intracellular-pathway-and-subsequent-transformation-of-hydroxyapatite-nanoparticles-in-the-saos-2-osteoblast-cell-line
#10
André L Rossi, Mariana M Longuinho, Marcelo N Tanaka, Marcos Farina, Radovan Borojevic, Alexandre M Rossi
Internalization of hydroxyapatite nanoparticles in SAOS-2 osteoblasts for 2 and 24 h was investigated in vitro using 5 and 50 µg/mL nanoparticles in culture medium. No cytotoxic effects were observed in a PrestoBlue viability assay. Focused ion beam-scanning electron microscopy and transmission electron microscopy were used to study nanoparticle trafficking inside cells and to characterize the physicochemical properties of the remodeled nanoparticles. Nanoparticles were actively internalized by cells and maintained in intracellular membrane-bound compartments...
October 17, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29044940/low-intrapatient-variability-of-histomorphological-findings-in-periprosthetic-tissues-from-revised-metal-ceramic-on-polyethylene-joint-arthroplasties
#11
Jana Vaculova, Jiri Gallo, Pavel Hurnik, Oldrich Motyka, Stuart B Goodman, Jana Dvorackova
The type of tissue response to implant by-products can be determined by examination of periprosthetic tissues. However, little is known about the most suitable location for tissue sampling. The main goal of this study was to evaluate the extent of variability in tissue response in relation to location of tissue sampling, implant fixation, age and sex in total joint arthroplasties with metal-on-polyethylene or ceramic-on-polyethylene bearing pairs. We processed 236 histology slides from 21 patients and focused on the association between the location of tissue samples and histological features...
October 16, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29040752/expansion-of-the-dehydrin-gene-family-in-the-pinaceae-is-associated-with-considerable-structural-diversity-and-drought-responsive-expression
#12
Juliana Stival Sena, Isabelle Giguère, Philippe Rigault, Jean Bousquet, John Mackay
Temperatures are expected to increase over the next century in all terrestrial biomes and particularly in boreal forests, where drought-induced mortality has been predicted to rise. Genomics research is helping to develop hypotheses regarding the molecular basis of drought tolerance and recent work proposed that the osmo-protecting dehydrin proteins have undergone a clade-specific expansion in the Pinaceae, a major group of conifer trees. The objectives of this study were to identify all of the putative members of the gene family, trace their evolutionary origin, examine their structural diversity and test for drought-responsive expression...
October 13, 2017: Tree Physiology
https://www.readbyqxmd.com/read/29038863/a-warmer-and-drier-climate-in-the-northern-sagebrush-biome-does-not-promote-cheatgrass-invasion-or-change-its-response-to-fire
#13
Christian D Larson, Erik A Lehnhoff, Lisa J Rew
Dryland shrub communities have been degraded by a range of disturbances and now face additional stress from global climate change. The spring/summer growing season of the North American sagebrush biome is projected to become warmer and drier, which is expected to facilitate the expansion of the invasive annual grass Bromus tectorum (cheatgrass) and alter its response to fire in the northern extent of the biome. We tested these predictions with a factorial experiment with two levels of burning (spring burn and none) and three climate treatments (warming, warming + drying, and control) that was repeated over 3 years in a Montana sagebrush steppe...
October 16, 2017: Oecologia
https://www.readbyqxmd.com/read/29038749/extending-seqenv-a-taxa-centric-approach-to-environmental-annotations-of-16s-rdna-sequences
#14
Ali Z Ijaz, Thomas C Jeffries, Umer Z Ijaz, Kelly Hamonts, Brajesh K Singh
Understanding how the environment selects a given taxon and the diversity patterns that emerge as a result of environmental filtering can dramatically improve our ability to analyse any environment in depth as well as advancing our knowledge on how the response of different taxa can impact each other and ecosystem functions. Most of the work investigating microbial biogeography has been site-specific, and logical environmental factors, rather than geographical location, may be more influential on microbial diversity...
2017: PeerJ
https://www.readbyqxmd.com/read/29037251/cytochrome-c-oxidase-subunit-1-gene-as-a-dna-barcode-for-discriminating-trypanosoma-cruzi-dtus-and-closely-related-species
#15
Marina Silva Rodrigues, Karina Alessandra Morelli, Ana Maria Jansen
BACKGROUND: The DNA barcoding system using the cytochrome c oxidase subunit 1 mitochondrial gene (cox1 or COI) is highly efficient for discriminating vertebrate and invertebrate species. In the present study, we examined the suitability of cox1 as a marker for Trypanosoma cruzi identification from other closely related species. Additionally, we combined the sequences of cox1 and the nuclear gene glucose-6-phosphate isomerase (GPI) to evaluate the occurrence of mitochondrial introgression and the presence of hybrid genotypes...
October 16, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29034987/global-scale-impacts-of-nitrogen-deposition-on-tree-carbon-sequestration-in-tropical-temperate-and-boreal-forests-a-meta-analysis
#16
Lena Schulte-Uebbing, Wim de Vries
Elevated nitrogen (N) deposition may increase net primary productivity in N-limited terrestrial ecosystems and thus enhance the terrestrial carbon (C) sink. To assess the magnitude of this N-induced C sink, we performed a meta-analysis on data from forest fertilization experiments to estimate N-induced C sequestration in aboveground tree woody biomass, a stable C pool with long turnover times. Our results show that boreal and temperate forests responded strongly to N addition and sequestered on average an additional 14 and 13 kg C per kg N in aboveground woody biomass, respectively...
October 16, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29031009/fabrication-of-biodegradable-foams-for-deep-tissue-negative-pressure-treatments
#17
Harleigh J Warner, William D Wagner
Devices for negative pressure wound therapy (NPWT) rely on compressible foams operating at the tissue-device interface. Clinically used foams are nonabsorbable and if used on deep wounds or left in place for an extended period of time, excessive cell ingrowth and formation of granulation tissue into the foam may require a surgical procedure to remove the foam. Foams with fast degradation and with low immunogenicity and fibrotic response are required. Foams composed of combinations of poly(lactide-co-glycolide) (PLGA), poly(lactide-co-caprolactone) (PLCL), and polycaprolactone (PCL) were created by combined salt leaching and solvent displacement protocols...
October 14, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29030907/macromolecular-rate-theory-mmrt-provides-a-thermodynamics-rationale-to-underpin-the-convergent-temperature-response-in-plant-leaf-respiration
#18
Liyin L Liang, Vickery L Arcus, Mary A Heskel, Odhran S O'Sullivan, Lasantha K Weerasinghe, Danielle Creek, John J G Egerton, Mark G Tjoelker, Owen K Atkin, Louis A Schipper
Temperature is a crucial factor in determining the rates of ecosystem processes, e.g. leaf respiration (R) - the flux of plant respired CO2 from leaves to the atmosphere. Generally, R increases exponentially with temperature and formulations such as the Arrhenius equation are widely used in earth system models. However, experimental observations have shown a consequential and consistent departure from an exponential increase in R. What are the principles that underlie these observed patterns? Here, we demonstrate that macromolecular rate theory (MMRT), based on transition state theory for enzyme-catalyzed kinetics, provides a thermodynamic explanation for the observed departure and the convergent temperature response of R using a global database...
October 14, 2017: Global Change Biology
https://www.readbyqxmd.com/read/29029319/new-records-of-phlebotomine-sand-flies-diptera-psychodidae-from-the-state-of-alagoas-northeast-of-brazil
#19
Moises Thiago de Souza Freitas, Carlos Fernando Rocha Dos Santos, Edilberto Marinho de Andrade, Carlos Brisola Marcondes, Valdir de Queiroz Balbino, Felipe Arley Costa Pessoa
Phlebotomine sand flies are small insects of great medical importance. This study presents new records of phlebotomine sand flies, which augment the list of species, recorded in the state of Alagoas, Brazil. Sand flies were collected using CDC miniature light traps. Collections were made between November 2008 and April 2016, in 47 municipalities within the state of Alagoas. Twenty-seven thousand two-hundred forty-four sand flies were collected, representing 18 species in seven genera. Lutzomyia longipalpis was the predominant species (85...
October 4, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/29026013/oco-2-advances-photosynthesis-observation-from-space-via-solar-induced-chlorophyll-fluorescence
#20
Y Sun, C Frankenberg, J D Wood, D S Schimel, M Jung, L Guanter, D T Drewry, M Verma, A Porcar-Castell, T J Griffis, L Gu, T S Magney, P Köhler, B Evans, K Yuen
Quantifying gross primary production (GPP) remains a major challenge in global carbon cycle research. Spaceborne monitoring of solar-induced chlorophyll fluorescence (SIF), an integrative photosynthetic signal of molecular origin, can assist in terrestrial GPP monitoring. However, the extent to which SIF tracks spatiotemporal variations in GPP remains unresolved. Orbiting Carbon Observatory-2 (OCO-2)'s SIF data acquisition and fine spatial resolution permit direct validation against ground and airborne observations...
October 13, 2017: Science
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