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https://www.readbyqxmd.com/read/28350750/family-history-comorbidity-smoking-and-other-risk-factors-in-microscopic-colitis-a-case-control-study
#1
Anna Wickbom, Nils Nyhlin, Scott M Montgomery, Johan Bohr, Curt Tysk
OBJECTIVES: Data on heredity, risk factors and comorbidity in microscopic colitis, encompassing collagenous colitis (CC) and lymphocytic colitis (LC), are limited. AIM: The aim was to carry out a case-control study of family history, childhood circumstances, educational level, marital status, smoking and comorbidity in microscopic colitis. METHODS: A postal questionnaire was sent in 2008-2009 to microscopic colitis patients resident in Sweden and three population-based controls per patient, matched for age, sex and municipality...
May 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28344669/belimumab-in-systemic-lupus-erythematosus-sle-evidence-to-date-and-clinical-usefulness
#2
REVIEW
Sara Guerreiro Castro, David A Isenberg
Systemic lupus erythematosus (SLE) is a complex autoimmune rheumatic disease with multiple presentations, whose management presents many challenges. Many disease modifying or immunosuppressive drugs have been used with limited success, especially in patients with more severe disease activity. Belimumab is the first drug to be approved specifically for the treatment of SLE in more than 50 years. By blocking the B-cell activating factor, it interferes in B-cell differentiation and survival. Here we consider the results of the clinical trials that led to its approval, as well as the post-hoc analyses, follow-up studies and the current trials...
March 2017: Therapeutic Advances in Musculoskeletal Disease
https://www.readbyqxmd.com/read/28344613/anp-and-bnp-plasma-levels-in-patients-with-rheumatic-mitral-stenosis-after-percutaneous-balloon-mitral-valvuloplasty
#3
Łukasz Mazurkiewicz, Witold Rużyłło, Zbigniew Chmielak, Ewa Opalińska-Ciszek, Jadwiga Janas, Piotr Hoffman, Tomasz Hryniewiecki, Jacek Grzybowski
INTRODUCTION: Atrial (ANP) and B-type (BNP) natriuretic peptides are hormones secreted by the heart as a response to volume expansion and pressure overload. AIM: To assess the changes of ANP and BNP after percutaneous balloon mitral valvuloplasty (PBMV) and to investigate factors associated with endpoints. MATERIAL AND METHODS: The study included 96 patients (90.7% females, age 51.6 ±12.2 years) with rheumatic mitral valve stenosis (mitral valve area (MVA) 1...
2017: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/28343623/biological-therapy-and-development-of-neoplastic-disease-in-patients-with-juvenile-rheumatic-disease-a-systematic-review
#4
Vanessa Patricia L Pereira, Teresa Cristina Martins Vicente Robazzi
Juvenile rheumatic diseases affect the musculoskeletal system and begin before the age of 18. These conditions have varied, identifiable or unknown etiologies, but those of an autoimmune inflammatory nature have been associated with an increased risk of development of cancer, regardless of treatment. This study aims to assess, through a systematic review of the literature according to Prisma (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) quality criteria, the risk of cancer in patients with juvenile rheumatic disease, and its association with biological agents...
March 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28342706/emotional-and-behavioral-influence-of-headache-in-pediatric-rheumatic-diseases
#5
Burak Dogangun, Mustafa Emir Tavsanli, Ezgi Sen, Murat Guntel, Ozgur Kasapcopur, Melis Sohtaoglu, Erdal Yanardoner Stat, Sabahattin Saip, Derya Uluduz
No abstract text is available yet for this article.
March 22, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28342542/determinants-of-late-tricuspid-regurgitation-after-aortic-mitral-double-valve-replacement
#6
Dong Seop Jeong, Pyo Won Park, Kiick Sung, Wook Sung Kim, Young Tak Lee
The aims of this study are to evaluate the long-term outcomes of double valve replacement (aortic and mitral valves) and to investigate the determinants of late tricuspid regurgitation (TR). A total of 239 consecutive patients who underwent double valve replacement were enrolled. Valve pathology was rheumatic in 86.6% (207/239) and degenerative in 13.4% (32/239) of patients. Among these patients, 116 patients underwent concomitant tricuspid annuloplasty, and follow-up was completed for all 239 patients (mean = 7...
March 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28342151/cardiovascular-disease-in-rheumatoid-arthritis-medications-and-risk-factors-in-china
#7
Chun Li, X R Wang, H J Ji, X Y Zhang, X F Li, L Z Wang, C H Wang, Y F Wang, Rong Yang, G C Wang, Xin Lu, Ping Zhu, L N Chen, H T Jin, J T Liu, X Y Liu, Lin Sun, H Y Chen, Ping Wei, J X Wang, L F Cui, Rong Shu, B L Liu, Z L Zhang, G T Li, Z B Li, Jing Yang, J F Li, Bin Jia, F X Zhang, J M Tao, S L Han, J Y Lin, M Q Wei, X M Liu, Dan Ke, S X Hu, Cong Ye, X Y Yang, Hao Li, C B Huang, Ming Gao, Bei Lai, X F Li, L J Song, Yi Wang, X Y Wang, Y D Tang, Yin Su, Rong Mu, Z G Li
This study aims to assess the risk factors of cardiovascular disease (CVD) and to determine the association of traditional and biologic disease-modifying anti-rheumatic drugs (DMARDs) with risk for CVD in Chinese rheumatoid arthritis (RA) patients. A cross-sectional cohort of 2013 RA patients from 21 hospitals around China was established. Medical history of CVD was documented. The patients' social background, clinical manifestations, comorbidities, and medications were also collected. Of the 2013 patients, 256 had CVD with an incidence of 12...
March 24, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28339817/bsr-and-bhpr-guideline-for-the-prescription-and-monitoring-of-non-biologic-disease-modifying-anti-rheumatic-drugs
#8
Jo Ledingham, Nicola Gullick, Katherine Irving, Rachel Gorodkin, Melissa Aris, Jean Burke, Patrick Gordon, Dimitrios Christidis, Sarah Galloway, Eranga Hayes, Andrew Jeffries, Scott Mercer, Janice Mooney, Sander van Leuven, James Galloway
No abstract text is available yet for this article.
February 27, 2017: Rheumatology
https://www.readbyqxmd.com/read/28339632/dosing-down-with-biologic-therapies-a-systematic-review-and-clinicians-perspective
#9
Christopher J Edwards, Bruno Fautrel, Hendrik Schulze-Koops, Tom W J Huizinga, Klaus Kruger
The effectiveness of biologic therapies now means that remission or low disease activity are realistic targets for treatment. However, after achieving remission/low disease activity, the next steps remain unclear. The aim of this publication was to conduct a broad systematic literature review to evaluate dosing down of biologics. After screening papers and abstracts for relevance and application of inclusion/exclusion criteria, a structured extraction process was used to collect information on the included studies...
February 16, 2017: Rheumatology
https://www.readbyqxmd.com/read/28338619/role-and-function-of-a2a-and-a%C3%A2-adenosine-receptors-in-patients-with-ankylosing-spondylitis-psoriatic-arthritis-and-rheumatoid-arthritis
#10
Annalisa Ravani, Fabrizio Vincenzi, Alessandra Bortoluzzi, Melissa Padovan, Silvia Pasquini, Stefania Gessi, Stefania Merighi, Pier Andrea Borea, Marcello Govoni, Katia Varani
Rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) are chronic inflammatory rheumatic diseases that affect joints, causing debilitating pain and disability. Adenosine receptors (ARs) play a key role in the mechanism of inflammation, and the activation of A2A and A₃AR subtypes is often associated with a reduction of the inflammatory status. The aim of this study was to investigate the involvement of ARs in patients suffering from early-RA (ERA), RA, AS and PsA. Messenger RNA (mRNA) analysis and saturation binding experiments indicated an upregulation of A2A and A₃ARs in lymphocytes obtained from patients when compared with healthy subjects...
March 24, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28336519/anticollagen-type-ii-antibodies-are-associated-with-an-acute-onset-rheumatoid-arthritis-phenotype-and-prognosticate-lower-degree-of-inflammation-during-5%C3%A2-years-follow-up
#11
Vivek Anand Manivel, Mohammed Mullazehi, Leonid Padyukov, Helga Westerlind, Lars Klareskog, Lars Alfredsson, Saedis Saevarsdottir, Johan Rönnelid
OBJECTIVE: Antifibrillar collagen type II (anti-CII) antibody-positive patients with rheumatoid arthritis (RA) have early but not late signs of increased inflammation and joint erosions. We wanted to replicate this in a large RA cohort, and to relate to human leukocyte antigen (HLA)-DRB1* alleles. METHODS: Anti-CII and anti-cyclic citrullinated peptide (CCP)2 were measured at baseline in 773 patients with RA from the Swedish Epidemiological Investigation in Rheumatoid Arthritis (EIRA) study with clinical follow-up data from the Swedish Rheumatology Quality Register (SRQ) registry, and 1476 with HLA-DRB1* information...
March 23, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28336386/the-whf-roadmap-for-reducing-cv-morbidity-and-mortality-through-prevention-and-control-of-rheumatic-heart-disease
#12
Benjamin Palafox, Ana Olga Mocumbi, R Krishna Kumar, Sulafa K M Ali, Elizabeth Kennedy, Abraham Haileamlak, David Watkins, Kadia Petricca, Rosemary Wyber, Patrick Timeon, Jeremiah Mwangi
Rheumatic heart disease (RHD) is a preventable non-communicable condition that disproportionately affects the world's poorest and most vulnerable. The World Heart Federation Roadmap for improved RHD control is a resource designed to help a variety of stakeholders raise the profile of RHD nationally and globally, and provide a framework to guide and support the strengthening of national, regional and global RHD control efforts. The Roadmap identifies the barriers that limit access to and uptake of proven interventions for the prevention and control of RHD...
March 20, 2017: Global Heart
https://www.readbyqxmd.com/read/28331208/metabolic-regulation-of-inflammation
#13
REVIEW
Timo Gaber, Cindy Strehl, Frank Buttgereit
Immune cells constantly patrol the body via the bloodstream and migrate into multiple tissues where they face variable and sometimes demanding environmental conditions. Nutrient and oxygen availability can vary during homeostasis, and especially during the course of an immune response, creating a demand for immune cells that are highly metabolically dynamic. As an evolutionary response, immune cells have developed different metabolic programmes to supply them with cellular energy and biomolecules, enabling them to cope with changing and challenging metabolic conditions...
March 23, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28330998/comparison-of-performance-of-the-2016-acr-eular-classification-criteria-for-primary-sj%C3%A3-gren-s-syndrome-with-other-sets-of-criteria-in-japanese-patients
#14
Hiroto Tsuboi, Shinya Hagiwara, Hiromitsu Asashima, Hiroyuki Takahashi, Tomoya Hirota, Hisashi Noma, Hisanori Umehara, Atsushi Kawakami, Hideki Nakamura, Hajime Sano, Kazuo Tsubota, Yoko Ogawa, Etsuko Takamura, Ichiro Saito, Hiroko Inoue, Seiji Nakamura, Masafumi Moriyama, Tsutomu Takeuchi, Yoshiya Tanaka, Shintaro Hirata, Tsuneyo Mimori, Isao Matsumoto, Takayuki Sumida
OBJECTIVES: To compare the performance of the new 2016 American College of Rheumatology (ACR)-European League Against Rheumatism (EULAR) classification criteria for primary Sjögren's syndrome (SS) with 1999 revised Japanese Ministry of Health criteria for diagnosis of SS (JPN), 2002 American-European Consensus Group classification criteria for SS (AECG) and 2012 ACR classification criteria for SS (ACR) in Japanese patients. METHODS: The study subjects were 499 patients with primary SS (pSS) or suspected pSS who were followed up in June 2012 at 10 hospitals in Japan...
March 22, 2017: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/28330716/the-value-of-power-doppler-ultrasound-in-patients-with-rheumatoid-arthritis-in-clinical-remission-reclassifying-disease-activity
#15
Facundo Vergara, Santiago Ruta, Javier Rosa, Josefina Marín, Ricardo García-Mónaco, Enrique R Soriano
OBJECTIVES: The aim of the present study was to describe the ultrasound (US) findings in patients with rheumatoid arthritis (RA) in clinical remission, and to evaluate the ability of power Doppler (PD) US to reclassify disease activity in these patients. MATERIAL AND METHODS: We included consecutive patients with RA according to 2010 American College of Rheumatology/European League Against Rheumatism criteria, who were in clinical remission by the Disease Activity Score (DAS28<2...
March 18, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28329330/three-port-one-incision-plus-two-port-endoscopic-mitral-valve-surgery-without-robotic-assistance%C3%A2
#16
Toshiaki Ito, Atsuo Maekawa, Satoshi Hoshino, Yasunari Hayashi, Sadanari Sawaki, Junji Yanagisawa, Masayoshi Tokoro
OBJECTIVES: Totally endoscopic minimally invasive mitral valve surgery (MIMVS) is technically demanding and often performed with robotic assistance. We hypothesized that three-port video-assisted thoracic surgery (VATS) would facilitate endoscopic MIMVS and evaluated its feasibility and safety. METHODS: From October 2010 to June 2016, we performed first-time MIMVS in 250 consecutive patients (122 male), with median age of 65 years (54-73 years, 25-75 percentile)...
March 17, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28328528/ocimum-gratissimum-linn-leaf-extract-inhibits-free-radical-generation-and-suppressed-inflammation-in-carrageenan-induced-inflammation-models-in-rats
#17
Abayomi M Ajayi, Mary O Ologe, Benneth Ben-Azu, Samuel E Okhale, Bulus Adzu, Olusegun G Ademowo
BACKGROUND: Ocimum gratissimum leaf is used in managing rheumatism and other inflammatory conditions. In this study, we investigated the antioxidant and anti-inflammatory effects of phenolic extract obtained by sequential methanol extraction of O. gratissimum leaves (MEOg). METHODS: The methanol extract (MEOg) was obtained after sequential maceration (n-hexane, chloroform and methanol) of dried O. gratissimum leaves. The fingerprint of the extract was obtained using a high-performance liquid chromatrographic method...
March 22, 2017: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/28328178/clinical-characteristics-of-multifocal-osteonecrosis-in-korean-patients-with-rheumatic-disease
#18
Hye-Jin Jeong, Dam Kim, Soo-Kyung Cho, Yeesuk Kim, Sang-Cheol Bae, Yoon-Kyoung Sung
AIM: Osteonecrosis (ON), also known as avascular necrosis, is an important cause of physical disability in rheumatic disease. When this condition affects multiple structures, disability is increased. The purpose of this study was to describe the clinical characteristics of Korean patients with multifocal ON associated with rheumatic disease and to compare them with those of previously reported cases. METHODS: We reviewed the clinical characteristics of eight Korean patients with multifocal ON, defined by the involvement of three or more anatomic sites, associated with rheumatic disease in a single referral academic hospital, and compared them with those of 19 similar cases previously reported in the literature...
March 22, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28328098/plasma-exchange-successfully-treated-macrophage-activation-syndrome-in-rheumatoid-factor-positive-polyarticular-juvenile-idiopathic-arthritis-with-combined-pneumonia
#19
Lianjie Shi, Fanlei Hu, Chuanhui Xu, Huaqun Zhu, Di Qie, Chuanjie Yuan, Yuhong Tao, Hanmin Liu
Macrophage activation syndrome (MAS) is one of the serious complications associated with rheumatic diseases, especially systemic juvenile idiopathic arthritis (sJIA). Here we describe a 9-year-old girl with rheumatoid factor (RF)-positive polyarticular JIA, not sJIA, combined with pneumonia who was successfully treated by plasma exchange. She was diagnosed with RF-positive polyarticular JIA based on positive RF and multiple joint swelling and tenderness 3 years ago. She was admitted in our hospital with myalgia for 2 days and a high fever for half a day...
March 22, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28328011/when-emotional-pain-becomes-physical-adverse-childhood-experiences-pain-and-the-role-of-mood-and-anxiety-disorders
#20
Natalie J Sachs-Ericsson, Julia L Sheffler, Ian H Stanley, Jennifer R Piazza, Kristopher J Preacher
OBJECTIVE: We examined the association between retrospective reports of adverse childhood experiences (ACEs) and painful medical conditions. We also examined the mediating and moderating roles of mood and anxiety disorders in the ACEs-painful medical conditions relationship. METHOD: Ten-year longitudinal data were obtained from the National Comorbidity Surveys (NCS-1, NCS-2; N = 5001). The NCS-1 obtained reports of ACEs, current health conditions, current pain severity, and mood and anxiety disorders...
March 22, 2017: Journal of Clinical Psychology
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