Ranjiv Mathews, Myra Carpenter, Russell Chesney, Alejandro Hoberman, Ron Keren, Tej Mattoo, Marva Moxey-Mims, Lee Nyberg, Saul Greenfield
UNLABELLED: The current management of vesicoureteral reflux (VUR) focuses on the prevention of urinary tract infections (UTI), with curative surgery being limited to those children that fail conservative measures. This is based on the assumption that UTIs are preventable with the use of prophylatic antibiotics, leading to reduction of renal scarring, and the possibility that VUR in children can resolve spontaneously. METHODS: Review of the recent literature has demonstrated a growing concern that antibiotic prophylaxis may not lead to prevention of UTIs...
October 2009: Journal of Pediatric Urology