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diabetic ketoacidosis diagnosis

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https://www.readbyqxmd.com/read/29903409/validation-of-data-from-electronic-data-warehouse-in-diabetic-ketoacidosis-caution-is-needed
#1
Jennifer VanderWeele, Teresa Pollack, Diana Johnson Oakes, Colleen Smyrniotis, Vidhya Illuri, Priyathama Vellanki, Kevin O'Leary, Jane Holl, Grazia Aleppo, Mark E Molitch, Amisha Wallia
AIMS: This study validated enterprise data warehouse (EDW) data for a cohort of hospitalized patients with a primary diagnosis of diabetic ketoacidosis (DKA). METHODS: 247 patients with 319 admissions for DKA (ICD-9 code 250.12, 250.13, or 250.xx with biochemical criteria for DKA) were admitted to Northwestern Memorial Hospital from 1/1/2010 to 9/1/2013. Validation was performed by electronic medical record (EMR) review of 10% of admissions (N = 32). Classification of diabetes type (Type 1 vs...
May 8, 2018: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/29862967/thanatobiochemistry-post-mortem-study-of-the-vitreous-humor-for-the-diagnosis-of-diabetic-ketoacidosis-death
#2
Guillaume Rousseau, Nicolas Bergerat, Guillaume Drevin, Pascal Reynier, Nathalie Jousset
Thanatobiochemistry refers to a post mortem study of biochemical parameters enabling to shed light on a cause of death. This discipline shines when suspected lethal pathology doesn't have any noticeable macroscopic or microscopic features such as diabetic ketoacidosis. We relate the case of fourty-five years old patient followed-up for type I diabetes mellitus, discovered dead at home, for which only post mortem biochemical exploration of vitreous humor allowed to determine the cause of death by diabetic ketoacidosis...
June 1, 2018: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/29850300/young-man-with-hepatomegaly-a-case-of-glycogenic-hepatopathy
#3
Walid Abboud, Saif Abdulla, Mohammed Al Zaabi, Ramzi Moufarrej
Glycogenic hepatopathy is a rare but potentially reversible condition characterized by hepatomegaly and elevated liver enzymes occurring in poorly controlled type 1 diabetes mellitus patients and often requires a liver biopsy to confirm the diagnosis. We present the case of a young man who was admitted with diabetic ketoacidosis in the setting of poorly controlled diabetes mellitus type 1 and was noted to have significantly elevated transaminases that continued to worsen despite appropriate treatment of the diabetic ketoacidosis...
2018: Case Reports in Hepatology
https://www.readbyqxmd.com/read/29849291/sodium-glucose-cotransporter-2-induced-diabetic-ketoacidosis-with-minimal-hyperglycemia
#4
D Taylor Gammons, Francis L Counselman
The case of a 56-year-old man with a history of type 2 diabetes mellitus who presented to the emergency department in diabetic ketoacidosis (DKA) with only mild hyperglycemia is presented. The patient was taking empagliflozin (Jardiance®), a sodium-glucose cotransporter -2 inhibitor, which has now been recognized as causing this unusual presentation of DKA. Emergency physicians need to be aware of this complication, as the euglycemia/mild hyperglycemia and a history of type 2 diabetes mellitus can make the correct diagnosis of DKA a challenge...
February 2018: Clinical practice and cases in emergency medicine
https://www.readbyqxmd.com/read/29805204/comparative-occurrence-of-diabetes-in-canine-feline-and-few-wild-animals-and-their-association-with-pancreatic-diseases-and-ketoacidosis-with-therapeutic-approach
#5
REVIEW
Kamal Niaz, Faheem Maqbool, Fazlullah Khan, Fatima Ismail Hassan, Saeideh Momtaz, Mohammad Abdollahi
Diabetes mellitus (DM) is a chronic metabolic disorder in which blood glucose level raises that can result in severe complications. However, the incidence increased mostly by obesity, pregnancy, persistent corpus luteum, and diestrus phase in humans and animals. This review has focused on addressing the possible understanding and pathogenesis of spontaneous DM in canine, feline, and few wild animals. Furthermore, pancreatic associated disorders, diabetic ketoacidosis, hormonal and drug interaction with diabetes, and herbal remedies associated with DM are elucidated...
April 2018: Veterinary World
https://www.readbyqxmd.com/read/29774417/first-report-on-the-nationwide-incidence-of-type-1-diabetes-and-ketoacidosis-at-onset-in-children-in-serbia-a-multicenter-study
#6
Rade Vukovic, Maja D Jesic, Ivana Vorgucin, Sandra Stankovic, Nevena Folic, Tatjana Milenkovic, Silvija Sajic, Dragan Katanic, Sasa Zivic, Slavica Markovic, Ivan Soldatovic
Data regarding incidence of type 1 diabetes (T1DM), as well as data on frequency and severity of diabetic ketoacidosis (DKA) at the time of T1DM diagnosis is of paramount importance for national and regional healthcare planning. The aim of present multicenter study was to provide the first report regarding nationwide annual incidence rates for T1DM in youth in Serbia, as well as prevalence of DKA at the time of diagnosis. Data on all pediatric patients with newly diagnosed T1DM was retrospectively collected from all 15 regional centers for pediatric diabetes in Serbia during the period 2007-2017...
May 17, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29773640/health-care-utilization-and-burden-of-diabetic-ketoacidosis-in-the-u-s-over-the-past-decade-a-nationwide-analysis
#7
Dimpi Desai, Dhruv Mehta, Priyanka Mathias, Gopal Menon, Ulrich K Schubart
OBJECTIVE: Diabetes is one of the most common chronic diseases and a leading cause of morbidity and mortality in the U.S. Although our ability to treat diabetes and its associated complications has significantly improved, presentation with uncontrolled diabetes leading to ketoacidosis remains a significant problem. RESEARCH DESIGN AND METHODS: We aimed to determine the incidence and costs of hospital admissions associated with diabetic ketoacidosis (DKA). We reviewed the National Inpatient Sample Database for all hospitalizations in which DKA (ICD-9 codes 250...
May 17, 2018: Diabetes Care
https://www.readbyqxmd.com/read/29768296/pediatric-diabetic-ketoacidosis-with-hypotensive-shock-and-rash-an-unusual-presentation
#8
Yehonatan Pasternak, Omer Niv, Yehezkel Hezi Waisman
We describe a previously healthy adolescent boy who presented with respiratory distress, hypotensive shock, and a diffuse erythematous rash. The final diagnosis was diabetic ketoacidosis. Caregivers should be alert to this unusual combination of symptoms in the emergency department setting in order to improve the recognition and management of children with new-onset diabetes.
May 15, 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29735574/management-of-type-1-diabetes-with-a-very-low-carbohydrate-diet
#9
Belinda S Lennerz, Anna Barton, Richard K Bernstein, R David Dikeman, Carrie Diulus, Sarah Hallberg, Erinn T Rhodes, Cara B Ebbeling, Eric C Westman, William S Yancy, David S Ludwig
OBJECTIVES: To evaluate glycemic control among children and adults with type 1 diabetes mellitus (T1DM) who consume a very low-carbohydrate diet (VLCD). METHODS: We conducted an online survey of an international social media group for people with T1DM who follow a VLCD. Respondents included adults and parents of children with T1DM. We assessed current hemoglobin A1c (HbA1c) (primary measure), change in HbA1c after the self-reported beginning of the VLCD, total daily insulin dose, and adverse events...
May 7, 2018: Pediatrics
https://www.readbyqxmd.com/read/29716801/eruptive-xanthoma-in-the-setting-of-hypertriglyceridemia-and-pancreatitis
#10
Matthew Stark, Jonathan Stuart
BACKGROUND: Undifferentiated dermatologic complaints are often encountered in the emergency department. While a patient's exposures, risk factors, and comorbidities may help guide emergency department evaluation, the accurate diagnosis of dermatologic findings is critical to allowing rapid identification and treatment of disease. CASE: In this vignette we discuss a case of eruptive xanthoma in a 33-year-old male with diabetic ketoacidosis and pancreatitis. DISCUSSION: Dermatologic complaints pose a unique challenge to the emergency physician...
April 25, 2018: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29692258/early-occurrence-cases-of-diabetes-mellitus-clinical-picture-in-two-major-tertiary-care-hospitals-in-india
#11
Nitin Joseph, Shreya Sharma, Vinisha Modi, Sanath Majunatha, Saad Arshad Siddiqui, Mihika Sinha
INTRODUCTION: Type 1 diabetes mellitus (T1D) is one of the most common endocrine disease in childhood. However, very limited information is available on this disease. OBJECTIVES: This study was done to assess risk factors, clinical features and management practices in T1D patients. METHODS: A review of records of 39 T1D cases admitted over the past five years in two hospitals was done. RESULTS: The mean age at diagnosis among males was 19...
April 24, 2018: Current Diabetes Reviews
https://www.readbyqxmd.com/read/29672561/rich-table-but-short-life-diffuse-idiopathic-skeletal-hyperostosis-in-danish-astronomer-tycho-brahe-1546-1601-and-its-possible-consequences
#12
Sacha Kacki, Petr Velemínský, Niels Lynnerup, Sylva Kaupová, Alizé Lacoste Jeanson, Ctibor Povýšil, Martin Horák, Jan Kučera, Kaare Lund Rasmussen, Jaroslav Podliska, Zdeněk Dragoun, Jiří Smolík, Jens Vellev, Jaroslav Brůžek
The exhumation of Danish astronomer Tycho Brahe (1546-1601) was performed in 2010 to verify speculative views on the cause of his death. Previous analyses of skeletal and hair remains recovered from his grave refuted the presumption that he died from poisoning. These studies also outlined the possibility that he actually died from an acute illness, echoing the rather vague and inaccurate testimony of some historical records. We performed a detailed paleopathological analysis of Tycho Brahe's skeletal remains, along with a reconstruction of his diet based on carbon and nitrogen stable isotopes analysis and an estimate of his physical status (relative body fat) based on medullar and cortical dimensions of the femoral shaft...
2018: PloS One
https://www.readbyqxmd.com/read/29666080/eye-for-an-eye-near-fatal-outcome-of-fungal-infection-in-a-young-diabetic-girl
#13
Fedja I Vos, Sietze Reitsma, Gwijde F J P M Adriaensen, Wytske J Fokkens
In this report, we describe the case of a young, diabetic girl with ketoacidosis who suffered sudden loss of vision of the right eye. The loss of vision was caused by an invasive rhino-orbital-cerebral fungal infection (mucormycosis) with extensive periorbital thrombosis. Despite maximal antifungal and surgical treatment (including exenteration of the right orbit), the clinical situation deteriorated. It was only after overcoming the difficulties of managing her hyperglycaemia that the patient's condition stabilised and her life was saved...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29643888/spectrum-of-complications-of-severe-dka-in-children-in-pediatric-intensive-care-unit
#14
Qalab Abbas, Saba Arbab, Anwar Ul Haque, Khadija Nuzhat Humayun
Objectives: To describe the spectrum of complications of Diabetic Ketoacidosis (DKA) observed in children admitted with severe DKA. Methods: Retrospective review of the medical records of all children admitted with the diagnosis of severe DKA in Pediatric Intensive Care Unit (PICU) of the Aga Khan University Hospital, from January 2010 to December 2015 was done. Data was collected on a structured proforma and descriptive statistics were applied. Results: Total 37 children were admitted with complicated DKA (1...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29624095/external-validation-of-the-diabetes-early-readmission-risk-indicator-derri-%C3%A2
#15
Daniel J Rubin, Dominic Recco, Alexander Turchin, Huaqing Zhao, Sherita Hill Golden
OBJECTIVE: The Diabetes Early Readmission Risk Indicator (DERRI™ ) was previously developed and internally validated as a tool to predict the risk of all-cause readmission within 30 days of discharge (30-d readmission) of hospitalized patients with diabetes. In this study, the predictive performance of the DERRI™ with and without additional predictors was assessed in an external sample. METHODS: We conducted a retrospective cohort study of adult patients with diabetes discharged from 2 academic medical centers between 1/1/2000 and 12/31/2014...
April 6, 2018: Endocrine Practice
https://www.readbyqxmd.com/read/29622578/relationship-between-islet-autoantibody-status-and-the-clinical-characteristics-of-children-and-adults-with-incident-type-1-diabetes-in-a-uk-cohort
#16
Vassiliki Bravis, Akaal Kaur, Helen C Walkey, Ian F Godsland, Shivani Misra, Polly J Bingley, Alistair J K Williams, David B Dunger, Colin M Dayan, Mark Peakman, Nick S Oliver, Desmond G Johnston
OBJECTIVES: To describe the characteristics of children and adults with incident type 1 diabetes in contemporary, multiethnic UK, focusing on differences between the islet autoantibody negative and positive. DESIGN: Observational cohort study. SETTING: 146 mainly secondary care centres across England and Wales. PARTICIPANTS: 3312 people aged ≥5 years were recruited within 6 months of a clinical diagnosis of type 1 diabetes via the National Institute for Health Research Clinical Research Network...
April 4, 2018: BMJ Open
https://www.readbyqxmd.com/read/29600548/acute-invasive-fungal-rhinosinusitis-in-twenty-one-diabetic-patients
#17
LETTER
P-W Wu, Y-L Huang, S-W Yang, Y-S Lee, C-C Huang, P-H Chang, C-C Huang, T-J Lee
No abstract text is available yet for this article.
March 30, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29600506/prediabetes-directly-deteriorates-into-diabetic-ketoacidosis-and-hyperosmolar-hyperglycemic-syndrome-triggered-by-acute-pancreatitis-a-case-report-illustrating-a-chicken-and-egg-paradigm-in-ketosis-prone-diabetes
#18
Runbo Song, Shanjin Cao
INTRODUCTION: Diabetic crises occur most often in patients with type 1 diabetes and occasionally in type 2 diabetes, especially under stressful conditions. However, a diabetic crisis occurring directly from prediabetes is an unusual phenomenon. CASE REPORT: A 45-year-old woman presented with postprandial left upper quadrant abdominal pain, nausea, and vomiting. She had a past medical history of prediabetes with impaired fasting glucose and HbA1c 6.4%. On admission, routine laboratory tests showed high anion gap metabolic acidosis (pH 6...
March 29, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29575401/previously-undiagnosed-attention-deficit-hyperactivity-disorder-associated-with-poor-metabolic-control-in-adolescents-with-type-1-diabetes
#19
C Nylander, K Lindström, N Khalifa, E Fernell
BACKGROUND: Managing modern diabetes treatment requires efficient executive functions. Patients with attention-deficit/hyperactivity disorder (ADHD) and type 1 diabetes have poor metabolic control and present with ketoacidosis more often than patients without ADHD. OBJECTIVE: To assess whether patients with type 1 diabetes and with indications of executive problems met criteria for ADHD, and to investigate whether these patients had difficulties achieving metabolic control...
June 2018: Pediatric Diabetes
https://www.readbyqxmd.com/read/29568778/integration-of-routine-parameters-of-glycemic-variability-in-a-simple-screening-method-for-partial-remission-in-children-with-type-1-diabetes
#20
Nina Nielens, Olivier Pollé, Annie Robert, Philippe A Lysy
Although different criteria were used to define partial remission in type 1 diabetes, the IDAA1C formula has prevailed as it correlates with stimulated C-peptide levels. Our retrospective study evaluated clinical variables associated with the occurrence of IDAA1C-defined partial remission in a series of 239 pediatric patients. Diabetic ketoacidosis and age at diagnosis, but no other clinical feature, influenced the occurrence of remission. We then evaluated whether parameters of glycemic variability used in clinical routine may reliably define partial remission, as these would alleviate confounding factors related to insulin treatment...
2018: Journal of Diabetes Research
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